locus-tag class description IEC338SC_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) IEC338SC_0004 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IEC338SC_0007 ENOG4105C5H ABC transporter IEC338SC_0008 ENOG4108821 RND type efflux pump IEC338SC_0009 ENOG4108821 RND type efflux pump IEC338SC_0010 ENOG4108821 RND type efflux pump IEC338SC_0012 ENOG4105D74 hydrolase IEC338SC_0013 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) IEC338SC_0014 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) IEC338SC_0022 ENOG4105C8J )-transporter IEC338SC_0024 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B IEC338SC_0030 ENOG4105C2W permease IEC338SC_0032 ENOG4108IG5 Transcriptional regulator IEC338SC_0033 ENOG4105DJY efflux transporter, rnd family, mfp subunit IEC338SC_0040 ENOG4105F27 Major Facilitator IEC338SC_0041 ENOG4105CV8 reductase IEC338SC_0042 ENOG4105HEI LysR family (Transcriptional regulator IEC338SC_0045 ENOG4105DQ4 alcohol dehydrogenase IEC338SC_0046 ENOG4108R3E Dna-3-methyladenine glycosylase i IEC338SC_0049 ENOG4105CEN a g-specific adenine glycosylase IEC338SC_0053 ENOG4108ZZ3 UPF0260 protein IEC338SC_0054 ENOG4105D8V Glucose sorbosone dehydrogenase IEC338SC_0055 ENOG4105D1H recombination factor protein RarA IEC338SC_0056 ENOG4105S64 Formate nitrite transporter IEC338SC_0060 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IEC338SC_0061 ENOG4108RWI nicotinamidase IEC338SC_0062 ENOG4105C09 Bile acid IEC338SC_0063 ENOG4105UQX Mate efflux family protein IEC338SC_0064 ENOG4105EWC Purine nucleoside phosphorylase IEC338SC_0067 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) IEC338SC_0068 ENOG4108RXX maleylacetoacetate isomerase IEC338SC_0070 ENOG4105C85 amino acid IEC338SC_0072 ENOG4105CKI cobalamin synthesis protein IEC338SC_0074 ENOG4105CZE histidine utilization repressor IEC338SC_0075 ENOG41090B9 response to stress IEC338SC_0078 ENOG4105C85 amino acid IEC338SC_0080 ENOG41088SP formiminoglutamate hydrolase IEC338SC_0082 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 IEC338SC_0083 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) IEC338SC_0084 ENOG4108NIW Leucine export protein LeuE IEC338SC_0087 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) IEC338SC_0089 ENOG4108ZAI phosphatidylglycerophosphatase a IEC338SC_0090 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) IEC338SC_0093 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) IEC338SC_0100 ENOG4105KHC sulfurtransferase IEC338SC_0106 ENOG4105BZU Histidine kinase IEC338SC_0107 ENOG4105CK6 Two component transcriptional regulator (Winged helix family IEC338SC_0110 ENOG4107QJQ Mate efflux family protein IEC338SC_0111 ENOG4105CHM Aminotransferase IEC338SC_0112 ENOG4106BRA Membrane IEC338SC_0115 ENOG4105D9M gamma-glutamylcysteine synthetase IEC338SC_0121 ENOG4105IPS esterase IEC338SC_0122 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IEC338SC_0123 ENOG4108Z2U ureidoglycolate hydrolase IEC338SC_0125 ENOG41061H0 Monooxygenase IEC338SC_0128 ENOG41084YZ Hydrolase IEC338SC_0134 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) IEC338SC_0135 ENOG4105BZU Histidine kinase IEC338SC_0138 ENOG4105KUZ arsenate reductase IEC338SC_0139 ENOG4105CGK Exodeoxyribonuclease III IEC338SC_0145 ENOG4105D7Z glutathione synthase IEC338SC_0149 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) IEC338SC_0150 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) IEC338SC_0151 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) IEC338SC_0154 ENOG41063SB peptidase IEC338SC_0155 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) IEC338SC_0156 ENOG4107QSN dihydrolipoamide acetyltransferase IEC338SC_0159 ENOG4105E0K tonB-dependent siderophore receptor IEC338SC_0161 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) IEC338SC_0164 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) IEC338SC_0166 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) IEC338SC_0168 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IEC338SC_0169 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase IEC338SC_0171 ENOG4105D64 Mechanosensitive ion channel IEC338SC_0173 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) IEC338SC_0174 ENOG4108W2Y isochorismatase IEC338SC_0176 ENOG4105FBW Monooxygenase IEC338SC_0177 ENOG4108UZX fmn reductase IEC338SC_0180 ENOG4105BZU Histidine kinase IEC338SC_0181 ENOG41062QD Membrane IEC338SC_0182 ENOG4107QN1 sodium solute IEC338SC_0184 ENOG4105C94 Transporter IEC338SC_0186 ENOG4105BZU Histidine kinase IEC338SC_0187 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) IEC338SC_0188 ENOG4108WUH Transcriptional regulator, TetR family IEC338SC_0191 ENOG4105RA2 Membrane IEC338SC_0192 ENOG4108IXY short-chain dehydrogenase reductase IEC338SC_0194 ENOG4105DWF phosphomethylpyrimidine kinase IEC338SC_0196 ENOG4107RDB Major Facilitator IEC338SC_0197 ENOG4108UUM single-stranded DNA-binding protein IEC338SC_0199 ENOG4108UMN azlc family IEC338SC_0204 ENOG4105C85 amino acid IEC338SC_0206 ENOG4108JPW Aminotransferase IEC338SC_0207 ENOG4105C26 Dehydrogenase IEC338SC_0209 ENOG4105CHJ isochorismatase hydrolase IEC338SC_0210 ENOG4105EUB pirin domain protein IEC338SC_0215 ENOG4105D94 Major Facilitator Superfamily IEC338SC_0216 ENOG4106NZI LysR family Transcriptional regulator IEC338SC_0220 ENOG4105CPC Aldo Keto reductase IEC338SC_0221 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) IEC338SC_0222 ENOG4105R8C Transcriptional regulator IEC338SC_0226 ENOG4105KVH Transcriptional regulator IEC338SC_0227 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein IEC338SC_0240 ENOG4105CUV Homoserine Kinase IEC338SC_0243 ENOG41061CK Antibiotic biosynthesis monooxygenase IEC338SC_0246 ENOG41083J0 (ABC) transporter IEC338SC_0248 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) IEC338SC_0250 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) IEC338SC_0256 ENOG4105CYC Transferase IEC338SC_0257 ENOG4105E0F Histidine kinase IEC338SC_0258 ENOG4105DPZ Two component transcriptional regulator (Winged helix family IEC338SC_0260 ENOG4105CHH sulfate transporter IEC338SC_0261 ENOG4105PDP Short chain dehydrogenase IEC338SC_0263 ENOG4105VCH membrane IEC338SC_0266 ENOG4105C5H ABC transporter IEC338SC_0282 ENOG4108IQI permease IEC338SC_0287 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein IEC338SC_0290 ENOG4105CJN penicillin-binding protein IEC338SC_0291 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) IEC338SC_0292 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) IEC338SC_0295 ENOG4105DHI Methyltransferase IEC338SC_0296 ENOG4108JQC penicillin-binding protein 1A IEC338SC_0301 ENOG4105E4G Type IV pilus IEC338SC_0305 ENOG4105CBC glutamate synthase IEC338SC_0306 ENOG4105BZ8 glutamate synthase IEC338SC_0308 ENOG4108V0P LemA family IEC338SC_0309 ENOG4105HA9 of methanol dehydrogenase type IEC338SC_0311 ENOG4105KHS type IV fimbrial pilin protein IEC338SC_0313 ENOG4108J1Q IEC338SC_0314 ENOG4108YSG O-Antigen polymerase IEC338SC_0315 ENOG4108UQY Iron-storage protein IEC338SC_0317 ENOG4105KME endoribonuclease L-psp IEC338SC_0318 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) IEC338SC_0320 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) IEC338SC_0330 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) IEC338SC_0332 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) IEC338SC_0333 ENOG4107IFA Lipase (EC 3.1.1.3) IEC338SC_0334 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) IEC338SC_0335 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) IEC338SC_0339 ENOG4107AQZ Membrane IEC338SC_0340 ENOG4108JQ1 Dehydrogenase IEC338SC_0341 ENOG4105CQB FAD linked oxidase domain protein IEC338SC_0343 ENOG4105VRH Antibiotic biosynthesis monooxygenase IEC338SC_0344 ENOG4105NF4 modulator of drug activity IEC338SC_0346 ENOG4107QF7 multi-drug IEC338SC_0347 ENOG4105EM2 membrane IEC338SC_0348 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) IEC338SC_0349 ENOG4105IPI Membrane IEC338SC_0356 ENOG4108IQI permease IEC338SC_0357 ENOG4105D82 Glutamate dehydrogenase IEC338SC_0358 ENOG4105C8Y Acetylornithine aminotransferase IEC338SC_0360 ENOG4105C26 Dehydrogenase IEC338SC_0365 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin IEC338SC_0368 ENOG4105EGI Transcriptional regulator IEC338SC_0374 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit IEC338SC_0380 ENOG41067S9 phage shock protein C, PspC IEC338SC_0382 ENOG4105CSU acyl-Coa dehydrogenase IEC338SC_0385 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) IEC338SC_0388 ENOG4105ECY inositol monophosphatase IEC338SC_0389 ENOG4105C1J atp-dependent rna helicase IEC338SC_0391 ENOG4105DHJ ABC, transporter IEC338SC_0392 ENOG4105CY3 ABC transporter, permease IEC338SC_0394 ENOG4105E3I toluene tolerance IEC338SC_0396 ENOG4105D7N magnesium and cobalt transport protein CorA IEC338SC_0397 ENOG4108URH decarboxylase IEC338SC_0399 ENOG4105MJ2 Competence protein IEC338SC_0400 ENOG4105CB5 ATP-dependent DNA helicase recG IEC338SC_0403 ENOG4105E55 glycerol-3-phosphate acyltransferase IEC338SC_0404 ENOG4105C29 acyl-CoA thioesterase IEC338SC_0405 ENOG4105CK2 sodium dicarboxylate symporter IEC338SC_0408 ENOG4105KPV Transcriptional regulator IEC338SC_0410 ENOG4105D7A ATP-binding protein IEC338SC_0411 ENOG4105C28 cystathionine IEC338SC_0412 ENOG41089BK Glutamine amido-transferase IEC338SC_0414 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) IEC338SC_0415 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) IEC338SC_0434 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) IEC338SC_0435 ENOG41067V7 50S ribosomal protein L36 IEC338SC_0437 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) IEC338SC_0442 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_0450 ENOG4105VKU nucleicacid-binding protein IEC338SC_0451 ENOG4105DGW oligopeptidase A IEC338SC_0452 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) IEC338SC_0461 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase IEC338SC_0462 ENOG4107S2Z UPF0761 membrane protein IEC338SC_0463 ENOG4105CS1 NAD(P)H quinone oxidoreductase IEC338SC_0469 ENOG4105C9A Phoh family IEC338SC_0471 ENOG4105E4C Lytic transglycosylase catalytic IEC338SC_0477 ENOG4105D6S protein involved in catabolism of external DNA IEC338SC_0478 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase IEC338SC_0487 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase IEC338SC_0489 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) IEC338SC_0490 ENOG4105DTN riboflavin biosynthesis protein ribF IEC338SC_0492 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) IEC338SC_0493 ENOG4108R86 Transcriptional regulator IEC338SC_0494 ENOG4108VM9 ABC, transporter IEC338SC_0495 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component IEC338SC_0496 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) IEC338SC_0497 ENOG4105GVF (ABC) transporter IEC338SC_0498 ENOG4105GVF (ABC) transporter IEC338SC_0499 ENOG4107QZM n-acetylglutamate synthase IEC338SC_0502 ENOG4105UBK short-chain dehydrogenase reductase IEC338SC_0503 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) IEC338SC_0506 ENOG41062JF Transcriptional regulator IEC338SC_0507 ENOG4105EJ2 Transcriptional regulator IEC338SC_0511 ENOG4105HSS phospholipase C IEC338SC_0513 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase IEC338SC_0514 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase IEC338SC_0515 ENOG4105CJR Integral membrane protein (MviN IEC338SC_0516 ENOG4108V1T peptidylprolyl cis-trans isomerase IEC338SC_0517 ENOG4108V1T peptidylprolyl cis-trans isomerase IEC338SC_0518 ENOG4105D75 Capsular exopolysaccharide family IEC338SC_0520 ENOG4105DAY polysaccharide export protein IEC338SC_0521 ENOG4107QQG Dehydrogenase IEC338SC_0522 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase IEC338SC_0523 ENOG4108IJ1 Dehydrogenase IEC338SC_0525 ENOG4105E2K Glycosyl transferase (Group 1 IEC338SC_0532 ENOG4105D3Q Sugar transferase IEC338SC_0533 ENOG4107WZ3 Transferase IEC338SC_0534 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase IEC338SC_0536 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase IEC338SC_0537 ENOG4105C6Y Udp-glucose 6-dehydrogenase IEC338SC_0539 ENOG4105CMR udp-glucose 4-epimerase IEC338SC_0540 ENOG4107QKV phosphomannomutase IEC338SC_0541 ENOG4105DAA L-lactate IEC338SC_0542 ENOG41073TP transcriptional regulator IEC338SC_0544 ENOG4105CXG d-lactate dehydrogenase IEC338SC_0545 ENOG4105CGF Aromatic amino acid aminotransferase IEC338SC_0546 ENOG4105DRR Transcriptional regulator, GntR family IEC338SC_0547 ENOG4105CR4 methylisocitrate lyase IEC338SC_0548 ENOG4105BZN citrate synthase IEC338SC_0549 ENOG4108I0Z Aconitate hydratase IEC338SC_0552 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) IEC338SC_0558 ENOG4105DQ6 Transposase IEC338SC_0562 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) IEC338SC_0565 ENOG4108IG5 Transcriptional regulator IEC338SC_0570 ENOG4105D3G Pseudouridine synthase IEC338SC_0575 ENOG4105EW9 transcriptional regulator AsnC family IEC338SC_0578 ENOG4105M4H endoribonuclease L-psp IEC338SC_0579 ENOG4105C85 amino acid IEC338SC_0580 ENOG4105C85 amino acid IEC338SC_0582 ENOG4105C26 Dehydrogenase IEC338SC_0583 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase IEC338SC_0585 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_0586 ENOG4105E39 Enoyl-CoA hydratase IEC338SC_0587 ENOG4105E39 Enoyl-CoA hydratase IEC338SC_0588 ENOG4105CSH Transporter IEC338SC_0593 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_0602 ENOG4107PSF BolA-like protein IEC338SC_0604 ENOG4107QJE Chromosome Partitioning Protein IEC338SC_0607 ENOG4105DQR SNARE associated Golgi IEC338SC_0608 ENOG4108VBZ doxx family IEC338SC_0609 ENOG4106MP8 UPF0754 membrane protein IEC338SC_0610 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) IEC338SC_0611 ENOG4108RR8 protoporphyrinogen oxidase IEC338SC_0616 ENOG4105EUB pirin domain protein IEC338SC_0621 ENOG4107R1I NAD-dependent malic enzyme IEC338SC_0622 ENOG4105EZR dyp-type peroxidase family protein IEC338SC_0624 ENOG4105FAV ABC, transporter IEC338SC_0625 ENOG4105FDK ABC transporter IEC338SC_0630 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) IEC338SC_0633 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) IEC338SC_0635 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) IEC338SC_0638 ENOG4108V06 Glutathione peroxidase IEC338SC_0642 ENOG4108IND Tetr family transcriptional regulator IEC338SC_0645 ENOG4105C79 DNA protecting protein DprA IEC338SC_0652 ENOG4105Y7M Transcriptional regulator, TetR family IEC338SC_0658 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) IEC338SC_0659 ENOG4105C6T cysteine synthase IEC338SC_0662 ENOG4105CS1 NAD(P)H quinone oxidoreductase IEC338SC_0666 ENOG4105CCT upf0313 protein IEC338SC_0670 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) IEC338SC_0672 ENOG4105C0R drug resistance transporter emrb qaca subfamily IEC338SC_0673 ENOG4108URH decarboxylase IEC338SC_0674 ENOG4105EE5 Membrane protein terC IEC338SC_0676 ENOG4105EN6 Membrane IEC338SC_0677 ENOG41079KZ Major Facilitator Superfamily IEC338SC_0678 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IEC338SC_0679 ENOG4105CEY Amp-dependent synthetase and ligase IEC338SC_0682 ENOG4105F0N pyrophosphate phospho-hydrolase IEC338SC_0683 ENOG4105EPF Outer membrane porin IEC338SC_0686 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IEC338SC_0687 ENOG4105FB2 class II Aldolase IEC338SC_0688 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IEC338SC_0690 ENOG4105C0P Mg chelatase subunit ChlI IEC338SC_0693 ENOG4105BZU Histidine kinase IEC338SC_0695 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) IEC338SC_0703 ENOG4108K5H permease YjgP YjgQ family protein IEC338SC_0704 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) IEC338SC_0705 ENOG4105CN1 protease IEC338SC_0706 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family IEC338SC_0707 ENOG4107TUY Histidine kinase IEC338SC_0709 ENOG41061WM D-Alanyl-D-Alanine IEC338SC_0711 ENOG4105D6E homoserine dehydrogenase IEC338SC_0712 ENOG4105T95 Thiol disulfide interChange protein IEC338SC_0713 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) IEC338SC_0715 ENOG4105CE1 Ferrous iron transport protein b IEC338SC_0718 ENOG4105CNI cell division protein FtsW IEC338SC_0719 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) IEC338SC_0720 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters IEC338SC_0721 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) IEC338SC_0726 ENOG4108RNG Permease of the drug metabolite transporter IEC338SC_0727 ENOG4105DFG type I secretion outer membrane protein IEC338SC_0728 ENOG4108UTW Plays a role in the regulation of phosphate uptake IEC338SC_0731 ENOG4108HRK Histidine kinase IEC338SC_0732 ENOG4108NEV two component transcriptional regulator, LytTR family IEC338SC_0733 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) IEC338SC_0738 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS IEC338SC_0741 ENOG4105GVR general secretion pathway protein D IEC338SC_0742 ENOG4105TV9 FHA Domain-Containing protein IEC338SC_0743 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) IEC338SC_0749 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) IEC338SC_0751 ENOG4105PM1 preprotein translocase subunit SecE IEC338SC_0752 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) IEC338SC_0763 ENOG4105D3Y Na H antiporter IEC338SC_0766 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) IEC338SC_0769 ENOG4107ZXU DSBA oxidoreductase IEC338SC_0771 ENOG4108Z6Z Transcriptional regulator IEC338SC_0782 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase IEC338SC_0783 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) IEC338SC_0789 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) IEC338SC_0791 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) IEC338SC_0794 ENOG4105C2N RNA methyltransferase TrmH family group 3 IEC338SC_0796 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) IEC338SC_0799 ENOG4107QHF type ii secretion system protein e IEC338SC_0801 ENOG4107EJC Preprotein translocase subunit SecG IEC338SC_0806 ENOG4105CHV Transcription elongation factor NusA IEC338SC_0808 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) IEC338SC_0809 ENOG4105KJM monovalent cation h antiporter subunit g IEC338SC_0810 ENOG4105W4C monovalent cation H antiporter subunit F IEC338SC_0811 ENOG4105SC1 monovalent cation H antiporter subunit E IEC338SC_0812 ENOG4107R4Z monovalent cation h antiporter subunit d IEC338SC_0813 ENOG4108ZE9 Monovalent cation H antiporter subunit C IEC338SC_0814 ENOG4105D65 subunit l IEC338SC_0817 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase IEC338SC_0818 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase IEC338SC_0820 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) IEC338SC_0822 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) IEC338SC_0824 ENOG4105CSR polyphosphate kinase 2 IEC338SC_0826 ENOG4105DSY exodeoxyribonuclease V, gamma IEC338SC_0827 ENOG4107QKA exodeoxyribonuclease V beta IEC338SC_0828 ENOG4107QYX exodeoxyribonuclease v alpha IEC338SC_0831 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) IEC338SC_0832 ENOG4107QUT magnesium and cobalt transport protein CorA IEC338SC_0833 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) IEC338SC_0834 ENOG4105DVC DnaJ domain protein IEC338SC_0836 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) IEC338SC_0838 ENOG4105C25 Primosomal protein n' IEC338SC_0839 ENOG4105D7Q type ii secretion system IEC338SC_0840 ENOG4108VAU general secretion pathway protein G IEC338SC_0842 ENOG4108Z7R Chaperone CsaA IEC338SC_0843 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) IEC338SC_0844 ENOG4108JU5 Magnesium and cobalt efflux protein IEC338SC_0845 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) IEC338SC_0847 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase IEC338SC_0849 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) IEC338SC_0852 ENOG4105C5X domain protein IEC338SC_0853 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) IEC338SC_0855 ENOG4105BZ8 glutamate synthase IEC338SC_0862 ENOG4107T8P acyl-Coa dehydrogenase IEC338SC_0864 ENOG4107QI1 Mate efflux family protein IEC338SC_0866 ENOG4105CSA Coproporphyrinogen iii oxidase IEC338SC_0867 ENOG4105EMU Dehydrogenase IEC338SC_0868 ENOG4105CBN LysR family transcriptional regulator IEC338SC_0872 ENOG4105C03 ribonuclease IEC338SC_0873 ENOG4105EI2 Pseudouridine synthase IEC338SC_0875 ENOG4105D29 Helix-turn-helix type 11 domain protein IEC338SC_0878 ENOG4108W5M transcriptional regulator IEC338SC_0881 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase IEC338SC_0891 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) IEC338SC_0902 ENOG4105CK2 sodium dicarboxylate symporter IEC338SC_0904 ENOG4105D1S lipid A biosynthesis IEC338SC_0906 ENOG4105C5H ABC transporter IEC338SC_0907 ENOG41069P5 Protein slyX homolog IEC338SC_0908 ENOG4105CIS alcohol dehydrogenase IEC338SC_0909 ENOG4105KVH Transcriptional regulator IEC338SC_0911 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) IEC338SC_0914 ENOG4105C4R Atp-dependent dna helicase IEC338SC_0919 ENOG4105CKD glutathione-regulated potassium-efflux system protein IEC338SC_0920 ENOG4105W0E 50S ribosomal protein L33 IEC338SC_0921 ENOG4105KDC 50s ribosomal protein l28 IEC338SC_0922 ENOG4107RGH Aldehyde dehydrogenase IEC338SC_0924 ENOG4105CIY formyltetrahydrofolate deformylase IEC338SC_0944 ENOG4105DWV Homoserine O-trans-acetylase IEC338SC_0946 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) IEC338SC_0948 ENOG4108ESX Receptor IEC338SC_0950 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) IEC338SC_0954 ENOG4107GFK fumarate IEC338SC_0955 ENOG4108DNC Involved in acetate metabolism (By similarity) IEC338SC_0956 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) IEC338SC_0957 ENOG4105C01 Dihydroxy-acid dehydratase IEC338SC_0958 ENOG4108UHU Aldolase IEC338SC_0959 ENOG4105C6Z Gluconate IEC338SC_0960 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family IEC338SC_0961 ENOG4105C26 Dehydrogenase IEC338SC_0963 ENOG4106HB6 Alpha beta hydrolase IEC338SC_0966 ENOG4105CN1 protease IEC338SC_0969 ENOG4105WVQ Fe-S assembly protein IscX IEC338SC_0973 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) IEC338SC_0977 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) IEC338SC_0981 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) IEC338SC_0985 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) IEC338SC_0987 ENOG4105C84 Histidine ammonia-lyase IEC338SC_0993 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) IEC338SC_0995 ENOG4105C2D reductase IEC338SC_0996 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) IEC338SC_1000 ENOG4105VW4 glutaredoxin 3 IEC338SC_1002 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) IEC338SC_1003 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) IEC338SC_1005 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH IEC338SC_1006 ENOG4105ENJ RND efflux system, outer membrane lipoprotein IEC338SC_1007 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) IEC338SC_1008 ENOG4105DJY efflux transporter, rnd family, mfp subunit IEC338SC_1012 ENOG4105C7K acetolactate synthase IEC338SC_1013 ENOG4108ZP8 Acetolactate synthase small subunit IEC338SC_1014 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase IEC338SC_1015 ENOG4105BZU Histidine kinase IEC338SC_1016 ENOG4108RZE Tetr family transcriptional regulator IEC338SC_1018 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) IEC338SC_1021 ENOG4105F8V Hydrolase, tatD family IEC338SC_1022 ENOG4107QM5 aconitate hydratase IEC338SC_1023 ENOG4105CUZ uba thif-type nad fad binding protein IEC338SC_1024 ENOG4107RSM transcriptional regulator IEC338SC_1027 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) IEC338SC_1030 ENOG4106UX7 integral membrane protein IEC338SC_1031 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) IEC338SC_1032 ENOG4105W8H transhydrogenase (subunit alpha IEC338SC_1033 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) IEC338SC_1037 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) IEC338SC_1038 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase IEC338SC_1039 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase IEC338SC_1040 ENOG4105BZU Histidine kinase IEC338SC_1041 ENOG4105C6T cysteine synthase IEC338SC_1044 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) IEC338SC_1049 ENOG4105EMU Dehydrogenase IEC338SC_1050 ENOG4105DXN mazG family IEC338SC_1051 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein IEC338SC_1052 ENOG4105DJ0 Poly(A) Polymerase IEC338SC_1053 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase IEC338SC_1057 ENOG41080Z8 PHOSPHOCARRIER protein IEC338SC_1058 ENOG4105N42 UPF0307 protein IEC338SC_1059 ENOG4105CEY Amp-dependent synthetase and ligase IEC338SC_1062 ENOG4105CYM Glutathione S-transferase IEC338SC_1063 ENOG4105W39 Membrane IEC338SC_1065 ENOG41082NX 50s ribosomal protein l35 IEC338SC_1066 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) IEC338SC_1069 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) IEC338SC_1072 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) IEC338SC_1074 ENOG4105C9X ppx gppa phosphatase IEC338SC_1076 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) IEC338SC_1077 ENOG4105II7 pyrroline-5-carboxylate reductase IEC338SC_1078 ENOG4108VIA integral membrane protein IEC338SC_1079 ENOG4105C2M dna polymerase I IEC338SC_1083 ENOG4107QHF type ii secretion system protein e IEC338SC_1084 ENOG4108ZHJ Organic hydroperoxide resistance protein IEC338SC_1085 ENOG4105K56 Transcriptional regulator IEC338SC_1099 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) IEC338SC_1100 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) IEC338SC_1101 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) IEC338SC_1103 ENOG4105CRQ synthase (Component I) IEC338SC_1112 ENOG4108Z0R Transferase IEC338SC_1113 ENOG41072GX Peptidase M22 Glycoprotease IEC338SC_1118 ENOG4105DJV ribulose-phosphate 3-epimerase IEC338SC_1119 ENOG4108HCJ Hydrolase IEC338SC_1121 ENOG4105E3B Multicopper oxidase IEC338SC_1125 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) IEC338SC_1126 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) IEC338SC_1127 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) IEC338SC_1132 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) IEC338SC_1134 ENOG4105ETT transcriptional Regulator, LysR family IEC338SC_1135 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_1136 ENOG4107RGD Major Facilitator superfamily IEC338SC_1137 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F IEC338SC_1142 ENOG4107EFR Flavocytochrome c IEC338SC_1143 ENOG4106P55 Transcriptional regulator IEC338SC_1146 ENOG4106P55 Transcriptional regulator IEC338SC_1152 ENOG4105ETT transcriptional Regulator, LysR family IEC338SC_1154 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) IEC338SC_1155 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) IEC338SC_1166 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) IEC338SC_1168 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) IEC338SC_1169 ENOG4107EXC regulatoR IEC338SC_1170 ENOG4105E0F Histidine kinase IEC338SC_1172 ENOG4105BZU Histidine kinase IEC338SC_1176 ENOG4105GKE subunit e IEC338SC_1177 ENOG4107QIZ NADH dehydrogenase IEC338SC_1178 ENOG4108IEH NADH dehydrogenase subunit g IEC338SC_1181 ENOG4107UFS subunit j IEC338SC_1183 ENOG4105D65 subunit l IEC338SC_1184 ENOG4105C8S subunit m IEC338SC_1188 ENOG4105DUM transcriptional regulator, lysR family IEC338SC_1189 ENOG4105DP0 ferredoxin-NADP reductase IEC338SC_1194 ENOG4105CBX hi0933 family IEC338SC_1195 ENOG4105K6H D-cysteine desulfhydrase IEC338SC_1202 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) IEC338SC_1204 ENOG4105D1F ATP-binding protein IEC338SC_1205 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) IEC338SC_1214 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) IEC338SC_1216 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY IEC338SC_1219 ENOG4105HF0 Membrane IEC338SC_1221 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) IEC338SC_1225 ENOG4106UW1 Major Facilitator superfamily IEC338SC_1226 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase IEC338SC_1227 ENOG4108K4C ec 3.1.3.12 IEC338SC_1228 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) IEC338SC_1230 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) IEC338SC_1231 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) IEC338SC_1233 ENOG4105FE9 pseudouridine synthase IEC338SC_1234 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) IEC338SC_1235 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) IEC338SC_1236 ENOG4107RTD sua5 ycio yrdc ywlc family protein IEC338SC_1237 ENOG4108BPE -transporting atpase IEC338SC_1238 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein IEC338SC_1240 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase IEC338SC_1241 ENOG4105CHR reductase IEC338SC_1243 ENOG4109066 lysm domain bon superfamily protein IEC338SC_1244 ENOG4105DWF phosphomethylpyrimidine kinase IEC338SC_1246 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) IEC338SC_1252 ENOG4105C5T Phosphoribosyl pyrophosphate synthase IEC338SC_1257 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) IEC338SC_1260 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) IEC338SC_1261 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane IEC338SC_1262 ENOG4105C34 Pseudouridine synthase IEC338SC_1263 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase IEC338SC_1267 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding IEC338SC_1270 ENOG4105EJC lysr family transcriptional regulator IEC338SC_1271 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) IEC338SC_1272 ENOG4105C94 Transporter IEC338SC_1274 ENOG4105DVW rieske (2Fe-2S) IEC338SC_1275 ENOG4105C26 Dehydrogenase IEC338SC_1276 ENOG4105E3J oxidoreductase IEC338SC_1279 ENOG4105C4K Nad synthetase IEC338SC_1281 ENOG4108YXA Membrane IEC338SC_1284 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) IEC338SC_1286 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) IEC338SC_1287 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) IEC338SC_1290 ENOG4105KEG ribosomal-protein-alanine acetyltransferase IEC338SC_1292 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) IEC338SC_1293 ENOG4105C3M thioredoxin reductase IEC338SC_1294 ENOG4105CNU cell division protein FtsK IEC338SC_1298 ENOG4107QMS site-determining protein IEC338SC_1301 ENOG4106HNH Acyl-transferase IEC338SC_1302 ENOG4108ZG0 Ompa motb domain protein IEC338SC_1303 ENOG4105C4R Atp-dependent dna helicase IEC338SC_1305 ENOG4107QKV phosphomannomutase IEC338SC_1308 ENOG4105E7A Glutamine amidotransferase IEC338SC_1311 ENOG4105VDB UPF0125 protein IEC338SC_1313 ENOG41090R7 Ferric uptake IEC338SC_1314 ENOG4105CZX twitching motility protein IEC338SC_1315 ENOG4105CZX twitching motility protein IEC338SC_1316 ENOG4105DFA alanine racemase domain protein IEC338SC_1319 ENOG4105EYH Exonuclease IEC338SC_1320 ENOG4107RH8 nuclease SbcCD subunit D IEC338SC_1324 ENOG4105ECP epimerase IEC338SC_1325 ENOG4105MWK D-amino acid dehydrogenase, small subunit IEC338SC_1326 ENOG4105D52 delta-aminolevulinic acid dehydratase IEC338SC_1327 ENOG4108VUY thioesterase Superfamily protein IEC338SC_1328 ENOG4105CW7 secretion protein, HlyD family IEC338SC_1329 ENOG4105C0R drug resistance transporter emrb qaca subfamily IEC338SC_1330 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) IEC338SC_1332 ENOG4105DFP Integrase IEC338SC_1342 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) IEC338SC_1345 ENOG4105C4R Atp-dependent dna helicase IEC338SC_1349 ENOG4105C4R Atp-dependent dna helicase IEC338SC_1359 ENOG4105DQ6 Transposase IEC338SC_1361 ENOG4105C54 Major Facilitator superfamily IEC338SC_1362 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) IEC338SC_1372 ENOG4105D5Q Arginine ornithine antiporter IEC338SC_1373 ENOG4107QK5 Homocysteine s-methyltransferase IEC338SC_1378 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) IEC338SC_1379 ENOG4105C94 Transporter IEC338SC_1380 ENOG4105C94 Transporter IEC338SC_1384 ENOG4105CKI cobalamin synthesis protein IEC338SC_1386 ENOG4108VWS Yaeq family IEC338SC_1388 ENOG4107BJW polysaccharide deacetylase IEC338SC_1389 ENOG4105CND Glycosyl transferase, family 2 IEC338SC_1391 ENOG4105E9F Enoyl-CoA hydratase IEC338SC_1394 ENOG41069M3 Transcriptional regulator IEC338SC_1398 ENOG4105CHR reductase IEC338SC_1401 ENOG4105DJB Major Facilitator Superfamily IEC338SC_1403 ENOG4108MXF Alpha Beta Hydrolase IEC338SC_1404 ENOG4105CHR reductase IEC338SC_1407 ENOG4105C7K acetolactate synthase IEC338SC_1409 ENOG4105CSH Transporter IEC338SC_1410 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) IEC338SC_1411 ENOG4105CSV Glutaminase IEC338SC_1412 ENOG4108R6W Transcriptional regulator, ARAC family IEC338SC_1413 ENOG4105EU0 Major facilitator Superfamily IEC338SC_1414 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) IEC338SC_1417 ENOG4105C3R Methionine synthase IEC338SC_1418 ENOG4105CJ3 phosphate transporter IEC338SC_1422 ENOG4105E6M Sulphatase-modifying factor protein IEC338SC_1423 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) IEC338SC_1426 ENOG4105D05 Receptor IEC338SC_1430 ENOG4108UJV acyl-CoA thioesterase i IEC338SC_1431 ENOG4108I0Y (ABC) transporter IEC338SC_1432 ENOG4105CV6 ABC transporter, permease IEC338SC_1433 ENOG4107U91 Rhomboid family IEC338SC_1437 ENOG4105C5Q Transcriptional regulator IEC338SC_1438 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) IEC338SC_1439 ENOG4107QZF nitrite reductase NADPH large subunit IEC338SC_1440 ENOG4105VCQ rubredoxin IEC338SC_1444 ENOG4108MRJ IEC338SC_1447 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) IEC338SC_1450 ENOG4105D4T Citrate transporter IEC338SC_1451 ENOG4105C37 (CBS) domain IEC338SC_1453 ENOG4107RET Isocitrate lyase IEC338SC_1454 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion IEC338SC_1459 ENOG4105CQM Urea amidohydrolase subunit alpha IEC338SC_1461 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) IEC338SC_1465 ENOG4106H78 methyltransferase IEC338SC_1466 ENOG4105CJN penicillin-binding protein IEC338SC_1472 ENOG4105KKX ATPase associated with various cellular activities aaa_5 IEC338SC_1473 ENOG4105RD5 IEC338SC_1474 ENOG4105DEG Vwa containing coxe family protein IEC338SC_1475 ENOG4105CSM endonuclease III IEC338SC_1476 ENOG4108R3D Electron transport complex IEC338SC_1477 ENOG4105D82 Glutamate dehydrogenase IEC338SC_1479 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b IEC338SC_1482 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase IEC338SC_1488 ENOG4107RAQ aminopeptidase IEC338SC_1489 ENOG4105D0A hydroxylase IEC338SC_1490 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family IEC338SC_1492 ENOG4105W1Y Transcriptional regulator IEC338SC_1494 ENOG4108ZUB Lysine exporter protein (Lyse ygga) IEC338SC_1497 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) IEC338SC_1499 ENOG4105W4M Transport-associated protein IEC338SC_1501 ENOG4105E09 nadh pyrophosphatase IEC338SC_1503 ENOG4108JDX DNA polymerase iii, epsilon subunit IEC338SC_1504 ENOG4105E9H Lytic Murein transglycosylase IEC338SC_1505 ENOG4105E43 Extracellular solute-binding protein, family 5 IEC338SC_1506 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component IEC338SC_1507 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component IEC338SC_1508 ENOG4108JQ5 ABC transporter IEC338SC_1512 ENOG4108KU3 Integrase IEC338SC_1528 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) IEC338SC_1533 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IEC338SC_1535 ENOG4105U5Y Transcriptional regulator IEC338SC_1537 ENOG4105M4H endoribonuclease L-psp IEC338SC_1538 ENOG4105MWK D-amino acid dehydrogenase, small subunit IEC338SC_1539 ENOG4105CR8 Transcriptional regulator IEC338SC_1544 ENOG4108M3P Membrane IEC338SC_1548 ENOG4105CS6 Rhs element vgr protein IEC338SC_1555 ENOG4105C85 amino acid IEC338SC_1557 ENOG4105CUB amino acid IEC338SC_1561 ENOG4105C26 Dehydrogenase IEC338SC_1565 ENOG4105C85 amino acid IEC338SC_1566 ENOG4105D5K Hemolysin activator protein IEC338SC_1567 ENOG4105CKT filamentous hemagglutinin IEC338SC_1571 ENOG4107RGH Aldehyde dehydrogenase IEC338SC_1575 ENOG4105DJP Membrane IEC338SC_1578 ENOG4105NI3 Protein of unknown function (DUF3237) IEC338SC_1579 ENOG4105EPF Outer membrane porin IEC338SC_1580 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_1583 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase IEC338SC_1584 ENOG4108SC4 )-transporter IEC338SC_1587 ENOG4105E3J oxidoreductase IEC338SC_1590 ENOG4105E6M Sulphatase-modifying factor protein IEC338SC_1591 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) IEC338SC_1592 ENOG4105D2S major facilitator superfamily IEC338SC_1593 ENOG4105EPF Outer membrane porin IEC338SC_1594 ENOG4105DDY UPF0142 protein ycaO IEC338SC_1598 ENOG4107RN6 Monooxygenase IEC338SC_1600 ENOG4107GFK fumarate IEC338SC_1601 ENOG4106DSS Tartrate dehydratase subunit alpha IEC338SC_1603 ENOG4105EJC lysr family transcriptional regulator IEC338SC_1604 ENOG4105JQZ Methyltransferase IEC338SC_1605 ENOG4105F95 Monooxygenase IEC338SC_1611 ENOG4105C7N Xanthine uracil vitamin C permease IEC338SC_1612 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) IEC338SC_1613 ENOG4105CPW cytochrome b561 IEC338SC_1615 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) IEC338SC_1617 ENOG4105CFH Aspartokinase IEC338SC_1619 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase IEC338SC_1621 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis IEC338SC_1624 ENOG4105CPC Aldo Keto reductase IEC338SC_1625 ENOG4107RYR Transcriptional regulator, Crp Fnr family IEC338SC_1626 ENOG4108UKZ OsmC family IEC338SC_1629 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit IEC338SC_1635 ENOG4105CD3 dihydroorotase IEC338SC_1636 ENOG4108ZG0 Ompa motb domain protein IEC338SC_1638 ENOG4108TGY Glutathione S-transferase IEC338SC_1640 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) IEC338SC_1642 ENOG4108K3A Glutathione S-transferase IEC338SC_1644 ENOG4108JU3 Alkyl hydroperoxide reductase IEC338SC_1648 ENOG4105D3R alkyl hydroperoxide reductase IEC338SC_1649 ENOG4105CQ7 ATP-dependent helicase IEC338SC_1652 ENOG4105D2S major facilitator superfamily IEC338SC_1653 ENOG4105DKK Benzoate IEC338SC_1654 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase IEC338SC_1655 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein IEC338SC_1656 ENOG4108UKV benzoate 1,2-dioxygenase IEC338SC_1657 ENOG4105FUY alpha subunit IEC338SC_1658 ENOG4108KB2 LysR family Transcriptional regulator IEC338SC_1660 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein IEC338SC_1664 ENOG4105EUV Phenol 2-monooxygenase IEC338SC_1676 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) IEC338SC_1683 ENOG410829K Lysine exporter protein (Lyse ygga) IEC338SC_1684 ENOG4105D1S lipid A biosynthesis IEC338SC_1685 ENOG4105VEQ Cold shock protein IEC338SC_1687 ENOG4105II7 pyrroline-5-carboxylate reductase IEC338SC_1689 ENOG4105EW9 transcriptional regulator AsnC family IEC338SC_1690 ENOG4105F2W methyltransferase IEC338SC_1692 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) IEC338SC_1695 ENOG4105DQ6 Transposase IEC338SC_1697 ENOG4105R8C Transcriptional regulator IEC338SC_1705 ENOG4105CUY Mechanosensitive ion channel IEC338SC_1708 ENOG4107YPT transcriptional regulator IEC338SC_1714 ENOG4105N82 Endonuclease IEC338SC_1719 ENOG4105C2X Arabinose 5-phosphate isomerase IEC338SC_1720 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase IEC338SC_1722 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA IEC338SC_1723 ENOG4108IUZ ABC transporter IEC338SC_1724 ENOG4105DFG type I secretion outer membrane protein IEC338SC_1726 ENOG4105C42 Type I secretion membrane fusion protein (HlyD IEC338SC_1730 ENOG4107ZBN O-methyltransferase IEC338SC_1732 ENOG4108Z4U Ferredoxin IEC338SC_1736 ENOG4108ZX5 transcriptional regulator IEC338SC_1738 ENOG4105CRN Aminoglycoside phosphotransferase IEC338SC_1739 ENOG4105D5Q Arginine ornithine antiporter IEC338SC_1743 ENOG4105CF7 AraC family transcriptional regulator IEC338SC_1745 ENOG4105DQ6 Transposase IEC338SC_1749 ENOG4105KVH Transcriptional regulator IEC338SC_1750 ENOG4107VGR Catalase IEC338SC_1751 ENOG4105CPW cytochrome b561 IEC338SC_1756 ENOG4105CBN LysR family transcriptional regulator IEC338SC_1757 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) IEC338SC_1761 ENOG4105BZU Histidine kinase IEC338SC_1765 ENOG4108IND Tetr family transcriptional regulator IEC338SC_1783 ENOG4105E18 UPF0276 protein IEC338SC_1785 ENOG4108WQI RNA Polymerase IEC338SC_1787 ENOG4108WAV Transcriptional regulator IEC338SC_1788 ENOG4105C5A transporter IEC338SC_1792 ENOG4108JIK carboxylase IEC338SC_1793 ENOG4107R4J Chloride channel IEC338SC_1794 ENOG4105D5K Hemolysin activator protein IEC338SC_1795 ENOG4105CKT filamentous hemagglutinin IEC338SC_1798 ENOG4105DQ6 Transposase IEC338SC_1803 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) IEC338SC_1804 ENOG4105E2A Dehydrogenase IEC338SC_1807 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase IEC338SC_1808 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF IEC338SC_1812 ENOG4105MRR Transcriptional regulator (By similarity) IEC338SC_1814 ENOG4108HW3 (ABC) transporter IEC338SC_1821 ENOG4105CNA YD repeat protein IEC338SC_1828 ENOG4105E6M Sulphatase-modifying factor protein IEC338SC_1839 ENOG4105EIY sodium-type flagellar protein motY IEC338SC_1841 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit IEC338SC_1849 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IEC338SC_1850 ENOG4105WPN DNA integration recombination invertion protein IEC338SC_1852 ENOG4108Z4X TRANSCRIPTIONal IEC338SC_1855 ENOG4105EJQ L-serine dehydratase IEC338SC_1856 ENOG4105DXM phenylacetic acid degradation protein IEC338SC_1857 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit IEC338SC_1858 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit IEC338SC_1859 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit IEC338SC_1860 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit IEC338SC_1861 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) IEC338SC_1862 ENOG4105E39 Enoyl-CoA hydratase IEC338SC_1863 ENOG4108UKI Enoyl-CoA hydratase IEC338SC_1864 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase IEC338SC_1865 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_1866 ENOG4105DZS Phenylacetate-CoA ligase IEC338SC_1867 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein IEC338SC_1868 ENOG4108Z0R Transferase IEC338SC_1874 ENOG4108TGR phosphatase IEC338SC_1880 ENOG4105HEI LysR family (Transcriptional regulator IEC338SC_1882 ENOG4107HP6 Transcriptional regulator IEC338SC_1883 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase IEC338SC_1885 ENOG4108NIW Leucine export protein LeuE IEC338SC_1887 ENOG4105C4Y ABC transporter IEC338SC_1888 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) IEC338SC_1889 ENOG4107RCV ABC transporter, permease IEC338SC_1891 ENOG4107STF Involved in phosphonate degradation (By similarity) IEC338SC_1892 ENOG4108KAZ Involved in phosphonate degradation (By similarity) IEC338SC_1893 ENOG4107RGD Major Facilitator superfamily IEC338SC_1894 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_1897 ENOG4108UKI Enoyl-CoA hydratase IEC338SC_1898 ENOG4105EA8 2-Nitropropane dioxygenase IEC338SC_1899 ENOG4105EQ0 Major Facilitator superfamily IEC338SC_1901 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_1902 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase IEC338SC_1903 ENOG4105CHR reductase IEC338SC_1904 ENOG4105E39 Enoyl-CoA hydratase IEC338SC_1905 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_1906 ENOG4107RGD Major Facilitator superfamily IEC338SC_1907 ENOG4107QP7 CoA-transferase subunit A IEC338SC_1908 ENOG4107QNJ CoA-transferase subunit B IEC338SC_1910 ENOG4105EQ0 Major Facilitator superfamily IEC338SC_1912 ENOG4105CSU acyl-Coa dehydrogenase IEC338SC_1915 ENOG4105CC0 LysR family Transcriptional regulator IEC338SC_1918 ENOG4105E39 Enoyl-CoA hydratase IEC338SC_1919 ENOG4107QX3 carboxylase IEC338SC_1920 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_1921 ENOG4105R8C Transcriptional regulator IEC338SC_1922 ENOG4105CEY Amp-dependent synthetase and ligase IEC338SC_1925 ENOG4105D2S major facilitator superfamily IEC338SC_1927 ENOG4105HEI LysR family (Transcriptional regulator IEC338SC_1937 ENOG4105CYX Short-chain dehydrogenase reductase Sdr IEC338SC_1941 ENOG4105KT5 UmuD protein IEC338SC_1943 ENOG4105EW9 transcriptional regulator AsnC family IEC338SC_1945 ENOG4105BZU Histidine kinase IEC338SC_1946 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase IEC338SC_1948 ENOG4105EAD ABC transporter IEC338SC_1949 ENOG4108HW4 amino acid AbC transporter IEC338SC_1951 ENOG4107RP9 extracellular solute-binding protein, family 3 IEC338SC_1952 ENOG4105CT1 (ABC) transporter IEC338SC_1953 ENOG4105EXG Transcriptional regulator IEC338SC_1955 ENOG4105C9B Cysteine desulfurase IEC338SC_1956 ENOG4105ESN nucleotide-binding protein IEC338SC_1957 ENOG4105D7W serine acetyltransferase IEC338SC_1959 ENOG4105CHR reductase IEC338SC_1960 ENOG4105CBN LysR family transcriptional regulator IEC338SC_1961 ENOG4105CYM Glutathione S-transferase IEC338SC_1962 ENOG4108SHQ Glutathione S-transferase IEC338SC_1963 ENOG4105CMU LysR family (Transcriptional regulator IEC338SC_1964 ENOG4105VAW lrga family IEC338SC_1965 ENOG41067MG lrgb family IEC338SC_1969 ENOG4105DXI Major Facilitator superfamily IEC338SC_1971 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase IEC338SC_1972 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) IEC338SC_1975 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase IEC338SC_1979 ENOG4108K70 Transcriptional regulator IEC338SC_1980 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IEC338SC_1982 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii IEC338SC_1983 ENOG4105C4M (Ubiquinol oxidase) subunit I IEC338SC_1987 ENOG4105C54 Major Facilitator superfamily IEC338SC_1989 ENOG4106FTQ Taurine ABC transporter, periplasmic IEC338SC_1990 ENOG4108IY8 ABC, transporter IEC338SC_1991 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component IEC338SC_1992 ENOG4105E2B Taurine dioxygenase IEC338SC_1994 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease IEC338SC_1996 ENOG4105CBN LysR family transcriptional regulator IEC338SC_1999 ENOG4105CPN adenine deaminase IEC338SC_2002 ENOG41082YX Transcriptional regulator, arsr family IEC338SC_2004 ENOG4105D6J arsenicaL-resistance protein IEC338SC_2005 ENOG4105CAU Arsenical resistance protein, ArsH IEC338SC_2006 ENOG4108KB2 LysR family Transcriptional regulator IEC338SC_2009 ENOG4108JU3 Alkyl hydroperoxide reductase IEC338SC_2014 ENOG4105C0B DNA polymerase III (alpha subunit) IEC338SC_2016 ENOG4105CK2 sodium dicarboxylate symporter IEC338SC_2017 ENOG4105CHM Aminotransferase IEC338SC_2019 ENOG4108V06 Glutathione peroxidase IEC338SC_2020 ENOG4105E7U AraC family transcriptional regulator IEC338SC_2026 ENOG4105ZED uncharacterized protein ygaH IEC338SC_2027 ENOG4108UMN azlc family IEC338SC_2032 ENOG4105C3G gtp-binding protein IEC338SC_2033 ENOG4108UMI ABC transporter, permease IEC338SC_2034 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) IEC338SC_2035 ENOG4105D01 (LipO)protein IEC338SC_2036 ENOG4105D01 (LipO)protein IEC338SC_2039 ENOG4107T8P acyl-Coa dehydrogenase IEC338SC_2042 ENOG4105EAD ABC transporter IEC338SC_2043 ENOG4105DRP amino acid AbC transporter IEC338SC_2044 ENOG4105CDA abc transporter atp-binding protein IEC338SC_2046 ENOG4105EW9 transcriptional regulator AsnC family IEC338SC_2049 ENOG41067SE Tetr family transcriptional regulator IEC338SC_2052 ENOG4105HEI LysR family (Transcriptional regulator IEC338SC_2054 ENOG4105ETS cytosine purines uracil thiamine allantoin IEC338SC_2056 ENOG4108IPJ Membrane IEC338SC_2057 ENOG4108R4R Iron-regulated virulence regulatory protein IEC338SC_2060 ENOG4105GQR Chaperone IEC338SC_2061 ENOG4105X0I Fimbrial IEC338SC_2065 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) IEC338SC_2066 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) IEC338SC_2070 ENOG4108HWY Beta-lactamase IEC338SC_2075 ENOG4105CV1 Transketolase (EC 2.2.1.1) IEC338SC_2077 ENOG4108YYC ycei family IEC338SC_2079 ENOG4108T58 Mg2 transport protein CorA IEC338SC_2082 ENOG4105YGK Pfam:UPF0157 IEC338SC_2083 ENOG4105C26 Dehydrogenase IEC338SC_2084 ENOG4105EW9 transcriptional regulator AsnC family IEC338SC_2085 ENOG4105CK7 Sodium proline symporter IEC338SC_2086 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) IEC338SC_2088 ENOG4108ZX5 transcriptional regulator IEC338SC_2090 ENOG4105BZ1 (ABC) transporter IEC338SC_2092 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme IEC338SC_2093 ENOG4105XPP Protein of unknown function (DUF1275) IEC338SC_2095 ENOG41080HT Transcriptional regulator, arsr family IEC338SC_2097 ENOG4105EZE Cupin 4 family protein IEC338SC_2098 ENOG4108UHJ MAF-like protein IEC338SC_2102 ENOG4105D2N Aldolase IEC338SC_2103 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) IEC338SC_2104 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) IEC338SC_2105 ENOG4105EHM Aminoglycoside phosphotransferase IEC338SC_2106 ENOG4108S0S Nucleotidyl transferase IEC338SC_2108 ENOG4107QJE Chromosome Partitioning Protein IEC338SC_2109 ENOG4105FA0 parb-like partition protein IEC338SC_2112 ENOG4105BZ1 (ABC) transporter IEC338SC_2113 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) IEC338SC_2115 ENOG4107QRG dna polymerase iii IEC338SC_2117 ENOG4105F8V Hydrolase, tatD family IEC338SC_2122 ENOG4108RTD type II secretion system protein K IEC338SC_2126 ENOG4108Z6B deaminase IEC338SC_2129 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) IEC338SC_2130 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) IEC338SC_2133 ENOG4105DWU Membrane IEC338SC_2134 ENOG4107RN6 Monooxygenase IEC338SC_2136 ENOG4105D6Z AFG1 family ATPase IEC338SC_2137 ENOG4107QP3 malate synthase g IEC338SC_2138 ENOG4105SG9 biopolymer transport protein, ExbD IEC338SC_2142 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) IEC338SC_2144 ENOG4107QSI ABC, transporter IEC338SC_2145 ENOG4105DGW oligopeptidase A IEC338SC_2151 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase IEC338SC_2154 ENOG4105K4T epimerase IEC338SC_2155 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) IEC338SC_2159 ENOG4108JA2 transcriptioN-repair coupling factor IEC338SC_2161 ENOG4105F8J Adenylate Guanylate cyclase IEC338SC_2162 ENOG4108ZIT Ferredoxin, 2FE-2S IEC338SC_2165 ENOG4108Z4V iron-sulfur cluster assembly IEC338SC_2166 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins IEC338SC_2168 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family IEC338SC_2171 ENOG4105K70 DNA-binding protein IEC338SC_2172 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) IEC338SC_2173 ENOG4105E7U AraC family transcriptional regulator IEC338SC_2174 ENOG4105EEF Alkane 1-monooxygenase IEC338SC_2175 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_2176 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_2179 ENOG4108Z66 YbaK ebsC protein IEC338SC_2180 ENOG4107VXZ Hydrolase IEC338SC_2182 ENOG4108YZT Adenosylcobinamide kinase IEC338SC_2183 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) IEC338SC_2187 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) IEC338SC_2188 ENOG4107TSN permease IEC338SC_2191 ENOG4105CNM Receptor IEC338SC_2192 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) IEC338SC_2197 ENOG4105K59 histidine triad (HIT) protein IEC338SC_2201 ENOG4105C28 cystathionine IEC338SC_2204 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) IEC338SC_2206 ENOG4107U5X Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) IEC338SC_2215 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) IEC338SC_2216 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) IEC338SC_2219 ENOG4105BZU Histidine kinase IEC338SC_2222 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) IEC338SC_2223 ENOG4107R0V Pyruvate dehydrogenase IEC338SC_2224 ENOG4105CPP Dehydrogenase, E1 component IEC338SC_2227 ENOG4105CHR reductase IEC338SC_2229 ENOG4105FFC UPF0187 protein IEC338SC_2231 ENOG4107QPB Beta-lactamase domain protein IEC338SC_2233 ENOG4108VCT Sulfite exporter TauE/SafE IEC338SC_2236 ENOG4105UEI Transcriptional Regulator AraC Family IEC338SC_2238 ENOG4105CSH Transporter IEC338SC_2240 ENOG4108IJ0 Aspartate ammonia-lyase IEC338SC_2243 ENOG4107YNJ LysR family Transcriptional regulator IEC338SC_2245 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_2246 ENOG4105CRW Short chain fatty acid transporter IEC338SC_2249 ENOG4108M0I Transcriptional regulator IEC338SC_2260 ENOG4105CY2 Citrate transporter IEC338SC_2261 ENOG4105DTD Dehydrogenase IEC338SC_2262 ENOG4105CF7 AraC family transcriptional regulator IEC338SC_2263 ENOG4105D2S major facilitator superfamily IEC338SC_2266 ENOG4105CHR reductase IEC338SC_2271 ENOG4105F57 Anthranilate dioxygenase reductase IEC338SC_2272 ENOG4108YS2 small subunit IEC338SC_2273 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit IEC338SC_2274 ENOG4105F4R Transcriptional regulator mode IEC338SC_2275 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein IEC338SC_2276 ENOG4105E0C molybdate abc transporter IEC338SC_2277 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) IEC338SC_2278 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase IEC338SC_2279 ENOG4105WQI isochorismatase IEC338SC_2281 ENOG4107T31 5'-nucleotidase IEC338SC_2282 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) IEC338SC_2283 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) IEC338SC_2285 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E IEC338SC_2286 ENOG4108IGT Dipeptidase IEC338SC_2289 ENOG4105BZS acriflavin resistance protein IEC338SC_2290 ENOG4105C1P efflux transporter, rnd family, mfp subunit IEC338SC_2291 ENOG4105CK6 Two component transcriptional regulator (Winged helix family IEC338SC_2292 ENOG4105E0F Histidine kinase IEC338SC_2294 ENOG4107RZC phospholipase d IEC338SC_2307 ENOG4105X0I Fimbrial IEC338SC_2314 ENOG4105CBN LysR family transcriptional regulator IEC338SC_2315 ENOG4107SYB Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) IEC338SC_2317 ENOG4105T16 Transcriptional regulator (AraC family) IEC338SC_2320 ENOG4105C4M (Ubiquinol oxidase) subunit I IEC338SC_2321 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii IEC338SC_2323 ENOG4105ECQ AraC Family Transcriptional Regulator IEC338SC_2324 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein IEC338SC_2325 ENOG4105DXI Major Facilitator superfamily IEC338SC_2327 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein IEC338SC_2329 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IEC338SC_2330 ENOG4105K63 Thioredoxin IEC338SC_2331 ENOG4105CHR reductase IEC338SC_2336 ENOG4105DC8 reductase IEC338SC_2341 ENOG4107258 Transcriptional regulator IEC338SC_2342 ENOG4105ID8 Transcriptional regulator, ARAC family IEC338SC_2344 ENOG4105WQI isochorismatase IEC338SC_2345 ENOG4105VYA Uncharacterized conserved protein (DUF2132) IEC338SC_2352 ENOG4105CKT filamentous hemagglutinin IEC338SC_2357 ENOG4105DQ6 Transposase IEC338SC_2374 ENOG4105C5T Phosphoribosyl pyrophosphate synthase IEC338SC_2378 ENOG4105E0A ABC, transporter IEC338SC_2379 ENOG4105EHG Permease protein IEC338SC_2388 ENOG4105C26 Dehydrogenase IEC338SC_2389 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) IEC338SC_2390 ENOG4105EVZ LysR family transcriptional regulator IEC338SC_2393 ENOG4105JSC dimethylmenaquinone methyltransferase IEC338SC_2394 ENOG4108JQ1 Dehydrogenase IEC338SC_2399 ENOG4106KR7 LysR family Transcriptional regulator IEC338SC_2411 ENOG4105J7D transcriptional regulator IEC338SC_2413 ENOG4105CEY Amp-dependent synthetase and ligase IEC338SC_2415 ENOG4105CSU acyl-Coa dehydrogenase IEC338SC_2417 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr IEC338SC_2418 ENOG41061TZ Short-chain dehydrogenase reductase Sdr IEC338SC_2419 ENOG41061TZ Short-chain dehydrogenase reductase Sdr IEC338SC_2420 ENOG4108PTX LysR family Transcriptional regulator IEC338SC_2421 ENOG4107Z3H Transcriptional regulator, TetR family IEC338SC_2425 ENOG4108Z6Z Transcriptional regulator IEC338SC_2427 ENOG4105NAE bifunctional deaminase-reductase domain protein IEC338SC_2429 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IEC338SC_2433 ENOG4108W5M transcriptional regulator IEC338SC_2434 ENOG4105CZM Major Facilitator IEC338SC_2435 ENOG4108SC4 )-transporter IEC338SC_2436 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase IEC338SC_2437 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) IEC338SC_2438 ENOG4108QJ2 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase IEC338SC_2440 ENOG4108SBK dioxygenase, subunit beta IEC338SC_2441 ENOG4105FUY alpha subunit IEC338SC_2442 ENOG4108W5M transcriptional regulator IEC338SC_2444 ENOG4105EPF Outer membrane porin IEC338SC_2445 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) IEC338SC_2446 ENOG4105DIV Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity) IEC338SC_2447 ENOG4105IKQ hydratase IEC338SC_2449 ENOG4108KB2 LysR family Transcriptional regulator IEC338SC_2450 ENOG4105DTQ mandelate racemase muconate lactonizing IEC338SC_2451 ENOG4105NN7 muconolactone delta-isomerase IEC338SC_2453 ENOG4107QP7 CoA-transferase subunit A IEC338SC_2454 ENOG4107QNJ CoA-transferase subunit B IEC338SC_2455 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_2456 ENOG4105F2Z 3-oxoadipate enol-lactonase IEC338SC_2457 ENOG4105C26 Dehydrogenase IEC338SC_2459 ENOG4105F11 amine oxidase IEC338SC_2463 ENOG4105CHR reductase IEC338SC_2465 ENOG4105FUY alpha subunit IEC338SC_2469 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) IEC338SC_2471 ENOG4105DNH Major Facilitator IEC338SC_2476 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_2477 ENOG4108PTX LysR family Transcriptional regulator IEC338SC_2478 ENOG4107HP6 Transcriptional regulator IEC338SC_2481 ENOG4105MD1 YeeE YedE family protein IEC338SC_2483 ENOG4105DZG Dehydrogenase IEC338SC_2484 ENOG4105TW1 Carbohydrate-selective porin OprB IEC338SC_2485 ENOG4106JPM 3-dehydroshikimate dehydratase IEC338SC_2486 ENOG4105FF2 Type I DHQase IEC338SC_2487 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha IEC338SC_2488 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta IEC338SC_2489 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase IEC338SC_2490 ENOG4105D2S major facilitator superfamily IEC338SC_2491 ENOG4105F2Z 3-oxoadipate enol-lactonase IEC338SC_2492 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase IEC338SC_2493 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_2494 ENOG4107QNJ CoA-transferase subunit B IEC338SC_2495 ENOG4107QP7 CoA-transferase subunit A IEC338SC_2497 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) IEC338SC_2498 ENOG4105CNM Receptor IEC338SC_2500 ENOG4107VMU Membrane IEC338SC_2501 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) IEC338SC_2510 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IEC338SC_2513 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) IEC338SC_2515 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit IEC338SC_2516 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) IEC338SC_2522 ENOG4105C7B Threonine dehydratase IEC338SC_2524 ENOG4105CZN Potassium uptake protein IEC338SC_2525 ENOG4105HDD phospholipase IEC338SC_2529 ENOG4105PV3 Inner membrane protein yqiJ IEC338SC_2531 ENOG4105C4M (Ubiquinol oxidase) subunit I IEC338SC_2532 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii IEC338SC_2538 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) IEC338SC_2543 ENOG4105C2X Arabinose 5-phosphate isomerase IEC338SC_2544 ENOG4105C8Y Acetylornithine aminotransferase IEC338SC_2545 ENOG4105M2J Glutaredoxin IEC338SC_2547 ENOG4105CC0 LysR family Transcriptional regulator IEC338SC_2548 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) IEC338SC_2549 ENOG4105CWM branched-chain amino acid transport system II carrier protein IEC338SC_2554 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) IEC338SC_2555 ENOG4105DE4 1-phosphofructokinase IEC338SC_2556 ENOG4105DM4 PTS System IEC338SC_2559 ENOG4105BZU Histidine kinase IEC338SC_2561 ENOG4105D8V Glucose sorbosone dehydrogenase IEC338SC_2563 ENOG4105CHH sulfate transporter IEC338SC_2567 ENOG4105C85 amino acid IEC338SC_2569 ENOG4105F7P transcriptional regulator AsnC family IEC338SC_2572 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 IEC338SC_2573 ENOG4105VEJ Heat shock protein IEC338SC_2575 ENOG4105Y3E Modulates RecA activity (By similarity) IEC338SC_2577 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) IEC338SC_2581 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane IEC338SC_2582 ENOG4105DZP Membrane-associated zinc metalloprotease IEC338SC_2584 ENOG4105KNE Phosphatidate cytidylyltransferase IEC338SC_2585 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) IEC338SC_2589 ENOG4105CUX Signal transduction histidine kinase IEC338SC_2590 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family IEC338SC_2600 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) IEC338SC_2603 ENOG4105CMR udp-glucose 4-epimerase IEC338SC_2608 ENOG4105T38 integral membrane protein IEC338SC_2609 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IEC338SC_2611 ENOG4105CVM Molybdenum cofactor synthesis domain protein IEC338SC_2612 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) IEC338SC_2616 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) IEC338SC_2619 ENOG4108IFG nitrite reductase, (NAD(P)H) IEC338SC_2620 ENOG4107QZF nitrite reductase NADPH large subunit IEC338SC_2627 ENOG4105JSC dimethylmenaquinone methyltransferase IEC338SC_2629 ENOG4105DJU Siderophore biosynthesis protein IEC338SC_2630 ENOG4105DUU IucA IucC family protein IEC338SC_2631 ENOG4105C0R drug resistance transporter emrb qaca subfamily IEC338SC_2637 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein IEC338SC_2638 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase IEC338SC_2640 ENOG4105D8G Major Facilitator superfamily IEC338SC_2645 ENOG4105NVB glycoside hydrolase, family 19 IEC338SC_2656 ENOG4105UPP uncharacterized protein ydcA IEC338SC_2667 ENOG41090AG Bacteriophage protein IEC338SC_2670 ENOG4107ZQ5 Phage-associated protein, HI1409 family IEC338SC_2701 ENOG4108D1K outer membrane usher protein IEC338SC_2704 ENOG4105CBC glutamate synthase IEC338SC_2713 ENOG4108RWI nicotinamidase IEC338SC_2716 ENOG4105C0A alcohol dehydrogenase IEC338SC_2718 ENOG4105HSS phospholipase C IEC338SC_2719 ENOG4107QMP dna polymerase iii subunits gamma and tau IEC338SC_2726 ENOG4105CHR reductase IEC338SC_2727 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_2729 ENOG4105CC0 LysR family Transcriptional regulator IEC338SC_2730 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) IEC338SC_2731 ENOG4108NIW Leucine export protein LeuE IEC338SC_2732 ENOG4105EW9 transcriptional regulator AsnC family IEC338SC_2733 ENOG4105DKK Benzoate IEC338SC_2737 ENOG41081QV Universal stress protein IEC338SC_2738 ENOG4105C5H ABC transporter IEC338SC_2739 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium IEC338SC_2749 ENOG4105KVH Transcriptional regulator IEC338SC_2751 ENOG4105KUS lysozyme IEC338SC_2758 ENOG41089BK Glutamine amido-transferase IEC338SC_2760 ENOG4105GAV receptor IEC338SC_2761 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) IEC338SC_2766 ENOG4108D1K outer membrane usher protein IEC338SC_2769 ENOG4105CD8 aminopeptidase N IEC338SC_2774 ENOG4107QUV Domain protein IEC338SC_2775 ENOG4105C0A alcohol dehydrogenase IEC338SC_2777 ENOG4107RR1 TRANSCRIPTIONal IEC338SC_2779 ENOG4107R55 ethanolamine transporter IEC338SC_2780 ENOG4105CPD ethanolamine ammonia-lyase IEC338SC_2781 ENOG4107FQ9 ethanolamine ammonia-lyase IEC338SC_2782 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) IEC338SC_2783 ENOG4105CX6 glutaminyL-tRNA synthetase IEC338SC_2787 ENOG4108RCM Nitroreductase IEC338SC_2788 ENOG4108TZV Membrane IEC338SC_2789 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) IEC338SC_2791 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) IEC338SC_2792 ENOG4105K8N protein family UPF0079, ATPase IEC338SC_2796 ENOG4105I08 Pseudouridine synthase IEC338SC_2799 ENOG4105DZ2 Transcriptional regulator IEC338SC_2801 ENOG4105F27 Major Facilitator IEC338SC_2802 ENOG4105EYW Ion transport protein IEC338SC_2804 ENOG4107QPK )-transporter IEC338SC_2806 ENOG4107QIJ Aconitate hydratase 2 IEC338SC_2811 ENOG4105CFU surface antigen IEC338SC_2812 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) IEC338SC_2815 ENOG4105CFQ glutamine synthetase IEC338SC_2816 ENOG4105EEX Two component transcriptional regulator (Winged helix family IEC338SC_2817 ENOG4105C08 Histidine kinase IEC338SC_2819 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) IEC338SC_2820 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) IEC338SC_2823 ENOG4105KRF dihydroneopterin aldolase IEC338SC_2826 ENOG4108MEJ flavin reductase domain protein IEC338SC_2827 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_2830 ENOG4105GVF (ABC) transporter IEC338SC_2831 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component IEC338SC_2832 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) IEC338SC_2835 ENOG4105CC0 LysR family Transcriptional regulator IEC338SC_2838 ENOG4105DEN Luciferase family IEC338SC_2840 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD IEC338SC_2841 ENOG4105CND Glycosyl transferase, family 2 IEC338SC_2842 ENOG4107BJW polysaccharide deacetylase IEC338SC_2847 ENOG4105E2S oxidase) subunit II IEC338SC_2848 ENOG4105BZ9 Cytochrome C oxidase, subunit I IEC338SC_2849 ENOG4105CCU oxidase (Subunit III) IEC338SC_2850 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) IEC338SC_2855 ENOG4105CDU Replicative dna helicase IEC338SC_2856 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) IEC338SC_2866 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) IEC338SC_2868 ENOG4105C12 Phosphoribosylglycinamide synthetase IEC338SC_2870 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) IEC338SC_2871 ENOG4108UMI ABC transporter, permease IEC338SC_2872 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) IEC338SC_2874 ENOG4105CK2 sodium dicarboxylate symporter IEC338SC_2883 ENOG4105ETX regulatoR IEC338SC_2884 ENOG4105DHQ Histidine kinase IEC338SC_2885 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase IEC338SC_2887 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase IEC338SC_2895 ENOG4105VT2 5-hydroxyisourate hydrolase IEC338SC_2897 ENOG4105DY2 Paraquat-inducible protein b IEC338SC_2898 ENOG4105F1S paraquat-inducible protein a IEC338SC_2900 ENOG4107NQ8 LysR family Transcriptional regulator IEC338SC_2901 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase IEC338SC_2906 ENOG4105CKD glutathione-regulated potassium-efflux system protein IEC338SC_2907 ENOG4105D6U Sodium Glutamate Symporter IEC338SC_2911 ENOG4105VEQ Cold shock protein IEC338SC_2916 ENOG4105D9P serine threonine protein kinase IEC338SC_2921 ENOG4105VCC 30S ribosomal protein S21 IEC338SC_2922 ENOG4105KTH gatB Yqey IEC338SC_2923 ENOG4105ERG peptidase m48, ste24p IEC338SC_2924 ENOG4105C5I Dehydrogenase IEC338SC_2927 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase IEC338SC_2934 ENOG41069NU Nitroreductase IEC338SC_2936 ENOG4105C1J atp-dependent rna helicase IEC338SC_2937 ENOG4105VEQ Cold shock protein IEC338SC_2939 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) IEC338SC_2940 ENOG4105M08 Membrane IEC338SC_2945 ENOG4105CYB regulatoR IEC338SC_2946 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) IEC338SC_2947 ENOG4105E0Y RtcB Protein IEC338SC_2951 ENOG4105CIN aminoacyl-histidine dipeptidase IEC338SC_2953 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase IEC338SC_2954 ENOG4105CQC Prephenate dehydratase IEC338SC_2957 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_2958 ENOG4105CK2 sodium dicarboxylate symporter IEC338SC_2959 ENOG4107QYG anthranilate phosphoribosyltransferase IEC338SC_2960 ENOG4105VUT cytoplasmic protein IEC338SC_2961 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) IEC338SC_2962 ENOG4105BZ4 penicillin-binding protein IEC338SC_2964 ENOG4105M6F mutator MutT protein IEC338SC_2966 ENOG4105DHQ Histidine kinase IEC338SC_2967 ENOG4105XJC Two component transcriptional regulator (Winged helix family IEC338SC_2969 ENOG4107QHF type ii secretion system protein e IEC338SC_2971 ENOG4108R96 Methyltransferase, YaeB family IEC338SC_2972 ENOG4105DP0 ferredoxin-NADP reductase IEC338SC_2973 ENOG4105JAB phenazine biosynthesis protein, phzf family IEC338SC_2974 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family IEC338SC_2975 ENOG4105CFP Peptidase U32 IEC338SC_2976 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding IEC338SC_2978 ENOG4108JEH abc transporter atp-binding protein IEC338SC_2979 ENOG4106YG3 ABC transporter IEC338SC_2980 ENOG4105DSP amino acid AbC transporter IEC338SC_2981 ENOG4105E89 ABC transporter IEC338SC_2983 ENOG4105ENT Efflux transporter rnd family, mfp subunit IEC338SC_2985 ENOG4105ENJ RND efflux system, outer membrane lipoprotein IEC338SC_2991 ENOG4105DA5 (ABC) transporter IEC338SC_2992 ENOG4105E3A (ABC) transporter IEC338SC_2995 ENOG4105CNI cell division protein FtsW IEC338SC_2996 ENOG4105CVE Lytic murein transglycosylase IEC338SC_3004 ENOG4105CE9 30S ribosomal protein S2 IEC338SC_3005 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) IEC338SC_3007 ENOG4107RNU major facilitator superfamily MFS_1 IEC338SC_3010 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) IEC338SC_3011 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) IEC338SC_3012 ENOG4107QPN acyl-Coa dehydrogenase IEC338SC_3015 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) IEC338SC_3016 ENOG4105SYT Methylenetetrahydrofolate reductase IEC338SC_3017 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) IEC338SC_3018 ENOG4105BZU Histidine kinase IEC338SC_3019 ENOG4105C6K Malic enzyme IEC338SC_3021 ENOG4105C0H protease IEC338SC_3022 ENOG4107QNR UPF0135 protein IEC338SC_3023 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) IEC338SC_3030 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) IEC338SC_3032 ENOG4105C5F glutamine synthetase IEC338SC_3033 ENOG4105DUX Transporter IEC338SC_3035 ENOG4105DFP Integrase IEC338SC_3055 ENOG4105XB7 anti-repressor protein IEC338SC_3087 ENOG4105CDU Replicative dna helicase IEC338SC_3092 ENOG4108XTP Transcriptional regulator IEC338SC_3099 ENOG41076J9 exonuclease VIII IEC338SC_3105 ENOG4105DDQ anthranilate synthase IEC338SC_3108 ENOG4108DG9 Smr protein MutS2 IEC338SC_3110 ENOG4105C7W Xanthine dehydrogenase IEC338SC_3112 ENOG4105EUJ GTP cyclohydrolase i IEC338SC_3113 ENOG41066YJ Beta-lactamase IEC338SC_3116 ENOG4105NX3 Membrane IEC338SC_3119 ENOG4105E4F Isochorismate synthase IEC338SC_3126 ENOG4105WQI isochorismatase IEC338SC_3127 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase IEC338SC_3128 ENOG4105C0W non-ribosomal peptide synthetase IEC338SC_3132 ENOG4108IPW abc transporter atp-binding protein IEC338SC_3136 ENOG4105CEY Amp-dependent synthetase and ligase IEC338SC_3139 ENOG4105C2I pirin domain protein IEC338SC_3140 ENOG4105WWK YheO domain protein IEC338SC_3145 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 IEC338SC_3147 ENOG4105VCD cytoplasmic protein IEC338SC_3148 ENOG4105D22 carbon starvation protein IEC338SC_3149 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) IEC338SC_3150 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein IEC338SC_3154 ENOG4105DHU Bile acid IEC338SC_3157 ENOG4105DAN ATP-dependent protease IEC338SC_3158 ENOG4105EJC lysr family transcriptional regulator IEC338SC_3159 ENOG4108K5P (LipO)protein IEC338SC_3163 ENOG4105DZ1 carboxypeptidase IEC338SC_3164 ENOG4108Z0R Transferase IEC338SC_3168 ENOG4107QTF adenylosuccinate lyase IEC338SC_3171 ENOG4105ERU peptidase IEC338SC_3172 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) IEC338SC_3174 ENOG4105C8U phosphate abc transporter IEC338SC_3175 ENOG4105CVA phosphate IEC338SC_3176 ENOG4105C85 amino acid IEC338SC_3177 ENOG4107RA9 decarboxylase IEC338SC_3178 ENOG4105F7P transcriptional regulator AsnC family IEC338SC_3180 ENOG4105DY8 decarboxylase IEC338SC_3181 ENOG4108JPW Aminotransferase IEC338SC_3184 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) IEC338SC_3187 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) IEC338SC_3188 ENOG4105D3G Pseudouridine synthase IEC338SC_3191 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) IEC338SC_3197 ENOG4105JAB phenazine biosynthesis protein, phzf family IEC338SC_3198 ENOG4108ETY sodium dicarboxylate symporter IEC338SC_3199 ENOG4105EGI Transcriptional regulator IEC338SC_3200 ENOG4105CBP Major Facilitator IEC338SC_3203 ENOG4108R99 pseudouridine synthase IEC338SC_3204 ENOG4105E9K Isocitrate dehydrogenase IEC338SC_3206 ENOG4105DZ1 carboxypeptidase IEC338SC_3207 ENOG4105CEP NADH dehydrogenase IEC338SC_3208 ENOG4108YZY peptidylprolyl cis-trans isomerase IEC338SC_3209 ENOG4105CVP deoxyribo-dipyrimidine photolyase IEC338SC_3212 ENOG4107R8N Glycosyl transferase, family 2 IEC338SC_3218 ENOG4105EA8 2-Nitropropane dioxygenase IEC338SC_3219 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) IEC338SC_3281 ENOG4107QS8 (LipO)protein IEC338SC_3288 ENOG4105DTR rard protein IEC338SC_3290 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) IEC338SC_3292 ENOG4105BZU Histidine kinase IEC338SC_3299 ENOG4105EMU Dehydrogenase IEC338SC_3300 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase IEC338SC_3301 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) IEC338SC_3302 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) IEC338SC_3304 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) IEC338SC_3305 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) IEC338SC_3307 ENOG4105C3F Signal peptidase i IEC338SC_3308 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) IEC338SC_3310 ENOG4105C0H protease IEC338SC_3311 ENOG4108IYU L-aspartate oxidase IEC338SC_3314 ENOG4105HHA aminodeoxychorismate lyase IEC338SC_3315 ENOG4105YAZ 4-amino-4-deoxychorismate lyase IEC338SC_3316 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein IEC338SC_3318 ENOG4108I5D sulfate abc transporter IEC338SC_3320 ENOG4108IJ6 ABC transporter IEC338SC_3321 ENOG4107R11 Transcriptional regulator IEC338SC_3324 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) IEC338SC_3325 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) IEC338SC_3328 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen IEC338SC_3332 ENOG4108UKI Enoyl-CoA hydratase IEC338SC_3333 ENOG4105EGD dinuclear metal center protein, YbgI family IEC338SC_3335 ENOG4105C2C drug resistance transporter, Bcr CflA IEC338SC_3337 ENOG4108ETH Formylglycinamide ribotide synthetase IEC338SC_3341 ENOG4105CH2 amidohydrolase IEC338SC_3342 ENOG4107YD3 Thioesterase IEC338SC_3343 ENOG4105E02 MotA TolQ exbB proton channel IEC338SC_3344 ENOG4105M8F Biopolymer transport protein exbD tolR IEC338SC_3346 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) IEC338SC_3347 ENOG4105KCK Peptidoglycan-associated lipoprotein IEC338SC_3357 ENOG4105C02 permease IEC338SC_3359 ENOG4108V3E phosphoribosylglycinamide formyltransferase IEC338SC_3360 ENOG4107R6F Alpha Beta Hydrolase Fold protein IEC338SC_3361 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) IEC338SC_3363 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 IEC338SC_3364 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) IEC338SC_3365 ENOG4105D60 lipoprotein releasing system transmembrane protein IEC338SC_3366 ENOG4108594 Permease of the drug metabolite transporter IEC338SC_3371 ENOG4107KET secretion protein, HlyD family IEC338SC_3374 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) IEC338SC_3375 ENOG4105C10 Electron transfer flavoprotein IEC338SC_3376 ENOG4105BZJ Electron transfer flavoprotein IEC338SC_3377 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) IEC338SC_3378 ENOG4105N14 lysine exporter protein LysE YggA IEC338SC_3382 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) IEC338SC_3384 ENOG4105C85 amino acid IEC338SC_3385 ENOG4105BZG amino acid carrier protein IEC338SC_3386 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) IEC338SC_3388 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) IEC338SC_3391 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) IEC338SC_3392 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit IEC338SC_3393 ENOG4105BZW Glycerate kinase IEC338SC_3399 ENOG4108TGR phosphatase IEC338SC_3406 ENOG4108Z6Z Transcriptional regulator IEC338SC_3411 ENOG4105D01 (LipO)protein IEC338SC_3413 ENOG4108RRZ Transcription elongation factor GreB IEC338SC_3417 ENOG4105E4C Lytic transglycosylase catalytic IEC338SC_3420 ENOG4105BZS acriflavin resistance protein IEC338SC_3421 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase IEC338SC_3423 ENOG41080IJ Diacylglycerol kinase IEC338SC_3427 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) IEC338SC_3430 ENOG4105C6V Glycerol-3-phosphate dehydrogenase IEC338SC_3431 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) IEC338SC_3432 ENOG4105CSH Transporter IEC338SC_3434 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) IEC338SC_3442 ENOG4105EEI dihydropteroate synthase IEC338SC_3443 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) IEC338SC_3445 ENOG4105HBR Rna-binding protein IEC338SC_3448 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain IEC338SC_3449 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain IEC338SC_3451 ENOG4108Q5F Tetr family transcriptional regulator IEC338SC_3452 ENOG4108UQ8 endoribonuclease L-psp IEC338SC_3455 ENOG41080TK Universal stress protein IEC338SC_3459 ENOG4105PNM synthesis protein IEC338SC_3461 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 IEC338SC_3462 ENOG4105E33 succinate dehydrogenase IEC338SC_3464 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein IEC338SC_3465 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit IEC338SC_3472 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) IEC338SC_3473 ENOG41084BA UPF0250 protein IEC338SC_3474 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) IEC338SC_3477 ENOG4105CUB amino acid IEC338SC_3480 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) IEC338SC_3481 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) IEC338SC_3484 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) IEC338SC_3489 ENOG410841Q phosphoesterase PA-phosphatase related protein IEC338SC_3490 ENOG4105C1P efflux transporter, rnd family, mfp subunit IEC338SC_3491 ENOG4105BZS acriflavin resistance protein IEC338SC_3492 ENOG4105ENJ RND efflux system, outer membrane lipoprotein IEC338SC_3493 ENOG4105K8R UPF0145 protein IEC338SC_3494 ENOG4105K8R UPF0145 protein IEC338SC_3498 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) IEC338SC_3503 ENOG4108M0I Transcriptional regulator IEC338SC_3506 ENOG4105DHQ Histidine kinase IEC338SC_3507 ENOG4105XJC Two component transcriptional regulator (Winged helix family IEC338SC_3508 ENOG4105DIJ Phosphoethanolamine transferase IEC338SC_3513 ENOG4105D78 K07001 NTE family protein IEC338SC_3516 ENOG4105MSB protein, conserved in bacteria IEC338SC_3517 ENOG4105CTB Polyprenyl synthetase IEC338SC_3518 ENOG4105C7F AcnD-accessory protein PrpF IEC338SC_3519 ENOG4105C85 amino acid IEC338SC_3520 ENOG4105E09 nadh pyrophosphatase IEC338SC_3521 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein IEC338SC_3532 ENOG4105CF7 AraC family transcriptional regulator IEC338SC_3537 ENOG4108X0B nad(p)h dehydrogenase (quinone) IEC338SC_3539 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein IEC338SC_3541 ENOG4105D8T Acyltransferase IEC338SC_3543 ENOG4105C03 ribonuclease IEC338SC_3544 ENOG4108Z03 MAF-like protein IEC338SC_3545 ENOG4105VQ7 Rod shape-determining protein MreD IEC338SC_3546 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) IEC338SC_3547 ENOG4105DFF Rod shape-determining protein mreb IEC338SC_3548 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) IEC338SC_3550 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) IEC338SC_3557 ENOG4105C7B Threonine dehydratase IEC338SC_3558 ENOG4105D78 K07001 NTE family protein IEC338SC_3559 ENOG4105BZG amino acid carrier protein IEC338SC_3562 ENOG4105C2C drug resistance transporter, Bcr CflA IEC338SC_3563 ENOG4105EM2 membrane IEC338SC_3565 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) IEC338SC_3573 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein IEC338SC_3574 ENOG4105WD1 Membrane IEC338SC_3576 ENOG4106HKS Entericidin EcnA/B family IEC338SC_3580 ENOG4105CBS Chea signal transduction histidine kinase IEC338SC_3581 ENOG4105C8Q Methyl-accepting chemotaxis IEC338SC_3582 ENOG4108ZGA chew protein IEC338SC_3583 ENOG4105M3Z response regulator IEC338SC_3584 ENOG4108UNF response regulator IEC338SC_3589 ENOG4105KWI UPF0339 protein IEC338SC_3590 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA IEC338SC_3591 ENOG4105K78 MarR family Transcriptional regulator IEC338SC_3593 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) IEC338SC_3594 ENOG4105T95 Thiol disulfide interChange protein IEC338SC_3596 ENOG4108N2Y auxin Efflux IEC338SC_3597 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase IEC338SC_3598 ENOG4105CHB tonB-dependent Receptor IEC338SC_3599 ENOG4108VX5 3-methyladenine DNA glycosylase IEC338SC_3601 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) IEC338SC_3602 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) IEC338SC_3606 ENOG4105C2W permease IEC338SC_3608 ENOG4108IQI permease IEC338SC_3609 ENOG4105E0Y RtcB Protein IEC338SC_3611 ENOG4108WHA ompa motb domain protein IEC338SC_3612 ENOG4105X0D Fimbrial protein IEC338SC_3613 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_3617 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) IEC338SC_3618 ENOG4105DZG Dehydrogenase IEC338SC_3619 ENOG4105TW1 Carbohydrate-selective porin OprB IEC338SC_3621 ENOG4108R6W Transcriptional regulator, ARAC family IEC338SC_3622 ENOG4105CHU acetyl-coa acetyltransferase IEC338SC_3626 ENOG41082BV acetyltransferase IEC338SC_3628 ENOG4108UT2 hemolysin iii IEC338SC_3629 ENOG4105CSH Transporter IEC338SC_3632 ENOG4105D3R alkyl hydroperoxide reductase IEC338SC_3636 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase IEC338SC_3643 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) IEC338SC_3646 ENOG4108WBT adenosyltransferase IEC338SC_3650 ENOG4105CNG UPF0061 protein IEC338SC_3652 ENOG4105E3W Two component transcriptional regulator (Winged helix family IEC338SC_3653 ENOG4105EB3 Histidine kinase IEC338SC_3655 ENOG4105CSU acyl-Coa dehydrogenase IEC338SC_3656 ENOG4105CSU acyl-Coa dehydrogenase IEC338SC_3657 ENOG4105EQ2 LysR family Transcriptional regulator IEC338SC_3658 ENOG4108K3A Glutathione S-transferase IEC338SC_3663 ENOG4105UGU tonB-dependent Receptor IEC338SC_3668 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) IEC338SC_3670 ENOG4108PQP glycosyl transferase group 1 IEC338SC_3671 ENOG4106WTF Glycosyl transferase, family 2 IEC338SC_3672 ENOG4107BJW polysaccharide deacetylase IEC338SC_3675 ENOG4105CM2 brancheD-chain amino acid aminotransferase IEC338SC_3676 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) IEC338SC_3677 ENOG4105BZU Histidine kinase IEC338SC_3687 ENOG4105VIE preprotein translocase, subunit YajC IEC338SC_3688 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) IEC338SC_3689 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) IEC338SC_3690 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase IEC338SC_3692 ENOG4105FFC UPF0187 protein IEC338SC_3695 ENOG4105K9H YciI-like protein IEC338SC_3702 ENOG4105NAU thioesterase Superfamily protein IEC338SC_3704 ENOG4107U2T alpha beta IEC338SC_3705 ENOG4107QPB Beta-lactamase domain protein IEC338SC_3714 ENOG4108WS1 IEC338SC_3715 ENOG4108KHX Diguanylate cyclase IEC338SC_3718 ENOG4107RZC phospholipase d IEC338SC_3720 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) IEC338SC_3724 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) IEC338SC_3725 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) IEC338SC_3726 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) IEC338SC_3727 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) IEC338SC_3728 ENOG4108UJD 30S ribosomal protein S9 IEC338SC_3729 ENOG4107MKT Stringent starvation protein a IEC338SC_3730 ENOG4105KB2 stringent starvation protein b IEC338SC_3734 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_3735 ENOG4107QX3 carboxylase IEC338SC_3738 ENOG4108RZE Tetr family transcriptional regulator IEC338SC_3739 ENOG4105C1G acyl-Coa dehydrogenase IEC338SC_3747 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) IEC338SC_3760 ENOG4105CVE Lytic murein transglycosylase IEC338SC_3761 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit IEC338SC_3762 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) IEC338SC_3765 ENOG4105DFU Cell wall formation (By similarity) IEC338SC_3767 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase IEC338SC_3768 ENOG4105DU1 integral membrane protein, terc IEC338SC_3770 ENOG4106032 Glutathionylspermidine synthase IEC338SC_3772 ENOG4107QUY Guanine deaminase IEC338SC_3774 ENOG4108UGV hypoxanthine phosphoribosyltransferase IEC338SC_3776 ENOG4105T95 Thiol disulfide interChange protein IEC338SC_3777 ENOG4105PGM cation diffusion facilitator family transporter IEC338SC_3780 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins IEC338SC_3783 ENOG4105VG0 50S ribosomal protein l34 IEC338SC_p3802 ENOG4108HWY Beta-lactamase IEC338SC_p3803 ENOG4105D9U N-acetyltransferase IEC338SC_p3804 ENOG4105XMH SpoVT AbrB domain protein