locus-tag	class	description
LG653_00035	COG2199	diguanylate cyclase activity
LG653_00040	COG2885	chlorophyll binding
LG653_00040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LG653_00045	COG1408	metallophosphoesterase
LG653_00050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG653_00060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LG653_00080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LG653_00085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LG653_00090	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LG653_00095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LG653_00100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LG653_00110	COG2969	positive regulation of protein catabolic process
LG653_00150	COG1960	acyl-CoA dehydrogenase activity
LG653_00155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG653_00170	COG1309	transcriptional regulator
LG653_00175	COG1960	acyl-CoA dehydrogenase activity
LG653_00220	COG1183	phosphatidylcholine synthase activity
LG653_00225	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LG653_00255	COG0739	heme binding
LG653_00255	COG1196	nuclear chromosome segregation
LG653_00255	COG0741	lytic transglycosylase activity
LG653_00265	COG1702	phosphate starvation-inducible protein PhoH
LG653_00300	COG1295	ribonuclease BN
LG653_00305	COG0179	Fumarylacetoacetate (FAA) hydrolase
LG653_00335	COG2826	transposase and inactivated derivatives, IS30 family
LG653_00360	COG0557	exoribonuclease II activity
LG653_00365	COG0339	signal peptide processing
LG653_00370	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LG653_00400	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LG653_00405	COG1960	acyl-CoA dehydrogenase activity
LG653_00540	COG0088	Forms part of the polypeptide exit tunnel
LG653_00545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LG653_00560	COG0626	cystathionine gamma-synthase activity
LG653_00565	COG0433	COG0433 Predicted ATPase
LG653_00575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG653_00575	COG1017	nitric oxide dioxygenase activity
LG653_00580	COG1959	2 iron, 2 sulfur cluster binding
LG653_00595	COG1301	dicarboxylic acid transport
LG653_00600	COG1946	Acyl-CoA thioesterase
LG653_00620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LG653_00625	COG1040	competence protein
LG653_00630	COG0494	nUDIX hydrolase
LG653_00640	COG0598	Magnesium transport protein CorA
LG653_00650	COG2854	intermembrane phospholipid transfer
LG653_00660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LG653_00665	COG1127	ABC transporter
LG653_00675	COG0513	Belongs to the DEAD box helicase family
LG653_00695	COG0408	coproporphyrinogen oxidase activity
LG653_00710	COG1960	acyl-CoA dehydrogenase activity
LG653_00720	COG1983	PspC domain protein
LG653_00725	COG0517	IMP dehydrogenase activity
LG653_00745	COG0752	glycyl-tRNA synthetase alpha subunit
LG653_00770	COG0583	DNA-binding transcription factor activity
LG653_00810	COG1012	belongs to the aldehyde dehydrogenase family
LG653_00820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG653_00825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG653_00830	COG0833	amino acid
LG653_00860	COG1192	Involved in chromosome partitioning
LG653_00865	COG0628	permease
LG653_00875	COG1289	transmembrane transporter activity
LG653_00890	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG653_00895	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LG653_00915	COG0277	FAD linked oxidase domain protein
LG653_00920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LG653_00925	COG5006	permease, DMT superfamily
LG653_00945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LG653_00950	COG5380	lipid catabolic process
LG653_00960	COG0335	large ribosomal subunit rRNA binding
LG653_00970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LG653_01020	COG0194	GDP metabolic process
LG653_01035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LG653_01060	COG3307	-O-antigen
LG653_01080	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LG653_01085	COG1704	LemA family
LG653_01095	COG0493	'glutamate synthase
LG653_01100	COG0067	glutamate synthase
LG653_01100	COG0069	glutamate synthase activity
LG653_01100	COG0070	glutamate synthase
LG653_01150	COG2226	methyltransferase
LG653_01165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LG653_01170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LG653_01215	COG0833	amino acid
LG653_01300	COG0488	(ABC) transporter
LG653_01305	COG2873	o-acetylhomoserine
LG653_01310	COG4221	oxidoreductase activity
LG653_01315	COG0659	secondary active sulfate transmembrane transporter activity
LG653_01340	COG0427	acetyl-CoA hydrolase
LG653_01370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LG653_01380	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LG653_01400	COG2329	Antibiotic biosynthesis monooxygenase
LG653_01415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG653_01475	COG2207	Transcriptional regulator
LG653_01480	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LG653_01490	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG653_01495	COG1733	regulation of RNA biosynthetic process
LG653_01510	COG1309	transcriptional regulator
LG653_01530	COG0667	Aldo Keto reductase
LG653_01550	COG0583	DNA-binding transcription factor activity
LG653_01555	COG2814	Major facilitator Superfamily
LG653_01595	COG1335	isochorismatase
LG653_01605	COG1012	belongs to the aldehyde dehydrogenase family
LG653_01610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LG653_01630	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LG653_01645	COG2814	Major facilitator Superfamily
LG653_01655	COG0351	phosphomethylpyrimidine kinase
LG653_01655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LG653_01655	COG0352	thiamine-phosphate diphosphorylase activity
LG653_01675	COG1309	transcriptional regulator
LG653_01695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LG653_01705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG653_01710	COG3162	membrane
LG653_01715	COG2198	Histidine kinase
LG653_01715	COG0784	Response regulator, receiver
LG653_01715	COG2205	protein histidine kinase activity
LG653_01740	COG1522	sequence-specific DNA binding
LG653_01745	COG1335	isochorismatase
LG653_01750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG653_01760	COG0668	transmembrane transport
LG653_01770	COG1519	Transferase
LG653_01775	COG1902	pentaerythritol trinitrate reductase activity
LG653_01795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LG653_01815	COG0426	domain, Protein
LG653_01815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG653_01820	COG4774	siderophore transport
LG653_01825	COG2119	membrane
LG653_01835	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG653_01845	COG4942	peptidase
LG653_01860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LG653_01870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LG653_01890	COG0189	ligase activity
LG653_01910	COG0708	Exodeoxyribonuclease III
LG653_01915	COG1393	Belongs to the ArsC family
LG653_01930	COG3706	GGDEF domain
LG653_01965	COG2351	hydroxyisourate hydrolase activity
LG653_01970	COG2233	PERMEase
LG653_01980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG653_01990	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LG653_02000	COG3150	esterase
LG653_02010	COG2826	transposase and inactivated derivatives, IS30 family
LG653_02055	COG2918	glutathione biosynthetic process
LG653_02070	COG2733	membrane
LG653_02075	COG0436	Aminotransferase
LG653_02080	COG0534	Mate efflux family protein
LG653_02180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LG653_02185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LG653_02195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LG653_02215	COG1280	lysine exporter protein (LysE YggA)
LG653_02225	COG0546	phosphoglycolate phosphatase activity
LG653_02235	COG0010	Belongs to the arginase family
LG653_02265	COG2188	Transcriptional regulator
LG653_02275	COG0523	cobalamin synthesis protein
LG653_02285	COG1113	amino acid transport
LG653_02295	COG0625	glutathione transferase activity
LG653_02300	COG0346	lactoylglutathione lyase activity
LG653_02315	COG1683	Conserved Protein
LG653_02320	COG0534	Mate efflux family protein
LG653_02325	COG0385	Bile acid
LG653_02330	COG1335	isochorismatase
LG653_02335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG653_02355	COG2116	formate transmembrane transporter activity
LG653_02360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LG653_02365	COG2133	pyrroloquinoline quinone binding
LG653_02370	COG2983	Belongs to the UPF0260 family
LG653_02375	COG5487	UPF0391 membrane protein
LG653_02390	COG1194	a g-specific adenine glycosylase
LG653_02405	COG2818	Glycosylase
LG653_02410	COG1064	alcohol dehydrogenase
LG653_02415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_02430	COG0583	DNA-binding transcription factor activity
LG653_02435	COG0656	L-ascorbic acid biosynthetic process
LG653_02440	COG2814	Major facilitator Superfamily
LG653_02475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_02490	COG2233	PERMEase
LG653_02530	COG0733	neurotransmitter:sodium symporter activity
LG653_02540	COG0625	glutathione transferase activity
LG653_02570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LG653_02575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LG653_02580	COG0596	Alpha beta hydrolase
LG653_02605	COG0488	(ABC) transporter
LG653_02620	COG0187	DNA topoisomerase II activity
LG653_02630	COG0592	DNA-directed DNA polymerase activity
LG653_02655	COG0706	membrane insertase activity
LG653_02670	COG1230	cation diffusion facilitator family transporter
LG653_02675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG653_02690	COG0402	S-adenosylhomocysteine deaminase activity
LG653_02700	COG0754	glutathionylspermidine amidase activity
LG653_02715	COG0861	Integral membrane protein TerC family
LG653_02720	COG0671	phosphoesterase, PA-phosphatase related
LG653_02730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LG653_02745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LG653_02750	COG2951	lytic endotransglycosylase activity
LG653_02780	COG0583	DNA-binding transcription factor activity
LG653_02800	COG0657	acetylesterase activity
LG653_02805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LG653_02845	COG1047	Peptidyl-prolyl cis-trans
LG653_02855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LG653_02860	COG0196	riboflavin kinase activity
LG653_02870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LG653_02875	COG1309	transcriptional regulator
LG653_02880	COG1116	anion transmembrane transporter activity
LG653_02885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG653_02890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG653_02895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG653_02900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG653_02905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LG653_02905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LG653_02920	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_02925	COG0546	phosphoglycolate phosphatase activity
LG653_02980	COG3023	N-Acetylmuramoyl-L-alanine amidase
LG653_02985	COG0728	peptidoglycan biosynthetic process
LG653_03010	COG1596	polysaccharide export
LG653_03015	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LG653_03025	COG1091	dTDP-4-dehydrorhamnose reductase activity
LG653_03030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LG653_03040	COG2244	polysaccharide biosynthetic process
LG653_03045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LG653_03070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LG653_03075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LG653_03095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG653_03105	COG2186	Transcriptional regulator
LG653_03115	COG0277	FAD linked oxidase domain protein
LG653_03120	COG1448	Aminotransferase
LG653_03130	COG1802	Transcriptional regulator
LG653_03145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LG653_03235	COG0564	pseudouridine synthase activity
LG653_03275	COG0251	oxidation-reduction process
LG653_03285	COG1113	amino acid transport
LG653_03305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG653_03310	COG1960	acyl-CoA dehydrogenase activity
LG653_03315	COG1024	Enoyl-CoA hydratase
LG653_03320	COG1024	Enoyl-CoA hydratase
LG653_03325	COG0477	Major facilitator Superfamily
LG653_03330	COG0697	spore germination
LG653_03335	COG1113	amino acid transport
LG653_03340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG653_03350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_03355	COG3916	Acyl-homoserine-lactone synthase
LG653_03365	COG2197	response regulator
LG653_03370	COG0318	PFAM AMP-dependent synthetase and ligase
LG653_03375	COG1960	acyl-CoA dehydrogenase activity
LG653_03380	COG3321	synthase
LG653_03380	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LG653_03380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LG653_03380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LG653_03420	COG0271	Belongs to the BolA IbaG family
LG653_03430	COG1192	Involved in chromosome partitioning
LG653_03445	COG0586	Pfam SNARE associated Golgi protein
LG653_03450	COG2259	Doxx family
LG653_03455	COG4399	Belongs to the UPF0754 family
LG653_03460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG653_03460	COG0519	Catalyzes the synthesis of GMP from XMP
LG653_03505	COG0281	malic enzyme
LG653_03510	COG2837	iron assimilation
LG653_03515	COG1280	lysine exporter protein (LysE YggA)
LG653_03520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LG653_03525	COG1121	(ABC) transporter
LG653_03565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LG653_03575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LG653_03590	COG0386	Belongs to the glutathione peroxidase family
LG653_03605	COG1309	transcriptional regulator
LG653_03610	COG0697	spore germination
LG653_03620	COG0758	DNA mediated transformation
LG653_03685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG653_03700	COG0655	NAD(P)H dehydrogenase (quinone) activity
LG653_03740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG653_03750	COG2814	Major facilitator Superfamily
LG653_03760	COG1253	flavin adenine dinucleotide binding
LG653_03770	COG2860	membrane
LG653_03775	COG0477	Major facilitator Superfamily
LG653_03785	COG0318	PFAM AMP-dependent synthetase and ligase
LG653_03800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LG653_03820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG653_03825	COG0235	Class ii aldolase
LG653_03830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_03835	COG0431	NADPH-dependent FMN reductase
LG653_03840	COG0606	chelatase, subunit chli
LG653_03850	COG0347	Belongs to the P(II) protein family
LG653_03855	COG0004	ammonium transporteR
LG653_03865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG653_03865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG653_03905	COG0795	lipopolysaccharide-transporting ATPase activity
LG653_03910	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LG653_03915	COG0793	Belongs to the peptidase S41A family
LG653_03930	COG2197	response regulator
LG653_03940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LG653_03950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG653_03955	COG4974	Belongs to the 'phage' integrase family
LG653_03980	COG0772	Belongs to the SEDS family
LG653_03985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LG653_03990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG653_03995	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LG653_04000	COG0494	nUDIX hydrolase
LG653_04020	COG0697	spore germination
LG653_04030	COG1538	Outer membrane efflux protein
LG653_04050	COG3275	phosphorelay sensor kinase activity
LG653_04060	COG0181	hydroxymethylbilane synthase activity
LG653_04105	COG1716	ATPase activity
LG653_04110	COG0546	phosphoglycolate phosphatase activity
LG653_04140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LG653_04210	COG2056	Na+-H+ antiporter family
LG653_04225	COG0326	Molecular chaperone. Has ATPase activity
LG653_04240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LG653_04305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LG653_04315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LG653_04315	COG2169	Transcriptional regulator
LG653_04350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LG653_04360	COG0497	DNA recombination
LG653_04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG653_04385	COG0237	dephospho-CoA kinase activity
LG653_04435	COG0195	Participates in both transcription termination and antitermination
LG653_04445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LG653_04450	COG1320	monovalent cation:proton antiporter activity
LG653_04455	COG2212	antiporter activity
LG653_04460	COG1863	multisubunit Na H antiporter MnhE subunit
LG653_04465	COG0651	ATP synthesis coupled electron transport
LG653_04470	COG1006	Multisubunit Na H antiporter MnhC subunit
LG653_04475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LG653_04475	COG2111	Na H antiporter
LG653_04490	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LG653_04500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG653_04505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LG653_04515	COG2226	methyltransferase
LG653_04535	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LG653_04540	COG1074	ATP-dependent DNA helicase activity
LG653_04545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LG653_04550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG653_04560	COG1185	polyribonucleotide nucleotidyltransferase activity
LG653_04570	COG0789	Transcriptional regulator
LG653_04575	COG0484	heat shock protein binding
LG653_04585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LG653_04595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LG653_04615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG653_04625	COG4535	Mg2 and Co2 transporter CorC
LG653_04640	COG0644	oxidoreductase
LG653_04640	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LG653_04650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LG653_04665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG653_04670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LG653_04680	COG0493	'glutamate synthase
LG653_04705	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LG653_04720	COG0534	Mate efflux family protein
LG653_04730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG653_04735	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_04740	COG0583	DNA-binding transcription factor activity
LG653_04755	COG0318	PFAM AMP-dependent synthetase and ligase
LG653_04760	COG1530	ribonuclease E activity
LG653_04770	COG0546	phosphoglycolate phosphatase activity
LG653_04775	COG2378	regulation of single-species biofilm formation
LG653_04780	COG0625	glutathione transferase activity
LG653_04790	COG2826	transposase and inactivated derivatives, IS30 family
LG653_04795	COG0583	DNA-binding transcription factor activity
LG653_04840	COG0583	DNA-binding transcription factor activity
LG653_04865	COG0473	3-isopropylmalate dehydrogenase activity
LG653_04920	COG1301	dicarboxylic acid transport
LG653_04930	COG1560	Kdo2-lipid A biosynthetic process
LG653_04940	COG0488	(ABC) transporter
LG653_04945	COG2900	Belongs to the SlyX family
LG653_04950	COG0604	alcohol dehydrogenase
LG653_04955	COG1733	regulation of RNA biosynthetic process
LG653_04980	COG0210	DNA helicase
LG653_04985	COG0724	RNA recognition motif
LG653_05005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LG653_05005	COG4651	solute:proton antiporter activity
LG653_05030	COG0788	formyltetrahydrofolate deformylase activity
LG653_05130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG653_05130	COG2813	Specifically methylates the guanine in position
LG653_05140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG653_05150	COG4774	siderophore transport
LG653_05160	COG0740	serine-type endopeptidase activity
LG653_05180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LG653_05180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LG653_05185	COG0280	phosphate acetyltransferase
LG653_05185	COG0857	belongs to the CobB CobQ family
LG653_05190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LG653_05205	COG0800	Aldolase
LG653_05215	COG3265	gluconokinase activity
LG653_05220	COG1012	belongs to the aldehyde dehydrogenase family
LG653_05230	COG2267	carboxylic ester hydrolase activity
LG653_05245	COG0793	Belongs to the peptidase S41A family
LG653_05280	COG1426	Protein conserved in bacteria
LG653_05300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LG653_05320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LG653_05330	COG1162	GTPase activity
LG653_05335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LG653_05365	COG1136	(ABC) transporter
LG653_05365	COG0577	efflux transmembrane transporter activity
LG653_05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_05390	COG0028	Belongs to the TPP enzyme family
LG653_05395	COG0440	acetolactate synthase activity
LG653_05400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LG653_05420	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LG653_05435	COG0084	hydrolase, TatD family'
LG653_05445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LG653_05455	COG0583	DNA-binding transcription factor activity
LG653_05470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG653_05555	COG2205	protein histidine kinase activity
LG653_05570	COG2132	Multicopper oxidase
LG653_05595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG653_05630	COG0640	Transcriptional regulator
LG653_05640	COG0798	PFAM Bile acid sodium symporter
LG653_05645	COG0431	NADPH-dependent FMN reductase
LG653_05650	COG0492	ferredoxin-NADP+ reductase activity
LG653_05655	COG2072	flavoprotein involved in K transport
LG653_05690	COG2814	Major facilitator Superfamily
LG653_05700	COG0697	spore germination
LG653_05730	COG3622	Belongs to the hyi family
LG653_05735	COG2084	Dehydrogenase
LG653_05740	COG1024	Enoyl-CoA hydratase
LG653_05745	COG0784	Response regulator, receiver
LG653_05745	COG2205	protein histidine kinase activity
LG653_05745	COG5002	protein histidine kinase activity
LG653_05750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG653_05765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LG653_05770	COG4221	oxidoreductase activity
LG653_05775	COG3956	TIGRFAM MazG family protein
LG653_05780	COG1555	photosystem II stabilization
LG653_05785	COG0617	tRNA 3'-terminal CCA addition
LG653_05790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LG653_05810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG653_05815	COG3028	Belongs to the UPF0307 family
LG653_05820	COG0318	PFAM AMP-dependent synthetase and ligase
LG653_05835	COG0625	glutathione transferase activity
LG653_05840	COG1238	metal cluster binding
LG653_05855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LG653_05880	COG0072	phenylalanine-tRNA ligase activity
LG653_05910	COG0248	Ppx GppA phosphatase
LG653_05920	COG0037	tRNA processing
LG653_05960	COG1764	response to oxidative stress
LG653_05965	COG1846	Transcriptional regulator
LG653_05975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG653_06035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LG653_06040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LG653_06045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LG653_06105	COG1214	PFAM Peptidase M22, glycoprotease
LG653_06130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LG653_06145	COG2132	Multicopper oxidase
LG653_06165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LG653_06170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LG653_06175	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LG653_06210	COG1063	alcohol dehydrogenase
LG653_06215	COG0583	DNA-binding transcription factor activity
LG653_06220	COG1960	acyl-CoA dehydrogenase activity
LG653_06225	COG2814	Major facilitator Superfamily
LG653_06230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LG653_06240	COG1309	transcriptional regulator
LG653_06255	COG1053	succinate dehydrogenase
LG653_06260	COG0583	DNA-binding transcription factor activity
LG653_06275	COG0583	DNA-binding transcription factor activity
LG653_06325	COG0583	DNA-binding transcription factor activity
LG653_06340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG653_06385	COG2826	transposase and inactivated derivatives, IS30 family
LG653_06410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LG653_06430	COG0745	RESPONSE REGULATOR receiver
LG653_06445	COG2199	diguanylate cyclase activity
LG653_06470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LG653_06500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LG653_06505	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LG653_06525	COG0583	DNA-binding transcription factor activity
LG653_06545	COG0668	transmembrane transport
LG653_06555	COG2081	HI0933 family
LG653_06560	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LG653_06595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG653_06595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG653_06605	COG0489	protein tyrosine kinase activity
LG653_06610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LG653_06660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG653_06670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LG653_06685	COG0730	response to heat
LG653_06695	COG1196	nuclear chromosome segregation
LG653_06715	COG2223	nitrite transmembrane transporter activity
LG653_06720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LG653_06730	COG0596	Alpha beta hydrolase
LG653_06730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG653_06730	COG2226	methyltransferase
LG653_06745	COG4106	trans-aconitate 2-methyltransferase activity
LG653_06760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LG653_06765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LG653_06770	COG0009	L-threonylcarbamoyladenylate synthase
LG653_06775	COG3101	peptidyl-lysine hydroxylation
LG653_06780	COG1399	metal-binding, possibly nucleic acid-binding protein
LG653_06805	COG1652	LysM domain
LG653_06810	COG0351	phosphomethylpyrimidine kinase
LG653_06810	COG0352	thiamine-phosphate diphosphorylase activity
LG653_06810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LG653_06820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG653_06850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LG653_06880	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LG653_06895	COG0358	DNA primase activity
LG653_06930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LG653_06950	COG0583	DNA-binding transcription factor activity
LG653_06955	COG0473	3-isopropylmalate dehydrogenase activity
LG653_06965	COG0657	acetylesterase activity
LG653_06970	COG4638	Rieske (2fe-2S)
LG653_06975	COG1012	belongs to the aldehyde dehydrogenase family
LG653_06995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LG653_06995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG653_07005	COG1981	membrane
LG653_07020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LG653_07030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LG653_07035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LG653_07050	COG0456	acetyltransferase
LG653_07060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LG653_07065	COG0492	ferredoxin-NADP+ reductase activity
LG653_07070	COG1674	ftsk spoiiie
LG653_07075	COG1280	lysine exporter protein (LysE YggA)
LG653_07095	COG2894	cell division
LG653_07110	COG0204	Acyl-transferase
LG653_07115	COG2885	chlorophyll binding
LG653_07120	COG0210	DNA helicase
LG653_07130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG653_07145	COG0121	glutamine amidotransferase
LG653_07160	COG2914	Belongs to the UPF0125 (RnfH) family
LG653_07165	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LG653_07170	COG0735	belongs to the Fur family
LG653_07195	COG0420	3'-5' exonuclease activity
LG653_07215	COG1090	epimerase
LG653_07230	COG2050	protein possibly involved in aromatic compounds catabolism
LG653_07240	COG2814	Major facilitator Superfamily
LG653_07245	COG0405	Gamma-glutamyltransferase
LG653_07260	COG2826	transposase and inactivated derivatives, IS30 family
LG653_07340	COG0477	Major facilitator Superfamily
LG653_07345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG653_07355	COG1595	DNA-templated transcription, initiation
LG653_07410	COG0531	amino acid
LG653_07415	COG2040	homocysteine
LG653_07440	COG1309	transcriptional regulator
LG653_07445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LG653_07450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LG653_07460	COG1607	acyl-coa hydrolase
LG653_07470	COG0523	cobalamin synthesis protein
LG653_07480	COG4681	YaeQ
LG653_07490	COG0726	polysaccharide deacetylase
LG653_07490	COG1649	PFAM Uncharacterised BCR, COG1649
LG653_07495	COG1215	transferase activity, transferring glycosyl groups
LG653_07505	COG1024	Enoyl-CoA hydratase
LG653_07520	COG1414	Transcriptional regulator
LG653_07540	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_07555	COG2271	Major facilitator Superfamily
LG653_07565	COG2267	carboxylic ester hydrolase activity
LG653_07570	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_07585	COG0028	Belongs to the TPP enzyme family
LG653_07595	COG0477	Major facilitator Superfamily
LG653_07600	COG0242	peptide deformylase activity
LG653_07605	COG2066	Belongs to the glutaminase family
LG653_07610	COG2207	Transcriptional regulator
LG653_07615	COG2223	nitrite transmembrane transporter activity
LG653_07640	COG0306	phosphate transporter
LG653_07660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG653_07705	COG4181	ATPase activity
LG653_07710	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LG653_07740	COG0583	DNA-binding transcription factor activity
LG653_07745	COG2267	carboxylic ester hydrolase activity
LG653_07750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG653_07755	COG1773	rubredoxin
LG653_07805	COG2851	Citrate transporter
LG653_07810	COG1253	flavin adenine dinucleotide binding
LG653_07825	COG3015	lipoprotein NlpE involved in copper resistance
LG653_07855	COG0804	urea catabolic process
LG653_07865	COG0830	nickel cation binding
LG653_07880	COG0742	ribosomal rna small subunit methyltransferase
LG653_07885	COG0768	penicillin binding
LG653_07910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LG653_07915	COG2878	Part of a membrane complex involved in electron transport
LG653_07920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG653_07930	COG3384	dioxygenase
LG653_07945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LG653_07985	COG0006	proline dipeptidase activity
LG653_07990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG653_07995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG653_08015	COG1279	arginine transmembrane transporter activity
LG653_08020	COG0583	DNA-binding transcription factor activity
LG653_08065	COG0741	lytic transglycosylase activity
LG653_08065	COG1388	LysM domain
LG653_08070	COG4166	transmembrane transport
LG653_08075	COG4174	ABC transporter (Permease)
LG653_08080	COG4239	(ABC) transporter, permease
LG653_08085	COG4172	Belongs to the ABC transporter superfamily
LG653_08110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LG653_08120	COG3706	GGDEF domain
LG653_08120	COG5001	Diguanylate cyclase
LG653_08120	COG4251	negative regulation of phosphorylation
LG653_08120	COG2203	Gaf domain
LG653_08130	COG1902	pentaerythritol trinitrate reductase activity
LG653_08130	COG0446	pyridine nucleotide-disulphide oxidoreductase
LG653_08150	COG4269	membrane
LG653_08190	COG1113	amino acid transport
LG653_08200	COG0531	amino acid
LG653_08220	COG1012	belongs to the aldehyde dehydrogenase family
LG653_08240	COG1113	amino acid transport
LG653_08265	COG0697	spore germination
LG653_08270	COG2721	sulfolactate sulfo-lyase activity
LG653_08275	COG2271	Major facilitator Superfamily
LG653_08280	COG4948	Mandelate Racemase Muconate Lactonizing
LG653_08290	COG1012	belongs to the aldehyde dehydrogenase family
LG653_08295	COG2186	Transcriptional regulator
LG653_08320	COG1960	acyl-CoA dehydrogenase activity
LG653_08335	COG1024	Enoyl-CoA hydratase
LG653_08340	COG2814	Major facilitator Superfamily
LG653_08355	COG2826	transposase and inactivated derivatives, IS30 family
LG653_08360	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LG653_08370	COG2826	transposase and inactivated derivatives, IS30 family
LG653_08380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG653_08395	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG653_08415	COG1944	ATP diphosphatase activity
LG653_08445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LG653_08460	COG0583	DNA-binding transcription factor activity
LG653_08465	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LG653_08470	COG2072	flavoprotein involved in K transport
LG653_08485	COG1309	transcriptional regulator
LG653_08490	COG1741	Belongs to the pirin family
LG653_08500	COG2252	PERMEase
LG653_08505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LG653_08510	COG3038	cytochrome b561
LG653_08520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LG653_08530	COG0527	aspartate kinase activity
LG653_08725	COG1598	PFAM Uncharacterised protein family UPF0150
LG653_08740	COG0739	heme binding
LG653_08740	COG0741	lytic transglycosylase activity
LG653_08740	COG1196	nuclear chromosome segregation
LG653_08790	COG1063	alcohol dehydrogenase
LG653_08795	COG3293	Transposase
LG653_08810	COG0582	viral genome integration into host DNA
LG653_08820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LG653_08830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LG653_08845	COG0667	Aldo Keto reductase
LG653_08860	COG1765	OsmC-like protein
LG653_08875	COG0542	response to heat
LG653_08890	COG2826	transposase and inactivated derivatives, IS30 family
LG653_08920	COG2885	chlorophyll binding
LG653_08930	COG0625	glutathione transferase activity
LG653_08935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LG653_08955	COG3634	alkyl hydroperoxide reductase activity
LG653_08980	COG1643	Atp-dependent helicase
LG653_08995	COG2814	Major facilitator Superfamily
LG653_09000	COG3135	benzoate transporter
LG653_09005	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_09010	COG0633	Ferredoxin
LG653_09010	COG0543	2 iron, 2 sulfur cluster binding
LG653_09020	COG4638	Rieske (2fe-2S)
LG653_09030	COG0583	DNA-binding transcription factor activity
LG653_09040	COG2871	sodium ion transport
LG653_09125	COG1570	exodeoxyribonuclease VII activity
LG653_09160	COG1280	lysine exporter protein (LysE YggA)
LG653_09165	COG1560	Kdo2-lipid A biosynthetic process
LG653_09170	COG1278	Cold shock
LG653_09195	COG2226	methyltransferase
LG653_09250	COG0668	transmembrane transport
LG653_09260	COG2814	Major facilitator Superfamily
LG653_09300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LG653_09310	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LG653_09315	COG1137	ATPase activity
LG653_09320	COG1538	Outer membrane efflux protein
LG653_09350	COG4122	O-methyltransferase activity
LG653_09360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LG653_09375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LG653_09390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG653_09395	COG0531	amino acid
LG653_09400	COG1522	sequence-specific DNA binding
LG653_09425	COG1733	regulation of RNA biosynthetic process
LG653_09430	COG0753	catalase activity
LG653_09435	COG3038	cytochrome b561
LG653_09455	COG2826	transposase and inactivated derivatives, IS30 family
LG653_09480	COG3712	iron ion homeostasis
LG653_09485	COG1595	DNA-templated transcription, initiation
LG653_09495	COG1051	belongs to the nudix hydrolase family
LG653_09510	COG1733	regulation of RNA biosynthetic process
LG653_09515	COG0702	epimerase
LG653_09570	COG3220	belongs to the UPF0276 family
LG653_09580	COG1595	DNA-templated transcription, initiation
LG653_09590	COG0583	DNA-binding transcription factor activity
LG653_09595	COG1914	H( )-stimulated, divalent metal cation uptake system
LG653_09615	COG4770	biotin carboxylase activity
LG653_09620	COG0038	chloride channel
LG653_09625	COG2831	hemolysin activation secretion protein
LG653_09635	COG2826	transposase and inactivated derivatives, IS30 family
LG653_09670	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG653_09675	COG1063	alcohol dehydrogenase
LG653_09690	COG4770	biotin carboxylase activity
LG653_09715	COG0666	response to abiotic stimulus
LG653_09720	COG0590	tRNA wobble adenosine to inosine editing
LG653_09725	COG2807	transmembrane transport
LG653_09740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_09745	COG2826	transposase and inactivated derivatives, IS30 family
LG653_09750	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LG653_09760	COG0789	Transcriptional regulator
LG653_09775	COG1760	l-serine dehydratase
LG653_09780	COG1012	belongs to the aldehyde dehydrogenase family
LG653_09780	COG2030	dehydratase
LG653_09785	COG3396	Phenylacetate-CoA oxygenase
LG653_09790	COG3460	Phenylacetate-CoA oxygenase
LG653_09795	COG3396	Phenylacetate-CoA oxygenase
LG653_09800	COG2151	metal-sulfur cluster biosynthetic enzyme
LG653_09805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG653_09810	COG1024	Enoyl-CoA hydratase
LG653_09815	COG1024	Enoyl-CoA hydratase
LG653_09820	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG653_09825	COG0183	Belongs to the thiolase family
LG653_09830	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LG653_09835	COG3327	negative regulation of DNA-templated transcription, initiation
LG653_09845	COG2050	protein possibly involved in aromatic compounds catabolism
LG653_09850	COG0583	DNA-binding transcription factor activity
LG653_09855	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_09885	COG0583	DNA-binding transcription factor activity
LG653_09895	COG1414	Transcriptional regulator
LG653_09900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG653_09915	COG1840	ABC-type Fe3 transport system, periplasmic component
LG653_09920	COG3842	ATPase activity
LG653_09935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LG653_09940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LG653_09945	COG2814	Major facilitator Superfamily
LG653_09950	COG1960	acyl-CoA dehydrogenase activity
LG653_09965	COG1024	Enoyl-CoA hydratase
LG653_09975	COG2814	Major facilitator Superfamily
LG653_09985	COG0183	Belongs to the thiolase family
LG653_09990	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG653_09995	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_10000	COG1024	Enoyl-CoA hydratase
LG653_10005	COG1960	acyl-CoA dehydrogenase activity
LG653_10010	COG2814	Major facilitator Superfamily
LG653_10015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LG653_10020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LG653_10030	COG2814	Major facilitator Superfamily
LG653_10040	COG1960	acyl-CoA dehydrogenase activity
LG653_10055	COG0583	DNA-binding transcription factor activity
LG653_10065	COG4770	biotin carboxylase activity
LG653_10070	COG1024	Enoyl-CoA hydratase
LG653_10075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG653_10080	COG1960	acyl-CoA dehydrogenase activity
LG653_10085	COG1309	transcriptional regulator
LG653_10090	COG0318	PFAM AMP-dependent synthetase and ligase
LG653_10105	COG2814	Major facilitator Superfamily
LG653_10115	COG0583	DNA-binding transcription factor activity
LG653_10165	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_10190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LG653_10210	COG2205	protein histidine kinase activity
LG653_10210	COG0784	Response regulator, receiver
LG653_10230	COG0765	amino acid transport
LG653_10235	COG0765	amino acid transport
LG653_10245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG653_10250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG653_10265	COG1280	lysine exporter protein (LysE YggA)
LG653_10270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LG653_10275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LG653_10280	COG1045	serine acetyltransferase
LG653_10295	COG0583	DNA-binding transcription factor activity
LG653_10315	COG0625	glutathione transferase activity
LG653_10320	COG0625	glutathione transferase activity
LG653_10325	COG0583	DNA-binding transcription factor activity
LG653_10335	COG1346	cytolysis
LG653_10360	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LG653_10365	COG3052	prosthetic group binding
LG653_10385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LG653_10405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_10415	COG1294	oxidase, subunit
LG653_10420	COG1271	oxidase subunit
LG653_10435	COG2826	transposase and inactivated derivatives, IS30 family
LG653_10445	COG0477	Major facilitator Superfamily
LG653_10455	COG4521	taurine ABC transporter
LG653_10460	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LG653_10465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG653_10470	COG2175	clavaminate synthase activity
LG653_10480	COG1953	Uracil, thiamine, allantoin
LG653_10490	COG0583	DNA-binding transcription factor activity
LG653_10500	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG653_10515	COG0640	Transcriptional regulator
LG653_10525	COG0798	PFAM Bile acid sodium symporter
LG653_10530	COG0431	NADPH-dependent FMN reductase
LG653_10535	COG0583	DNA-binding transcription factor activity
LG653_10550	COG3634	alkyl hydroperoxide reductase activity
LG653_10585	COG1301	dicarboxylic acid transport
LG653_10590	COG0436	Aminotransferase
LG653_10600	COG0386	Belongs to the glutathione peroxidase family
LG653_10605	COG2207	Transcriptional regulator
LG653_10605	COG1917	Cupin 2, conserved barrel domain protein
LG653_10640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LG653_10665	COG0012	GTP binding
LG653_10670	COG2011	ABC-type metal ion transport system permease component
LG653_10675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LG653_10685	COG1464	Belongs to the NlpA lipoprotein family
LG653_10695	COG2826	transposase and inactivated derivatives, IS30 family
LG653_10725	COG0765	amino acid transport
LG653_10730	COG0765	amino acid transport
LG653_10735	COG1126	abc transporter atp-binding protein
LG653_10745	COG1522	sequence-specific DNA binding
LG653_10760	COG1309	transcriptional regulator
LG653_10775	COG0583	DNA-binding transcription factor activity
LG653_10785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LG653_10795	COG0697	spore germination
LG653_10800	COG0583	DNA-binding transcription factor activity
LG653_10835	COG3539	Fimbrial protein
LG653_10860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LG653_10860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LG653_10905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LG653_10915	COG2353	YceI-like domain
LG653_10925	COG3698	Phosphodiester glycosidase
LG653_10940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LG653_10945	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LG653_10945	COG0506	proline dehydrogenase activity
LG653_10945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LG653_10955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG653_10960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LG653_10980	COG1132	(ABC) transporter
LG653_10985	COG3122	Protein conserved in bacteria
LG653_10990	COG3619	membrane
LG653_11000	COG0640	Transcriptional regulator
LG653_11010	COG2850	peptidyl-arginine hydroxylation
LG653_11015	COG0424	maF-like protein
LG653_11040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG653_11050	COG3178	'Phosphotransferase
LG653_11055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LG653_11065	COG1192	Involved in chromosome partitioning
LG653_11070	COG1475	DNA binding
LG653_11075	COG0811	peptide transport
LG653_11085	COG1132	(ABC) transporter
LG653_11090	COG1663	tetraacyldisaccharide 4'-kinase activity
LG653_11110	COG0084	hydrolase, TatD family'
LG653_11175	COG0776	regulation of translation
LG653_11190	COG2431	L-lysine efflux transmembrane transporter activity
LG653_11205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LG653_11210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LG653_11255	COG4166	transmembrane transport
LG653_11260	COG0339	signal peptide processing
LG653_11265	COG0601	transmembrane transport
LG653_11305	COG0702	epimerase
LG653_11310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LG653_11330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LG653_11360	COG0316	Belongs to the HesB IscA family
LG653_11365	COG0822	iron-sulfur transferase activity
LG653_11390	COG0776	regulation of translation
LG653_11395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG653_11400	COG2207	Transcriptional regulator
LG653_11405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG653_11410	COG1960	acyl-CoA dehydrogenase activity
LG653_11415	COG1960	acyl-CoA dehydrogenase activity
LG653_11430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LG653_11440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LG653_11455	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LG653_11475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LG653_11480	COG0730	response to heat
LG653_11505	COG4773	Receptor
LG653_11510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LG653_11570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LG653_11580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG653_11585	COG0583	DNA-binding transcription factor activity
LG653_11615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LG653_11625	COG0133	tryptophan synthase activity
LG653_11645	COG3706	GGDEF domain
LG653_11660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LG653_11665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG653_11670	COG0022	dehydrogenase e1 component
LG653_11675	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG653_11680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG653_11690	COG1063	alcohol dehydrogenase
LG653_11695	COG3781	membrane
LG653_11720	COG0730	response to heat
LG653_11735	COG2207	Transcriptional regulator
LG653_11735	COG3708	Transcriptional regulator
LG653_11740	COG1733	regulation of RNA biosynthetic process
LG653_11745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG653_11755	COG0477	Major facilitator Superfamily
LG653_11765	COG1027	Aspartate ammonia-lyase
LG653_11780	COG0583	DNA-binding transcription factor activity
LG653_11785	COG0583	DNA-binding transcription factor activity
LG653_11790	COG0183	Belongs to the thiolase family
LG653_11795	COG2031	fatty acid transporter
LG653_11810	COG0583	DNA-binding transcription factor activity
LG653_11850	COG2610	gluconate transmembrane transporter activity
LG653_11855	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_11860	COG2207	Transcriptional regulator
LG653_11880	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_11890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG653_11905	COG0543	2 iron, 2 sulfur cluster binding
LG653_11905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG653_11910	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LG653_11915	COG4638	Rieske (2fe-2S)
LG653_11925	COG0725	ABC transporter, periplasmic molybdate-binding protein
LG653_11930	COG4149	molybdate abc transporter
LG653_11935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LG653_11940	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_11945	COG1535	isochorismatase
LG653_11945	COG3433	isochorismatase activity
LG653_12000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG653_12005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_12010	COG0745	RESPONSE REGULATOR receiver
LG653_12015	COG2205	protein histidine kinase activity
LG653_12025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG653_12045	COG0753	catalase activity
LG653_12055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LG653_12080	COG3539	Fimbrial protein
LG653_12090	COG4628	conserved protein (DUF2132)
LG653_12100	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LG653_12150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LG653_12200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LG653_12210	COG1120	ATPase activity
LG653_12215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG653_12270	COG3210	domain, Protein
LG653_12275	COG2831	hemolysin activation secretion protein
LG653_12290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LG653_12295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LG653_12320	COG0583	DNA-binding transcription factor activity
LG653_12380	COG2826	transposase and inactivated derivatives, IS30 family
LG653_12390	COG1309	transcriptional regulator
LG653_12400	COG0318	PFAM AMP-dependent synthetase and ligase
LG653_12410	COG1960	acyl-CoA dehydrogenase activity
LG653_12420	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_12425	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_12430	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_12435	COG0583	DNA-binding transcription factor activity
LG653_12440	COG1309	transcriptional regulator
LG653_12480	COG1902	pentaerythritol trinitrate reductase activity
LG653_12480	COG0446	pyridine nucleotide-disulphide oxidoreductase
LG653_12500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG653_12510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG653_12520	COG2186	Transcriptional regulator
LG653_12525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LG653_12535	COG2233	PERMEase
LG653_12540	COG2351	hydroxyisourate hydrolase activity
LG653_12545	COG1012	belongs to the aldehyde dehydrogenase family
LG653_12565	COG2186	Transcriptional regulator
LG653_12575	COG0583	DNA-binding transcription factor activity
LG653_12580	COG4948	Mandelate Racemase Muconate Lactonizing
LG653_12585	COG4829	muconolactone delta-isomerase
LG653_12595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LG653_12600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LG653_12605	COG0183	Belongs to the thiolase family
LG653_12610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LG653_12615	COG1012	belongs to the aldehyde dehydrogenase family
LG653_12625	COG3733	amine oxidase
LG653_12635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG653_12645	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_12655	COG4638	Rieske (2fe-2S)
LG653_12675	COG0154	amidase activity
LG653_12685	COG2814	Major facilitator Superfamily
LG653_12710	COG1960	acyl-CoA dehydrogenase activity
LG653_12715	COG0583	DNA-binding transcription factor activity
LG653_12720	COG1414	Transcriptional regulator
LG653_12735	COG2391	methyltransferase activity
LG653_12745	COG4993	Dehydrogenase
LG653_12750	COG3659	wide pore channel activity
LG653_12755	COG3420	alginic acid biosynthetic process
LG653_12760	COG0710	3-dehydroquinate dehydratase activity
LG653_12765	COG3485	protocatechuate 3,4-dioxygenase
LG653_12770	COG3485	protocatechuate 3,4-dioxygenase
LG653_12775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG653_12780	COG2271	Major facilitator Superfamily
LG653_12785	COG0596	Alpha beta hydrolase
LG653_12790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LG653_12795	COG0183	Belongs to the thiolase family
LG653_12800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LG653_12805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LG653_12815	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LG653_12820	COG4773	Receptor
LG653_12830	COG2323	membrane
LG653_12835	COG0148	phosphopyruvate hydratase activity
LG653_12875	COG0446	pyridine nucleotide-disulphide oxidoreductase
LG653_12875	COG1902	pentaerythritol trinitrate reductase activity
LG653_12890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LG653_12900	COG0542	response to heat
LG653_12905	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LG653_12935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LG653_12940	COG0569	domain protein
LG653_12945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LG653_12960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG653_12970	COG1585	Membrane protein implicated in regulation of membrane protease activity
LG653_12985	COG1294	oxidase, subunit
LG653_12990	COG4890	Cyd operon protein YbgT
LG653_13015	COG0552	protein localization to endoplasmic reticulum
LG653_13040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LG653_13040	COG0517	IMP dehydrogenase activity
LG653_13045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG653_13050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LG653_13060	COG0583	DNA-binding transcription factor activity
LG653_13065	COG0024	Methionine aminopeptidase
LG653_13075	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LG653_13095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LG653_13095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG653_13100	COG1105	Belongs to the carbohydrate kinase PfkB family
LG653_13105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG653_13105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG653_13105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LG653_13140	COG0659	secondary active sulfate transmembrane transporter activity
LG653_13155	COG0657	acetylesterase activity
LG653_13160	COG1113	amino acid transport
LG653_13170	COG1522	sequence-specific DNA binding
LG653_13185	COG1011	Hydrolase
LG653_13190	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LG653_13200	COG2137	regulation of response to DNA damage stimulus
LG653_13215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LG653_13250	COG0575	Belongs to the CDS family
LG653_13255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LG653_13280	COG3852	Histidine kinase
LG653_13285	COG2204	response regulator
LG653_13355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LG653_13380	COG0697	spore germination
LG653_13385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_13395	COG0303	'Molybdopterin
LG653_13400	COG0521	Mo-molybdopterin cofactor biosynthetic process
LG653_13400	COG0315	cyclic pyranopterin monophosphate synthase activity
LG653_13415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LG653_13420	COG0243	molybdopterin cofactor binding
LG653_13430	COG0243	molybdopterin cofactor binding
LG653_13435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG653_13440	COG2146	nitrite reductase [NAD(P)H] activity
LG653_13440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG653_13455	COG1116	anion transmembrane transporter activity
LG653_13455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG653_13465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG653_13470	COG2423	ornithine cyclodeaminase activity
LG653_13475	COG4264	IucA IucC family
LG653_13485	COG4264	IucA IucC family
LG653_13510	COG0511	ligase activity, forming carbon-carbon bonds
LG653_13525	COG2814	Major facilitator Superfamily
LG653_13550	COG0069	glutamate synthase activity
LG653_13580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG653_13595	COG1335	isochorismatase
LG653_13610	COG1454	alcohol dehydrogenase
LG653_13615	COG0824	Thioesterase
LG653_13630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LG653_13655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG653_13660	COG2030	dehydratase
LG653_13665	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_13670	COG0183	Belongs to the thiolase family
LG653_13680	COG0583	DNA-binding transcription factor activity
LG653_13685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LG653_13695	COG1522	sequence-specific DNA binding
LG653_13700	COG3135	benzoate transporter
LG653_13720	COG0589	response to stress
LG653_13725	COG0488	(ABC) transporter
LG653_13760	COG0583	DNA-binding transcription factor activity
LG653_13780	COG2826	transposase and inactivated derivatives, IS30 family
LG653_13790	COG1733	regulation of RNA biosynthetic process
LG653_13800	COG3772	lysozyme
LG653_13850	COG4774	siderophore transport
LG653_13855	COG4772	TonB-dependent receptor
LG653_13870	COG1605	Chorismate mutase
LG653_13910	COG0308	aminopeptidase N
LG653_13935	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LG653_13960	COG0531	amino acid
LG653_13965	COG4303	Ethanolamine ammonia lyase large subunit
LG653_13970	COG4302	ethanolamine ammonia-lyase activity
LG653_13975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG653_13975	COG0519	Catalyzes the synthesis of GMP from XMP
LG653_13980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LG653_14005	COG0697	spore germination
LG653_14010	COG1923	regulation of RNA biosynthetic process
LG653_14020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LG653_14025	COG0802	atpase or kinase
LG653_14045	COG1187	pseudouridine synthase activity
LG653_14060	COG0583	DNA-binding transcription factor activity
LG653_14070	COG2814	Major facilitator Superfamily
LG653_14075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LG653_14105	COG0729	surface antigen
LG653_14125	COG2826	transposase and inactivated derivatives, IS30 family
LG653_14135	COG0174	glutamine synthetase
LG653_14140	COG0745	RESPONSE REGULATOR receiver
LG653_14145	COG2205	protein histidine kinase activity
LG653_14155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LG653_14160	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LG653_14170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LG653_14185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG653_14190	COG1960	acyl-CoA dehydrogenase activity
LG653_14205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG653_14210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG653_14215	COG2890	protein-(glutamine-N5) methyltransferase activity
LG653_14230	COG0583	DNA-binding transcription factor activity
LG653_14245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG653_14255	COG3658	cytochrome
LG653_14260	COG1215	transferase activity, transferring glycosyl groups
LG653_14265	COG0726	polysaccharide deacetylase
LG653_14265	COG1649	PFAM Uncharacterised BCR, COG1649
LG653_14295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG653_14300	COG1845	cytochrome c oxidase, subunit III
LG653_14305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LG653_14330	COG0305	Participates in initiation and elongation during chromosome replication
LG653_14335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LG653_14345	COG1305	Transglutaminase-like
LG653_14355	COG2308	Evidence 4 Homologs of previously reported genes of
LG653_14385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LG653_14395	COG0151	Belongs to the GarS family
LG653_14405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LG653_14410	COG2011	ABC-type metal ion transport system permease component
LG653_14415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG653_14425	COG1301	dicarboxylic acid transport
LG653_14455	COG1794	racemase activity, acting on amino acids and derivatives
LG653_14470	COG0745	RESPONSE REGULATOR receiver
LG653_14475	COG0642	Histidine kinase
LG653_14480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LG653_14490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LG653_14530	COG2351	hydroxyisourate hydrolase activity
LG653_14540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LG653_14540	COG3008	intermembrane lipid transfer
LG653_14545	COG2995	paraquat-inducible protein a
LG653_14560	COG2985	domain, Protein
LG653_14570	COG1309	transcriptional regulator
LG653_14605	COG2826	transposase and inactivated derivatives, IS30 family
LG653_14625	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_14630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LG653_14630	COG0475	glutathione-regulated potassium exporter activity
LG653_14635	COG0786	glutamate:sodium symporter activity
LG653_14640	COG3243	poly(R)-hydroxyalkanoic acid synthase
LG653_14655	COG1278	Cold shock
LG653_14710	COG1610	YqeY-like protein
LG653_14715	COG4783	chaperone-mediated protein folding
LG653_14740	COG1286	toxin biosynthetic process
LG653_14770	COG0778	Nitroreductase
LG653_14780	COG0513	Belongs to the DEAD box helicase family
LG653_14805	COG2363	Small membrane protein
LG653_14835	COG4650	regulator
LG653_14840	COG1234	tRNA 3'-trailer cleavage
LG653_14845	COG1690	Belongs to the RtcB family
LG653_14865	COG2195	Cleaves the N-terminal amino acid of tripeptides
LG653_14870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG653_14880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LG653_14895	COG1960	acyl-CoA dehydrogenase activity
LG653_14900	COG1301	dicarboxylic acid transport
LG653_14905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LG653_14910	COG3139	Protein of unknown function (DUF1315)
LG653_14915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LG653_14920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG653_14930	COG0494	nUDIX hydrolase
LG653_14940	COG0642	Histidine kinase
LG653_14955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LG653_14965	COG1720	tRNA m6t6A37 methyltransferase activity
LG653_14975	COG0384	phenazine biosynthesis protein PhzF
LG653_14980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG653_14985	COG0826	peptidase U32
LG653_14990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LG653_15000	COG4598	ABC transporter
LG653_15005	COG4160	amino acid transport
LG653_15010	COG4215	(ABC) transporter
LG653_15015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG653_15025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_15145	COG3561	AntA/AntB antirepressor
LG653_15395	COG0582	viral genome integration into host DNA
LG653_15400	COG1131	(ABC) transporter
LG653_15405	COG0842	Transport permease protein
LG653_15420	COG0772	Belongs to the SEDS family
LG653_15425	COG2951	lytic endotransglycosylase activity
LG653_15465	COG0052	Belongs to the universal ribosomal protein uS2 family
LG653_15470	COG0024	Methionine aminopeptidase
LG653_15480	COG2223	nitrite transmembrane transporter activity
LG653_15490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG653_15495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LG653_15500	COG1960	acyl-CoA dehydrogenase activity
LG653_15515	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LG653_15520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LG653_15525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LG653_15545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG653_15550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LG653_15555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LG653_15590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LG653_15600	COG0174	glutamine synthetase
LG653_15615	COG0582	viral genome integration into host DNA
LG653_15635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG653_15705	COG1196	nuclear chromosome segregation
LG653_15705	COG0741	lytic transglycosylase activity
LG653_15705	COG0739	heme binding
LG653_15715	COG1598	PFAM Uncharacterised protein family UPF0150
LG653_15985	COG0512	Glutamine amidotransferase of anthranilate synthase
LG653_16020	COG2840	Smr protein MutS2
LG653_16030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LG653_16040	COG0302	gtp cyclohydrolase
LG653_16060	COG3739	integral membrane protein
LG653_16075	COG1169	isochorismate synthase
LG653_16080	COG2977	Belongs to the P-Pant transferase superfamily
LG653_16085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LG653_16090	COG1132	(ABC) transporter
LG653_16095	COG1132	(ABC) transporter
LG653_16105	COG1535	isochorismatase
LG653_16105	COG3433	isochorismatase activity
LG653_16110	COG1021	2,3-dihydroxybenzoate-AMP ligase
LG653_16115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG653_16125	COG4774	siderophore transport
LG653_16130	COG4607	ABC-type enterochelin transport system periplasmic component
LG653_16135	COG4604	ABC transporter, ATP-binding protein
LG653_16140	COG4605	iron ion homeostasis
LG653_16145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG653_16150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG653_16165	COG1741	Belongs to the pirin family
LG653_16210	COG2879	small protein
LG653_16215	COG1966	Carbon starvation protein
LG653_16220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LG653_16260	COG1067	ATP-dependent peptidase activity
LG653_16265	COG0583	DNA-binding transcription factor activity
LG653_16290	COG1686	Belongs to the peptidase S11 family
LG653_16295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LG653_16330	COG0616	signal peptide processing
LG653_16335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LG653_16345	COG0573	inorganic phosphate transmembrane transporter activity
LG653_16350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LG653_16355	COG1113	amino acid transport
LG653_16360	COG3961	Belongs to the TPP enzyme family
LG653_16365	COG1522	sequence-specific DNA binding
LG653_16375	COG0076	glutamate decarboxylase activity
LG653_16380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LG653_16395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG653_16430	COG0352	thiamine-phosphate diphosphorylase activity
LG653_16465	COG0612	Peptidase, M16
LG653_16475	COG1823	symporter activity
LG653_16480	COG0583	DNA-binding transcription factor activity
LG653_16485	COG0477	Major facilitator Superfamily
LG653_16500	COG1187	pseudouridine synthase activity
LG653_16515	COG1686	Belongs to the peptidase S11 family
LG653_16520	COG1252	NADH dehydrogenase
LG653_16530	COG0415	Belongs to the DNA photolyase family
LG653_16545	COG1215	transferase activity, transferring glycosyl groups
LG653_16560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LG653_16575	COG2070	2-Nitropropane dioxygenase
LG653_16620	COG2962	Rard protein
LG653_16630	COG0556	nucleotide-excision repair
LG653_16650	COG0436	Aminotransferase
LG653_16680	COG4221	oxidoreductase activity
LG653_16690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LG653_16705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LG653_16710	COG0571	ribonuclease III activity
LG653_16720	COG0681	Belongs to the peptidase S26 family
LG653_16725	COG0481	GTPase activity
LG653_16735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG653_16755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LG653_16760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG653_16765	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LG653_16775	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LG653_16780	COG4208	sulfate ABC transporter
LG653_16785	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LG653_16790	COG0583	DNA-binding transcription factor activity
LG653_16795	COG4625	pathogenesis
LG653_16810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LG653_16825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LG653_16840	COG1051	belongs to the nudix hydrolase family
LG653_16840	COG1056	cytidyltransferase-related domain
LG653_16845	COG1024	Enoyl-CoA hydratase
LG653_16850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LG653_16855	COG2814	Major facilitator Superfamily
LG653_16860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LG653_16860	COG0047	phosphoribosylformylglycinamidine synthase activity
LG653_16880	COG1473	amidohydrolase
LG653_16885	COG0824	Thioesterase
LG653_16905	COG0823	Involved in the tonB-independent uptake of proteins
LG653_16925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG653_16960	COG0628	permease
LG653_16970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LG653_16975	COG0596	Alpha beta hydrolase
LG653_16980	COG0616	signal peptide processing
LG653_16980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LG653_16990	COG0658	competence protein
LG653_16990	COG2333	competence protein COMEC
LG653_16995	COG1136	(ABC) transporter
LG653_17000	COG4591	ABC-type transport system involved in lipoprotein release permease component
LG653_17035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_17065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LG653_17070	COG1280	lysine exporter protein (LysE YggA)
LG653_17080	COG0019	diaminopimelate decarboxylase activity
LG653_17090	COG1113	amino acid transport
LG653_17095	COG1115	amino acid carrier protein
LG653_17120	COG3339	Conserved Protein
LG653_17125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LG653_17130	COG0243	molybdopterin cofactor binding
LG653_17135	COG1929	Belongs to the glycerate kinase type-1 family
LG653_17150	COG0778	Nitroreductase
LG653_17155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG653_17160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_17200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LG653_17220	COG0741	lytic transglycosylase activity
LG653_17240	COG0584	glycerophosphoryl diester phosphodiesterase
LG653_17245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG653_17270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LG653_17275	COG1597	lipid kinase activity
LG653_17290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LG653_17295	COG0477	Major facilitator Superfamily
LG653_17305	COG2264	protein methyltransferase activity
LG653_17345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LG653_17350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LG653_17380	COG0505	Belongs to the CarA family
LG653_17400	COG0251	oxidation-reduction process
LG653_17410	COG0589	response to stress
LG653_17430	COG2843	Capsule synthesis protein
LG653_17450	COG2321	neutral zinc metallopeptidase
LG653_17455	COG2354	Protein conserved in bacteria
LG653_17475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG653_17500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LG653_17505	COG1053	succinate dehydrogenase
LG653_17510	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LG653_17515	COG2009	succinate dehydrogenase
LG653_17555	COG2921	Belongs to the UPF0250 family
LG653_17560	COG0321	lipoyl(octanoyl) transferase activity
LG653_17575	COG0531	amino acid
LG653_17610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LG653_17615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LG653_17615	COG1648	precorrin-2 dehydrogenase activity
LG653_17630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LG653_17655	COG0671	phosphoesterase, PA-phosphatase related
LG653_17660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG653_17670	COG1538	Outer membrane efflux protein
LG653_17675	COG0393	Putative heavy-metal-binding
LG653_17680	COG0393	Putative heavy-metal-binding
LG653_17690	COG1028	Short-chain dehydrogenase reductase Sdr
LG653_17700	COG0525	valine-tRNA ligase activity
LG653_17725	COG0583	DNA-binding transcription factor activity
LG653_17730	COG0004	ammonium transporteR
LG653_17745	COG0642	Histidine kinase
LG653_17750	COG0745	RESPONSE REGULATOR receiver
LG653_17755	COG2194	sulfuric ester hydrolase activity
LG653_17780	COG1752	Esterase of the alpha-beta hydrolase superfamily
LG653_17795	COG2315	Protein conserved in bacteria
LG653_17800	COG0142	geranyltranstransferase activity
LG653_17805	COG2828	Protein conserved in bacteria
LG653_17810	COG1113	amino acid transport
LG653_17820	COG3046	protein related to deoxyribodipyrimidine photolyase
LG653_17840	COG0582	viral genome integration into host DNA
LG653_17870	COG0305	Participates in initiation and elongation during chromosome replication
LG653_17925	COG3081	Nucleoid-associated protein
LG653_17975	COG2207	Transcriptional regulator
LG653_18000	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG653_18020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG653_18030	COG1530	ribonuclease E activity
LG653_18035	COG0424	maF-like protein
LG653_18040	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LG653_18045	COG1792	Involved in formation and maintenance of cell shape
LG653_18050	COG1077	Cell shape determining protein MreB Mrl
LG653_18055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LG653_18065	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LG653_18090	COG3590	peptidase
LG653_18095	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LG653_18100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LG653_18105	COG1752	Esterase of the alpha-beta hydrolase superfamily
LG653_18110	COG1115	amino acid carrier protein
LG653_18130	COG2814	Major facilitator Superfamily
LG653_18135	COG1289	transmembrane transporter activity
LG653_18145	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LG653_18185	COG1376	ErfK ybiS ycfS ynhG family protein
LG653_18190	COG2832	Protein of unknown function (DUF454)
LG653_18200	COG5510	response to toxic substance
LG653_18220	COG0840	transmembrane signaling receptor activity
LG653_18260	COG3422	double-strand break repair
LG653_18265	COG2824	Alkylphosphonate utilization operon protein PhnA
LG653_18270	COG3189	MarR family transcriptional regulator
LG653_18275	COG0596	Alpha beta hydrolase
LG653_18280	COG0778	Nitroreductase
LG653_18285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG653_18290	COG1335	isochorismatase
LG653_18295	COG0251	oxidation-reduction process
LG653_18300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG653_18305	COG2233	PERMEase
LG653_18325	COG0354	folic acid binding
LG653_18330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG653_18340	COG0679	Auxin Efflux Carrier
LG653_18345	COG1902	pentaerythritol trinitrate reductase activity
LG653_18350	COG4772	TonB-dependent receptor
LG653_18355	COG2094	Belongs to the DNA glycosylase MPG family
LG653_18380	COG1217	gtp-binding protein TYPA
LG653_18385	COG2233	PERMEase
LG653_18395	COG0833	amino acid
LG653_18400	COG1690	Belongs to the RtcB family
LG653_18405	COG2885	chlorophyll binding
LG653_18405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LG653_18415	COG0183	Belongs to the thiolase family
LG653_18435	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG653_18455	COG2207	Transcriptional regulator
LG653_18460	COG0183	Belongs to the thiolase family
LG653_18480	COG2153	protein acetylation
LG653_18490	COG1272	protein, Hemolysin III
LG653_18495	COG0477	Major facilitator Superfamily
LG653_18510	COG0450	alkyl hydroperoxide reductase
LG653_18530	COG0285	dihydrofolate synthase activity
LG653_18575	COG4206	TonB-dependent receptor
LG653_18580	COG2096	Adenosyltransferase
LG653_18600	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LG653_18610	COG0745	RESPONSE REGULATOR receiver
LG653_18615	COG2205	protein histidine kinase activity
LG653_18625	COG1960	acyl-CoA dehydrogenase activity
LG653_18630	COG1960	acyl-CoA dehydrogenase activity
LG653_18635	COG0583	DNA-binding transcription factor activity
LG653_18640	COG0625	glutathione transferase activity
LG653_18690	COG1216	Glycosyl transferase, family 2
LG653_18705	COG0726	polysaccharide deacetylase
LG653_18720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LG653_18725	COG0784	Response regulator, receiver
LG653_18725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG653_18725	COG2198	Histidine kinase
LG653_18725	COG2205	protein histidine kinase activity
LG653_18730	COG4695	Portal protein
LG653_18870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG653_18970	COG1862	Preprotein translocase
LG653_18980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG653_18985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LG653_18995	COG3781	membrane
LG653_19010	COG2350	Protein conserved in bacteria
LG653_19045	COG1607	acyl-coa hydrolase
LG653_19070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG653_19090	COG0604	alcohol dehydrogenase
LG653_19090	COG3321	synthase
LG653_19095	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LG653_19100	COG0583	DNA-binding transcription factor activity
LG653_19105	COG4221	oxidoreductase activity
LG653_19145	COG3077	Addiction module antitoxin, RelB DinJ family
LG653_19160	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LG653_19185	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LG653_19210	COG2826	transposase and inactivated derivatives, IS30 family
LG653_19275	COG2184	nucleotidyltransferase activity
LG653_19310	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
LG653_19420	COG1785	Belongs to the alkaline phosphatase family
LG653_19425	COG1475	DNA binding
LG653_19430	COG1192	Involved in chromosome partitioning
LG653_19455	COG0604	alcohol dehydrogenase
LG653_19480	COG0582	viral genome integration into host DNA
LG653_19495	COG2130	NADP-dependent
LG653_19500	COG1309	transcriptional regulator
LG653_19510	COG1902	pentaerythritol trinitrate reductase activity
LG653_19520	COG1979	alcohol dehydrogenase
LG653_19535	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LG653_19565	COG0477	Major facilitator Superfamily
LG653_19570	COG0697	spore germination
LG653_19795	COG0589	response to stress
LG653_19825	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LG653_19855	COG0659	secondary active sulfate transmembrane transporter activity
LG653_19860	COG0589	response to stress
LG653_19890	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LG653_19960	COG1401	restriction endodeoxyribonuclease activity
LG653_19980	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LG653_19995	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LG653_20005	COG3077	Addiction module antitoxin, RelB DinJ family
LG653_20065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LG653_20075	COG2026	Addiction module toxin, RelE StbE family
LG653_20100	COG1192	Involved in chromosome partitioning
LG653_20150	COG1401	restriction endodeoxyribonuclease activity
LG653_20170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LG653_20185	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LG653_20265	COG2026	Addiction module toxin, RelE StbE family
LG653_20290	COG1192	Involved in chromosome partitioning