locus-tag class description DLK06_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DLK06_00020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DLK06_00035 ENOG4105C5H ABC transporter DLK06_00040 ENOG4108821 RND type efflux pump DLK06_00045 ENOG4108821 RND type efflux pump DLK06_00050 ENOG4108821 RND type efflux pump DLK06_00060 ENOG4105D74 hydrolase DLK06_00065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) DLK06_00070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DLK06_00115 ENOG4105C8J )-transporter DLK06_00125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DLK06_00155 ENOG4105C2W permease DLK06_00165 ENOG4108IG5 Transcriptional regulator DLK06_00170 ENOG4105DJY efflux transporter, rnd family, mfp subunit DLK06_00205 ENOG4105F27 Major Facilitator DLK06_00210 ENOG4105CV8 reductase DLK06_00215 ENOG4105HEI LysR family (Transcriptional regulator DLK06_00235 ENOG4105DQ4 alcohol dehydrogenase DLK06_00240 ENOG4108R3E Dna-3-methyladenine glycosylase i DLK06_00255 ENOG4105CEN a g-specific adenine glycosylase DLK06_00275 ENOG4108ZZ3 UPF0260 protein DLK06_00280 ENOG4105D8V Glucose sorbosone dehydrogenase DLK06_00285 ENOG4105D1H recombination factor protein RarA DLK06_00290 ENOG4105S64 Formate nitrite transporter DLK06_00310 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DLK06_00320 ENOG4105C09 Bile acid DLK06_00340 ENOG4105EWC Purine nucleoside phosphorylase DLK06_00355 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) DLK06_00360 ENOG4108RXX maleylacetoacetate isomerase DLK06_00370 ENOG4105C85 amino acid DLK06_00380 ENOG4105CKI cobalamin synthesis protein DLK06_00390 ENOG4105CZE histidine utilization repressor DLK06_00395 ENOG41090B9 response to stress DLK06_00420 ENOG41088SP formiminoglutamate hydrolase DLK06_00430 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 DLK06_00435 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DLK06_00455 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DLK06_00465 ENOG4108ZAI phosphatidylglycerophosphatase a DLK06_00470 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) DLK06_00485 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DLK06_00525 ENOG4105KHC sulfurtransferase DLK06_00550 ENOG4105BZU Histidine kinase DLK06_00555 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DLK06_00570 ENOG4107QJQ Mate efflux family protein DLK06_00575 ENOG4105CHM Aminotransferase DLK06_00580 ENOG4106BRA Membrane DLK06_00595 ENOG4105D9M gamma-glutamylcysteine synthetase DLK06_00610 ENOG4105NVB glycoside hydrolase, family 19 DLK06_00625 ENOG4105IPS esterase DLK06_00630 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DLK06_00635 ENOG4108Z2U ureidoglycolate hydrolase DLK06_00645 ENOG41061H0 Monooxygenase DLK06_00660 ENOG41084YZ Hydrolase DLK06_00690 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) DLK06_00695 ENOG4105BZU Histidine kinase DLK06_00710 ENOG4105KUZ arsenate reductase DLK06_00715 ENOG4105CGK Exodeoxyribonuclease III DLK06_00740 ENOG4105D7Z glutathione synthase DLK06_00760 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) DLK06_00765 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DLK06_00770 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DLK06_00785 ENOG41063SB peptidase DLK06_00790 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) DLK06_00795 ENOG4107QSN dihydrolipoamide acetyltransferase DLK06_00810 ENOG4105E0K tonB-dependent siderophore receptor DLK06_00825 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DLK06_00840 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DLK06_00860 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DLK06_00865 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase DLK06_00875 ENOG4105D64 Mechanosensitive ion channel DLK06_00885 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DLK06_00890 ENOG4108W2Y isochorismatase DLK06_00900 ENOG4105FBW Monooxygenase DLK06_00905 ENOG4108UZX fmn reductase DLK06_00920 ENOG4105BZU Histidine kinase DLK06_00925 ENOG41062QD Membrane DLK06_00930 ENOG4107QN1 sodium solute DLK06_00940 ENOG4105C94 Transporter DLK06_00950 ENOG4105BZU Histidine kinase DLK06_00955 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DLK06_00960 ENOG4108WUH Transcriptional regulator, TetR family DLK06_00975 ENOG4105RA2 Membrane DLK06_00980 ENOG4105DWF phosphomethylpyrimidine kinase DLK06_00990 ENOG4107RDB Major Facilitator DLK06_00995 ENOG4108UUM single-stranded DNA-binding protein DLK06_01005 ENOG4108UMN azlc family DLK06_01025 ENOG4108JPW Aminotransferase DLK06_01030 ENOG4105C26 Dehydrogenase DLK06_01040 ENOG4105CHJ isochorismatase hydrolase DLK06_01045 ENOG4105EUB pirin domain protein DLK06_01130 ENOG41082JN Transcriptional regulator DLK06_01150 ENOG4105D94 Major Facilitator Superfamily DLK06_01155 ENOG4106NZI LysR family Transcriptional regulator DLK06_01175 ENOG4105CPC Aldo Keto reductase DLK06_01180 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) DLK06_01225 ENOG4105KVH Transcriptional regulator DLK06_01235 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein DLK06_01280 ENOG4108V1U phospholipid-binding protein DLK06_01285 ENOG4108TSE Transferase DLK06_01290 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain DLK06_01295 ENOG4108UQN AraC family transcriptional regulator DLK06_01355 ENOG4105CUV Homoserine Kinase DLK06_01370 ENOG41061CK Antibiotic biosynthesis monooxygenase DLK06_01385 ENOG4105BZ1 (ABC) transporter DLK06_01395 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) DLK06_01405 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DLK06_01435 ENOG4105CYC Transferase DLK06_01445 ENOG4105E0F Histidine kinase DLK06_01450 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DLK06_01460 ENOG4105CHH sulfate transporter DLK06_01465 ENOG4105PDP Short chain dehydrogenase DLK06_01475 ENOG4105C5H ABC transporter DLK06_01560 ENOG4108IQI permease DLK06_01585 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein DLK06_01600 ENOG4105CJN penicillin-binding protein DLK06_01605 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DLK06_01610 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) DLK06_01625 ENOG4105DHI Methyltransferase DLK06_01630 ENOG4108JQC penicillin-binding protein 1A DLK06_01655 ENOG4105E4G Type IV pilus DLK06_01675 ENOG4105CBC glutamate synthase DLK06_01680 ENOG4105BZ8 glutamate synthase DLK06_01690 ENOG4108V0P LemA family DLK06_01695 ENOG4105HA9 of methanol dehydrogenase type DLK06_01715 ENOG4108YSG O-Antigen polymerase DLK06_01720 ENOG4108UQY Iron-storage protein DLK06_01735 ENOG4105KME endoribonuclease L-psp DLK06_01740 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DLK06_01755 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) DLK06_01805 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) DLK06_01815 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) DLK06_01820 ENOG4107IFA Lipase (EC 3.1.1.3) DLK06_01825 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) DLK06_01830 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DLK06_01845 ENOG4107AQZ Membrane DLK06_01850 ENOG4107AQZ Membrane DLK06_01855 ENOG4108JQ1 Dehydrogenase DLK06_01860 ENOG4105CQB FAD linked oxidase domain protein DLK06_01870 ENOG4105VRH Antibiotic biosynthesis monooxygenase DLK06_01875 ENOG4105NF4 modulator of drug activity DLK06_01885 ENOG4107QF7 multi-drug DLK06_01890 ENOG4105EM2 membrane DLK06_01895 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DLK06_01900 ENOG4105IPI Membrane DLK06_01905 ENOG4107SKI cobyrinic Acid a,c-diamide synthase DLK06_01935 ENOG4108IQI permease DLK06_01940 ENOG4105D82 Glutamate dehydrogenase DLK06_01945 ENOG4105C8Y Acetylornithine aminotransferase DLK06_01955 ENOG4105C26 Dehydrogenase DLK06_01980 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin DLK06_02025 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit DLK06_02055 ENOG41067S9 phage shock protein C, PspC DLK06_02065 ENOG4105CSU acyl-Coa dehydrogenase DLK06_02080 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) DLK06_02095 ENOG4105ECY inositol monophosphatase DLK06_02100 ENOG4105C1J atp-dependent rna helicase DLK06_02110 ENOG4105DHJ ABC, transporter DLK06_02115 ENOG4105CY3 ABC transporter, permease DLK06_02125 ENOG4105E3I toluene tolerance DLK06_02135 ENOG4105D7N magnesium and cobalt transport protein CorA DLK06_02140 ENOG4108URH decarboxylase DLK06_02150 ENOG4105MJ2 Competence protein DLK06_02155 ENOG4105CB5 ATP-dependent DNA helicase recG DLK06_02175 ENOG4105C29 acyl-CoA thioesterase DLK06_02180 ENOG4105CK2 sodium dicarboxylate symporter DLK06_02195 ENOG4105KPV Transcriptional regulator DLK06_02210 ENOG4105D7A ATP-binding protein DLK06_02215 ENOG4105C28 cystathionine DLK06_02220 ENOG41089BK Glutamine amido-transferase DLK06_02230 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) DLK06_02235 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) DLK06_02330 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DLK06_02335 ENOG41067V7 50S ribosomal protein L36 DLK06_02345 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) DLK06_02370 ENOG4105C1G acyl-Coa dehydrogenase DLK06_02405 ENOG4105VKU nucleicacid-binding protein DLK06_02410 ENOG4105DGW oligopeptidase A DLK06_02415 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DLK06_02465 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase DLK06_02470 ENOG4107S2Z UPF0761 membrane protein DLK06_02475 ENOG4105CS1 NAD(P)H quinone oxidoreductase DLK06_02505 ENOG4105C9A Phoh family DLK06_02515 ENOG4105E4C Lytic transglycosylase catalytic DLK06_02545 ENOG4105D6S protein involved in catabolism of external DNA DLK06_02550 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DLK06_02595 ENOG4105C1G acyl-Coa dehydrogenase DLK06_02600 ENOG4108RZE Tetr family transcriptional regulator DLK06_02615 ENOG4107QX3 carboxylase DLK06_02620 ENOG4105C1G acyl-Coa dehydrogenase DLK06_02660 ENOG4105KB2 stringent starvation protein b DLK06_02665 ENOG4107MKT Stringent starvation protein a DLK06_02670 ENOG4108UJD 30S ribosomal protein S9 DLK06_02675 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) DLK06_02680 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) DLK06_02685 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DLK06_02690 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) DLK06_02710 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DLK06_02720 ENOG4107RZC phospholipase d DLK06_02735 ENOG4108KHX Diguanylate cyclase DLK06_02740 ENOG4108WS1 DLK06_02790 ENOG4107QPB Beta-lactamase domain protein DLK06_02825 ENOG4105NAU thioesterase Superfamily protein DLK06_02870 ENOG4105DB7 PHP domain protein DLK06_02875 ENOG4105FFC UPF0187 protein DLK06_02885 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DLK06_02890 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DLK06_02895 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DLK06_02900 ENOG4105VIE preprotein translocase, subunit YajC DLK06_02920 ENOG4105BZU Histidine kinase DLK06_02925 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) DLK06_02930 ENOG4105CM2 brancheD-chain amino acid aminotransferase DLK06_02940 ENOG4107BJW polysaccharide deacetylase DLK06_02955 ENOG4107S6X Glycosyl transferase, family 2 DLK06_02980 ENOG4105UGU tonB-dependent Receptor DLK06_03005 ENOG4108K3A Glutathione S-transferase DLK06_03010 ENOG4105EQ2 LysR family Transcriptional regulator DLK06_03015 ENOG4105CSU acyl-Coa dehydrogenase DLK06_03020 ENOG4105CSU acyl-Coa dehydrogenase DLK06_03030 ENOG4105EB3 Histidine kinase DLK06_03035 ENOG4105E3W Two component transcriptional regulator (Winged helix family DLK06_03050 ENOG4105CNG UPF0061 protein DLK06_03070 ENOG4108WBT adenosyltransferase DLK06_03085 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DLK06_03120 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DLK06_03140 ENOG4105D3R alkyl hydroperoxide reductase DLK06_03155 ENOG4105CSH Transporter DLK06_03160 ENOG4108UT2 hemolysin iii DLK06_03170 ENOG41082BV acetyltransferase DLK06_03190 ENOG4105CHU acetyl-coa acetyltransferase DLK06_03195 ENOG4108R6W Transcriptional regulator, ARAC family DLK06_03205 ENOG4105TW1 Carbohydrate-selective porin OprB DLK06_03210 ENOG4105DZG Dehydrogenase DLK06_03215 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DLK06_03235 ENOG4105CHU acetyl-coa acetyltransferase DLK06_03240 ENOG4105X0D Fimbrial protein DLK06_03245 ENOG4108WHA ompa motb domain protein DLK06_03250 ENOG4105E0Y RtcB Protein DLK06_03255 ENOG4108IQI permease DLK06_03265 ENOG4105C2W permease DLK06_03300 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DLK06_03310 ENOG4108VX5 3-methyladenine DNA glycosylase DLK06_03320 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DLK06_03325 ENOG4108N2Y auxin Efflux DLK06_03335 ENOG4105T95 Thiol disulfide interChange protein DLK06_03340 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) DLK06_03360 ENOG4105C2W permease DLK06_03365 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) DLK06_03370 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) DLK06_03375 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) DLK06_03380 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) DLK06_03385 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) DLK06_03390 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) DLK06_03395 ENOG4105K78 MarR family Transcriptional regulator DLK06_03400 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DLK06_03405 ENOG4105KWI UPF0339 protein DLK06_03430 ENOG4108UNF response regulator DLK06_03435 ENOG4105M3Z response regulator DLK06_03440 ENOG4108ZGA chew protein DLK06_03450 ENOG4105C8Q Methyl-accepting chemotaxis DLK06_03455 ENOG4105CBS Chea signal transduction histidine kinase DLK06_03470 ENOG4106HKS Entericidin EcnA/B family DLK06_03480 ENOG4105WD1 Membrane DLK06_03485 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein DLK06_03525 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) DLK06_03535 ENOG4105EM2 membrane DLK06_03540 ENOG4105C2C drug resistance transporter, Bcr CflA DLK06_03560 ENOG4105BZG amino acid carrier protein DLK06_03565 ENOG4105D78 K07001 NTE family protein DLK06_03570 ENOG4105C7B Threonine dehydratase DLK06_03580 ENOG4105C9K Endothelin-converting enzyme 1 DLK06_03605 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DLK06_03615 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DLK06_03620 ENOG4105DFF Rod shape-determining protein mreb DLK06_03625 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DLK06_03630 ENOG4105VQ7 Rod shape-determining protein MreD DLK06_03635 ENOG4108Z03 MAF-like protein DLK06_03640 ENOG4105C03 ribonuclease DLK06_03650 ENOG4105D8T Acyltransferase DLK06_03660 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein DLK06_03670 ENOG4108X0B nad(p)h dehydrogenase (quinone) DLK06_03695 ENOG4105CF7 AraC family transcriptional regulator DLK06_03780 ENOG4105F9F transposase DLK06_03795 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase DLK06_03800 ENOG4105EPC oxidoreductase DLK06_03805 ENOG4105VF7 tolerance protein DLK06_03810 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) DLK06_03835 ENOG4105F9F transposase DLK06_03850 ENOG4105CDU Replicative dna helicase DLK06_03905 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein DLK06_03910 ENOG4105E09 nadh pyrophosphatase DLK06_03915 ENOG4105C85 amino acid DLK06_03920 ENOG4105C7F AcnD-accessory protein PrpF DLK06_03925 ENOG4105CTB Polyprenyl synthetase DLK06_03930 ENOG4105MSB protein, conserved in bacteria DLK06_03945 ENOG4105D78 K07001 NTE family protein DLK06_03985 ENOG4105DIJ Phosphoethanolamine transferase DLK06_03990 ENOG4105XJC Two component transcriptional regulator (Winged helix family DLK06_03995 ENOG4105DHQ Histidine kinase DLK06_04010 ENOG4108M0I Transcriptional regulator DLK06_04030 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DLK06_04050 ENOG41082CH UPF0145 protein DLK06_04055 ENOG4105K8R UPF0145 protein DLK06_04060 ENOG4105ENJ RND efflux system, outer membrane lipoprotein DLK06_04065 ENOG4105BZS acriflavin resistance protein DLK06_04070 ENOG4105C1P efflux transporter, rnd family, mfp subunit DLK06_04075 ENOG410841Q phosphoesterase PA-phosphatase related protein DLK06_04100 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) DLK06_04115 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DLK06_04120 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DLK06_04170 ENOG4105CUB amino acid DLK06_04185 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) DLK06_04190 ENOG41084BA UPF0250 protein DLK06_04195 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DLK06_04235 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit DLK06_04240 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein DLK06_04250 ENOG4105E33 succinate dehydrogenase DLK06_04265 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 DLK06_04270 ENOG4105C7S Dehydrogenase DLK06_04275 ENOG4107QN2 dihydrolipoyl dehydrogenase DLK06_04285 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DLK06_04310 ENOG4105CKW Inner membrane protein yedI DLK06_04315 ENOG4105CGZ zinc metallopeptidase DLK06_04320 ENOG4105EEQ Na H antiporter DLK06_04335 ENOG4105PNM synthesis protein DLK06_04355 ENOG41080TK Universal stress protein DLK06_04365 ENOG4108UQ8 endoribonuclease L-psp DLK06_04370 ENOG4108Q5F Tetr family transcriptional regulator DLK06_04380 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain DLK06_04385 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DLK06_04410 ENOG4105HBR Rna-binding protein DLK06_04420 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DLK06_04425 ENOG4105EEI dihydropteroate synthase DLK06_04445 ENOG4105DGI Alkaline phosphatase DLK06_04480 ENOG4105CSH Transporter DLK06_04485 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) DLK06_04490 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DLK06_04505 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) DLK06_04545 ENOG41076J9 exonuclease VIII DLK06_04560 ENOG41067QW Transcriptional regulator DLK06_04740 ENOG4105DFP Integrase DLK06_04745 ENOG41080IJ Diacylglycerol kinase DLK06_04755 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase DLK06_04760 ENOG4105BZS acriflavin resistance protein DLK06_04775 ENOG4105E4C Lytic transglycosylase catalytic DLK06_04800 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DLK06_04805 ENOG4108RRZ Transcription elongation factor GreB DLK06_04815 ENOG4105D01 (LipO)protein DLK06_04845 ENOG4105C1P efflux transporter, rnd family, mfp subunit DLK06_04850 ENOG4105BZS acriflavin resistance protein DLK06_04860 ENOG4108W6C Dehydrogenase DLK06_04895 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit DLK06_04900 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DLK06_04915 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) DLK06_04925 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DLK06_04930 ENOG4105BZG amino acid carrier protein DLK06_04935 ENOG4105C85 amino acid DLK06_04945 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DLK06_04955 ENOG4105N14 lysine exporter protein LysE YggA DLK06_04960 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DLK06_04965 ENOG4105BZJ Electron transfer flavoprotein DLK06_04970 ENOG4105C10 Electron transfer flavoprotein DLK06_04975 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DLK06_04990 ENOG4107KET secretion protein, HlyD family DLK06_05020 ENOG4105D60 lipoprotein releasing system transmembrane protein DLK06_05025 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DLK06_05030 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 DLK06_05040 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) DLK06_05045 ENOG4107R6F Alpha Beta Hydrolase Fold protein DLK06_05050 ENOG4108V3E phosphoribosylglycinamide formyltransferase DLK06_05060 ENOG4105C02 permease DLK06_05130 ENOG4105KCK Peptidoglycan-associated lipoprotein DLK06_05135 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) DLK06_05145 ENOG4105M8F Biopolymer transport protein exbD tolR DLK06_05150 ENOG4105E02 MotA TolQ exbB proton channel DLK06_05155 ENOG4107YD3 Thioesterase DLK06_05160 ENOG4105CH2 amidohydrolase DLK06_05180 ENOG4108ETH Formylglycinamide ribotide synthetase DLK06_05185 ENOG4105C2C drug resistance transporter, Bcr CflA DLK06_05190 ENOG4105EGD dinuclear metal center protein, YbgI family DLK06_05195 ENOG4108UKI Enoyl-CoA hydratase DLK06_05215 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DLK06_05230 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) DLK06_05235 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DLK06_05250 ENOG4107R11 Transcriptional regulator DLK06_05255 ENOG4108IJ6 ABC transporter DLK06_05265 ENOG4108I5D sulfate abc transporter DLK06_05275 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein DLK06_05280 ENOG4105YAZ 4-amino-4-deoxychorismate lyase DLK06_05285 ENOG4105HHA aminodeoxychorismate lyase DLK06_05300 ENOG4108IYU L-aspartate oxidase DLK06_05305 ENOG4105C0H protease DLK06_05320 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) DLK06_05325 ENOG4105C3F Signal peptidase i DLK06_05335 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) DLK06_05340 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DLK06_05350 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) DLK06_05355 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) DLK06_05360 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase DLK06_05365 ENOG4105EMU Dehydrogenase DLK06_05405 ENOG4105BZU Histidine kinase DLK06_05415 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DLK06_05425 ENOG4105DTR rard protein DLK06_05460 ENOG4107QS8 (LipO)protein DLK06_05465 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DLK06_05470 ENOG4105EA8 2-Nitropropane dioxygenase DLK06_05485 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DLK06_05500 ENOG4107R8N Glycosyl transferase, family 2 DLK06_05515 ENOG4105CVP deoxyribo-dipyrimidine photolyase DLK06_05520 ENOG4108YZY peptidylprolyl cis-trans isomerase DLK06_05525 ENOG4105CEP NADH dehydrogenase DLK06_05530 ENOG4105DZ1 carboxypeptidase DLK06_05540 ENOG4105E9K Isocitrate dehydrogenase DLK06_05545 ENOG4108R99 pseudouridine synthase DLK06_05555 ENOG4105CBP Major Facilitator DLK06_05560 ENOG4105EGI Transcriptional regulator DLK06_05565 ENOG4108ETY sodium dicarboxylate symporter DLK06_05570 ENOG4105JAB phenazine biosynthesis protein, phzf family DLK06_05600 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DLK06_05615 ENOG4105D3G Pseudouridine synthase DLK06_05620 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) DLK06_05635 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DLK06_05650 ENOG4108JPW Aminotransferase DLK06_05655 ENOG4105DY8 decarboxylase DLK06_05665 ENOG4105F7P transcriptional regulator AsnC family DLK06_05670 ENOG4107RA9 decarboxylase DLK06_05675 ENOG4105C85 amino acid DLK06_05680 ENOG4105CVA phosphate DLK06_05685 ENOG4105C8U phosphate abc transporter DLK06_05695 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DLK06_05700 ENOG4105ERU peptidase DLK06_05715 ENOG4107QTF adenylosuccinate lyase DLK06_05740 ENOG4108Z0R Transferase DLK06_05745 ENOG4105DZ1 carboxypeptidase DLK06_05765 ENOG4108K5P (LipO)protein DLK06_05770 ENOG4105EJC lysr family transcriptional regulator DLK06_05775 ENOG4105DAN ATP-dependent protease DLK06_05780 ENOG4105EYM Major Facilitator superfamily DLK06_05790 ENOG4105DHU Bile acid DLK06_05810 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DLK06_05815 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) DLK06_05820 ENOG4105D22 carbon starvation protein DLK06_05825 ENOG4105VCD cytoplasmic protein DLK06_05875 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DLK06_05885 ENOG4105C2I pirin domain protein DLK06_05900 ENOG4105CEY Amp-dependent synthetase and ligase DLK06_05915 ENOG4108IPW abc transporter atp-binding protein DLK06_05935 ENOG4105C0W non-ribosomal peptide synthetase DLK06_05940 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase DLK06_05945 ENOG4105WQI isochorismatase DLK06_05960 ENOG4105BZ1 (ABC) transporter DLK06_05965 ENOG4105BZ1 (ABC) transporter DLK06_05980 ENOG4105E4F Isochorismate synthase DLK06_06000 ENOG4105NX3 Membrane DLK06_06020 ENOG4105EUJ GTP cyclohydrolase i DLK06_06030 ENOG4105C7W Xanthine dehydrogenase DLK06_06040 ENOG4108DG9 Smr protein MutS2 DLK06_06060 ENOG4105CD8 aminopeptidase N DLK06_06065 ENOG4105DDQ anthranilate synthase DLK06_06075 ENOG4105DUX Transporter DLK06_06080 ENOG4105C5F glutamine synthetase DLK06_06090 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) DLK06_06125 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DLK06_06130 ENOG4107QNR UPF0135 protein DLK06_06135 ENOG4105C0H protease DLK06_06145 ENOG4105C6K Malic enzyme DLK06_06150 ENOG4105BZU Histidine kinase DLK06_06155 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DLK06_06160 ENOG4105SYT Methylenetetrahydrofolate reductase DLK06_06165 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) DLK06_06180 ENOG4107QPN acyl-Coa dehydrogenase DLK06_06185 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DLK06_06190 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) DLK06_06200 ENOG4107RNU major facilitator superfamily MFS_1 DLK06_06210 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DLK06_06215 ENOG4105CE9 30S ribosomal protein S2 DLK06_06255 ENOG4105CVE Lytic murein transglycosylase DLK06_06260 ENOG4105CNI cell division protein FtsW DLK06_06275 ENOG4105E3A (ABC) transporter DLK06_06280 ENOG4105DA5 (ABC) transporter DLK06_06345 ENOG4105ENJ RND efflux system, outer membrane lipoprotein DLK06_06355 ENOG4105ENT Efflux transporter rnd family, mfp subunit DLK06_06365 ENOG4105E89 ABC transporter DLK06_06370 ENOG4105DSP amino acid AbC transporter DLK06_06375 ENOG4106YG3 ABC transporter DLK06_06380 ENOG4108JEH abc transporter atp-binding protein DLK06_06390 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DLK06_06395 ENOG4105CFP Peptidase U32 DLK06_06400 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DLK06_06405 ENOG4105JAB phenazine biosynthesis protein, phzf family DLK06_06410 ENOG4105DP0 ferredoxin-NADP reductase DLK06_06415 ENOG4108R96 Methyltransferase, YaeB family DLK06_06425 ENOG4107QHF type ii secretion system protein e DLK06_06435 ENOG4105XJC Two component transcriptional regulator (Winged helix family DLK06_06440 ENOG4105DHQ Histidine kinase DLK06_06450 ENOG4105M6F mutator MutT protein DLK06_06460 ENOG4105BZ4 penicillin-binding protein DLK06_06465 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DLK06_06470 ENOG4105VUT cytoplasmic protein DLK06_06475 ENOG4108I0Q anthranilate phosphoribosyltransferase DLK06_06485 ENOG4105CK2 sodium dicarboxylate symporter DLK06_06490 ENOG4105C1G acyl-Coa dehydrogenase DLK06_06500 ENOG4105CQC Prephenate dehydratase DLK06_06505 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase DLK06_06515 ENOG4105CIN aminoacyl-histidine dipeptidase DLK06_06535 ENOG4105E0Y RtcB Protein DLK06_06540 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DLK06_06545 ENOG4105CYB regulatoR DLK06_06575 ENOG4105M08 Membrane DLK06_06580 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DLK06_06590 ENOG4105VEQ Cold shock protein DLK06_06595 ENOG4105C1J atp-dependent rna helicase DLK06_06605 ENOG41069NU Nitroreductase DLK06_06640 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase DLK06_06655 ENOG4105C5I Dehydrogenase DLK06_06660 ENOG4105ERG peptidase m48, ste24p DLK06_06665 ENOG4105KTH gatB Yqey DLK06_06670 ENOG4105VCC 30S ribosomal protein S21 DLK06_06695 ENOG4105D9P serine threonine protein kinase DLK06_06720 ENOG4105VEQ Cold shock protein DLK06_06740 ENOG4105D6U Sodium Glutamate Symporter DLK06_06745 ENOG4105CKD glutathione-regulated potassium-efflux system protein DLK06_06820 ENOG4105R8C Transcriptional regulator DLK06_06825 ENOG4105CEB Aspartate aminotransferase DLK06_06840 ENOG4105F1S paraquat-inducible protein a DLK06_06845 ENOG4105DY2 Paraquat-inducible protein b DLK06_06855 ENOG4105VT2 5-hydroxyisourate hydrolase DLK06_06895 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DLK06_06905 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DLK06_06910 ENOG4105DHQ Histidine kinase DLK06_06915 ENOG4105ETX regulatoR DLK06_06940 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DLK06_06945 ENOG4105E2B Taurine dioxygenase DLK06_06955 ENOG4105F27 Major Facilitator DLK06_06970 ENOG4105HMI Membrane DLK06_07020 ENOG4105CK2 sodium dicarboxylate symporter DLK06_07030 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DLK06_07035 ENOG4108UMI ABC transporter, permease DLK06_07040 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DLK06_07045 ENOG4105D01 (LipO)protein DLK06_07050 ENOG4105C12 Phosphoribosylglycinamide synthetase DLK06_07060 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) DLK06_07110 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DLK06_07115 ENOG4105CDU Replicative dna helicase DLK06_07140 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) DLK06_07145 ENOG4105CCU oxidase (Subunit III) DLK06_07150 ENOG4105BZ9 Cytochrome C oxidase, subunit I DLK06_07155 ENOG4105E2S oxidase) subunit II DLK06_07180 ENOG4107BJW polysaccharide deacetylase DLK06_07185 ENOG4105CND Glycosyl transferase, family 2 DLK06_07190 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD DLK06_07200 ENOG4105DEN Luciferase family DLK06_07220 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DLK06_07225 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DLK06_07230 ENOG4105GVF (ABC) transporter DLK06_07245 ENOG4105C1G acyl-Coa dehydrogenase DLK06_07250 ENOG4108MEJ flavin reductase domain protein DLK06_07265 ENOG4105KRF dihydroneopterin aldolase DLK06_07275 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DLK06_07280 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DLK06_07290 ENOG4105C08 Histidine kinase DLK06_07295 ENOG4105EEX Two component transcriptional regulator (Winged helix family DLK06_07300 ENOG4105CFQ glutamine synthetase DLK06_07315 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) DLK06_07320 ENOG4105CFU surface antigen DLK06_07345 ENOG4107QIJ Aconitate hydratase 2 DLK06_07355 ENOG4105EYW Ion transport protein DLK06_07360 ENOG4105F27 Major Facilitator DLK06_07465 ENOG4108QUU Morphogenesis Protein DLK06_07470 ENOG4105QIB mu-like prophage Flumu protein gp29 DLK06_07485 ENOG4105CF2 Mu-like prophage FluMu protein GP28 DLK06_07570 ENOG4105K70 DNA-binding protein DLK06_07620 ENOG4105DZ2 Transcriptional regulator DLK06_07635 ENOG4105I08 Pseudouridine synthase DLK06_07655 ENOG4105K8N protein family UPF0079, ATPase DLK06_07660 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) DLK06_07670 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DLK06_07675 ENOG4108TZV Membrane DLK06_07680 ENOG4108RCM Nitroreductase DLK06_07690 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) DLK06_07700 ENOG4105CX6 glutaminyL-tRNA synthetase DLK06_07710 ENOG4105F9F transposase DLK06_07720 ENOG4107FQ9 ethanolamine ammonia-lyase DLK06_07725 ENOG4105CPD ethanolamine ammonia-lyase DLK06_07730 ENOG4105CUB amino acid DLK06_07740 ENOG4107RR1 TRANSCRIPTIONal DLK06_07750 ENOG4105C0A alcohol dehydrogenase DLK06_07755 ENOG4107QUV Domain protein DLK06_07780 ENOG4105CD8 aminopeptidase N DLK06_07795 ENOG4108D1K outer membrane usher protein DLK06_07820 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) DLK06_07840 ENOG4105GAV receptor DLK06_07845 ENOG4108ESX Receptor DLK06_07865 ENOG41089BK Glutamine amido-transferase DLK06_07900 ENOG4105KUS lysozyme DLK06_07980 ENOG4105C5H ABC transporter DLK06_07985 ENOG41081QV Universal stress protein DLK06_08005 ENOG4105DKK Benzoate DLK06_08010 ENOG4105EW9 transcriptional regulator AsnC family DLK06_08015 ENOG4108NIW Leucine export protein LeuE DLK06_08020 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DLK06_08025 ENOG4105CC0 LysR family Transcriptional regulator DLK06_08035 ENOG4105CHU acetyl-coa acetyltransferase DLK06_08040 ENOG4105CHR reductase DLK06_08075 ENOG4107QMP dna polymerase iii subunits gamma and tau DLK06_08080 ENOG4105HSS phospholipase C DLK06_08090 ENOG4105C0A alcohol dehydrogenase DLK06_08145 ENOG4105CBC glutamate synthase DLK06_08450 ENOG4105UPP uncharacterized protein ydcA DLK06_08465 ENOG4105E4C Lytic transglycosylase catalytic DLK06_08515 ENOG4105DIJ Phosphoethanolamine transferase DLK06_08520 ENOG4105D8G Major Facilitator superfamily DLK06_08530 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DLK06_08535 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein DLK06_08560 ENOG4105DUU IucA IucC family protein DLK06_08570 ENOG4105DJU Siderophore biosynthesis protein DLK06_08575 ENOG4105CIF Ornithine Cyclodeaminase DLK06_08600 ENOG4107QZF nitrite reductase NADPH large subunit DLK06_08605 ENOG4108IFG nitrite reductase, (NAD(P)H) DLK06_08620 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) DLK06_08640 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DLK06_08645 ENOG4105CVM Molybdenum cofactor synthesis domain protein DLK06_08655 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DLK06_08660 ENOG4105T38 integral membrane protein DLK06_08685 ENOG4105CMR udp-glucose 4-epimerase DLK06_08735 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) DLK06_08795 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DLK06_08800 ENOG4105CUX Signal transduction histidine kinase DLK06_08825 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DLK06_08830 ENOG4105KNE Phosphatidate cytidylyltransferase DLK06_08840 ENOG4105DZP Membrane-associated zinc metalloprotease DLK06_08865 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DLK06_08880 ENOG4105Y3E Modulates RecA activity (By similarity) DLK06_08890 ENOG4105VEJ Heat shock protein DLK06_08895 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 DLK06_08910 ENOG4105F7P transcriptional regulator AsnC family DLK06_08920 ENOG4105C85 amino acid DLK06_08950 ENOG4105CHH sulfate transporter DLK06_08960 ENOG4105D8V Glucose sorbosone dehydrogenase DLK06_08970 ENOG4105BZU Histidine kinase DLK06_08985 ENOG4105DM4 PTS System DLK06_08990 ENOG4105DE4 1-phosphofructokinase DLK06_08995 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DLK06_09015 ENOG4108ZJF Glcg protein DLK06_09020 ENOG4105CWM branched-chain amino acid transport system II carrier protein DLK06_09025 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DLK06_09030 ENOG4105CC0 LysR family Transcriptional regulator DLK06_09040 ENOG4105M2J Glutaredoxin DLK06_09045 ENOG4105C8Y Acetylornithine aminotransferase DLK06_09050 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DLK06_09075 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DLK06_09105 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DLK06_09110 ENOG4105C4M (Ubiquinol oxidase) subunit I DLK06_09120 ENOG4105PV3 Inner membrane protein yqiJ DLK06_09140 ENOG4105HDD phospholipase DLK06_09145 ENOG4105CZN Potassium uptake protein DLK06_09155 ENOG4105C7B Threonine dehydratase DLK06_09185 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) DLK06_09190 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DLK06_09200 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) DLK06_09215 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DLK06_09255 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) DLK06_09260 ENOG4107VMU Membrane DLK06_09270 ENOG4105CNM Receptor DLK06_09275 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) DLK06_09285 ENOG4107QP7 CoA-transferase subunit A DLK06_09290 ENOG4107QNJ CoA-transferase subunit B DLK06_09295 ENOG4105CHU acetyl-coa acetyltransferase DLK06_09300 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase DLK06_09305 ENOG4105F2Z 3-oxoadipate enol-lactonase DLK06_09310 ENOG4105D2S major facilitator superfamily DLK06_09315 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase DLK06_09320 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta DLK06_09325 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha DLK06_09330 ENOG4105FF2 Type I DHQase DLK06_09335 ENOG4106JPM 3-dehydroshikimate dehydratase DLK06_09345 ENOG4105DZG Dehydrogenase DLK06_09355 ENOG4105MD1 YeeE YedE family protein DLK06_09370 ENOG4107HP6 Transcriptional regulator DLK06_09375 ENOG4108PTX LysR family Transcriptional regulator DLK06_09380 ENOG4105C1G acyl-Coa dehydrogenase DLK06_09405 ENOG4105DNH Major Facilitator DLK06_09415 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DLK06_09435 ENOG4105FUY alpha subunit DLK06_09445 ENOG4105CHR reductase DLK06_09465 ENOG4105F11 amine oxidase DLK06_09475 ENOG4105C26 Dehydrogenase DLK06_09480 ENOG4105F2Z 3-oxoadipate enol-lactonase DLK06_09485 ENOG4105CHU acetyl-coa acetyltransferase DLK06_09490 ENOG4107QNJ CoA-transferase subunit B DLK06_09495 ENOG4107QP7 CoA-transferase subunit A DLK06_09505 ENOG4105NN7 muconolactone delta-isomerase DLK06_09510 ENOG4105DTQ mandelate racemase muconate lactonizing DLK06_09515 ENOG4108KB2 LysR family Transcriptional regulator DLK06_09525 ENOG4107EJG GntR family transcriptional regulator DLK06_09545 ENOG4105CZJ Aldehyde dehydrogenase DLK06_09550 ENOG4105VT2 5-hydroxyisourate hydrolase DLK06_09555 ENOG4105C2W permease DLK06_09565 ENOG41061H0 Monooxygenase DLK06_09570 ENOG41073TP transcriptional regulator DLK06_09585 ENOG4107XKF NMT1 THI5 Like Domain Protein DLK06_09595 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DLK06_09615 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DLK06_09620 ENOG4105EMU Dehydrogenase DLK06_09655 ENOG4107Z3H Transcriptional regulator, TetR family DLK06_09660 ENOG4108PTX LysR family Transcriptional regulator DLK06_09670 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DLK06_09675 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr DLK06_09685 ENOG4105CSU acyl-Coa dehydrogenase DLK06_09695 ENOG4105CEY Amp-dependent synthetase and ligase DLK06_09725 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DLK06_09730 ENOG4108VBZ doxx family DLK06_09735 ENOG4108K3A Glutathione S-transferase DLK06_09745 ENOG4105DZG Dehydrogenase DLK06_09785 ENOG4106KR7 LysR family Transcriptional regulator DLK06_09810 ENOG4108JQ1 Dehydrogenase DLK06_09815 ENOG4105JSC dimethylmenaquinone methyltransferase DLK06_09835 ENOG4105D5K Hemolysin activator protein DLK06_09870 ENOG4105EVZ LysR family transcriptional regulator DLK06_09875 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DLK06_09880 ENOG4105C26 Dehydrogenase DLK06_09915 ENOG4105CZJ Aldehyde dehydrogenase DLK06_09920 ENOG4105C01 Dihydroxy-acid dehydratase DLK06_09930 ENOG4105DDW LysR family Transcriptional regulator DLK06_09935 ENOG4105EXW epimerase dehydratase DLK06_09945 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DLK06_09960 ENOG4105EHG Permease protein DLK06_09965 ENOG4105E0A ABC, transporter DLK06_09980 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DLK06_10015 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) DLK06_10060 ENOG4105ENX hydrolase DLK06_10065 ENOG4105EQ2 LysR family Transcriptional regulator DLK06_10070 ENOG4108BAS reductase DLK06_10085 ENOG4108R6W Transcriptional regulator, ARAC family DLK06_10105 ENOG4105X0I Fimbrial DLK06_10170 ENOG4105C08 Histidine kinase DLK06_10175 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DLK06_10180 ENOG4105C1P efflux transporter, rnd family, mfp subunit DLK06_10185 ENOG4105BZS acriflavin resistance protein DLK06_10200 ENOG4108IGT Dipeptidase DLK06_10205 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E DLK06_10215 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) DLK06_10220 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) DLK06_10230 ENOG4107T31 5'-nucleotidase DLK06_10240 ENOG4105WQI isochorismatase DLK06_10245 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase DLK06_10250 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) DLK06_10255 ENOG4105E0C molybdate abc transporter DLK06_10260 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DLK06_10265 ENOG4105F4R Transcriptional regulator mode DLK06_10270 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit DLK06_10275 ENOG4108YS2 small subunit DLK06_10280 ENOG4105F57 Anthranilate dioxygenase reductase DLK06_10305 ENOG4105CHR reductase DLK06_10320 ENOG4105D2S major facilitator superfamily DLK06_10325 ENOG4105CF7 AraC family transcriptional regulator DLK06_10330 ENOG4105DTD Dehydrogenase DLK06_10345 ENOG4108M0I Transcriptional regulator DLK06_10360 ENOG4105CRW Short chain fatty acid transporter DLK06_10365 ENOG4105CHU acetyl-coa acetyltransferase DLK06_10375 ENOG4107YNJ LysR family Transcriptional regulator DLK06_10390 ENOG4108IJ0 Aspartate ammonia-lyase DLK06_10400 ENOG4105CSH Transporter DLK06_10410 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DLK06_10415 ENOG4105KVH Transcriptional regulator DLK06_10420 ENOG4105UEI Transcriptional Regulator AraC Family DLK06_10435 ENOG4108VCT Sulfite exporter TauE/SafE DLK06_10440 ENOG4107S76 domain protein DLK06_10455 ENOG4105FFC UPF0187 protein DLK06_10465 ENOG4105CHR reductase DLK06_10480 ENOG4105CPP Dehydrogenase, E1 component DLK06_10485 ENOG4107R0V Pyruvate dehydrogenase DLK06_10490 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DLK06_10505 ENOG4105BZU Histidine kinase DLK06_10525 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) DLK06_10530 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DLK06_10575 ENOG4107U5X Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DLK06_10585 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) DLK06_10600 ENOG4105C28 cystathionine DLK06_10620 ENOG4105K59 histidine triad (HIT) protein DLK06_10645 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DLK06_10650 ENOG4105CNM Receptor DLK06_10675 ENOG4107TSN permease DLK06_10680 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) DLK06_10700 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) DLK06_10705 ENOG4108YZT Adenosylcobinamide kinase DLK06_10730 ENOG4108Z66 YbaK ebsC protein DLK06_10745 ENOG4105C1G acyl-Coa dehydrogenase DLK06_10750 ENOG4105C1G acyl-Coa dehydrogenase DLK06_10755 ENOG4105EEF Alkane 1-monooxygenase DLK06_10760 ENOG4105E7U AraC family transcriptional regulator DLK06_10765 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) DLK06_10770 ENOG4105K70 DNA-binding protein DLK06_10785 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family DLK06_10795 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins DLK06_10800 ENOG4108Z4V iron-sulfur cluster assembly DLK06_10815 ENOG4108ZIT Ferredoxin, 2FE-2S DLK06_10820 ENOG4105F8J Adenylate Guanylate cyclase DLK06_10830 ENOG4108JA2 transcriptioN-repair coupling factor DLK06_10850 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) DLK06_10855 ENOG4105K4T epimerase DLK06_10870 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase DLK06_10885 ENOG4108JQ6 ABC transporter DLK06_10900 ENOG4105DGW oligopeptidase A DLK06_10905 ENOG4107QSI ABC, transporter DLK06_10940 ENOG4105SG9 biopolymer transport protein, ExbD DLK06_10950 ENOG4107QP3 malate synthase g DLK06_10955 ENOG4105D6Z AFG1 family ATPase DLK06_10965 ENOG4107RN6 Monooxygenase DLK06_10970 ENOG4105DWU Membrane DLK06_10985 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DLK06_10990 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DLK06_11005 ENOG4108Z6B deaminase DLK06_11025 ENOG4108RTD type II secretion system protein K DLK06_11050 ENOG4105F8V Hydrolase, tatD family DLK06_11060 ENOG4107QRG dna polymerase iii DLK06_11070 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) DLK06_11075 ENOG4105BZ1 (ABC) transporter DLK06_11090 ENOG4105FA0 parb-like partition protein DLK06_11095 ENOG4107QJE Chromosome Partitioning Protein DLK06_11105 ENOG4108S0S Nucleotidyl transferase DLK06_11110 ENOG4105EHM Aminoglycoside phosphotransferase DLK06_11115 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) DLK06_11120 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) DLK06_11125 ENOG4105D2N Aldolase DLK06_11145 ENOG4108UHJ MAF-like protein DLK06_11150 ENOG4105EZE Cupin 4 family protein DLK06_11160 ENOG41080HT Transcriptional regulator, arsr family DLK06_11170 ENOG4105XPP Protein of unknown function (DUF1275) DLK06_11175 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme DLK06_11180 ENOG4105BZ1 (ABC) transporter DLK06_11190 ENOG4108ZX5 transcriptional regulator DLK06_11200 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DLK06_11205 ENOG4105CK7 Sodium proline symporter DLK06_11210 ENOG4105EW9 transcriptional regulator AsnC family DLK06_11215 ENOG4105C26 Dehydrogenase DLK06_11220 ENOG4105YGK Pfam:UPF0157 DLK06_11235 ENOG4108T58 Mg2 transport protein CorA DLK06_11245 ENOG4108YYC ycei family DLK06_11255 ENOG4105CV1 Transketolase (EC 2.2.1.1) DLK06_11280 ENOG4108HWY Beta-lactamase DLK06_11300 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DLK06_11305 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DLK06_11325 ENOG4105X0I Fimbrial DLK06_11360 ENOG4108R4R Iron-regulated virulence regulatory protein DLK06_11365 ENOG4108IPJ Membrane DLK06_11375 ENOG4105ETS cytosine purines uracil thiamine allantoin DLK06_11400 ENOG4105HEI LysR family (Transcriptional regulator DLK06_11415 ENOG41067SE Tetr family transcriptional regulator DLK06_11430 ENOG4105EW9 transcriptional regulator AsnC family DLK06_11440 ENOG4105CDA abc transporter atp-binding protein DLK06_11445 ENOG4105DRP amino acid AbC transporter DLK06_11450 ENOG4105EAD ABC transporter DLK06_11465 ENOG4107T8P acyl-Coa dehydrogenase DLK06_11480 ENOG4105D01 (LipO)protein DLK06_11485 ENOG4105D01 (LipO)protein DLK06_11490 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DLK06_11495 ENOG4108UMI ABC transporter, permease DLK06_11500 ENOG4105C3G gtp-binding protein DLK06_11525 ENOG4108UMN azlc family DLK06_11530 ENOG4105ZED uncharacterized protein ygaH DLK06_11560 ENOG4106AXJ AraC family transcriptional regulator DLK06_11565 ENOG4108V06 Glutathione peroxidase DLK06_11575 ENOG4105CHM Aminotransferase DLK06_11580 ENOG4105CK2 sodium dicarboxylate symporter DLK06_11590 ENOG4105C0B DNA polymerase III (alpha subunit) DLK06_11615 ENOG4108JU3 Alkyl hydroperoxide reductase DLK06_11630 ENOG4108KB2 LysR family Transcriptional regulator DLK06_11635 ENOG4105CAU Arsenical resistance protein, ArsH DLK06_11640 ENOG4105D6J arsenicaL-resistance protein DLK06_11650 ENOG41082YX Transcriptional regulator, arsr family DLK06_11665 ENOG4105CPN adenine deaminase DLK06_11675 ENOG4105CBN LysR family transcriptional regulator DLK06_11685 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease DLK06_11695 ENOG4105E2B Taurine dioxygenase DLK06_11700 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DLK06_11705 ENOG4108IY8 ABC, transporter DLK06_11710 ENOG4106FTQ Taurine ABC transporter, periplasmic DLK06_11720 ENOG4105C54 Major Facilitator superfamily DLK06_11745 ENOG4105C4M (Ubiquinol oxidase) subunit I DLK06_11750 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DLK06_11760 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DLK06_11765 ENOG4108K70 Transcriptional regulator DLK06_11780 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DLK06_11785 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase DLK06_11800 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) DLK06_11805 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase DLK06_11830 ENOG41067MG lrgb family DLK06_11835 ENOG4105VAW lrga family DLK06_11840 ENOG4105CMU LysR family (Transcriptional regulator DLK06_11845 ENOG4108SHQ Glutathione S-transferase DLK06_11850 ENOG4105CYM Glutathione S-transferase DLK06_11870 ENOG4105CBN LysR family transcriptional regulator DLK06_11875 ENOG4105CHR reductase DLK06_11885 ENOG4105D7W serine acetyltransferase DLK06_11890 ENOG4105ESN nucleotide-binding protein DLK06_11895 ENOG4105C9B Cysteine desulfurase DLK06_11905 ENOG4105EXG Transcriptional regulator DLK06_11910 ENOG4105CT1 (ABC) transporter DLK06_11915 ENOG4107RP9 extracellular solute-binding protein, family 3 DLK06_11925 ENOG4108HW4 amino acid AbC transporter DLK06_11945 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DLK06_11950 ENOG4105BZU Histidine kinase DLK06_11960 ENOG4105EW9 transcriptional regulator AsnC family DLK06_11990 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DLK06_12035 ENOG4105HEI LysR family (Transcriptional regulator DLK06_12050 ENOG4105D2S major facilitator superfamily DLK06_12065 ENOG4105CEY Amp-dependent synthetase and ligase DLK06_12070 ENOG4105R8C Transcriptional regulator DLK06_12075 ENOG4105C1G acyl-Coa dehydrogenase DLK06_12080 ENOG4107QX3 carboxylase DLK06_12085 ENOG4105E39 Enoyl-CoA hydratase DLK06_12100 ENOG4105CC0 LysR family Transcriptional regulator DLK06_12115 ENOG4105CSU acyl-Coa dehydrogenase DLK06_12125 ENOG4105EQ0 Major Facilitator superfamily DLK06_12135 ENOG4107QNJ CoA-transferase subunit B DLK06_12140 ENOG4107QP7 CoA-transferase subunit A DLK06_12145 ENOG4107RGD Major Facilitator superfamily DLK06_12150 ENOG4105C1G acyl-Coa dehydrogenase DLK06_12155 ENOG4105E39 Enoyl-CoA hydratase DLK06_12160 ENOG4105CHR reductase DLK06_12165 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DLK06_12170 ENOG4105CHU acetyl-coa acetyltransferase DLK06_12180 ENOG4105EQ0 Major Facilitator superfamily DLK06_12185 ENOG4105EA8 2-Nitropropane dioxygenase DLK06_12190 ENOG4108UKI Enoyl-CoA hydratase DLK06_12205 ENOG4105C1G acyl-Coa dehydrogenase DLK06_12210 ENOG4107RGD Major Facilitator superfamily DLK06_12215 ENOG4108KAZ Involved in phosphonate degradation (By similarity) DLK06_12220 ENOG4107STF Involved in phosphonate degradation (By similarity) DLK06_12230 ENOG4107RCV ABC transporter, permease DLK06_12235 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DLK06_12240 ENOG4105C4Y ABC transporter DLK06_12255 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase DLK06_12260 ENOG4107HP6 Transcriptional regulator DLK06_12270 ENOG4105HEI LysR family (Transcriptional regulator DLK06_12310 ENOG4107YAU phenylacetic acid degradation protein DLK06_12315 ENOG4108Z0R Transferase DLK06_12320 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein DLK06_12325 ENOG4105DZS Phenylacetate-CoA ligase DLK06_12330 ENOG4105CHU acetyl-coa acetyltransferase DLK06_12335 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DLK06_12340 ENOG4108UKI Enoyl-CoA hydratase DLK06_12345 ENOG4105E39 Enoyl-CoA hydratase DLK06_12350 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DLK06_12355 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit DLK06_12360 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit DLK06_12365 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit DLK06_12370 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit DLK06_12375 ENOG4105DXM phenylacetic acid degradation protein DLK06_12380 ENOG4105EJQ L-serine dehydratase DLK06_12400 ENOG4108Z4X TRANSCRIPTIONal DLK06_12410 ENOG4105WPN DNA integration recombination invertion protein DLK06_12435 ENOG4107Y2X deaminase DLK06_12445 ENOG4105EMY transcriptional regulator DLK06_12540 ENOG4108HW3 (ABC) transporter DLK06_12550 ENOG4105MRR Transcriptional regulator (By similarity) DLK06_12565 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF DLK06_12570 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DLK06_12585 ENOG4105E2A Dehydrogenase DLK06_12590 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) DLK06_12625 ENOG4105CKT filamentous hemagglutinin DLK06_12630 ENOG4105D5K Hemolysin activator protein DLK06_12635 ENOG4107R4J Chloride channel DLK06_12640 ENOG4108JIK carboxylase DLK06_12660 ENOG4105C5A transporter DLK06_12665 ENOG4108WAV Transcriptional regulator DLK06_12675 ENOG4108WQI RNA Polymerase DLK06_12685 ENOG4105E18 UPF0276 protein DLK06_12740 ENOG4105ECR NmrA family DLK06_12745 ENOG4105KVH Transcriptional regulator DLK06_12795 ENOG4105D2S major facilitator superfamily DLK06_12805 ENOG4105CPW cytochrome b561 DLK06_12810 ENOG4107VGR Catalase DLK06_12825 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) DLK06_12835 ENOG4105CD3 dihydroorotase DLK06_12855 ENOG4105D5Q Arginine ornithine antiporter DLK06_12860 ENOG4105CRN Aminoglycoside phosphotransferase DLK06_12870 ENOG4108ZX5 transcriptional regulator DLK06_12890 ENOG4108Z4U Ferredoxin DLK06_12900 ENOG4107ZBN O-methyltransferase DLK06_12920 ENOG4105C42 Type I secretion membrane fusion protein (HlyD DLK06_12930 ENOG4105DFG type I secretion outer membrane protein DLK06_12935 ENOG4108IUZ ABC transporter DLK06_12940 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA DLK06_12950 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase DLK06_12955 ENOG4105C2X Arabinose 5-phosphate isomerase DLK06_13090 ENOG4108TFU terminase (Small subunit) DLK06_13170 ENOG4108NF7 phage-type endonuclease DLK06_13180 ENOG4105C4R Atp-dependent dna helicase DLK06_13185 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) DLK06_13255 ENOG4107YPT transcriptional regulator DLK06_13270 ENOG4105CUY Mechanosensitive ion channel DLK06_13315 ENOG41064MX Tetr family transcriptional regulator DLK06_13335 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) DLK06_13355 ENOG4105F2W methyltransferase DLK06_13360 ENOG4105EW9 transcriptional regulator AsnC family DLK06_13370 ENOG4105II7 pyrroline-5-carboxylate reductase DLK06_13380 ENOG4105VEQ Cold shock protein DLK06_13385 ENOG4105D1S lipid A biosynthesis DLK06_13390 ENOG410829K Lysine exporter protein (Lyse ygga) DLK06_13425 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DLK06_13475 ENOG4108KB2 LysR family Transcriptional regulator DLK06_13485 ENOG4105FUY alpha subunit DLK06_13490 ENOG4108UKV benzoate 1,2-dioxygenase DLK06_13495 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein DLK06_13500 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase DLK06_13505 ENOG4105DKK Benzoate DLK06_13510 ENOG4105D2S major facilitator superfamily DLK06_13525 ENOG4105CQ7 ATP-dependent helicase DLK06_13530 ENOG4105D3R alkyl hydroperoxide reductase DLK06_13550 ENOG4108JU3 Alkyl hydroperoxide reductase DLK06_13560 ENOG4108K3A Glutathione S-transferase DLK06_13570 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) DLK06_13575 ENOG4108TGY Glutathione S-transferase DLK06_13585 ENOG4108ZG0 Ompa motb domain protein DLK06_13590 ENOG4105CD3 dihydroorotase DLK06_13620 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DLK06_13635 ENOG4108UKZ OsmC family DLK06_13645 ENOG4107RYR Transcriptional regulator, Crp Fnr family DLK06_13650 ENOG4105CPC Aldo Keto reductase DLK06_13665 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DLK06_13680 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DLK06_13690 ENOG4105DFP Integrase DLK06_13765 ENOG4105E4C Lytic transglycosylase catalytic DLK06_14025 ENOG4105CFH Aspartokinase DLK06_14035 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DLK06_14045 ENOG4105CPW cytochrome b561 DLK06_14050 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) DLK06_14055 ENOG4105C7N Xanthine uracil vitamin C permease DLK06_14085 ENOG4105F95 Monooxygenase DLK06_14090 ENOG4105JQZ Methyltransferase DLK06_14095 ENOG4105EJC lysr family transcriptional regulator DLK06_14105 ENOG4106DSS Tartrate dehydratase subunit alpha DLK06_14110 ENOG4107GFK fumarate DLK06_14120 ENOG4107RN6 Monooxygenase DLK06_14140 ENOG4105DDY UPF0142 protein ycaO DLK06_14145 ENOG4105EPF Outer membrane porin DLK06_14150 ENOG4105D2S major facilitator superfamily DLK06_14155 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) DLK06_14160 ENOG4105E6M Sulphatase-modifying factor protein DLK06_14175 ENOG4105E3J oxidoreductase DLK06_14190 ENOG4108SC4 )-transporter DLK06_14195 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase DLK06_14210 ENOG4105C1G acyl-Coa dehydrogenase DLK06_14215 ENOG4105EPF Outer membrane porin DLK06_14220 ENOG4105NI3 Protein of unknown function (DUF3237) DLK06_14235 ENOG4105JXH GntR family transcriptional regulator DLK06_14240 ENOG4105CZJ Aldehyde dehydrogenase DLK06_14250 ENOG4105EQX glucarate dehydratase DLK06_14255 ENOG4105DJB Major Facilitator Superfamily DLK06_14260 ENOG4105CTX dehydratase DLK06_14265 ENOG4105DJP Membrane DLK06_14270 ENOG4108ZX5 transcriptional regulator DLK06_14275 ENOG4107RGH Aldehyde dehydrogenase DLK06_14295 ENOG4105C85 amino acid DLK06_14315 ENOG4105C26 Dehydrogenase DLK06_14335 ENOG4105CUB amino acid DLK06_14345 ENOG4105C85 amino acid DLK06_14355 ENOG4107Y60 (LipO)protein DLK06_14365 ENOG4106B0W Curli production assembly transport component CsgG DLK06_14380 ENOG4108M3P Membrane DLK06_14395 ENOG4105DFP Integrase DLK06_14450 ENOG4105F9F transposase DLK06_14505 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DLK06_14525 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) DLK06_14545 ENOG4108JQ5 ABC transporter DLK06_14550 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component DLK06_14555 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component DLK06_14560 ENOG4105E43 Extracellular solute-binding protein, family 5 DLK06_14565 ENOG4105E9H Lytic Murein transglycosylase DLK06_14565 ENOG4105E9H Lytic Murein transglycosylase DLK06_14570 ENOG4108JDX DNA polymerase iii, epsilon subunit DLK06_14580 ENOG4105E09 nadh pyrophosphatase DLK06_14590 ENOG4105W4M Transport-associated protein DLK06_14600 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DLK06_14615 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DLK06_14635 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family DLK06_14640 ENOG4105D0A hydroxylase DLK06_14645 ENOG4107RAQ aminopeptidase DLK06_14685 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DLK06_14700 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DLK06_14710 ENOG4105D82 Glutamate dehydrogenase DLK06_14715 ENOG4108R3D Electron transport complex DLK06_14720 ENOG4105CSM endonuclease III DLK06_14745 ENOG4105CJN penicillin-binding protein DLK06_14750 ENOG4106H78 methyltransferase DLK06_14765 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) DLK06_14775 ENOG4105CQM Urea amidohydrolase subunit alpha DLK06_14800 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion DLK06_14805 ENOG4107RET Isocitrate lyase DLK06_14815 ENOG4105C37 (CBS) domain DLK06_14820 ENOG4105D4T Citrate transporter DLK06_14840 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) DLK06_14855 ENOG4108MRJ DLK06_14875 ENOG4105VCQ rubredoxin DLK06_14880 ENOG4107QZF nitrite reductase NADPH large subunit DLK06_14885 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) DLK06_14890 ENOG4105C5Q Transcriptional regulator DLK06_14915 ENOG4107U91 Rhomboid family DLK06_14920 ENOG4105CV6 ABC transporter, permease DLK06_14925 ENOG4108I0Y (ABC) transporter DLK06_14930 ENOG4108UJV acyl-CoA thioesterase i DLK06_14950 ENOG4107RNH Outer membrane receptor FepA DLK06_14965 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) DLK06_14970 ENOG4105E6M Sulphatase-modifying factor protein DLK06_14990 ENOG4105CJ3 phosphate transporter DLK06_14995 ENOG4105C3R Methionine synthase DLK06_15015 ENOG4105CSP Major Facilitator Superfamily DLK06_15025 ENOG4108PZW LysR family Transcriptional regulator DLK06_15040 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) DLK06_15045 ENOG4105EU0 Major facilitator Superfamily DLK06_15050 ENOG4108R6W Transcriptional regulator, ARAC family DLK06_15055 ENOG4105CSV Glutaminase DLK06_15060 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DLK06_15065 ENOG4105CSH Transporter DLK06_15075 ENOG4105C7K acetolactate synthase DLK06_15090 ENOG4105CHR reductase DLK06_15095 ENOG4108MXF Alpha Beta Hydrolase DLK06_15105 ENOG4105DJB Major Facilitator Superfamily DLK06_15120 ENOG4105CHR reductase DLK06_15140 ENOG41069M3 Transcriptional regulator DLK06_15165 ENOG4105CND Glycosyl transferase, family 2 DLK06_15170 ENOG4107BJW polysaccharide deacetylase DLK06_15180 ENOG4108VWS Yaeq family DLK06_15190 ENOG4105CKI cobalamin synthesis protein DLK06_15215 ENOG4105C94 Transporter DLK06_15220 ENOG4105C94 Transporter DLK06_15225 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) DLK06_15255 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DLK06_15260 ENOG4105C0R drug resistance transporter emrb qaca subfamily DLK06_15265 ENOG4105CW7 secretion protein, HlyD family DLK06_15270 ENOG4108VUY thioesterase Superfamily protein DLK06_15275 ENOG4105D52 delta-aminolevulinic acid dehydratase DLK06_15280 ENOG4105MWK D-amino acid dehydrogenase, small subunit DLK06_15285 ENOG4105ECP epimerase DLK06_15305 ENOG4107RH8 nuclease SbcCD subunit D DLK06_15310 ENOG4105EYH Exonuclease DLK06_15315 ENOG4105DFA alanine racemase domain protein DLK06_15320 ENOG4105CZX twitching motility protein DLK06_15325 ENOG4105CZX twitching motility protein DLK06_15330 ENOG41090R7 Ferric uptake DLK06_15340 ENOG4105VDB UPF0125 protein DLK06_15360 ENOG4105E7A Glutamine amidotransferase DLK06_15375 ENOG4107QKV phosphomannomutase DLK06_15385 ENOG4105C4R Atp-dependent dna helicase DLK06_15390 ENOG4108ZG0 Ompa motb domain protein DLK06_15395 ENOG4106HNH Acyl-transferase DLK06_15410 ENOG4107QMS site-determining protein DLK06_15425 ENOG4105CCF Lysine exporter protein (Lyse ygga) DLK06_15430 ENOG4105CNU cell division protein FtsK DLK06_15435 ENOG4105C3M thioredoxin reductase DLK06_15440 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) DLK06_15450 ENOG4105KEG ribosomal-protein-alanine acetyltransferase DLK06_15475 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DLK06_15480 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) DLK06_15490 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) DLK06_15505 ENOG4108YXA Membrane DLK06_15515 ENOG4105C4K Nad synthetase DLK06_15530 ENOG4105E3J oxidoreductase DLK06_15535 ENOG4105C26 Dehydrogenase DLK06_15540 ENOG4105DVW rieske (2Fe-2S) DLK06_15550 ENOG4105C94 Transporter DLK06_15555 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DLK06_15560 ENOG4105EJC lysr family transcriptional regulator DLK06_15580 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DLK06_15590 ENOG4105DFP Integrase DLK06_15945 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DLK06_15950 ENOG4105C34 Pseudouridine synthase DLK06_15955 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DLK06_15960 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DLK06_15975 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) DLK06_16005 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DLK06_16035 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DLK06_16045 ENOG4105DWF phosphomethylpyrimidine kinase DLK06_16050 ENOG4109066 lysm domain bon superfamily protein DLK06_16060 ENOG4105CHR reductase DLK06_16065 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DLK06_16075 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein DLK06_16080 ENOG4108BPE -transporting atpase DLK06_16085 ENOG4107RTD sua5 ycio yrdc ywlc family protein DLK06_16090 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) DLK06_16095 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) DLK06_16100 ENOG4105FE9 pseudouridine synthase DLK06_16110 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DLK06_16115 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DLK06_16125 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DLK06_16135 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase DLK06_16140 ENOG4106UW1 Major Facilitator superfamily DLK06_16220 ENOG4108ZXE DLK06_16245 ENOG4105ECI YeeC-like protein DLK06_16255 ENOG4105F6A helicase DLK06_16260 ENOG4105D85 methylase DLK06_16265 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) DLK06_16280 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DLK06_16290 ENOG4105HF0 Membrane DLK06_16305 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY DLK06_16315 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) DLK06_16380 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DLK06_16385 ENOG4105D1F ATP-binding protein DLK06_16395 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) DLK06_16430 ENOG4105K6H D-cysteine desulfhydrase DLK06_16435 ENOG4105CBX hi0933 family DLK06_16460 ENOG4105DP0 ferredoxin-NADP reductase DLK06_16465 ENOG4105DUM transcriptional regulator, lysR family DLK06_16485 ENOG4105C8S subunit m DLK06_16490 ENOG4105D65 subunit l DLK06_16500 ENOG4107UFS subunit j DLK06_16515 ENOG4108IEH NADH dehydrogenase subunit g DLK06_16520 ENOG4107QIZ NADH dehydrogenase DLK06_16525 ENOG4105GKE subunit e DLK06_16545 ENOG4105BZU Histidine kinase DLK06_16555 ENOG4105E0F Histidine kinase DLK06_16560 ENOG4107EXC regulatoR DLK06_16565 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DLK06_16575 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DLK06_16580 ENOG4105JAB phenazine biosynthesis protein, phzf family DLK06_16590 ENOG4107RRE RNA-directed DNA polymerase DLK06_16640 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) DLK06_16645 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) DLK06_16655 ENOG4105ETT transcriptional Regulator, LysR family DLK06_16675 ENOG4105CH2 amidohydrolase DLK06_16705 ENOG4106P55 Transcriptional regulator DLK06_16725 ENOG4106P55 Transcriptional regulator DLK06_16730 ENOG4107EFR Flavocytochrome c DLK06_16755 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DLK06_16760 ENOG4107RGD Major Facilitator superfamily DLK06_16765 ENOG4105C1G acyl-Coa dehydrogenase DLK06_16770 ENOG4105ETT transcriptional Regulator, LysR family DLK06_16780 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) DLK06_16790 ENOG4107R08 Integrase DLK06_16795 ENOG4105UMD exodeoxyribonuclease X DLK06_16820 ENOG4108JJB ABC transporter DLK06_16860 ENOG4105F9F transposase DLK06_16975 ENOG4108E1C hydrolase DLK06_17020 ENOG4105ED4 portal protein DLK06_17060 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) DLK06_17065 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) DLK06_17070 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DLK06_17090 ENOG4105E3B Multicopper oxidase DLK06_17100 ENOG4108HCJ Hydrolase DLK06_17105 ENOG4105DJV ribulose-phosphate 3-epimerase DLK06_17115 ENOG4105C4W S-formylglutathione hydrolase DLK06_17130 ENOG41072GX Peptidase M22 Glycoprotease DLK06_17135 ENOG4108Z0R Transferase DLK06_17190 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DLK06_17195 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) DLK06_17200 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DLK06_17270 ENOG4105K56 Transcriptional regulator DLK06_17275 ENOG4108ZHJ Organic hydroperoxide resistance protein DLK06_17280 ENOG4107QHF type ii secretion system protein e DLK06_17300 ENOG4105C2M dna polymerase I DLK06_17305 ENOG4108VIA integral membrane protein DLK06_17310 ENOG4105II7 pyrroline-5-carboxylate reductase DLK06_17315 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DLK06_17325 ENOG4105C9X ppx gppa phosphatase DLK06_17335 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DLK06_17355 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DLK06_17380 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DLK06_17385 ENOG41082NX 50s ribosomal protein l35 DLK06_17400 ENOG4105W39 Membrane DLK06_17405 ENOG4105CYM Glutathione S-transferase DLK06_17425 ENOG4105CEY Amp-dependent synthetase and ligase DLK06_17430 ENOG4105N42 UPF0307 protein DLK06_17435 ENOG41080Z8 PHOSPHOCARRIER protein DLK06_17455 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DLK06_17460 ENOG4105DJ0 Poly(A) Polymerase DLK06_17465 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein DLK06_17470 ENOG4105DXN mazG family DLK06_17480 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DLK06_17495 ENOG4105C6T cysteine synthase DLK06_17500 ENOG4105BZU Histidine kinase DLK06_17505 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase DLK06_17510 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DLK06_17515 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) DLK06_17530 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) DLK06_17535 ENOG4105W8H transhydrogenase (subunit alpha DLK06_17540 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) DLK06_17545 ENOG4106UX7 integral membrane protein DLK06_17560 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DLK06_17570 ENOG4107RSM transcriptional regulator DLK06_17580 ENOG4105CUZ uba thif-type nad fad binding protein DLK06_17590 ENOG4107QM5 aconitate hydratase DLK06_17595 ENOG4105F8V Hydrolase, tatD family DLK06_17610 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) DLK06_17655 ENOG4107R3N Filamentation induced by cAMP protein fic DLK06_17680 ENOG4105C2W permease DLK06_17685 ENOG4105DRB nucleoside-specific channel-forming protein DLK06_17700 ENOG4105EMY transcriptional regulator DLK06_17820 ENOG4105UYK outer membrane protein a DLK06_17885 ENOG4105BZU Histidine kinase DLK06_17890 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DLK06_17895 ENOG4108ZP8 Acetolactate synthase small subunit DLK06_17900 ENOG4105C7K acetolactate synthase DLK06_17920 ENOG4105DJY efflux transporter, rnd family, mfp subunit DLK06_17925 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) DLK06_17930 ENOG4105ENJ RND efflux system, outer membrane lipoprotein DLK06_17935 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH DLK06_17945 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) DLK06_17950 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DLK06_17960 ENOG4105VW4 glutaredoxin 3 DLK06_17980 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) DLK06_18000 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) DLK06_18020 ENOG4105WVQ Fe-S assembly protein IscX DLK06_18035 ENOG4105CN1 protease DLK06_18050 ENOG4106HB6 Alpha beta hydrolase DLK06_18060 ENOG4105C26 Dehydrogenase DLK06_18065 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family DLK06_18070 ENOG4105C6Z Gluconate DLK06_18075 ENOG4108UHU Aldolase DLK06_18080 ENOG4105C01 Dihydroxy-acid dehydratase DLK06_18090 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) DLK06_18095 ENOG4108DNC Involved in acetate metabolism (By similarity) DLK06_18100 ENOG4107GFK fumarate DLK06_18120 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DLK06_18130 ENOG4108ESX Receptor DLK06_18140 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DLK06_18150 ENOG4105DWV Homoserine O-trans-acetylase DLK06_18250 ENOG4105CIY formyltetrahydrofolate deformylase DLK06_18260 ENOG4107RGH Aldehyde dehydrogenase DLK06_18265 ENOG4105KDC 50s ribosomal protein l28 DLK06_18270 ENOG4105W0E 50S ribosomal protein L33 DLK06_18275 ENOG4105CKD glutathione-regulated potassium-efflux system protein DLK06_18295 ENOG4105VFU Rna-binding protein DLK06_18300 ENOG4105C4R Atp-dependent dna helicase DLK06_18315 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DLK06_18325 ENOG4105KVH Transcriptional regulator DLK06_18330 ENOG4105CIS alcohol dehydrogenase DLK06_18335 ENOG41069P5 Protein slyX homolog DLK06_18340 ENOG4105C5H ABC transporter DLK06_18350 ENOG4105D1S lipid A biosynthesis DLK06_18360 ENOG4105CK2 sodium dicarboxylate symporter DLK06_18415 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DLK06_18465 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase DLK06_18480 ENOG4108W5M transcriptional regulator DLK06_18495 ENOG4105D29 Helix-turn-helix type 11 domain protein DLK06_18500 ENOG4107XGZ Hydrolase DLK06_18505 ENOG4105EI2 Pseudouridine synthase DLK06_18515 ENOG4105C03 ribonuclease DLK06_18535 ENOG4105CBN LysR family transcriptional regulator DLK06_18545 ENOG4105CSA Coproporphyrinogen iii oxidase DLK06_18555 ENOG4107QI1 Mate efflux family protein DLK06_18565 ENOG4107T8P acyl-Coa dehydrogenase DLK06_18595 ENOG4105BZ8 glutamate synthase DLK06_18605 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) DLK06_18610 ENOG4105C5X domain protein DLK06_18625 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DLK06_18635 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase DLK06_18645 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) DLK06_18650 ENOG4108JU5 Magnesium and cobalt efflux protein DLK06_18655 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) DLK06_18690 ENOG4108VAU general secretion pathway protein G DLK06_18695 ENOG4105D7Q type ii secretion system DLK06_18700 ENOG4105C25 Primosomal protein n' DLK06_18710 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) DLK06_18720 ENOG4105DVC DnaJ domain protein DLK06_18725 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) DLK06_18730 ENOG4107QUT magnesium and cobalt transport protein CorA DLK06_18735 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) DLK06_18750 ENOG4107QYX exodeoxyribonuclease v alpha DLK06_18755 ENOG4107QKA exodeoxyribonuclease V beta DLK06_18760 ENOG4105DSY exodeoxyribonuclease V, gamma DLK06_18770 ENOG4105CSR polyphosphate kinase 2 DLK06_18780 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DLK06_18795 ENOG41061H0 Monooxygenase DLK06_18800 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase DLK06_18805 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase DLK06_18820 ENOG4105D65 subunit l DLK06_18825 ENOG4108ZE9 Monovalent cation H antiporter subunit C DLK06_18830 ENOG4107R4Z monovalent cation h antiporter subunit d DLK06_18835 ENOG4105SC1 monovalent cation H antiporter subunit E DLK06_18840 ENOG4105W4C monovalent cation H antiporter subunit F DLK06_18845 ENOG4105KJM monovalent cation h antiporter subunit g DLK06_18850 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) DLK06_18860 ENOG4105CHV Transcription elongation factor NusA DLK06_18885 ENOG4107EJC Preprotein translocase subunit SecG DLK06_18895 ENOG4107QHF type ii secretion system protein e DLK06_18910 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DLK06_18920 ENOG4105C2N RNA methyltransferase TrmH family group 3 DLK06_18935 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DLK06_18945 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) DLK06_18980 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DLK06_18985 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DLK06_19055 ENOG4108Z6Z Transcriptional regulator DLK06_19065 ENOG4107ZXU DSBA oxidoreductase DLK06_19080 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) DLK06_19100 ENOG4105D3Y Na H antiporter DLK06_19155 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DLK06_19160 ENOG4105PM1 preprotein translocase subunit SecE DLK06_19170 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DLK06_19200 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DLK06_19205 ENOG4105TV9 FHA Domain-Containing protein DLK06_19210 ENOG4105GVR general secretion pathway protein D DLK06_19225 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS DLK06_19250 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DLK06_19255 ENOG4108NEV two component transcriptional regulator, LytTR family DLK06_19260 ENOG4108HRK Histidine kinase DLK06_19275 ENOG4108UTW Plays a role in the regulation of phosphate uptake DLK06_19280 ENOG4105DFG type I secretion outer membrane protein DLK06_19290 ENOG4108RNG Permease of the drug metabolite transporter DLK06_19310 ENOG41087AY ADP-Ribose pyrophosphatase DLK06_19315 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) DLK06_19320 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters DLK06_19325 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) DLK06_19330 ENOG4105CNI cell division protein FtsW DLK06_19345 ENOG4105CE1 Ferrous iron transport protein b DLK06_19355 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DLK06_19360 ENOG4105T95 Thiol disulfide interChange protein DLK06_19365 ENOG4105D6E homoserine dehydrogenase DLK06_19375 ENOG41061WM D-Alanyl-D-Alanine DLK06_19385 ENOG4107TUY Histidine kinase DLK06_19390 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DLK06_19395 ENOG4105CN1 protease DLK06_19400 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DLK06_19405 ENOG4108K5H permease YjgP YjgQ family protein DLK06_19445 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DLK06_19455 ENOG4105BZU Histidine kinase DLK06_19470 ENOG4105C0P Mg chelatase subunit ChlI DLK06_19475 ENOG4108YYH Nadph-dependent fmn reductase DLK06_19480 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DLK06_19485 ENOG4105FB2 class II Aldolase DLK06_19490 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DLK06_19505 ENOG41090KI Outer membrane porin DLK06_19510 ENOG4105F0N pyrophosphate phospho-hydrolase DLK06_19525 ENOG4105CEY Amp-dependent synthetase and ligase DLK06_19530 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DLK06_19535 ENOG41079KZ Major Facilitator Superfamily DLK06_19540 ENOG4105EN6 Membrane DLK06_19550 ENOG4105EE5 Membrane protein terC DLK06_19555 ENOG4108URH decarboxylase DLK06_19560 ENOG4105C0R drug resistance transporter emrb qaca subfamily DLK06_19570 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DLK06_19590 ENOG4105CCT upf0313 protein DLK06_19610 ENOG4105CS1 NAD(P)H quinone oxidoreductase DLK06_19625 ENOG4105C6T cysteine synthase DLK06_19655 ENOG4105Y7M Transcriptional regulator, TetR family DLK06_19690 ENOG4105C79 DNA protecting protein DprA DLK06_19705 ENOG4108IND Tetr family transcriptional regulator DLK06_19710 ENOG4107RTG Major Facilitator superfamily DLK06_19720 ENOG4108V06 Glutathione peroxidase DLK06_19735 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) DLK06_19745 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) DLK06_19760 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DLK06_19785 ENOG4105FDK ABC transporter DLK06_19790 ENOG4105FAV ABC, transporter DLK06_19800 ENOG4105EZR dyp-type peroxidase family protein DLK06_19805 ENOG4107R1I NAD-dependent malic enzyme DLK06_19835 ENOG4105EUB pirin domain protein DLK06_19850 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DLK06_19855 ENOG4106MP8 UPF0754 membrane protein DLK06_19860 ENOG4108VBZ doxx family DLK06_19865 ENOG4105DQR SNARE associated Golgi DLK06_19880 ENOG4107QJE Chromosome Partitioning Protein DLK06_19890 ENOG4107PSF BolA-like protein DLK06_19935 ENOG4105C1G acyl-Coa dehydrogenase DLK06_19940 ENOG4107RCI amp-dependent synthetase and ligase DLK06_19965 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DLK06_19975 ENOG4105CJP fad dependent oxidoreductase DLK06_19980 ENOG4105C85 amino acid DLK06_19985 ENOG4108594 Permease of the drug metabolite transporter DLK06_19990 ENOG4105CSH Transporter DLK06_19995 ENOG4105E39 Enoyl-CoA hydratase DLK06_20000 ENOG4105E39 Enoyl-CoA hydratase DLK06_20005 ENOG4105C1G acyl-Coa dehydrogenase DLK06_20015 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DLK06_20020 ENOG4105C26 Dehydrogenase DLK06_20035 ENOG4105C85 amino acid DLK06_20040 ENOG4105M4H endoribonuclease L-psp DLK06_20055 ENOG4105EW9 transcriptional regulator AsnC family DLK06_20080 ENOG4105D3G Pseudouridine synthase DLK06_20155 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DLK06_20180 ENOG4108I0Z Aconitate hydratase DLK06_20185 ENOG4105BZN citrate synthase DLK06_20190 ENOG4105CR4 methylisocitrate lyase DLK06_20195 ENOG4105DRR Transcriptional regulator, GntR family DLK06_20205 ENOG4105CGF Aromatic amino acid aminotransferase DLK06_20210 ENOG4105CXG d-lactate dehydrogenase DLK06_20220 ENOG41073TP transcriptional regulator DLK06_20225 ENOG4105DAA L-lactate DLK06_20230 ENOG4107QKV phosphomannomutase DLK06_20240 ENOG4105C6Y Udp-glucose 6-dehydrogenase DLK06_20245 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DLK06_20250 ENOG4105D3Q Sugar transferase DLK06_20260 ENOG4105H63 Glycosyl transferase, family 2 DLK06_20270 ENOG4108TJN glycosyl transferase group 1 DLK06_20275 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase DLK06_20280 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DLK06_20285 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase DLK06_20290 ENOG4105C1B dTDP-glucose 4-6-dehydratase DLK06_20295 ENOG4105C6Y Udp-glucose 6-dehydrogenase DLK06_20315 ENOG4107QQG Dehydrogenase DLK06_20320 ENOG4105DAY polysaccharide export protein DLK06_20330 ENOG4105D75 Capsular exopolysaccharide family DLK06_20335 ENOG4108V1T peptidylprolyl cis-trans isomerase DLK06_20340 ENOG4108V1T peptidylprolyl cis-trans isomerase DLK06_20345 ENOG4105CJR Integral membrane protein (MviN DLK06_20350 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase DLK06_20355 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DLK06_20365 ENOG4105HSS phospholipase C DLK06_20390 ENOG4105EJ2 Transcriptional regulator DLK06_20395 ENOG41062JF Transcriptional regulator DLK06_20410 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DLK06_20415 ENOG4105UBK short-chain dehydrogenase reductase DLK06_20445 ENOG4107QZM n-acetylglutamate synthase DLK06_20450 ENOG4105GVF (ABC) transporter DLK06_20455 ENOG4105GVF (ABC) transporter DLK06_20460 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DLK06_20470 ENOG4108VM9 ABC, transporter DLK06_20475 ENOG4108R86 Transcriptional regulator DLK06_20480 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DLK06_20490 ENOG4105DTN riboflavin biosynthesis protein ribF DLK06_20495 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) DLK06_20505 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase DLK06_20545 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) DLK06_20600 ENOG4105CVE Lytic murein transglycosylase DLK06_20605 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DLK06_20610 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DLK06_20620 ENOG4105DFU Cell wall formation (By similarity) DLK06_20630 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DLK06_20635 ENOG4105DU1 integral membrane protein, terc DLK06_20645 ENOG4106032 Glutathionylspermidine synthase DLK06_20655 ENOG4107QUY Guanine deaminase DLK06_20660 ENOG4108UGV hypoxanthine phosphoribosyltransferase DLK06_20670 ENOG4105T95 Thiol disulfide interChange protein DLK06_20675 ENOG4105PGM cation diffusion facilitator family transporter DLK06_20690 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DLK06_20705 ENOG4105VG0 50S ribosomal protein l34 DLK06_20715 ENOG4105MRD Phage derived protein Gp49-like (DUF891) DLK06_20925 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) DLK06_20950 ENOG4105EUV Phenol 2-monooxygenase DLK06_21005 ENOG4108IJF Heavy metal efflux pump, CzcA DLK06_21045 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium DLK06_21055 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein DLK06_21060 ENOG4108WUH Transcriptional regulator, TetR family DLK06_21080 ENOG4108I6A alcohol dehydrogenase DLK06_21095 ENOG4105C4W S-formylglutathione hydrolase DLK06_21115 ENOG4105ECQ AraC Family Transcriptional Regulator DLK06_21125 ENOG4105CSH Transporter DLK06_21130 ENOG4105RPH Inner membrane protein YddG DLK06_21145 ENOG4108JA1 polyketide synthase DLK06_21150 ENOG4107QPD alcohol dehydrogenase DLK06_21160 ENOG4105D5G Transposase DLK06_21185 ENOG4105VUH addiction module killer protein DLK06_21190 ENOG4105YES addiction module antidote protein DLK06_21200 ENOG4105XUP Phage derived protein Gp49-like (DUF891)