locus-tag	class	description
DDE02_00015	COG0625	glutathione transferase activity
DDE02_00025	COG0733	neurotransmitter:sodium symporter activity
DDE02_00065	COG2233	PERMEase
DDE02_00080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_00115	COG2814	Major facilitator Superfamily
DDE02_00120	COG0656	L-ascorbic acid biosynthetic process
DDE02_00125	COG0583	DNA-binding transcription factor activity
DDE02_00140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_00145	COG1064	alcohol dehydrogenase
DDE02_00150	COG2818	Glycosylase
DDE02_00165	COG1194	a g-specific adenine glycosylase
DDE02_00180	COG5487	UPF0391 membrane protein
DDE02_00185	COG2983	Belongs to the UPF0260 family
DDE02_00190	COG2133	pyrroloquinoline quinone binding
DDE02_00195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDE02_00200	COG2116	formate transmembrane transporter activity
DDE02_00220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDE02_00225	COG1335	isochorismatase
DDE02_00230	COG0385	Bile acid
DDE02_00235	COG0534	Mate efflux family protein
DDE02_00240	COG1683	Conserved Protein
DDE02_00255	COG0346	lactoylglutathione lyase activity
DDE02_00260	COG0625	glutathione transferase activity
DDE02_00270	COG1113	amino acid transport
DDE02_00280	COG0523	cobalamin synthesis protein
DDE02_00290	COG2188	Transcriptional regulator
DDE02_00320	COG0010	Belongs to the arginase family
DDE02_00360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDE02_00370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DDE02_00375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DDE02_00480	COG0534	Mate efflux family protein
DDE02_00485	COG0436	Aminotransferase
DDE02_00490	COG2733	membrane
DDE02_00505	COG2918	glutathione biosynthetic process
DDE02_00550	COG3150	esterase
DDE02_00560	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DDE02_00570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_00580	COG2233	PERMEase
DDE02_00585	COG2351	hydroxyisourate hydrolase activity
DDE02_00620	COG3706	GGDEF domain
DDE02_00635	COG1393	Belongs to the ArsC family
DDE02_00640	COG0708	Exodeoxyribonuclease III
DDE02_00660	COG0189	ligase activity
DDE02_00680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DDE02_00690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DDE02_00705	COG4942	peptidase
DDE02_00715	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDE02_00725	COG2119	membrane
DDE02_00730	COG4774	siderophore transport
DDE02_00735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDE02_00735	COG0426	domain, Protein
DDE02_00755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DDE02_00775	COG1902	pentaerythritol trinitrate reductase activity
DDE02_00780	COG1519	Transferase
DDE02_00785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDE02_00790	COG0668	transmembrane transport
DDE02_00800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDE02_00805	COG1335	isochorismatase
DDE02_00810	COG1522	sequence-specific DNA binding
DDE02_00815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDE02_00835	COG0784	Response regulator, receiver
DDE02_00835	COG2198	Histidine kinase
DDE02_00835	COG2205	protein histidine kinase activity
DDE02_00840	COG3162	membrane
DDE02_00845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDE02_00855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDE02_00880	COG1309	transcriptional regulator
DDE02_00900	COG0300	oxidoreductase activity
DDE02_00905	COG0789	Transcriptional regulator
DDE02_00910	COG0351	phosphomethylpyrimidine kinase
DDE02_00910	COG0352	thiamine-phosphate diphosphorylase activity
DDE02_00910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DDE02_00920	COG2814	Major facilitator Superfamily
DDE02_00935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DDE02_00945	COG1113	amino acid transport
DDE02_00955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDE02_00960	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_00970	COG1335	isochorismatase
DDE02_01065	COG2814	Major facilitator Superfamily
DDE02_01070	COG0583	DNA-binding transcription factor activity
DDE02_01090	COG0667	Aldo Keto reductase
DDE02_01135	COG1733	regulation of RNA biosynthetic process
DDE02_01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDE02_01155	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DDE02_01160	COG2207	Transcriptional regulator
DDE02_01220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DDE02_01235	COG0697	spore germination
DDE02_01260	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDE02_01290	COG0427	acetyl-CoA hydrolase
DDE02_01315	COG0659	secondary active sulfate transmembrane transporter activity
DDE02_01320	COG4221	oxidoreductase activity
DDE02_01325	COG2873	o-acetylhomoserine
DDE02_01330	COG0488	(ABC) transporter
DDE02_01490	COG0582	viral genome integration into host DNA
DDE02_01510	COG0833	amino acid
DDE02_01555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDE02_01560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDE02_01575	COG2226	methyltransferase
DDE02_01625	COG0067	glutamate synthase
DDE02_01625	COG0069	glutamate synthase activity
DDE02_01625	COG0070	glutamate synthase
DDE02_01630	COG0493	'glutamate synthase
DDE02_01640	COG1704	LemA family
DDE02_01645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DDE02_01655	COG4969	Belongs to the N-Me-Phe pilin family
DDE02_01665	COG3307	-O-antigen
DDE02_01690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDE02_01705	COG0194	GDP metabolic process
DDE02_01755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDE02_01765	COG0335	large ribosomal subunit rRNA binding
DDE02_01775	COG5380	lipid catabolic process
DDE02_01780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDE02_01795	COG5006	permease, DMT superfamily
DDE02_01800	COG5006	permease, DMT superfamily
DDE02_01805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDE02_01810	COG0277	FAD linked oxidase domain protein
DDE02_01820	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DDE02_01825	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDE02_01840	COG1289	transmembrane transporter activity
DDE02_01850	COG0628	permease
DDE02_01855	COG1192	Involved in chromosome partitioning
DDE02_01885	COG0833	amino acid
DDE02_01890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDE02_01895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDE02_01905	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_01945	COG0583	DNA-binding transcription factor activity
DDE02_01960	COG5002	protein histidine kinase activity
DDE02_01985	COG0752	glycyl-tRNA synthetase alpha subunit
DDE02_02010	COG0517	IMP dehydrogenase activity
DDE02_02010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DDE02_02010	COG0617	tRNA 3'-terminal CCA addition
DDE02_02015	COG1983	PspC domain protein
DDE02_02025	COG1960	acyl-CoA dehydrogenase activity
DDE02_02040	COG0408	coproporphyrinogen oxidase activity
DDE02_02060	COG0513	Belongs to the DEAD box helicase family
DDE02_02070	COG1127	ABC transporter
DDE02_02075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DDE02_02085	COG2854	intermembrane phospholipid transfer
DDE02_02095	COG0598	Magnesium transport protein CorA
DDE02_02105	COG0494	nUDIX hydrolase
DDE02_02110	COG1040	competence protein
DDE02_02115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DDE02_02130	COG2937	Belongs to the GPAT DAPAT family
DDE02_02135	COG1946	Acyl-CoA thioesterase
DDE02_02140	COG1301	dicarboxylic acid transport
DDE02_02155	COG1959	2 iron, 2 sulfur cluster binding
DDE02_02160	COG1017	nitric oxide dioxygenase activity
DDE02_02160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDE02_02170	COG0433	COG0433 Predicted ATPase
DDE02_02175	COG0626	cystathionine gamma-synthase activity
DDE02_02190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDE02_02195	COG0088	Forms part of the polypeptide exit tunnel
DDE02_02330	COG1960	acyl-CoA dehydrogenase activity
DDE02_02335	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DDE02_02365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DDE02_02370	COG0339	signal peptide processing
DDE02_02375	COG0557	exoribonuclease II activity
DDE02_02425	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDE02_02430	COG1295	ribonuclease BN
DDE02_02465	COG1702	phosphate starvation-inducible protein PhoH
DDE02_02475	COG0739	heme binding
DDE02_02475	COG0741	lytic transglycosylase activity
DDE02_02475	COG1196	nuclear chromosome segregation
DDE02_02505	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DDE02_02510	COG1183	phosphatidylcholine synthase activity
DDE02_02555	COG1960	acyl-CoA dehydrogenase activity
DDE02_02560	COG1309	transcriptional regulator
DDE02_02575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDE02_02580	COG1960	acyl-CoA dehydrogenase activity
DDE02_02620	COG2969	positive regulation of protein catabolic process
DDE02_02625	COG0625	glutathione transferase activity
DDE02_02630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDE02_02635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDE02_02640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DDE02_02645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDE02_02650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DDE02_02670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDE02_02680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDE02_02685	COG1408	metallophosphoesterase
DDE02_02690	COG2885	chlorophyll binding
DDE02_02690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DDE02_02695	COG2199	diguanylate cyclase activity
DDE02_02765	COG1607	acyl-coa hydrolase
DDE02_02800	COG2350	Protein conserved in bacteria
DDE02_02815	COG3781	membrane
DDE02_02825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDE02_02830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDE02_02840	COG1862	Preprotein translocase
DDE02_02875	COG0784	Response regulator, receiver
DDE02_02875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDE02_02875	COG2205	protein histidine kinase activity
DDE02_02875	COG2198	Histidine kinase
DDE02_02880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DDE02_02895	COG0726	polysaccharide deacetylase
DDE02_02910	COG1216	Glycosyl transferase, family 2
DDE02_02960	COG0625	glutathione transferase activity
DDE02_02965	COG0583	DNA-binding transcription factor activity
DDE02_02970	COG1960	acyl-CoA dehydrogenase activity
DDE02_02975	COG1960	acyl-CoA dehydrogenase activity
DDE02_02985	COG2205	protein histidine kinase activity
DDE02_02990	COG0745	RESPONSE REGULATOR receiver
DDE02_03000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DDE02_03020	COG2096	Adenosyltransferase
DDE02_03025	COG4206	TonB-dependent receptor
DDE02_03070	COG0285	dihydrofolate synthase activity
DDE02_03090	COG0450	alkyl hydroperoxide reductase
DDE02_03105	COG0477	Major facilitator Superfamily
DDE02_03110	COG1272	protein, Hemolysin III
DDE02_03120	COG2153	protein acetylation
DDE02_03140	COG0183	Belongs to the thiolase family
DDE02_03145	COG2207	Transcriptional regulator
DDE02_03165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDE02_03185	COG0183	Belongs to the thiolase family
DDE02_03195	COG2885	chlorophyll binding
DDE02_03195	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DDE02_03200	COG1690	Belongs to the RtcB family
DDE02_03205	COG0833	amino acid
DDE02_03215	COG2233	PERMEase
DDE02_03220	COG1217	gtp-binding protein TYPA
DDE02_03245	COG2094	Belongs to the DNA glycosylase MPG family
DDE02_03250	COG4772	TonB-dependent receptor
DDE02_03255	COG1902	pentaerythritol trinitrate reductase activity
DDE02_03270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDE02_03275	COG0354	folic acid binding
DDE02_03295	COG2233	PERMEase
DDE02_03300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDE02_03305	COG0251	oxidation-reduction process
DDE02_03310	COG1335	isochorismatase
DDE02_03315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDE02_03325	COG0596	Alpha beta hydrolase
DDE02_03335	COG2824	Alkylphosphonate utilization operon protein PhnA
DDE02_03340	COG3422	double-strand break repair
DDE02_03380	COG0840	transmembrane signaling receptor activity
DDE02_03400	COG5510	response to toxic substance
DDE02_03410	COG2832	Protein of unknown function (DUF454)
DDE02_03415	COG1376	ErfK ybiS ycfS ynhG family protein
DDE02_03455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DDE02_03465	COG1289	transmembrane transporter activity
DDE02_03470	COG2814	Major facilitator Superfamily
DDE02_03495	COG1115	amino acid carrier protein
DDE02_03500	COG1752	Esterase of the alpha-beta hydrolase superfamily
DDE02_03505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDE02_03510	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DDE02_03515	COG3590	peptidase
DDE02_03540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDE02_03550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDE02_03555	COG1077	Cell shape determining protein MreB Mrl
DDE02_03560	COG1792	Involved in formation and maintenance of cell shape
DDE02_03565	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DDE02_03570	COG0424	maF-like protein
DDE02_03575	COG1530	ribonuclease E activity
DDE02_03585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDE02_03605	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDE02_03630	COG2207	Transcriptional regulator
DDE02_03710	COG0305	Participates in initiation and elongation during chromosome replication
DDE02_03745	COG0582	viral genome integration into host DNA
DDE02_03765	COG3046	protein related to deoxyribodipyrimidine photolyase
DDE02_03775	COG1113	amino acid transport
DDE02_03780	COG2828	Protein conserved in bacteria
DDE02_03785	COG0142	geranyltranstransferase activity
DDE02_03790	COG2315	Protein conserved in bacteria
DDE02_03805	COG1752	Esterase of the alpha-beta hydrolase superfamily
DDE02_03830	COG2194	sulfuric ester hydrolase activity
DDE02_03835	COG0745	RESPONSE REGULATOR receiver
DDE02_03840	COG0642	Histidine kinase
DDE02_03855	COG0004	ammonium transporteR
DDE02_03860	COG0583	DNA-binding transcription factor activity
DDE02_03880	COG0525	valine-tRNA ligase activity
DDE02_03890	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_03900	COG0393	Putative heavy-metal-binding
DDE02_03905	COG0393	Putative heavy-metal-binding
DDE02_03910	COG1538	Outer membrane efflux protein
DDE02_03920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_03925	COG0671	phosphoesterase, PA-phosphatase related
DDE02_03950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DDE02_03965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDE02_03965	COG1648	precorrin-2 dehydrogenase activity
DDE02_03970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DDE02_04005	COG0531	amino acid
DDE02_04020	COG0321	lipoyl(octanoyl) transferase activity
DDE02_04025	COG2921	Belongs to the UPF0250 family
DDE02_04070	COG2009	succinate dehydrogenase
DDE02_04075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DDE02_04080	COG1053	succinate dehydrogenase
DDE02_04085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDE02_04110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDE02_04130	COG2354	Protein conserved in bacteria
DDE02_04135	COG2321	neutral zinc metallopeptidase
DDE02_04165	COG2843	Capsule synthesis protein
DDE02_04185	COG0589	response to stress
DDE02_04195	COG0251	oxidation-reduction process
DDE02_04200	COG1309	transcriptional regulator
DDE02_04215	COG0505	Belongs to the CarA family
DDE02_04250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDE02_04255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DDE02_04300	COG2264	protein methyltransferase activity
DDE02_04310	COG0477	Major facilitator Superfamily
DDE02_04315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDE02_04330	COG1597	lipid kinase activity
DDE02_04335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DDE02_04365	COG0584	glycerophosphoryl diester phosphodiesterase
DDE02_04385	COG0741	lytic transglycosylase activity
DDE02_04410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDE02_04415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDE02_04460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_04470	COG0778	Nitroreductase
DDE02_04485	COG1929	Belongs to the glycerate kinase type-1 family
DDE02_04490	COG0243	molybdopterin cofactor binding
DDE02_04495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DDE02_04500	COG3339	Conserved Protein
DDE02_04510	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DDE02_04525	COG1115	amino acid carrier protein
DDE02_04530	COG1113	amino acid transport
DDE02_04540	COG0019	diaminopimelate decarboxylase activity
DDE02_04550	COG1280	lysine exporter protein (LysE YggA)
DDE02_04555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DDE02_04585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_04615	COG4591	ABC-type transport system involved in lipoprotein release permease component
DDE02_04620	COG1136	(ABC) transporter
DDE02_04625	COG2333	competence protein COMEC
DDE02_04625	COG0658	competence protein
DDE02_04635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DDE02_04635	COG0616	signal peptide processing
DDE02_04640	COG0596	Alpha beta hydrolase
DDE02_04645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDE02_04655	COG0628	permease
DDE02_04695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDE02_04715	COG0823	Involved in the tonB-independent uptake of proteins
DDE02_04735	COG0824	Thioesterase
DDE02_04740	COG1473	amidohydrolase
DDE02_04760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDE02_04760	COG0047	phosphoribosylformylglycinamidine synthase activity
DDE02_04765	COG2814	Major facilitator Superfamily
DDE02_04770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDE02_04775	COG1024	Enoyl-CoA hydratase
DDE02_04780	COG1051	belongs to the nudix hydrolase family
DDE02_04780	COG1056	cytidyltransferase-related domain
DDE02_04795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DDE02_04810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DDE02_04825	COG4625	pathogenesis
DDE02_04830	COG0583	DNA-binding transcription factor activity
DDE02_04835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DDE02_04840	COG4208	sulfate ABC transporter
DDE02_04845	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DDE02_04855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DDE02_04860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDE02_04865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDE02_04885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDE02_04895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDE02_04900	COG0481	GTPase activity
DDE02_04905	COG0681	Belongs to the peptidase S26 family
DDE02_04915	COG0571	ribonuclease III activity
DDE02_04920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDE02_04930	COG1381	Involved in DNA repair and RecF pathway recombination
DDE02_04935	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DDE02_04945	COG4221	oxidoreductase activity
DDE02_04975	COG0436	Aminotransferase
DDE02_04995	COG0556	nucleotide-excision repair
DDE02_05005	COG2962	Rard protein
DDE02_05050	COG2070	2-Nitropropane dioxygenase
DDE02_05065	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DDE02_05080	COG1215	transferase activity, transferring glycosyl groups
DDE02_05095	COG0415	Belongs to the DNA photolyase family
DDE02_05105	COG1252	NADH dehydrogenase
DDE02_05110	COG1686	Belongs to the peptidase S11 family
DDE02_05125	COG1187	pseudouridine synthase activity
DDE02_05140	COG0477	Major facilitator Superfamily
DDE02_05145	COG0583	DNA-binding transcription factor activity
DDE02_05150	COG1823	symporter activity
DDE02_05160	COG0612	Peptidase, M16
DDE02_05185	COG0352	thiamine-phosphate diphosphorylase activity
DDE02_05220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDE02_05235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDE02_05240	COG0076	glutamate decarboxylase activity
DDE02_05250	COG1522	sequence-specific DNA binding
DDE02_05255	COG3961	Belongs to the TPP enzyme family
DDE02_05260	COG1113	amino acid transport
DDE02_05265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DDE02_05270	COG0573	inorganic phosphate transmembrane transporter activity
DDE02_05280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDE02_05285	COG0616	signal peptide processing
DDE02_05325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DDE02_05330	COG1686	Belongs to the peptidase S11 family
DDE02_05355	COG0583	DNA-binding transcription factor activity
DDE02_05360	COG1067	ATP-dependent peptidase activity
DDE02_05365	COG2211	Major facilitator Superfamily
DDE02_05400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDE02_05405	COG1966	Carbon starvation protein
DDE02_05410	COG2879	small protein
DDE02_05420	COG0582	viral genome integration into host DNA
DDE02_05500	COG1741	Belongs to the pirin family
DDE02_05515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDE02_05520	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE02_05525	COG4605	iron ion homeostasis
DDE02_05530	COG4604	ABC transporter, ATP-binding protein
DDE02_05535	COG4607	ABC-type enterochelin transport system periplasmic component
DDE02_05540	COG4774	siderophore transport
DDE02_05550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDE02_05555	COG1021	2,3-dihydroxybenzoate-AMP ligase
DDE02_05560	COG1535	isochorismatase
DDE02_05560	COG3433	isochorismatase activity
DDE02_05575	COG1132	(ABC) transporter
DDE02_05580	COG1132	(ABC) transporter
DDE02_05585	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DDE02_05590	COG2977	Belongs to the P-Pant transferase superfamily
DDE02_05595	COG1169	isochorismate synthase
DDE02_05615	COG3739	integral membrane protein
DDE02_05635	COG0302	gtp cyclohydrolase
DDE02_05645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDE02_05655	COG2840	Smr protein MutS2
DDE02_05670	COG4771	TonB-dependent receptor
DDE02_05675	COG0308	aminopeptidase N
DDE02_05680	COG0512	Glutamine amidotransferase of anthranilate synthase
DDE02_05730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDE02_05735	COG4197	protein conserved in bacteria, prophage-related
DDE02_05825	COG5410	chromosome segregation
DDE02_05830	COG3567	Phage-associated protein, HI1409 family
DDE02_05850	COG3566	protein conserved in bacteria
DDE02_05945	COG3179	chitinase
DDE02_05970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDE02_05990	COG0582	viral genome integration into host DNA
DDE02_06005	COG0174	glutamine synthetase
DDE02_06015	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DDE02_06050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DDE02_06055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDE02_06060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDE02_06080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDE02_06085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DDE02_06090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DDE02_06105	COG1960	acyl-CoA dehydrogenase activity
DDE02_06110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DDE02_06115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDE02_06125	COG2223	nitrite transmembrane transporter activity
DDE02_06135	COG0024	Methionine aminopeptidase
DDE02_06140	COG0052	Belongs to the universal ribosomal protein uS2 family
DDE02_06155	COG2207	Transcriptional regulator
DDE02_06180	COG2951	lytic endotransglycosylase activity
DDE02_06185	COG0772	Belongs to the SEDS family
DDE02_06200	COG0842	Transport permease protein
DDE02_06205	COG1131	(ABC) transporter
DDE02_06250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_06260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDE02_06265	COG4215	(ABC) transporter
DDE02_06270	COG4160	amino acid transport
DDE02_06275	COG4598	ABC transporter
DDE02_06285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDE02_06290	COG0826	peptidase U32
DDE02_06295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_06300	COG0384	phenazine biosynthesis protein PhzF
DDE02_06310	COG1720	tRNA m6t6A37 methyltransferase activity
DDE02_06320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDE02_06335	COG0642	Histidine kinase
DDE02_06345	COG0494	nUDIX hydrolase
DDE02_06355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDE02_06360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDE02_06365	COG3139	Protein of unknown function (DUF1315)
DDE02_06380	COG1301	dicarboxylic acid transport
DDE02_06385	COG1960	acyl-CoA dehydrogenase activity
DDE02_06400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDE02_06410	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDE02_06430	COG1690	Belongs to the RtcB family
DDE02_06435	COG1234	tRNA 3'-trailer cleavage
DDE02_06440	COG4650	regulator
DDE02_06470	COG2363	Small membrane protein
DDE02_06490	COG0513	Belongs to the DEAD box helicase family
DDE02_06500	COG0778	Nitroreductase
DDE02_06530	COG1286	toxin biosynthetic process
DDE02_06555	COG4783	chaperone-mediated protein folding
DDE02_06560	COG1610	YqeY-like protein
DDE02_06615	COG1278	Cold shock
DDE02_06630	COG3243	poly(R)-hydroxyalkanoic acid synthase
DDE02_06635	COG0786	glutamate:sodium symporter activity
DDE02_06640	COG0475	glutathione-regulated potassium exporter activity
DDE02_06640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDE02_06655	COG1309	transcriptional regulator
DDE02_06665	COG2985	domain, Protein
DDE02_06675	COG2995	paraquat-inducible protein a
DDE02_06680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DDE02_06680	COG3008	intermembrane lipid transfer
DDE02_06690	COG2351	hydroxyisourate hydrolase activity
DDE02_06730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDE02_06740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDE02_06745	COG0642	Histidine kinase
DDE02_06750	COG0745	RESPONSE REGULATOR receiver
DDE02_06765	COG1794	racemase activity, acting on amino acids and derivatives
DDE02_06795	COG1301	dicarboxylic acid transport
DDE02_06805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDE02_06810	COG2011	ABC-type metal ion transport system permease component
DDE02_06815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDE02_06825	COG0151	Belongs to the GarS family
DDE02_06835	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DDE02_06865	COG2308	Evidence 4 Homologs of previously reported genes of
DDE02_06875	COG1305	Transglutaminase-like
DDE02_06885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DDE02_06890	COG0305	Participates in initiation and elongation during chromosome replication
DDE02_06915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DDE02_06920	COG1845	cytochrome c oxidase, subunit III
DDE02_06925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DDE02_06955	COG1649	PFAM Uncharacterised BCR, COG1649
DDE02_06955	COG0726	polysaccharide deacetylase
DDE02_06960	COG1215	transferase activity, transferring glycosyl groups
DDE02_06965	COG3658	cytochrome
DDE02_06975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDE02_06990	COG0583	DNA-binding transcription factor activity
DDE02_07005	COG2890	protein-(glutamine-N5) methyltransferase activity
DDE02_07010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDE02_07015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDE02_07030	COG1960	acyl-CoA dehydrogenase activity
DDE02_07035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDE02_07050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DDE02_07060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DDE02_07065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DDE02_07070	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DDE02_07075	COG2205	protein histidine kinase activity
DDE02_07080	COG0745	RESPONSE REGULATOR receiver
DDE02_07085	COG0174	glutamine synthetase
DDE02_07100	COG0477	Major facilitator Superfamily
DDE02_07105	COG0729	surface antigen
DDE02_07140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDE02_07145	COG2814	Major facilitator Superfamily
DDE02_07190	COG0776	regulation of translation
DDE02_07215	COG3409	Peptidoglycan-binding domain 1 protein
DDE02_07215	COG3267	Type II secretory pathway component ExeA
DDE02_07240	COG0681	Belongs to the peptidase S26 family
DDE02_07275	COG4373	Mu-like prophage FluMu protein gp28
DDE02_07295	COG2369	cell adhesion
DDE02_07400	COG0583	DNA-binding transcription factor activity
DDE02_07415	COG1187	pseudouridine synthase activity
DDE02_07435	COG0802	atpase or kinase
DDE02_07440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DDE02_07450	COG1923	regulation of RNA biosynthetic process
DDE02_07455	COG0697	spore germination
DDE02_07470	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDE02_07480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDE02_07485	COG0519	Catalyzes the synthesis of GMP from XMP
DDE02_07485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDE02_07490	COG4302	ethanolamine ammonia-lyase activity
DDE02_07495	COG4303	Ethanolamine ammonia lyase large subunit
DDE02_07500	COG0531	amino acid
DDE02_07520	COG1454	alcohol dehydrogenase
DDE02_07525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDE02_07550	COG0308	aminopeptidase N
DDE02_07590	COG1605	Chorismate mutase
DDE02_07615	COG4772	TonB-dependent receptor
DDE02_07620	COG4774	siderophore transport
DDE02_07675	COG3772	lysozyme
DDE02_07700	COG0583	DNA-binding transcription factor activity
DDE02_07735	COG0488	(ABC) transporter
DDE02_07740	COG0589	response to stress
DDE02_07770	COG3135	benzoate transporter
DDE02_07775	COG1522	sequence-specific DNA binding
DDE02_07785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDE02_07790	COG0583	DNA-binding transcription factor activity
DDE02_07800	COG0183	Belongs to the thiolase family
DDE02_07805	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_07810	COG2030	dehydratase
DDE02_07815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDE02_07840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDE02_07850	COG0824	Thioesterase
DDE02_07855	COG1454	alcohol dehydrogenase
DDE02_07870	COG1335	isochorismatase
DDE02_07890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDE02_07945	COG2814	Major facilitator Superfamily
DDE02_07960	COG0511	ligase activity, forming carbon-carbon bonds
DDE02_07985	COG4264	IucA IucC family
DDE02_07995	COG4264	IucA IucC family
DDE02_08000	COG2423	ornithine cyclodeaminase activity
DDE02_08005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDE02_08010	COG1116	anion transmembrane transporter activity
DDE02_08010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDE02_08025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDE02_08025	COG2146	nitrite reductase [NAD(P)H] activity
DDE02_08030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDE02_08035	COG0243	molybdopterin cofactor binding
DDE02_08045	COG0243	molybdopterin cofactor binding
DDE02_08050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DDE02_08065	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDE02_08065	COG0315	cyclic pyranopterin monophosphate synthase activity
DDE02_08070	COG0303	'Molybdopterin
DDE02_08080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_08085	COG0697	spore germination
DDE02_08110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDE02_08180	COG2204	response regulator
DDE02_08185	COG3852	Histidine kinase
DDE02_08210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDE02_08215	COG0575	Belongs to the CDS family
DDE02_08250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDE02_08265	COG2137	regulation of response to DNA damage stimulus
DDE02_08275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DDE02_08280	COG1011	Hydrolase
DDE02_08295	COG1522	sequence-specific DNA binding
DDE02_08305	COG1113	amino acid transport
DDE02_08325	COG0659	secondary active sulfate transmembrane transporter activity
DDE02_08360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDE02_08360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDE02_08360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DDE02_08365	COG1105	Belongs to the carbohydrate kinase PfkB family
DDE02_08370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDE02_08370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDE02_08390	COG3193	protein, possibly involved in utilization of glycolate and propanediol
DDE02_08400	COG0024	Methionine aminopeptidase
DDE02_08405	COG0583	DNA-binding transcription factor activity
DDE02_08415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DDE02_08420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDE02_08425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DDE02_08425	COG0517	IMP dehydrogenase activity
DDE02_08450	COG0552	protein localization to endoplasmic reticulum
DDE02_08475	COG4890	Cyd operon protein YbgT
DDE02_08480	COG1294	oxidase, subunit
DDE02_08495	COG1585	Membrane protein implicated in regulation of membrane protease activity
DDE02_08505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDE02_08520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDE02_08525	COG0569	domain protein
DDE02_08530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDE02_08560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DDE02_08565	COG0542	response to heat
DDE02_08590	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDE02_08590	COG1902	pentaerythritol trinitrate reductase activity
DDE02_08630	COG0148	phosphopyruvate hydratase activity
DDE02_08635	COG2323	membrane
DDE02_08645	COG4773	Receptor
DDE02_08650	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DDE02_08660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DDE02_08665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DDE02_08670	COG0183	Belongs to the thiolase family
DDE02_08675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDE02_08680	COG0596	Alpha beta hydrolase
DDE02_08685	COG2271	Major facilitator Superfamily
DDE02_08690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDE02_08695	COG3485	protocatechuate 3,4-dioxygenase
DDE02_08700	COG3485	protocatechuate 3,4-dioxygenase
DDE02_08705	COG0710	3-dehydroquinate dehydratase activity
DDE02_08710	COG3420	alginic acid biosynthetic process
DDE02_08715	COG3659	wide pore channel activity
DDE02_08720	COG4993	Dehydrogenase
DDE02_08730	COG2391	methyltransferase activity
DDE02_08745	COG1414	Transcriptional regulator
DDE02_08750	COG0583	DNA-binding transcription factor activity
DDE02_08755	COG1960	acyl-CoA dehydrogenase activity
DDE02_08780	COG2814	Major facilitator Superfamily
DDE02_08790	COG0154	amidase activity
DDE02_08810	COG4638	Rieske (2fe-2S)
DDE02_08820	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_08830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDE02_08840	COG3733	amine oxidase
DDE02_08850	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_08855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDE02_08860	COG0183	Belongs to the thiolase family
DDE02_08865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DDE02_08870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DDE02_08880	COG4829	muconolactone delta-isomerase
DDE02_08885	COG4948	Mandelate Racemase Muconate Lactonizing
DDE02_08890	COG0583	DNA-binding transcription factor activity
DDE02_08900	COG2186	Transcriptional regulator
DDE02_08920	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_08925	COG2351	hydroxyisourate hydrolase activity
DDE02_08930	COG2233	PERMEase
DDE02_08940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_08945	COG2186	Transcriptional regulator
DDE02_08960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDE02_08970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDE02_08990	COG1902	pentaerythritol trinitrate reductase activity
DDE02_08990	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDE02_09030	COG1309	transcriptional regulator
DDE02_09035	COG0583	DNA-binding transcription factor activity
DDE02_09040	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_09045	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_09050	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_09060	COG1960	acyl-CoA dehydrogenase activity
DDE02_09070	COG0318	PFAM AMP-dependent synthetase and ligase
DDE02_09180	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DDE02_09235	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DDE02_09245	COG4628	conserved protein (DUF2132)
DDE02_09325	COG3539	Fimbrial protein
DDE02_09350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DDE02_09360	COG0753	catalase activity
DDE02_09380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDE02_09390	COG2205	protein histidine kinase activity
DDE02_09395	COG0745	RESPONSE REGULATOR receiver
DDE02_09400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_09405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DDE02_09460	COG1535	isochorismatase
DDE02_09460	COG3433	isochorismatase activity
DDE02_09465	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_09470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DDE02_09475	COG4149	molybdate abc transporter
DDE02_09480	COG0725	ABC transporter, periplasmic molybdate-binding protein
DDE02_09490	COG4638	Rieske (2fe-2S)
DDE02_09495	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DDE02_09500	COG0543	2 iron, 2 sulfur cluster binding
DDE02_09500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDE02_09515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDE02_09525	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_09545	COG2207	Transcriptional regulator
DDE02_09550	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_09555	COG2610	gluconate transmembrane transporter activity
DDE02_09595	COG0583	DNA-binding transcription factor activity
DDE02_09610	COG2031	fatty acid transporter
DDE02_09615	COG0183	Belongs to the thiolase family
DDE02_09620	COG0583	DNA-binding transcription factor activity
DDE02_09625	COG0583	DNA-binding transcription factor activity
DDE02_09640	COG1027	Aspartate ammonia-lyase
DDE02_09650	COG0477	Major facilitator Superfamily
DDE02_09660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDE02_09665	COG1733	regulation of RNA biosynthetic process
DDE02_09670	COG3708	Transcriptional regulator
DDE02_09670	COG2207	Transcriptional regulator
DDE02_09690	COG0730	response to heat
DDE02_09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDE02_09700	COG3453	Protein conserved in bacteria
DDE02_09710	COG3781	membrane
DDE02_09715	COG1063	alcohol dehydrogenase
DDE02_09725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDE02_09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDE02_09735	COG0022	dehydrogenase e1 component
DDE02_09740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDE02_09745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DDE02_09760	COG3706	GGDEF domain
DDE02_09795	COG0133	tryptophan synthase activity
DDE02_09805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDE02_09835	COG0583	DNA-binding transcription factor activity
DDE02_09840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDE02_09855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDE02_09915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DDE02_09920	COG4773	Receptor
DDE02_09945	COG0730	response to heat
DDE02_09950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DDE02_09970	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DDE02_10000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDE02_10015	COG1960	acyl-CoA dehydrogenase activity
DDE02_10020	COG1960	acyl-CoA dehydrogenase activity
DDE02_10025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DDE02_10030	COG2207	Transcriptional regulator
DDE02_10035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDE02_10040	COG0776	regulation of translation
DDE02_10065	COG0822	iron-sulfur transferase activity
DDE02_10070	COG0316	Belongs to the HesB IscA family
DDE02_10100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DDE02_10120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DDE02_10125	COG0702	epimerase
DDE02_10165	COG0601	transmembrane transport
DDE02_10170	COG0339	signal peptide processing
DDE02_10175	COG4166	transmembrane transport
DDE02_10220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DDE02_10225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DDE02_10240	COG2431	L-lysine efflux transmembrane transporter activity
DDE02_10255	COG0776	regulation of translation
DDE02_10320	COG0084	hydrolase, TatD family'
DDE02_10340	COG1663	tetraacyldisaccharide 4'-kinase activity
DDE02_10345	COG1132	(ABC) transporter
DDE02_10355	COG0811	peptide transport
DDE02_10360	COG1475	DNA binding
DDE02_10365	COG1192	Involved in chromosome partitioning
DDE02_10375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DDE02_10380	COG3178	'Phosphotransferase
DDE02_10390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDE02_10415	COG0424	maF-like protein
DDE02_10420	COG2850	peptidyl-arginine hydroxylation
DDE02_10430	COG0640	Transcriptional regulator
DDE02_10440	COG3619	membrane
DDE02_10445	COG3122	Protein conserved in bacteria
DDE02_10450	COG1132	(ABC) transporter
DDE02_10470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DDE02_10475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDE02_10485	COG0506	proline dehydrogenase activity
DDE02_10485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DDE02_10485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DDE02_10490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DDE02_10505	COG3698	Phosphodiester glycosidase
DDE02_10515	COG2353	YceI-like domain
DDE02_10525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DDE02_10570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DDE02_10570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DDE02_10595	COG3539	Fimbrial protein
DDE02_10630	COG0583	DNA-binding transcription factor activity
DDE02_10635	COG0697	spore germination
DDE02_10645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DDE02_10655	COG0583	DNA-binding transcription factor activity
DDE02_10670	COG1309	transcriptional regulator
DDE02_10685	COG1522	sequence-specific DNA binding
DDE02_10695	COG1126	abc transporter atp-binding protein
DDE02_10700	COG0765	amino acid transport
DDE02_10705	COG0765	amino acid transport
DDE02_10735	COG1464	Belongs to the NlpA lipoprotein family
DDE02_10745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDE02_10750	COG2011	ABC-type metal ion transport system permease component
DDE02_10755	COG0012	GTP binding
DDE02_10780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DDE02_10820	COG0386	Belongs to the glutathione peroxidase family
DDE02_10830	COG0436	Aminotransferase
DDE02_10835	COG1301	dicarboxylic acid transport
DDE02_10870	COG3634	alkyl hydroperoxide reductase activity
DDE02_10885	COG0583	DNA-binding transcription factor activity
DDE02_10890	COG0431	NADPH-dependent FMN reductase
DDE02_10895	COG0798	PFAM Bile acid sodium symporter
DDE02_10905	COG0640	Transcriptional regulator
DDE02_10920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DDE02_10930	COG0583	DNA-binding transcription factor activity
DDE02_10940	COG1953	Uracil, thiamine, allantoin
DDE02_10950	COG2175	clavaminate synthase activity
DDE02_10955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDE02_10960	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DDE02_10965	COG4521	taurine ABC transporter
DDE02_10975	COG0477	Major facilitator Superfamily
DDE02_11000	COG1271	oxidase subunit
DDE02_11005	COG1294	oxidase, subunit
DDE02_11015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_11035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDE02_11055	COG3052	prosthetic group binding
DDE02_11060	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DDE02_11085	COG1346	cytolysis
DDE02_11095	COG0583	DNA-binding transcription factor activity
DDE02_11100	COG0625	glutathione transferase activity
DDE02_11105	COG0625	glutathione transferase activity
DDE02_11125	COG0583	DNA-binding transcription factor activity
DDE02_11130	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_11140	COG1045	serine acetyltransferase
DDE02_11145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDE02_11150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDE02_11160	COG1280	lysine exporter protein (LysE YggA)
DDE02_11170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDE02_11175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDE02_11185	COG0765	amino acid transport
DDE02_11190	COG0765	amino acid transport
DDE02_11210	COG0784	Response regulator, receiver
DDE02_11210	COG2205	protein histidine kinase activity
DDE02_11230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDE02_11250	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_11385	COG2369	cell adhesion
DDE02_11390	COG4383	Mu-like prophage protein gp29
DDE02_11395	COG4373	Mu-like prophage FluMu protein gp28
DDE02_11485	COG0776	regulation of translation
DDE02_11545	COG0583	DNA-binding transcription factor activity
DDE02_11560	COG2814	Major facilitator Superfamily
DDE02_11575	COG0318	PFAM AMP-dependent synthetase and ligase
DDE02_11580	COG1309	transcriptional regulator
DDE02_11585	COG1960	acyl-CoA dehydrogenase activity
DDE02_11590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDE02_11595	COG1024	Enoyl-CoA hydratase
DDE02_11600	COG4770	biotin carboxylase activity
DDE02_11610	COG0583	DNA-binding transcription factor activity
DDE02_11625	COG1960	acyl-CoA dehydrogenase activity
DDE02_11635	COG2814	Major facilitator Superfamily
DDE02_11645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DDE02_11650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DDE02_11655	COG2814	Major facilitator Superfamily
DDE02_11660	COG1960	acyl-CoA dehydrogenase activity
DDE02_11665	COG1024	Enoyl-CoA hydratase
DDE02_11670	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_11675	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDE02_11680	COG0183	Belongs to the thiolase family
DDE02_11690	COG2814	Major facilitator Superfamily
DDE02_11700	COG1024	Enoyl-CoA hydratase
DDE02_11715	COG1960	acyl-CoA dehydrogenase activity
DDE02_11720	COG2814	Major facilitator Superfamily
DDE02_11725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDE02_11730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DDE02_11745	COG3842	ATPase activity
DDE02_11750	COG1840	ABC-type Fe3 transport system, periplasmic component
DDE02_11770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_11775	COG1414	Transcriptional regulator
DDE02_11785	COG0583	DNA-binding transcription factor activity
DDE02_11820	COG2050	protein possibly involved in aromatic compounds catabolism
DDE02_11830	COG3327	negative regulation of DNA-templated transcription, initiation
DDE02_11835	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DDE02_11840	COG0183	Belongs to the thiolase family
DDE02_11845	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDE02_11850	COG1024	Enoyl-CoA hydratase
DDE02_11855	COG1024	Enoyl-CoA hydratase
DDE02_11860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDE02_11865	COG2151	metal-sulfur cluster biosynthetic enzyme
DDE02_11870	COG3396	Phenylacetate-CoA oxygenase
DDE02_11875	COG3460	Phenylacetate-CoA oxygenase
DDE02_11880	COG3396	Phenylacetate-CoA oxygenase
DDE02_11885	COG2030	dehydratase
DDE02_11885	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_11890	COG1760	l-serine dehydratase
DDE02_11910	COG0789	Transcriptional regulator
DDE02_11920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDE02_11925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_11940	COG2807	transmembrane transport
DDE02_11945	COG0590	tRNA wobble adenosine to inosine editing
DDE02_11950	COG0666	response to abiotic stimulus
DDE02_11985	COG0477	Major facilitator Superfamily
DDE02_12000	COG1116	anion transmembrane transporter activity
DDE02_12005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDE02_12015	COG0864	Transcriptional regulator
DDE02_12025	COG1733	regulation of RNA biosynthetic process
DDE02_12030	COG2249	NAD(P)H dehydrogenase (quinone) activity
DDE02_12035	COG0439	Biotin carboxylase
DDE02_12050	COG1063	alcohol dehydrogenase
DDE02_12055	COG1250	3-hydroxyacyl-CoA dehydrogenase
DDE02_12090	COG3210	domain, Protein
DDE02_12095	COG2831	hemolysin activation secretion protein
DDE02_12100	COG0038	chloride channel
DDE02_12105	COG4770	biotin carboxylase activity
DDE02_12125	COG1914	H( )-stimulated, divalent metal cation uptake system
DDE02_12140	COG1595	DNA-templated transcription, initiation
DDE02_12150	COG3220	belongs to the UPF0276 family
DDE02_12260	COG3038	cytochrome b561
DDE02_12265	COG0753	catalase activity
DDE02_12270	COG1733	regulation of RNA biosynthetic process
DDE02_12290	COG1469	GTP cyclohydrolase I activity
DDE02_12295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DDE02_12295	COG4451	ribulose bisphosphate carboxylase, small
DDE02_12300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDE02_12315	COG1522	sequence-specific DNA binding
DDE02_12320	COG0531	amino acid
DDE02_12325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DDE02_12340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DDE02_12355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DDE02_12365	COG4122	O-methyltransferase activity
DDE02_12395	COG1538	Outer membrane efflux protein
DDE02_12400	COG1137	ATPase activity
DDE02_12405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DDE02_12415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DDE02_12470	COG2814	Major facilitator Superfamily
DDE02_12480	COG0668	transmembrane transport
DDE02_12525	COG1309	transcriptional regulator
DDE02_12555	COG2226	methyltransferase
DDE02_12560	COG1011	Hydrolase
DDE02_12585	COG1278	Cold shock
DDE02_12590	COG1560	Kdo2-lipid A biosynthetic process
DDE02_12640	COG1570	exodeoxyribonuclease VII activity
DDE02_12725	COG2871	sodium ion transport
DDE02_12735	COG0583	DNA-binding transcription factor activity
DDE02_12745	COG4638	Rieske (2fe-2S)
DDE02_12750	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DDE02_12755	COG0543	2 iron, 2 sulfur cluster binding
DDE02_12755	COG0633	Ferredoxin
DDE02_12760	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_12765	COG3135	benzoate transporter
DDE02_12770	COG2814	Major facilitator Superfamily
DDE02_12785	COG1643	Atp-dependent helicase
DDE02_12810	COG3634	alkyl hydroperoxide reductase activity
DDE02_12830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDE02_12860	COG0625	glutathione transferase activity
DDE02_12870	COG2885	chlorophyll binding
DDE02_12905	COG0542	response to heat
DDE02_12920	COG1765	OsmC-like protein
DDE02_12935	COG0667	Aldo Keto reductase
DDE02_12950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DDE02_12965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDE02_12980	COG2194	sulfuric ester hydrolase activity
DDE02_13030	COG2314	TM2 domain
DDE02_13090	COG3566	protein conserved in bacteria
DDE02_13110	COG3567	Phage-associated protein, HI1409 family
DDE02_13115	COG5410	chromosome segregation
DDE02_13255	COG0527	aspartate kinase activity
DDE02_13265	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDE02_13275	COG3038	cytochrome b561
DDE02_13280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDE02_13285	COG2252	PERMEase
DDE02_13295	COG1741	Belongs to the pirin family
DDE02_13300	COG1309	transcriptional regulator
DDE02_13315	COG2072	flavoprotein involved in K transport
DDE02_13320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DDE02_13350	COG1944	ATP diphosphatase activity
DDE02_13370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DDE02_13385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DDE02_13405	COG2814	Major facilitator Superfamily
DDE02_13410	COG1024	Enoyl-CoA hydratase
DDE02_13415	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_13425	COG1960	acyl-CoA dehydrogenase activity
DDE02_13450	COG2186	Transcriptional regulator
DDE02_13455	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_13465	COG4948	Mandelate Racemase Muconate Lactonizing
DDE02_13470	COG2271	Major facilitator Superfamily
DDE02_13475	COG2721	sulfolactate sulfo-lyase activity
DDE02_13480	COG0697	spore germination
DDE02_13500	COG3210	domain, Protein
DDE02_13505	COG2831	hemolysin activation secretion protein
DDE02_13510	COG1113	amino acid transport
DDE02_13530	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_13550	COG0531	amino acid
DDE02_13560	COG1113	amino acid transport
DDE02_13605	COG4269	membrane
DDE02_13640	COG2059	Chromate
DDE02_13650	COG1230	cation diffusion facilitator family transporter
DDE02_13665	COG2814	Major facilitator Superfamily
DDE02_13770	COG0582	viral genome integration into host DNA
DDE02_13780	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDE02_13780	COG1902	pentaerythritol trinitrate reductase activity
DDE02_13790	COG3706	GGDEF domain
DDE02_13790	COG2203	Gaf domain
DDE02_13790	COG4251	negative regulation of phosphorylation
DDE02_13790	COG5001	Diguanylate cyclase
DDE02_13800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDE02_13825	COG4172	Belongs to the ABC transporter superfamily
DDE02_13830	COG4239	(ABC) transporter, permease
DDE02_13835	COG4174	ABC transporter (Permease)
DDE02_13840	COG4166	transmembrane transport
DDE02_13845	COG0741	lytic transglycosylase activity
DDE02_13845	COG1388	LysM domain
DDE02_13845	COG0741	lytic transglycosylase activity
DDE02_13845	COG1388	LysM domain
DDE02_13890	COG0583	DNA-binding transcription factor activity
DDE02_13895	COG1279	arginine transmembrane transporter activity
DDE02_13905	COG0789	Transcriptional regulator
DDE02_13915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_13920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_13925	COG0006	proline dipeptidase activity
DDE02_13965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDE02_13980	COG3384	dioxygenase
DDE02_13990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDE02_13995	COG2878	Part of a membrane complex involved in electron transport
DDE02_14000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DDE02_14025	COG0768	penicillin binding
DDE02_14030	COG0742	ribosomal rna small subunit methyltransferase
DDE02_14045	COG0830	nickel cation binding
DDE02_14055	COG0804	urea catabolic process
DDE02_14080	COG3015	lipoprotein NlpE involved in copper resistance
DDE02_14095	COG1253	flavin adenine dinucleotide binding
DDE02_14100	COG2851	Citrate transporter
DDE02_14150	COG1773	rubredoxin
DDE02_14155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DDE02_14160	COG2267	carboxylic ester hydrolase activity
DDE02_14165	COG0583	DNA-binding transcription factor activity
DDE02_14195	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DDE02_14200	COG4181	ATPase activity
DDE02_14245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DDE02_14265	COG0306	phosphate transporter
DDE02_14280	COG3958	Transketolase
DDE02_14285	COG3959	Transketolase, thiamine diphosphate binding domain
DDE02_14290	COG2271	Major facilitator Superfamily
DDE02_14295	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_14300	COG0583	DNA-binding transcription factor activity
DDE02_14320	COG2223	nitrite transmembrane transporter activity
DDE02_14325	COG0662	Cupin 2, conserved barrel domain protein
DDE02_14325	COG2207	Transcriptional regulator
DDE02_14330	COG2066	Belongs to the glutaminase family
DDE02_14335	COG0242	peptide deformylase activity
DDE02_14340	COG0477	Major facilitator Superfamily
DDE02_14350	COG0028	Belongs to the TPP enzyme family
DDE02_14365	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_14370	COG2267	carboxylic ester hydrolase activity
DDE02_14380	COG2271	Major facilitator Superfamily
DDE02_14385	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDE02_14395	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_14415	COG1414	Transcriptional regulator
DDE02_14430	COG1024	Enoyl-CoA hydratase
DDE02_14440	COG1215	transferase activity, transferring glycosyl groups
DDE02_14445	COG0726	polysaccharide deacetylase
DDE02_14445	COG1649	PFAM Uncharacterised BCR, COG1649
DDE02_14455	COG4681	YaeQ
DDE02_14465	COG0523	cobalamin synthesis protein
DDE02_14475	COG1607	acyl-coa hydrolase
DDE02_14485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDE02_14490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDE02_14495	COG1309	transcriptional regulator
DDE02_14520	COG2040	homocysteine
DDE02_14525	COG0531	amino acid
DDE02_14575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDE02_14580	COG0477	Major facilitator Superfamily
DDE02_14650	COG1401	restriction endodeoxyribonuclease activity
DDE02_14665	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DDE02_14690	COG0629	single-stranded DNA binding
DDE02_14735	COG0582	viral genome integration into host DNA
DDE02_14745	COG0405	Gamma-glutamyltransferase
DDE02_14750	COG2814	Major facilitator Superfamily
DDE02_14760	COG2050	protein possibly involved in aromatic compounds catabolism
DDE02_14775	COG1090	epimerase
DDE02_14795	COG0420	3'-5' exonuclease activity
DDE02_14820	COG0735	belongs to the Fur family
DDE02_14825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDE02_14830	COG2914	Belongs to the UPF0125 (RnfH) family
DDE02_14850	COG0121	glutamine amidotransferase
DDE02_14865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDE02_14875	COG0210	DNA helicase
DDE02_14880	COG2885	chlorophyll binding
DDE02_14885	COG0204	Acyl-transferase
DDE02_14900	COG2894	cell division
DDE02_14915	COG1280	lysine exporter protein (LysE YggA)
DDE02_14920	COG1674	ftsk spoiiie
DDE02_14925	COG0492	ferredoxin-NADP+ reductase activity
DDE02_14930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DDE02_14940	COG0456	acetyltransferase
DDE02_14955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDE02_14960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDE02_14970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDE02_14985	COG1981	membrane
DDE02_14995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDE02_14995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDE02_15015	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_15020	COG4638	Rieske (2fe-2S)
DDE02_15025	COG0657	acetylesterase activity
DDE02_15035	COG0473	3-isopropylmalate dehydrogenase activity
DDE02_15040	COG0583	DNA-binding transcription factor activity
DDE02_15060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDE02_15095	COG0358	DNA primase activity
DDE02_15110	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DDE02_15140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DDE02_15170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDE02_15180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DDE02_15180	COG0352	thiamine-phosphate diphosphorylase activity
DDE02_15180	COG0351	phosphomethylpyrimidine kinase
DDE02_15185	COG1652	LysM domain
DDE02_15210	COG1399	metal-binding, possibly nucleic acid-binding protein
DDE02_15215	COG3101	peptidyl-lysine hydroxylation
DDE02_15220	COG0009	L-threonylcarbamoyladenylate synthase
DDE02_15225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DDE02_15230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DDE02_15245	COG4106	trans-aconitate 2-methyltransferase activity
DDE02_15260	COG0596	Alpha beta hydrolase
DDE02_15260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDE02_15260	COG2226	methyltransferase
DDE02_15270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DDE02_15275	COG2223	nitrite transmembrane transporter activity
DDE02_15295	COG1196	nuclear chromosome segregation
DDE02_15305	COG0730	response to heat
DDE02_15320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DDE02_15330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDE02_15385	COG0489	protein tyrosine kinase activity
DDE02_15395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDE02_15395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDE02_15430	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DDE02_15435	COG2081	HI0933 family
DDE02_15445	COG0668	transmembrane transport
DDE02_15465	COG0583	DNA-binding transcription factor activity
DDE02_15485	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDE02_15490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDE02_15520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DDE02_15545	COG2199	diguanylate cyclase activity
DDE02_15560	COG0745	RESPONSE REGULATOR receiver
DDE02_15575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDE02_15615	COG0110	maltose O-acetyltransferase activity
DDE02_15620	COG0438	transferase activity, transferring glycosyl groups
DDE02_15690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DDE02_15705	COG0583	DNA-binding transcription factor activity
DDE02_15740	COG0583	DNA-binding transcription factor activity
DDE02_15775	COG0583	DNA-binding transcription factor activity
DDE02_15780	COG1053	succinate dehydrogenase
DDE02_15795	COG1309	transcriptional regulator
DDE02_15805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DDE02_15810	COG2814	Major facilitator Superfamily
DDE02_15815	COG1960	acyl-CoA dehydrogenase activity
DDE02_15820	COG0583	DNA-binding transcription factor activity
DDE02_15825	COG1063	alcohol dehydrogenase
DDE02_15855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DDE02_15860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DDE02_15865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDE02_15885	COG2132	Multicopper oxidase
DDE02_15895	COG0561	phosphatase activity
DDE02_15900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDE02_15910	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DDE02_15925	COG1214	PFAM Peptidase M22, glycoprotease
DDE02_15985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DDE02_15990	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DDE02_15995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDE02_16055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDE02_16065	COG1846	Transcriptional regulator
DDE02_16070	COG1764	response to oxidative stress
DDE02_16110	COG0037	tRNA processing
DDE02_16120	COG0248	Ppx GppA phosphatase
DDE02_16150	COG0072	phenylalanine-tRNA ligase activity
DDE02_16175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDE02_16190	COG1238	metal cluster binding
DDE02_16195	COG0625	glutathione transferase activity
DDE02_16215	COG0318	PFAM AMP-dependent synthetase and ligase
DDE02_16220	COG3028	Belongs to the UPF0307 family
DDE02_16225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDE02_16245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DDE02_16250	COG0617	tRNA 3'-terminal CCA addition
DDE02_16255	COG1555	photosystem II stabilization
DDE02_16260	COG3956	TIGRFAM MazG family protein
DDE02_16265	COG4221	oxidoreductase activity
DDE02_16270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDE02_16285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDE02_16290	COG0784	Response regulator, receiver
DDE02_16290	COG2205	protein histidine kinase activity
DDE02_16290	COG5002	protein histidine kinase activity
DDE02_16295	COG1024	Enoyl-CoA hydratase
DDE02_16300	COG2084	Dehydrogenase
DDE02_16305	COG3622	Belongs to the hyi family
DDE02_16340	COG0697	spore germination
DDE02_16350	COG2814	Major facilitator Superfamily
DDE02_16385	COG0789	Transcriptional regulator
DDE02_16410	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DDE02_16435	COG2132	Multicopper oxidase
DDE02_16450	COG2205	protein histidine kinase activity
DDE02_16455	COG2217	Heavy metal translocating P-type atpase
DDE02_16535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DDE02_16550	COG0583	DNA-binding transcription factor activity
DDE02_16560	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DDE02_16570	COG0084	hydrolase, TatD family'
DDE02_16585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DDE02_16605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DDE02_16610	COG0440	acetolactate synthase activity
DDE02_16615	COG0028	Belongs to the TPP enzyme family
DDE02_16635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DDE02_16640	COG0577	efflux transmembrane transporter activity
DDE02_16640	COG1136	(ABC) transporter
DDE02_16670	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DDE02_16675	COG1162	GTPase activity
DDE02_16685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DDE02_16705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DDE02_16725	COG1426	Protein conserved in bacteria
DDE02_16760	COG0793	Belongs to the peptidase S41A family
DDE02_16775	COG2267	carboxylic ester hydrolase activity
DDE02_16785	COG1012	belongs to the aldehyde dehydrogenase family
DDE02_16790	COG3265	gluconokinase activity
DDE02_16800	COG0800	Aldolase
DDE02_16815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DDE02_16820	COG0280	phosphate acetyltransferase
DDE02_16820	COG0857	belongs to the CobB CobQ family
DDE02_16825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DDE02_16825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DDE02_16845	COG0740	serine-type endopeptidase activity
DDE02_16855	COG4774	siderophore transport
DDE02_16865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDE02_16875	COG2813	Specifically methylates the guanine in position
DDE02_16875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDE02_16975	COG0788	formyltetrahydrofolate deformylase activity
DDE02_17000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDE02_17000	COG4651	solute:proton antiporter activity
DDE02_17020	COG0724	RNA recognition motif
DDE02_17025	COG0210	DNA helicase
DDE02_17050	COG1733	regulation of RNA biosynthetic process
DDE02_17060	COG2900	Belongs to the SlyX family
DDE02_17065	COG0488	(ABC) transporter
DDE02_17075	COG1560	Kdo2-lipid A biosynthetic process
DDE02_17085	COG1301	dicarboxylic acid transport
DDE02_17140	COG0473	3-isopropylmalate dehydrogenase activity
DDE02_17165	COG0583	DNA-binding transcription factor activity
DDE02_17205	COG0583	DNA-binding transcription factor activity
DDE02_17215	COG0625	glutathione transferase activity
DDE02_17220	COG2378	regulation of single-species biofilm formation
DDE02_17225	COG0546	phosphoglycolate phosphatase activity
DDE02_17240	COG1530	ribonuclease E activity
DDE02_17245	COG0318	PFAM AMP-dependent synthetase and ligase
DDE02_17260	COG0583	DNA-binding transcription factor activity
DDE02_17265	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_17270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDE02_17280	COG0534	Mate efflux family protein
DDE02_17295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DDE02_17320	COG0493	'glutamate synthase
DDE02_17330	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DDE02_17335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDE02_17350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDE02_17360	COG0644	oxidoreductase
DDE02_17360	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DDE02_17375	COG4535	Mg2 and Co2 transporter CorC
DDE02_17385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDE02_17405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDE02_17415	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DDE02_17425	COG0484	heat shock protein binding
DDE02_17430	COG0789	Transcriptional regulator
DDE02_17435	COG0598	Magnesium transport protein CorA
DDE02_17440	COG1185	polyribonucleotide nucleotidyltransferase activity
DDE02_17450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DDE02_17455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDE02_17460	COG1074	ATP-dependent DNA helicase activity
DDE02_17465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DDE02_17485	COG2226	methyltransferase
DDE02_17500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_17510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DDE02_17525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDE02_17525	COG2111	Na H antiporter
DDE02_17530	COG1006	Multisubunit Na H antiporter MnhC subunit
DDE02_17535	COG0651	ATP synthesis coupled electron transport
DDE02_17540	COG1863	multisubunit Na H antiporter MnhE subunit
DDE02_17545	COG2212	antiporter activity
DDE02_17550	COG1320	monovalent cation:proton antiporter activity
DDE02_17555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DDE02_17565	COG0195	Participates in both transcription termination and antitermination
DDE02_17615	COG0237	dephospho-CoA kinase activity
DDE02_17625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDE02_17640	COG0497	DNA recombination
DDE02_17650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDE02_17685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDE02_17685	COG2169	Transcriptional regulator
DDE02_17690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDE02_17760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DDE02_17775	COG0326	Molecular chaperone. Has ATPase activity
DDE02_17790	COG2056	Na+-H+ antiporter family
DDE02_17860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDE02_17890	COG0546	phosphoglycolate phosphatase activity
DDE02_17895	COG1716	ATPase activity
DDE02_17940	COG0181	hydroxymethylbilane synthase activity
DDE02_17950	COG3275	phosphorelay sensor kinase activity
DDE02_17970	COG1538	Outer membrane efflux protein
DDE02_17980	COG0697	spore germination
DDE02_18000	COG0494	nUDIX hydrolase
DDE02_18005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DDE02_18010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DDE02_18015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDE02_18020	COG0772	Belongs to the SEDS family
DDE02_18045	COG4974	Belongs to the 'phage' integrase family
DDE02_18050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDE02_18060	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DDE02_18070	COG2197	response regulator
DDE02_18085	COG0793	Belongs to the peptidase S41A family
DDE02_18090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DDE02_18095	COG0795	lipopolysaccharide-transporting ATPase activity
DDE02_18135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDE02_18135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DDE02_18145	COG0004	ammonium transporteR
DDE02_18150	COG0347	Belongs to the P(II) protein family
DDE02_18160	COG0606	chelatase, subunit chli
DDE02_18165	COG0431	NADPH-dependent FMN reductase
DDE02_18170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_18175	COG0235	Class ii aldolase
DDE02_18180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDE02_18200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DDE02_18215	COG0318	PFAM AMP-dependent synthetase and ligase
DDE02_18225	COG0477	Major facilitator Superfamily
DDE02_18230	COG2860	membrane
DDE02_18240	COG1253	flavin adenine dinucleotide binding
DDE02_18250	COG2814	Major facilitator Superfamily
DDE02_18260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDE02_18300	COG0655	NAD(P)H dehydrogenase (quinone) activity
DDE02_18315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDE02_18345	COG1309	transcriptional regulator
DDE02_18380	COG0758	DNA mediated transformation
DDE02_18390	COG0697	spore germination
DDE02_18395	COG1309	transcriptional regulator
DDE02_18410	COG0386	Belongs to the glutathione peroxidase family
DDE02_18425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDE02_18435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDE02_18475	COG1121	(ABC) transporter
DDE02_18480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDE02_18485	COG1280	lysine exporter protein (LysE YggA)
DDE02_18490	COG2837	iron assimilation
DDE02_18495	COG0281	malic enzyme
DDE02_18540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDE02_18540	COG0519	Catalyzes the synthesis of GMP from XMP
DDE02_18545	COG4399	Belongs to the UPF0754 family
DDE02_18550	COG2259	Doxx family
DDE02_18555	COG0586	Pfam SNARE associated Golgi protein
DDE02_18570	COG1192	Involved in chromosome partitioning
DDE02_18580	COG0271	Belongs to the BolA IbaG family
DDE02_18620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDE02_18620	COG3321	synthase
DDE02_18620	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DDE02_18620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDE02_18625	COG1960	acyl-CoA dehydrogenase activity
DDE02_18630	COG0318	PFAM AMP-dependent synthetase and ligase
DDE02_18635	COG2197	response regulator
DDE02_18645	COG3916	Acyl-homoserine-lactone synthase
DDE02_18650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE02_18660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDE02_18665	COG1113	amino acid transport
DDE02_18670	COG0697	spore germination
DDE02_18675	COG0477	Major facilitator Superfamily
DDE02_18680	COG1024	Enoyl-CoA hydratase
DDE02_18685	COG1024	Enoyl-CoA hydratase
DDE02_18690	COG1960	acyl-CoA dehydrogenase activity
DDE02_18695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DDE02_18715	COG1113	amino acid transport
DDE02_18720	COG1113	amino acid transport
DDE02_18725	COG0251	oxidation-reduction process
DDE02_18765	COG0564	pseudouridine synthase activity
DDE02_18785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDE02_18810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDE02_18885	COG1051	belongs to the nudix hydrolase family
DDE02_18905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DDE02_18920	COG1802	Transcriptional regulator
DDE02_18930	COG1448	Aminotransferase
DDE02_18935	COG0277	FAD linked oxidase domain protein
DDE02_18945	COG2186	Transcriptional regulator
DDE02_18955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDE02_18970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDE02_18975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DDE02_19000	COG1215	transferase activity, transferring glycosyl groups
DDE02_19015	COG1091	dTDP-4-dehydrorhamnose reductase activity
DDE02_19025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDE02_19045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DDE02_19075	COG0728	peptidoglycan biosynthetic process
DDE02_19080	COG3023	N-Acetylmuramoyl-L-alanine amidase
DDE02_19140	COG0546	phosphoglycolate phosphatase activity
DDE02_19145	COG1028	Short-chain dehydrogenase reductase Sdr
DDE02_19160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DDE02_19160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DDE02_19165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDE02_19170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDE02_19175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DDE02_19180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDE02_19185	COG1116	anion transmembrane transporter activity
DDE02_19190	COG1309	transcriptional regulator
DDE02_19195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDE02_19205	COG0196	riboflavin kinase activity
DDE02_19210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDE02_19220	COG1047	Peptidyl-prolyl cis-trans
DDE02_19260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDE02_19265	COG0657	acetylesterase activity
DDE02_19315	COG2951	lytic endotransglycosylase activity
DDE02_19320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DDE02_19335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDE02_19345	COG0671	phosphoesterase, PA-phosphatase related
DDE02_19350	COG0861	Integral membrane protein TerC family
DDE02_19360	COG0754	glutathionylspermidine amidase activity
DDE02_19370	COG0402	S-adenosylhomocysteine deaminase activity
DDE02_19385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DDE02_19390	COG1230	cation diffusion facilitator family transporter
DDE02_19405	COG0706	membrane insertase activity
DDE02_19430	COG0592	DNA-directed DNA polymerase activity
DDE02_19440	COG0187	DNA topoisomerase II activity
DDE02_19455	COG0488	(ABC) transporter
DDE02_19480	COG0596	Alpha beta hydrolase
DDE02_19485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DDE02_19490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDE02_19525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDE02_19575	COG1192	Involved in chromosome partitioning
DDE02_19585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDE02_19630	COG0739	heme binding
DDE02_19875	COG0501	Belongs to the peptidase M48B family
DDE02_19910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DDE02_19965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_19990	COG0556	nucleotide-excision repair
DDE02_20000	COG1271	oxidase subunit
DDE02_20005	COG1294	oxidase, subunit
DDE02_20020	COG2918	glutathione biosynthetic process
DDE02_20035	COG3791	Glutathione-dependent formaldehyde-activating
DDE02_20050	COG1252	NADH dehydrogenase
DDE02_20135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDE02_20185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDE02_20270	COG0789	Transcriptional regulator
DDE02_20295	COG0582	viral genome integration into host DNA
DDE02_20310	COG2130	NADP-dependent
DDE02_20315	COG1309	transcriptional regulator
DDE02_20325	COG1902	pentaerythritol trinitrate reductase activity
DDE02_20335	COG1979	alcohol dehydrogenase
DDE02_20350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DDE02_20425	COG0583	DNA-binding transcription factor activity
DDE02_20440	COG3248	Nucleoside-binding outer membrane protein
DDE02_20445	COG2233	PERMEase
DDE02_20455	COG0583	DNA-binding transcription factor activity
DDE02_20460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_20465	COG4266	Belongs to the allantoicase family
DDE02_20480	COG2233	PERMEase
DDE02_20485	COG2351	hydroxyisourate hydrolase activity
DDE02_20550	COG0789	Transcriptional regulator
DDE02_20570	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DDE02_20575	COG0659	secondary active sulfate transmembrane transporter activity
DDE02_20635	COG1373	ATPase (AAA superfamily
DDE02_20720	COG2184	nucleotidyltransferase activity
DDE02_20765	COG1309	transcriptional regulator
DDE02_20800	COG0633	Ferredoxin
DDE02_20805	COG2207	Transcriptional regulator
DDE02_21050	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
DDE02_21080	COG4221	oxidoreductase activity
DDE02_21085	COG0583	DNA-binding transcription factor activity
DDE02_21090	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DDE02_21095	COG0604	alcohol dehydrogenase
DDE02_21095	COG3321	synthase
DDE02_21110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DDE02_21125	COG1979	alcohol dehydrogenase
DDE02_21135	COG1902	pentaerythritol trinitrate reductase activity
DDE02_21145	COG1309	transcriptional regulator
DDE02_21150	COG2130	NADP-dependent
DDE02_21165	COG0582	viral genome integration into host DNA
DDE02_21190	COG0789	Transcriptional regulator
DDE02_21205	COG0659	secondary active sulfate transmembrane transporter activity
DDE02_21210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DDE02_21230	COG0789	Transcriptional regulator
DDE02_21295	COG2351	hydroxyisourate hydrolase activity
DDE02_21300	COG2233	PERMEase
DDE02_21315	COG4266	Belongs to the allantoicase family
DDE02_21320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DDE02_21325	COG0583	DNA-binding transcription factor activity
DDE02_21335	COG2233	PERMEase
DDE02_21340	COG3248	Nucleoside-binding outer membrane protein
DDE02_21355	COG0583	DNA-binding transcription factor activity
DDE02_21450	COG2207	Transcriptional regulator
DDE02_21455	COG0633	Ferredoxin
DDE02_21490	COG1309	transcriptional regulator
DDE02_21545	COG2184	nucleotidyltransferase activity
DDE02_21630	COG1373	ATPase (AAA superfamily
DDE02_21810	COG4679	PFAM Phage derived protein Gp49-like (DUF891)