locus-tag	class	description
IEC338SC_0002	COG0592	DNA-directed DNA polymerase activity
IEC338SC_0004	COG0187	DNA topoisomerase II activity
IEC338SC_0007	COG0488	(ABC) transporter
IEC338SC_0012	COG0596	Alpha beta hydrolase
IEC338SC_0013	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IEC338SC_0014	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEC338SC_0020	COG0625	glutathione transferase activity
IEC338SC_0022	COG0733	neurotransmitter:sodium symporter activity
IEC338SC_0030	COG2233	PERMEase
IEC338SC_0033	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_0040	COG2814	Major facilitator Superfamily
IEC338SC_0041	COG0656	L-ascorbic acid biosynthetic process
IEC338SC_0042	COG0583	DNA-binding transcription factor activity
IEC338SC_0044	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_0045	COG1064	alcohol dehydrogenase
IEC338SC_0046	COG2818	Glycosylase
IEC338SC_0049	COG1194	a g-specific adenine glycosylase
IEC338SC_0052	COG5487	UPF0391 membrane protein
IEC338SC_0053	COG2983	Belongs to the UPF0260 family
IEC338SC_0054	COG2133	pyrroloquinoline quinone binding
IEC338SC_0055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IEC338SC_0056	COG2116	formate transmembrane transporter activity
IEC338SC_0060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEC338SC_0061	COG1335	isochorismatase
IEC338SC_0062	COG0385	Bile acid
IEC338SC_0063	COG0534	Mate efflux family protein
IEC338SC_0064	COG1683	Conserved Protein
IEC338SC_0067	COG0346	lactoylglutathione lyase activity
IEC338SC_0068	COG0625	glutathione transferase activity
IEC338SC_0070	COG1113	amino acid transport
IEC338SC_0072	COG0523	cobalamin synthesis protein
IEC338SC_0074	COG2188	Transcriptional regulator
IEC338SC_0080	COG0010	Belongs to the arginase family
IEC338SC_0082	COG0546	phosphoglycolate phosphatase activity
IEC338SC_0083	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IEC338SC_0084	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_0087	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IEC338SC_0089	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IEC338SC_0090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IEC338SC_0110	COG0534	Mate efflux family protein
IEC338SC_0111	COG0436	Aminotransferase
IEC338SC_0112	COG2733	membrane
IEC338SC_0115	COG2918	glutathione biosynthetic process
IEC338SC_0121	COG3150	esterase
IEC338SC_0123	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IEC338SC_0125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_0127	COG2233	PERMEase
IEC338SC_0128	COG2351	hydroxyisourate hydrolase activity
IEC338SC_0135	COG3706	GGDEF domain
IEC338SC_0138	COG1393	Belongs to the ArsC family
IEC338SC_0139	COG0708	Exodeoxyribonuclease III
IEC338SC_0145	COG0189	ligase activity
IEC338SC_0149	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IEC338SC_0151	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEC338SC_0154	COG4942	peptidase
IEC338SC_0156	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEC338SC_0158	COG2119	membrane
IEC338SC_0160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_0160	COG0426	domain, Protein
IEC338SC_0164	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IEC338SC_0168	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_0169	COG1519	Transferase
IEC338SC_0170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IEC338SC_0171	COG0668	transmembrane transport
IEC338SC_0173	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEC338SC_0174	COG1335	isochorismatase
IEC338SC_0175	COG1522	sequence-specific DNA binding
IEC338SC_0180	COG0784	Response regulator, receiver
IEC338SC_0180	COG2205	protein histidine kinase activity
IEC338SC_0180	COG2198	Histidine kinase
IEC338SC_0181	COG3162	membrane
IEC338SC_0182	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEC338SC_0184	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEC338SC_0186	COG3706	GGDEF domain
IEC338SC_0188	COG1309	transcriptional regulator
IEC338SC_0192	COG0300	oxidoreductase activity
IEC338SC_0194	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IEC338SC_0194	COG0351	phosphomethylpyrimidine kinase
IEC338SC_0194	COG0352	thiamine-phosphate diphosphorylase activity
IEC338SC_0196	COG2814	Major facilitator Superfamily
IEC338SC_0199	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IEC338SC_0204	COG1113	amino acid transport
IEC338SC_0206	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_0207	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_0209	COG1335	isochorismatase
IEC338SC_0215	COG2814	Major facilitator Superfamily
IEC338SC_0216	COG0583	DNA-binding transcription factor activity
IEC338SC_0220	COG0667	Aldo Keto reductase
IEC338SC_0222	COG1309	transcriptional regulator
IEC338SC_0226	COG1733	regulation of RNA biosynthetic process
IEC338SC_0227	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_0240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEC338SC_0243	COG2329	Antibiotic biosynthesis monooxygenase
IEC338SC_0246	COG4619	ABC transporter
IEC338SC_0248	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IEC338SC_0250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEC338SC_0256	COG0427	acetyl-CoA hydrolase
IEC338SC_0257	COG2205	protein histidine kinase activity
IEC338SC_0258	COG0745	RESPONSE REGULATOR receiver
IEC338SC_0260	COG0659	secondary active sulfate transmembrane transporter activity
IEC338SC_0261	COG4221	oxidoreductase activity
IEC338SC_0263	COG2814	Major facilitator Superfamily
IEC338SC_0266	COG0488	(ABC) transporter
IEC338SC_0282	COG0833	amino acid
IEC338SC_0291	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEC338SC_0292	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IEC338SC_0295	COG2226	methyltransferase
IEC338SC_0305	COG0067	glutamate synthase
IEC338SC_0305	COG0070	glutamate synthase
IEC338SC_0305	COG0069	glutamate synthase activity
IEC338SC_0306	COG0493	'glutamate synthase
IEC338SC_0308	COG1704	LemA family
IEC338SC_0309	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IEC338SC_0311	COG4969	Belongs to the N-Me-Phe pilin family
IEC338SC_0313	COG2801	Transposase and inactivated derivatives
IEC338SC_0314	COG3307	-O-antigen
IEC338SC_0318	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEC338SC_0320	COG0194	GDP metabolic process
IEC338SC_0330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEC338SC_0332	COG0335	large ribosomal subunit rRNA binding
IEC338SC_0334	COG5380	lipid catabolic process
IEC338SC_0335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEC338SC_0339	COG5006	permease, DMT superfamily
IEC338SC_0340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IEC338SC_0341	COG0277	FAD linked oxidase domain protein
IEC338SC_0343	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IEC338SC_0344	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_0347	COG1289	transmembrane transporter activity
IEC338SC_0349	COG0628	permease
IEC338SC_0356	COG0833	amino acid
IEC338SC_0357	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEC338SC_0358	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEC338SC_0360	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_0368	COG0583	DNA-binding transcription factor activity
IEC338SC_0374	COG0752	glycyl-tRNA synthetase alpha subunit
IEC338SC_0379	COG4109	DRTGG domain
IEC338SC_0380	COG1983	PspC domain protein
IEC338SC_0382	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_0385	COG0408	coproporphyrinogen oxidase activity
IEC338SC_0389	COG0513	Belongs to the DEAD box helicase family
IEC338SC_0391	COG1127	ABC transporter
IEC338SC_0392	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IEC338SC_0394	COG2854	intermembrane phospholipid transfer
IEC338SC_0396	COG0598	Magnesium transport protein CorA
IEC338SC_0398	COG0494	nUDIX hydrolase
IEC338SC_0399	COG1040	competence protein
IEC338SC_0400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEC338SC_0403	COG2937	Belongs to the GPAT DAPAT family
IEC338SC_0404	COG1946	Acyl-CoA thioesterase
IEC338SC_0405	COG1301	dicarboxylic acid transport
IEC338SC_0408	COG1959	2 iron, 2 sulfur cluster binding
IEC338SC_0409	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_0409	COG1017	nitric oxide dioxygenase activity
IEC338SC_0410	COG0433	COG0433 Predicted ATPase
IEC338SC_0411	COG0626	cystathionine gamma-synthase activity
IEC338SC_0414	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEC338SC_0415	COG0088	Forms part of the polypeptide exit tunnel
IEC338SC_0435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IEC338SC_0437	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEC338SC_0442	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_0443	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IEC338SC_0450	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IEC338SC_0451	COG0339	signal peptide processing
IEC338SC_0452	COG0557	exoribonuclease II activity
IEC338SC_0461	COG0179	Fumarylacetoacetate (FAA) hydrolase
IEC338SC_0462	COG1295	ribonuclease BN
IEC338SC_0469	COG1702	phosphate starvation-inducible protein PhoH
IEC338SC_0471	COG0739	heme binding
IEC338SC_0471	COG1196	nuclear chromosome segregation
IEC338SC_0471	COG0741	lytic transglycosylase activity
IEC338SC_0477	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IEC338SC_0478	COG1183	phosphatidylcholine synthase activity
IEC338SC_0487	COG1047	Peptidyl-prolyl cis-trans
IEC338SC_0489	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEC338SC_0490	COG0196	riboflavin kinase activity
IEC338SC_0492	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEC338SC_0493	COG1309	transcriptional regulator
IEC338SC_0494	COG1116	anion transmembrane transporter activity
IEC338SC_0495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEC338SC_0496	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEC338SC_0497	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_0498	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_0499	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IEC338SC_0499	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IEC338SC_0502	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_0503	COG0546	phosphoglycolate phosphatase activity
IEC338SC_0514	COG3023	N-Acetylmuramoyl-L-alanine amidase
IEC338SC_0515	COG0728	peptidoglycan biosynthetic process
IEC338SC_0520	COG1596	polysaccharide export
IEC338SC_0521	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IEC338SC_0522	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IEC338SC_0523	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IEC338SC_0525	COG0438	transferase activity, transferring glycosyl groups
IEC338SC_0529	COG1063	alcohol dehydrogenase
IEC338SC_0532	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IEC338SC_0534	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEC338SC_0536	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IEC338SC_0539	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEC338SC_0540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEC338SC_0541	COG1620	l-lactate permease
IEC338SC_0542	COG2186	Transcriptional regulator
IEC338SC_0544	COG0277	FAD linked oxidase domain protein
IEC338SC_0545	COG1448	Aminotransferase
IEC338SC_0546	COG1802	Transcriptional regulator
IEC338SC_0549	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IEC338SC_0552	COG1051	belongs to the nudix hydrolase family
IEC338SC_0558	COG2801	Transposase and inactivated derivatives
IEC338SC_0562	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEC338SC_0564	COG1309	transcriptional regulator
IEC338SC_0570	COG0564	pseudouridine synthase activity
IEC338SC_0575	COG1522	sequence-specific DNA binding
IEC338SC_0578	COG0251	oxidation-reduction process
IEC338SC_0579	COG1113	amino acid transport
IEC338SC_0580	COG1113	amino acid transport
IEC338SC_0584	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEC338SC_0585	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_0586	COG1024	Enoyl-CoA hydratase
IEC338SC_0587	COG1024	Enoyl-CoA hydratase
IEC338SC_0588	COG0477	Major facilitator Superfamily
IEC338SC_0589	COG3916	Acyl-homoserine-lactone synthase
IEC338SC_0591	COG2197	response regulator
IEC338SC_0593	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_0594	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEC338SC_0594	COG3321	synthase
IEC338SC_0594	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IEC338SC_0594	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IEC338SC_0602	COG0271	Belongs to the BolA IbaG family
IEC338SC_0604	COG1192	Involved in chromosome partitioning
IEC338SC_0607	COG0586	Pfam SNARE associated Golgi protein
IEC338SC_0608	COG2259	Doxx family
IEC338SC_0609	COG4399	Belongs to the UPF0754 family
IEC338SC_0610	COG0519	Catalyzes the synthesis of GMP from XMP
IEC338SC_0610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IEC338SC_0611	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IEC338SC_0621	COG0281	malic enzyme
IEC338SC_0622	COG2837	iron assimilation
IEC338SC_0623	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_0624	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IEC338SC_0625	COG1121	(ABC) transporter
IEC338SC_0633	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEC338SC_0635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEC338SC_0638	COG0386	Belongs to the glutathione peroxidase family
IEC338SC_0642	COG1309	transcriptional regulator
IEC338SC_0643	COG0697	spore germination
IEC338SC_0645	COG0758	DNA mediated transformation
IEC338SC_0652	COG1309	transcriptional regulator
IEC338SC_0659	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEC338SC_0662	COG0655	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_0670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEC338SC_0672	COG2814	Major facilitator Superfamily
IEC338SC_0674	COG1253	flavin adenine dinucleotide binding
IEC338SC_0676	COG2860	membrane
IEC338SC_0677	COG0477	Major facilitator Superfamily
IEC338SC_0679	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_0682	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IEC338SC_0686	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEC338SC_0687	COG0235	Class ii aldolase
IEC338SC_0688	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_0690	COG0606	chelatase, subunit chli
IEC338SC_0692	COG0347	Belongs to the P(II) protein family
IEC338SC_0693	COG0004	ammonium transporteR
IEC338SC_0695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEC338SC_0695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEC338SC_0703	COG0795	lipopolysaccharide-transporting ATPase activity
IEC338SC_0704	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEC338SC_0705	COG0793	Belongs to the peptidase S41A family
IEC338SC_0708	COG2197	response regulator
IEC338SC_0710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IEC338SC_0712	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEC338SC_0713	COG4974	Belongs to the 'phage' integrase family
IEC338SC_0718	COG0772	Belongs to the SEDS family
IEC338SC_0719	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEC338SC_0720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IEC338SC_0721	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IEC338SC_0726	COG0697	spore germination
IEC338SC_0727	COG1538	Outer membrane efflux protein
IEC338SC_0731	COG3275	phosphorelay sensor kinase activity
IEC338SC_0733	COG0181	hydroxymethylbilane synthase activity
IEC338SC_0742	COG1716	ATPase activity
IEC338SC_0743	COG0546	phosphoglycolate phosphatase activity
IEC338SC_0749	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEC338SC_0763	COG2056	Na+-H+ antiporter family
IEC338SC_0766	COG0326	Molecular chaperone. Has ATPase activity
IEC338SC_0769	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IEC338SC_0782	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEC338SC_0783	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEC338SC_0783	COG2169	Transcriptional regulator
IEC338SC_0789	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEC338SC_0791	COG0497	DNA recombination
IEC338SC_0794	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEC338SC_0796	COG0237	dephospho-CoA kinase activity
IEC338SC_0806	COG0195	Participates in both transcription termination and antitermination
IEC338SC_0808	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEC338SC_0810	COG2212	antiporter activity
IEC338SC_0812	COG0651	ATP synthesis coupled electron transport
IEC338SC_0813	COG1006	Multisubunit Na H antiporter MnhC subunit
IEC338SC_0814	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IEC338SC_0814	COG2111	Na H antiporter
IEC338SC_0817	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IEC338SC_0820	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IEC338SC_0822	COG2226	methyltransferase
IEC338SC_0826	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IEC338SC_0827	COG1074	ATP-dependent DNA helicase activity
IEC338SC_0828	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IEC338SC_0831	COG1185	polyribonucleotide nucleotidyltransferase activity
IEC338SC_0832	COG0598	Magnesium transport protein CorA
IEC338SC_0833	COG0789	Transcriptional regulator
IEC338SC_0834	COG0484	heat shock protein binding
IEC338SC_0836	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEC338SC_0838	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEC338SC_0842	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEC338SC_0844	COG4535	Mg2 and Co2 transporter CorC
IEC338SC_0847	COG0644	oxidoreductase
IEC338SC_0847	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IEC338SC_0849	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IEC338SC_0852	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_0853	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IEC338SC_0861	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IEC338SC_0864	COG0534	Mate efflux family protein
IEC338SC_0866	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IEC338SC_0867	COG4221	oxidoreductase activity
IEC338SC_0868	COG0583	DNA-binding transcription factor activity
IEC338SC_0872	COG1530	ribonuclease E activity
IEC338SC_0875	COG2378	regulation of single-species biofilm formation
IEC338SC_0876	COG0625	glutathione transferase activity
IEC338SC_0878	COG0583	DNA-binding transcription factor activity
IEC338SC_0886	COG0583	DNA-binding transcription factor activity
IEC338SC_0891	COG0473	3-isopropylmalate dehydrogenase activity
IEC338SC_0902	COG1301	dicarboxylic acid transport
IEC338SC_0904	COG1560	Kdo2-lipid A biosynthetic process
IEC338SC_0907	COG2900	Belongs to the SlyX family
IEC338SC_0908	COG0604	alcohol dehydrogenase
IEC338SC_0909	COG1733	regulation of RNA biosynthetic process
IEC338SC_0914	COG0210	DNA helicase
IEC338SC_0919	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IEC338SC_0919	COG4651	solute:proton antiporter activity
IEC338SC_0920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IEC338SC_0921	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IEC338SC_0924	COG0788	formyltetrahydrofolate deformylase activity
IEC338SC_0944	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEC338SC_0944	COG2813	Specifically methylates the guanine in position
IEC338SC_0946	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IEC338SC_0948	COG4774	siderophore transport
IEC338SC_0950	COG0740	serine-type endopeptidase activity
IEC338SC_0954	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IEC338SC_0954	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IEC338SC_0955	COG0280	phosphate acetyltransferase
IEC338SC_0955	COG0857	belongs to the CobB CobQ family
IEC338SC_0956	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEC338SC_0958	COG0800	Aldolase
IEC338SC_0960	COG3265	gluconokinase activity
IEC338SC_0961	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_0963	COG2267	carboxylic ester hydrolase activity
IEC338SC_0966	COG0793	Belongs to the peptidase S41A family
IEC338SC_0973	COG1426	Protein conserved in bacteria
IEC338SC_0977	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEC338SC_0981	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEC338SC_0982	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEC338SC_0985	COG1216	Glycosyl transferase, family 2
IEC338SC_0987	COG2986	histidine ammonia-lyase
IEC338SC_0995	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_0996	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IEC338SC_1000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IEC338SC_1002	COG1162	GTPase activity
IEC338SC_1003	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IEC338SC_1007	COG0577	efflux transmembrane transporter activity
IEC338SC_1007	COG1136	(ABC) transporter
IEC338SC_1008	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_1012	COG0028	Belongs to the TPP enzyme family
IEC338SC_1013	COG0440	acetolactate synthase activity
IEC338SC_1014	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IEC338SC_1016	COG1309	transcriptional regulator
IEC338SC_1018	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IEC338SC_1021	COG0084	hydrolase, TatD family'
IEC338SC_1023	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IEC338SC_1024	COG0583	DNA-binding transcription factor activity
IEC338SC_1027	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEC338SC_1028	COG2814	Major facilitator Superfamily
IEC338SC_1030	COG0697	spore germination
IEC338SC_1031	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IEC338SC_1032	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IEC338SC_1033	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IEC338SC_1037	COG3622	Belongs to the hyi family
IEC338SC_1038	COG2084	Dehydrogenase
IEC338SC_1039	COG1024	Enoyl-CoA hydratase
IEC338SC_1040	COG0784	Response regulator, receiver
IEC338SC_1040	COG2205	protein histidine kinase activity
IEC338SC_1040	COG5002	protein histidine kinase activity
IEC338SC_1041	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IEC338SC_1044	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEC338SC_1049	COG4221	oxidoreductase activity
IEC338SC_1050	COG3956	TIGRFAM MazG family protein
IEC338SC_1051	COG1555	photosystem II stabilization
IEC338SC_1052	COG0617	tRNA 3'-terminal CCA addition
IEC338SC_1053	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IEC338SC_1057	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEC338SC_1058	COG3028	Belongs to the UPF0307 family
IEC338SC_1059	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_1062	COG0625	glutathione transferase activity
IEC338SC_1063	COG1238	metal cluster binding
IEC338SC_1065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IEC338SC_1066	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEC338SC_1069	COG0072	phenylalanine-tRNA ligase activity
IEC338SC_1074	COG0248	Ppx GppA phosphatase
IEC338SC_1076	COG0037	tRNA processing
IEC338SC_1079	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEC338SC_1079	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEC338SC_1084	COG1764	response to oxidative stress
IEC338SC_1085	COG1846	Transcriptional regulator
IEC338SC_1087	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEC338SC_1099	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEC338SC_1100	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IEC338SC_1101	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEC338SC_1113	COG1214	PFAM Peptidase M22, glycoprotease
IEC338SC_1118	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IEC338SC_1119	COG0561	phosphatase activity
IEC338SC_1121	COG2132	Multicopper oxidase
IEC338SC_1125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEC338SC_1126	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEC338SC_1127	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IEC338SC_1133	COG1063	alcohol dehydrogenase
IEC338SC_1134	COG0583	DNA-binding transcription factor activity
IEC338SC_1135	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_1136	COG2814	Major facilitator Superfamily
IEC338SC_1137	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IEC338SC_1142	COG1053	succinate dehydrogenase
IEC338SC_1143	COG0583	DNA-binding transcription factor activity
IEC338SC_1146	COG0583	DNA-binding transcription factor activity
IEC338SC_1152	COG0583	DNA-binding transcription factor activity
IEC338SC_1154	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IEC338SC_1155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_1166	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEC338SC_1169	COG0745	RESPONSE REGULATOR receiver
IEC338SC_1170	COG2205	protein histidine kinase activity
IEC338SC_1172	COG2199	diguanylate cyclase activity
IEC338SC_1177	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IEC338SC_1183	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IEC338SC_1184	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IEC338SC_1188	COG0583	DNA-binding transcription factor activity
IEC338SC_1192	COG0668	transmembrane transport
IEC338SC_1194	COG2081	HI0933 family
IEC338SC_1195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IEC338SC_1202	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEC338SC_1202	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEC338SC_1204	COG0489	protein tyrosine kinase activity
IEC338SC_1205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEC338SC_1214	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEC338SC_1216	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEC338SC_1219	COG0730	response to heat
IEC338SC_1221	COG1196	nuclear chromosome segregation
IEC338SC_1225	COG2223	nitrite transmembrane transporter activity
IEC338SC_1226	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IEC338SC_1228	COG2226	methyltransferase
IEC338SC_1228	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEC338SC_1228	COG0596	Alpha beta hydrolase
IEC338SC_1231	COG4106	trans-aconitate 2-methyltransferase activity
IEC338SC_1234	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEC338SC_1235	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEC338SC_1236	COG0009	L-threonylcarbamoyladenylate synthase
IEC338SC_1237	COG3101	peptidyl-lysine hydroxylation
IEC338SC_1238	COG1399	metal-binding, possibly nucleic acid-binding protein
IEC338SC_1241	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1243	COG1652	LysM domain
IEC338SC_1244	COG0351	phosphomethylpyrimidine kinase
IEC338SC_1246	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IEC338SC_1252	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEC338SC_1257	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IEC338SC_1260	COG0358	DNA primase activity
IEC338SC_1267	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEC338SC_1270	COG0583	DNA-binding transcription factor activity
IEC338SC_1271	COG0473	3-isopropylmalate dehydrogenase activity
IEC338SC_1274	COG4638	Rieske (2fe-2S)
IEC338SC_1275	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_1279	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IEC338SC_1279	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEC338SC_1284	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEC338SC_1286	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEC338SC_1287	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEC338SC_1290	COG0456	acetyltransferase
IEC338SC_1292	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IEC338SC_1293	COG0492	ferredoxin-NADP+ reductase activity
IEC338SC_1294	COG1674	ftsk spoiiie
IEC338SC_1295	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_1298	COG2894	cell division
IEC338SC_1301	COG0204	Acyl-transferase
IEC338SC_1302	COG2885	chlorophyll binding
IEC338SC_1303	COG0210	DNA helicase
IEC338SC_1305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEC338SC_1308	COG0121	glutamine amidotransferase
IEC338SC_1311	COG2914	Belongs to the UPF0125 (RnfH) family
IEC338SC_1312	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEC338SC_1313	COG0735	belongs to the Fur family
IEC338SC_1320	COG0420	3'-5' exonuclease activity
IEC338SC_1324	COG1090	epimerase
IEC338SC_1327	COG2050	protein possibly involved in aromatic compounds catabolism
IEC338SC_1329	COG2814	Major facilitator Superfamily
IEC338SC_1330	COG0405	Gamma-glutamyltransferase
IEC338SC_1332	COG0582	viral genome integration into host DNA
IEC338SC_1345	COG0210	DNA helicase
IEC338SC_1349	COG0210	DNA helicase
IEC338SC_1359	COG2801	Transposase and inactivated derivatives
IEC338SC_1361	COG0477	Major facilitator Superfamily
IEC338SC_1362	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEC338SC_1372	COG0531	amino acid
IEC338SC_1373	COG2040	homocysteine
IEC338SC_1378	COG1309	transcriptional regulator
IEC338SC_1379	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEC338SC_1380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IEC338SC_1382	COG1607	acyl-coa hydrolase
IEC338SC_1384	COG0523	cobalamin synthesis protein
IEC338SC_1386	COG4681	YaeQ
IEC338SC_1388	COG1649	PFAM Uncharacterised BCR, COG1649
IEC338SC_1388	COG0726	polysaccharide deacetylase
IEC338SC_1389	COG1215	transferase activity, transferring glycosyl groups
IEC338SC_1391	COG1024	Enoyl-CoA hydratase
IEC338SC_1394	COG1414	Transcriptional regulator
IEC338SC_1398	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1401	COG2271	Major facilitator Superfamily
IEC338SC_1403	COG2267	carboxylic ester hydrolase activity
IEC338SC_1404	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1407	COG0028	Belongs to the TPP enzyme family
IEC338SC_1409	COG0477	Major facilitator Superfamily
IEC338SC_1410	COG0242	peptide deformylase activity
IEC338SC_1411	COG2066	Belongs to the glutaminase family
IEC338SC_1412	COG2207	Transcriptional regulator
IEC338SC_1413	COG2223	nitrite transmembrane transporter activity
IEC338SC_1418	COG0306	phosphate transporter
IEC338SC_1422	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IEC338SC_1426	COG4771	TonB-dependent receptor
IEC338SC_1431	COG4181	ATPase activity
IEC338SC_1432	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IEC338SC_1437	COG0583	DNA-binding transcription factor activity
IEC338SC_1438	COG2267	carboxylic ester hydrolase activity
IEC338SC_1439	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_1440	COG1773	rubredoxin
IEC338SC_1450	COG2851	Citrate transporter
IEC338SC_1451	COG1253	flavin adenine dinucleotide binding
IEC338SC_1454	COG3015	lipoprotein NlpE involved in copper resistance
IEC338SC_1459	COG0804	urea catabolic process
IEC338SC_1461	COG0830	nickel cation binding
IEC338SC_1465	COG0742	ribosomal rna small subunit methyltransferase
IEC338SC_1466	COG0768	penicillin binding
IEC338SC_1472	COG0714	Associated with various cellular activities
IEC338SC_1473	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IEC338SC_1474	COG3552	Protein containing von Willebrand factor type A (VWA) domain
IEC338SC_1475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEC338SC_1476	COG2878	Part of a membrane complex involved in electron transport
IEC338SC_1477	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IEC338SC_1479	COG3384	dioxygenase
IEC338SC_1482	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEC338SC_1488	COG0006	proline dipeptidase activity
IEC338SC_1489	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_1490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_1492	COG0789	Transcriptional regulator
IEC338SC_1494	COG1279	arginine transmembrane transporter activity
IEC338SC_1495	COG0583	DNA-binding transcription factor activity
IEC338SC_1503	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEC338SC_1504	COG0741	lytic transglycosylase activity
IEC338SC_1504	COG1388	LysM domain
IEC338SC_1505	COG4166	transmembrane transport
IEC338SC_1506	COG4174	ABC transporter (Permease)
IEC338SC_1507	COG4239	(ABC) transporter, permease
IEC338SC_1508	COG4172	Belongs to the ABC transporter superfamily
IEC338SC_1512	COG0582	viral genome integration into host DNA
IEC338SC_1528	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEC338SC_1530	COG4251	negative regulation of phosphorylation
IEC338SC_1530	COG3706	GGDEF domain
IEC338SC_1530	COG5001	Diguanylate cyclase
IEC338SC_1530	COG2203	Gaf domain
IEC338SC_1533	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_1533	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_1535	COG1309	transcriptional regulator
IEC338SC_1537	COG0251	oxidation-reduction process
IEC338SC_1539	COG0583	DNA-binding transcription factor activity
IEC338SC_1544	COG4269	membrane
IEC338SC_1548	COG3501	Rhs element vgr protein
IEC338SC_1555	COG1113	amino acid transport
IEC338SC_1557	COG0531	amino acid
IEC338SC_1561	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_1565	COG1113	amino acid transport
IEC338SC_1566	COG2831	hemolysin activation secretion protein
IEC338SC_1567	COG3210	domain, Protein
IEC338SC_1575	COG0697	spore germination
IEC338SC_1580	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_1582	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_1583	COG1024	Enoyl-CoA hydratase
IEC338SC_1584	COG2814	Major facilitator Superfamily
IEC338SC_1587	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_1590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IEC338SC_1594	COG1944	ATP diphosphatase activity
IEC338SC_1601	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IEC338SC_1603	COG0583	DNA-binding transcription factor activity
IEC338SC_1604	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IEC338SC_1605	COG2072	flavoprotein involved in K transport
IEC338SC_1608	COG1309	transcriptional regulator
IEC338SC_1609	COG1741	Belongs to the pirin family
IEC338SC_1611	COG2252	PERMEase
IEC338SC_1612	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IEC338SC_1613	COG3038	cytochrome b561
IEC338SC_1615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEC338SC_1619	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IEC338SC_1621	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEC338SC_1624	COG0667	Aldo Keto reductase
IEC338SC_1626	COG1765	OsmC-like protein
IEC338SC_1629	COG0542	response to heat
IEC338SC_1636	COG2885	chlorophyll binding
IEC338SC_1638	COG0625	glutathione transferase activity
IEC338SC_1640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IEC338SC_1644	COG3634	alkyl hydroperoxide reductase activity
IEC338SC_1648	COG0450	alkyl hydroperoxide reductase
IEC338SC_1649	COG1643	Atp-dependent helicase
IEC338SC_1652	COG2814	Major facilitator Superfamily
IEC338SC_1653	COG3135	benzoate transporter
IEC338SC_1654	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1655	COG0633	Ferredoxin
IEC338SC_1655	COG0543	2 iron, 2 sulfur cluster binding
IEC338SC_1656	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEC338SC_1657	COG4638	Rieske (2fe-2S)
IEC338SC_1658	COG0583	DNA-binding transcription factor activity
IEC338SC_1660	COG2871	sodium ion transport
IEC338SC_1676	COG1570	exodeoxyribonuclease VII activity
IEC338SC_1683	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_1684	COG1560	Kdo2-lipid A biosynthetic process
IEC338SC_1685	COG1278	Cold shock
IEC338SC_1690	COG2226	methyltransferase
IEC338SC_1695	COG2801	Transposase and inactivated derivatives
IEC338SC_1697	COG1309	transcriptional regulator
IEC338SC_1705	COG0668	transmembrane transport
IEC338SC_1707	COG2814	Major facilitator Superfamily
IEC338SC_1708	COG1733	regulation of RNA biosynthetic process
IEC338SC_1714	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEC338SC_1720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IEC338SC_1722	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IEC338SC_1723	COG1137	ATPase activity
IEC338SC_1724	COG1538	Outer membrane efflux protein
IEC338SC_1730	COG4122	O-methyltransferase activity
IEC338SC_1732	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IEC338SC_1735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_1738	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEC338SC_1739	COG0531	amino acid
IEC338SC_1740	COG1522	sequence-specific DNA binding
IEC338SC_1743	COG2207	Transcriptional regulator
IEC338SC_1745	COG2801	Transposase and inactivated derivatives
IEC338SC_1749	COG1733	regulation of RNA biosynthetic process
IEC338SC_1750	COG0753	catalase activity
IEC338SC_1751	COG3038	cytochrome b561
IEC338SC_1752	COG2271	Major facilitator Superfamily
IEC338SC_1756	COG0583	DNA-binding transcription factor activity
IEC338SC_1757	COG0402	S-adenosylhomocysteine deaminase activity
IEC338SC_1765	COG1309	transcriptional regulator
IEC338SC_1766	COG1051	belongs to the nudix hydrolase family
IEC338SC_1770	COG3209	COG3209 Rhs family protein
IEC338SC_1783	COG3220	belongs to the UPF0276 family
IEC338SC_1785	COG1595	DNA-templated transcription, initiation
IEC338SC_1787	COG0583	DNA-binding transcription factor activity
IEC338SC_1788	COG1914	H( )-stimulated, divalent metal cation uptake system
IEC338SC_1792	COG4770	biotin carboxylase activity
IEC338SC_1793	COG0038	chloride channel
IEC338SC_1794	COG2831	hemolysin activation secretion protein
IEC338SC_1795	COG3210	domain, Protein
IEC338SC_1798	COG2801	Transposase and inactivated derivatives
IEC338SC_1803	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEC338SC_1804	COG1063	alcohol dehydrogenase
IEC338SC_1807	COG0439	Biotin carboxylase
IEC338SC_1808	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_1809	COG1733	regulation of RNA biosynthetic process
IEC338SC_1812	COG0864	Transcriptional regulator
IEC338SC_1814	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_1815	COG1116	anion transmembrane transporter activity
IEC338SC_1821	COG3209	COG3209 Rhs family protein
IEC338SC_1828	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IEC338SC_1839	COG2885	chlorophyll binding
IEC338SC_1849	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_1850	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IEC338SC_1852	COG0789	Transcriptional regulator
IEC338SC_1855	COG1760	l-serine dehydratase
IEC338SC_1856	COG2030	dehydratase
IEC338SC_1856	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_1857	COG3396	Phenylacetate-CoA oxygenase
IEC338SC_1858	COG3460	Phenylacetate-CoA oxygenase
IEC338SC_1859	COG3396	Phenylacetate-CoA oxygenase
IEC338SC_1860	COG2151	metal-sulfur cluster biosynthetic enzyme
IEC338SC_1861	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_1862	COG1024	Enoyl-CoA hydratase
IEC338SC_1863	COG1024	Enoyl-CoA hydratase
IEC338SC_1864	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEC338SC_1865	COG0183	Belongs to the thiolase family
IEC338SC_1866	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IEC338SC_1867	COG3327	negative regulation of DNA-templated transcription, initiation
IEC338SC_1874	COG0406	alpha-ribazole phosphatase activity
IEC338SC_1880	COG0583	DNA-binding transcription factor activity
IEC338SC_1882	COG1414	Transcriptional regulator
IEC338SC_1883	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IEC338SC_1885	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_1887	COG1840	ABC-type Fe3 transport system, periplasmic component
IEC338SC_1888	COG3842	ATPase activity
IEC338SC_1891	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IEC338SC_1892	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IEC338SC_1893	COG2814	Major facilitator Superfamily
IEC338SC_1894	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_1897	COG1024	Enoyl-CoA hydratase
IEC338SC_1899	COG2814	Major facilitator Superfamily
IEC338SC_1901	COG0183	Belongs to the thiolase family
IEC338SC_1902	COG1250	3-hydroxyacyl-CoA dehydrogenase
IEC338SC_1903	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1904	COG1024	Enoyl-CoA hydratase
IEC338SC_1905	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_1906	COG2814	Major facilitator Superfamily
IEC338SC_1907	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEC338SC_1908	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEC338SC_1910	COG2814	Major facilitator Superfamily
IEC338SC_1912	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_1915	COG0583	DNA-binding transcription factor activity
IEC338SC_1918	COG1024	Enoyl-CoA hydratase
IEC338SC_1919	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IEC338SC_1920	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_1921	COG1309	transcriptional regulator
IEC338SC_1922	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_1925	COG2814	Major facilitator Superfamily
IEC338SC_1927	COG0583	DNA-binding transcription factor activity
IEC338SC_1937	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1941	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEC338SC_1945	COG0784	Response regulator, receiver
IEC338SC_1945	COG2205	protein histidine kinase activity
IEC338SC_1948	COG0765	amino acid transport
IEC338SC_1949	COG0765	amino acid transport
IEC338SC_1951	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_1952	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_1954	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_1955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEC338SC_1956	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEC338SC_1957	COG1045	serine acetyltransferase
IEC338SC_1959	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_1960	COG0583	DNA-binding transcription factor activity
IEC338SC_1961	COG0625	glutathione transferase activity
IEC338SC_1962	COG0625	glutathione transferase activity
IEC338SC_1963	COG0583	DNA-binding transcription factor activity
IEC338SC_1965	COG1346	cytolysis
IEC338SC_1969	COG2814	Major facilitator Superfamily
IEC338SC_1971	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IEC338SC_1972	COG3052	prosthetic group binding
IEC338SC_1976	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IEC338SC_1980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_1982	COG1294	oxidase, subunit
IEC338SC_1983	COG1271	oxidase subunit
IEC338SC_1987	COG0477	Major facilitator Superfamily
IEC338SC_1989	COG4521	taurine ABC transporter
IEC338SC_1990	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IEC338SC_1991	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEC338SC_1992	COG2175	clavaminate synthase activity
IEC338SC_1994	COG1953	Uracil, thiamine, allantoin
IEC338SC_1996	COG0583	DNA-binding transcription factor activity
IEC338SC_1999	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IEC338SC_2002	COG0640	Transcriptional regulator
IEC338SC_2004	COG0798	PFAM Bile acid sodium symporter
IEC338SC_2005	COG0431	NADPH-dependent FMN reductase
IEC338SC_2006	COG0583	DNA-binding transcription factor activity
IEC338SC_2009	COG3634	alkyl hydroperoxide reductase activity
IEC338SC_2016	COG1301	dicarboxylic acid transport
IEC338SC_2017	COG0436	Aminotransferase
IEC338SC_2019	COG0386	Belongs to the glutathione peroxidase family
IEC338SC_2027	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IEC338SC_2032	COG0012	GTP binding
IEC338SC_2033	COG2011	ABC-type metal ion transport system permease component
IEC338SC_2034	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEC338SC_2036	COG1464	Belongs to the NlpA lipoprotein family
IEC338SC_2042	COG0765	amino acid transport
IEC338SC_2043	COG0765	amino acid transport
IEC338SC_2044	COG1126	abc transporter atp-binding protein
IEC338SC_2046	COG1522	sequence-specific DNA binding
IEC338SC_2049	COG1309	transcriptional regulator
IEC338SC_2052	COG0583	DNA-binding transcription factor activity
IEC338SC_2054	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IEC338SC_2056	COG0697	spore germination
IEC338SC_2057	COG0583	DNA-binding transcription factor activity
IEC338SC_2060	COG3121	Chaperone
IEC338SC_2061	COG3539	Fimbrial protein
IEC338SC_2066	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IEC338SC_2066	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEC338SC_2075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEC338SC_2077	COG2353	YceI-like domain
IEC338SC_2079	COG3698	Phosphodiester glycosidase
IEC338SC_2082	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEC338SC_2083	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IEC338SC_2083	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IEC338SC_2083	COG0506	proline dehydrogenase activity
IEC338SC_2085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEC338SC_2086	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEC338SC_2090	COG1132	(ABC) transporter
IEC338SC_2092	COG3122	Protein conserved in bacteria
IEC338SC_2093	COG3619	membrane
IEC338SC_2095	COG0640	Transcriptional regulator
IEC338SC_2097	COG2850	peptidyl-arginine hydroxylation
IEC338SC_2098	COG0424	maF-like protein
IEC338SC_2103	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IEC338SC_2105	COG3178	'Phosphotransferase
IEC338SC_2106	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IEC338SC_2108	COG1192	Involved in chromosome partitioning
IEC338SC_2109	COG1475	DNA binding
IEC338SC_2110	COG0811	peptide transport
IEC338SC_2112	COG1132	(ABC) transporter
IEC338SC_2113	COG1663	tetraacyldisaccharide 4'-kinase activity
IEC338SC_2117	COG0084	hydrolase, TatD family'
IEC338SC_2126	COG0590	tRNA wobble adenosine to inosine editing
IEC338SC_2130	COG0776	regulation of translation
IEC338SC_2133	COG2431	L-lysine efflux transmembrane transporter activity
IEC338SC_2136	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IEC338SC_2137	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IEC338SC_2142	COG4206	TonB-dependent receptor
IEC338SC_2144	COG4166	transmembrane transport
IEC338SC_2145	COG0339	signal peptide processing
IEC338SC_2146	COG0601	transmembrane transport
IEC338SC_2154	COG0702	epimerase
IEC338SC_2155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IEC338SC_2159	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEC338SC_2165	COG0316	Belongs to the HesB IscA family
IEC338SC_2166	COG0822	iron-sulfur transferase activity
IEC338SC_2171	COG0776	regulation of translation
IEC338SC_2172	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IEC338SC_2173	COG2207	Transcriptional regulator
IEC338SC_2174	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEC338SC_2175	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_2176	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_2179	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEC338SC_2180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IEC338SC_2183	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IEC338SC_2187	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IEC338SC_2188	COG0730	response to heat
IEC338SC_2191	COG4773	Receptor
IEC338SC_2192	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IEC338SC_2204	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEC338SC_2206	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEC338SC_2207	COG0583	DNA-binding transcription factor activity
IEC338SC_2213	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEC338SC_2215	COG0133	tryptophan synthase activity
IEC338SC_2219	COG3706	GGDEF domain
IEC338SC_2222	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEC338SC_2223	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IEC338SC_2224	COG0022	dehydrogenase e1 component
IEC338SC_2225	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEC338SC_2226	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_2228	COG1063	alcohol dehydrogenase
IEC338SC_2229	COG3781	membrane
IEC338SC_2231	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_2231	COG3453	Protein conserved in bacteria
IEC338SC_2233	COG0730	response to heat
IEC338SC_2236	COG3708	Transcriptional regulator
IEC338SC_2236	COG2207	Transcriptional regulator
IEC338SC_2238	COG0477	Major facilitator Superfamily
IEC338SC_2240	COG1027	Aspartate ammonia-lyase
IEC338SC_2243	COG0583	DNA-binding transcription factor activity
IEC338SC_2244	COG0583	DNA-binding transcription factor activity
IEC338SC_2245	COG0183	Belongs to the thiolase family
IEC338SC_2246	COG2031	fatty acid transporter
IEC338SC_2249	COG0583	DNA-binding transcription factor activity
IEC338SC_2260	COG2610	gluconate transmembrane transporter activity
IEC338SC_2261	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2262	COG2207	Transcriptional regulator
IEC338SC_2265	COG0412	Dienelactone hydrolase
IEC338SC_2266	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2268	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_2271	COG0543	2 iron, 2 sulfur cluster binding
IEC338SC_2271	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_2272	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEC338SC_2273	COG4638	Rieske (2fe-2S)
IEC338SC_2275	COG0725	ABC transporter, periplasmic molybdate-binding protein
IEC338SC_2276	COG4149	molybdate abc transporter
IEC338SC_2277	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IEC338SC_2278	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2279	COG3433	isochorismatase activity
IEC338SC_2279	COG1535	isochorismatase
IEC338SC_2289	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEC338SC_2290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_2291	COG0745	RESPONSE REGULATOR receiver
IEC338SC_2292	COG2205	protein histidine kinase activity
IEC338SC_2294	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEC338SC_2299	COG0753	catalase activity
IEC338SC_2302	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IEC338SC_2307	COG3539	Fimbrial protein
IEC338SC_2314	COG0583	DNA-binding transcription factor activity
IEC338SC_2315	COG0402	S-adenosylhomocysteine deaminase activity
IEC338SC_2317	COG1609	Transcriptional regulator
IEC338SC_2317	COG2207	Transcriptional regulator
IEC338SC_2320	COG1271	oxidase subunit
IEC338SC_2321	COG1294	oxidase, subunit
IEC338SC_2324	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IEC338SC_2325	COG2814	Major facilitator Superfamily
IEC338SC_2327	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IEC338SC_2329	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_2330	COG3118	belongs to the thioredoxin family
IEC338SC_2331	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2332	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEC338SC_2336	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_2341	COG1414	Transcriptional regulator
IEC338SC_2342	COG4977	sequence-specific DNA binding
IEC338SC_2342	COG1917	Cupin 2, conserved barrel domain protein
IEC338SC_2344	COG1535	isochorismatase
IEC338SC_2344	COG3433	isochorismatase activity
IEC338SC_2345	COG4628	conserved protein (DUF2132)
IEC338SC_2352	COG3210	domain, Protein
IEC338SC_2357	COG2801	Transposase and inactivated derivatives
IEC338SC_2374	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEC338SC_2378	COG1120	ATPase activity
IEC338SC_2393	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IEC338SC_2394	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IEC338SC_2399	COG0583	DNA-binding transcription factor activity
IEC338SC_2411	COG1309	transcriptional regulator
IEC338SC_2413	COG0318	PFAM AMP-dependent synthetase and ligase
IEC338SC_2415	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_2417	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2418	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2419	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2420	COG0583	DNA-binding transcription factor activity
IEC338SC_2421	COG1309	transcriptional regulator
IEC338SC_2425	COG0789	Transcriptional regulator
IEC338SC_2427	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEC338SC_2429	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_2429	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_2433	COG0583	DNA-binding transcription factor activity
IEC338SC_2434	COG2814	Major facilitator Superfamily
IEC338SC_2435	COG2814	Major facilitator Superfamily
IEC338SC_2436	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_2437	COG3384	dioxygenase
IEC338SC_2438	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2440	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEC338SC_2441	COG4638	Rieske (2fe-2S)
IEC338SC_2442	COG0583	DNA-binding transcription factor activity
IEC338SC_2446	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IEC338SC_2447	COG3971	2-oxopent-4-enoate hydratase activity
IEC338SC_2449	COG0583	DNA-binding transcription factor activity
IEC338SC_2450	COG4948	Mandelate Racemase Muconate Lactonizing
IEC338SC_2451	COG4829	muconolactone delta-isomerase
IEC338SC_2453	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEC338SC_2454	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEC338SC_2455	COG0183	Belongs to the thiolase family
IEC338SC_2456	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEC338SC_2457	COG1012	belongs to the aldehyde dehydrogenase family
IEC338SC_2459	COG3733	amine oxidase
IEC338SC_2461	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_2463	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_2465	COG4638	Rieske (2fe-2S)
IEC338SC_2469	COG0154	amidase activity
IEC338SC_2471	COG2814	Major facilitator Superfamily
IEC338SC_2476	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_2477	COG0583	DNA-binding transcription factor activity
IEC338SC_2478	COG1414	Transcriptional regulator
IEC338SC_2481	COG2391	methyltransferase activity
IEC338SC_2483	COG4993	Dehydrogenase
IEC338SC_2484	COG3659	wide pore channel activity
IEC338SC_2485	COG3420	alginic acid biosynthetic process
IEC338SC_2486	COG0710	3-dehydroquinate dehydratase activity
IEC338SC_2487	COG3485	protocatechuate 3,4-dioxygenase
IEC338SC_2488	COG3485	protocatechuate 3,4-dioxygenase
IEC338SC_2489	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEC338SC_2490	COG2271	Major facilitator Superfamily
IEC338SC_2491	COG0596	Alpha beta hydrolase
IEC338SC_2492	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEC338SC_2493	COG0183	Belongs to the thiolase family
IEC338SC_2494	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEC338SC_2495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEC338SC_2497	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IEC338SC_2498	COG4773	Receptor
IEC338SC_2500	COG2323	membrane
IEC338SC_2501	COG0148	phosphopyruvate hydratase activity
IEC338SC_2510	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEC338SC_2510	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_2513	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IEC338SC_2515	COG0542	response to heat
IEC338SC_2516	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IEC338SC_2522	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEC338SC_2523	COG0569	domain protein
IEC338SC_2524	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IEC338SC_2527	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEC338SC_2529	COG1585	Membrane protein implicated in regulation of membrane protease activity
IEC338SC_2532	COG1294	oxidase, subunit
IEC338SC_2533	COG4890	Cyd operon protein YbgT
IEC338SC_2538	COG0552	protein localization to endoplasmic reticulum
IEC338SC_2543	COG0517	IMP dehydrogenase activity
IEC338SC_2543	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IEC338SC_2544	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEC338SC_2545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IEC338SC_2547	COG0583	DNA-binding transcription factor activity
IEC338SC_2548	COG0024	Methionine aminopeptidase
IEC338SC_2554	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEC338SC_2554	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEC338SC_2555	COG1105	Belongs to the carbohydrate kinase PfkB family
IEC338SC_2556	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEC338SC_2556	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IEC338SC_2556	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IEC338SC_2559	COG5001	Diguanylate cyclase
IEC338SC_2559	COG3300	MHYT domain
IEC338SC_2563	COG0659	secondary active sulfate transmembrane transporter activity
IEC338SC_2567	COG1113	amino acid transport
IEC338SC_2569	COG1522	sequence-specific DNA binding
IEC338SC_2572	COG1011	Hydrolase
IEC338SC_2573	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IEC338SC_2575	COG2137	regulation of response to DNA damage stimulus
IEC338SC_2577	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IEC338SC_2581	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IEC338SC_2584	COG0575	Belongs to the CDS family
IEC338SC_2585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEC338SC_2589	COG3852	Histidine kinase
IEC338SC_2590	COG2204	response regulator
IEC338SC_2600	COG0596	Alpha beta hydrolase
IEC338SC_2603	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEC338SC_2608	COG0697	spore germination
IEC338SC_2609	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_2611	COG0303	'Molybdopterin
IEC338SC_2612	COG0315	cyclic pyranopterin monophosphate synthase activity
IEC338SC_2612	COG0521	Mo-molybdopterin cofactor biosynthetic process
IEC338SC_2615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IEC338SC_2616	COG0243	molybdopterin cofactor binding
IEC338SC_2618	COG0243	molybdopterin cofactor binding
IEC338SC_2619	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_2620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_2620	COG2146	nitrite reductase [NAD(P)H] activity
IEC338SC_2623	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_2623	COG1116	anion transmembrane transporter activity
IEC338SC_2627	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IEC338SC_2629	COG4264	IucA IucC family
IEC338SC_2630	COG4264	IucA IucC family
IEC338SC_2633	COG4264	IucA IucC family
IEC338SC_2637	COG0511	ligase activity, forming carbon-carbon bonds
IEC338SC_2640	COG2814	Major facilitator Superfamily
IEC338SC_2645	COG3179	chitinase
IEC338SC_2667	COG3566	protein conserved in bacteria
IEC338SC_2670	COG3567	Phage-associated protein, HI1409 family
IEC338SC_2671	COG5410	chromosome segregation
IEC338SC_2704	COG0069	glutamate synthase activity
IEC338SC_2710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEC338SC_2713	COG1335	isochorismatase
IEC338SC_2716	COG1454	alcohol dehydrogenase
IEC338SC_2717	COG0824	Thioesterase
IEC338SC_2719	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEC338SC_2727	COG0183	Belongs to the thiolase family
IEC338SC_2729	COG0583	DNA-binding transcription factor activity
IEC338SC_2730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IEC338SC_2732	COG1522	sequence-specific DNA binding
IEC338SC_2733	COG3135	benzoate transporter
IEC338SC_2737	COG0589	response to stress
IEC338SC_2738	COG0488	(ABC) transporter
IEC338SC_2744	COG0583	DNA-binding transcription factor activity
IEC338SC_2749	COG1733	regulation of RNA biosynthetic process
IEC338SC_2751	COG3772	lysozyme
IEC338SC_2760	COG4772	TonB-dependent receptor
IEC338SC_2761	COG1605	Chorismate mutase
IEC338SC_2769	COG0308	aminopeptidase N
IEC338SC_2774	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IEC338SC_2775	COG1454	alcohol dehydrogenase
IEC338SC_2779	COG0531	amino acid
IEC338SC_2780	COG4303	Ethanolamine ammonia lyase large subunit
IEC338SC_2781	COG4302	ethanolamine ammonia-lyase activity
IEC338SC_2782	COG0519	Catalyzes the synthesis of GMP from XMP
IEC338SC_2782	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IEC338SC_2783	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEC338SC_2788	COG0697	spore germination
IEC338SC_2789	COG1923	regulation of RNA biosynthetic process
IEC338SC_2791	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEC338SC_2792	COG0802	atpase or kinase
IEC338SC_2796	COG1187	pseudouridine synthase activity
IEC338SC_2799	COG0583	DNA-binding transcription factor activity
IEC338SC_2801	COG2814	Major facilitator Superfamily
IEC338SC_2802	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEC338SC_2804	COG0471	metal ion transport
IEC338SC_2811	COG0729	surface antigen
IEC338SC_2812	COG0477	Major facilitator Superfamily
IEC338SC_2815	COG0174	glutamine synthetase
IEC338SC_2816	COG0745	RESPONSE REGULATOR receiver
IEC338SC_2817	COG2205	protein histidine kinase activity
IEC338SC_2819	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IEC338SC_2820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IEC338SC_2823	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEC338SC_2826	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEC338SC_2827	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_2830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IEC338SC_2831	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEC338SC_2832	COG2890	protein-(glutamine-N5) methyltransferase activity
IEC338SC_2835	COG0583	DNA-binding transcription factor activity
IEC338SC_2838	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEC338SC_2840	COG3658	cytochrome
IEC338SC_2841	COG1215	transferase activity, transferring glycosyl groups
IEC338SC_2842	COG0726	polysaccharide deacetylase
IEC338SC_2842	COG1649	PFAM Uncharacterised BCR, COG1649
IEC338SC_2848	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEC338SC_2849	COG1845	cytochrome c oxidase, subunit III
IEC338SC_2850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IEC338SC_2855	COG0305	Participates in initiation and elongation during chromosome replication
IEC338SC_2856	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEC338SC_2858	COG1305	Transglutaminase-like
IEC338SC_2860	COG2308	Evidence 4 Homologs of previously reported genes of
IEC338SC_2866	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IEC338SC_2868	COG0151	Belongs to the GarS family
IEC338SC_2869	COG1464	Belongs to the NlpA lipoprotein family
IEC338SC_2870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEC338SC_2871	COG2011	ABC-type metal ion transport system permease component
IEC338SC_2872	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_2874	COG1301	dicarboxylic acid transport
IEC338SC_2880	COG1794	racemase activity, acting on amino acids and derivatives
IEC338SC_2883	COG0745	RESPONSE REGULATOR receiver
IEC338SC_2884	COG0642	Histidine kinase
IEC338SC_2885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IEC338SC_2887	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IEC338SC_2895	COG2351	hydroxyisourate hydrolase activity
IEC338SC_2897	COG3008	intermembrane lipid transfer
IEC338SC_2897	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IEC338SC_2898	COG2995	paraquat-inducible protein a
IEC338SC_2900	COG0583	DNA-binding transcription factor activity
IEC338SC_2901	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEC338SC_2906	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IEC338SC_2906	COG0475	glutathione-regulated potassium exporter activity
IEC338SC_2907	COG0786	glutamate:sodium symporter activity
IEC338SC_2908	COG3243	poly(R)-hydroxyalkanoic acid synthase
IEC338SC_2911	COG1278	Cold shock
IEC338SC_2916	COG0515	serine threonine protein kinase
IEC338SC_2916	COG2815	serine threonine protein kinase
IEC338SC_2921	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IEC338SC_2922	COG1610	YqeY-like protein
IEC338SC_2923	COG4783	chaperone-mediated protein folding
IEC338SC_2928	COG1286	toxin biosynthetic process
IEC338SC_2934	COG0778	Nitroreductase
IEC338SC_2936	COG0513	Belongs to the DEAD box helicase family
IEC338SC_2940	COG2363	Small membrane protein
IEC338SC_2945	COG4650	regulator
IEC338SC_2946	COG1234	tRNA 3'-trailer cleavage
IEC338SC_2947	COG1690	Belongs to the RtcB family
IEC338SC_2951	COG2195	Cleaves the N-terminal amino acid of tripeptides
IEC338SC_2953	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IEC338SC_2957	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_2958	COG1301	dicarboxylic acid transport
IEC338SC_2959	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IEC338SC_2960	COG3139	Protein of unknown function (DUF1315)
IEC338SC_2961	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEC338SC_2962	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEC338SC_2964	COG0494	nUDIX hydrolase
IEC338SC_2966	COG0642	Histidine kinase
IEC338SC_2967	COG0745	RESPONSE REGULATOR receiver
IEC338SC_2971	COG1720	tRNA m6t6A37 methyltransferase activity
IEC338SC_2973	COG0384	phenazine biosynthesis protein PhzF
IEC338SC_2974	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEC338SC_2976	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEC338SC_2978	COG4598	ABC transporter
IEC338SC_2979	COG4160	amino acid transport
IEC338SC_2980	COG4215	(ABC) transporter
IEC338SC_2981	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_2983	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_2985	COG1538	Outer membrane efflux protein
IEC338SC_2991	COG1131	(ABC) transporter
IEC338SC_2992	COG0842	Transport permease protein
IEC338SC_2995	COG0772	Belongs to the SEDS family
IEC338SC_2996	COG2951	lytic endotransglycosylase activity
IEC338SC_3001	COG2207	Transcriptional regulator
IEC338SC_3004	COG0052	Belongs to the universal ribosomal protein uS2 family
IEC338SC_3005	COG0024	Methionine aminopeptidase
IEC338SC_3007	COG2223	nitrite transmembrane transporter activity
IEC338SC_3010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEC338SC_3011	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEC338SC_3012	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_3015	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IEC338SC_3016	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IEC338SC_3017	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IEC338SC_3021	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEC338SC_3022	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEC338SC_3023	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEC338SC_3030	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IEC338SC_3033	COG3104	oligopeptide transport
IEC338SC_3035	COG0582	viral genome integration into host DNA
IEC338SC_3055	COG3561	AntA/AntB antirepressor
IEC338SC_3087	COG0305	Participates in initiation and elongation during chromosome replication
IEC338SC_3099	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEC338SC_3105	COG0512	Glutamine amidotransferase of anthranilate synthase
IEC338SC_3108	COG2840	Smr protein MutS2
IEC338SC_3110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IEC338SC_3116	COG3739	integral membrane protein
IEC338SC_3119	COG1169	isochorismate synthase
IEC338SC_3121	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IEC338SC_3126	COG1535	isochorismatase
IEC338SC_3126	COG3433	isochorismatase activity
IEC338SC_3127	COG1021	2,3-dihydroxybenzoate-AMP ligase
IEC338SC_3128	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEC338SC_3130	COG4774	siderophore transport
IEC338SC_3131	COG4607	ABC-type enterochelin transport system periplasmic component
IEC338SC_3132	COG4604	ABC transporter, ATP-binding protein
IEC338SC_3133	COG4605	iron ion homeostasis
IEC338SC_3134	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEC338SC_3136	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEC338SC_3139	COG1741	Belongs to the pirin family
IEC338SC_3140	COG2964	Protein conserved in bacteria
IEC338SC_3145	COG1401	restriction endodeoxyribonuclease activity
IEC338SC_3147	COG2879	small protein
IEC338SC_3148	COG1966	Carbon starvation protein
IEC338SC_3149	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEC338SC_3157	COG1067	ATP-dependent peptidase activity
IEC338SC_3158	COG0583	DNA-binding transcription factor activity
IEC338SC_3163	COG1686	Belongs to the peptidase S11 family
IEC338SC_3164	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IEC338SC_3171	COG0616	signal peptide processing
IEC338SC_3172	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IEC338SC_3174	COG0573	inorganic phosphate transmembrane transporter activity
IEC338SC_3175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IEC338SC_3176	COG1113	amino acid transport
IEC338SC_3177	COG3961	Belongs to the TPP enzyme family
IEC338SC_3178	COG1522	sequence-specific DNA binding
IEC338SC_3180	COG0076	glutamate decarboxylase activity
IEC338SC_3181	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_3184	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEC338SC_3191	COG0352	thiamine-phosphate diphosphorylase activity
IEC338SC_3196	COG0612	Peptidase, M16
IEC338SC_3199	COG0583	DNA-binding transcription factor activity
IEC338SC_3200	COG0477	Major facilitator Superfamily
IEC338SC_3203	COG1187	pseudouridine synthase activity
IEC338SC_3206	COG1686	Belongs to the peptidase S11 family
IEC338SC_3207	COG1252	NADH dehydrogenase
IEC338SC_3209	COG0415	Belongs to the DNA photolyase family
IEC338SC_3212	COG1215	transferase activity, transferring glycosyl groups
IEC338SC_3218	COG2070	2-Nitropropane dioxygenase
IEC338SC_3288	COG2962	Rard protein
IEC338SC_3290	COG0556	nucleotide-excision repair
IEC338SC_3299	COG4221	oxidoreductase activity
IEC338SC_3301	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IEC338SC_3302	COG1381	Involved in DNA repair and RecF pathway recombination
IEC338SC_3304	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEC338SC_3305	COG0571	ribonuclease III activity
IEC338SC_3307	COG0681	Belongs to the peptidase S26 family
IEC338SC_3308	COG0481	GTPase activity
IEC338SC_3310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEC338SC_3314	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEC338SC_3315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IEC338SC_3316	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IEC338SC_3318	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IEC338SC_3319	COG4208	sulfate ABC transporter
IEC338SC_3320	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IEC338SC_3321	COG0583	DNA-binding transcription factor activity
IEC338SC_3322	COG4625	pathogenesis
IEC338SC_3325	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IEC338SC_3328	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IEC338SC_3331	COG1056	cytidyltransferase-related domain
IEC338SC_3331	COG1051	belongs to the nudix hydrolase family
IEC338SC_3332	COG1024	Enoyl-CoA hydratase
IEC338SC_3333	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEC338SC_3335	COG2814	Major facilitator Superfamily
IEC338SC_3337	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEC338SC_3337	COG0047	phosphoribosylformylglycinamidine synthase activity
IEC338SC_3341	COG1473	amidohydrolase
IEC338SC_3342	COG0824	Thioesterase
IEC338SC_3346	COG0823	Involved in the tonB-independent uptake of proteins
IEC338SC_3350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEC338SC_3357	COG0628	permease
IEC338SC_3359	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IEC338SC_3360	COG0596	Alpha beta hydrolase
IEC338SC_3361	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IEC338SC_3361	COG0616	signal peptide processing
IEC338SC_3363	COG2333	competence protein COMEC
IEC338SC_3363	COG0658	competence protein
IEC338SC_3364	COG1136	(ABC) transporter
IEC338SC_3365	COG4591	ABC-type transport system involved in lipoprotein release permease component
IEC338SC_3366	COG0697	spore germination
IEC338SC_3371	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_3377	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IEC338SC_3378	COG1280	lysine exporter protein (LysE YggA)
IEC338SC_3382	COG0019	diaminopimelate decarboxylase activity
IEC338SC_3384	COG1113	amino acid transport
IEC338SC_3385	COG1115	amino acid carrier protein
IEC338SC_3388	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IEC338SC_3391	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IEC338SC_3392	COG0243	molybdopterin cofactor binding
IEC338SC_3393	COG1929	Belongs to the glycerate kinase type-1 family
IEC338SC_3396	COG0778	Nitroreductase
IEC338SC_3399	COG0406	alpha-ribazole phosphatase activity
IEC338SC_3406	COG0789	Transcriptional regulator
IEC338SC_3413	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IEC338SC_3417	COG0741	lytic transglycosylase activity
IEC338SC_3421	COG0584	glycerophosphoryl diester phosphodiesterase
IEC338SC_3427	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IEC338SC_3431	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEC338SC_3432	COG0477	Major facilitator Superfamily
IEC338SC_3434	COG2264	protein methyltransferase activity
IEC338SC_3442	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IEC338SC_3443	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEC338SC_3448	COG0505	Belongs to the CarA family
IEC338SC_3451	COG1309	transcriptional regulator
IEC338SC_3452	COG0251	oxidation-reduction process
IEC338SC_3455	COG0589	response to stress
IEC338SC_3459	COG2843	Capsule synthesis protein
IEC338SC_3462	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IEC338SC_3463	COG1053	succinate dehydrogenase
IEC338SC_3464	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IEC338SC_3465	COG2009	succinate dehydrogenase
IEC338SC_3473	COG2921	Belongs to the UPF0250 family
IEC338SC_3474	COG0321	lipoyl(octanoyl) transferase activity
IEC338SC_3477	COG0531	amino acid
IEC338SC_3480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IEC338SC_3481	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IEC338SC_3481	COG1648	precorrin-2 dehydrogenase activity
IEC338SC_3484	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IEC338SC_3489	COG0671	phosphoesterase, PA-phosphatase related
IEC338SC_3490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEC338SC_3492	COG1538	Outer membrane efflux protein
IEC338SC_3493	COG0393	Putative heavy-metal-binding
IEC338SC_3494	COG0393	Putative heavy-metal-binding
IEC338SC_3496	COG1028	Short-chain dehydrogenase reductase Sdr
IEC338SC_3498	COG0525	valine-tRNA ligase activity
IEC338SC_3503	COG0583	DNA-binding transcription factor activity
IEC338SC_3504	COG0004	ammonium transporteR
IEC338SC_3506	COG0642	Histidine kinase
IEC338SC_3507	COG0745	RESPONSE REGULATOR receiver
IEC338SC_3508	COG2194	sulfuric ester hydrolase activity
IEC338SC_3513	COG1752	Esterase of the alpha-beta hydrolase superfamily
IEC338SC_3516	COG2315	Protein conserved in bacteria
IEC338SC_3517	COG0142	geranyltranstransferase activity
IEC338SC_3518	COG2828	Protein conserved in bacteria
IEC338SC_3519	COG1113	amino acid transport
IEC338SC_3520	COG2816	NAD+ diphosphatase activity
IEC338SC_3521	COG3046	protein related to deoxyribodipyrimidine photolyase
IEC338SC_3532	COG2207	Transcriptional regulator
IEC338SC_3537	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEC338SC_3541	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IEC338SC_3543	COG1530	ribonuclease E activity
IEC338SC_3544	COG0424	maF-like protein
IEC338SC_3545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IEC338SC_3546	COG1792	Involved in formation and maintenance of cell shape
IEC338SC_3547	COG1077	Cell shape determining protein MreB Mrl
IEC338SC_3548	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEC338SC_3550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEC338SC_3556	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IEC338SC_3557	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEC338SC_3558	COG1752	Esterase of the alpha-beta hydrolase superfamily
IEC338SC_3559	COG1115	amino acid carrier protein
IEC338SC_3562	COG2814	Major facilitator Superfamily
IEC338SC_3563	COG1289	transmembrane transporter activity
IEC338SC_3565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEC338SC_3573	COG1376	ErfK ybiS ycfS ynhG family protein
IEC338SC_3574	COG2832	Protein of unknown function (DUF454)
IEC338SC_3576	COG5510	response to toxic substance
IEC338SC_3581	COG0840	transmembrane signaling receptor activity
IEC338SC_3589	COG3422	double-strand break repair
IEC338SC_3590	COG2824	Alkylphosphonate utilization operon protein PhnA
IEC338SC_3591	COG3189	MarR family transcriptional regulator
IEC338SC_3593	COG0354	folic acid binding
IEC338SC_3594	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEC338SC_3596	COG0679	Auxin Efflux Carrier
IEC338SC_3597	COG1902	pentaerythritol trinitrate reductase activity
IEC338SC_3598	COG4772	TonB-dependent receptor
IEC338SC_3599	COG2094	Belongs to the DNA glycosylase MPG family
IEC338SC_3602	COG4580	involved in the transport of maltose and maltodextrins
IEC338SC_3606	COG2233	PERMEase
IEC338SC_3608	COG0833	amino acid
IEC338SC_3609	COG1690	Belongs to the RtcB family
IEC338SC_3611	COG2885	chlorophyll binding
IEC338SC_3611	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IEC338SC_3613	COG0183	Belongs to the thiolase family
IEC338SC_3617	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEC338SC_3621	COG2207	Transcriptional regulator
IEC338SC_3622	COG0183	Belongs to the thiolase family
IEC338SC_3626	COG2153	protein acetylation
IEC338SC_3628	COG1272	protein, Hemolysin III
IEC338SC_3629	COG0477	Major facilitator Superfamily
IEC338SC_3632	COG0450	alkyl hydroperoxide reductase
IEC338SC_3636	COG0285	dihydrofolate synthase activity
IEC338SC_3643	COG0133	tryptophan synthase activity
IEC338SC_3646	COG2096	Adenosyltransferase
IEC338SC_3650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IEC338SC_3652	COG0745	RESPONSE REGULATOR receiver
IEC338SC_3653	COG2205	protein histidine kinase activity
IEC338SC_3655	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_3656	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_3657	COG0583	DNA-binding transcription factor activity
IEC338SC_3658	COG0625	glutathione transferase activity
IEC338SC_3670	COG0438	transferase activity, transferring glycosyl groups
IEC338SC_3671	COG0463	Glycosyl transferase, family 2
IEC338SC_3672	COG0726	polysaccharide deacetylase
IEC338SC_3676	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IEC338SC_3677	COG0784	Response regulator, receiver
IEC338SC_3677	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IEC338SC_3677	COG2198	Histidine kinase
IEC338SC_3677	COG2205	protein histidine kinase activity
IEC338SC_3687	COG1862	Preprotein translocase
IEC338SC_3689	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEC338SC_3690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEC338SC_3692	COG3781	membrane
IEC338SC_3695	COG2350	Protein conserved in bacteria
IEC338SC_3702	COG1607	acyl-coa hydrolase
IEC338SC_3705	COG3453	Protein conserved in bacteria
IEC338SC_3705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IEC338SC_3715	COG2199	diguanylate cyclase activity
IEC338SC_3716	COG2885	chlorophyll binding
IEC338SC_3716	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IEC338SC_3717	COG1408	metallophosphoesterase
IEC338SC_3718	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEC338SC_3720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEC338SC_3724	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IEC338SC_3725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IEC338SC_3726	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IEC338SC_3727	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEC338SC_3728	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IEC338SC_3730	COG2969	positive regulation of protein catabolic process
IEC338SC_3734	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_3735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IEC338SC_3738	COG1309	transcriptional regulator
IEC338SC_3739	COG1960	acyl-CoA dehydrogenase activity
IEC338SC_3747	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEC338SC_3752	COG0583	DNA-binding transcription factor activity
IEC338SC_3758	COG5549	protein import
IEC338SC_3758	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEC338SC_3760	COG2951	lytic endotransglycosylase activity
IEC338SC_3761	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEC338SC_3765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IEC338SC_3767	COG0671	phosphoesterase, PA-phosphatase related
IEC338SC_3768	COG0861	Integral membrane protein TerC family
IEC338SC_3770	COG0754	glutathionylspermidine amidase activity
IEC338SC_3772	COG0402	S-adenosylhomocysteine deaminase activity
IEC338SC_3776	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IEC338SC_3777	COG1230	cation diffusion facilitator family transporter
IEC338SC_3780	COG0706	membrane insertase activity
IEC338SC_3783	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IEC338SC_p3803	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IEC338SC_p3804	COG4456	Virulence-associated protein
IEC338SC_p3807	COG0515	serine threonine protein kinase
IEC338SC_p3807	COG3064	Membrane
IEC338SC_p3807	COG4991	sh3 domain protein