locus-tag	class	description
AYJ52_00015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYJ52_00040	COG3293	Transposase
AYJ52_00060	COG0628	permease
AYJ52_00070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYJ52_00075	COG0596	Alpha beta hydrolase
AYJ52_00080	COG0616	signal peptide processing
AYJ52_00080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYJ52_00090	COG2333	competence protein COMEC
AYJ52_00090	COG0658	competence protein
AYJ52_00095	COG1136	(ABC) transporter
AYJ52_00100	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYJ52_00120	COG2801	Transposase and inactivated derivatives
AYJ52_00140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_00170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYJ52_00175	COG1280	lysine exporter protein (LysE YggA)
AYJ52_00190	COG0019	diaminopimelate decarboxylase activity
AYJ52_00200	COG1113	amino acid transport
AYJ52_00205	COG1115	amino acid carrier protein
AYJ52_00235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AYJ52_00245	COG1929	Belongs to the glycerate kinase type-1 family
AYJ52_00260	COG0778	Nitroreductase
AYJ52_00285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYJ52_00310	COG0741	lytic transglycosylase activity
AYJ52_00330	COG0584	glycerophosphoryl diester phosphodiesterase
AYJ52_00345	COG0582	viral genome integration into host DNA
AYJ52_00360	COG2801	Transposase and inactivated derivatives
AYJ52_00390	COG3293	Transposase
AYJ52_00395	COG2814	Major facilitator Superfamily
AYJ52_00435	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_00445	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AYJ52_00450	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_00525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYJ52_00545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYJ52_00550	COG0477	Major facilitator Superfamily
AYJ52_00600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYJ52_00605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYJ52_00630	COG0505	Belongs to the CarA family
AYJ52_00645	COG1309	transcriptional regulator
AYJ52_00650	COG0251	oxidation-reduction process
AYJ52_00660	COG0589	response to stress
AYJ52_00680	COG2843	Capsule synthesis protein
AYJ52_00695	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_00710	COG2321	neutral zinc metallopeptidase
AYJ52_00715	COG2354	Protein conserved in bacteria
AYJ52_00735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ52_00755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYJ52_00760	COG1053	succinate dehydrogenase
AYJ52_00765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AYJ52_00770	COG2009	succinate dehydrogenase
AYJ52_00810	COG2921	Belongs to the UPF0250 family
AYJ52_00815	COG0321	lipoyl(octanoyl) transferase activity
AYJ52_00830	COG0531	amino acid
AYJ52_00865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYJ52_00870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYJ52_00870	COG1648	precorrin-2 dehydrogenase activity
AYJ52_00885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AYJ52_00910	COG0671	phosphoesterase, PA-phosphatase related
AYJ52_00915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_00925	COG1538	Outer membrane efflux protein
AYJ52_00930	COG0393	Putative heavy-metal-binding
AYJ52_00935	COG0393	Putative heavy-metal-binding
AYJ52_00945	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_00955	COG0525	valine-tRNA ligase activity
AYJ52_00970	COG2801	Transposase and inactivated derivatives
AYJ52_00990	COG0583	DNA-binding transcription factor activity
AYJ52_00995	COG0004	ammonium transporteR
AYJ52_01005	COG0642	Histidine kinase
AYJ52_01010	COG0745	RESPONSE REGULATOR receiver
AYJ52_01015	COG2194	sulfuric ester hydrolase activity
AYJ52_01040	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYJ52_01055	COG2315	Protein conserved in bacteria
AYJ52_01060	COG0142	geranyltranstransferase activity
AYJ52_01065	COG2828	Protein conserved in bacteria
AYJ52_01070	COG1113	amino acid transport
AYJ52_01080	COG3046	protein related to deoxyribodipyrimidine photolyase
AYJ52_01095	COG0582	viral genome integration into host DNA
AYJ52_01130	COG0305	Participates in initiation and elongation during chromosome replication
AYJ52_01180	COG0464	growth
AYJ52_01200	COG2207	Transcriptional regulator
AYJ52_01225	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYJ52_01245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYJ52_01250	COG1530	ribonuclease E activity
AYJ52_01255	COG0424	maF-like protein
AYJ52_01260	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AYJ52_01265	COG1792	Involved in formation and maintenance of cell shape
AYJ52_01270	COG1077	Cell shape determining protein MreB Mrl
AYJ52_01275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ52_01285	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ52_01290	COG2801	Transposase and inactivated derivatives
AYJ52_01320	COG3293	Transposase
AYJ52_01330	COG3590	peptidase
AYJ52_01335	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AYJ52_01340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYJ52_01345	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYJ52_01350	COG1115	amino acid carrier protein
AYJ52_01365	COG2814	Major facilitator Superfamily
AYJ52_01370	COG1289	transmembrane transporter activity
AYJ52_01380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AYJ52_01420	COG1376	ErfK ybiS ycfS ynhG family protein
AYJ52_01425	COG2832	Protein of unknown function (DUF454)
AYJ52_01435	COG5510	response to toxic substance
AYJ52_01465	COG3293	Transposase
AYJ52_01475	COG0840	transmembrane signaling receptor activity
AYJ52_01515	COG3422	double-strand break repair
AYJ52_01520	COG2824	Alkylphosphonate utilization operon protein PhnA
AYJ52_01525	COG3189	MarR family transcriptional regulator
AYJ52_01530	COG0596	Alpha beta hydrolase
AYJ52_01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ52_01545	COG1335	isochorismatase
AYJ52_01550	COG0251	oxidation-reduction process
AYJ52_01555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ52_01560	COG2233	PERMEase
AYJ52_01575	COG0354	folic acid binding
AYJ52_01580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYJ52_01590	COG0679	Auxin Efflux Carrier
AYJ52_01595	COG1902	pentaerythritol trinitrate reductase activity
AYJ52_01600	COG4772	TonB-dependent receptor
AYJ52_01605	COG2094	Belongs to the DNA glycosylase MPG family
AYJ52_01640	COG2233	PERMEase
AYJ52_01650	COG0833	amino acid
AYJ52_01655	COG1690	Belongs to the RtcB family
AYJ52_01660	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYJ52_01660	COG2885	chlorophyll binding
AYJ52_01670	COG0183	Belongs to the thiolase family
AYJ52_01690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ52_01710	COG2207	Transcriptional regulator
AYJ52_01715	COG0183	Belongs to the thiolase family
AYJ52_01735	COG2153	protein acetylation
AYJ52_01745	COG1272	protein, Hemolysin III
AYJ52_01750	COG0477	Major facilitator Superfamily
AYJ52_01765	COG0450	alkyl hydroperoxide reductase
AYJ52_01785	COG0285	dihydrofolate synthase activity
AYJ52_01820	COG0133	tryptophan synthase activity
AYJ52_01830	COG4206	TonB-dependent receptor
AYJ52_01835	COG2096	Adenosyltransferase
AYJ52_01840	COG0584	glycerophosphoryl diester phosphodiesterase
AYJ52_01855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AYJ52_01865	COG0745	RESPONSE REGULATOR receiver
AYJ52_01870	COG2205	protein histidine kinase activity
AYJ52_01880	COG1960	acyl-CoA dehydrogenase activity
AYJ52_01885	COG1960	acyl-CoA dehydrogenase activity
AYJ52_01935	COG1442	glycosyl transferase family 8
AYJ52_01950	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_01960	COG0438	transferase activity, transferring glycosyl groups
AYJ52_01970	COG0438	transferase activity, transferring glycosyl groups
AYJ52_01975	COG0726	polysaccharide deacetylase
AYJ52_01990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AYJ52_02030	COG1862	Preprotein translocase
AYJ52_02040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ52_02045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYJ52_02055	COG3781	membrane
AYJ52_02070	COG2350	Protein conserved in bacteria
AYJ52_02105	COG1607	acyl-coa hydrolase
AYJ52_02120	COG3453	Protein conserved in bacteria
AYJ52_02120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ52_02170	COG2199	diguanylate cyclase activity
AYJ52_02175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYJ52_02175	COG2885	chlorophyll binding
AYJ52_02180	COG1408	metallophosphoesterase
AYJ52_02190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ52_02200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYJ52_02220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYJ52_02225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYJ52_02230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AYJ52_02235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AYJ52_02240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AYJ52_02250	COG2969	positive regulation of protein catabolic process
AYJ52_02285	COG2801	Transposase and inactivated derivatives
AYJ52_02305	COG1960	acyl-CoA dehydrogenase activity
AYJ52_02310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYJ52_02325	COG1309	transcriptional regulator
AYJ52_02330	COG1960	acyl-CoA dehydrogenase activity
AYJ52_02375	COG1183	phosphatidylcholine synthase activity
AYJ52_02380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYJ52_02410	COG1196	nuclear chromosome segregation
AYJ52_02410	COG0741	lytic transglycosylase activity
AYJ52_02410	COG0739	heme binding
AYJ52_02420	COG1702	phosphate starvation-inducible protein PhoH
AYJ52_02455	COG1295	ribonuclease BN
AYJ52_02505	COG0557	exoribonuclease II activity
AYJ52_02510	COG0339	signal peptide processing
AYJ52_02515	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AYJ52_02545	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AYJ52_02550	COG1960	acyl-CoA dehydrogenase activity
AYJ52_02575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYJ52_02585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AYJ52_02685	COG0088	Forms part of the polypeptide exit tunnel
AYJ52_02690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AYJ52_02705	COG0626	cystathionine gamma-synthase activity
AYJ52_02710	COG0433	COG0433 Predicted ATPase
AYJ52_02715	COG1017	nitric oxide dioxygenase activity
AYJ52_02715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYJ52_02720	COG1959	2 iron, 2 sulfur cluster binding
AYJ52_02735	COG1301	dicarboxylic acid transport
AYJ52_02740	COG1946	Acyl-CoA thioesterase
AYJ52_02760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYJ52_02765	COG1040	competence protein
AYJ52_02780	COG0598	Magnesium transport protein CorA
AYJ52_02790	COG2854	intermembrane phospholipid transfer
AYJ52_02800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYJ52_02805	COG1127	ABC transporter
AYJ52_02815	COG0513	Belongs to the DEAD box helicase family
AYJ52_02835	COG0408	coproporphyrinogen oxidase activity
AYJ52_02850	COG1960	acyl-CoA dehydrogenase activity
AYJ52_02860	COG1983	PspC domain protein
AYJ52_02865	COG4109	DRTGG domain
AYJ52_02895	COG0752	glycyl-tRNA synthetase alpha subunit
AYJ52_02915	COG0583	DNA-binding transcription factor activity
AYJ52_02955	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_02965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYJ52_02970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ52_02975	COG0833	amino acid
AYJ52_03005	COG1192	Involved in chromosome partitioning
AYJ52_03010	COG0628	permease
AYJ52_03020	COG1289	transmembrane transporter activity
AYJ52_03035	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYJ52_03040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AYJ52_03050	COG0277	FAD linked oxidase domain protein
AYJ52_03055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ52_03060	COG5006	permease, DMT superfamily
AYJ52_03065	COG5006	permease, DMT superfamily
AYJ52_03080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYJ52_03085	COG5380	lipid catabolic process
AYJ52_03095	COG0335	large ribosomal subunit rRNA binding
AYJ52_03105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYJ52_03155	COG0194	GDP metabolic process
AYJ52_03165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYJ52_03185	COG3307	-O-antigen
AYJ52_03205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYJ52_03210	COG1704	LemA family
AYJ52_03220	COG0493	'glutamate synthase
AYJ52_03225	COG0070	glutamate synthase
AYJ52_03225	COG0069	glutamate synthase activity
AYJ52_03225	COG0067	glutamate synthase
AYJ52_03275	COG2226	methyltransferase
AYJ52_03290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYJ52_03295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYJ52_03340	COG0833	amino acid
AYJ52_03420	COG0488	(ABC) transporter
AYJ52_03435	COG2814	Major facilitator Superfamily
AYJ52_03445	COG4221	oxidoreductase activity
AYJ52_03450	COG0659	secondary active sulfate transmembrane transporter activity
AYJ52_03460	COG0745	RESPONSE REGULATOR receiver
AYJ52_03465	COG2205	protein histidine kinase activity
AYJ52_03470	COG0427	acetyl-CoA hydrolase
AYJ52_03475	COG0456	acetyltransferase
AYJ52_03480	COG2801	Transposase and inactivated derivatives
AYJ52_03510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYJ52_03530	COG1132	(ABC) transporter
AYJ52_03555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYJ52_03610	COG0582	viral genome integration into host DNA
AYJ52_03675	COG2801	Transposase and inactivated derivatives
AYJ52_03685	COG2801	Transposase and inactivated derivatives
AYJ52_03695	COG0667	Aldo Keto reductase
AYJ52_03715	COG0583	DNA-binding transcription factor activity
AYJ52_03720	COG2814	Major facilitator Superfamily
AYJ52_03760	COG2801	Transposase and inactivated derivatives
AYJ52_03810	COG2801	Transposase and inactivated derivatives
AYJ52_03845	COG1335	isochorismatase
AYJ52_03855	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_03860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYJ52_03870	COG1113	amino acid transport
AYJ52_03880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYJ52_03895	COG2814	Major facilitator Superfamily
AYJ52_03905	COG0352	thiamine-phosphate diphosphorylase activity
AYJ52_03905	COG0351	phosphomethylpyrimidine kinase
AYJ52_03905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AYJ52_03910	COG0789	Transcriptional regulator
AYJ52_03915	COG0300	oxidoreductase activity
AYJ52_03935	COG1309	transcriptional regulator
AYJ52_03945	COG3706	GGDEF domain
AYJ52_03955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ52_03965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYJ52_03970	COG3162	membrane
AYJ52_03975	COG2198	Histidine kinase
AYJ52_03975	COG0784	Response regulator, receiver
AYJ52_03975	COG2205	protein histidine kinase activity
AYJ52_04000	COG1522	sequence-specific DNA binding
AYJ52_04005	COG1335	isochorismatase
AYJ52_04010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ52_04020	COG0668	transmembrane transport
AYJ52_04025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYJ52_04030	COG1519	Transferase
AYJ52_04035	COG1902	pentaerythritol trinitrate reductase activity
AYJ52_04055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYJ52_04075	COG0426	domain, Protein
AYJ52_04075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ52_04080	COG4774	siderophore transport
AYJ52_04085	COG2119	membrane
AYJ52_04095	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ52_04105	COG4942	peptidase
AYJ52_04120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYJ52_04130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYJ52_04150	COG0189	ligase activity
AYJ52_04175	COG0708	Exodeoxyribonuclease III
AYJ52_04180	COG1393	Belongs to the ArsC family
AYJ52_04195	COG3706	GGDEF domain
AYJ52_04230	COG2351	hydroxyisourate hydrolase activity
AYJ52_04235	COG2233	PERMEase
AYJ52_04245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ52_04255	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AYJ52_04265	COG3150	esterase
AYJ52_04275	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_04310	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_04315	COG3501	Rhs element vgr protein
AYJ52_04325	COG2918	glutathione biosynthetic process
AYJ52_04340	COG2733	membrane
AYJ52_04345	COG0436	Aminotransferase
AYJ52_04350	COG0534	Mate efflux family protein
AYJ52_04455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYJ52_04460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYJ52_04470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AYJ52_04510	COG1280	lysine exporter protein (LysE YggA)
AYJ52_04515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYJ52_04520	COG0546	phosphoglycolate phosphatase activity
AYJ52_04530	COG0010	Belongs to the arginase family
AYJ52_04560	COG2188	Transcriptional regulator
AYJ52_04570	COG0523	cobalamin synthesis protein
AYJ52_04580	COG1113	amino acid transport
AYJ52_04590	COG0625	glutathione transferase activity
AYJ52_04595	COG0346	lactoylglutathione lyase activity
AYJ52_04610	COG1683	Conserved Protein
AYJ52_04620	COG0385	Bile acid
AYJ52_04625	COG1335	isochorismatase
AYJ52_04630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ52_04650	COG2116	formate transmembrane transporter activity
AYJ52_04655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYJ52_04660	COG2133	pyrroloquinoline quinone binding
AYJ52_04665	COG2983	Belongs to the UPF0260 family
AYJ52_04680	COG1194	a g-specific adenine glycosylase
AYJ52_04695	COG2818	Glycosylase
AYJ52_04700	COG1064	alcohol dehydrogenase
AYJ52_04705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ52_04715	COG0583	DNA-binding transcription factor activity
AYJ52_04720	COG0656	L-ascorbic acid biosynthetic process
AYJ52_04725	COG2814	Major facilitator Superfamily
AYJ52_04760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_04775	COG2233	PERMEase
AYJ52_04810	COG0733	neurotransmitter:sodium symporter activity
AYJ52_04820	COG0625	glutathione transferase activity
AYJ52_04850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AYJ52_04855	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AYJ52_04860	COG0596	Alpha beta hydrolase
AYJ52_04885	COG0488	(ABC) transporter
AYJ52_04900	COG0187	DNA topoisomerase II activity
AYJ52_04910	COG0592	DNA-directed DNA polymerase activity
AYJ52_04920	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AYJ52_04935	COG0706	membrane insertase activity
AYJ52_04950	COG1230	cation diffusion facilitator family transporter
AYJ52_04955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYJ52_04970	COG0402	S-adenosylhomocysteine deaminase activity
AYJ52_04980	COG0754	glutathionylspermidine amidase activity
AYJ52_04990	COG0861	Integral membrane protein TerC family
AYJ52_04995	COG0671	phosphoesterase, PA-phosphatase related
AYJ52_05005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYJ52_05025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYJ52_05030	COG2951	lytic endotransglycosylase activity
AYJ52_05060	COG0583	DNA-binding transcription factor activity
AYJ52_05085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYJ52_05125	COG2801	Transposase and inactivated derivatives
AYJ52_05135	COG1047	Peptidyl-prolyl cis-trans
AYJ52_05145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AYJ52_05150	COG0196	riboflavin kinase activity
AYJ52_05160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYJ52_05165	COG1309	transcriptional regulator
AYJ52_05170	COG1116	anion transmembrane transporter activity
AYJ52_05175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ52_05180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ52_05185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ52_05190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ52_05195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYJ52_05195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AYJ52_05210	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_05215	COG0546	phosphoglycolate phosphatase activity
AYJ52_05265	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYJ52_05270	COG0728	peptidoglycan biosynthetic process
AYJ52_05295	COG1596	polysaccharide export
AYJ52_05300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AYJ52_05310	COG1216	Glycosyl transferase, family 2
AYJ52_05330	COG1215	transferase activity, transferring glycosyl groups
AYJ52_05340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AYJ52_05350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYJ52_05355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYJ52_05370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYJ52_05375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYJ52_05385	COG2186	Transcriptional regulator
AYJ52_05395	COG0277	FAD linked oxidase domain protein
AYJ52_05400	COG1448	Aminotransferase
AYJ52_05405	COG1802	Transcriptional regulator
AYJ52_05420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYJ52_05505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYJ52_05515	COG1309	transcriptional regulator
AYJ52_05540	COG0564	pseudouridine synthase activity
AYJ52_05565	COG1522	sequence-specific DNA binding
AYJ52_05580	COG0251	oxidation-reduction process
AYJ52_05585	COG1113	amino acid transport
AYJ52_05590	COG1113	amino acid transport
AYJ52_05610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ52_05615	COG1960	acyl-CoA dehydrogenase activity
AYJ52_05620	COG1024	Enoyl-CoA hydratase
AYJ52_05625	COG1024	Enoyl-CoA hydratase
AYJ52_05630	COG0477	Major facilitator Superfamily
AYJ52_05635	COG3916	Acyl-homoserine-lactone synthase
AYJ52_05645	COG2197	response regulator
AYJ52_05650	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ52_05655	COG1960	acyl-CoA dehydrogenase activity
AYJ52_05660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ52_05660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ52_05660	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AYJ52_05660	COG3321	synthase
AYJ52_05700	COG0271	Belongs to the BolA IbaG family
AYJ52_05710	COG1192	Involved in chromosome partitioning
AYJ52_05725	COG0586	Pfam SNARE associated Golgi protein
AYJ52_05730	COG2259	Doxx family
AYJ52_05735	COG4399	Belongs to the UPF0754 family
AYJ52_05740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ52_05740	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ52_05785	COG0281	malic enzyme
AYJ52_05790	COG2837	iron assimilation
AYJ52_05795	COG1280	lysine exporter protein (LysE YggA)
AYJ52_05800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ52_05805	COG1121	(ABC) transporter
AYJ52_05845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AYJ52_05855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AYJ52_05875	COG0386	Belongs to the glutathione peroxidase family
AYJ52_05890	COG1309	transcriptional regulator
AYJ52_05895	COG0697	spore germination
AYJ52_05905	COG0758	DNA mediated transformation
AYJ52_05940	COG1309	transcriptional regulator
AYJ52_05970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYJ52_05985	COG0655	NAD(P)H dehydrogenase (quinone) activity
AYJ52_06025	COG4452	Inner membrane protein CreD
AYJ52_06030	COG2205	protein histidine kinase activity
AYJ52_06035	COG0745	RESPONSE REGULATOR receiver
AYJ52_06040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYJ52_06050	COG2814	Major facilitator Superfamily
AYJ52_06060	COG1253	flavin adenine dinucleotide binding
AYJ52_06070	COG2860	membrane
AYJ52_06075	COG0477	Major facilitator Superfamily
AYJ52_06085	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ52_06100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYJ52_06120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ52_06125	COG0235	Class ii aldolase
AYJ52_06130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ52_06135	COG0431	NADPH-dependent FMN reductase
AYJ52_06140	COG2801	Transposase and inactivated derivatives
AYJ52_06150	COG0606	chelatase, subunit chli
AYJ52_06205	COG0789	Transcriptional regulator
AYJ52_06215	COG0640	Transcriptional regulator
AYJ52_06225	COG1230	cation diffusion facilitator family transporter
AYJ52_06230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_06240	COG1538	Outer membrane efflux protein
AYJ52_06275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYJ52_06305	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_06325	COG0347	Belongs to the P(II) protein family
AYJ52_06330	COG0004	ammonium transporteR
AYJ52_06340	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ52_06340	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ52_06380	COG0795	lipopolysaccharide-transporting ATPase activity
AYJ52_06385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AYJ52_06390	COG0793	Belongs to the peptidase S41A family
AYJ52_06405	COG2197	response regulator
AYJ52_06415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYJ52_06425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYJ52_06430	COG4974	Belongs to the 'phage' integrase family
AYJ52_06455	COG0772	Belongs to the SEDS family
AYJ52_06460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ52_06465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ52_06495	COG0697	spore germination
AYJ52_06500	COG1538	Outer membrane efflux protein
AYJ52_06520	COG3275	phosphorelay sensor kinase activity
AYJ52_06530	COG0181	hydroxymethylbilane synthase activity
AYJ52_06575	COG1716	ATPase activity
AYJ52_06580	COG0546	phosphoglycolate phosphatase activity
AYJ52_06610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ52_06680	COG2056	Na+-H+ antiporter family
AYJ52_06695	COG0326	Molecular chaperone. Has ATPase activity
AYJ52_06710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AYJ52_06780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYJ52_06785	COG2169	Transcriptional regulator
AYJ52_06785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ52_06815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYJ52_06825	COG0497	DNA recombination
AYJ52_06840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYJ52_06850	COG0237	dephospho-CoA kinase activity
AYJ52_06900	COG0195	Participates in both transcription termination and antitermination
AYJ52_06910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AYJ52_06920	COG2212	antiporter activity
AYJ52_06930	COG0651	ATP synthesis coupled electron transport
AYJ52_06935	COG1006	Multisubunit Na H antiporter MnhC subunit
AYJ52_06940	COG2111	Na H antiporter
AYJ52_06940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYJ52_06955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYJ52_06980	COG2226	methyltransferase
AYJ52_07000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AYJ52_07005	COG1074	ATP-dependent DNA helicase activity
AYJ52_07010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYJ52_07025	COG1185	polyribonucleotide nucleotidyltransferase activity
AYJ52_07030	COG0598	Magnesium transport protein CorA
AYJ52_07035	COG0789	Transcriptional regulator
AYJ52_07040	COG0484	heat shock protein binding
AYJ52_07050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AYJ52_07060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYJ52_07080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ52_07090	COG4535	Mg2 and Co2 transporter CorC
AYJ52_07105	COG0644	oxidoreductase
AYJ52_07105	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYJ52_07115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYJ52_07130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ52_07135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AYJ52_07145	COG0493	'glutamate synthase
AYJ52_07170	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AYJ52_07185	COG0534	Mate efflux family protein
AYJ52_07195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYJ52_07200	COG4221	oxidoreductase activity
AYJ52_07205	COG0583	DNA-binding transcription factor activity
AYJ52_07225	COG1530	ribonuclease E activity
AYJ52_07235	COG0546	phosphoglycolate phosphatase activity
AYJ52_07240	COG2378	regulation of single-species biofilm formation
AYJ52_07245	COG0625	glutathione transferase activity
AYJ52_07255	COG0583	DNA-binding transcription factor activity
AYJ52_07295	COG0583	DNA-binding transcription factor activity
AYJ52_07320	COG0473	3-isopropylmalate dehydrogenase activity
AYJ52_07375	COG1301	dicarboxylic acid transport
AYJ52_07385	COG1560	Kdo2-lipid A biosynthetic process
AYJ52_07400	COG2900	Belongs to the SlyX family
AYJ52_07405	COG0604	alcohol dehydrogenase
AYJ52_07410	COG1733	regulation of RNA biosynthetic process
AYJ52_07435	COG0210	DNA helicase
AYJ52_07440	COG0724	RNA recognition motif
AYJ52_07460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYJ52_07460	COG4651	solute:proton antiporter activity
AYJ52_07465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYJ52_07470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AYJ52_07485	COG0788	formyltetrahydrofolate deformylase activity
AYJ52_07585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ52_07585	COG2813	Specifically methylates the guanine in position
AYJ52_07595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ52_07605	COG4774	siderophore transport
AYJ52_07615	COG0740	serine-type endopeptidase activity
AYJ52_07635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYJ52_07635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYJ52_07640	COG0857	belongs to the CobB CobQ family
AYJ52_07640	COG0280	phosphate acetyltransferase
AYJ52_07645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYJ52_07655	COG0800	Aldolase
AYJ52_07665	COG3265	gluconokinase activity
AYJ52_07670	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_07680	COG2267	carboxylic ester hydrolase activity
AYJ52_07695	COG0793	Belongs to the peptidase S41A family
AYJ52_07730	COG1426	Protein conserved in bacteria
AYJ52_07750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ52_07770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ52_07775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ52_07785	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ52_07790	COG1216	Glycosyl transferase, family 2
AYJ52_07800	COG2986	histidine ammonia-lyase
AYJ52_07840	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_07845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYJ52_07865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYJ52_07875	COG1162	GTPase activity
AYJ52_07880	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AYJ52_07900	COG0577	efflux transmembrane transporter activity
AYJ52_07900	COG1136	(ABC) transporter
AYJ52_07905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_07925	COG0028	Belongs to the TPP enzyme family
AYJ52_07930	COG0440	acetolactate synthase activity
AYJ52_07935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AYJ52_07980	COG2801	Transposase and inactivated derivatives
AYJ52_08100	COG0419	ATPase involved in DNA repair
AYJ52_08105	COG3293	Transposase
AYJ52_08125	COG3328	transposase activity
AYJ52_08165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYJ52_08180	COG0084	hydrolase, TatD family'
AYJ52_08190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYJ52_08195	COG0583	DNA-binding transcription factor activity
AYJ52_08205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ52_08275	COG2217	Heavy metal translocating P-type atpase
AYJ52_08280	COG2205	protein histidine kinase activity
AYJ52_08295	COG2132	Multicopper oxidase
AYJ52_08320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ52_08355	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_08365	COG2814	Major facilitator Superfamily
AYJ52_08375	COG0697	spore germination
AYJ52_08380	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYJ52_08385	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYJ52_08390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYJ52_08405	COG3622	Belongs to the hyi family
AYJ52_08410	COG2084	Dehydrogenase
AYJ52_08415	COG1024	Enoyl-CoA hydratase
AYJ52_08420	COG2205	protein histidine kinase activity
AYJ52_08420	COG0784	Response regulator, receiver
AYJ52_08420	COG5002	protein histidine kinase activity
AYJ52_08425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYJ52_08440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYJ52_08450	COG3956	TIGRFAM MazG family protein
AYJ52_08455	COG1555	photosystem II stabilization
AYJ52_08460	COG0617	tRNA 3'-terminal CCA addition
AYJ52_08465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYJ52_08485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYJ52_08490	COG3028	Belongs to the UPF0307 family
AYJ52_08495	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ52_08510	COG0625	glutathione transferase activity
AYJ52_08530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AYJ52_08535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYJ52_08560	COG0072	phenylalanine-tRNA ligase activity
AYJ52_08585	COG0248	Ppx GppA phosphatase
AYJ52_08595	COG0037	tRNA processing
AYJ52_08635	COG1764	response to oxidative stress
AYJ52_08640	COG1846	Transcriptional regulator
AYJ52_08650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYJ52_08710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYJ52_08715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AYJ52_08720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYJ52_08780	COG1214	PFAM Peptidase M22, glycoprotease
AYJ52_08795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AYJ52_08805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYJ52_08810	COG0561	phosphatase activity
AYJ52_08820	COG2132	Multicopper oxidase
AYJ52_08840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ52_08845	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYJ52_08850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AYJ52_08880	COG1063	alcohol dehydrogenase
AYJ52_08885	COG0583	DNA-binding transcription factor activity
AYJ52_08890	COG1960	acyl-CoA dehydrogenase activity
AYJ52_08895	COG2814	Major facilitator Superfamily
AYJ52_08900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYJ52_08910	COG1309	transcriptional regulator
AYJ52_08925	COG1053	succinate dehydrogenase
AYJ52_08930	COG0583	DNA-binding transcription factor activity
AYJ52_08945	COG0583	DNA-binding transcription factor activity
AYJ52_08975	COG1473	amidohydrolase
AYJ52_08995	COG0583	DNA-binding transcription factor activity
AYJ52_09005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AYJ52_09010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ52_09025	COG1538	Outer membrane efflux protein
AYJ52_09055	COG0438	transferase activity, transferring glycosyl groups
AYJ52_09060	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_09070	COG0110	maltose O-acetyltransferase activity
AYJ52_09090	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_09100	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_09105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ52_09115	COG0745	RESPONSE REGULATOR receiver
AYJ52_09120	COG2205	protein histidine kinase activity
AYJ52_09130	COG2199	diguanylate cyclase activity
AYJ52_09155	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYJ52_09185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYJ52_09190	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ52_09210	COG0583	DNA-binding transcription factor activity
AYJ52_09230	COG0668	transmembrane transport
AYJ52_09235	COG2081	HI0933 family
AYJ52_09240	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AYJ52_09275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ52_09275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ52_09285	COG0489	protein tyrosine kinase activity
AYJ52_09290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYJ52_09340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ52_09350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYJ52_09365	COG0730	response to heat
AYJ52_09375	COG1196	nuclear chromosome segregation
AYJ52_09395	COG2223	nitrite transmembrane transporter activity
AYJ52_09400	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYJ52_09410	COG2226	methyltransferase
AYJ52_09410	COG0596	Alpha beta hydrolase
AYJ52_09410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ52_09425	COG4106	trans-aconitate 2-methyltransferase activity
AYJ52_09440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AYJ52_09445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AYJ52_09450	COG0009	L-threonylcarbamoyladenylate synthase
AYJ52_09455	COG3101	peptidyl-lysine hydroxylation
AYJ52_09460	COG1399	metal-binding, possibly nucleic acid-binding protein
AYJ52_09475	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_09485	COG1652	LysM domain
AYJ52_09490	COG0351	phosphomethylpyrimidine kinase
AYJ52_09490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AYJ52_09490	COG0352	thiamine-phosphate diphosphorylase activity
AYJ52_09500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYJ52_09530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYJ52_09560	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AYJ52_09575	COG0358	DNA primase activity
AYJ52_09610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYJ52_09630	COG0583	DNA-binding transcription factor activity
AYJ52_09635	COG0473	3-isopropylmalate dehydrogenase activity
AYJ52_09650	COG4638	Rieske (2fe-2S)
AYJ52_09655	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_09675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AYJ52_09675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYJ52_09700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AYJ52_09710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AYJ52_09715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ52_09730	COG0456	acetyltransferase
AYJ52_09740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AYJ52_09745	COG0492	ferredoxin-NADP+ reductase activity
AYJ52_09750	COG1674	ftsk spoiiie
AYJ52_09755	COG1280	lysine exporter protein (LysE YggA)
AYJ52_09770	COG2894	cell division
AYJ52_09785	COG0204	Acyl-transferase
AYJ52_09790	COG2885	chlorophyll binding
AYJ52_09795	COG0210	DNA helicase
AYJ52_09805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYJ52_09820	COG0121	glutamine amidotransferase
AYJ52_09835	COG2914	Belongs to the UPF0125 (RnfH) family
AYJ52_09840	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ52_09845	COG0735	belongs to the Fur family
AYJ52_09870	COG0420	3'-5' exonuclease activity
AYJ52_09890	COG1090	epimerase
AYJ52_09905	COG2050	protein possibly involved in aromatic compounds catabolism
AYJ52_09915	COG2814	Major facilitator Superfamily
AYJ52_09920	COG0405	Gamma-glutamyltransferase
AYJ52_09930	COG1401	restriction endodeoxyribonuclease activity
AYJ52_09985	COG1595	DNA-templated transcription, initiation
AYJ52_10040	COG0531	amino acid
AYJ52_10045	COG2040	homocysteine
AYJ52_10070	COG1309	transcriptional regulator
AYJ52_10075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ52_10080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ52_10090	COG1607	acyl-coa hydrolase
AYJ52_10100	COG0523	cobalamin synthesis protein
AYJ52_10110	COG4681	YaeQ
AYJ52_10120	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_10125	COG0726	polysaccharide deacetylase
AYJ52_10125	COG1649	PFAM Uncharacterised BCR, COG1649
AYJ52_10130	COG1215	transferase activity, transferring glycosyl groups
AYJ52_10140	COG1024	Enoyl-CoA hydratase
AYJ52_10155	COG1414	Transcriptional regulator
AYJ52_10175	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_10190	COG2271	Major facilitator Superfamily
AYJ52_10200	COG2267	carboxylic ester hydrolase activity
AYJ52_10205	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_10220	COG0028	Belongs to the TPP enzyme family
AYJ52_10230	COG0477	Major facilitator Superfamily
AYJ52_10235	COG0242	peptide deformylase activity
AYJ52_10240	COG2066	Belongs to the glutaminase family
AYJ52_10245	COG2207	Transcriptional regulator
AYJ52_10250	COG2223	nitrite transmembrane transporter activity
AYJ52_10265	COG0583	DNA-binding transcription factor activity
AYJ52_10270	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_10275	COG2271	Major facilitator Superfamily
AYJ52_10280	COG3959	Transketolase, thiamine diphosphate binding domain
AYJ52_10285	COG3958	Transketolase
AYJ52_10300	COG0306	phosphate transporter
AYJ52_10315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AYJ52_10360	COG4181	ATPase activity
AYJ52_10365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYJ52_10390	COG0583	DNA-binding transcription factor activity
AYJ52_10395	COG2267	carboxylic ester hydrolase activity
AYJ52_10400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ52_10405	COG1773	rubredoxin
AYJ52_10450	COG2851	Citrate transporter
AYJ52_10455	COG1253	flavin adenine dinucleotide binding
AYJ52_10470	COG3015	lipoprotein NlpE involved in copper resistance
AYJ52_10495	COG0804	urea catabolic process
AYJ52_10505	COG0830	nickel cation binding
AYJ52_10520	COG0742	ribosomal rna small subunit methyltransferase
AYJ52_10525	COG0768	penicillin binding
AYJ52_10545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYJ52_10550	COG2878	Part of a membrane complex involved in electron transport
AYJ52_10555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ52_10565	COG3384	dioxygenase
AYJ52_10580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYJ52_10615	COG0006	proline dipeptidase activity
AYJ52_10620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ52_10625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ52_10635	COG0789	Transcriptional regulator
AYJ52_10645	COG1279	arginine transmembrane transporter activity
AYJ52_10650	COG0583	DNA-binding transcription factor activity
AYJ52_10690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYJ52_10695	COG1388	LysM domain
AYJ52_10695	COG0741	lytic transglycosylase activity
AYJ52_10700	COG4166	transmembrane transport
AYJ52_10705	COG4174	ABC transporter (Permease)
AYJ52_10710	COG4239	(ABC) transporter, permease
AYJ52_10715	COG4172	Belongs to the ABC transporter superfamily
AYJ52_10750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYJ52_10760	COG5001	Diguanylate cyclase
AYJ52_10760	COG4251	negative regulation of phosphorylation
AYJ52_10760	COG3706	GGDEF domain
AYJ52_10760	COG2203	Gaf domain
AYJ52_10770	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ52_10770	COG1902	pentaerythritol trinitrate reductase activity
AYJ52_10790	COG3293	Transposase
AYJ52_10805	COG4269	membrane
AYJ52_10815	COG2801	Transposase and inactivated derivatives
AYJ52_10835	COG1113	amino acid transport
AYJ52_10845	COG0531	amino acid
AYJ52_10865	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_10885	COG1113	amino acid transport
AYJ52_10890	COG2831	hemolysin activation secretion protein
AYJ52_10900	COG2801	Transposase and inactivated derivatives
AYJ52_10930	COG0697	spore germination
AYJ52_10935	COG2721	sulfolactate sulfo-lyase activity
AYJ52_10940	COG2271	Major facilitator Superfamily
AYJ52_10945	COG4948	Mandelate Racemase Muconate Lactonizing
AYJ52_10955	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_10960	COG2186	Transcriptional regulator
AYJ52_10985	COG1960	acyl-CoA dehydrogenase activity
AYJ52_10995	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_11000	COG1024	Enoyl-CoA hydratase
AYJ52_11005	COG2814	Major facilitator Superfamily
AYJ52_11020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYJ52_11035	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AYJ52_11055	COG1944	ATP diphosphatase activity
AYJ52_11085	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AYJ52_11090	COG2072	flavoprotein involved in K transport
AYJ52_11105	COG1309	transcriptional regulator
AYJ52_11110	COG1741	Belongs to the pirin family
AYJ52_11120	COG2252	PERMEase
AYJ52_11125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AYJ52_11130	COG3038	cytochrome b561
AYJ52_11140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYJ52_11160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYJ52_11175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AYJ52_11190	COG0667	Aldo Keto reductase
AYJ52_11200	COG1765	OsmC-like protein
AYJ52_11215	COG0542	response to heat
AYJ52_11250	COG2885	chlorophyll binding
AYJ52_11260	COG0625	glutathione transferase activity
AYJ52_11270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AYJ52_11290	COG3634	alkyl hydroperoxide reductase activity
AYJ52_11310	COG0450	alkyl hydroperoxide reductase
AYJ52_11315	COG1643	Atp-dependent helicase
AYJ52_11330	COG2814	Major facilitator Superfamily
AYJ52_11335	COG3135	benzoate transporter
AYJ52_11340	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_11345	COG0543	2 iron, 2 sulfur cluster binding
AYJ52_11345	COG0633	Ferredoxin
AYJ52_11350	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AYJ52_11355	COG4638	Rieske (2fe-2S)
AYJ52_11360	COG0583	DNA-binding transcription factor activity
AYJ52_11370	COG2871	sodium ion transport
AYJ52_11450	COG1570	exodeoxyribonuclease VII activity
AYJ52_11485	COG1280	lysine exporter protein (LysE YggA)
AYJ52_11490	COG1560	Kdo2-lipid A biosynthetic process
AYJ52_11495	COG1278	Cold shock
AYJ52_11515	COG1011	Hydrolase
AYJ52_11520	COG2226	methyltransferase
AYJ52_11530	COG1309	transcriptional regulator
AYJ52_11570	COG0668	transmembrane transport
AYJ52_11590	COG2814	Major facilitator Superfamily
AYJ52_11595	COG1733	regulation of RNA biosynthetic process
AYJ52_11625	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AYJ52_11630	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_11655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AYJ52_11665	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYJ52_11670	COG1137	ATPase activity
AYJ52_11675	COG1538	Outer membrane efflux protein
AYJ52_11695	COG2801	Transposase and inactivated derivatives
AYJ52_11725	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYJ52_11740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYJ52_11755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYJ52_11760	COG0531	amino acid
AYJ52_11765	COG1522	sequence-specific DNA binding
AYJ52_11795	COG1278	Cold shock
AYJ52_11805	COG2801	Transposase and inactivated derivatives
AYJ52_11820	COG2801	Transposase and inactivated derivatives
AYJ52_11830	COG2801	Transposase and inactivated derivatives
AYJ52_11845	COG0753	catalase activity
AYJ52_11850	COG3038	cytochrome b561
AYJ52_11865	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_11885	COG1051	belongs to the nudix hydrolase family
AYJ52_11895	COG2801	Transposase and inactivated derivatives
AYJ52_11910	COG2801	Transposase and inactivated derivatives
AYJ52_11920	COG2801	Transposase and inactivated derivatives
AYJ52_11945	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ52_11950	COG1063	alcohol dehydrogenase
AYJ52_11965	COG0439	Biotin carboxylase
AYJ52_11970	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYJ52_11975	COG1733	regulation of RNA biosynthetic process
AYJ52_11980	COG0864	Transcriptional regulator
AYJ52_11990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ52_11995	COG1116	anion transmembrane transporter activity
AYJ52_12025	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_12055	COG2885	chlorophyll binding
AYJ52_12095	COG0583	DNA-binding transcription factor activity
AYJ52_12100	COG0666	response to abiotic stimulus
AYJ52_12105	COG0590	tRNA wobble adenosine to inosine editing
AYJ52_12110	COG2807	transmembrane transport
AYJ52_12130	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYJ52_12140	COG0789	Transcriptional regulator
AYJ52_12155	COG1760	l-serine dehydratase
AYJ52_12160	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_12160	COG2030	dehydratase
AYJ52_12165	COG3396	Phenylacetate-CoA oxygenase
AYJ52_12170	COG3460	Phenylacetate-CoA oxygenase
AYJ52_12175	COG3396	Phenylacetate-CoA oxygenase
AYJ52_12180	COG2151	metal-sulfur cluster biosynthetic enzyme
AYJ52_12185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYJ52_12190	COG1024	Enoyl-CoA hydratase
AYJ52_12195	COG1024	Enoyl-CoA hydratase
AYJ52_12200	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ52_12205	COG0183	Belongs to the thiolase family
AYJ52_12210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AYJ52_12215	COG3327	negative regulation of DNA-templated transcription, initiation
AYJ52_12225	COG2050	protein possibly involved in aromatic compounds catabolism
AYJ52_12240	COG1309	transcriptional regulator
AYJ52_12245	COG0583	DNA-binding transcription factor activity
AYJ52_12255	COG1414	Transcriptional regulator
AYJ52_12260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ52_12275	COG1840	ABC-type Fe3 transport system, periplasmic component
AYJ52_12280	COG3842	ATPase activity
AYJ52_12295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AYJ52_12300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYJ52_12305	COG2814	Major facilitator Superfamily
AYJ52_12310	COG1960	acyl-CoA dehydrogenase activity
AYJ52_12315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYJ52_12325	COG1024	Enoyl-CoA hydratase
AYJ52_12335	COG2814	Major facilitator Superfamily
AYJ52_12345	COG0183	Belongs to the thiolase family
AYJ52_12350	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ52_12355	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_12360	COG1024	Enoyl-CoA hydratase
AYJ52_12365	COG1960	acyl-CoA dehydrogenase activity
AYJ52_12370	COG2814	Major facilitator Superfamily
AYJ52_12375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYJ52_12380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYJ52_12390	COG2814	Major facilitator Superfamily
AYJ52_12400	COG1960	acyl-CoA dehydrogenase activity
AYJ52_12415	COG0583	DNA-binding transcription factor activity
AYJ52_12430	COG1024	Enoyl-CoA hydratase
AYJ52_12435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYJ52_12440	COG1960	acyl-CoA dehydrogenase activity
AYJ52_12445	COG1309	transcriptional regulator
AYJ52_12450	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ52_12465	COG2814	Major facilitator Superfamily
AYJ52_12475	COG0583	DNA-binding transcription factor activity
AYJ52_12505	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_12525	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_12545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYJ52_12565	COG2205	protein histidine kinase activity
AYJ52_12565	COG0784	Response regulator, receiver
AYJ52_12580	COG0765	amino acid transport
AYJ52_12585	COG0765	amino acid transport
AYJ52_12590	COG1126	abc transporter atp-binding protein
AYJ52_12595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ52_12600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ52_12610	COG1280	lysine exporter protein (LysE YggA)
AYJ52_12615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYJ52_12620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYJ52_12625	COG1045	serine acetyltransferase
AYJ52_12635	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_12640	COG0583	DNA-binding transcription factor activity
AYJ52_12645	COG0625	glutathione transferase activity
AYJ52_12650	COG0625	glutathione transferase activity
AYJ52_12655	COG0583	DNA-binding transcription factor activity
AYJ52_12665	COG1346	cytolysis
AYJ52_12685	COG2814	Major facilitator Superfamily
AYJ52_12695	COG0583	DNA-binding transcription factor activity
AYJ52_12705	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AYJ52_12710	COG3052	prosthetic group binding
AYJ52_12730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYJ52_12750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ52_12755	COG1294	oxidase, subunit
AYJ52_12760	COG1271	oxidase subunit
AYJ52_12780	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_12785	COG0477	Major facilitator Superfamily
AYJ52_12795	COG4521	taurine ABC transporter
AYJ52_12800	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AYJ52_12805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ52_12810	COG2175	clavaminate synthase activity
AYJ52_12820	COG1953	Uracil, thiamine, allantoin
AYJ52_12830	COG0583	DNA-binding transcription factor activity
AYJ52_12840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AYJ52_12850	COG0640	Transcriptional regulator
AYJ52_12860	COG0798	PFAM Bile acid sodium symporter
AYJ52_12865	COG0431	NADPH-dependent FMN reductase
AYJ52_12870	COG0583	DNA-binding transcription factor activity
AYJ52_12885	COG3634	alkyl hydroperoxide reductase activity
AYJ52_12920	COG1301	dicarboxylic acid transport
AYJ52_12925	COG0436	Aminotransferase
AYJ52_12935	COG0386	Belongs to the glutathione peroxidase family
AYJ52_12940	COG2207	Transcriptional regulator
AYJ52_12940	COG1917	Cupin 2, conserved barrel domain protein
AYJ52_12975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYJ52_13005	COG2801	Transposase and inactivated derivatives
AYJ52_13010	COG0012	GTP binding
AYJ52_13015	COG2011	ABC-type metal ion transport system permease component
AYJ52_13020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYJ52_13030	COG1464	Belongs to the NlpA lipoprotein family
AYJ52_13060	COG0765	amino acid transport
AYJ52_13065	COG0765	amino acid transport
AYJ52_13070	COG1126	abc transporter atp-binding protein
AYJ52_13080	COG1522	sequence-specific DNA binding
AYJ52_13095	COG1309	transcriptional regulator
AYJ52_13110	COG0583	DNA-binding transcription factor activity
AYJ52_13120	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_13130	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYJ52_13140	COG0697	spore germination
AYJ52_13145	COG0583	DNA-binding transcription factor activity
AYJ52_13180	COG3539	Fimbrial protein
AYJ52_13195	COG2801	Transposase and inactivated derivatives
AYJ52_13215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYJ52_13215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYJ52_13260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYJ52_13270	COG2353	YceI-like domain
AYJ52_13280	COG3698	Phosphodiester glycosidase
AYJ52_13295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AYJ52_13300	COG0506	proline dehydrogenase activity
AYJ52_13300	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYJ52_13300	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYJ52_13310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYJ52_13315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYJ52_13335	COG1132	(ABC) transporter
AYJ52_13340	COG3122	Protein conserved in bacteria
AYJ52_13345	COG3619	membrane
AYJ52_13355	COG0640	Transcriptional regulator
AYJ52_13365	COG2850	peptidyl-arginine hydroxylation
AYJ52_13370	COG0424	maF-like protein
AYJ52_13395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ52_13405	COG3178	'Phosphotransferase
AYJ52_13410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ52_13420	COG1192	Involved in chromosome partitioning
AYJ52_13425	COG1475	DNA binding
AYJ52_13430	COG0811	peptide transport
AYJ52_13440	COG1132	(ABC) transporter
AYJ52_13445	COG1663	tetraacyldisaccharide 4'-kinase activity
AYJ52_13465	COG0084	hydrolase, TatD family'
AYJ52_13510	COG0590	tRNA wobble adenosine to inosine editing
AYJ52_13530	COG0776	regulation of translation
AYJ52_13545	COG2431	L-lysine efflux transmembrane transporter activity
AYJ52_13560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYJ52_13565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYJ52_13605	COG4166	transmembrane transport
AYJ52_13610	COG0339	signal peptide processing
AYJ52_13615	COG0601	transmembrane transport
AYJ52_13655	COG0702	epimerase
AYJ52_13660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYJ52_13680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYJ52_13710	COG0316	Belongs to the HesB IscA family
AYJ52_13715	COG0822	iron-sulfur transferase activity
AYJ52_13740	COG0776	regulation of translation
AYJ52_13745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ52_13750	COG2207	Transcriptional regulator
AYJ52_13755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ52_13760	COG1960	acyl-CoA dehydrogenase activity
AYJ52_13765	COG1960	acyl-CoA dehydrogenase activity
AYJ52_13780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYJ52_13790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYJ52_13805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AYJ52_13810	COG0406	alpha-ribazole phosphatase activity
AYJ52_13825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYJ52_13830	COG0730	response to heat
AYJ52_13850	COG4773	Receptor
AYJ52_13855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ52_13915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AYJ52_13925	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYJ52_13930	COG0583	DNA-binding transcription factor activity
AYJ52_13955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYJ52_13965	COG0133	tryptophan synthase activity
AYJ52_13985	COG3706	GGDEF domain
AYJ52_14000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYJ52_14005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AYJ52_14010	COG0022	dehydrogenase e1 component
AYJ52_14015	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ52_14020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ52_14030	COG1063	alcohol dehydrogenase
AYJ52_14035	COG3781	membrane
AYJ52_14055	COG0730	response to heat
AYJ52_14070	COG3708	Transcriptional regulator
AYJ52_14070	COG2207	Transcriptional regulator
AYJ52_14075	COG1733	regulation of RNA biosynthetic process
AYJ52_14080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYJ52_14090	COG0477	Major facilitator Superfamily
AYJ52_14100	COG1027	Aspartate ammonia-lyase
AYJ52_14115	COG0583	DNA-binding transcription factor activity
AYJ52_14120	COG0583	DNA-binding transcription factor activity
AYJ52_14125	COG0183	Belongs to the thiolase family
AYJ52_14130	COG2031	fatty acid transporter
AYJ52_14145	COG0583	DNA-binding transcription factor activity
AYJ52_14175	COG2610	gluconate transmembrane transporter activity
AYJ52_14180	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_14185	COG2207	Transcriptional regulator
AYJ52_14200	COG0412	Dienelactone hydrolase
AYJ52_14205	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_14215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ52_14230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYJ52_14230	COG0543	2 iron, 2 sulfur cluster binding
AYJ52_14235	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AYJ52_14240	COG4638	Rieske (2fe-2S)
AYJ52_14250	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYJ52_14255	COG4149	molybdate abc transporter
AYJ52_14260	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ52_14265	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_14270	COG3433	isochorismatase activity
AYJ52_14270	COG1535	isochorismatase
AYJ52_14325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ52_14330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_14335	COG0745	RESPONSE REGULATOR receiver
AYJ52_14340	COG2205	protein histidine kinase activity
AYJ52_14350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ52_14365	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_14375	COG0753	catalase activity
AYJ52_14385	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AYJ52_14410	COG3539	Fimbrial protein
AYJ52_14420	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_14495	COG2801	Transposase and inactivated derivatives
AYJ52_14535	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AYJ52_14585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYJ52_14605	COG1120	ATPase activity
AYJ52_14625	COG2084	Dehydrogenase
AYJ52_14635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ52_14640	COG0583	DNA-binding transcription factor activity
AYJ52_14650	COG0129	dihydroxy-acid dehydratase activity
AYJ52_14655	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_14680	COG2271	Major facilitator Superfamily
AYJ52_14695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ52_14735	COG3210	domain, Protein
AYJ52_14740	COG2831	hemolysin activation secretion protein
AYJ52_14755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYJ52_14760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ52_14785	COG0583	DNA-binding transcription factor activity
AYJ52_14805	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_14820	COG4993	Dehydrogenase
AYJ52_14825	COG0583	DNA-binding transcription factor activity
AYJ52_14835	COG2259	Doxx family
AYJ52_14840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYJ52_14865	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ52_14875	COG1960	acyl-CoA dehydrogenase activity
AYJ52_14885	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_14890	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_14895	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_14900	COG0583	DNA-binding transcription factor activity
AYJ52_14905	COG1309	transcriptional regulator
AYJ52_14935	COG4221	oxidoreductase activity
AYJ52_14940	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ52_14940	COG1902	pentaerythritol trinitrate reductase activity
AYJ52_14955	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_14975	COG2186	Transcriptional regulator
AYJ52_14985	COG0583	DNA-binding transcription factor activity
AYJ52_14990	COG4948	Mandelate Racemase Muconate Lactonizing
AYJ52_14995	COG4829	muconolactone delta-isomerase
AYJ52_15005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYJ52_15010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYJ52_15015	COG0183	Belongs to the thiolase family
AYJ52_15020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ52_15025	COG1012	belongs to the aldehyde dehydrogenase family
AYJ52_15035	COG3733	amine oxidase
AYJ52_15045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ52_15055	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_15065	COG4638	Rieske (2fe-2S)
AYJ52_15085	COG0154	amidase activity
AYJ52_15095	COG2814	Major facilitator Superfamily
AYJ52_15125	COG0583	DNA-binding transcription factor activity
AYJ52_15130	COG1414	Transcriptional regulator
AYJ52_15145	COG2391	methyltransferase activity
AYJ52_15150	COG2801	Transposase and inactivated derivatives
AYJ52_15165	COG4993	Dehydrogenase
AYJ52_15170	COG3659	wide pore channel activity
AYJ52_15175	COG3420	alginic acid biosynthetic process
AYJ52_15180	COG0710	3-dehydroquinate dehydratase activity
AYJ52_15185	COG3485	protocatechuate 3,4-dioxygenase
AYJ52_15190	COG3485	protocatechuate 3,4-dioxygenase
AYJ52_15195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYJ52_15200	COG2271	Major facilitator Superfamily
AYJ52_15205	COG0596	Alpha beta hydrolase
AYJ52_15210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYJ52_15215	COG0183	Belongs to the thiolase family
AYJ52_15220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYJ52_15225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYJ52_15235	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AYJ52_15240	COG2801	Transposase and inactivated derivatives
AYJ52_15250	COG4773	Receptor
AYJ52_15260	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_15265	COG2323	membrane
AYJ52_15270	COG0148	phosphopyruvate hydratase activity
AYJ52_15310	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ52_15310	COG1902	pentaerythritol trinitrate reductase activity
AYJ52_15325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYJ52_15335	COG0542	response to heat
AYJ52_15340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AYJ52_15370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYJ52_15375	COG0569	domain protein
AYJ52_15380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ52_15395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ52_15405	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYJ52_15420	COG1294	oxidase, subunit
AYJ52_15425	COG4890	Cyd operon protein YbgT
AYJ52_15440	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AYJ52_15450	COG0552	protein localization to endoplasmic reticulum
AYJ52_15475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYJ52_15475	COG0517	IMP dehydrogenase activity
AYJ52_15480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYJ52_15485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYJ52_15495	COG0583	DNA-binding transcription factor activity
AYJ52_15500	COG0024	Methionine aminopeptidase
AYJ52_15510	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AYJ52_15530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYJ52_15530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYJ52_15535	COG1105	Belongs to the carbohydrate kinase PfkB family
AYJ52_15540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYJ52_15540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYJ52_15540	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AYJ52_15575	COG0659	secondary active sulfate transmembrane transporter activity
AYJ52_15595	COG1113	amino acid transport
AYJ52_15605	COG1522	sequence-specific DNA binding
AYJ52_15620	COG1011	Hydrolase
AYJ52_15625	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYJ52_15635	COG2137	regulation of response to DNA damage stimulus
AYJ52_15650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ52_15670	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ52_15685	COG0575	Belongs to the CDS family
AYJ52_15690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYJ52_15710	COG3852	Histidine kinase
AYJ52_15715	COG2204	response regulator
AYJ52_15765	COG0596	Alpha beta hydrolase
AYJ52_15780	COG2801	Transposase and inactivated derivatives
AYJ52_15795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYJ52_15820	COG0697	spore germination
AYJ52_15825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ52_15835	COG0303	'Molybdopterin
AYJ52_15840	COG0315	cyclic pyranopterin monophosphate synthase activity
AYJ52_15840	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYJ52_15855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AYJ52_15860	COG0243	molybdopterin cofactor binding
AYJ52_15870	COG0243	molybdopterin cofactor binding
AYJ52_15875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ52_15880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ52_15880	COG2146	nitrite reductase [NAD(P)H] activity
AYJ52_15895	COG1116	anion transmembrane transporter activity
AYJ52_15895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ52_15900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYJ52_15905	COG2423	ornithine cyclodeaminase activity
AYJ52_15910	COG4264	IucA IucC family
AYJ52_15920	COG4264	IucA IucC family
AYJ52_15945	COG0511	ligase activity, forming carbon-carbon bonds
AYJ52_15960	COG2814	Major facilitator Superfamily
AYJ52_15990	COG0069	glutamate synthase activity
AYJ52_16020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYJ52_16045	COG1454	alcohol dehydrogenase
AYJ52_16050	COG0824	Thioesterase
AYJ52_16060	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYJ52_16100	COG0183	Belongs to the thiolase family
AYJ52_16110	COG0583	DNA-binding transcription factor activity
AYJ52_16125	COG1522	sequence-specific DNA binding
AYJ52_16130	COG3135	benzoate transporter
AYJ52_16145	COG0589	response to stress
AYJ52_16150	COG0488	(ABC) transporter
AYJ52_16175	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_16180	COG0583	DNA-binding transcription factor activity
AYJ52_16200	COG3772	lysozyme
AYJ52_16230	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_16260	COG4774	siderophore transport
AYJ52_16265	COG4772	TonB-dependent receptor
AYJ52_16270	COG2801	Transposase and inactivated derivatives
AYJ52_16285	COG1605	Chorismate mutase
AYJ52_16325	COG0308	aminopeptidase N
AYJ52_16350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYJ52_16355	COG1454	alcohol dehydrogenase
AYJ52_16375	COG0531	amino acid
AYJ52_16380	COG4303	Ethanolamine ammonia lyase large subunit
AYJ52_16385	COG4302	ethanolamine ammonia-lyase activity
AYJ52_16390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ52_16390	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ52_16395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ52_16405	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ52_16420	COG0697	spore germination
AYJ52_16425	COG1923	regulation of RNA biosynthetic process
AYJ52_16435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYJ52_16440	COG0802	atpase or kinase
AYJ52_16460	COG1187	pseudouridine synthase activity
AYJ52_16475	COG0583	DNA-binding transcription factor activity
AYJ52_16490	COG2814	Major facilitator Superfamily
AYJ52_16495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYJ52_16525	COG0729	surface antigen
AYJ52_16530	COG0477	Major facilitator Superfamily
AYJ52_16545	COG0174	glutamine synthetase
AYJ52_16550	COG0745	RESPONSE REGULATOR receiver
AYJ52_16555	COG2205	protein histidine kinase activity
AYJ52_16565	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AYJ52_16570	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AYJ52_16580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYJ52_16595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ52_16600	COG1960	acyl-CoA dehydrogenase activity
AYJ52_16615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ52_16620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ52_16625	COG2890	protein-(glutamine-N5) methyltransferase activity
AYJ52_16655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ52_16665	COG3658	cytochrome
AYJ52_16670	COG1215	transferase activity, transferring glycosyl groups
AYJ52_16675	COG1649	PFAM Uncharacterised BCR, COG1649
AYJ52_16675	COG0726	polysaccharide deacetylase
AYJ52_16685	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_16710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYJ52_16715	COG1845	cytochrome c oxidase, subunit III
AYJ52_16720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYJ52_16745	COG0305	Participates in initiation and elongation during chromosome replication
AYJ52_16750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYJ52_16760	COG1305	Transglutaminase-like
AYJ52_16770	COG2308	Evidence 4 Homologs of previously reported genes of
AYJ52_16800	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AYJ52_16810	COG0151	Belongs to the GarS family
AYJ52_16820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYJ52_16825	COG2011	ABC-type metal ion transport system permease component
AYJ52_16830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ52_16840	COG1301	dicarboxylic acid transport
AYJ52_16885	COG2855	membrane
AYJ52_16900	COG2814	Major facilitator Superfamily
AYJ52_16905	COG3246	L-lysine catabolic process to acetate
AYJ52_16910	COG2175	clavaminate synthase activity
AYJ52_16920	COG1794	racemase activity, acting on amino acids and derivatives
AYJ52_16935	COG0745	RESPONSE REGULATOR receiver
AYJ52_16940	COG0642	Histidine kinase
AYJ52_16955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ52_16995	COG2351	hydroxyisourate hydrolase activity
AYJ52_17005	COG3008	intermembrane lipid transfer
AYJ52_17005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYJ52_17010	COG2995	paraquat-inducible protein a
AYJ52_17020	COG2985	domain, Protein
AYJ52_17030	COG1309	transcriptional regulator
AYJ52_17085	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_17095	COG0786	glutamate:sodium symporter activity
AYJ52_17100	COG3243	poly(R)-hydroxyalkanoic acid synthase
AYJ52_17115	COG1278	Cold shock
AYJ52_17165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYJ52_17170	COG1610	YqeY-like protein
AYJ52_17175	COG4783	chaperone-mediated protein folding
AYJ52_17200	COG1286	toxin biosynthetic process
AYJ52_17230	COG0778	Nitroreductase
AYJ52_17240	COG0513	Belongs to the DEAD box helicase family
AYJ52_17260	COG2363	Small membrane protein
AYJ52_17290	COG4650	regulator
AYJ52_17295	COG1234	tRNA 3'-trailer cleavage
AYJ52_17300	COG1690	Belongs to the RtcB family
AYJ52_17320	COG2195	Cleaves the N-terminal amino acid of tripeptides
AYJ52_17330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AYJ52_17350	COG1960	acyl-CoA dehydrogenase activity
AYJ52_17355	COG1301	dicarboxylic acid transport
AYJ52_17365	COG3139	Protein of unknown function (DUF1315)
AYJ52_17370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AYJ52_17375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYJ52_17385	COG0494	nUDIX hydrolase
AYJ52_17395	COG0642	Histidine kinase
AYJ52_17400	COG0745	RESPONSE REGULATOR receiver
AYJ52_17420	COG1720	tRNA m6t6A37 methyltransferase activity
AYJ52_17430	COG0384	phenazine biosynthesis protein PhzF
AYJ52_17435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ52_17445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYJ52_17455	COG4598	ABC transporter
AYJ52_17460	COG4160	amino acid transport
AYJ52_17465	COG4215	(ABC) transporter
AYJ52_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ52_17480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ52_17490	COG1538	Outer membrane efflux protein
AYJ52_17520	COG1131	(ABC) transporter
AYJ52_17525	COG0842	Transport permease protein
AYJ52_17540	COG0772	Belongs to the SEDS family
AYJ52_17545	COG2951	lytic endotransglycosylase activity
AYJ52_17565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYJ52_17570	COG2207	Transcriptional regulator
AYJ52_17585	COG0052	Belongs to the universal ribosomal protein uS2 family
AYJ52_17590	COG0024	Methionine aminopeptidase
AYJ52_17600	COG2223	nitrite transmembrane transporter activity
AYJ52_17610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ52_17615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYJ52_17620	COG1960	acyl-CoA dehydrogenase activity
AYJ52_17635	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AYJ52_17640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYJ52_17645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYJ52_17665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYJ52_17670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYJ52_17675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYJ52_17710	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AYJ52_17725	COG3104	oligopeptide transport
AYJ52_17735	COG0512	Glutamine amidotransferase of anthranilate synthase
AYJ52_17740	COG0308	aminopeptidase N
AYJ52_17770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYJ52_17780	COG0302	gtp cyclohydrolase
AYJ52_17800	COG3739	integral membrane protein
AYJ52_17815	COG1169	isochorismate synthase
AYJ52_17825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AYJ52_17835	COG1132	(ABC) transporter
AYJ52_17845	COG1535	isochorismatase
AYJ52_17845	COG3433	isochorismatase activity
AYJ52_17850	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYJ52_17855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYJ52_17865	COG4774	siderophore transport
AYJ52_17870	COG4607	ABC-type enterochelin transport system periplasmic component
AYJ52_17875	COG4604	ABC transporter, ATP-binding protein
AYJ52_17880	COG4605	iron ion homeostasis
AYJ52_17885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ52_17890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYJ52_17905	COG1741	Belongs to the pirin family
AYJ52_17915	COG2964	Protein conserved in bacteria
AYJ52_17925	COG2423	ornithine cyclodeaminase activity
AYJ52_17960	COG4829	muconolactone delta-isomerase
AYJ52_17965	COG0183	Belongs to the thiolase family
AYJ52_17970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYJ52_17975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYJ52_18000	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ52_18010	COG1301	dicarboxylic acid transport
AYJ52_18020	COG2801	Transposase and inactivated derivatives
AYJ52_18075	COG2026	Addiction module toxin, RelE StbE family
AYJ52_18115	COG2879	small protein
AYJ52_18120	COG1966	Carbon starvation protein
AYJ52_18125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AYJ52_18160	COG2211	Major facilitator Superfamily
AYJ52_18165	COG1067	ATP-dependent peptidase activity
AYJ52_18170	COG0583	DNA-binding transcription factor activity
AYJ52_18195	COG1686	Belongs to the peptidase S11 family
AYJ52_18200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYJ52_18235	COG0616	signal peptide processing
AYJ52_18240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYJ52_18250	COG0573	inorganic phosphate transmembrane transporter activity
AYJ52_18255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYJ52_18270	COG1113	amino acid transport
AYJ52_18275	COG3961	Belongs to the TPP enzyme family
AYJ52_18280	COG1522	sequence-specific DNA binding
AYJ52_18290	COG0076	glutamate decarboxylase activity
AYJ52_18295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYJ52_18310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYJ52_18345	COG0352	thiamine-phosphate diphosphorylase activity
AYJ52_18370	COG0612	Peptidase, M16
AYJ52_18385	COG0583	DNA-binding transcription factor activity
AYJ52_18390	COG0477	Major facilitator Superfamily
AYJ52_18395	COG2801	Transposase and inactivated derivatives
AYJ52_18410	COG1187	pseudouridine synthase activity
AYJ52_18425	COG1686	Belongs to the peptidase S11 family
AYJ52_18430	COG1252	NADH dehydrogenase
AYJ52_18440	COG0415	Belongs to the DNA photolyase family
AYJ52_18455	COG1215	transferase activity, transferring glycosyl groups
AYJ52_18470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AYJ52_18485	COG2070	2-Nitropropane dioxygenase
AYJ52_18530	COG2962	Rard protein
AYJ52_18540	COG0556	nucleotide-excision repair
AYJ52_18585	COG4221	oxidoreductase activity
AYJ52_18595	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYJ52_18600	COG1381	Involved in DNA repair and RecF pathway recombination
AYJ52_18610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AYJ52_18615	COG0571	ribonuclease III activity
AYJ52_18625	COG0681	Belongs to the peptidase S26 family
AYJ52_18630	COG0481	GTPase activity
AYJ52_18640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYJ52_18660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYJ52_18665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYJ52_18670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AYJ52_18680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYJ52_18685	COG4208	sulfate ABC transporter
AYJ52_18690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AYJ52_18695	COG0583	DNA-binding transcription factor activity
AYJ52_18700	COG4625	pathogenesis
AYJ52_18715	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AYJ52_18730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ52_18745	COG1056	cytidyltransferase-related domain
AYJ52_18745	COG1051	belongs to the nudix hydrolase family
AYJ52_18750	COG1024	Enoyl-CoA hydratase
AYJ52_18755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYJ52_18770	COG2814	Major facilitator Superfamily
AYJ52_18775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYJ52_18775	COG0047	phosphoribosylformylglycinamidine synthase activity
AYJ52_18795	COG1473	amidohydrolase
AYJ52_18800	COG0824	Thioesterase
AYJ52_18820	COG0823	Involved in the tonB-independent uptake of proteins
AYJ52_18860	COG3316	Transposase and inactivated derivatives
AYJ52_18870	COG2801	Transposase and inactivated derivatives
AYJ52_18885	COG1660	Displays ATPase and GTPase activities
AYJ52_18950	COG0739	heme binding
AYJ52_18970	COG1475	DNA binding
AYJ52_19030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYJ52_19135	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AYJ52_19140	COG3293	Transposase
AYJ52_19195	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_19215	COG0673	inositol 2-dehydrogenase activity
AYJ52_19250	COG2826	transposase and inactivated derivatives, IS30 family
AYJ52_19325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYJ52_19345	COG2184	nucleotidyltransferase activity
AYJ52_19355	COG4974	Belongs to the 'phage' integrase family
AYJ52_19445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYJ52_19450	COG0501	Belongs to the peptidase M48B family
AYJ52_19550	COG3173	Aminoglycoside phosphotransferase
AYJ52_19565	COG2205	protein histidine kinase activity
AYJ52_19570	COG0745	RESPONSE REGULATOR receiver
AYJ52_19580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ52_19585	COG1538	Outer membrane efflux protein
AYJ52_19595	COG5002	protein histidine kinase activity
AYJ52_19600	COG3316	Transposase and inactivated derivatives
AYJ52_19655	COG3316	Transposase and inactivated derivatives
AYJ52_19670	COG3657	addiction module killer protein
AYJ52_19675	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYJ52_19680	COG0659	secondary active sulfate transmembrane transporter activity
AYJ52_19740	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
