locus-tag	class	description
DKE46_000010	COG0592	DNA-directed DNA polymerase activity
DKE46_000065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DKE46_000070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKE46_000155	COG2233	PERMEase
DKE46_000205	COG2814	Major facilitator Superfamily
DKE46_000210	COG0656	L-ascorbic acid biosynthetic process
DKE46_000270	COG5487	UPF0391 membrane protein
DKE46_000275	COG2983	Belongs to the UPF0260 family
DKE46_000310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE46_000330	COG1683	Conserved Protein
DKE46_000360	COG1113	amino acid transport
DKE46_000675	COG2233	PERMEase
DKE46_000680	COG2351	hydroxyisourate hydrolase activity
DKE46_000715	COG3706	GGDEF domain
DKE46_000735	COG0708	Exodeoxyribonuclease III
DKE46_000775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKE46_000800	COG4942	peptidase
DKE46_000830	COG0426	domain, Protein
DKE46_000830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE46_000870	COG1902	pentaerythritol trinitrate reductase activity
DKE46_000880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKE46_000905	COG1522	sequence-specific DNA binding
DKE46_000910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE46_000935	COG3162	membrane
DKE46_000975	COG1309	transcriptional regulator
DKE46_001005	COG0352	thiamine-phosphate diphosphorylase activity
DKE46_001005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE46_001005	COG0351	phosphomethylpyrimidine kinase
DKE46_001015	COG2814	Major facilitator Superfamily
DKE46_001100	COG0641	radical SAM
DKE46_001130	COG1113	amino acid transport
DKE46_001145	COG1012	belongs to the aldehyde dehydrogenase family
DKE46_001155	COG1335	isochorismatase
DKE46_001265	COG0583	DNA-binding transcription factor activity
DKE46_001370	COG2826	transposase and inactivated derivatives, IS30 family
DKE46_001430	COG2814	Major facilitator Superfamily
DKE46_001525	COG0582	viral genome integration into host DNA
DKE46_001590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DKE46_001605	COG0697	spore germination
DKE46_001630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKE46_001660	COG0427	acetyl-CoA hydrolase
DKE46_001690	COG4221	oxidoreductase activity
DKE46_001835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKE46_001915	COG1704	LemA family
DKE46_001930	COG4969	Belongs to the N-Me-Phe pilin family
DKE46_001980	COG0194	GDP metabolic process
DKE46_002030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKE46_002050	COG5380	lipid catabolic process
DKE46_002070	COG5006	permease, DMT superfamily
DKE46_002085	COG0277	FAD linked oxidase domain protein
DKE46_002095	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DKE46_002165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DKE46_002170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE46_002180	COG1012	belongs to the aldehyde dehydrogenase family
DKE46_002245	COG0752	glycyl-tRNA synthetase alpha subunit
DKE46_002275	COG1983	PspC domain protein
DKE46_002285	COG1960	acyl-CoA dehydrogenase activity
DKE46_002345	COG2854	intermembrane phospholipid transfer
DKE46_002365	COG0494	nUDIX hydrolase
DKE46_002415	COG1959	2 iron, 2 sulfur cluster binding
DKE46_002420	COG1017	nitric oxide dioxygenase activity
DKE46_002420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE46_002435	COG0626	cystathionine gamma-synthase activity
DKE46_002450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKE46_002455	COG0088	Forms part of the polypeptide exit tunnel
DKE46_002555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKE46_002590	COG1960	acyl-CoA dehydrogenase activity
DKE46_002595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DKE46_002685	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKE46_002690	COG1295	ribonuclease BN
DKE46_002735	COG1196	nuclear chromosome segregation
DKE46_002735	COG0741	lytic transglycosylase activity
DKE46_002735	COG0739	heme binding
DKE46_002765	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DKE46_002770	COG1183	phosphatidylcholine synthase activity
DKE46_002820	COG1309	transcriptional regulator
DKE46_002880	COG2969	positive regulation of protein catabolic process
DKE46_002885	COG0625	glutathione transferase activity
DKE46_002890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKE46_002900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DKE46_002945	COG1408	metallophosphoesterase
DKE46_003010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE46_003010	COG3453	Protein conserved in bacteria
DKE46_003025	COG1607	acyl-coa hydrolase
DKE46_003085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DKE46_003100	COG1862	Preprotein translocase
DKE46_003160	COG0726	polysaccharide deacetylase
DKE46_003225	COG0625	glutathione transferase activity
DKE46_003230	COG0583	DNA-binding transcription factor activity
DKE46_003235	COG1960	acyl-CoA dehydrogenase activity
DKE46_003285	COG2096	Adenosyltransferase
DKE46_003300	COG0133	tryptophan synthase activity
DKE46_003375	COG0477	Major facilitator Superfamily
DKE46_003380	COG1272	protein, Hemolysin III
DKE46_003390	COG2153	protein acetylation
DKE46_003415	COG2207	Transcriptional regulator
DKE46_003435	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE46_003465	COG2885	chlorophyll binding
DKE46_003465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DKE46_003485	COG2233	PERMEase
DKE46_003515	COG2094	Belongs to the DNA glycosylase MPG family
DKE46_003525	COG1902	pentaerythritol trinitrate reductase activity
DKE46_003530	COG0679	Auxin Efflux Carrier
DKE46_003540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DKE46_003570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE46_003575	COG0251	oxidation-reduction process
DKE46_003580	COG1335	isochorismatase
DKE46_003585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE46_003590	COG0778	Nitroreductase
DKE46_003595	COG0596	Alpha beta hydrolase
DKE46_003600	COG3189	MarR family transcriptional regulator
DKE46_003610	COG3422	double-strand break repair
DKE46_003670	COG5510	response to toxic substance
DKE46_003680	COG2832	Protein of unknown function (DUF454)
DKE46_003775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKE46_003820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE46_003830	COG1792	Involved in formation and maintenance of cell shape
DKE46_003835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DKE46_003855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE46_003900	COG2207	Transcriptional regulator
DKE46_003930	COG3046	protein related to deoxyribodipyrimidine photolyase
DKE46_003955	COG2315	Protein conserved in bacteria
DKE46_003980	COG1752	Esterase of the alpha-beta hydrolase superfamily
DKE46_004030	COG0004	ammonium transporteR
DKE46_004035	COG0583	DNA-binding transcription factor activity
DKE46_004070	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_004150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKE46_004205	COG2921	Belongs to the UPF0250 family
DKE46_004250	COG2009	succinate dehydrogenase
DKE46_004255	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DKE46_004260	COG1053	succinate dehydrogenase
DKE46_004265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DKE46_004315	COG2321	neutral zinc metallopeptidase
DKE46_004385	COG0589	response to stress
DKE46_004400	COG1309	transcriptional regulator
DKE46_004415	COG0505	Belongs to the CarA family
DKE46_004720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE46_004750	COG0584	glycerophosphoryl diester phosphodiesterase
DKE46_004770	COG0741	lytic transglycosylase activity
DKE46_004870	COG0243	molybdopterin cofactor binding
DKE46_004875	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DKE46_004880	COG3339	Conserved Protein
DKE46_005000	COG1136	(ABC) transporter
DKE46_005030	COG0596	Alpha beta hydrolase
DKE46_005035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DKE46_005045	COG0628	permease
DKE46_005085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKE46_005105	COG0823	Involved in the tonB-independent uptake of proteins
DKE46_005125	COG0824	Thioesterase
DKE46_005155	COG2814	Major facilitator Superfamily
DKE46_005170	COG1051	belongs to the nudix hydrolase family
DKE46_005170	COG1056	cytidyltransferase-related domain
DKE46_005185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DKE46_005200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DKE46_005215	COG4625	pathogenesis
DKE46_005225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DKE46_005235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DKE46_005285	COG0481	GTPase activity
DKE46_005290	COG0681	Belongs to the peptidase S26 family
DKE46_005300	COG0571	ribonuclease III activity
DKE46_005330	COG4221	oxidoreductase activity
DKE46_005380	COG0556	nucleotide-excision repair
DKE46_005445	COG2070	2-Nitropropane dioxygenase
DKE46_005460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DKE46_005490	COG0415	Belongs to the DNA photolyase family
DKE46_005505	COG1686	Belongs to the peptidase S11 family
DKE46_005575	COG0352	thiamine-phosphate diphosphorylase activity
DKE46_005640	COG1522	sequence-specific DNA binding
DKE46_005655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKE46_005660	COG0573	inorganic phosphate transmembrane transporter activity
DKE46_005710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DKE46_005740	COG0583	DNA-binding transcription factor activity
DKE46_005785	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKE46_005790	COG1966	Carbon starvation protein
DKE46_005795	COG2879	small protein
DKE46_005930	COG1741	Belongs to the pirin family
DKE46_005960	COG4604	ABC transporter, ATP-binding protein
DKE46_005990	COG1535	isochorismatase
DKE46_005990	COG3433	isochorismatase activity
DKE46_006015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DKE46_006150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DKE46_006185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKE46_006190	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKE46_006195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKE46_006220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKE46_006245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE46_006250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE46_006270	COG0024	Methionine aminopeptidase
DKE46_006275	COG0052	Belongs to the universal ribosomal protein uS2 family
DKE46_006315	COG2951	lytic endotransglycosylase activity
DKE46_006385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE46_006400	COG4215	(ABC) transporter
DKE46_006405	COG4160	amino acid transport
DKE46_006420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE46_006435	COG0384	phenazine biosynthesis protein PhzF
DKE46_006445	COG1720	tRNA m6t6A37 methyltransferase activity
DKE46_006480	COG0494	nUDIX hydrolase
DKE46_006490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKE46_006495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKE46_006500	COG3139	Protein of unknown function (DUF1315)
DKE46_006505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DKE46_006515	COG1301	dicarboxylic acid transport
DKE46_006545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DKE46_006635	COG1278	Cold shock
DKE46_006640	COG0513	Belongs to the DEAD box helicase family
DKE46_006650	COG0778	Nitroreductase
DKE46_006680	COG1286	toxin biosynthetic process
DKE46_006710	COG1610	YqeY-like protein
DKE46_006715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DKE46_006850	COG1309	transcriptional regulator
DKE46_006890	COG2351	hydroxyisourate hydrolase activity
DKE46_007015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE46_007020	COG2011	ABC-type metal ion transport system permease component
DKE46_007045	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DKE46_007085	COG1305	Transglutaminase-like
DKE46_007095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKE46_007125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DKE46_007135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DKE46_007175	COG3658	cytochrome
DKE46_007200	COG0583	DNA-binding transcription factor activity
DKE46_007220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKE46_007245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE46_007260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DKE46_007290	COG0745	RESPONSE REGULATOR receiver
DKE46_007410	COG1187	pseudouridine synthase activity
DKE46_007430	COG0802	atpase or kinase
DKE46_007445	COG1923	regulation of RNA biosynthetic process
DKE46_007475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKE46_007620	COG4772	TonB-dependent receptor
DKE46_007695	COG1733	regulation of RNA biosynthetic process
DKE46_007730	COG0583	DNA-binding transcription factor activity
DKE46_007745	COG2826	transposase and inactivated derivatives, IS30 family
DKE46_007795	COG3135	benzoate transporter
DKE46_007800	COG1522	sequence-specific DNA binding
DKE46_007900	COG1335	isochorismatase
DKE46_007950	COG0069	glutamate synthase activity
DKE46_007995	COG0511	ligase activity, forming carbon-carbon bonds
DKE46_008035	COG2423	ornithine cyclodeaminase activity
DKE46_008070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE46_008095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DKE46_008110	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKE46_008110	COG0315	cyclic pyranopterin monophosphate synthase activity
DKE46_008125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE46_008155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKE46_008230	COG3852	Histidine kinase
DKE46_008295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKE46_008320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DKE46_008325	COG1011	Hydrolase
DKE46_008340	COG1522	sequence-specific DNA binding
DKE46_008445	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DKE46_008480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DKE46_008485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE46_008540	COG4890	Cyd operon protein YbgT
DKE46_008545	COG1294	oxidase, subunit
DKE46_008590	COG0569	domain protein
DKE46_008625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DKE46_008640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKE46_008695	COG0148	phosphopyruvate hydratase activity
DKE46_008715	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKE46_008725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE46_008735	COG0183	Belongs to the thiolase family
DKE46_008740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DKE46_008745	COG0596	Alpha beta hydrolase
DKE46_008750	COG2271	Major facilitator Superfamily
DKE46_008755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKE46_008765	COG3485	protocatechuate 3,4-dioxygenase
DKE46_008795	COG2391	methyltransferase activity
DKE46_008810	COG1414	Transcriptional regulator
DKE46_008905	COG3733	amine oxidase
DKE46_008925	COG0183	Belongs to the thiolase family
DKE46_008950	COG4829	muconolactone delta-isomerase
DKE46_008955	COG4948	Mandelate Racemase Muconate Lactonizing
DKE46_008970	COG2186	Transcriptional regulator
DKE46_008995	COG2351	hydroxyisourate hydrolase activity
DKE46_009015	COG2186	Transcriptional regulator
DKE46_009100	COG1309	transcriptional regulator
DKE46_009110	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_009120	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_009140	COG0318	PFAM AMP-dependent synthetase and ligase
DKE46_009270	COG1120	ATPase activity
DKE46_009280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE46_009360	COG4628	conserved protein (DUF2132)
DKE46_009375	COG3539	Fimbrial protein
DKE46_009400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DKE46_009410	COG0753	catalase activity
DKE46_009445	COG0745	RESPONSE REGULATOR receiver
DKE46_009450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE46_009515	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_009525	COG4149	molybdate abc transporter
DKE46_009550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE46_009550	COG0543	2 iron, 2 sulfur cluster binding
DKE46_009565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE46_009580	COG0412	Dienelactone hydrolase
DKE46_009595	COG2207	Transcriptional regulator
DKE46_009600	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_009665	COG0183	Belongs to the thiolase family
DKE46_009670	COG0583	DNA-binding transcription factor activity
DKE46_009690	COG1027	Aspartate ammonia-lyase
DKE46_009700	COG0477	Major facilitator Superfamily
DKE46_009720	COG2207	Transcriptional regulator
DKE46_009720	COG3708	Transcriptional regulator
DKE46_009745	COG0730	response to heat
DKE46_009785	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE46_009790	COG0022	dehydrogenase e1 component
DKE46_009795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE46_009800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE46_009845	COG0133	tryptophan synthase activity
DKE46_009890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKE46_009905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DKE46_009970	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKE46_010000	COG0730	response to heat
DKE46_010005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKE46_010025	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DKE46_010075	COG1960	acyl-CoA dehydrogenase activity
DKE46_010085	COG2207	Transcriptional regulator
DKE46_010095	COG0776	regulation of translation
DKE46_010395	COG1663	tetraacyldisaccharide 4'-kinase activity
DKE46_010400	COG1132	(ABC) transporter
DKE46_010420	COG1192	Involved in chromosome partitioning
DKE46_010445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKE46_010485	COG0640	Transcriptional regulator
DKE46_010535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE46_010550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKE46_010630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DKE46_010630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DKE46_010660	COG3539	Fimbrial protein
DKE46_010695	COG0583	DNA-binding transcription factor activity
DKE46_010760	COG1522	sequence-specific DNA binding
DKE46_010770	COG1126	abc transporter atp-binding protein
DKE46_010775	COG0765	amino acid transport
DKE46_010780	COG0765	amino acid transport
DKE46_010810	COG1464	Belongs to the NlpA lipoprotein family
DKE46_010820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKE46_010830	COG0012	GTP binding
DKE46_010855	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DKE46_010910	COG1301	dicarboxylic acid transport
DKE46_010945	COG3634	alkyl hydroperoxide reductase activity
DKE46_010965	COG0431	NADPH-dependent FMN reductase
DKE46_010980	COG0640	Transcriptional regulator
DKE46_011070	COG1271	oxidase subunit
DKE46_011075	COG1294	oxidase, subunit
DKE46_011165	COG0583	DNA-binding transcription factor activity
DKE46_011175	COG0625	glutathione transferase activity
DKE46_011215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKE46_011260	COG0765	amino acid transport
DKE46_011265	COG0765	amino acid transport
DKE46_011310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKE46_011460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE46_011465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE46_011470	COG2814	Major facilitator Superfamily
DKE46_011485	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_011535	COG2814	Major facilitator Superfamily
DKE46_011545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DKE46_011580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE46_011585	COG1414	Transcriptional regulator
DKE46_011625	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_011635	COG2050	protein possibly involved in aromatic compounds catabolism
DKE46_011645	COG3327	negative regulation of DNA-templated transcription, initiation
DKE46_011665	COG1024	Enoyl-CoA hydratase
DKE46_011670	COG1024	Enoyl-CoA hydratase
DKE46_011680	COG2151	metal-sulfur cluster biosynthetic enzyme
DKE46_011685	COG3396	Phenylacetate-CoA oxygenase
DKE46_011690	COG3460	Phenylacetate-CoA oxygenase
DKE46_011695	COG3396	Phenylacetate-CoA oxygenase
DKE46_011725	COG0789	Transcriptional regulator
DKE46_011735	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DKE46_011760	COG0590	tRNA wobble adenosine to inosine editing
DKE46_011770	COG0583	DNA-binding transcription factor activity
DKE46_011805	COG1063	alcohol dehydrogenase
DKE46_011810	COG1063	alcohol dehydrogenase
DKE46_011890	COG4770	biotin carboxylase activity
DKE46_011925	COG1595	DNA-templated transcription, initiation
DKE46_012000	COG0702	epimerase
DKE46_012095	COG3038	cytochrome b561
DKE46_012105	COG1733	regulation of RNA biosynthetic process
DKE46_012135	COG0531	amino acid
DKE46_012170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DKE46_012210	COG1538	Outer membrane efflux protein
DKE46_012220	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DKE46_012275	COG1733	regulation of RNA biosynthetic process
DKE46_012290	COG0668	transmembrane transport
DKE46_012355	COG2226	methyltransferase
DKE46_012380	COG1278	Cold shock
DKE46_012390	COG1280	lysine exporter protein (LysE YggA)
DKE46_012515	COG2871	sodium ion transport
DKE46_012535	COG4638	Rieske (2fe-2S)
DKE46_012540	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DKE46_012545	COG0633	Ferredoxin
DKE46_012545	COG0543	2 iron, 2 sulfur cluster binding
DKE46_012550	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_012580	COG0450	alkyl hydroperoxide reductase
DKE46_012600	COG3634	alkyl hydroperoxide reductase activity
DKE46_012620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKE46_012625	COG0625	glutathione transferase activity
DKE46_012685	COG1765	OsmC-like protein
DKE46_012725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DKE46_012735	COG0582	viral genome integration into host DNA
DKE46_012755	COG3293	Transposase
DKE46_012795	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DKE46_012800	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DKE46_012850	COG1598	PFAM Uncharacterised protein family UPF0150
DKE46_013005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKE46_013035	COG1741	Belongs to the pirin family
DKE46_013040	COG1309	transcriptional regulator
DKE46_013245	COG4948	Mandelate Racemase Muconate Lactonizing
DKE46_013260	COG0697	spore germination
DKE46_013365	COG2801	Transposase and inactivated derivatives
DKE46_013435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DKE46_013470	COG4174	ABC transporter (Permease)
DKE46_013615	COG3384	dioxygenase
DKE46_013630	COG2878	Part of a membrane complex involved in electron transport
DKE46_013635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKE46_013665	COG0742	ribosomal rna small subunit methyltransferase
DKE46_013680	COG0830	nickel cation binding
DKE46_013715	COG3015	lipoprotein NlpE involved in copper resistance
DKE46_013785	COG1773	rubredoxin
DKE46_013800	COG0583	DNA-binding transcription factor activity
DKE46_013900	COG0306	phosphate transporter
DKE46_013925	COG2271	Major facilitator Superfamily
DKE46_013955	COG2223	nitrite transmembrane transporter activity
DKE46_013960	COG2207	Transcriptional regulator
DKE46_013960	COG0662	Cupin 2, conserved barrel domain protein
DKE46_013965	COG2066	Belongs to the glutaminase family
DKE46_013970	COG0242	peptide deformylase activity
DKE46_014005	COG2267	carboxylic ester hydrolase activity
DKE46_014015	COG2271	Major facilitator Superfamily
DKE46_014070	COG1024	Enoyl-CoA hydratase
DKE46_014080	COG1215	transferase activity, transferring glycosyl groups
DKE46_014095	COG4681	YaeQ
DKE46_014115	COG1607	acyl-coa hydrolase
DKE46_014135	COG1309	transcriptional regulator
DKE46_014310	COG2814	Major facilitator Superfamily
DKE46_014320	COG2050	protein possibly involved in aromatic compounds catabolism
DKE46_014390	COG0735	belongs to the Fur family
DKE46_014420	COG0121	glutamine amidotransferase
DKE46_014450	COG2885	chlorophyll binding
DKE46_014470	COG2894	cell division
DKE46_014495	COG0492	ferredoxin-NADP+ reductase activity
DKE46_014510	COG0456	acetyltransferase
DKE46_014525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKE46_014530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DKE46_014605	COG0473	3-isopropylmalate dehydrogenase activity
DKE46_014610	COG0583	DNA-binding transcription factor activity
DKE46_014630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE46_014680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DKE46_014750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE46_014750	COG0351	phosphomethylpyrimidine kinase
DKE46_014750	COG0352	thiamine-phosphate diphosphorylase activity
DKE46_014755	COG1652	LysM domain
DKE46_014785	COG3101	peptidyl-lysine hydroxylation
DKE46_014790	COG0009	L-threonylcarbamoyladenylate synthase
DKE46_014795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKE46_014800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKE46_014815	COG4106	trans-aconitate 2-methyltransferase activity
DKE46_014840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DKE46_014845	COG2223	nitrite transmembrane transporter activity
DKE46_014865	COG1196	nuclear chromosome segregation
DKE46_014900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKE46_015020	COG0668	transmembrane transport
DKE46_015060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DKE46_015065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DKE46_015135	COG0745	RESPONSE REGULATOR receiver
DKE46_015150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKE46_015210	COG0438	transferase activity, transferring glycosyl groups
DKE46_015285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE46_015335	COG0583	DNA-binding transcription factor activity
DKE46_015355	COG0583	DNA-binding transcription factor activity
DKE46_015425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DKE46_015465	COG0561	phosphatase activity
DKE46_015470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKE46_015480	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DKE46_015495	COG1214	PFAM Peptidase M22, glycoprotease
DKE46_015560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DKE46_015565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DKE46_015570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKE46_015645	COG1764	response to oxidative stress
DKE46_015740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKE46_015745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKE46_015765	COG0625	glutathione transferase activity
DKE46_015795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE46_015865	COG1024	Enoyl-CoA hydratase
DKE46_015870	COG2084	Dehydrogenase
DKE46_015890	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DKE46_015895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DKE46_015955	COG0492	ferredoxin-NADP+ reductase activity
DKE46_015960	COG0431	NADPH-dependent FMN reductase
DKE46_015965	COG0798	PFAM Bile acid sodium symporter
DKE46_015975	COG0640	Transcriptional regulator
DKE46_016130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKE46_016210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DKE46_016215	COG0440	acetolactate synthase activity
DKE46_016220	COG0028	Belongs to the TPP enzyme family
DKE46_016240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE46_016275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DKE46_016290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DKE46_016330	COG1426	Protein conserved in bacteria
DKE46_016365	COG0793	Belongs to the peptidase S41A family
DKE46_016380	COG2267	carboxylic ester hydrolase activity
DKE46_016390	COG1012	belongs to the aldehyde dehydrogenase family
DKE46_016395	COG3265	gluconokinase activity
DKE46_016420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DKE46_016430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DKE46_016430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DKE46_016480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKE46_016480	COG2813	Specifically methylates the guanine in position
DKE46_016580	COG0788	formyltetrahydrofolate deformylase activity
DKE46_016600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKE46_016635	COG0724	RNA recognition motif
DKE46_016665	COG1733	regulation of RNA biosynthetic process
DKE46_016670	COG0604	alcohol dehydrogenase
DKE46_016675	COG2900	Belongs to the SlyX family
DKE46_016695	COG1560	Kdo2-lipid A biosynthetic process
DKE46_016825	COG0583	DNA-binding transcription factor activity
DKE46_016840	COG0625	glutathione transferase activity
DKE46_016850	COG0546	phosphoglycolate phosphatase activity
DKE46_016885	COG0583	DNA-binding transcription factor activity
DKE46_016955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DKE46_016960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE46_016975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKE46_017000	COG4535	Mg2 and Co2 transporter CorC
DKE46_017010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE46_017040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKE46_017055	COG0789	Transcriptional regulator
DKE46_017060	COG0598	Magnesium transport protein CorA
DKE46_017065	COG1185	polyribonucleotide nucleotidyltransferase activity
DKE46_017080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKE46_017110	COG2226	methyltransferase
DKE46_017175	COG2212	antiporter activity
DKE46_017185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKE46_017255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKE46_017315	COG2169	Transcriptional regulator
DKE46_017315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKE46_017320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKE46_017420	COG2056	Na+-H+ antiporter family
DKE46_017520	COG0546	phosphoglycolate phosphatase activity
DKE46_017570	COG0181	hydroxymethylbilane synthase activity
DKE46_017610	COG0697	spore germination
DKE46_017635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DKE46_017640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE46_017700	COG2197	response regulator
DKE46_017780	COG0347	Belongs to the P(II) protein family
DKE46_017795	COG0431	NADPH-dependent FMN reductase
DKE46_017810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE46_017860	COG2860	membrane
DKE46_017930	COG0655	NAD(P)H dehydrogenase (quinone) activity
DKE46_017945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE46_018020	COG0697	spore germination
DKE46_018055	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DKE46_018105	COG1121	(ABC) transporter
DKE46_018110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKE46_018115	COG1280	lysine exporter protein (LysE YggA)
DKE46_018170	COG0519	Catalyzes the synthesis of GMP from XMP
DKE46_018170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE46_018180	COG2259	Doxx family
DKE46_018185	COG0586	Pfam SNARE associated Golgi protein
DKE46_018210	COG0271	Belongs to the BolA IbaG family
DKE46_018255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKE46_018255	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DKE46_018255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DKE46_018255	COG3321	synthase
DKE46_018270	COG2197	response regulator
DKE46_018280	COG3916	Acyl-homoserine-lactone synthase
DKE46_018300	COG1113	amino acid transport
DKE46_018305	COG0697	spore germination
DKE46_018315	COG1024	Enoyl-CoA hydratase
DKE46_018320	COG1024	Enoyl-CoA hydratase
DKE46_018400	COG0564	pseudouridine synthase activity
DKE46_018435	COG1051	belongs to the nudix hydrolase family
DKE46_018470	COG1802	Transcriptional regulator
DKE46_018480	COG1448	Aminotransferase
DKE46_018495	COG2186	Transcriptional regulator
DKE46_018525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DKE46_018560	COG1091	dTDP-4-dehydrorhamnose reductase activity
DKE46_018590	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DKE46_018625	COG3023	N-Acetylmuramoyl-L-alanine amidase
DKE46_018680	COG0546	phosphoglycolate phosphatase activity
DKE46_018685	COG1028	Short-chain dehydrogenase reductase Sdr
DKE46_018715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE46_018720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKE46_018760	COG1047	Peptidyl-prolyl cis-trans
DKE46_018800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DKE46_018855	COG2951	lytic endotransglycosylase activity
DKE46_018860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DKE46_018875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKE46_018890	COG0861	Integral membrane protein TerC family
DKE46_018960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DKE46_019090	COG2009	succinate dehydrogenase
DKE46_019110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DKE46_019160	COG0625	glutathione transferase activity
DKE46_019165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKE46_019190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE46_019330	COG2826	transposase and inactivated derivatives, IS30 family
DKE46_019495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DKE46_019545	COG1525	nuclease
DKE46_019740	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKE46_019825	COG0745	RESPONSE REGULATOR receiver
DKE46_019860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DKE46_019865	COG3316	Transposase and inactivated derivatives
DKE46_019905	COG3316	Transposase and inactivated derivatives
DKE46_019970	COG3173	Aminoglycoside phosphotransferase
DKE46_019975	COG3316	Transposase and inactivated derivatives
DKE46_019995	COG3316	Transposase and inactivated derivatives
DKE46_020355	COG1192	Involved in chromosome partitioning
DKE46_020425	COG1192	Involved in chromosome partitioning
DKE46_020460	COG0604	alcohol dehydrogenase
DKE46_020595	COG3321	synthase
DKE46_020595	COG0604	alcohol dehydrogenase