locus-tag	class	description
MWH18_00010	COG0592	DNA-directed DNA polymerase activity
MWH18_00020	COG0187	DNA topoisomerase II activity
MWH18_00035	COG0488	(ABC) transporter
MWH18_00060	COG0596	Alpha beta hydrolase
MWH18_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MWH18_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MWH18_00105	COG0625	glutathione transferase activity
MWH18_00115	COG0733	neurotransmitter:sodium symporter activity
MWH18_00155	COG2233	PERMEase
MWH18_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_00205	COG2814	Major facilitator Superfamily
MWH18_00210	COG0656	L-ascorbic acid biosynthetic process
MWH18_00215	COG0583	DNA-binding transcription factor activity
MWH18_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MWH18_00235	COG1064	alcohol dehydrogenase
MWH18_00240	COG2818	Glycosylase
MWH18_00255	COG2826	transposase and inactivated derivatives, IS30 family
MWH18_00265	COG1194	a g-specific adenine glycosylase
MWH18_00280	COG5487	UPF0391 membrane protein
MWH18_00285	COG2983	Belongs to the UPF0260 family
MWH18_00290	COG2133	pyrroloquinoline quinone binding
MWH18_00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MWH18_00300	COG2116	formate transmembrane transporter activity
MWH18_00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MWH18_00330	COG0385	Bile acid
MWH18_00350	COG1683	Conserved Protein
MWH18_00365	COG0346	lactoylglutathione lyase activity
MWH18_00370	COG0625	glutathione transferase activity
MWH18_00380	COG1113	amino acid transport
MWH18_00390	COG0523	cobalamin synthesis protein
MWH18_00400	COG2188	Transcriptional regulator
MWH18_00430	COG0010	Belongs to the arginase family
MWH18_00440	COG0546	phosphoglycolate phosphatase activity
MWH18_00445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MWH18_00450	COG2826	transposase and inactivated derivatives, IS30 family
MWH18_00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MWH18_00480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MWH18_00485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MWH18_00580	COG0534	Mate efflux family protein
MWH18_00585	COG0436	Aminotransferase
MWH18_00590	COG2733	membrane
MWH18_00605	COG2918	glutathione biosynthetic process
MWH18_00620	COG3179	chitinase
MWH18_00635	COG3150	esterase
MWH18_00645	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MWH18_00655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MWH18_00665	COG2233	PERMEase
MWH18_00670	COG2351	hydroxyisourate hydrolase activity
MWH18_00705	COG3706	GGDEF domain
MWH18_00720	COG1393	Belongs to the ArsC family
MWH18_00725	COG0708	Exodeoxyribonuclease III
MWH18_00750	COG0189	ligase activity
MWH18_00770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MWH18_00780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MWH18_00795	COG4942	peptidase
MWH18_00805	COG0508	dehydrogenase complex catalyzes the overall conversion of
MWH18_00815	COG2119	membrane
MWH18_00820	COG4774	siderophore transport
MWH18_00825	COG0426	domain, Protein
MWH18_00825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MWH18_00850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MWH18_00870	COG1902	pentaerythritol trinitrate reductase activity
MWH18_00875	COG1519	Transferase
MWH18_00880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MWH18_00885	COG0668	transmembrane transport
MWH18_00895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MWH18_00900	COG1335	isochorismatase
MWH18_00905	COG1522	sequence-specific DNA binding
MWH18_00930	COG0784	Response regulator, receiver
MWH18_00930	COG2205	protein histidine kinase activity
MWH18_00930	COG2198	Histidine kinase
MWH18_00935	COG3162	membrane
MWH18_00940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MWH18_00950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MWH18_00970	COG1309	transcriptional regulator
MWH18_00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MWH18_00990	COG0352	thiamine-phosphate diphosphorylase activity
MWH18_00990	COG0351	phosphomethylpyrimidine kinase
MWH18_01000	COG2814	Major facilitator Superfamily
MWH18_01015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MWH18_01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MWH18_01040	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_01050	COG1335	isochorismatase
MWH18_01145	COG1309	transcriptional regulator
MWH18_01165	COG2814	Major facilitator Superfamily
MWH18_01170	COG0583	DNA-binding transcription factor activity
MWH18_01190	COG0667	Aldo Keto reductase
MWH18_01245	COG2249	NAD(P)H dehydrogenase (quinone) activity
MWH18_01260	COG4372	Transposase
MWH18_01275	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_01280	COG1881	PFAM PEBP family protein
MWH18_01285	COG2977	Belongs to the P-Pant transferase superfamily
MWH18_01290	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
MWH18_01295	COG2207	Transcriptional regulator
MWH18_01355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MWH18_01370	COG2329	Antibiotic biosynthesis monooxygenase
MWH18_01385	COG1132	(ABC) transporter
MWH18_01395	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MWH18_01405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MWH18_01435	COG0427	acetyl-CoA hydrolase
MWH18_01460	COG0659	secondary active sulfate transmembrane transporter activity
MWH18_01465	COG4221	oxidoreductase activity
MWH18_01470	COG2873	o-acetylhomoserine
MWH18_01475	COG0488	(ABC) transporter
MWH18_01560	COG0833	amino acid
MWH18_01605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MWH18_01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MWH18_01625	COG2226	methyltransferase
MWH18_01675	COG0070	glutamate synthase
MWH18_01675	COG0069	glutamate synthase activity
MWH18_01675	COG0067	glutamate synthase
MWH18_01680	COG0493	'glutamate synthase
MWH18_01690	COG1704	LemA family
MWH18_01695	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MWH18_01715	COG3307	-O-antigen
MWH18_01740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MWH18_01755	COG0194	GDP metabolic process
MWH18_01805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MWH18_01815	COG0335	large ribosomal subunit rRNA binding
MWH18_01825	COG5380	lipid catabolic process
MWH18_01830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MWH18_01845	COG5006	permease, DMT superfamily
MWH18_01850	COG5006	permease, DMT superfamily
MWH18_01855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MWH18_01860	COG0277	FAD linked oxidase domain protein
MWH18_01870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MWH18_01875	COG2249	NAD(P)H dehydrogenase (quinone) activity
MWH18_01890	COG1289	transmembrane transporter activity
MWH18_01900	COG0628	permease
MWH18_01905	COG1192	Involved in chromosome partitioning
MWH18_01935	COG0833	amino acid
MWH18_01940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MWH18_01945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MWH18_01955	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_01995	COG0583	DNA-binding transcription factor activity
MWH18_02025	COG0752	glycyl-tRNA synthetase alpha subunit
MWH18_02050	COG4109	DRTGG domain
MWH18_02055	COG1983	PspC domain protein
MWH18_02065	COG1960	acyl-CoA dehydrogenase activity
MWH18_02080	COG0408	coproporphyrinogen oxidase activity
MWH18_02100	COG0513	Belongs to the DEAD box helicase family
MWH18_02110	COG1127	ABC transporter
MWH18_02115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MWH18_02125	COG2854	intermembrane phospholipid transfer
MWH18_02135	COG0598	Magnesium transport protein CorA
MWH18_02145	COG0494	nUDIX hydrolase
MWH18_02150	COG1040	competence protein
MWH18_02155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MWH18_02175	COG1946	Acyl-CoA thioesterase
MWH18_02180	COG1301	dicarboxylic acid transport
MWH18_02195	COG1959	2 iron, 2 sulfur cluster binding
MWH18_02200	COG1017	nitric oxide dioxygenase activity
MWH18_02200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MWH18_02210	COG0433	COG0433 Predicted ATPase
MWH18_02215	COG0626	cystathionine gamma-synthase activity
MWH18_02230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MWH18_02235	COG0088	Forms part of the polypeptide exit tunnel
MWH18_02370	COG1960	acyl-CoA dehydrogenase activity
MWH18_02375	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MWH18_02405	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MWH18_02410	COG0339	signal peptide processing
MWH18_02415	COG0557	exoribonuclease II activity
MWH18_02465	COG0179	Fumarylacetoacetate (FAA) hydrolase
MWH18_02470	COG1295	ribonuclease BN
MWH18_02505	COG1702	phosphate starvation-inducible protein PhoH
MWH18_02515	COG0741	lytic transglycosylase activity
MWH18_02515	COG1196	nuclear chromosome segregation
MWH18_02515	COG0739	heme binding
MWH18_02545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MWH18_02550	COG1183	phosphatidylcholine synthase activity
MWH18_02595	COG1960	acyl-CoA dehydrogenase activity
MWH18_02600	COG1309	transcriptional regulator
MWH18_02615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MWH18_02620	COG1960	acyl-CoA dehydrogenase activity
MWH18_02660	COG2969	positive regulation of protein catabolic process
MWH18_02670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MWH18_02675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MWH18_02680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MWH18_02685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MWH18_02690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MWH18_02710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MWH18_02720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MWH18_02725	COG1408	metallophosphoesterase
MWH18_02730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MWH18_02730	COG2885	chlorophyll binding
MWH18_02735	COG2199	diguanylate cyclase activity
MWH18_02775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MWH18_02795	COG4372	Transposase
MWH18_02820	COG1607	acyl-coa hydrolase
MWH18_02865	COG0613	PHP domain protein
MWH18_02870	COG3781	membrane
MWH18_02880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MWH18_02885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MWH18_02895	COG1862	Preprotein translocase
MWH18_02915	COG0784	Response regulator, receiver
MWH18_02915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MWH18_02915	COG2205	protein histidine kinase activity
MWH18_02915	COG2198	Histidine kinase
MWH18_02920	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MWH18_02935	COG0726	polysaccharide deacetylase
MWH18_02950	COG1216	Glycosyl transferase, family 2
MWH18_03000	COG0625	glutathione transferase activity
MWH18_03005	COG0583	DNA-binding transcription factor activity
MWH18_03010	COG1960	acyl-CoA dehydrogenase activity
MWH18_03015	COG1960	acyl-CoA dehydrogenase activity
MWH18_03025	COG2205	protein histidine kinase activity
MWH18_03030	COG0745	RESPONSE REGULATOR receiver
MWH18_03045	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MWH18_03065	COG2096	Adenosyltransferase
MWH18_03115	COG0285	dihydrofolate synthase activity
MWH18_03135	COG0450	alkyl hydroperoxide reductase
MWH18_03150	COG0477	Major facilitator Superfamily
MWH18_03155	COG1272	protein, Hemolysin III
MWH18_03175	COG2153	protein acetylation
MWH18_03195	COG0183	Belongs to the thiolase family
MWH18_03200	COG2207	Transcriptional regulator
MWH18_03220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MWH18_03240	COG0183	Belongs to the thiolase family
MWH18_03250	COG2885	chlorophyll binding
MWH18_03250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MWH18_03260	COG1690	Belongs to the RtcB family
MWH18_03265	COG0833	amino acid
MWH18_03275	COG2233	PERMEase
MWH18_03280	COG1217	gtp-binding protein TYPA
MWH18_03320	COG2094	Belongs to the DNA glycosylase MPG family
MWH18_03330	COG1902	pentaerythritol trinitrate reductase activity
MWH18_03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MWH18_03350	COG0354	folic acid binding
MWH18_03370	COG2233	PERMEase
MWH18_03375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MWH18_03380	COG0251	oxidation-reduction process
MWH18_03385	COG1335	isochorismatase
MWH18_03390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MWH18_03395	COG0778	Nitroreductase
MWH18_03400	COG0596	Alpha beta hydrolase
MWH18_03405	COG3189	MarR family transcriptional regulator
MWH18_03410	COG2824	Alkylphosphonate utilization operon protein PhnA
MWH18_03415	COG3422	double-strand break repair
MWH18_03460	COG0840	transmembrane signaling receptor activity
MWH18_03480	COG5510	response to toxic substance
MWH18_03490	COG2832	Protein of unknown function (DUF454)
MWH18_03495	COG1376	ErfK ybiS ycfS ynhG family protein
MWH18_03535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MWH18_03545	COG1289	transmembrane transporter activity
MWH18_03550	COG2814	Major facilitator Superfamily
MWH18_03570	COG1115	amino acid carrier protein
MWH18_03575	COG1752	Esterase of the alpha-beta hydrolase superfamily
MWH18_03580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MWH18_03590	COG3590	peptidase
MWH18_03615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MWH18_03625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MWH18_03630	COG1077	Cell shape determining protein MreB Mrl
MWH18_03635	COG1792	Involved in formation and maintenance of cell shape
MWH18_03640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MWH18_03645	COG0424	maF-like protein
MWH18_03650	COG1530	ribonuclease E activity
MWH18_03660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MWH18_03680	COG2249	NAD(P)H dehydrogenase (quinone) activity
MWH18_03705	COG2207	Transcriptional regulator
MWH18_03725	COG0464	growth
MWH18_03790	COG2826	transposase and inactivated derivatives, IS30 family
MWH18_03810	COG0673	inositol 2-dehydrogenase activity
MWH18_03815	COG1324	tolerance protein
MWH18_03840	COG2826	transposase and inactivated derivatives, IS30 family
MWH18_03850	COG0305	Participates in initiation and elongation during chromosome replication
MWH18_03890	COG0582	viral genome integration into host DNA
MWH18_03910	COG3046	protein related to deoxyribodipyrimidine photolyase
MWH18_03920	COG1113	amino acid transport
MWH18_03925	COG2828	Protein conserved in bacteria
MWH18_03930	COG0142	geranyltranstransferase activity
MWH18_03935	COG2315	Protein conserved in bacteria
MWH18_03950	COG1752	Esterase of the alpha-beta hydrolase superfamily
MWH18_03985	COG4372	Transposase
MWH18_03990	COG2194	sulfuric ester hydrolase activity
MWH18_03995	COG0745	RESPONSE REGULATOR receiver
MWH18_04000	COG0642	Histidine kinase
MWH18_04010	COG0004	ammonium transporteR
MWH18_04015	COG0583	DNA-binding transcription factor activity
MWH18_04040	COG0525	valine-tRNA ligase activity
MWH18_04050	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_04060	COG0393	Putative heavy-metal-binding
MWH18_04065	COG0393	Putative heavy-metal-binding
MWH18_04070	COG1538	Outer membrane efflux protein
MWH18_04080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_04085	COG0671	phosphoesterase, PA-phosphatase related
MWH18_04110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MWH18_04125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MWH18_04125	COG1648	precorrin-2 dehydrogenase activity
MWH18_04130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MWH18_04180	COG0531	amino acid
MWH18_04195	COG0321	lipoyl(octanoyl) transferase activity
MWH18_04200	COG2921	Belongs to the UPF0250 family
MWH18_04240	COG2009	succinate dehydrogenase
MWH18_04245	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MWH18_04250	COG1053	succinate dehydrogenase
MWH18_04255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MWH18_04280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MWH18_04310	COG2354	Protein conserved in bacteria
MWH18_04315	COG2321	neutral zinc metallopeptidase
MWH18_04335	COG2843	Capsule synthesis protein
MWH18_04355	COG0589	response to stress
MWH18_04365	COG0251	oxidation-reduction process
MWH18_04370	COG1309	transcriptional regulator
MWH18_04385	COG0505	Belongs to the CarA family
MWH18_04415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MWH18_04420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MWH18_04435	COG3540	Alkaline phosphatase
MWH18_04465	COG0477	Major facilitator Superfamily
MWH18_04470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MWH18_04485	COG1597	lipid kinase activity
MWH18_04490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MWH18_04530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MWH18_04545	COG3620	sequence-specific DNA binding
MWH18_04735	COG0582	viral genome integration into host DNA
MWH18_04750	COG0584	glycerophosphoryl diester phosphodiesterase
MWH18_04770	COG0741	lytic transglycosylase activity
MWH18_04790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MWH18_04795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MWH18_04835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_04845	COG0778	Nitroreductase
MWH18_04850	COG0300	oxidoreductase activity
MWH18_04880	COG0243	molybdopterin cofactor binding
MWH18_04885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MWH18_04890	COG3339	Conserved Protein
MWH18_04915	COG1115	amino acid carrier protein
MWH18_04920	COG1113	amino acid transport
MWH18_04930	COG0019	diaminopimelate decarboxylase activity
MWH18_04940	COG1280	lysine exporter protein (LysE YggA)
MWH18_04945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MWH18_04975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_05010	COG4591	ABC-type transport system involved in lipoprotein release permease component
MWH18_05015	COG1136	(ABC) transporter
MWH18_05020	COG0658	competence protein
MWH18_05020	COG2333	competence protein COMEC
MWH18_05030	COG0616	signal peptide processing
MWH18_05030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MWH18_05035	COG0596	Alpha beta hydrolase
MWH18_05040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MWH18_05050	COG0628	permease
MWH18_05070	COG4372	Transposase
MWH18_05100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MWH18_05120	COG0823	Involved in the tonB-independent uptake of proteins
MWH18_05140	COG0824	Thioesterase
MWH18_05145	COG1473	amidohydrolase
MWH18_05165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MWH18_05165	COG0047	phosphoribosylformylglycinamidine synthase activity
MWH18_05170	COG2814	Major facilitator Superfamily
MWH18_05175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MWH18_05180	COG1024	Enoyl-CoA hydratase
MWH18_05185	COG1056	cytidyltransferase-related domain
MWH18_05185	COG1051	belongs to the nudix hydrolase family
MWH18_05200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MWH18_05215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MWH18_05230	COG4625	pathogenesis
MWH18_05235	COG0583	DNA-binding transcription factor activity
MWH18_05240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MWH18_05245	COG4208	sulfate ABC transporter
MWH18_05250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MWH18_05260	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MWH18_05265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MWH18_05270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MWH18_05290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MWH18_05305	COG0481	GTPase activity
MWH18_05310	COG0681	Belongs to the peptidase S26 family
MWH18_05320	COG0571	ribonuclease III activity
MWH18_05325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MWH18_05335	COG1381	Involved in DNA repair and RecF pathway recombination
MWH18_05340	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MWH18_05350	COG4221	oxidoreductase activity
MWH18_05380	COG0436	Aminotransferase
MWH18_05400	COG0556	nucleotide-excision repair
MWH18_05410	COG2962	Rard protein
MWH18_05455	COG2070	2-Nitropropane dioxygenase
MWH18_05470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MWH18_05485	COG1215	transferase activity, transferring glycosyl groups
MWH18_05500	COG0415	Belongs to the DNA photolyase family
MWH18_05510	COG1252	NADH dehydrogenase
MWH18_05515	COG1686	Belongs to the peptidase S11 family
MWH18_05530	COG1187	pseudouridine synthase activity
MWH18_05545	COG0477	Major facilitator Superfamily
MWH18_05550	COG0583	DNA-binding transcription factor activity
MWH18_05555	COG1823	symporter activity
MWH18_05565	COG0612	Peptidase, M16
MWH18_05600	COG0352	thiamine-phosphate diphosphorylase activity
MWH18_05635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MWH18_05650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MWH18_05655	COG0076	glutamate decarboxylase activity
MWH18_05665	COG1522	sequence-specific DNA binding
MWH18_05670	COG3961	Belongs to the TPP enzyme family
MWH18_05675	COG1113	amino acid transport
MWH18_05680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MWH18_05685	COG0573	inorganic phosphate transmembrane transporter activity
MWH18_05695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MWH18_05700	COG0616	signal peptide processing
MWH18_05740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MWH18_05745	COG1686	Belongs to the peptidase S11 family
MWH18_05770	COG0583	DNA-binding transcription factor activity
MWH18_05775	COG1067	ATP-dependent peptidase activity
MWH18_05780	COG2211	Major facilitator Superfamily
MWH18_05815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MWH18_05820	COG1966	Carbon starvation protein
MWH18_05825	COG2879	small protein
MWH18_05885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MWH18_05890	COG1741	Belongs to the pirin family
MWH18_05905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MWH18_05910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MWH18_05915	COG4605	iron ion homeostasis
MWH18_05920	COG4604	ABC transporter, ATP-binding protein
MWH18_05930	COG4774	siderophore transport
MWH18_05940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MWH18_05945	COG1021	2,3-dihydroxybenzoate-AMP ligase
MWH18_05950	COG1535	isochorismatase
MWH18_05950	COG3433	isochorismatase activity
MWH18_05960	COG1132	(ABC) transporter
MWH18_05965	COG1132	(ABC) transporter
MWH18_05970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MWH18_05980	COG1169	isochorismate synthase
MWH18_05995	COG3739	integral membrane protein
MWH18_06015	COG0302	gtp cyclohydrolase
MWH18_06025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MWH18_06035	COG2840	Smr protein MutS2
MWH18_06055	COG0308	aminopeptidase N
MWH18_06060	COG0512	Glutamine amidotransferase of anthranilate synthase
MWH18_06330	COG1598	PFAM Uncharacterised protein family UPF0150
MWH18_06340	COG1196	nuclear chromosome segregation
MWH18_06340	COG0739	heme binding
MWH18_06340	COG0741	lytic transglycosylase activity
MWH18_06440	COG0582	viral genome integration into host DNA
MWH18_06455	COG0174	glutamine synthetase
MWH18_06465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MWH18_06500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MWH18_06505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MWH18_06510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MWH18_06530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MWH18_06535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MWH18_06540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MWH18_06555	COG1960	acyl-CoA dehydrogenase activity
MWH18_06560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MWH18_06565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MWH18_06575	COG2223	nitrite transmembrane transporter activity
MWH18_06585	COG0024	Methionine aminopeptidase
MWH18_06590	COG0052	Belongs to the universal ribosomal protein uS2 family
MWH18_06605	COG2207	Transcriptional regulator
MWH18_06630	COG2951	lytic endotransglycosylase activity
MWH18_06635	COG0772	Belongs to the SEDS family
MWH18_06650	COG0842	Transport permease protein
MWH18_06655	COG1131	(ABC) transporter
MWH18_06735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_06745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MWH18_06750	COG4215	(ABC) transporter
MWH18_06755	COG4160	amino acid transport
MWH18_06760	COG4598	ABC transporter
MWH18_06770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MWH18_06775	COG0826	peptidase U32
MWH18_06780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MWH18_06785	COG0384	phenazine biosynthesis protein PhzF
MWH18_06795	COG1720	tRNA m6t6A37 methyltransferase activity
MWH18_06805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MWH18_06820	COG0642	Histidine kinase
MWH18_06830	COG0494	nUDIX hydrolase
MWH18_06840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MWH18_06845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MWH18_06850	COG3139	Protein of unknown function (DUF1315)
MWH18_06855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MWH18_06860	COG1301	dicarboxylic acid transport
MWH18_06865	COG1960	acyl-CoA dehydrogenase activity
MWH18_06880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MWH18_06890	COG2195	Cleaves the N-terminal amino acid of tripeptides
MWH18_06910	COG1690	Belongs to the RtcB family
MWH18_06915	COG1234	tRNA 3'-trailer cleavage
MWH18_06920	COG4650	regulator
MWH18_06950	COG2363	Small membrane protein
MWH18_06975	COG0513	Belongs to the DEAD box helicase family
MWH18_06985	COG0778	Nitroreductase
MWH18_07015	COG1286	toxin biosynthetic process
MWH18_07040	COG4783	chaperone-mediated protein folding
MWH18_07045	COG1610	YqeY-like protein
MWH18_07075	COG0515	serine threonine protein kinase
MWH18_07075	COG2815	serine threonine protein kinase
MWH18_07100	COG1278	Cold shock
MWH18_07115	COG3243	poly(R)-hydroxyalkanoic acid synthase
MWH18_07120	COG0786	glutamate:sodium symporter activity
MWH18_07125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MWH18_07125	COG0475	glutathione-regulated potassium exporter activity
MWH18_07205	COG1309	transcriptional regulator
MWH18_07215	COG2985	domain, Protein
MWH18_07225	COG2995	paraquat-inducible protein a
MWH18_07230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MWH18_07230	COG3008	intermembrane lipid transfer
MWH18_07240	COG2351	hydroxyisourate hydrolase activity
MWH18_07280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MWH18_07290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MWH18_07295	COG0642	Histidine kinase
MWH18_07300	COG0745	RESPONSE REGULATOR receiver
MWH18_07320	COG1794	racemase activity, acting on amino acids and derivatives
MWH18_07330	COG2175	clavaminate synthase activity
MWH18_07335	COG3246	L-lysine catabolic process to acetate
MWH18_07340	COG2814	Major facilitator Superfamily
MWH18_07355	COG2855	membrane
MWH18_07405	COG1301	dicarboxylic acid transport
MWH18_07415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MWH18_07420	COG2011	ABC-type metal ion transport system permease component
MWH18_07425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MWH18_07435	COG0151	Belongs to the GarS family
MWH18_07445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MWH18_07475	COG2308	Evidence 4 Homologs of previously reported genes of
MWH18_07485	COG1305	Transglutaminase-like
MWH18_07495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MWH18_07500	COG0305	Participates in initiation and elongation during chromosome replication
MWH18_07525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MWH18_07530	COG1845	cytochrome c oxidase, subunit III
MWH18_07535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MWH18_07565	COG0726	polysaccharide deacetylase
MWH18_07565	COG1649	PFAM Uncharacterised BCR, COG1649
MWH18_07570	COG1215	transferase activity, transferring glycosyl groups
MWH18_07575	COG3658	cytochrome
MWH18_07585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MWH18_07605	COG2890	protein-(glutamine-N5) methyltransferase activity
MWH18_07610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MWH18_07615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MWH18_07630	COG1960	acyl-CoA dehydrogenase activity
MWH18_07635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MWH18_07650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MWH18_07660	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MWH18_07665	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MWH18_07675	COG2205	protein histidine kinase activity
MWH18_07680	COG0745	RESPONSE REGULATOR receiver
MWH18_07685	COG0174	glutamine synthetase
MWH18_07700	COG0477	Major facilitator Superfamily
MWH18_07705	COG0729	surface antigen
MWH18_07735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MWH18_07740	COG2814	Major facilitator Superfamily
MWH18_07840	COG2369	cell adhesion
MWH18_07845	COG4383	Mu-like prophage protein gp29
MWH18_07860	COG4373	Mu-like prophage FluMu protein gp28
MWH18_07895	COG0681	Belongs to the peptidase S26 family
MWH18_07925	COG3409	Peptidoglycan-binding domain 1 protein
MWH18_07925	COG3267	Type II secretory pathway component ExeA
MWH18_07995	COG0583	DNA-binding transcription factor activity
MWH18_08010	COG1187	pseudouridine synthase activity
MWH18_08030	COG0802	atpase or kinase
MWH18_08035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MWH18_08045	COG1923	regulation of RNA biosynthetic process
MWH18_08050	COG0697	spore germination
MWH18_08065	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MWH18_08075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MWH18_08080	COG0519	Catalyzes the synthesis of GMP from XMP
MWH18_08080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MWH18_08085	COG4302	ethanolamine ammonia-lyase activity
MWH18_08090	COG4303	Ethanolamine ammonia lyase large subunit
MWH18_08095	COG0531	amino acid
MWH18_08115	COG1454	alcohol dehydrogenase
MWH18_08120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MWH18_08145	COG0308	aminopeptidase N
MWH18_08185	COG1605	Chorismate mutase
MWH18_08200	COG4772	TonB-dependent receptor
MWH18_08205	COG4774	siderophore transport
MWH18_08260	COG3772	lysozyme
MWH18_08285	COG0583	DNA-binding transcription factor activity
MWH18_08290	COG4372	Transposase
MWH18_08340	COG0488	(ABC) transporter
MWH18_08345	COG0589	response to stress
MWH18_08365	COG3135	benzoate transporter
MWH18_08370	COG1522	sequence-specific DNA binding
MWH18_08380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MWH18_08385	COG0583	DNA-binding transcription factor activity
MWH18_08395	COG0183	Belongs to the thiolase family
MWH18_08400	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_08405	COG2030	dehydratase
MWH18_08435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MWH18_08450	COG0824	Thioesterase
MWH18_08455	COG1454	alcohol dehydrogenase
MWH18_08480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MWH18_08515	COG0069	glutamate synthase activity
MWH18_08900	COG2194	sulfuric ester hydrolase activity
MWH18_08905	COG2814	Major facilitator Superfamily
MWH18_08920	COG0511	ligase activity, forming carbon-carbon bonds
MWH18_08945	COG4264	IucA IucC family
MWH18_08955	COG4264	IucA IucC family
MWH18_08960	COG2423	ornithine cyclodeaminase activity
MWH18_08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MWH18_08975	COG1116	anion transmembrane transporter activity
MWH18_08975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MWH18_08990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MWH18_08990	COG2146	nitrite reductase [NAD(P)H] activity
MWH18_08995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MWH18_09000	COG0243	molybdopterin cofactor binding
MWH18_09010	COG0243	molybdopterin cofactor binding
MWH18_09015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MWH18_09030	COG0315	cyclic pyranopterin monophosphate synthase activity
MWH18_09030	COG0521	Mo-molybdopterin cofactor biosynthetic process
MWH18_09035	COG0303	'Molybdopterin
MWH18_09045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MWH18_09050	COG0697	spore germination
MWH18_09075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MWH18_09100	COG4372	Transposase
MWH18_09120	COG4372	Transposase
MWH18_09125	COG0596	Alpha beta hydrolase
MWH18_09190	COG2204	response regulator
MWH18_09195	COG3852	Histidine kinase
MWH18_09220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MWH18_09225	COG0575	Belongs to the CDS family
MWH18_09260	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MWH18_09275	COG2137	regulation of response to DNA damage stimulus
MWH18_09285	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MWH18_09290	COG1011	Hydrolase
MWH18_09305	COG1522	sequence-specific DNA binding
MWH18_09315	COG1113	amino acid transport
MWH18_09330	COG0659	secondary active sulfate transmembrane transporter activity
MWH18_09350	COG3300	MHYT domain
MWH18_09350	COG5001	Diguanylate cyclase
MWH18_09365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MWH18_09365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MWH18_09365	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MWH18_09370	COG1105	Belongs to the carbohydrate kinase PfkB family
MWH18_09375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MWH18_09375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MWH18_09395	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MWH18_09405	COG0024	Methionine aminopeptidase
MWH18_09410	COG0583	DNA-binding transcription factor activity
MWH18_09420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MWH18_09425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MWH18_09430	COG0516	GMP reductase activity
MWH18_09430	COG0517	IMP dehydrogenase activity
MWH18_09455	COG0552	protein localization to endoplasmic reticulum
MWH18_09480	COG4890	Cyd operon protein YbgT
MWH18_09485	COG1294	oxidase, subunit
MWH18_09500	COG1585	Membrane protein implicated in regulation of membrane protease activity
MWH18_09510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MWH18_09525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MWH18_09530	COG0569	domain protein
MWH18_09535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MWH18_09565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MWH18_09570	COG0542	response to heat
MWH18_09595	COG0446	pyridine nucleotide-disulphide oxidoreductase
MWH18_09595	COG1902	pentaerythritol trinitrate reductase activity
MWH18_09635	COG0148	phosphopyruvate hydratase activity
MWH18_09655	COG4372	Transposase
MWH18_09670	COG4773	Receptor
MWH18_09675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MWH18_09685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MWH18_09690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MWH18_09695	COG0183	Belongs to the thiolase family
MWH18_09700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MWH18_09705	COG0596	Alpha beta hydrolase
MWH18_09710	COG2271	Major facilitator Superfamily
MWH18_09715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MWH18_09720	COG3485	protocatechuate 3,4-dioxygenase
MWH18_09725	COG3485	protocatechuate 3,4-dioxygenase
MWH18_09730	COG0710	3-dehydroquinate dehydratase activity
MWH18_09735	COG3420	alginic acid biosynthetic process
MWH18_09745	COG4993	Dehydrogenase
MWH18_09755	COG2391	methyltransferase activity
MWH18_09770	COG1414	Transcriptional regulator
MWH18_09775	COG0583	DNA-binding transcription factor activity
MWH18_09780	COG1960	acyl-CoA dehydrogenase activity
MWH18_09805	COG2814	Major facilitator Superfamily
MWH18_09815	COG0154	amidase activity
MWH18_09835	COG4638	Rieske (2fe-2S)
MWH18_09845	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_09855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MWH18_09865	COG3733	amine oxidase
MWH18_09875	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_09880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MWH18_09885	COG0183	Belongs to the thiolase family
MWH18_09890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MWH18_09895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MWH18_09905	COG4829	muconolactone delta-isomerase
MWH18_09910	COG4948	Mandelate Racemase Muconate Lactonizing
MWH18_09915	COG0583	DNA-binding transcription factor activity
MWH18_09925	COG2186	Transcriptional regulator
MWH18_09945	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_09950	COG2351	hydroxyisourate hydrolase activity
MWH18_09955	COG2233	PERMEase
MWH18_09965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MWH18_09970	COG2186	Transcriptional regulator
MWH18_09980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MWH18_09990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MWH18_10010	COG0446	pyridine nucleotide-disulphide oxidoreductase
MWH18_10010	COG1902	pentaerythritol trinitrate reductase activity
MWH18_10015	COG4221	oxidoreductase activity
MWH18_10050	COG1309	transcriptional regulator
MWH18_10055	COG0583	DNA-binding transcription factor activity
MWH18_10065	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_10070	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_10080	COG1960	acyl-CoA dehydrogenase activity
MWH18_10090	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_10120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MWH18_10125	COG2259	Doxx family
MWH18_10135	COG0583	DNA-binding transcription factor activity
MWH18_10145	COG4993	Dehydrogenase
MWH18_10180	COG0583	DNA-binding transcription factor activity
MWH18_10205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MWH18_10210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MWH18_10230	COG2831	hemolysin activation secretion protein
MWH18_10240	COG4372	Transposase
MWH18_10310	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_10335	COG0583	DNA-binding transcription factor activity
MWH18_10340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MWH18_10350	COG2084	Dehydrogenase
MWH18_10365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MWH18_10370	COG1120	ATPase activity
MWH18_10385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MWH18_10420	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MWH18_10460	COG1073	alpha beta
MWH18_10470	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_10485	COG2207	Transcriptional regulator
MWH18_10505	COG3539	Fimbrial protein
MWH18_10530	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MWH18_10540	COG0753	catalase activity
MWH18_10570	COG2205	protein histidine kinase activity
MWH18_10575	COG0745	RESPONSE REGULATOR receiver
MWH18_10580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_10585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MWH18_10640	COG1535	isochorismatase
MWH18_10640	COG3433	isochorismatase activity
MWH18_10645	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_10650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MWH18_10655	COG4149	molybdate abc transporter
MWH18_10660	COG0725	ABC transporter, periplasmic molybdate-binding protein
MWH18_10670	COG4638	Rieske (2fe-2S)
MWH18_10675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MWH18_10680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MWH18_10680	COG0543	2 iron, 2 sulfur cluster binding
MWH18_10695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MWH18_10705	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_10725	COG2207	Transcriptional regulator
MWH18_10730	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_10735	COG2610	gluconate transmembrane transporter activity
MWH18_10750	COG0583	DNA-binding transcription factor activity
MWH18_10765	COG2031	fatty acid transporter
MWH18_10770	COG0183	Belongs to the thiolase family
MWH18_10775	COG0583	DNA-binding transcription factor activity
MWH18_10780	COG0583	DNA-binding transcription factor activity
MWH18_10795	COG1027	Aspartate ammonia-lyase
MWH18_10805	COG0477	Major facilitator Superfamily
MWH18_10815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MWH18_10820	COG1733	regulation of RNA biosynthetic process
MWH18_10825	COG2207	Transcriptional regulator
MWH18_10825	COG3708	Transcriptional regulator
MWH18_10840	COG0730	response to heat
MWH18_10865	COG3781	membrane
MWH18_10870	COG1063	alcohol dehydrogenase
MWH18_10880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MWH18_10885	COG0508	dehydrogenase complex catalyzes the overall conversion of
MWH18_10890	COG0022	dehydrogenase e1 component
MWH18_10895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MWH18_10900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MWH18_10940	COG0133	tryptophan synthase activity
MWH18_10950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MWH18_10980	COG0583	DNA-binding transcription factor activity
MWH18_10985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MWH18_10995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MWH18_11055	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MWH18_11060	COG4773	Receptor
MWH18_11085	COG0730	response to heat
MWH18_11090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MWH18_11110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MWH18_11125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MWH18_11135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MWH18_11150	COG1960	acyl-CoA dehydrogenase activity
MWH18_11155	COG1960	acyl-CoA dehydrogenase activity
MWH18_11160	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MWH18_11165	COG2207	Transcriptional regulator
MWH18_11170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MWH18_11175	COG0776	regulation of translation
MWH18_11200	COG0822	iron-sulfur transferase activity
MWH18_11205	COG0316	Belongs to the HesB IscA family
MWH18_11235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MWH18_11255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MWH18_11260	COG0702	epimerase
MWH18_11290	COG4172	Belongs to the ABC transporter superfamily
MWH18_11300	COG0601	transmembrane transport
MWH18_11305	COG0339	signal peptide processing
MWH18_11310	COG4166	transmembrane transport
MWH18_11355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MWH18_11360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MWH18_11375	COG2431	L-lysine efflux transmembrane transporter activity
MWH18_11390	COG0776	regulation of translation
MWH18_11455	COG0084	hydrolase, TatD family'
MWH18_11475	COG1663	tetraacyldisaccharide 4'-kinase activity
MWH18_11480	COG1132	(ABC) transporter
MWH18_11490	COG0811	peptide transport
MWH18_11495	COG1475	DNA binding
MWH18_11500	COG1192	Involved in chromosome partitioning
MWH18_11510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MWH18_11515	COG3178	'Phosphotransferase
MWH18_11525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MWH18_11550	COG0424	maF-like protein
MWH18_11555	COG2850	peptidyl-arginine hydroxylation
MWH18_11565	COG0640	Transcriptional regulator
MWH18_11575	COG3619	membrane
MWH18_11580	COG3122	Protein conserved in bacteria
MWH18_11585	COG1132	(ABC) transporter
MWH18_11605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MWH18_11610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MWH18_11620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MWH18_11620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MWH18_11620	COG0506	proline dehydrogenase activity
MWH18_11625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MWH18_11640	COG3698	Phosphodiester glycosidase
MWH18_11650	COG2353	YceI-like domain
MWH18_11660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MWH18_11705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MWH18_11705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MWH18_11730	COG3539	Fimbrial protein
MWH18_11765	COG0583	DNA-binding transcription factor activity
MWH18_11770	COG0697	spore germination
MWH18_11780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MWH18_11785	COG4372	Transposase
MWH18_11805	COG0583	DNA-binding transcription factor activity
MWH18_11820	COG1309	transcriptional regulator
MWH18_11835	COG1522	sequence-specific DNA binding
MWH18_11845	COG1126	abc transporter atp-binding protein
MWH18_11850	COG0765	amino acid transport
MWH18_11855	COG0765	amino acid transport
MWH18_11885	COG1464	Belongs to the NlpA lipoprotein family
MWH18_11895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MWH18_11900	COG2011	ABC-type metal ion transport system permease component
MWH18_11905	COG0012	GTP binding
MWH18_11930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MWH18_11965	COG2207	Transcriptional regulator
MWH18_11965	COG1917	Cupin 2, conserved barrel domain protein
MWH18_11970	COG0386	Belongs to the glutathione peroxidase family
MWH18_11980	COG0436	Aminotransferase
MWH18_11985	COG1301	dicarboxylic acid transport
MWH18_12020	COG3634	alkyl hydroperoxide reductase activity
MWH18_12035	COG0583	DNA-binding transcription factor activity
MWH18_12040	COG0431	NADPH-dependent FMN reductase
MWH18_12045	COG0798	PFAM Bile acid sodium symporter
MWH18_12055	COG0640	Transcriptional regulator
MWH18_12070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MWH18_12080	COG0583	DNA-binding transcription factor activity
MWH18_12090	COG1953	Uracil, thiamine, allantoin
MWH18_12100	COG2175	clavaminate synthase activity
MWH18_12105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MWH18_12110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MWH18_12115	COG4521	taurine ABC transporter
MWH18_12125	COG0477	Major facilitator Superfamily
MWH18_12145	COG1271	oxidase subunit
MWH18_12150	COG1294	oxidase, subunit
MWH18_12160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MWH18_12180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MWH18_12200	COG3052	prosthetic group binding
MWH18_12205	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
MWH18_12230	COG1346	cytolysis
MWH18_12240	COG0583	DNA-binding transcription factor activity
MWH18_12245	COG0625	glutathione transferase activity
MWH18_12250	COG0625	glutathione transferase activity
MWH18_12270	COG0583	DNA-binding transcription factor activity
MWH18_12275	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_12285	COG1045	serine acetyltransferase
MWH18_12290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MWH18_12295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MWH18_12305	COG1280	lysine exporter protein (LysE YggA)
MWH18_12315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MWH18_12320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MWH18_12330	COG0765	amino acid transport
MWH18_12355	COG0784	Response regulator, receiver
MWH18_12355	COG2205	protein histidine kinase activity
MWH18_12400	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_12450	COG0583	DNA-binding transcription factor activity
MWH18_12460	COG2814	Major facilitator Superfamily
MWH18_12475	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_12480	COG1309	transcriptional regulator
MWH18_12485	COG1960	acyl-CoA dehydrogenase activity
MWH18_12490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MWH18_12495	COG1024	Enoyl-CoA hydratase
MWH18_12500	COG4770	biotin carboxylase activity
MWH18_12510	COG0583	DNA-binding transcription factor activity
MWH18_12525	COG1960	acyl-CoA dehydrogenase activity
MWH18_12535	COG2814	Major facilitator Superfamily
MWH18_12545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MWH18_12550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MWH18_12555	COG2814	Major facilitator Superfamily
MWH18_12560	COG1960	acyl-CoA dehydrogenase activity
MWH18_12565	COG1024	Enoyl-CoA hydratase
MWH18_12570	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_12575	COG1250	3-hydroxyacyl-CoA dehydrogenase
MWH18_12580	COG0183	Belongs to the thiolase family
MWH18_12590	COG2814	Major facilitator Superfamily
MWH18_12600	COG1024	Enoyl-CoA hydratase
MWH18_12615	COG1960	acyl-CoA dehydrogenase activity
MWH18_12620	COG2814	Major facilitator Superfamily
MWH18_12625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MWH18_12630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MWH18_12645	COG3842	ATPase activity
MWH18_12650	COG1840	ABC-type Fe3 transport system, periplasmic component
MWH18_12665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MWH18_12670	COG1414	Transcriptional regulator
MWH18_12680	COG0583	DNA-binding transcription factor activity
MWH18_12715	COG2050	protein possibly involved in aromatic compounds catabolism
MWH18_12725	COG3327	negative regulation of DNA-templated transcription, initiation
MWH18_12730	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MWH18_12735	COG0183	Belongs to the thiolase family
MWH18_12740	COG1250	3-hydroxyacyl-CoA dehydrogenase
MWH18_12745	COG1024	Enoyl-CoA hydratase
MWH18_12755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MWH18_12760	COG2151	metal-sulfur cluster biosynthetic enzyme
MWH18_12765	COG3396	Phenylacetate-CoA oxygenase
MWH18_12770	COG3460	Phenylacetate-CoA oxygenase
MWH18_12775	COG3396	Phenylacetate-CoA oxygenase
MWH18_12780	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_12780	COG2030	dehydratase
MWH18_12785	COG1760	l-serine dehydratase
MWH18_12800	COG0789	Transcriptional regulator
MWH18_12810	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MWH18_12835	COG0590	tRNA wobble adenosine to inosine editing
MWH18_12840	COG0666	response to abiotic stimulus
MWH18_12940	COG1116	anion transmembrane transporter activity
MWH18_12945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MWH18_12955	COG0864	Transcriptional regulator
MWH18_12965	COG1733	regulation of RNA biosynthetic process
MWH18_12970	COG2249	NAD(P)H dehydrogenase (quinone) activity
MWH18_12975	COG0439	Biotin carboxylase
MWH18_12990	COG1063	alcohol dehydrogenase
MWH18_12995	COG1250	3-hydroxyacyl-CoA dehydrogenase
MWH18_13030	COG3210	domain, Protein
MWH18_13035	COG2831	hemolysin activation secretion protein
MWH18_13040	COG0038	chloride channel
MWH18_13045	COG4770	biotin carboxylase activity
MWH18_13065	COG1914	H( )-stimulated, divalent metal cation uptake system
MWH18_13070	COG0583	DNA-binding transcription factor activity
MWH18_13080	COG1595	DNA-templated transcription, initiation
MWH18_13090	COG3220	belongs to the UPF0276 family
MWH18_13140	COG0702	epimerase
MWH18_13145	COG1733	regulation of RNA biosynthetic process
MWH18_13160	COG1051	belongs to the nudix hydrolase family
MWH18_13200	COG3038	cytochrome b561
MWH18_13205	COG0753	catalase activity
MWH18_13220	COG1469	GTP cyclohydrolase I activity
MWH18_13225	COG4451	ribulose bisphosphate carboxylase, small
MWH18_13225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MWH18_13230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MWH18_13245	COG1522	sequence-specific DNA binding
MWH18_13250	COG0531	amino acid
MWH18_13255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MWH18_13270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MWH18_13285	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MWH18_13295	COG4122	O-methyltransferase activity
MWH18_13325	COG1538	Outer membrane efflux protein
MWH18_13335	COG1137	ATPase activity
MWH18_13340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MWH18_13350	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MWH18_13490	COG3728	DNA packaging
MWH18_13490	COG5484	DNA packaging
MWH18_13570	COG5377	YqaJ viral recombinase family
MWH18_13580	COG0210	DNA helicase
MWH18_13665	COG2814	Major facilitator Superfamily
MWH18_13675	COG0668	transmembrane transport
MWH18_13750	COG2226	methyltransferase
MWH18_13775	COG1278	Cold shock
MWH18_13780	COG1560	Kdo2-lipid A biosynthetic process
MWH18_13785	COG1280	lysine exporter protein (LysE YggA)
MWH18_13820	COG1570	exodeoxyribonuclease VII activity
MWH18_13870	COG0583	DNA-binding transcription factor activity
MWH18_13880	COG4638	Rieske (2fe-2S)
MWH18_13890	COG0543	2 iron, 2 sulfur cluster binding
MWH18_13890	COG0633	Ferredoxin
MWH18_13895	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_13900	COG3135	benzoate transporter
MWH18_13905	COG2814	Major facilitator Superfamily
MWH18_13920	COG1643	Atp-dependent helicase
MWH18_13945	COG3634	alkyl hydroperoxide reductase activity
MWH18_13965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MWH18_13970	COG0625	glutathione transferase activity
MWH18_13980	COG2885	chlorophyll binding
MWH18_14015	COG0542	response to heat
MWH18_14030	COG1765	OsmC-like protein
MWH18_14045	COG0667	Aldo Keto reductase
MWH18_14060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MWH18_14075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MWH18_14085	COG0527	aspartate kinase activity
MWH18_14095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MWH18_14105	COG3038	cytochrome b561
MWH18_14110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MWH18_14115	COG2252	PERMEase
MWH18_14125	COG1741	Belongs to the pirin family
MWH18_14130	COG1309	transcriptional regulator
MWH18_14145	COG2072	flavoprotein involved in K transport
MWH18_14150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MWH18_14155	COG0583	DNA-binding transcription factor activity
MWH18_14170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MWH18_14200	COG1944	ATP diphosphatase activity
MWH18_14220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MWH18_14235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MWH18_14250	COG2814	Major facilitator Superfamily
MWH18_14255	COG1024	Enoyl-CoA hydratase
MWH18_14260	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_14270	COG1960	acyl-CoA dehydrogenase activity
MWH18_14295	COG2186	Transcriptional regulator
MWH18_14300	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_14310	COG4948	Mandelate Racemase Muconate Lactonizing
MWH18_14315	COG2271	Major facilitator Superfamily
MWH18_14320	COG2721	sulfolactate sulfo-lyase activity
MWH18_14325	COG0697	spore germination
MWH18_14345	COG3210	domain, Protein
MWH18_14350	COG2831	hemolysin activation secretion protein
MWH18_14355	COG1113	amino acid transport
MWH18_14375	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_14395	COG0531	amino acid
MWH18_14405	COG1113	amino acid transport
MWH18_14440	COG4269	membrane
MWH18_14455	COG0582	viral genome integration into host DNA
MWH18_14555	COG1902	pentaerythritol trinitrate reductase activity
MWH18_14555	COG0446	pyridine nucleotide-disulphide oxidoreductase
MWH18_14565	COG3706	GGDEF domain
MWH18_14565	COG4251	negative regulation of phosphorylation
MWH18_14565	COG5001	Diguanylate cyclase
MWH18_14565	COG2203	Gaf domain
MWH18_14575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MWH18_14595	COG4172	Belongs to the ABC transporter superfamily
MWH18_14600	COG4239	(ABC) transporter, permease
MWH18_14605	COG4174	ABC transporter (Permease)
MWH18_14610	COG4166	transmembrane transport
MWH18_14615	COG0741	lytic transglycosylase activity
MWH18_14615	COG1388	LysM domain
MWH18_14615	COG0741	lytic transglycosylase activity
MWH18_14615	COG1388	LysM domain
MWH18_14660	COG0583	DNA-binding transcription factor activity
MWH18_14665	COG1279	arginine transmembrane transporter activity
MWH18_14685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MWH18_14690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MWH18_14695	COG0006	proline dipeptidase activity
MWH18_14735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MWH18_14750	COG3384	dioxygenase
MWH18_14760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MWH18_14765	COG2878	Part of a membrane complex involved in electron transport
MWH18_14770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MWH18_14795	COG0768	penicillin binding
MWH18_14800	COG0742	ribosomal rna small subunit methyltransferase
MWH18_14815	COG0830	nickel cation binding
MWH18_14825	COG0804	urea catabolic process
MWH18_14850	COG3015	lipoprotein NlpE involved in copper resistance
MWH18_14865	COG1253	flavin adenine dinucleotide binding
MWH18_14870	COG2851	Citrate transporter
MWH18_14925	COG1773	rubredoxin
MWH18_14930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MWH18_14935	COG0596	Alpha beta hydrolase
MWH18_14940	COG0583	DNA-binding transcription factor activity
MWH18_14970	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MWH18_14975	COG4181	ATPase activity
MWH18_15020	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MWH18_15040	COG0306	phosphate transporter
MWH18_15055	COG3958	Transketolase
MWH18_15060	COG3959	Transketolase, thiamine diphosphate binding domain
MWH18_15065	COG2271	Major facilitator Superfamily
MWH18_15070	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_15075	COG0583	DNA-binding transcription factor activity
MWH18_15090	COG2223	nitrite transmembrane transporter activity
MWH18_15095	COG2207	Transcriptional regulator
MWH18_15100	COG2066	Belongs to the glutaminase family
MWH18_15105	COG0242	peptide deformylase activity
MWH18_15110	COG0477	Major facilitator Superfamily
MWH18_15120	COG0028	Belongs to the TPP enzyme family
MWH18_15135	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_15140	COG2267	carboxylic ester hydrolase activity
MWH18_15150	COG2271	Major facilitator Superfamily
MWH18_15165	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_15185	COG1414	Transcriptional regulator
MWH18_15200	COG1024	Enoyl-CoA hydratase
MWH18_15210	COG1215	transferase activity, transferring glycosyl groups
MWH18_15215	COG0726	polysaccharide deacetylase
MWH18_15215	COG1649	PFAM Uncharacterised BCR, COG1649
MWH18_15225	COG4681	YaeQ
MWH18_15235	COG0523	cobalamin synthesis protein
MWH18_15245	COG1607	acyl-coa hydrolase
MWH18_15255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MWH18_15260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MWH18_15265	COG1309	transcriptional regulator
MWH18_15295	COG0405	Gamma-glutamyltransferase
MWH18_15300	COG2814	Major facilitator Superfamily
MWH18_15310	COG2050	protein possibly involved in aromatic compounds catabolism
MWH18_15325	COG1090	epimerase
MWH18_15345	COG0420	3'-5' exonuclease activity
MWH18_15370	COG0735	belongs to the Fur family
MWH18_15375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MWH18_15380	COG2914	Belongs to the UPF0125 (RnfH) family
MWH18_15395	COG0121	glutamine amidotransferase
MWH18_15410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MWH18_15420	COG0210	DNA helicase
MWH18_15425	COG2885	chlorophyll binding
MWH18_15430	COG0204	Acyl-transferase
MWH18_15445	COG2894	cell division
MWH18_15460	COG1280	lysine exporter protein (LysE YggA)
MWH18_15465	COG1674	ftsk spoiiie
MWH18_15470	COG0492	ferredoxin-NADP+ reductase activity
MWH18_15475	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MWH18_15485	COG0456	acetyltransferase
MWH18_15510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MWH18_15515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MWH18_15525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MWH18_15540	COG1981	membrane
MWH18_15550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MWH18_15550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MWH18_15570	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_15575	COG4638	Rieske (2fe-2S)
MWH18_15580	COG0657	acetylesterase activity
MWH18_15590	COG0473	3-isopropylmalate dehydrogenase activity
MWH18_15595	COG0583	DNA-binding transcription factor activity
MWH18_15615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MWH18_15625	COG0582	viral genome integration into host DNA
MWH18_16000	COG0358	DNA primase activity
MWH18_16015	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MWH18_16045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MWH18_16075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MWH18_16085	COG0351	phosphomethylpyrimidine kinase
MWH18_16085	COG0352	thiamine-phosphate diphosphorylase activity
MWH18_16085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MWH18_16090	COG1652	LysM domain
MWH18_16115	COG1399	metal-binding, possibly nucleic acid-binding protein
MWH18_16120	COG3101	peptidyl-lysine hydroxylation
MWH18_16125	COG0009	L-threonylcarbamoyladenylate synthase
MWH18_16130	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MWH18_16135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MWH18_16150	COG4106	trans-aconitate 2-methyltransferase activity
MWH18_16165	COG2226	methyltransferase
MWH18_16165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MWH18_16165	COG0596	Alpha beta hydrolase
MWH18_16175	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MWH18_16180	COG2223	nitrite transmembrane transporter activity
MWH18_16215	COG4372	Transposase
MWH18_16255	COG4372	Transposase
MWH18_16265	COG3621	Patatin-like phospholipase
MWH18_16285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MWH18_16295	COG1061	Type III restriction enzyme res subunit
MWH18_16300	COG1002	Type II restriction enzyme, methylase subunits
MWH18_16305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MWH18_16320	COG1196	nuclear chromosome segregation
MWH18_16330	COG0730	response to heat
MWH18_16345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MWH18_16355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MWH18_16370	COG4372	Transposase
MWH18_16415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MWH18_16420	COG0489	protein tyrosine kinase activity
MWH18_16430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MWH18_16430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MWH18_16465	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MWH18_16470	COG2081	HI0933 family
MWH18_16480	COG0668	transmembrane transport
MWH18_16500	COG0583	DNA-binding transcription factor activity
MWH18_16520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MWH18_16525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MWH18_16555	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MWH18_16580	COG2199	diguanylate cyclase activity
MWH18_16595	COG0745	RESPONSE REGULATOR receiver
MWH18_16615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MWH18_16620	COG0384	phenazine biosynthesis protein PhzF
MWH18_16675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MWH18_16690	COG0583	DNA-binding transcription factor activity
MWH18_16740	COG0583	DNA-binding transcription factor activity
MWH18_16755	COG0583	DNA-binding transcription factor activity
MWH18_16760	COG1053	succinate dehydrogenase
MWH18_16775	COG1309	transcriptional regulator
MWH18_16785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MWH18_16790	COG2814	Major facilitator Superfamily
MWH18_16795	COG1960	acyl-CoA dehydrogenase activity
MWH18_16800	COG0583	DNA-binding transcription factor activity
MWH18_16805	COG1063	alcohol dehydrogenase
MWH18_16820	COG0582	viral genome integration into host DNA
MWH18_16825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MWH18_16850	COG1122	ATPase activity
MWH18_16995	COG0860	N-Acetylmuramoyl-L-alanine amidase
MWH18_16995	COG3409	Peptidoglycan-binding domain 1 protein
MWH18_17040	COG4695	Portal protein
MWH18_17080	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MWH18_17085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MWH18_17090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MWH18_17110	COG2132	Multicopper oxidase
MWH18_17120	COG0561	phosphatase activity
MWH18_17125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MWH18_17135	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MWH18_17150	COG1214	PFAM Peptidase M22, glycoprotease
MWH18_17210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MWH18_17215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MWH18_17220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MWH18_17280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MWH18_17290	COG1846	Transcriptional regulator
MWH18_17295	COG1764	response to oxidative stress
MWH18_17335	COG0037	tRNA processing
MWH18_17345	COG0248	Ppx GppA phosphatase
MWH18_17375	COG0072	phenylalanine-tRNA ligase activity
MWH18_17405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MWH18_17420	COG1238	metal cluster binding
MWH18_17425	COG0625	glutathione transferase activity
MWH18_17440	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_17445	COG3028	Belongs to the UPF0307 family
MWH18_17450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MWH18_17470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MWH18_17475	COG0617	tRNA 3'-terminal CCA addition
MWH18_17480	COG1555	photosystem II stabilization
MWH18_17485	COG3956	TIGRFAM MazG family protein
MWH18_17495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MWH18_17510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MWH18_17515	COG0784	Response regulator, receiver
MWH18_17515	COG5002	protein histidine kinase activity
MWH18_17515	COG2205	protein histidine kinase activity
MWH18_17520	COG1024	Enoyl-CoA hydratase
MWH18_17525	COG2084	Dehydrogenase
MWH18_17530	COG3622	Belongs to the hyi family
MWH18_17560	COG0697	spore germination
MWH18_17570	COG2814	Major facilitator Superfamily
MWH18_17675	COG0740	serine-type endopeptidase activity
MWH18_17680	COG4695	Portal protein
MWH18_17685	COG4626	Terminase
MWH18_17685	COG1802	Transcriptional regulator
MWH18_17775	COG0305	Participates in initiation and elongation during chromosome replication
MWH18_17840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MWH18_17850	COG0583	DNA-binding transcription factor activity
MWH18_17860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MWH18_17875	COG0084	hydrolase, TatD family'
MWH18_17890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MWH18_17905	COG1674	ftsk spoiiie
MWH18_17925	COG4372	Transposase
MWH18_17955	COG2233	PERMEase
MWH18_18155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MWH18_18160	COG0440	acetolactate synthase activity
MWH18_18165	COG0028	Belongs to the TPP enzyme family
MWH18_18185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MWH18_18190	COG0577	efflux transmembrane transporter activity
MWH18_18190	COG1136	(ABC) transporter
MWH18_18210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MWH18_18215	COG1162	GTPase activity
MWH18_18225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MWH18_18245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MWH18_18265	COG1426	Protein conserved in bacteria
MWH18_18300	COG0793	Belongs to the peptidase S41A family
MWH18_18315	COG2267	carboxylic ester hydrolase activity
MWH18_18325	COG1012	belongs to the aldehyde dehydrogenase family
MWH18_18330	COG3265	gluconokinase activity
MWH18_18340	COG0800	Aldolase
MWH18_18355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MWH18_18360	COG0280	phosphate acetyltransferase
MWH18_18360	COG0857	belongs to the CobB CobQ family
MWH18_18365	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MWH18_18365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MWH18_18385	COG0740	serine-type endopeptidase activity
MWH18_18395	COG4774	siderophore transport
MWH18_18405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MWH18_18415	COG2813	Specifically methylates the guanine in position
MWH18_18415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MWH18_18515	COG0788	formyltetrahydrofolate deformylase activity
MWH18_18540	COG4651	solute:proton antiporter activity
MWH18_18540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MWH18_18560	COG0724	RNA recognition motif
MWH18_18565	COG0210	DNA helicase
MWH18_18590	COG1733	regulation of RNA biosynthetic process
MWH18_18595	COG0604	alcohol dehydrogenase
MWH18_18600	COG2900	Belongs to the SlyX family
MWH18_18605	COG0488	(ABC) transporter
MWH18_18615	COG1560	Kdo2-lipid A biosynthetic process
MWH18_18625	COG1301	dicarboxylic acid transport
MWH18_18680	COG0473	3-isopropylmalate dehydrogenase activity
MWH18_18705	COG0583	DNA-binding transcription factor activity
MWH18_18745	COG0583	DNA-binding transcription factor activity
MWH18_18755	COG0625	glutathione transferase activity
MWH18_18760	COG2378	regulation of single-species biofilm formation
MWH18_18765	COG0546	phosphoglycolate phosphatase activity
MWH18_18775	COG1530	ribonuclease E activity
MWH18_18780	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_18795	COG0583	DNA-binding transcription factor activity
MWH18_18800	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_18805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MWH18_18815	COG0534	Mate efflux family protein
MWH18_18830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MWH18_18855	COG0493	'glutamate synthase
MWH18_18865	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MWH18_18870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MWH18_18885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MWH18_18895	COG0644	oxidoreductase
MWH18_18895	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MWH18_18910	COG4535	Mg2 and Co2 transporter CorC
MWH18_18955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MWH18_18965	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MWH18_18975	COG0484	heat shock protein binding
MWH18_18980	COG0789	Transcriptional regulator
MWH18_18985	COG0598	Magnesium transport protein CorA
MWH18_18990	COG1185	polyribonucleotide nucleotidyltransferase activity
MWH18_19000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MWH18_19005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MWH18_19010	COG1074	ATP-dependent DNA helicase activity
MWH18_19015	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MWH18_19035	COG2226	methyltransferase
MWH18_19050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MWH18_19060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MWH18_19075	COG2111	Na H antiporter
MWH18_19075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MWH18_19080	COG1006	Multisubunit Na H antiporter MnhC subunit
MWH18_19085	COG0651	ATP synthesis coupled electron transport
MWH18_19090	COG1863	multisubunit Na H antiporter MnhE subunit
MWH18_19095	COG2212	antiporter activity
MWH18_19100	COG1320	monovalent cation:proton antiporter activity
MWH18_19105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MWH18_19115	COG0195	Participates in both transcription termination and antitermination
MWH18_19165	COG0237	dephospho-CoA kinase activity
MWH18_19175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MWH18_19190	COG0497	DNA recombination
MWH18_19200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MWH18_19235	COG2169	Transcriptional regulator
MWH18_19235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MWH18_19245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MWH18_19320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MWH18_19335	COG0326	Molecular chaperone. Has ATPase activity
MWH18_19355	COG2056	Na+-H+ antiporter family
MWH18_19425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MWH18_19455	COG0546	phosphoglycolate phosphatase activity
MWH18_19460	COG1716	ATPase activity
MWH18_19505	COG0181	hydroxymethylbilane synthase activity
MWH18_19515	COG3275	phosphorelay sensor kinase activity
MWH18_19535	COG1538	Outer membrane efflux protein
MWH18_19545	COG0697	spore germination
MWH18_19565	COG0494	nUDIX hydrolase
MWH18_19570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MWH18_19575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MWH18_19580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MWH18_19585	COG0772	Belongs to the SEDS family
MWH18_19610	COG4974	Belongs to the 'phage' integrase family
MWH18_19615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MWH18_19625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MWH18_19635	COG2197	response regulator
MWH18_19650	COG0793	Belongs to the peptidase S41A family
MWH18_19655	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MWH18_19660	COG0795	lipopolysaccharide-transporting ATPase activity
MWH18_19700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MWH18_19700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MWH18_19710	COG0004	ammonium transporteR
MWH18_19715	COG0347	Belongs to the P(II) protein family
MWH18_19725	COG0606	chelatase, subunit chli
MWH18_19730	COG0431	NADPH-dependent FMN reductase
MWH18_19735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MWH18_19740	COG0235	Class ii aldolase
MWH18_19745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MWH18_19765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MWH18_19780	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_19790	COG0477	Major facilitator Superfamily
MWH18_19795	COG2860	membrane
MWH18_19805	COG1253	flavin adenine dinucleotide binding
MWH18_19815	COG2814	Major facilitator Superfamily
MWH18_19825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MWH18_19865	COG0655	NAD(P)H dehydrogenase (quinone) activity
MWH18_19880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MWH18_19945	COG0758	DNA mediated transformation
MWH18_19955	COG0697	spore germination
MWH18_19960	COG1309	transcriptional regulator
MWH18_19975	COG0386	Belongs to the glutathione peroxidase family
MWH18_19990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MWH18_20000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MWH18_20040	COG1121	(ABC) transporter
MWH18_20045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MWH18_20050	COG1280	lysine exporter protein (LysE YggA)
MWH18_20055	COG2837	iron assimilation
MWH18_20060	COG0281	malic enzyme
MWH18_20100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MWH18_20100	COG0519	Catalyzes the synthesis of GMP from XMP
MWH18_20105	COG4399	Belongs to the UPF0754 family
MWH18_20110	COG2259	Doxx family
MWH18_20115	COG0586	Pfam SNARE associated Golgi protein
MWH18_20130	COG1192	Involved in chromosome partitioning
MWH18_20140	COG0271	Belongs to the BolA IbaG family
MWH18_20180	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MWH18_20180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MWH18_20180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MWH18_20180	COG3321	synthase
MWH18_20185	COG1960	acyl-CoA dehydrogenase activity
MWH18_20190	COG0318	PFAM AMP-dependent synthetase and ligase
MWH18_20210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MWH18_20215	COG1113	amino acid transport
MWH18_20220	COG0697	spore germination
MWH18_20225	COG0477	Major facilitator Superfamily
MWH18_20230	COG1024	Enoyl-CoA hydratase
MWH18_20235	COG1024	Enoyl-CoA hydratase
MWH18_20240	COG1960	acyl-CoA dehydrogenase activity
MWH18_20245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MWH18_20265	COG1113	amino acid transport
MWH18_20270	COG1113	amino acid transport
MWH18_20275	COG0251	oxidation-reduction process
MWH18_20315	COG0564	pseudouridine synthase activity
MWH18_20390	COG1051	belongs to the nudix hydrolase family
MWH18_20415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MWH18_20430	COG1802	Transcriptional regulator
MWH18_20440	COG1448	Aminotransferase
MWH18_20445	COG0277	FAD linked oxidase domain protein
MWH18_20455	COG2186	Transcriptional regulator
MWH18_20465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MWH18_20480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MWH18_20485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MWH18_20520	COG1091	dTDP-4-dehydrorhamnose reductase activity
MWH18_20530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MWH18_20550	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MWH18_20580	COG0728	peptidoglycan biosynthetic process
MWH18_20585	COG3023	N-Acetylmuramoyl-L-alanine amidase
MWH18_20640	COG0546	phosphoglycolate phosphatase activity
MWH18_20645	COG1028	Short-chain dehydrogenase reductase Sdr
MWH18_20670	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MWH18_20670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MWH18_20675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MWH18_20680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MWH18_20685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MWH18_20690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MWH18_20695	COG1116	anion transmembrane transporter activity
MWH18_20700	COG1309	transcriptional regulator
MWH18_20705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MWH18_20715	COG0196	riboflavin kinase activity
MWH18_20720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MWH18_20730	COG1047	Peptidyl-prolyl cis-trans
MWH18_20770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MWH18_20775	COG0657	acetylesterase activity
MWH18_20795	COG0583	DNA-binding transcription factor activity
MWH18_20825	COG2951	lytic endotransglycosylase activity
MWH18_20830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MWH18_20845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MWH18_20855	COG0671	phosphoesterase, PA-phosphatase related
MWH18_20860	COG0861	Integral membrane protein TerC family
MWH18_20870	COG0754	glutathionylspermidine amidase activity
MWH18_20880	COG0402	S-adenosylhomocysteine deaminase activity
MWH18_20895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MWH18_20900	COG1230	cation diffusion facilitator family transporter
MWH18_20915	COG0706	membrane insertase activity
MWH18_21045	COG4372	Transposase
MWH18_21100	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
MWH18_21140	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
MWH18_21150	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MWH18_21155	COG3657	addiction module killer protein
MWH18_21185	COG3328	transposase activity
MWH18_21195	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MWH18_21200	COG0604	alcohol dehydrogenase
MWH18_21200	COG3321	synthase
MWH18_21210	COG0697	spore germination
MWH18_21215	COG0477	Major facilitator Superfamily
MWH18_21245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MWH18_21260	COG1979	alcohol dehydrogenase
MWH18_21280	COG1309	transcriptional regulator
MWH18_21285	COG2130	NADP-dependent
MWH18_21300	COG0582	viral genome integration into host DNA
MWH18_21335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MWH18_21445	COG0789	Transcriptional regulator
MWH18_21555	COG3077	Addiction module antitoxin, RelB DinJ family
MWH18_21565	COG0456	acetyltransferase
MWH18_21590	COG3173	Aminoglycoside phosphotransferase
MWH18_21595	COG0488	(ABC) transporter