locus-tag	class	description
G8E09_00010	COG0592	DNA-directed DNA polymerase activity
G8E09_00020	COG0187	DNA topoisomerase II activity
G8E09_00035	COG0488	(ABC) transporter
G8E09_00060	COG0596	Alpha beta hydrolase
G8E09_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G8E09_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G8E09_00100	COG0625	glutathione transferase activity
G8E09_00110	COG0733	neurotransmitter:sodium symporter activity
G8E09_00150	COG2233	PERMEase
G8E09_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E09_00200	COG2814	Major facilitator Superfamily
G8E09_00205	COG0656	L-ascorbic acid biosynthetic process
G8E09_00210	COG0583	DNA-binding transcription factor activity
G8E09_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E09_00230	COG1064	alcohol dehydrogenase
G8E09_00235	COG2818	Glycosylase
G8E09_00250	COG1194	a g-specific adenine glycosylase
G8E09_00265	COG5487	UPF0391 membrane protein
G8E09_00270	COG2983	Belongs to the UPF0260 family
G8E09_00275	COG2133	pyrroloquinoline quinone binding
G8E09_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G8E09_00285	COG2116	formate transmembrane transporter activity
G8E09_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G8E09_00310	COG1335	isochorismatase
G8E09_00315	COG0385	Bile acid
G8E09_00320	COG0534	Mate efflux family protein
G8E09_00325	COG1683	Conserved Protein
G8E09_00340	COG0346	lactoylglutathione lyase activity
G8E09_00345	COG0625	glutathione transferase activity
G8E09_00355	COG1113	amino acid transport
G8E09_00365	COG0523	cobalamin synthesis protein
G8E09_00375	COG2188	Transcriptional regulator
G8E09_00405	COG0010	Belongs to the arginase family
G8E09_00415	COG0546	phosphoglycolate phosphatase activity
G8E09_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G8E09_00425	COG1280	lysine exporter protein (LysE YggA)
G8E09_00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G8E09_00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G8E09_00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G8E09_00555	COG0534	Mate efflux family protein
G8E09_00560	COG0436	Aminotransferase
G8E09_00565	COG2733	membrane
G8E09_00580	COG2918	glutathione biosynthetic process
G8E09_00590	COG3501	Rhs element vgr protein
G8E09_00625	COG3150	esterase
G8E09_00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G8E09_00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_00655	COG2233	PERMEase
G8E09_00660	COG2351	hydroxyisourate hydrolase activity
G8E09_00695	COG3706	GGDEF domain
G8E09_00710	COG1393	Belongs to the ArsC family
G8E09_00715	COG0708	Exodeoxyribonuclease III
G8E09_00745	COG0189	ligase activity
G8E09_00765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G8E09_00775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G8E09_00790	COG4942	peptidase
G8E09_00800	COG0508	dehydrogenase complex catalyzes the overall conversion of
G8E09_00810	COG2119	membrane
G8E09_00815	COG4774	siderophore transport
G8E09_00820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E09_00820	COG0426	domain, Protein
G8E09_00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G8E09_00860	COG1902	pentaerythritol trinitrate reductase activity
G8E09_00865	COG1519	Transferase
G8E09_00870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G8E09_00875	COG0668	transmembrane transport
G8E09_00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G8E09_00890	COG1335	isochorismatase
G8E09_00895	COG1522	sequence-specific DNA binding
G8E09_00920	COG0784	Response regulator, receiver
G8E09_00920	COG2198	Histidine kinase
G8E09_00920	COG2205	protein histidine kinase activity
G8E09_00925	COG3162	membrane
G8E09_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G8E09_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G8E09_00950	COG3706	GGDEF domain
G8E09_00960	COG1309	transcriptional regulator
G8E09_00980	COG0300	oxidoreductase activity
G8E09_00985	COG0789	Transcriptional regulator
G8E09_00990	COG0352	thiamine-phosphate diphosphorylase activity
G8E09_00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G8E09_00990	COG0351	phosphomethylpyrimidine kinase
G8E09_01000	COG2814	Major facilitator Superfamily
G8E09_01035	COG1002	Type II restriction enzyme, methylase subunits
G8E09_01045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G8E09_01055	COG1061	Type III restriction enzyme res subunit
G8E09_01060	COG1002	Type II restriction enzyme, methylase subunits
G8E09_01070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G8E09_01090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G8E09_01095	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_01105	COG1335	isochorismatase
G8E09_01145	COG2814	Major facilitator Superfamily
G8E09_01150	COG0583	DNA-binding transcription factor activity
G8E09_01175	COG0667	Aldo Keto reductase
G8E09_01190	COG1309	transcriptional regulator
G8E09_01215	COG1733	regulation of RNA biosynthetic process
G8E09_01220	COG2249	NAD(P)H dehydrogenase (quinone) activity
G8E09_01240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G8E09_01245	COG2207	Transcriptional regulator
G8E09_01305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G8E09_01320	COG2329	Antibiotic biosynthesis monooxygenase
G8E09_01335	COG1132	(ABC) transporter
G8E09_01345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G8E09_01355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G8E09_01385	COG0427	acetyl-CoA hydrolase
G8E09_01395	COG2205	protein histidine kinase activity
G8E09_01400	COG0745	RESPONSE REGULATOR receiver
G8E09_01410	COG0659	secondary active sulfate transmembrane transporter activity
G8E09_01415	COG4221	oxidoreductase activity
G8E09_01425	COG2814	Major facilitator Superfamily
G8E09_01435	COG2873	o-acetylhomoserine
G8E09_01440	COG0488	(ABC) transporter
G8E09_01520	COG0833	amino acid
G8E09_01565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G8E09_01570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G8E09_01585	COG2226	methyltransferase
G8E09_01635	COG0067	glutamate synthase
G8E09_01635	COG0069	glutamate synthase activity
G8E09_01635	COG0070	glutamate synthase
G8E09_01640	COG0493	'glutamate synthase
G8E09_01650	COG1704	LemA family
G8E09_01655	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G8E09_01675	COG3307	-O-antigen
G8E09_01695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G8E09_01710	COG0194	GDP metabolic process
G8E09_01760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G8E09_01770	COG0335	large ribosomal subunit rRNA binding
G8E09_01780	COG5380	lipid catabolic process
G8E09_01785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G8E09_01810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G8E09_01815	COG0277	FAD linked oxidase domain protein
G8E09_01835	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G8E09_01840	COG2249	NAD(P)H dehydrogenase (quinone) activity
G8E09_01855	COG1289	transmembrane transporter activity
G8E09_01865	COG0628	permease
G8E09_01870	COG1192	Involved in chromosome partitioning
G8E09_01900	COG0833	amino acid
G8E09_01905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G8E09_01910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G8E09_01920	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_01960	COG0583	DNA-binding transcription factor activity
G8E09_01985	COG0752	glycyl-tRNA synthetase alpha subunit
G8E09_02010	COG0517	IMP dehydrogenase activity
G8E09_02010	COG0617	tRNA 3'-terminal CCA addition
G8E09_02010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G8E09_02015	COG1983	PspC domain protein
G8E09_02025	COG1960	acyl-CoA dehydrogenase activity
G8E09_02040	COG0408	coproporphyrinogen oxidase activity
G8E09_02060	COG0513	Belongs to the DEAD box helicase family
G8E09_02070	COG1127	ABC transporter
G8E09_02075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G8E09_02085	COG2854	intermembrane phospholipid transfer
G8E09_02095	COG0598	Magnesium transport protein CorA
G8E09_02105	COG0494	nUDIX hydrolase
G8E09_02110	COG1040	competence protein
G8E09_02115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G8E09_02135	COG1946	Acyl-CoA thioesterase
G8E09_02140	COG1301	dicarboxylic acid transport
G8E09_02155	COG1959	2 iron, 2 sulfur cluster binding
G8E09_02160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E09_02160	COG1017	nitric oxide dioxygenase activity
G8E09_02170	COG0433	COG0433 Predicted ATPase
G8E09_02175	COG0626	cystathionine gamma-synthase activity
G8E09_02190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G8E09_02195	COG0088	Forms part of the polypeptide exit tunnel
G8E09_02330	COG1960	acyl-CoA dehydrogenase activity
G8E09_02335	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G8E09_02365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G8E09_02370	COG0339	signal peptide processing
G8E09_02375	COG0557	exoribonuclease II activity
G8E09_02425	COG0179	Fumarylacetoacetate (FAA) hydrolase
G8E09_02430	COG1295	ribonuclease BN
G8E09_02465	COG1702	phosphate starvation-inducible protein PhoH
G8E09_02475	COG0739	heme binding
G8E09_02475	COG0741	lytic transglycosylase activity
G8E09_02475	COG1196	nuclear chromosome segregation
G8E09_02505	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G8E09_02510	COG1183	phosphatidylcholine synthase activity
G8E09_02555	COG1960	acyl-CoA dehydrogenase activity
G8E09_02560	COG1309	transcriptional regulator
G8E09_02575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G8E09_02580	COG1960	acyl-CoA dehydrogenase activity
G8E09_02620	COG2969	positive regulation of protein catabolic process
G8E09_02630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G8E09_02635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G8E09_02640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G8E09_02645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G8E09_02650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G8E09_02670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G8E09_02680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G8E09_02685	COG1408	metallophosphoesterase
G8E09_02690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G8E09_02690	COG2885	chlorophyll binding
G8E09_02695	COG2199	diguanylate cyclase activity
G8E09_02765	COG1607	acyl-coa hydrolase
G8E09_02800	COG2350	Protein conserved in bacteria
G8E09_02815	COG3781	membrane
G8E09_02825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G8E09_02830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G8E09_02840	COG1862	Preprotein translocase
G8E09_02860	COG0784	Response regulator, receiver
G8E09_02860	COG2205	protein histidine kinase activity
G8E09_02860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E09_02860	COG2198	Histidine kinase
G8E09_02865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G8E09_02885	COG0726	polysaccharide deacetylase
G8E09_02890	COG0463	Glycosyl transferase, family 2
G8E09_02895	COG0438	transferase activity, transferring glycosyl groups
G8E09_02905	COG0438	transferase activity, transferring glycosyl groups
G8E09_02920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G8E09_02940	COG1216	Glycosyl transferase, family 2
G8E09_02985	COG1960	acyl-CoA dehydrogenase activity
G8E09_02990	COG1960	acyl-CoA dehydrogenase activity
G8E09_03000	COG2205	protein histidine kinase activity
G8E09_03005	COG0745	RESPONSE REGULATOR receiver
G8E09_03015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G8E09_03035	COG2096	Adenosyltransferase
G8E09_03040	COG4206	TonB-dependent receptor
G8E09_03085	COG0285	dihydrofolate synthase activity
G8E09_03110	COG0450	alkyl hydroperoxide reductase
G8E09_03125	COG0477	Major facilitator Superfamily
G8E09_03130	COG1272	protein, Hemolysin III
G8E09_03140	COG2153	protein acetylation
G8E09_03160	COG0183	Belongs to the thiolase family
G8E09_03165	COG2207	Transcriptional regulator
G8E09_03185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E09_03205	COG0183	Belongs to the thiolase family
G8E09_03215	COG2885	chlorophyll binding
G8E09_03215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G8E09_03225	COG1690	Belongs to the RtcB family
G8E09_03230	COG0833	amino acid
G8E09_03240	COG2233	PERMEase
G8E09_03275	COG2094	Belongs to the DNA glycosylase MPG family
G8E09_03280	COG4772	TonB-dependent receptor
G8E09_03285	COG1902	pentaerythritol trinitrate reductase activity
G8E09_03290	COG0679	Auxin Efflux Carrier
G8E09_03300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G8E09_03305	COG0354	folic acid binding
G8E09_03320	COG3189	MarR family transcriptional regulator
G8E09_03325	COG2824	Alkylphosphonate utilization operon protein PhnA
G8E09_03330	COG3422	double-strand break repair
G8E09_03370	COG0840	transmembrane signaling receptor activity
G8E09_03395	COG5510	response to toxic substance
G8E09_03405	COG2832	Protein of unknown function (DUF454)
G8E09_03410	COG1376	ErfK ybiS ycfS ynhG family protein
G8E09_03450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G8E09_03460	COG1289	transmembrane transporter activity
G8E09_03465	COG2814	Major facilitator Superfamily
G8E09_03485	COG1115	amino acid carrier protein
G8E09_03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
G8E09_03495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G8E09_03500	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G8E09_03505	COG3590	peptidase
G8E09_03530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G8E09_03540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G8E09_03545	COG1077	Cell shape determining protein MreB Mrl
G8E09_03550	COG1792	Involved in formation and maintenance of cell shape
G8E09_03555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G8E09_03560	COG0424	maF-like protein
G8E09_03565	COG1530	ribonuclease E activity
G8E09_03575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G8E09_03595	COG2249	NAD(P)H dehydrogenase (quinone) activity
G8E09_03620	COG2207	Transcriptional regulator
G8E09_03645	COG1113	amino acid transport
G8E09_03650	COG2828	Protein conserved in bacteria
G8E09_03655	COG0142	geranyltranstransferase activity
G8E09_03660	COG2315	Protein conserved in bacteria
G8E09_03675	COG1752	Esterase of the alpha-beta hydrolase superfamily
G8E09_03700	COG2194	sulfuric ester hydrolase activity
G8E09_03705	COG0745	RESPONSE REGULATOR receiver
G8E09_03710	COG0642	Histidine kinase
G8E09_03725	COG0004	ammonium transporteR
G8E09_03730	COG0583	DNA-binding transcription factor activity
G8E09_03750	COG0525	valine-tRNA ligase activity
G8E09_03760	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_03770	COG0393	Putative heavy-metal-binding
G8E09_03775	COG0393	Putative heavy-metal-binding
G8E09_03780	COG1538	Outer membrane efflux protein
G8E09_03790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E09_03795	COG0671	phosphoesterase, PA-phosphatase related
G8E09_03820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G8E09_03835	COG1648	precorrin-2 dehydrogenase activity
G8E09_03835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G8E09_03840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G8E09_03855	COG0531	amino acid
G8E09_03870	COG0321	lipoyl(octanoyl) transferase activity
G8E09_03875	COG2921	Belongs to the UPF0250 family
G8E09_03915	COG2009	succinate dehydrogenase
G8E09_03920	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G8E09_03925	COG1053	succinate dehydrogenase
G8E09_03930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G8E09_03955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8E09_03975	COG2354	Protein conserved in bacteria
G8E09_03980	COG2321	neutral zinc metallopeptidase
G8E09_04000	COG2843	Capsule synthesis protein
G8E09_04020	COG0589	response to stress
G8E09_04030	COG0251	oxidation-reduction process
G8E09_04035	COG1309	transcriptional regulator
G8E09_04050	COG0505	Belongs to the CarA family
G8E09_04080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G8E09_04085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G8E09_04135	COG0477	Major facilitator Superfamily
G8E09_04140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G8E09_04155	COG1597	lipid kinase activity
G8E09_04160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G8E09_04185	COG0584	glycerophosphoryl diester phosphodiesterase
G8E09_04205	COG0741	lytic transglycosylase activity
G8E09_04230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G8E09_04280	COG0778	Nitroreductase
G8E09_04295	COG1929	Belongs to the glycerate kinase type-1 family
G8E09_04300	COG0243	molybdopterin cofactor binding
G8E09_04305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G8E09_04335	COG1115	amino acid carrier protein
G8E09_04340	COG1113	amino acid transport
G8E09_04350	COG0019	diaminopimelate decarboxylase activity
G8E09_04370	COG1280	lysine exporter protein (LysE YggA)
G8E09_04375	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G8E09_04405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E09_04435	COG4591	ABC-type transport system involved in lipoprotein release permease component
G8E09_04440	COG1136	(ABC) transporter
G8E09_04445	COG0658	competence protein
G8E09_04445	COG2333	competence protein COMEC
G8E09_04455	COG0616	signal peptide processing
G8E09_04455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G8E09_04460	COG0596	Alpha beta hydrolase
G8E09_04465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G8E09_04475	COG0628	permease
G8E09_04510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8E09_04530	COG0823	Involved in the tonB-independent uptake of proteins
G8E09_04550	COG0824	Thioesterase
G8E09_04555	COG1473	amidohydrolase
G8E09_04575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G8E09_04575	COG0047	phosphoribosylformylglycinamidine synthase activity
G8E09_04580	COG2814	Major facilitator Superfamily
G8E09_04585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G8E09_04590	COG1024	Enoyl-CoA hydratase
G8E09_04595	COG1051	belongs to the nudix hydrolase family
G8E09_04595	COG1056	cytidyltransferase-related domain
G8E09_04600	COG0583	DNA-binding transcription factor activity
G8E09_04605	COG0625	glutathione transferase activity
G8E09_04610	COG1942	4-Oxalocrotonate Tautomerase
G8E09_04630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8E09_04645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G8E09_04660	COG4625	pathogenesis
G8E09_04665	COG0583	DNA-binding transcription factor activity
G8E09_04670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G8E09_04675	COG4208	sulfate ABC transporter
G8E09_04680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G8E09_04690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G8E09_04695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G8E09_04700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G8E09_04720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G8E09_04730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G8E09_04735	COG0481	GTPase activity
G8E09_04740	COG0681	Belongs to the peptidase S26 family
G8E09_04750	COG0571	ribonuclease III activity
G8E09_04755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G8E09_04765	COG1381	Involved in DNA repair and RecF pathway recombination
G8E09_04770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G8E09_04780	COG4221	oxidoreductase activity
G8E09_04810	COG0436	Aminotransferase
G8E09_04830	COG0556	nucleotide-excision repair
G8E09_04840	COG2962	Rard protein
G8E09_04885	COG2070	2-Nitropropane dioxygenase
G8E09_04900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G8E09_04915	COG1215	transferase activity, transferring glycosyl groups
G8E09_04930	COG0415	Belongs to the DNA photolyase family
G8E09_04940	COG1252	NADH dehydrogenase
G8E09_04945	COG1686	Belongs to the peptidase S11 family
G8E09_04960	COG1187	pseudouridine synthase activity
G8E09_04975	COG0477	Major facilitator Superfamily
G8E09_04980	COG0583	DNA-binding transcription factor activity
G8E09_04995	COG0612	Peptidase, M16
G8E09_05020	COG0352	thiamine-phosphate diphosphorylase activity
G8E09_05055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E09_05070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G8E09_05075	COG0076	glutamate decarboxylase activity
G8E09_05085	COG1522	sequence-specific DNA binding
G8E09_05090	COG3961	Belongs to the TPP enzyme family
G8E09_05095	COG1113	amino acid transport
G8E09_05100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G8E09_05105	COG0573	inorganic phosphate transmembrane transporter activity
G8E09_05115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G8E09_05120	COG0616	signal peptide processing
G8E09_05160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G8E09_05165	COG1686	Belongs to the peptidase S11 family
G8E09_05190	COG0583	DNA-binding transcription factor activity
G8E09_05195	COG1067	ATP-dependent peptidase activity
G8E09_05200	COG2211	Major facilitator Superfamily
G8E09_05235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G8E09_05240	COG1966	Carbon starvation protein
G8E09_05245	COG2879	small protein
G8E09_05290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G8E09_05295	COG1741	Belongs to the pirin family
G8E09_05310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G8E09_05315	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G8E09_05320	COG4605	iron ion homeostasis
G8E09_05325	COG4604	ABC transporter, ATP-binding protein
G8E09_05330	COG4607	ABC-type enterochelin transport system periplasmic component
G8E09_05335	COG4774	siderophore transport
G8E09_05345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G8E09_05350	COG1021	2,3-dihydroxybenzoate-AMP ligase
G8E09_05355	COG1535	isochorismatase
G8E09_05355	COG3433	isochorismatase activity
G8E09_05375	COG5265	(ABC) transporter
G8E09_05380	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G8E09_05390	COG1169	isochorismate synthase
G8E09_05405	COG3739	integral membrane protein
G8E09_05435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G8E09_05445	COG2840	Smr protein MutS2
G8E09_05460	COG0512	Glutamine amidotransferase of anthranilate synthase
G8E09_05475	COG3104	oligopeptide transport
G8E09_05480	COG0174	glutamine synthetase
G8E09_05490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G8E09_05525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G8E09_05530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G8E09_05535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G8E09_05555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G8E09_05560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G8E09_05565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G8E09_05580	COG1960	acyl-CoA dehydrogenase activity
G8E09_05585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G8E09_05590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8E09_05600	COG2223	nitrite transmembrane transporter activity
G8E09_05610	COG0024	Methionine aminopeptidase
G8E09_05615	COG0052	Belongs to the universal ribosomal protein uS2 family
G8E09_05630	COG2207	Transcriptional regulator
G8E09_05655	COG2951	lytic endotransglycosylase activity
G8E09_05660	COG0772	Belongs to the SEDS family
G8E09_05675	COG0842	Transport permease protein
G8E09_05680	COG1131	(ABC) transporter
G8E09_05685	COG0582	viral genome integration into host DNA
G8E09_05805	COG5410	chromosome segregation
G8E09_05930	COG0739	heme binding
G8E09_06060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E09_06070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E09_06075	COG4215	(ABC) transporter
G8E09_06080	COG4160	amino acid transport
G8E09_06085	COG4598	ABC transporter
G8E09_06095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G8E09_06105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E09_06110	COG0384	phenazine biosynthesis protein PhzF
G8E09_06120	COG1720	tRNA m6t6A37 methyltransferase activity
G8E09_06140	COG0745	RESPONSE REGULATOR receiver
G8E09_06145	COG0642	Histidine kinase
G8E09_06155	COG0494	nUDIX hydrolase
G8E09_06165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G8E09_06170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G8E09_06175	COG3139	Protein of unknown function (DUF1315)
G8E09_06180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G8E09_06185	COG1301	dicarboxylic acid transport
G8E09_06190	COG1960	acyl-CoA dehydrogenase activity
G8E09_06210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G8E09_06220	COG2195	Cleaves the N-terminal amino acid of tripeptides
G8E09_06225	COG1234	tRNA 3'-trailer cleavage
G8E09_06250	COG2363	Small membrane protein
G8E09_06270	COG0513	Belongs to the DEAD box helicase family
G8E09_06280	COG0778	Nitroreductase
G8E09_06310	COG1286	toxin biosynthetic process
G8E09_06335	COG4783	chaperone-mediated protein folding
G8E09_06340	COG1610	YqeY-like protein
G8E09_06370	COG0515	serine threonine protein kinase
G8E09_06370	COG2815	serine threonine protein kinase
G8E09_06395	COG1278	Cold shock
G8E09_06410	COG3243	poly(R)-hydroxyalkanoic acid synthase
G8E09_06415	COG0786	glutamate:sodium symporter activity
G8E09_06420	COG0475	glutathione-regulated potassium exporter activity
G8E09_06420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G8E09_06430	COG1309	transcriptional regulator
G8E09_06440	COG2985	domain, Protein
G8E09_06455	COG0583	DNA-binding transcription factor activity
G8E09_06465	COG2995	paraquat-inducible protein a
G8E09_06470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G8E09_06470	COG3008	intermembrane lipid transfer
G8E09_06480	COG2351	hydroxyisourate hydrolase activity
G8E09_06520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G8E09_06530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G8E09_06535	COG0642	Histidine kinase
G8E09_06540	COG0745	RESPONSE REGULATOR receiver
G8E09_06560	COG1794	racemase activity, acting on amino acids and derivatives
G8E09_06580	COG2814	Major facilitator Superfamily
G8E09_06605	COG1301	dicarboxylic acid transport
G8E09_06615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G8E09_06620	COG2011	ABC-type metal ion transport system permease component
G8E09_06625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G8E09_06635	COG0151	Belongs to the GarS family
G8E09_06645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G8E09_06675	COG2308	Evidence 4 Homologs of previously reported genes of
G8E09_06685	COG1305	Transglutaminase-like
G8E09_06695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G8E09_06700	COG0305	Participates in initiation and elongation during chromosome replication
G8E09_06725	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G8E09_06730	COG1845	cytochrome c oxidase, subunit III
G8E09_06735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G8E09_06765	COG1649	PFAM Uncharacterised BCR, COG1649
G8E09_06765	COG0726	polysaccharide deacetylase
G8E09_06770	COG1215	transferase activity, transferring glycosyl groups
G8E09_06775	COG3658	cytochrome
G8E09_06785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E09_06800	COG0583	DNA-binding transcription factor activity
G8E09_06815	COG2890	protein-(glutamine-N5) methyltransferase activity
G8E09_06820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E09_06825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E09_06840	COG1960	acyl-CoA dehydrogenase activity
G8E09_06845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E09_06860	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G8E09_06870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G8E09_06875	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G8E09_06885	COG2205	protein histidine kinase activity
G8E09_06890	COG0745	RESPONSE REGULATOR receiver
G8E09_06895	COG0174	glutamine synthetase
G8E09_06910	COG0477	Major facilitator Superfamily
G8E09_06915	COG0729	surface antigen
G8E09_06945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G8E09_06950	COG2814	Major facilitator Superfamily
G8E09_06965	COG0583	DNA-binding transcription factor activity
G8E09_06980	COG1187	pseudouridine synthase activity
G8E09_07000	COG0802	atpase or kinase
G8E09_07005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G8E09_07015	COG1923	regulation of RNA biosynthetic process
G8E09_07020	COG0697	spore germination
G8E09_07030	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8E09_07040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G8E09_07045	COG0519	Catalyzes the synthesis of GMP from XMP
G8E09_07045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G8E09_07050	COG4302	ethanolamine ammonia-lyase activity
G8E09_07055	COG4303	Ethanolamine ammonia lyase large subunit
G8E09_07060	COG0531	amino acid
G8E09_07080	COG1454	alcohol dehydrogenase
G8E09_07085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G8E09_07110	COG0308	aminopeptidase N
G8E09_07150	COG1605	Chorismate mutase
G8E09_07190	COG3772	lysozyme
G8E09_07215	COG0583	DNA-binding transcription factor activity
G8E09_07250	COG0488	(ABC) transporter
G8E09_07255	COG0589	response to stress
G8E09_07275	COG3135	benzoate transporter
G8E09_07280	COG1522	sequence-specific DNA binding
G8E09_07290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G8E09_07295	COG0583	DNA-binding transcription factor activity
G8E09_07305	COG0183	Belongs to the thiolase family
G8E09_07310	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_07315	COG2030	dehydratase
G8E09_07345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G8E09_07355	COG0824	Thioesterase
G8E09_07360	COG1454	alcohol dehydrogenase
G8E09_07385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G8E09_07415	COG0069	glutamate synthase activity
G8E09_07565	COG5410	chromosome segregation
G8E09_07765	COG2814	Major facilitator Superfamily
G8E09_07780	COG0511	ligase activity, forming carbon-carbon bonds
G8E09_07805	COG4264	IucA IucC family
G8E09_07815	COG4264	IucA IucC family
G8E09_07820	COG2423	ornithine cyclodeaminase activity
G8E09_07825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G8E09_07835	COG1116	anion transmembrane transporter activity
G8E09_07835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E09_07850	COG2146	nitrite reductase [NAD(P)H] activity
G8E09_07850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E09_07855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E09_07860	COG0243	molybdopterin cofactor binding
G8E09_07870	COG0243	molybdopterin cofactor binding
G8E09_07875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G8E09_07890	COG0521	Mo-molybdopterin cofactor biosynthetic process
G8E09_07890	COG0315	cyclic pyranopterin monophosphate synthase activity
G8E09_07895	COG0303	'Molybdopterin
G8E09_07905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E09_07910	COG0697	spore germination
G8E09_07935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G8E09_07950	COG0596	Alpha beta hydrolase
G8E09_08000	COG2204	response regulator
G8E09_08005	COG3852	Histidine kinase
G8E09_08030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G8E09_08035	COG0575	Belongs to the CDS family
G8E09_08050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E09_08070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8E09_08085	COG2137	regulation of response to DNA damage stimulus
G8E09_08095	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G8E09_08100	COG1011	Hydrolase
G8E09_08115	COG1522	sequence-specific DNA binding
G8E09_08125	COG1113	amino acid transport
G8E09_08145	COG0659	secondary active sulfate transmembrane transporter activity
G8E09_08180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G8E09_08180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G8E09_08180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G8E09_08185	COG1105	Belongs to the carbohydrate kinase PfkB family
G8E09_08190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G8E09_08190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G8E09_08210	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G8E09_08220	COG0024	Methionine aminopeptidase
G8E09_08225	COG0583	DNA-binding transcription factor activity
G8E09_08235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G8E09_08240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G8E09_08245	COG0517	IMP dehydrogenase activity
G8E09_08245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G8E09_08270	COG0552	protein localization to endoplasmic reticulum
G8E09_08290	COG4890	Cyd operon protein YbgT
G8E09_08295	COG1294	oxidase, subunit
G8E09_08310	COG1585	Membrane protein implicated in regulation of membrane protease activity
G8E09_08320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G8E09_08325	COG4774	siderophore transport
G8E09_08340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G8E09_08345	COG0569	domain protein
G8E09_08350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G8E09_08380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G8E09_08385	COG0542	response to heat
G8E09_08395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G8E09_08410	COG0446	pyridine nucleotide-disulphide oxidoreductase
G8E09_08410	COG1902	pentaerythritol trinitrate reductase activity
G8E09_08450	COG0148	phosphopyruvate hydratase activity
G8E09_08455	COG2323	membrane
G8E09_08465	COG4773	Receptor
G8E09_08470	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G8E09_08480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G8E09_08485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G8E09_08490	COG0183	Belongs to the thiolase family
G8E09_08495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G8E09_08500	COG0596	Alpha beta hydrolase
G8E09_08505	COG2271	Major facilitator Superfamily
G8E09_08510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G8E09_08515	COG3485	protocatechuate 3,4-dioxygenase
G8E09_08520	COG3485	protocatechuate 3,4-dioxygenase
G8E09_08525	COG0710	3-dehydroquinate dehydratase activity
G8E09_08530	COG3420	alginic acid biosynthetic process
G8E09_08535	COG3659	wide pore channel activity
G8E09_08540	COG4993	Dehydrogenase
G8E09_08550	COG2391	methyltransferase activity
G8E09_08565	COG1414	Transcriptional regulator
G8E09_08570	COG0583	DNA-binding transcription factor activity
G8E09_08575	COG1960	acyl-CoA dehydrogenase activity
G8E09_08605	COG2814	Major facilitator Superfamily
G8E09_08615	COG0154	amidase activity
G8E09_08645	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_08655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E09_08665	COG3733	amine oxidase
G8E09_08680	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_08685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G8E09_08690	COG0183	Belongs to the thiolase family
G8E09_08695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G8E09_08700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G8E09_08710	COG4829	muconolactone delta-isomerase
G8E09_08715	COG4948	Mandelate Racemase Muconate Lactonizing
G8E09_08720	COG0583	DNA-binding transcription factor activity
G8E09_08730	COG2186	Transcriptional regulator
G8E09_08750	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_08760	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_08775	COG0753	catalase activity
G8E09_08795	COG3604	Transcriptional regulator
G8E09_08820	COG2144	transferase activity, transferring acyl groups
G8E09_08830	COG2072	flavoprotein involved in K transport
G8E09_08835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_08855	COG0277	FAD linked oxidase domain protein
G8E09_08875	COG2197	response regulator
G8E09_08880	COG2814	Major facilitator Superfamily
G8E09_08910	COG2267	carboxylic ester hydrolase activity
G8E09_08920	COG0402	S-adenosylhomocysteine deaminase activity
G8E09_08925	COG2814	Major facilitator Superfamily
G8E09_09025	COG3231	kanamycin kinase activity
G8E09_09040	COG1960	acyl-CoA dehydrogenase activity
G8E09_09045	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09050	COG3829	transcription factor binding
G8E09_09075	COG1846	Transcriptional regulator
G8E09_09080	COG0446	pyridine nucleotide-disulphide oxidoreductase
G8E09_09080	COG1902	pentaerythritol trinitrate reductase activity
G8E09_09120	COG1309	transcriptional regulator
G8E09_09125	COG0583	DNA-binding transcription factor activity
G8E09_09130	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09135	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09140	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09150	COG1960	acyl-CoA dehydrogenase activity
G8E09_09160	COG0318	PFAM AMP-dependent synthetase and ligase
G8E09_09170	COG1309	transcriptional regulator
G8E09_09200	COG0583	DNA-binding transcription factor activity
G8E09_09225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G8E09_09230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G8E09_09280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_09335	COG1120	ATPase activity
G8E09_09345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G8E09_09445	COG1073	alpha beta
G8E09_09465	COG4628	conserved protein (DUF2132)
G8E09_09475	COG2175	clavaminate synthase activity
G8E09_09480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G8E09_09495	COG0667	Aldo Keto reductase
G8E09_09500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E09_09515	COG2175	clavaminate synthase activity
G8E09_09545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E09_09550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E09_09555	COG4771	TonB-dependent receptor
G8E09_09585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E09_09590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E09_09595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E09_09600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E09_09615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G8E09_09620	COG0805	protein transport
G8E09_09630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E09_09650	COG1132	(ABC) transporter
G8E09_09655	COG1132	(ABC) transporter
G8E09_09675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G8E09_09680	COG0601	transmembrane transport
G8E09_09685	COG0747	negative chemotaxis
G8E09_09710	COG3539	Fimbrial protein
G8E09_09735	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G8E09_09765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G8E09_09775	COG2205	protein histidine kinase activity
G8E09_09780	COG0745	RESPONSE REGULATOR receiver
G8E09_09785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E09_09790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G8E09_09845	COG3433	isochorismatase activity
G8E09_09845	COG1535	isochorismatase
G8E09_09850	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G8E09_09860	COG4149	molybdate abc transporter
G8E09_09865	COG0725	ABC transporter, periplasmic molybdate-binding protein
G8E09_09875	COG4638	Rieske (2fe-2S)
G8E09_09880	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G8E09_09885	COG0543	2 iron, 2 sulfur cluster binding
G8E09_09885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E09_09900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E09_09910	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09930	COG2207	Transcriptional regulator
G8E09_09935	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_09940	COG2610	gluconate transmembrane transporter activity
G8E09_09960	COG0583	DNA-binding transcription factor activity
G8E09_09975	COG2031	fatty acid transporter
G8E09_09980	COG0183	Belongs to the thiolase family
G8E09_09985	COG0583	DNA-binding transcription factor activity
G8E09_09990	COG0583	DNA-binding transcription factor activity
G8E09_10005	COG1027	Aspartate ammonia-lyase
G8E09_10015	COG0477	Major facilitator Superfamily
G8E09_10025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G8E09_10030	COG1733	regulation of RNA biosynthetic process
G8E09_10035	COG3708	Transcriptional regulator
G8E09_10035	COG2207	Transcriptional regulator
G8E09_10050	COG0730	response to heat
G8E09_10060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G8E09_10060	COG3453	Protein conserved in bacteria
G8E09_10070	COG3781	membrane
G8E09_10075	COG1063	alcohol dehydrogenase
G8E09_10085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8E09_10090	COG0508	dehydrogenase complex catalyzes the overall conversion of
G8E09_10095	COG0022	dehydrogenase e1 component
G8E09_10100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G8E09_10105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G8E09_10120	COG3706	GGDEF domain
G8E09_10140	COG0133	tryptophan synthase activity
G8E09_10150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G8E09_10180	COG0583	DNA-binding transcription factor activity
G8E09_10185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G8E09_10195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G8E09_10255	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8E09_10260	COG4773	Receptor
G8E09_10285	COG0730	response to heat
G8E09_10290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G8E09_10310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G8E09_10335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G8E09_10350	COG1960	acyl-CoA dehydrogenase activity
G8E09_10355	COG1960	acyl-CoA dehydrogenase activity
G8E09_10360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G8E09_10365	COG2207	Transcriptional regulator
G8E09_10370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8E09_10375	COG0776	regulation of translation
G8E09_10400	COG0822	iron-sulfur transferase activity
G8E09_10405	COG0316	Belongs to the HesB IscA family
G8E09_10435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G8E09_10455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G8E09_10460	COG0702	epimerase
G8E09_10500	COG0601	transmembrane transport
G8E09_10505	COG0339	signal peptide processing
G8E09_10510	COG4166	transmembrane transport
G8E09_10555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G8E09_10560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G8E09_10575	COG2431	L-lysine efflux transmembrane transporter activity
G8E09_10590	COG0776	regulation of translation
G8E09_10655	COG0084	hydrolase, TatD family'
G8E09_10675	COG1663	tetraacyldisaccharide 4'-kinase activity
G8E09_10680	COG1132	(ABC) transporter
G8E09_10690	COG0811	peptide transport
G8E09_10695	COG1475	DNA binding
G8E09_10700	COG1192	Involved in chromosome partitioning
G8E09_10710	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G8E09_10715	COG3178	'Phosphotransferase
G8E09_10725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8E09_10750	COG0424	maF-like protein
G8E09_10755	COG2850	peptidyl-arginine hydroxylation
G8E09_10765	COG0640	Transcriptional regulator
G8E09_10775	COG3619	membrane
G8E09_10780	COG3122	Protein conserved in bacteria
G8E09_10785	COG1132	(ABC) transporter
G8E09_10805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G8E09_10810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G8E09_10820	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G8E09_10820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G8E09_10820	COG0506	proline dehydrogenase activity
G8E09_10825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G8E09_10840	COG3698	Phosphodiester glycosidase
G8E09_10850	COG2353	YceI-like domain
G8E09_10860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G8E09_10905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G8E09_10905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G8E09_10930	COG3539	Fimbrial protein
G8E09_10965	COG0583	DNA-binding transcription factor activity
G8E09_10970	COG0697	spore germination
G8E09_10980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G8E09_10990	COG0583	DNA-binding transcription factor activity
G8E09_11005	COG1309	transcriptional regulator
G8E09_11020	COG1522	sequence-specific DNA binding
G8E09_11030	COG1126	abc transporter atp-binding protein
G8E09_11035	COG0765	amino acid transport
G8E09_11040	COG0765	amino acid transport
G8E09_11070	COG1464	Belongs to the NlpA lipoprotein family
G8E09_11080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G8E09_11085	COG2011	ABC-type metal ion transport system permease component
G8E09_11090	COG0012	GTP binding
G8E09_11115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G8E09_11150	COG1917	Cupin 2, conserved barrel domain protein
G8E09_11150	COG2207	Transcriptional regulator
G8E09_11155	COG0386	Belongs to the glutathione peroxidase family
G8E09_11165	COG0436	Aminotransferase
G8E09_11170	COG1301	dicarboxylic acid transport
G8E09_11205	COG3634	alkyl hydroperoxide reductase activity
G8E09_11220	COG0583	DNA-binding transcription factor activity
G8E09_11225	COG0431	NADPH-dependent FMN reductase
G8E09_11230	COG0798	PFAM Bile acid sodium symporter
G8E09_11240	COG0640	Transcriptional regulator
G8E09_11255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G8E09_11265	COG0583	DNA-binding transcription factor activity
G8E09_11275	COG1953	Uracil, thiamine, allantoin
G8E09_11285	COG2175	clavaminate synthase activity
G8E09_11290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E09_11295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G8E09_11300	COG4521	taurine ABC transporter
G8E09_11310	COG0477	Major facilitator Superfamily
G8E09_11330	COG1271	oxidase subunit
G8E09_11335	COG1294	oxidase, subunit
G8E09_11345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E09_11365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G8E09_11385	COG3052	prosthetic group binding
G8E09_11390	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
G8E09_11400	COG0583	DNA-binding transcription factor activity
G8E09_11410	COG2814	Major facilitator Superfamily
G8E09_11430	COG1346	cytolysis
G8E09_11440	COG0583	DNA-binding transcription factor activity
G8E09_11445	COG0625	glutathione transferase activity
G8E09_11450	COG0625	glutathione transferase activity
G8E09_11455	COG0583	DNA-binding transcription factor activity
G8E09_11470	COG1045	serine acetyltransferase
G8E09_11475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G8E09_11480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G8E09_11485	COG1280	lysine exporter protein (LysE YggA)
G8E09_11495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E09_11500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G8E09_11510	COG0765	amino acid transport
G8E09_11515	COG0765	amino acid transport
G8E09_11535	COG0784	Response regulator, receiver
G8E09_11535	COG2205	protein histidine kinase activity
G8E09_11555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G8E09_11575	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_11625	COG0583	DNA-binding transcription factor activity
G8E09_11635	COG2814	Major facilitator Superfamily
G8E09_11650	COG0318	PFAM AMP-dependent synthetase and ligase
G8E09_11655	COG1309	transcriptional regulator
G8E09_11660	COG1960	acyl-CoA dehydrogenase activity
G8E09_11665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G8E09_11670	COG1024	Enoyl-CoA hydratase
G8E09_11675	COG4770	biotin carboxylase activity
G8E09_11685	COG0583	DNA-binding transcription factor activity
G8E09_11700	COG1960	acyl-CoA dehydrogenase activity
G8E09_11710	COG2814	Major facilitator Superfamily
G8E09_11720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G8E09_11725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G8E09_11730	COG2814	Major facilitator Superfamily
G8E09_11735	COG1960	acyl-CoA dehydrogenase activity
G8E09_11740	COG1024	Enoyl-CoA hydratase
G8E09_11745	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_11750	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E09_11755	COG0183	Belongs to the thiolase family
G8E09_11765	COG2814	Major facilitator Superfamily
G8E09_11775	COG1024	Enoyl-CoA hydratase
G8E09_11785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G8E09_11790	COG1960	acyl-CoA dehydrogenase activity
G8E09_11795	COG2814	Major facilitator Superfamily
G8E09_11800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G8E09_11805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G8E09_11820	COG3842	ATPase activity
G8E09_11825	COG1840	ABC-type Fe3 transport system, periplasmic component
G8E09_11840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_11845	COG1414	Transcriptional regulator
G8E09_11855	COG0583	DNA-binding transcription factor activity
G8E09_11885	COG2050	protein possibly involved in aromatic compounds catabolism
G8E09_11895	COG3327	negative regulation of DNA-templated transcription, initiation
G8E09_11900	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G8E09_11905	COG0183	Belongs to the thiolase family
G8E09_11910	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E09_11915	COG1024	Enoyl-CoA hydratase
G8E09_11920	COG1024	Enoyl-CoA hydratase
G8E09_11925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E09_11930	COG2151	metal-sulfur cluster biosynthetic enzyme
G8E09_11935	COG3396	Phenylacetate-CoA oxygenase
G8E09_11940	COG3460	Phenylacetate-CoA oxygenase
G8E09_11945	COG3396	Phenylacetate-CoA oxygenase
G8E09_11950	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_11950	COG2030	dehydratase
G8E09_11955	COG1760	l-serine dehydratase
G8E09_11970	COG0789	Transcriptional regulator
G8E09_11980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G8E09_11985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E09_12040	COG2885	chlorophyll binding
G8E09_12095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8E09_12125	COG3209	COG3209 Rhs family protein
G8E09_12155	COG1116	anion transmembrane transporter activity
G8E09_12170	COG0864	Transcriptional regulator
G8E09_12185	COG1733	regulation of RNA biosynthetic process
G8E09_12190	COG2249	NAD(P)H dehydrogenase (quinone) activity
G8E09_12195	COG0439	Biotin carboxylase
G8E09_12210	COG1063	alcohol dehydrogenase
G8E09_12215	COG1250	3-hydroxyacyl-CoA dehydrogenase
G8E09_12245	COG0038	chloride channel
G8E09_12250	COG4770	biotin carboxylase activity
G8E09_12270	COG1914	H( )-stimulated, divalent metal cation uptake system
G8E09_12285	COG1595	DNA-templated transcription, initiation
G8E09_12295	COG3220	belongs to the UPF0276 family
G8E09_12345	COG0702	epimerase
G8E09_12350	COG1733	regulation of RNA biosynthetic process
G8E09_12365	COG1309	transcriptional regulator
G8E09_12430	COG3038	cytochrome b561
G8E09_12435	COG0753	catalase activity
G8E09_12460	COG1278	Cold shock
G8E09_12495	COG1522	sequence-specific DNA binding
G8E09_12500	COG0531	amino acid
G8E09_12505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G8E09_12520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G8E09_12535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G8E09_12545	COG4122	O-methyltransferase activity
G8E09_12575	COG1538	Outer membrane efflux protein
G8E09_12580	COG1137	ATPase activity
G8E09_12585	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G8E09_12595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G8E09_12645	COG2814	Major facilitator Superfamily
G8E09_12655	COG0668	transmembrane transport
G8E09_12715	COG2226	methyltransferase
G8E09_12720	COG1011	Hydrolase
G8E09_12745	COG1278	Cold shock
G8E09_12750	COG1560	Kdo2-lipid A biosynthetic process
G8E09_12755	COG1280	lysine exporter protein (LysE YggA)
G8E09_12790	COG1570	exodeoxyribonuclease VII activity
G8E09_12875	COG2871	sodium ion transport
G8E09_12885	COG0583	DNA-binding transcription factor activity
G8E09_12895	COG4638	Rieske (2fe-2S)
G8E09_12900	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G8E09_12905	COG0633	Ferredoxin
G8E09_12905	COG0543	2 iron, 2 sulfur cluster binding
G8E09_12910	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_12915	COG3135	benzoate transporter
G8E09_12920	COG2814	Major facilitator Superfamily
G8E09_12935	COG1643	Atp-dependent helicase
G8E09_12960	COG3634	alkyl hydroperoxide reductase activity
G8E09_12980	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G8E09_12995	COG0625	glutathione transferase activity
G8E09_13005	COG2885	chlorophyll binding
G8E09_13040	COG0542	response to heat
G8E09_13055	COG1765	OsmC-like protein
G8E09_13070	COG0667	Aldo Keto reductase
G8E09_13085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G8E09_13095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G8E09_13105	COG0527	aspartate kinase activity
G8E09_13115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G8E09_13125	COG3038	cytochrome b561
G8E09_13130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G8E09_13135	COG2252	PERMEase
G8E09_13145	COG1741	Belongs to the pirin family
G8E09_13150	COG1309	transcriptional regulator
G8E09_13165	COG2072	flavoprotein involved in K transport
G8E09_13170	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
G8E09_13175	COG0583	DNA-binding transcription factor activity
G8E09_13190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G8E09_13220	COG1944	ATP diphosphatase activity
G8E09_13240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8E09_13255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G8E09_13275	COG2814	Major facilitator Superfamily
G8E09_13280	COG1024	Enoyl-CoA hydratase
G8E09_13285	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_13295	COG1960	acyl-CoA dehydrogenase activity
G8E09_13320	COG0697	spore germination
G8E09_13345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G8E09_13360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G8E09_13375	COG1157	protein secretion by the type III secretion system
G8E09_13390	COG1766	The M ring may be actively involved in energy transduction
G8E09_13395	COG1677	Flagellar hook-basal body complex protein FliE
G8E09_13400	COG1558	bacterial-type flagellum-dependent cell motility
G8E09_13410	COG1706	bacterial-type flagellum-dependent cell motility
G8E09_13415	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G8E09_13425	COG4786	Flagellar basal body rod
G8E09_13435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G8E09_13440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G8E09_13445	COG1684	flagellar biosynthetic protein fliR
G8E09_13450	COG1987	bacterial-type flagellum assembly
G8E09_13480	COG1113	amino acid transport
G8E09_13500	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_13520	COG0531	amino acid
G8E09_13530	COG1113	amino acid transport
G8E09_13555	COG3501	Rhs element vgr protein
G8E09_13565	COG4269	membrane
G8E09_13585	COG1902	pentaerythritol trinitrate reductase activity
G8E09_13585	COG0446	pyridine nucleotide-disulphide oxidoreductase
G8E09_13595	COG5001	Diguanylate cyclase
G8E09_13595	COG4251	negative regulation of phosphorylation
G8E09_13595	COG3706	GGDEF domain
G8E09_13595	COG2203	Gaf domain
G8E09_13605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G8E09_13630	COG4172	Belongs to the ABC transporter superfamily
G8E09_13635	COG4239	(ABC) transporter, permease
G8E09_13640	COG4174	ABC transporter (Permease)
G8E09_13645	COG4166	transmembrane transport
G8E09_13650	COG1388	LysM domain
G8E09_13650	COG0741	lytic transglycosylase activity
G8E09_13695	COG0583	DNA-binding transcription factor activity
G8E09_13700	COG1279	arginine transmembrane transporter activity
G8E09_13710	COG0789	Transcriptional regulator
G8E09_13720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_13725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_13730	COG0006	proline dipeptidase activity
G8E09_13770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G8E09_13785	COG3384	dioxygenase
G8E09_13795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G8E09_13800	COG2878	Part of a membrane complex involved in electron transport
G8E09_13805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G8E09_13830	COG0768	penicillin binding
G8E09_13835	COG0742	ribosomal rna small subunit methyltransferase
G8E09_13850	COG0830	nickel cation binding
G8E09_13860	COG0804	urea catabolic process
G8E09_13885	COG3015	lipoprotein NlpE involved in copper resistance
G8E09_13900	COG1253	flavin adenine dinucleotide binding
G8E09_13905	COG2851	Citrate transporter
G8E09_13955	COG1773	rubredoxin
G8E09_13960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G8E09_13965	COG2267	carboxylic ester hydrolase activity
G8E09_13970	COG0583	DNA-binding transcription factor activity
G8E09_14000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G8E09_14005	COG4181	ATPase activity
G8E09_14030	COG4771	TonB-dependent receptor
G8E09_14050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8E09_14070	COG0306	phosphate transporter
G8E09_14080	COG3958	Transketolase
G8E09_14085	COG3959	Transketolase, thiamine diphosphate binding domain
G8E09_14095	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_14100	COG0583	DNA-binding transcription factor activity
G8E09_14115	COG2223	nitrite transmembrane transporter activity
G8E09_14120	COG2207	Transcriptional regulator
G8E09_14125	COG2066	Belongs to the glutaminase family
G8E09_14130	COG0242	peptide deformylase activity
G8E09_14135	COG0477	Major facilitator Superfamily
G8E09_14145	COG0028	Belongs to the TPP enzyme family
G8E09_14160	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_14165	COG2267	carboxylic ester hydrolase activity
G8E09_14175	COG2271	Major facilitator Superfamily
G8E09_14190	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_14210	COG1414	Transcriptional regulator
G8E09_14225	COG1024	Enoyl-CoA hydratase
G8E09_14235	COG1215	transferase activity, transferring glycosyl groups
G8E09_14240	COG0726	polysaccharide deacetylase
G8E09_14240	COG1649	PFAM Uncharacterised BCR, COG1649
G8E09_14250	COG4681	YaeQ
G8E09_14260	COG0523	cobalamin synthesis protein
G8E09_14270	COG1607	acyl-coa hydrolase
G8E09_14280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G8E09_14285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G8E09_14290	COG1309	transcriptional regulator
G8E09_14315	COG2040	homocysteine
G8E09_14320	COG0531	amino acid
G8E09_14375	COG1595	DNA-templated transcription, initiation
G8E09_14435	COG0405	Gamma-glutamyltransferase
G8E09_14440	COG2814	Major facilitator Superfamily
G8E09_14450	COG2050	protein possibly involved in aromatic compounds catabolism
G8E09_14465	COG1090	epimerase
G8E09_14485	COG0420	3'-5' exonuclease activity
G8E09_14510	COG0735	belongs to the Fur family
G8E09_14515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E09_14520	COG2914	Belongs to the UPF0125 (RnfH) family
G8E09_14535	COG0121	glutamine amidotransferase
G8E09_14550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G8E09_14560	COG0210	DNA helicase
G8E09_14565	COG2885	chlorophyll binding
G8E09_14570	COG0204	Acyl-transferase
G8E09_14585	COG2894	cell division
G8E09_14605	COG1280	lysine exporter protein (LysE YggA)
G8E09_14610	COG1674	ftsk spoiiie
G8E09_14615	COG0492	ferredoxin-NADP+ reductase activity
G8E09_14620	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G8E09_14630	COG0456	acetyltransferase
G8E09_14645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G8E09_14650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G8E09_14660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G8E09_14685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G8E09_14685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G8E09_14705	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_14710	COG4638	Rieske (2fe-2S)
G8E09_14725	COG0473	3-isopropylmalate dehydrogenase activity
G8E09_14730	COG0583	DNA-binding transcription factor activity
G8E09_14750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G8E09_14785	COG0358	DNA primase activity
G8E09_14800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G8E09_14830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G8E09_14860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G8E09_14870	COG0351	phosphomethylpyrimidine kinase
G8E09_14870	COG0352	thiamine-phosphate diphosphorylase activity
G8E09_14870	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G8E09_14875	COG1652	LysM domain
G8E09_14885	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_14900	COG1399	metal-binding, possibly nucleic acid-binding protein
G8E09_14905	COG3101	peptidyl-lysine hydroxylation
G8E09_14910	COG0009	L-threonylcarbamoyladenylate synthase
G8E09_14915	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G8E09_14920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G8E09_14935	COG4106	trans-aconitate 2-methyltransferase activity
G8E09_14950	COG2226	methyltransferase
G8E09_14950	COG0596	Alpha beta hydrolase
G8E09_14950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G8E09_14960	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G8E09_14965	COG2223	nitrite transmembrane transporter activity
G8E09_14985	COG1196	nuclear chromosome segregation
G8E09_14995	COG0730	response to heat
G8E09_15010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G8E09_15020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G8E09_15065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G8E09_15070	COG0489	protein tyrosine kinase activity
G8E09_15080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8E09_15080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8E09_15115	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G8E09_15120	COG2081	HI0933 family
G8E09_15130	COG0668	transmembrane transport
G8E09_15150	COG0583	DNA-binding transcription factor activity
G8E09_15170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8E09_15175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G8E09_15205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G8E09_15230	COG2199	diguanylate cyclase activity
G8E09_15240	COG2205	protein histidine kinase activity
G8E09_15245	COG0745	RESPONSE REGULATOR receiver
G8E09_15260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G8E09_15265	COG0384	phenazine biosynthesis protein PhzF
G8E09_15315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G8E09_15330	COG0583	DNA-binding transcription factor activity
G8E09_15350	COG1473	amidohydrolase
G8E09_15380	COG0583	DNA-binding transcription factor activity
G8E09_15395	COG0583	DNA-binding transcription factor activity
G8E09_15400	COG1053	succinate dehydrogenase
G8E09_15415	COG1309	transcriptional regulator
G8E09_15425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G8E09_15430	COG2814	Major facilitator Superfamily
G8E09_15435	COG1960	acyl-CoA dehydrogenase activity
G8E09_15440	COG0583	DNA-binding transcription factor activity
G8E09_15445	COG1063	alcohol dehydrogenase
G8E09_15475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G8E09_15480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G8E09_15505	COG2132	Multicopper oxidase
G8E09_15515	COG0561	phosphatase activity
G8E09_15520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G8E09_15530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G8E09_15545	COG1214	PFAM Peptidase M22, glycoprotease
G8E09_15605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G8E09_15610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G8E09_15615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G8E09_15675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G8E09_15685	COG1846	Transcriptional regulator
G8E09_15690	COG1764	response to oxidative stress
G8E09_15730	COG0037	tRNA processing
G8E09_15740	COG0248	Ppx GppA phosphatase
G8E09_15770	COG0072	phenylalanine-tRNA ligase activity
G8E09_15800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G8E09_15815	COG1238	metal cluster binding
G8E09_15820	COG0625	glutathione transferase activity
G8E09_15835	COG0318	PFAM AMP-dependent synthetase and ligase
G8E09_15840	COG3028	Belongs to the UPF0307 family
G8E09_15845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G8E09_15865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G8E09_15870	COG0617	tRNA 3'-terminal CCA addition
G8E09_15875	COG1555	photosystem II stabilization
G8E09_15880	COG3956	TIGRFAM MazG family protein
G8E09_15890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G8E09_15905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G8E09_15910	COG5002	protein histidine kinase activity
G8E09_15910	COG0784	Response regulator, receiver
G8E09_15910	COG2205	protein histidine kinase activity
G8E09_15915	COG1024	Enoyl-CoA hydratase
G8E09_15920	COG2084	Dehydrogenase
G8E09_15925	COG3622	Belongs to the hyi family
G8E09_15955	COG0697	spore germination
G8E09_15965	COG2814	Major facilitator Superfamily
G8E09_15990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G8E09_16015	COG3501	Rhs element vgr protein
G8E09_16095	COG4772	TonB-dependent receptor
G8E09_16105	COG3340	Belongs to the peptidase S51 family
G8E09_16135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G8E09_16145	COG0583	DNA-binding transcription factor activity
G8E09_16155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G8E09_16165	COG0084	hydrolase, TatD family'
G8E09_16180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G8E09_16200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G8E09_16205	COG0440	acetolactate synthase activity
G8E09_16210	COG0028	Belongs to the TPP enzyme family
G8E09_16230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8E09_16235	COG1136	(ABC) transporter
G8E09_16235	COG0577	efflux transmembrane transporter activity
G8E09_16255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G8E09_16260	COG1162	GTPase activity
G8E09_16270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G8E09_16290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G8E09_16295	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_16335	COG2986	histidine ammonia-lyase
G8E09_16345	COG1216	Glycosyl transferase, family 2
G8E09_16360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G8E09_16385	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E09_16405	COG1426	Protein conserved in bacteria
G8E09_16440	COG0793	Belongs to the peptidase S41A family
G8E09_16455	COG2267	carboxylic ester hydrolase activity
G8E09_16465	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_16470	COG3265	gluconokinase activity
G8E09_16480	COG0800	Aldolase
G8E09_16495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G8E09_16500	COG0857	belongs to the CobB CobQ family
G8E09_16500	COG0280	phosphate acetyltransferase
G8E09_16505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G8E09_16505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G8E09_16525	COG0740	serine-type endopeptidase activity
G8E09_16535	COG4774	siderophore transport
G8E09_16545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G8E09_16555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G8E09_16555	COG2813	Specifically methylates the guanine in position
G8E09_16650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G8E09_16675	COG0251	oxidation-reduction process
G8E09_16690	COG0583	DNA-binding transcription factor activity
G8E09_16710	COG0235	Class ii aldolase
G8E09_16715	COG0477	Major facilitator Superfamily
G8E09_16725	COG1012	belongs to the aldehyde dehydrogenase family
G8E09_16735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G8E09_16740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G8E09_16745	COG1113	amino acid transport
G8E09_16755	COG1522	sequence-specific DNA binding
G8E09_16760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G8E09_16770	COG2207	Transcriptional regulator
G8E09_16790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G8E09_16835	COG0788	formyltetrahydrofolate deformylase activity
G8E09_16860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G8E09_16860	COG4651	solute:proton antiporter activity
G8E09_16880	COG0724	RNA recognition motif
G8E09_16885	COG0210	DNA helicase
G8E09_16910	COG1733	regulation of RNA biosynthetic process
G8E09_16920	COG2900	Belongs to the SlyX family
G8E09_16935	COG1560	Kdo2-lipid A biosynthetic process
G8E09_16945	COG1301	dicarboxylic acid transport
G8E09_17000	COG0473	3-isopropylmalate dehydrogenase activity
G8E09_17025	COG0583	DNA-binding transcription factor activity
G8E09_17065	COG0583	DNA-binding transcription factor activity
G8E09_17075	COG0625	glutathione transferase activity
G8E09_17080	COG2378	regulation of single-species biofilm formation
G8E09_17085	COG0546	phosphoglycolate phosphatase activity
G8E09_17100	COG1530	ribonuclease E activity
G8E09_17105	COG0318	PFAM AMP-dependent synthetase and ligase
G8E09_17120	COG0583	DNA-binding transcription factor activity
G8E09_17125	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_17130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G8E09_17140	COG0534	Mate efflux family protein
G8E09_17155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G8E09_17180	COG0493	'glutamate synthase
G8E09_17190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G8E09_17195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G8E09_17210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G8E09_17220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G8E09_17220	COG0644	oxidoreductase
G8E09_17235	COG4535	Mg2 and Co2 transporter CorC
G8E09_17245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8E09_17265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G8E09_17275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G8E09_17285	COG0484	heat shock protein binding
G8E09_17290	COG0789	Transcriptional regulator
G8E09_17295	COG0598	Magnesium transport protein CorA
G8E09_17300	COG1185	polyribonucleotide nucleotidyltransferase activity
G8E09_17315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G8E09_17320	COG1074	ATP-dependent DNA helicase activity
G8E09_17325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G8E09_17345	COG2226	methyltransferase
G8E09_17355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G8E09_17370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G8E09_17385	COG2111	Na H antiporter
G8E09_17385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G8E09_17390	COG1006	Multisubunit Na H antiporter MnhC subunit
G8E09_17395	COG0651	ATP synthesis coupled electron transport
G8E09_17405	COG2212	antiporter activity
G8E09_17415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G8E09_17425	COG0195	Participates in both transcription termination and antitermination
G8E09_17475	COG0237	dephospho-CoA kinase activity
G8E09_17485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8E09_17500	COG0497	DNA recombination
G8E09_17510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G8E09_17545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G8E09_17545	COG2169	Transcriptional regulator
G8E09_17550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G8E09_17595	COG0326	Molecular chaperone. Has ATPase activity
G8E09_17615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G8E09_17630	COG0326	Molecular chaperone. Has ATPase activity
G8E09_17645	COG2056	Na+-H+ antiporter family
G8E09_17715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G8E09_17745	COG0546	phosphoglycolate phosphatase activity
G8E09_17750	COG1716	ATPase activity
G8E09_17795	COG0181	hydroxymethylbilane synthase activity
G8E09_17805	COG3275	phosphorelay sensor kinase activity
G8E09_17825	COG1538	Outer membrane efflux protein
G8E09_17835	COG0697	spore germination
G8E09_17855	COG0494	nUDIX hydrolase
G8E09_17860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G8E09_17865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G8E09_17870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G8E09_17875	COG0772	Belongs to the SEDS family
G8E09_17900	COG4974	Belongs to the 'phage' integrase family
G8E09_17905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G8E09_17915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G8E09_17925	COG2197	response regulator
G8E09_17940	COG0793	Belongs to the peptidase S41A family
G8E09_17945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G8E09_17950	COG0795	lipopolysaccharide-transporting ATPase activity
G8E09_17990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G8E09_17990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G8E09_18000	COG0004	ammonium transporteR
G8E09_18005	COG0347	Belongs to the P(II) protein family
G8E09_18015	COG0606	chelatase, subunit chli
G8E09_18020	COG0431	NADPH-dependent FMN reductase
G8E09_18025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8E09_18030	COG0235	Class ii aldolase
G8E09_18035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G8E09_18055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G8E09_18070	COG0318	PFAM AMP-dependent synthetase and ligase
G8E09_18080	COG0477	Major facilitator Superfamily
G8E09_18085	COG2860	membrane
G8E09_18095	COG1253	flavin adenine dinucleotide binding
G8E09_18105	COG2814	Major facilitator Superfamily
G8E09_18115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G8E09_18125	COG0745	RESPONSE REGULATOR receiver
G8E09_18130	COG2205	protein histidine kinase activity
G8E09_18135	COG4452	Inner membrane protein CreD
G8E09_18175	COG0655	NAD(P)H dehydrogenase (quinone) activity
G8E09_18190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G8E09_18220	COG1309	transcriptional regulator
G8E09_18255	COG0758	DNA mediated transformation
G8E09_18265	COG0697	spore germination
G8E09_18270	COG1309	transcriptional regulator
G8E09_18285	COG0386	Belongs to the glutathione peroxidase family
G8E09_18300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G8E09_18310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G8E09_18350	COG1121	(ABC) transporter
G8E09_18355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G8E09_18360	COG1280	lysine exporter protein (LysE YggA)
G8E09_18365	COG2837	iron assimilation
G8E09_18370	COG0281	malic enzyme
G8E09_18415	COG0519	Catalyzes the synthesis of GMP from XMP
G8E09_18415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G8E09_18420	COG4399	Belongs to the UPF0754 family
G8E09_18425	COG2259	Doxx family
G8E09_18430	COG0586	Pfam SNARE associated Golgi protein
G8E09_18445	COG1192	Involved in chromosome partitioning
G8E09_18455	COG0271	Belongs to the BolA IbaG family
G8E09_18495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G8E09_18495	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G8E09_18495	COG3321	synthase
G8E09_18495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G8E09_18500	COG1960	acyl-CoA dehydrogenase activity
G8E09_18505	COG0318	PFAM AMP-dependent synthetase and ligase
G8E09_18510	COG2197	response regulator
G8E09_18520	COG3916	Acyl-homoserine-lactone synthase
G8E09_18525	COG0477	Major facilitator Superfamily
G8E09_18530	COG1024	Enoyl-CoA hydratase
G8E09_18535	COG1024	Enoyl-CoA hydratase
G8E09_18540	COG1960	acyl-CoA dehydrogenase activity
G8E09_18545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G8E09_18565	COG1113	amino acid transport
G8E09_18570	COG1113	amino acid transport
G8E09_18575	COG0251	oxidation-reduction process
G8E09_18615	COG0564	pseudouridine synthase activity
G8E09_18660	COG1051	belongs to the nudix hydrolase family
G8E09_18680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G8E09_18695	COG1802	Transcriptional regulator
G8E09_18705	COG1448	Aminotransferase
G8E09_18710	COG0277	FAD linked oxidase domain protein
G8E09_18720	COG2186	Transcriptional regulator
G8E09_18730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G8E09_18735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G8E09_18750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G8E09_18760	COG0110	maltose O-acetyltransferase activity
G8E09_18765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G8E09_18780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G8E09_18815	COG1083	cytidylyl-transferase
G8E09_18820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G8E09_18830	COG2089	acid synthase
G8E09_18835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G8E09_18840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G8E09_18850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G8E09_18855	COG1596	polysaccharide export
G8E09_18880	COG0728	peptidoglycan biosynthetic process
G8E09_18885	COG3023	N-Acetylmuramoyl-L-alanine amidase
G8E09_18940	COG0546	phosphoglycolate phosphatase activity
G8E09_18945	COG1028	Short-chain dehydrogenase reductase Sdr
G8E09_18960	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G8E09_18960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G8E09_18965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E09_18970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G8E09_18975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G8E09_18980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G8E09_18985	COG1116	anion transmembrane transporter activity
G8E09_18990	COG1309	transcriptional regulator
G8E09_18995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G8E09_19005	COG0196	riboflavin kinase activity
G8E09_19010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G8E09_19020	COG1047	Peptidyl-prolyl cis-trans
G8E09_19060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G8E09_19115	COG2951	lytic endotransglycosylase activity
G8E09_19120	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G8E09_19135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G8E09_19145	COG0671	phosphoesterase, PA-phosphatase related
G8E09_19150	COG0861	Integral membrane protein TerC family
G8E09_19160	COG0754	glutathionylspermidine amidase activity
G8E09_19170	COG0402	S-adenosylhomocysteine deaminase activity
G8E09_19185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G8E09_19190	COG1230	cation diffusion facilitator family transporter
G8E09_19205	COG0706	membrane insertase activity
G8E09_19270	COG2026	Addiction module toxin, RelE StbE family
G8E09_19315	COG1192	Involved in chromosome partitioning
G8E09_19560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G8E09_19660	COG3504	Conjugal transfer protein
G8E09_19665	COG2948	multi-organism process
G8E09_19715	COG4683	PFAM Phage derived protein Gp49-like (DUF891)