locus-tag class description BVD86_00055 ENOG4105KCK Peptidoglycan-associated lipoprotein BVD86_00060 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) BVD86_00070 ENOG4105M8F Biopolymer transport protein exbD tolR BVD86_00075 ENOG4105E02 MotA TolQ exbB proton channel BVD86_00080 ENOG4107YD3 Thioesterase BVD86_00085 ENOG4105CH2 amidohydrolase BVD86_00105 ENOG4108ETH Formylglycinamide ribotide synthetase BVD86_00110 ENOG4105C2C drug resistance transporter, Bcr CflA BVD86_00115 ENOG4105EGD dinuclear metal center protein, YbgI family BVD86_00120 ENOG4108UKI Enoyl-CoA hydratase BVD86_00140 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BVD86_00155 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BVD86_00160 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BVD86_00175 ENOG4107R11 Transcriptional regulator BVD86_00180 ENOG4108IJ6 ABC transporter BVD86_00190 ENOG4108I5D sulfate abc transporter BVD86_00200 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BVD86_00205 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BVD86_00210 ENOG4105HHA aminodeoxychorismate lyase BVD86_00225 ENOG4108IYU L-aspartate oxidase BVD86_00230 ENOG4105C0H protease BVD86_00240 ENOG41068WN BVD86_00245 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BVD86_00250 ENOG4105C3F Signal peptidase i BVD86_00260 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BVD86_00265 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BVD86_00275 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) BVD86_00280 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BVD86_00285 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase BVD86_00290 ENOG4105EMU Dehydrogenase BVD86_00330 ENOG4105BZU Histidine kinase BVD86_00340 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BVD86_00350 ENOG4105DTR rard protein BVD86_00385 ENOG4107QS8 (LipO)protein BVD86_00390 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BVD86_00395 ENOG4105EA8 2-Nitropropane dioxygenase BVD86_00420 ENOG4107R8N Glycosyl transferase, family 2 BVD86_00435 ENOG4105CVP deoxyribo-dipyrimidine photolyase BVD86_00440 ENOG4108YZY peptidylprolyl cis-trans isomerase BVD86_00445 ENOG4105CEP NADH dehydrogenase BVD86_00450 ENOG4105DZ1 carboxypeptidase BVD86_00460 ENOG4105E9K Isocitrate dehydrogenase BVD86_00465 ENOG4108R99 pseudouridine synthase BVD86_00480 ENOG4105CBP Major Facilitator BVD86_00485 ENOG4105EGI Transcriptional regulator BVD86_00490 ENOG4108ETY sodium dicarboxylate symporter BVD86_00495 ENOG4105JAB phenazine biosynthesis protein, phzf family BVD86_00525 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BVD86_00540 ENOG4105D3G Pseudouridine synthase BVD86_00545 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) BVD86_00560 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BVD86_00575 ENOG4108JPW Aminotransferase BVD86_00580 ENOG4105DY8 decarboxylase BVD86_00590 ENOG4105F7P transcriptional regulator AsnC family BVD86_00595 ENOG4107RA9 decarboxylase BVD86_00600 ENOG4105C85 amino acid BVD86_00605 ENOG4105CVA phosphate BVD86_00610 ENOG4105C8U phosphate abc transporter BVD86_00620 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BVD86_00625 ENOG4105ERU peptidase BVD86_00640 ENOG4107QTF adenylosuccinate lyase BVD86_00660 ENOG4108Z0R Transferase BVD86_00665 ENOG4105DZ1 carboxypeptidase BVD86_00685 ENOG4108K5P (LipO)protein BVD86_00690 ENOG4105EJC lysr family transcriptional regulator BVD86_00695 ENOG4105DAN ATP-dependent protease BVD86_00710 ENOG4105DHU Bile acid BVD86_00730 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BVD86_00735 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BVD86_00740 ENOG4105D22 carbon starvation protein BVD86_00745 ENOG4105VCD cytoplasmic protein BVD86_00755 ENOG4105DFP Integrase BVD86_00785 ENOG4105K4U addiction module toxin, RelE StbE family BVD86_00880 ENOG4105WWK YheO domain protein BVD86_00890 ENOG4105C2I pirin domain protein BVD86_00905 ENOG4105CEY Amp-dependent synthetase and ligase BVD86_00920 ENOG4108IPW abc transporter atp-binding protein BVD86_00940 ENOG4105C0W non-ribosomal peptide synthetase BVD86_00945 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BVD86_00950 ENOG4105WQI isochorismatase BVD86_00965 ENOG4105BZ1 (ABC) transporter BVD86_00985 ENOG4105E4F Isochorismate synthase BVD86_01005 ENOG4105NX3 Membrane BVD86_01020 ENOG41066YJ Beta-lactamase BVD86_01025 ENOG4105EUJ GTP cyclohydrolase i BVD86_01035 ENOG4105C7W Xanthine dehydrogenase BVD86_01045 ENOG4108DG9 Smr protein MutS2 BVD86_01060 ENOG4105DDQ anthranilate synthase BVD86_01070 ENOG4105DUX Transporter BVD86_01075 ENOG4105C5F glutamine synthetase BVD86_01085 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) BVD86_01120 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BVD86_01125 ENOG4107QNR UPF0135 protein BVD86_01130 ENOG4105C0H protease BVD86_01140 ENOG4105C6K Malic enzyme BVD86_01145 ENOG4105BZU Histidine kinase BVD86_01150 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BVD86_01155 ENOG4105SYT Methylenetetrahydrofolate reductase BVD86_01160 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) BVD86_01175 ENOG4107QPN acyl-Coa dehydrogenase BVD86_01180 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BVD86_01185 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BVD86_01195 ENOG4107RNU major facilitator superfamily MFS_1 BVD86_01205 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BVD86_01210 ENOG4105CE9 30S ribosomal protein S2 BVD86_01250 ENOG4105CVE Lytic murein transglycosylase BVD86_01255 ENOG4105CNI cell division protein FtsW BVD86_01270 ENOG4105E3A (ABC) transporter BVD86_01275 ENOG4105DA5 (ABC) transporter BVD86_01310 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BVD86_01320 ENOG4105ENT Efflux transporter rnd family, mfp subunit BVD86_01330 ENOG4105E89 ABC transporter BVD86_01335 ENOG4105DSP amino acid AbC transporter BVD86_01340 ENOG4106YG3 ABC transporter BVD86_01345 ENOG4108JEH abc transporter atp-binding protein BVD86_01355 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BVD86_01360 ENOG4105CFP Peptidase U32 BVD86_01365 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVD86_01370 ENOG4105JAB phenazine biosynthesis protein, phzf family BVD86_01375 ENOG4105DP0 ferredoxin-NADP reductase BVD86_01380 ENOG4108R96 Methyltransferase, YaeB family BVD86_01390 ENOG4107QHF type ii secretion system protein e BVD86_01400 ENOG4105XJC Two component transcriptional regulator (Winged helix family BVD86_01405 ENOG4105DHQ Histidine kinase BVD86_01415 ENOG4105M6F mutator MutT protein BVD86_01425 ENOG4105BZ4 penicillin-binding protein BVD86_01430 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BVD86_01435 ENOG4105VUT cytoplasmic protein BVD86_01440 ENOG4108I0Q anthranilate phosphoribosyltransferase BVD86_01450 ENOG4105CK2 sodium dicarboxylate symporter BVD86_01455 ENOG4105C1G acyl-Coa dehydrogenase BVD86_01465 ENOG4105CQC Prephenate dehydratase BVD86_01470 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BVD86_01480 ENOG4105CIN aminoacyl-histidine dipeptidase BVD86_01485 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BVD86_01515 ENOG4105M08 Membrane BVD86_01520 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVD86_01530 ENOG4105VEQ Cold shock protein BVD86_01535 ENOG4105C1J atp-dependent rna helicase BVD86_01545 ENOG41069NU Nitroreductase BVD86_01580 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BVD86_01595 ENOG4105C5I Dehydrogenase BVD86_01600 ENOG4105ERG peptidase m48, ste24p BVD86_01605 ENOG4105KTH gatB Yqey BVD86_01610 ENOG4105VCC 30S ribosomal protein S21 BVD86_01635 ENOG4105D9P serine threonine protein kinase BVD86_01660 ENOG4105VEQ Cold shock protein BVD86_01680 ENOG4105D6U Sodium Glutamate Symporter BVD86_01685 ENOG4105CKD glutathione-regulated potassium-efflux system protein BVD86_01705 ENOG4105CEB Aspartate aminotransferase BVD86_01720 ENOG4105F1S paraquat-inducible protein a BVD86_01725 ENOG4105DY2 Paraquat-inducible protein b BVD86_01735 ENOG4105VT2 5-hydroxyisourate hydrolase BVD86_01775 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BVD86_01785 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BVD86_01790 ENOG4105DHQ Histidine kinase BVD86_01795 ENOG4105ETX regulatoR BVD86_01815 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BVD86_01820 ENOG4105E2B Taurine dioxygenase BVD86_01830 ENOG4105F27 Major Facilitator BVD86_01845 ENOG4105HMI Membrane BVD86_01890 ENOG4105CK2 sodium dicarboxylate symporter BVD86_01900 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BVD86_01905 ENOG4108UMI ABC transporter, permease BVD86_01910 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BVD86_01915 ENOG4105D01 (LipO)protein BVD86_01920 ENOG4105C12 Phosphoribosylglycinamide synthetase BVD86_01930 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BVD86_01980 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BVD86_01985 ENOG4105CDU Replicative dna helicase BVD86_02010 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BVD86_02015 ENOG4105CCU oxidase (Subunit III) BVD86_02020 ENOG4105BZ9 Cytochrome C oxidase, subunit I BVD86_02025 ENOG4105E2S oxidase) subunit II BVD86_02050 ENOG4107BJW polysaccharide deacetylase BVD86_02055 ENOG4105CND Glycosyl transferase, family 2 BVD86_02060 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BVD86_02070 ENOG4105DEN Luciferase family BVD86_02085 ENOG4105CC0 LysR family Transcriptional regulator BVD86_02100 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BVD86_02105 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BVD86_02110 ENOG4105GVF (ABC) transporter BVD86_02125 ENOG4105C1G acyl-Coa dehydrogenase BVD86_02130 ENOG4108MEJ flavin reductase domain protein BVD86_02135 ENOG4105D06 uba thif-type nad fad binding protein BVD86_02145 ENOG4105KRF dihydroneopterin aldolase BVD86_02155 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) BVD86_02160 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) BVD86_02170 ENOG4105C08 Histidine kinase BVD86_02175 ENOG4105EEX Two component transcriptional regulator (Winged helix family BVD86_02180 ENOG4105CFQ glutamine synthetase BVD86_02195 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) BVD86_02200 ENOG4105CFU surface antigen BVD86_02225 ENOG4107QIJ Aconitate hydratase 2 BVD86_02235 ENOG4105EYW Ion transport protein BVD86_02240 ENOG4105F27 Major Facilitator BVD86_02250 ENOG4105DZ2 Transcriptional regulator BVD86_02265 ENOG4105I08 Pseudouridine synthase BVD86_02285 ENOG4105K8N protein family UPF0079, ATPase BVD86_02290 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BVD86_02300 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BVD86_02305 ENOG4108TZV Membrane BVD86_02310 ENOG4108RCM Nitroreductase BVD86_02330 ENOG4105CX6 glutaminyL-tRNA synthetase BVD86_02340 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BVD86_02345 ENOG4107FQ9 ethanolamine ammonia-lyase BVD86_02350 ENOG4105CPD ethanolamine ammonia-lyase BVD86_02355 ENOG4107R55 ethanolamine transporter BVD86_02365 ENOG4107RR1 TRANSCRIPTIONal BVD86_02375 ENOG4105C0A alcohol dehydrogenase BVD86_02380 ENOG4107QUV Domain protein BVD86_02405 ENOG4105CD8 aminopeptidase N BVD86_02425 ENOG4108D1K outer membrane usher protein BVD86_02450 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BVD86_02470 ENOG41089BK Glutamine amido-transferase BVD86_02505 ENOG4105KUS lysozyme BVD86_02515 ENOG4105KVH Transcriptional regulator BVD86_02570 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium BVD86_02575 ENOG4105C5H ABC transporter BVD86_02580 ENOG41081QV Universal stress protein BVD86_02600 ENOG4105DKK Benzoate BVD86_02605 ENOG4105EW9 transcriptional regulator AsnC family BVD86_02610 ENOG4108NIW Leucine export protein LeuE BVD86_02615 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BVD86_02620 ENOG4105CC0 LysR family Transcriptional regulator BVD86_02630 ENOG4105CHU acetyl-coa acetyltransferase BVD86_02635 ENOG4105CHR reductase BVD86_02670 ENOG4107QMP dna polymerase iii subunits gamma and tau BVD86_02675 ENOG4105HSS phospholipase C BVD86_02685 ENOG4105C0A alcohol dehydrogenase BVD86_02740 ENOG4105CBC glutamate synthase BVD86_02755 ENOG4108D1K outer membrane usher protein BVD86_03095 ENOG4105D8G Major Facilitator superfamily BVD86_03105 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BVD86_03110 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BVD86_03135 ENOG4105DUU IucA IucC family protein BVD86_03145 ENOG4105DJU Siderophore biosynthesis protein BVD86_03150 ENOG4105CIF Ornithine Cyclodeaminase BVD86_03180 ENOG4107QZF nitrite reductase NADPH large subunit BVD86_03185 ENOG4108IFG nitrite reductase, (NAD(P)H) BVD86_03220 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BVD86_03225 ENOG4105CVM Molybdenum cofactor synthesis domain protein BVD86_03235 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVD86_03240 ENOG4105T38 integral membrane protein BVD86_03265 ENOG4105CMR udp-glucose 4-epimerase BVD86_03330 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BVD86_03335 ENOG4105CUX Signal transduction histidine kinase BVD86_03360 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BVD86_03365 ENOG4105KNE Phosphatidate cytidylyltransferase BVD86_03375 ENOG4105DZP Membrane-associated zinc metalloprotease BVD86_03380 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BVD86_03400 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BVD86_03415 ENOG4105Y3E Modulates RecA activity (By similarity) BVD86_03425 ENOG4105VEJ Heat shock protein BVD86_03430 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BVD86_03445 ENOG4105F7P transcriptional regulator AsnC family BVD86_03455 ENOG4105C85 amino acid BVD86_03475 ENOG4105CHH sulfate transporter BVD86_03485 ENOG4105D8V Glucose sorbosone dehydrogenase BVD86_03495 ENOG4105BZU Histidine kinase BVD86_03515 ENOG4105DM4 PTS System BVD86_03520 ENOG4105DE4 1-phosphofructokinase BVD86_03525 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BVD86_03545 ENOG4108ZJF Glcg protein BVD86_03550 ENOG4105CWM branched-chain amino acid transport system II carrier protein BVD86_03555 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BVD86_03560 ENOG4105CC0 LysR family Transcriptional regulator BVD86_03570 ENOG4105M2J Glutaredoxin BVD86_03575 ENOG4105C8Y Acetylornithine aminotransferase BVD86_03580 ENOG4105C2X Arabinose 5-phosphate isomerase BVD86_03605 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BVD86_03635 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BVD86_03640 ENOG4105C4M (Ubiquinol oxidase) subunit I BVD86_03650 ENOG4105PV3 Inner membrane protein yqiJ BVD86_03665 ENOG4105E0K tonB-dependent siderophore receptor BVD86_03675 ENOG4105HDD phospholipase BVD86_03680 ENOG4105CZN Potassium uptake protein BVD86_03690 ENOG4105C7B Threonine dehydratase BVD86_03720 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) BVD86_03725 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BVD86_03735 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BVD86_03750 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BVD86_03790 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BVD86_03795 ENOG4107VMU Membrane BVD86_03805 ENOG4105CNM Receptor BVD86_03810 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BVD86_03820 ENOG4107QP7 CoA-transferase subunit A BVD86_03825 ENOG4107QNJ CoA-transferase subunit B BVD86_03830 ENOG4105CHU acetyl-coa acetyltransferase BVD86_03835 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase BVD86_03840 ENOG4105F2Z 3-oxoadipate enol-lactonase BVD86_03845 ENOG4105D2S major facilitator superfamily BVD86_03850 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BVD86_03855 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta BVD86_03860 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha BVD86_03865 ENOG4105FF2 Type I DHQase BVD86_03870 ENOG4106JPM 3-dehydroshikimate dehydratase BVD86_03875 ENOG4105TW1 Carbohydrate-selective porin OprB BVD86_03880 ENOG4105DZG Dehydrogenase BVD86_03890 ENOG4105MD1 YeeE YedE family protein BVD86_03905 ENOG4107HP6 Transcriptional regulator BVD86_03910 ENOG4108PTX LysR family Transcriptional regulator BVD86_03915 ENOG4105C1G acyl-Coa dehydrogenase BVD86_03940 ENOG4105DNH Major Facilitator BVD86_03950 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BVD86_03970 ENOG4105FUY alpha subunit BVD86_03980 ENOG4105CHR reductase BVD86_04000 ENOG4105F11 amine oxidase BVD86_04015 ENOG4105C26 Dehydrogenase BVD86_04020 ENOG4105F2Z 3-oxoadipate enol-lactonase BVD86_04025 ENOG4105CHU acetyl-coa acetyltransferase BVD86_04030 ENOG4107QNJ CoA-transferase subunit B BVD86_04035 ENOG4107QP7 CoA-transferase subunit A BVD86_04045 ENOG4105NN7 muconolactone delta-isomerase BVD86_04050 ENOG4105DTQ mandelate racemase muconate lactonizing BVD86_04055 ENOG4108KB2 LysR family Transcriptional regulator BVD86_04070 ENOG4107RGH Aldehyde dehydrogenase BVD86_04085 ENOG4105CH6 catalase BVD86_04105 ENOG4108R0M Aminoglycoside BVD86_04120 ENOG4105C1G acyl-Coa dehydrogenase BVD86_04125 ENOG4105CHR reductase BVD86_04130 ENOG4108JU7 Transcriptional regulator BVD86_04155 ENOG4105K56 Transcriptional regulator BVD86_04160 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BVD86_04200 ENOG4107Z3H Transcriptional regulator, TetR family BVD86_04205 ENOG4108PTX LysR family Transcriptional regulator BVD86_04210 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BVD86_04215 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BVD86_04220 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr BVD86_04230 ENOG4105CSU acyl-Coa dehydrogenase BVD86_04240 ENOG4105CEY Amp-dependent synthetase and ligase BVD86_04255 ENOG4105J7D transcriptional regulator BVD86_04265 ENOG4105DXN mazG family BVD86_04300 ENOG4106KR7 LysR family Transcriptional regulator BVD86_04325 ENOG4108JQ1 Dehydrogenase BVD86_04330 ENOG4105JSC dimethylmenaquinone methyltransferase BVD86_04350 ENOG4105EVZ LysR family transcriptional regulator BVD86_04355 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BVD86_04360 ENOG4105C26 Dehydrogenase BVD86_04385 ENOG4105CZJ Aldehyde dehydrogenase BVD86_04390 ENOG4105C01 Dihydroxy-acid dehydratase BVD86_04410 ENOG4105EXW epimerase dehydratase BVD86_04420 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BVD86_04425 ENOG4105CF7 AraC family transcriptional regulator BVD86_04430 ENOG4105DQ4 alcohol dehydrogenase BVD86_04445 ENOG4105EHG Permease protein BVD86_04450 ENOG4105E0A ABC, transporter BVD86_04470 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BVD86_04540 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) BVD86_04580 ENOG4105F8V Hydrolase, tatD family BVD86_04595 ENOG4105ENX hydrolase BVD86_04600 ENOG4105EQ2 LysR family Transcriptional regulator BVD86_04620 ENOG4108R6W Transcriptional regulator, ARAC family BVD86_04625 ENOG4108821 RND type efflux pump BVD86_04635 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BVD86_04650 ENOG4105CXG d-lactate dehydrogenase BVD86_04715 ENOG4105E2B Taurine dioxygenase BVD86_04720 ENOG4105IJJ transcriptional regulator, crp fnr family BVD86_04725 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) BVD86_04735 ENOG4105CPC Aldo Keto reductase BVD86_04740 ENOG4105CPU Monooxygenase BVD86_04755 ENOG4105E2B Taurine dioxygenase BVD86_04765 ENOG4105SG9 biopolymer transport protein, ExbD BVD86_04775 ENOG4105WQ5 TonB family BVD86_04780 ENOG4105D7T ABC transporter BVD86_04785 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BVD86_04790 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BVD86_04810 ENOG4105SG9 biopolymer transport protein, ExbD BVD86_04820 ENOG4105WQ5 TonB family BVD86_04825 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BVD86_04830 ENOG4105GVF (ABC) transporter BVD86_04840 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BVD86_04855 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) BVD86_04860 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BVD86_04865 ENOG4108JU7 Transcriptional regulator BVD86_04880 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BVD86_04890 ENOG4105BZ1 (ABC) transporter BVD86_04895 ENOG4105BZ1 (ABC) transporter BVD86_04915 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BVD86_04950 ENOG4105X0I Fimbrial BVD86_05005 ENOG4107RZC phospholipase d BVD86_05015 ENOG4105E0F Histidine kinase BVD86_05020 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVD86_05025 ENOG4105C1P efflux transporter, rnd family, mfp subunit BVD86_05030 ENOG4105BZS acriflavin resistance protein BVD86_05045 ENOG4108IGT Dipeptidase BVD86_05050 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E BVD86_05060 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) BVD86_05065 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) BVD86_05075 ENOG4107T31 5'-nucleotidase BVD86_05085 ENOG4105WQI isochorismatase BVD86_05090 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BVD86_05095 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BVD86_05100 ENOG4105E0C molybdate abc transporter BVD86_05105 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BVD86_05110 ENOG4105F4R Transcriptional regulator mode BVD86_05115 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit BVD86_05120 ENOG4108YS2 small subunit BVD86_05125 ENOG4105F57 Anthranilate dioxygenase reductase BVD86_05150 ENOG4105CHR reductase BVD86_05165 ENOG4105D2S major facilitator superfamily BVD86_05170 ENOG4105CF7 AraC family transcriptional regulator BVD86_05175 ENOG4105DTD Dehydrogenase BVD86_05180 ENOG4105CY2 Citrate transporter BVD86_05205 ENOG4108M0I Transcriptional regulator BVD86_05220 ENOG4105CRW Short chain fatty acid transporter BVD86_05225 ENOG4105CHU acetyl-coa acetyltransferase BVD86_05235 ENOG4107YNJ LysR family Transcriptional regulator BVD86_05250 ENOG4108IJ0 Aspartate ammonia-lyase BVD86_05260 ENOG4105CSH Transporter BVD86_05280 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BVD86_05285 ENOG4106FTQ Taurine ABC transporter, periplasmic BVD86_05300 ENOG4105FDP GntR family transcriptional regulator BVD86_05310 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BVD86_05315 ENOG4105KVH Transcriptional regulator BVD86_05320 ENOG4105UEI Transcriptional Regulator AraC Family BVD86_05335 ENOG4108VCT Sulfite exporter TauE/SafE BVD86_05355 ENOG4105FFC UPF0187 protein BVD86_05365 ENOG4105CHR reductase BVD86_05380 ENOG4105CPP Dehydrogenase, E1 component BVD86_05385 ENOG4107R0V Pyruvate dehydrogenase BVD86_05390 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BVD86_05405 ENOG4105BZU Histidine kinase BVD86_05420 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BVD86_05425 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BVD86_05470 ENOG4107U5X Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BVD86_05480 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BVD86_05495 ENOG4105C28 cystathionine BVD86_05515 ENOG4105K59 histidine triad (HIT) protein BVD86_05540 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BVD86_05545 ENOG4105CNM Receptor BVD86_05570 ENOG4107TSN permease BVD86_05575 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BVD86_05595 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) BVD86_05600 ENOG4108YZT Adenosylcobinamide kinase BVD86_05620 ENOG4108Z66 YbaK ebsC protein BVD86_05635 ENOG4105C1G acyl-Coa dehydrogenase BVD86_05640 ENOG4105C1G acyl-Coa dehydrogenase BVD86_05645 ENOG4105EEF Alkane 1-monooxygenase BVD86_05650 ENOG4105E7U AraC family transcriptional regulator BVD86_05655 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BVD86_05660 ENOG4105K70 DNA-binding protein BVD86_05675 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family BVD86_05685 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BVD86_05690 ENOG4108Z4V iron-sulfur cluster assembly BVD86_05705 ENOG4108ZIT Ferredoxin, 2FE-2S BVD86_05710 ENOG4105F8J Adenylate Guanylate cyclase BVD86_05720 ENOG4108JA2 transcriptioN-repair coupling factor BVD86_05740 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) BVD86_05745 ENOG4105K4T epimerase BVD86_05760 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BVD86_05795 ENOG4107QSI ABC, transporter BVD86_05825 ENOG4105SG9 biopolymer transport protein, ExbD BVD86_05835 ENOG4107QP3 malate synthase g BVD86_05840 ENOG4105D6Z AFG1 family ATPase BVD86_05850 ENOG4107RN6 Monooxygenase BVD86_05855 ENOG4105DWU Membrane BVD86_05870 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BVD86_05875 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BVD86_05890 ENOG4108Z6B deaminase BVD86_05910 ENOG4108RTD type II secretion system protein K BVD86_05935 ENOG4105F8V Hydrolase, tatD family BVD86_05945 ENOG4107QRG dna polymerase iii BVD86_05955 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) BVD86_05960 ENOG4105BZ1 (ABC) transporter BVD86_05975 ENOG4105FA0 parb-like partition protein BVD86_05980 ENOG4107QJE Chromosome Partitioning Protein BVD86_05990 ENOG4108S0S Nucleotidyl transferase BVD86_05995 ENOG4105EHM Aminoglycoside phosphotransferase BVD86_06000 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) BVD86_06005 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BVD86_06010 ENOG4105D2N Aldolase BVD86_06030 ENOG4108UHJ MAF-like protein BVD86_06035 ENOG4105EZE Cupin 4 family protein BVD86_06045 ENOG41080HT Transcriptional regulator, arsr family BVD86_06055 ENOG4105XPP Protein of unknown function (DUF1275) BVD86_06060 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BVD86_06070 ENOG4105BZ1 (ABC) transporter BVD86_06080 ENOG4108ZX5 transcriptional regulator BVD86_06090 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BVD86_06095 ENOG4105CK7 Sodium proline symporter BVD86_06100 ENOG4105EW9 transcriptional regulator AsnC family BVD86_06105 ENOG4105C26 Dehydrogenase BVD86_06110 ENOG4105YGK Pfam:UPF0157 BVD86_06125 ENOG4108T58 Mg2 transport protein CorA BVD86_06135 ENOG4108YYC ycei family BVD86_06145 ENOG4105CV1 Transketolase (EC 2.2.1.1) BVD86_06170 ENOG4108HWY Beta-lactamase BVD86_06190 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BVD86_06195 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BVD86_06215 ENOG4105X0I Fimbrial BVD86_06240 ENOG4108R4R Iron-regulated virulence regulatory protein BVD86_06245 ENOG4108IPJ Membrane BVD86_06255 ENOG4105ETS cytosine purines uracil thiamine allantoin BVD86_06265 ENOG4105CC0 LysR family Transcriptional regulator BVD86_06280 ENOG41067SE Tetr family transcriptional regulator BVD86_06295 ENOG4105EW9 transcriptional regulator AsnC family BVD86_06305 ENOG4105CDA abc transporter atp-binding protein BVD86_06310 ENOG4105DRP amino acid AbC transporter BVD86_06315 ENOG4105EAD ABC transporter BVD86_06330 ENOG4107T8P acyl-Coa dehydrogenase BVD86_06345 ENOG4105D01 (LipO)protein BVD86_06350 ENOG4105D01 (LipO)protein BVD86_06355 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BVD86_06360 ENOG4108UMI ABC transporter, permease BVD86_06365 ENOG4105C3G gtp-binding protein BVD86_06390 ENOG4108UMN azlc family BVD86_06395 ENOG4105ZED uncharacterized protein ygaH BVD86_06425 ENOG4106AXJ AraC family transcriptional regulator BVD86_06430 ENOG4108V06 Glutathione peroxidase BVD86_06440 ENOG4105CHM Aminotransferase BVD86_06445 ENOG4105CK2 sodium dicarboxylate symporter BVD86_06455 ENOG4105C0B DNA polymerase III (alpha subunit) BVD86_06480 ENOG4108JU3 Alkyl hydroperoxide reductase BVD86_06495 ENOG4108KB2 LysR family Transcriptional regulator BVD86_06500 ENOG4105D6J arsenicaL-resistance protein BVD86_06505 ENOG41082YX Transcriptional regulator, arsr family BVD86_06520 ENOG4105CPN adenine deaminase BVD86_06530 ENOG4105CBN LysR family transcriptional regulator BVD86_06540 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BVD86_06550 ENOG4105E2B Taurine dioxygenase BVD86_06555 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BVD86_06560 ENOG4108IY8 ABC, transporter BVD86_06565 ENOG4106FTQ Taurine ABC transporter, periplasmic BVD86_06575 ENOG4105C54 Major Facilitator superfamily BVD86_06600 ENOG4105C4M (Ubiquinol oxidase) subunit I BVD86_06605 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BVD86_06615 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVD86_06620 ENOG4108K70 Transcriptional regulator BVD86_06635 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BVD86_06640 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase BVD86_06655 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) BVD86_06660 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase BVD86_06670 ENOG4105DXI Major Facilitator superfamily BVD86_06690 ENOG41067MG lrgb family BVD86_06695 ENOG4105VAW lrga family BVD86_06700 ENOG4105CMU LysR family (Transcriptional regulator BVD86_06705 ENOG4108SHQ Glutathione S-transferase BVD86_06710 ENOG4105CYM Glutathione S-transferase BVD86_06730 ENOG4105CBN LysR family transcriptional regulator BVD86_06735 ENOG4105CHR reductase BVD86_06745 ENOG4105D7W serine acetyltransferase BVD86_06750 ENOG4105ESN nucleotide-binding protein BVD86_06755 ENOG4105C9B Cysteine desulfurase BVD86_06770 ENOG4105EXG Transcriptional regulator BVD86_06780 ENOG4105CT1 (ABC) transporter BVD86_06785 ENOG4107RP9 extracellular solute-binding protein, family 3 BVD86_06795 ENOG4108HW4 amino acid AbC transporter BVD86_06800 ENOG4105EAD ABC transporter BVD86_06815 ENOG4107RTG Major Facilitator superfamily BVD86_06820 ENOG4105EQ2 LysR family Transcriptional regulator BVD86_06830 ENOG4105ENX hydrolase BVD86_06835 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BVD86_06840 ENOG4105BZU Histidine kinase BVD86_06850 ENOG4105EW9 transcriptional regulator AsnC family BVD86_06860 ENOG4105KT5 UmuD protein BVD86_06880 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BVD86_06930 ENOG4105HEI LysR family (Transcriptional regulator BVD86_06945 ENOG4105D2S major facilitator superfamily BVD86_06960 ENOG4105CEY Amp-dependent synthetase and ligase BVD86_06965 ENOG4105R8C Transcriptional regulator BVD86_06970 ENOG4105C1G acyl-Coa dehydrogenase BVD86_06975 ENOG4107QX3 carboxylase BVD86_06980 ENOG4105E39 Enoyl-CoA hydratase BVD86_06995 ENOG4105CC0 LysR family Transcriptional regulator BVD86_07010 ENOG4105CSU acyl-Coa dehydrogenase BVD86_07020 ENOG4105EQ0 Major Facilitator superfamily BVD86_07030 ENOG4107QNJ CoA-transferase subunit B BVD86_07035 ENOG4107QP7 CoA-transferase subunit A BVD86_07040 ENOG4107RGD Major Facilitator superfamily BVD86_07045 ENOG4105C1G acyl-Coa dehydrogenase BVD86_07050 ENOG4105E39 Enoyl-CoA hydratase BVD86_07065 ENOG4105CHU acetyl-coa acetyltransferase BVD86_07075 ENOG4105EQ0 Major Facilitator superfamily BVD86_07080 ENOG4105EA8 2-Nitropropane dioxygenase BVD86_07085 ENOG4108UKI Enoyl-CoA hydratase BVD86_07100 ENOG4105C1G acyl-Coa dehydrogenase BVD86_07105 ENOG4107RGD Major Facilitator superfamily BVD86_07110 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BVD86_07115 ENOG4107STF Involved in phosphonate degradation (By similarity) BVD86_07125 ENOG4107RCV ABC transporter, permease BVD86_07130 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BVD86_07135 ENOG4105C4Y ABC transporter BVD86_07150 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase BVD86_07155 ENOG4107HP6 Transcriptional regulator BVD86_07165 ENOG4105HEI LysR family (Transcriptional regulator BVD86_07170 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BVD86_07175 ENOG4105C26 Dehydrogenase BVD86_07185 ENOG4105ETS cytosine purines uracil thiamine allantoin BVD86_07195 ENOG4105C26 Dehydrogenase BVD86_07200 ENOG4108M8W Monooxygenase BVD86_07235 ENOG4105CSP Major Facilitator Superfamily BVD86_07240 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BVD86_07245 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BVD86_07290 ENOG4107YAU phenylacetic acid degradation protein BVD86_07300 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein BVD86_07305 ENOG4105DZS Phenylacetate-CoA ligase BVD86_07310 ENOG4105CHU acetyl-coa acetyltransferase BVD86_07315 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BVD86_07320 ENOG4108UKI Enoyl-CoA hydratase BVD86_07325 ENOG4105E39 Enoyl-CoA hydratase BVD86_07330 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BVD86_07335 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit BVD86_07340 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit BVD86_07345 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit BVD86_07350 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit BVD86_07355 ENOG4105DXM phenylacetic acid degradation protein BVD86_07360 ENOG4105EJQ L-serine dehydratase BVD86_07365 ENOG4107QTZ amino acid BVD86_07370 ENOG4105CZJ Aldehyde dehydrogenase BVD86_07395 ENOG4105MWK D-amino acid dehydrogenase, small subunit BVD86_07415 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BVD86_07430 ENOG4108Z4X TRANSCRIPTIONal BVD86_07440 ENOG4105WPN DNA integration recombination invertion protein BVD86_07445 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVD86_07460 ENOG4105DJ2 Major Facilitator Superfamily BVD86_07465 ENOG4107Y2X deaminase BVD86_07475 ENOG4105EMY transcriptional regulator BVD86_07505 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BVD86_07515 ENOG4105EIY sodium-type flagellar protein motY BVD86_07570 ENOG4105E6M Sulphatase-modifying factor protein BVD86_07600 ENOG4105CNA YD repeat protein BVD86_07610 ENOG4105JQN Transcriptional regulator BVD86_07615 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVD86_07645 ENOG4105MRR Transcriptional regulator (By similarity) BVD86_07660 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF BVD86_07665 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BVD86_07680 ENOG4105E2A Dehydrogenase BVD86_07685 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) BVD86_07720 ENOG4107R4J Chloride channel BVD86_07725 ENOG4108JIK carboxylase BVD86_07745 ENOG4105C5A transporter BVD86_07750 ENOG4108WAV Transcriptional regulator BVD86_07760 ENOG4108WQI RNA Polymerase BVD86_07770 ENOG4105E18 UPF0276 protein BVD86_07835 ENOG4108IND Tetr family transcriptional regulator BVD86_07855 ENOG4105BZU Histidine kinase BVD86_07880 ENOG4105D2S major facilitator superfamily BVD86_07885 ENOG4105CPW cytochrome b561 BVD86_07890 ENOG4107VGR Catalase BVD86_07895 ENOG4105KVH Transcriptional regulator BVD86_07920 ENOG4105VEQ Cold shock protein BVD86_07960 ENOG4105D5Q Arginine ornithine antiporter BVD86_07965 ENOG4105CRN Aminoglycoside phosphotransferase BVD86_07975 ENOG4108ZX5 transcriptional regulator BVD86_07995 ENOG4108Z4U Ferredoxin BVD86_08025 ENOG4105C42 Type I secretion membrane fusion protein (HlyD BVD86_08035 ENOG4105DFG type I secretion outer membrane protein BVD86_08040 ENOG4108IUZ ABC transporter BVD86_08045 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BVD86_08055 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BVD86_08060 ENOG4105C2X Arabinose 5-phosphate isomerase BVD86_08100 ENOG4107YPT transcriptional regulator BVD86_08115 ENOG4105CUY Mechanosensitive ion channel BVD86_08160 ENOG4105R8C Transcriptional regulator BVD86_08190 ENOG4105F2W methyltransferase BVD86_08195 ENOG4105PAD Hydrolase BVD86_08200 ENOG4105EW9 transcriptional regulator AsnC family BVD86_08210 ENOG4105II7 pyrroline-5-carboxylate reductase BVD86_08220 ENOG4105VEQ Cold shock protein BVD86_08225 ENOG4105D1S lipid A biosynthesis BVD86_08230 ENOG410829K Lysine exporter protein (Lyse ygga) BVD86_08270 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BVD86_08340 ENOG4105EUV Phenol 2-monooxygenase BVD86_08360 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein BVD86_08370 ENOG4108KB2 LysR family Transcriptional regulator BVD86_08380 ENOG4105FUY alpha subunit BVD86_08390 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein BVD86_08395 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase BVD86_08400 ENOG4105DKK Benzoate BVD86_08405 ENOG4105D2S major facilitator superfamily BVD86_08420 ENOG4105CQ7 ATP-dependent helicase BVD86_08425 ENOG4105D3R alkyl hydroperoxide reductase BVD86_08445 ENOG4108JU3 Alkyl hydroperoxide reductase BVD86_08455 ENOG4108K3A Glutathione S-transferase BVD86_08465 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BVD86_08475 ENOG4108TGY Glutathione S-transferase BVD86_08485 ENOG4108ZG0 Ompa motb domain protein BVD86_08490 ENOG4105CD3 dihydroorotase BVD86_08520 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BVD86_08535 ENOG4108UKZ OsmC family BVD86_08545 ENOG4107RYR Transcriptional regulator, Crp Fnr family BVD86_08550 ENOG4105CPC Aldo Keto reductase BVD86_08565 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BVD86_08575 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BVD86_08585 ENOG4105CFH Aspartokinase BVD86_08595 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BVD86_08605 ENOG4105CPW cytochrome b561 BVD86_08610 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) BVD86_08615 ENOG4105C7N Xanthine uracil vitamin C permease BVD86_08645 ENOG4105F95 Monooxygenase BVD86_08650 ENOG4105JQZ Methyltransferase BVD86_08655 ENOG4105EJC lysr family transcriptional regulator BVD86_08665 ENOG4106DSS Tartrate dehydratase subunit alpha BVD86_08670 ENOG4107GFK fumarate BVD86_08680 ENOG4107RN6 Monooxygenase BVD86_08700 ENOG4105DDY UPF0142 protein ycaO BVD86_08705 ENOG4105EPF Outer membrane porin BVD86_08710 ENOG4105D2S major facilitator superfamily BVD86_08715 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) BVD86_08720 ENOG4105E6M Sulphatase-modifying factor protein BVD86_08735 ENOG4105E3J oxidoreductase BVD86_08755 ENOG4108SC4 )-transporter BVD86_08760 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase BVD86_08775 ENOG4105C1G acyl-Coa dehydrogenase BVD86_08780 ENOG4105EPF Outer membrane porin BVD86_08785 ENOG4105NI3 Protein of unknown function (DUF3237) BVD86_08800 ENOG4105DJP Membrane BVD86_08835 ENOG4106855 Competence protein BVD86_08840 ENOG4108VAU general secretion pathway protein G BVD86_08845 ENOG4105E4G Type IV pilus BVD86_08870 ENOG4107QHF type ii secretion system protein e BVD86_08880 ENOG4108VAU general secretion pathway protein G BVD86_08895 ENOG4108ZX5 transcriptional regulator BVD86_08900 ENOG4107RGH Aldehyde dehydrogenase BVD86_08925 ENOG4105C85 amino acid BVD86_08945 ENOG4105C26 Dehydrogenase BVD86_08965 ENOG4105CUB amino acid BVD86_08975 ENOG4105C85 amino acid BVD86_09005 ENOG4105CNA YD repeat protein BVD86_09010 ENOG4105CS6 Rhs element vgr protein BVD86_09025 ENOG4108M3P Membrane BVD86_09040 ENOG4105DFP Integrase BVD86_09100 ENOG4105DQ6 Transposase BVD86_09125 ENOG4105DND Transcriptional regulator BVD86_09135 ENOG4105CE7 Amidase, hydantoinase carbamoylase family BVD86_09140 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase BVD86_09145 ENOG4105MP9 class II Aldolase BVD86_09150 ENOG4105CSH Transporter BVD86_09160 ENOG4105C26 Dehydrogenase BVD86_09170 ENOG4105C8Y Acetylornithine aminotransferase BVD86_09175 ENOG4105D82 Glutamate dehydrogenase BVD86_09180 ENOG4105C85 amino acid BVD86_09190 ENOG4105EW9 transcriptional regulator AsnC family BVD86_09215 ENOG4105K6H D-cysteine desulfhydrase BVD86_09220 ENOG4105C85 amino acid BVD86_09225 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions BVD86_09255 ENOG4105R8C Transcriptional regulator BVD86_09270 ENOG41088T4 Helicase IV BVD86_09370 ENOG4105C85 amino acid BVD86_09375 ENOG4105C26 Dehydrogenase BVD86_09390 ENOG4108K8K Transcriptional regulator BVD86_09405 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BVD86_09425 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) BVD86_09445 ENOG4108JQ5 ABC transporter BVD86_09450 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BVD86_09455 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BVD86_09460 ENOG4105E43 Extracellular solute-binding protein, family 5 BVD86_09465 ENOG4105E9H Lytic Murein transglycosylase BVD86_09465 ENOG4105E9H Lytic Murein transglycosylase BVD86_09470 ENOG4108JDX DNA polymerase iii, epsilon subunit BVD86_09480 ENOG4105E09 nadh pyrophosphatase BVD86_09490 ENOG4105W4M Transport-associated protein BVD86_09500 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BVD86_09510 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BVD86_09520 ENOG4105W1Y Transcriptional regulator BVD86_09530 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BVD86_09535 ENOG4105D0A hydroxylase BVD86_09540 ENOG4107RAQ aminopeptidase BVD86_09875 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BVD86_09890 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BVD86_09900 ENOG4105D82 Glutamate dehydrogenase BVD86_09905 ENOG4108R3D Electron transport complex BVD86_09910 ENOG4105CSM endonuclease III BVD86_09935 ENOG4105CJN penicillin-binding protein BVD86_09940 ENOG4106H78 methyltransferase BVD86_09955 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) BVD86_09965 ENOG4105CQM Urea amidohydrolase subunit alpha BVD86_09990 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BVD86_09995 ENOG4107RET Isocitrate lyase BVD86_10005 ENOG4105C37 (CBS) domain BVD86_10010 ENOG4105D4T Citrate transporter BVD86_10025 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) BVD86_10040 ENOG4108MRJ BVD86_10060 ENOG4105VCQ rubredoxin BVD86_10065 ENOG4107QZF nitrite reductase NADPH large subunit BVD86_10070 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BVD86_10075 ENOG4105C5Q Transcriptional regulator BVD86_10100 ENOG4107U91 Rhomboid family BVD86_10105 ENOG4105CV6 ABC transporter, permease BVD86_10110 ENOG4108I0Y (ABC) transporter BVD86_10115 ENOG4108UJV acyl-CoA thioesterase i BVD86_10135 ENOG4107RNH Outer membrane receptor FepA BVD86_10150 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) BVD86_10155 ENOG4105E6M Sulphatase-modifying factor protein BVD86_10175 ENOG4105CJ3 phosphate transporter BVD86_10180 ENOG4105C3R Methionine synthase BVD86_10195 ENOG4105CSP Major Facilitator Superfamily BVD86_10205 ENOG4108PZW LysR family Transcriptional regulator BVD86_10220 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BVD86_10225 ENOG4105EU0 Major facilitator Superfamily BVD86_10230 ENOG4108R6W Transcriptional regulator, ARAC family BVD86_10235 ENOG4105CSV Glutaminase BVD86_10240 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BVD86_10245 ENOG4105CSH Transporter BVD86_10260 ENOG4105C7K acetolactate synthase BVD86_10275 ENOG4105CHR reductase BVD86_10280 ENOG4108MXF Alpha Beta Hydrolase BVD86_10290 ENOG4105DJB Major Facilitator Superfamily BVD86_10305 ENOG4105CHR reductase BVD86_10325 ENOG41069M3 Transcriptional regulator BVD86_10340 ENOG4105E9F Enoyl-CoA hydratase BVD86_10350 ENOG4105CND Glycosyl transferase, family 2 BVD86_10355 ENOG4107BJW polysaccharide deacetylase BVD86_10365 ENOG4108VWS Yaeq family BVD86_10395 ENOG4105C94 Transporter BVD86_10400 ENOG4105C94 Transporter BVD86_10405 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) BVD86_10430 ENOG4107QK5 Homocysteine s-methyltransferase BVD86_10435 ENOG4105D5Q Arginine ornithine antiporter BVD86_10460 ENOG4108YNN Heme oxygenase BVD86_10490 ENOG4108SF5 RNA Polymerase BVD86_10500 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BVD86_10505 ENOG4105C54 Major Facilitator superfamily BVD86_10550 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BVD86_10555 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVD86_10560 ENOG4105CW7 secretion protein, HlyD family BVD86_10565 ENOG4108VUY thioesterase Superfamily protein BVD86_10570 ENOG4105D52 delta-aminolevulinic acid dehydratase BVD86_10575 ENOG4105MWK D-amino acid dehydrogenase, small subunit BVD86_10580 ENOG4105ECP epimerase BVD86_10600 ENOG4107RH8 nuclease SbcCD subunit D BVD86_10605 ENOG4105EYH Exonuclease BVD86_10610 ENOG4105DFA alanine racemase domain protein BVD86_10615 ENOG4105CZX twitching motility protein BVD86_10620 ENOG4105CZX twitching motility protein BVD86_10625 ENOG41090R7 Ferric uptake BVD86_10635 ENOG4105VDB UPF0125 protein BVD86_10655 ENOG4105E7A Glutamine amidotransferase BVD86_10670 ENOG4107QKV phosphomannomutase BVD86_10680 ENOG4105C4R Atp-dependent dna helicase BVD86_10685 ENOG4108ZG0 Ompa motb domain protein BVD86_10690 ENOG4106HNH Acyl-transferase BVD86_10705 ENOG4107QMS site-determining protein BVD86_10725 ENOG4105CNU cell division protein FtsK BVD86_10730 ENOG4105C3M thioredoxin reductase BVD86_10735 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) BVD86_10745 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BVD86_10760 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BVD86_10765 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BVD86_10775 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BVD86_10790 ENOG4108YXA Membrane BVD86_10800 ENOG4105C4K Nad synthetase BVD86_10815 ENOG4105E3J oxidoreductase BVD86_10820 ENOG4105C26 Dehydrogenase BVD86_10825 ENOG4105DVW rieske (2Fe-2S) BVD86_10835 ENOG4105C94 Transporter BVD86_10840 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BVD86_10845 ENOG4105EJC lysr family transcriptional regulator BVD86_10865 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BVD86_10890 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BVD86_10895 ENOG4105C34 Pseudouridine synthase BVD86_10900 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BVD86_10905 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BVD86_10925 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) BVD86_10955 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BVD86_10985 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BVD86_10995 ENOG4105DWF phosphomethylpyrimidine kinase BVD86_11000 ENOG4109066 lysm domain bon superfamily protein BVD86_11010 ENOG4105CHR reductase BVD86_11015 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BVD86_11025 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BVD86_11030 ENOG4108BPE -transporting atpase BVD86_11035 ENOG4107RTD sua5 ycio yrdc ywlc family protein BVD86_11040 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) BVD86_11045 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) BVD86_11050 ENOG4105FE9 pseudouridine synthase BVD86_11070 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BVD86_11075 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BVD86_11085 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BVD86_11095 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase BVD86_11100 ENOG4106UW1 Major Facilitator superfamily BVD86_11120 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BVD86_11130 ENOG4105HF0 Membrane BVD86_11145 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BVD86_11155 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BVD86_11205 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BVD86_11210 ENOG4105D1F ATP-binding protein BVD86_11220 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BVD86_11255 ENOG4105K6H D-cysteine desulfhydrase BVD86_11260 ENOG4105CBX hi0933 family BVD86_11285 ENOG4105DP0 ferredoxin-NADP reductase BVD86_11290 ENOG4105DUM transcriptional regulator, lysR family BVD86_11310 ENOG4105C8S subunit m BVD86_11315 ENOG4105D65 subunit l BVD86_11325 ENOG4107UFS subunit j BVD86_11340 ENOG4108IEH NADH dehydrogenase subunit g BVD86_11345 ENOG4107QIZ NADH dehydrogenase BVD86_11350 ENOG4105GKE subunit e BVD86_11370 ENOG4105BZU Histidine kinase BVD86_11380 ENOG4105E0F Histidine kinase BVD86_11385 ENOG4107EXC regulatoR BVD86_11390 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BVD86_11400 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BVD86_11460 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) BVD86_11465 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BVD86_11475 ENOG4105ETT transcriptional Regulator, LysR family BVD86_11495 ENOG4105CH2 amidohydrolase BVD86_11530 ENOG4106P55 Transcriptional regulator BVD86_11550 ENOG4106P55 Transcriptional regulator BVD86_11555 ENOG4107EFR Flavocytochrome c BVD86_11580 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F BVD86_11585 ENOG4107RGD Major Facilitator superfamily BVD86_11590 ENOG4105C1G acyl-Coa dehydrogenase BVD86_11595 ENOG4105ETT transcriptional Regulator, LysR family BVD86_11605 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) BVD86_11630 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BVD86_11635 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BVD86_11640 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BVD86_11660 ENOG4105E3B Multicopper oxidase BVD86_11670 ENOG4108HCJ Hydrolase BVD86_11675 ENOG4105DJV ribulose-phosphate 3-epimerase BVD86_11685 ENOG4105C4W S-formylglutathione hydrolase BVD86_11700 ENOG41072GX Peptidase M22 Glycoprotease BVD86_11705 ENOG4108Z0R Transferase BVD86_11750 ENOG4105CRQ synthase (Component I) BVD86_11760 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BVD86_11765 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BVD86_11770 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BVD86_11840 ENOG4105K56 Transcriptional regulator BVD86_11845 ENOG4108ZHJ Organic hydroperoxide resistance protein BVD86_11850 ENOG4107QHF type ii secretion system protein e BVD86_11870 ENOG4105C2M dna polymerase I BVD86_11875 ENOG4108VIA integral membrane protein BVD86_11880 ENOG4105II7 pyrroline-5-carboxylate reductase BVD86_11885 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BVD86_11895 ENOG4105C9X ppx gppa phosphatase BVD86_11905 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BVD86_11925 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BVD86_11950 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BVD86_11955 ENOG41082NX 50s ribosomal protein l35 BVD86_11970 ENOG4105W39 Membrane BVD86_11975 ENOG4105CYM Glutathione S-transferase BVD86_11995 ENOG4105CEY Amp-dependent synthetase and ligase BVD86_12000 ENOG4105N42 UPF0307 protein BVD86_12005 ENOG41080Z8 PHOSPHOCARRIER protein BVD86_12025 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BVD86_12030 ENOG4105DJ0 Poly(A) Polymerase BVD86_12035 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BVD86_12040 ENOG4105DXN mazG family BVD86_12045 ENOG4105EMU Dehydrogenase BVD86_12050 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BVD86_12065 ENOG4105C6T cysteine synthase BVD86_12070 ENOG4105BZU Histidine kinase BVD86_12075 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase BVD86_12080 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BVD86_12085 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BVD86_12105 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BVD86_12110 ENOG4105W8H transhydrogenase (subunit alpha BVD86_12115 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BVD86_12120 ENOG4106UX7 integral membrane protein BVD86_12135 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BVD86_12150 ENOG4107RSM transcriptional regulator BVD86_12160 ENOG4105CUZ uba thif-type nad fad binding protein BVD86_12165 ENOG4107QM5 aconitate hydratase BVD86_12170 ENOG4105F8V Hydrolase, tatD family BVD86_12185 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) BVD86_12200 ENOG4105BZU Histidine kinase BVD86_12205 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BVD86_12210 ENOG4108ZP8 Acetolactate synthase small subunit BVD86_12215 ENOG4105C7K acetolactate synthase BVD86_12235 ENOG4105DJY efflux transporter, rnd family, mfp subunit BVD86_12240 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BVD86_12245 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BVD86_12250 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH BVD86_12260 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) BVD86_12265 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BVD86_12275 ENOG4105VW4 glutaredoxin 3 BVD86_12295 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BVD86_12300 ENOG4105C2D reductase BVD86_12310 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BVD86_12340 ENOG4105C84 Histidine ammonia-lyase BVD86_12355 ENOG4105CEY Amp-dependent synthetase and ligase BVD86_12370 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BVD86_12390 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BVD86_12410 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) BVD86_12430 ENOG4105WVQ Fe-S assembly protein IscX BVD86_12445 ENOG4105CN1 protease BVD86_12460 ENOG4106HB6 Alpha beta hydrolase BVD86_12470 ENOG4105C26 Dehydrogenase BVD86_12475 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BVD86_12480 ENOG4105C6Z Gluconate BVD86_12485 ENOG4108UHU Aldolase BVD86_12490 ENOG4105C01 Dihydroxy-acid dehydratase BVD86_12500 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BVD86_12505 ENOG4108DNC Involved in acetate metabolism (By similarity) BVD86_12510 ENOG4107GFK fumarate BVD86_12530 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BVD86_12540 ENOG4108ESX Receptor BVD86_12550 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) BVD86_12560 ENOG4105DWV Homoserine O-trans-acetylase BVD86_12660 ENOG4105CIY formyltetrahydrofolate deformylase BVD86_12670 ENOG4107RGH Aldehyde dehydrogenase BVD86_12675 ENOG4105KDC 50s ribosomal protein l28 BVD86_12680 ENOG4105W0E 50S ribosomal protein L33 BVD86_12685 ENOG4105CKD glutathione-regulated potassium-efflux system protein BVD86_12705 ENOG4105VFU Rna-binding protein BVD86_12710 ENOG4105C4R Atp-dependent dna helicase BVD86_12725 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BVD86_12735 ENOG4105KVH Transcriptional regulator BVD86_12745 ENOG41069P5 Protein slyX homolog BVD86_12750 ENOG4105C5H ABC transporter BVD86_12760 ENOG4105D1S lipid A biosynthesis BVD86_12770 ENOG4105CK2 sodium dicarboxylate symporter BVD86_12825 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BVD86_12880 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BVD86_12895 ENOG4108W5M transcriptional regulator BVD86_12910 ENOG4105D29 Helix-turn-helix type 11 domain protein BVD86_12915 ENOG4107XGZ Hydrolase BVD86_12920 ENOG4105EI2 Pseudouridine synthase BVD86_12930 ENOG4105C03 ribonuclease BVD86_12950 ENOG4105CBN LysR family transcriptional regulator BVD86_12960 ENOG4105CSA Coproporphyrinogen iii oxidase BVD86_12970 ENOG4107QI1 Mate efflux family protein BVD86_12980 ENOG4107T8P acyl-Coa dehydrogenase BVD86_13015 ENOG4105BZ8 glutamate synthase BVD86_13025 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) BVD86_13030 ENOG4105C5X domain protein BVD86_13045 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BVD86_13055 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BVD86_13060 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) BVD86_13065 ENOG4108JU5 Magnesium and cobalt efflux protein BVD86_13070 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BVD86_13075 ENOG4108Z7R Chaperone CsaA BVD86_13085 ENOG4108VAU general secretion pathway protein G BVD86_13090 ENOG4105D7Q type ii secretion system BVD86_13095 ENOG4105C25 Primosomal protein n' BVD86_13105 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BVD86_13115 ENOG4105DVC DnaJ domain protein BVD86_13120 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) BVD86_13125 ENOG4107QUT magnesium and cobalt transport protein CorA BVD86_13130 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BVD86_13145 ENOG4107QYX exodeoxyribonuclease v alpha BVD86_13150 ENOG4107QKA exodeoxyribonuclease V beta BVD86_13155 ENOG4105DSY exodeoxyribonuclease V, gamma BVD86_13165 ENOG4105CSR polyphosphate kinase 2 BVD86_13175 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BVD86_13195 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase BVD86_13200 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BVD86_13215 ENOG4105D65 subunit l BVD86_13220 ENOG4108ZE9 Monovalent cation H antiporter subunit C BVD86_13225 ENOG4107R4Z monovalent cation h antiporter subunit d BVD86_13230 ENOG4105SC1 monovalent cation H antiporter subunit E BVD86_13235 ENOG4105W4C monovalent cation H antiporter subunit F BVD86_13240 ENOG4105KJM monovalent cation h antiporter subunit g BVD86_13245 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BVD86_13255 ENOG4105CHV Transcription elongation factor NusA BVD86_13280 ENOG4107EJC Preprotein translocase subunit SecG BVD86_13290 ENOG4107QHF type ii secretion system protein e BVD86_13305 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BVD86_13315 ENOG4105C2N RNA methyltransferase TrmH family group 3 BVD86_13330 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BVD86_13340 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BVD86_13375 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BVD86_13380 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BVD86_13430 ENOG4108Z6Z Transcriptional regulator BVD86_13440 ENOG4107ZXU DSBA oxidoreductase BVD86_13455 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BVD86_13470 ENOG4105D3Y Na H antiporter BVD86_13525 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BVD86_13530 ENOG4105PM1 preprotein translocase subunit SecE BVD86_13540 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BVD86_13570 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BVD86_13575 ENOG4105TV9 FHA Domain-Containing protein BVD86_13580 ENOG4105GVR general secretion pathway protein D BVD86_13595 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS BVD86_13620 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BVD86_13625 ENOG4108NEV two component transcriptional regulator, LytTR family BVD86_13630 ENOG4108HRK Histidine kinase BVD86_13645 ENOG4108UTW Plays a role in the regulation of phosphate uptake BVD86_13650 ENOG4105DFG type I secretion outer membrane protein BVD86_13660 ENOG4108RNG Permease of the drug metabolite transporter BVD86_13685 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BVD86_13690 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BVD86_13695 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BVD86_13700 ENOG4105CNI cell division protein FtsW BVD86_13715 ENOG4105CE1 Ferrous iron transport protein b BVD86_13725 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BVD86_13730 ENOG4105T95 Thiol disulfide interChange protein BVD86_13735 ENOG4105D6E homoserine dehydrogenase BVD86_13745 ENOG41061WM D-Alanyl-D-Alanine BVD86_13755 ENOG4107TUY Histidine kinase BVD86_13760 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BVD86_13765 ENOG4105CN1 protease BVD86_13770 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BVD86_13775 ENOG4108K5H permease YjgP YjgQ family protein BVD86_13815 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BVD86_13825 ENOG4105BZU Histidine kinase BVD86_13840 ENOG4105C0P Mg chelatase subunit ChlI BVD86_13845 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BVD86_13850 ENOG4105FB2 class II Aldolase BVD86_13855 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BVD86_13870 ENOG4105EPF Outer membrane porin BVD86_13875 ENOG4105F0N pyrophosphate phospho-hydrolase BVD86_13890 ENOG4105CEY Amp-dependent synthetase and ligase BVD86_13895 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BVD86_13900 ENOG41079KZ Major Facilitator Superfamily BVD86_13905 ENOG4105EN6 Membrane BVD86_13915 ENOG4105EE5 Membrane protein terC BVD86_13920 ENOG4108URH decarboxylase BVD86_13925 ENOG4105C0R drug resistance transporter emrb qaca subfamily BVD86_13935 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BVD86_13955 ENOG4105CCT upf0313 protein BVD86_13975 ENOG4105CS1 NAD(P)H quinone oxidoreductase BVD86_13990 ENOG4105C6T cysteine synthase BVD86_14055 ENOG4105C79 DNA protecting protein DprA BVD86_14070 ENOG4108IND Tetr family transcriptional regulator BVD86_14075 ENOG4107RTG Major Facilitator superfamily BVD86_14085 ENOG4108V06 Glutathione peroxidase BVD86_14100 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BVD86_14110 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BVD86_14125 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BVD86_14150 ENOG4105FDK ABC transporter BVD86_14155 ENOG4105FAV ABC, transporter BVD86_14165 ENOG4105EZR dyp-type peroxidase family protein BVD86_14170 ENOG4107R1I NAD-dependent malic enzyme BVD86_14200 ENOG4105EUB pirin domain protein BVD86_14215 ENOG4108428 Inherit from COG: -acetyltransferase BVD86_14220 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BVD86_14225 ENOG4106MP8 UPF0754 membrane protein BVD86_14230 ENOG4108VBZ doxx family BVD86_14235 ENOG4105DQR SNARE associated Golgi BVD86_14250 ENOG4107QJE Chromosome Partitioning Protein BVD86_14260 ENOG4107PSF BolA-like protein BVD86_14300 ENOG4105C0W non-ribosomal peptide synthetase BVD86_14305 ENOG4105C1G acyl-Coa dehydrogenase BVD86_14310 ENOG4107RCI amp-dependent synthetase and ligase BVD86_14330 ENOG4105CSH Transporter BVD86_14335 ENOG4105E39 Enoyl-CoA hydratase BVD86_14340 ENOG4105E39 Enoyl-CoA hydratase BVD86_14345 ENOG4105C1G acyl-Coa dehydrogenase BVD86_14355 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BVD86_14360 ENOG4105C26 Dehydrogenase BVD86_14370 ENOG4105C85 amino acid BVD86_14375 ENOG4105C85 amino acid BVD86_14380 ENOG4105M4H endoribonuclease L-psp BVD86_14395 ENOG4105EW9 transcriptional regulator AsnC family BVD86_14420 ENOG4105D3G Pseudouridine synthase BVD86_14440 ENOG4108IG5 Transcriptional regulator BVD86_14460 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BVD86_14480 ENOG4108I0Z Aconitate hydratase BVD86_14485 ENOG4105BZN citrate synthase BVD86_14490 ENOG4105CR4 methylisocitrate lyase BVD86_14495 ENOG4105DRR Transcriptional regulator, GntR family BVD86_14505 ENOG4105CGF Aromatic amino acid aminotransferase BVD86_14510 ENOG4105CXG d-lactate dehydrogenase BVD86_14520 ENOG41073TP transcriptional regulator BVD86_14525 ENOG4105DAA L-lactate BVD86_14530 ENOG4107QKV phosphomannomutase BVD86_14535 ENOG4105CMR udp-glucose 4-epimerase BVD86_14545 ENOG4105C6Y Udp-glucose 6-dehydrogenase BVD86_14550 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BVD86_14560 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family BVD86_14580 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BVD86_14615 ENOG4108IJ1 Dehydrogenase BVD86_14620 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BVD86_14625 ENOG4107QQG Dehydrogenase BVD86_14630 ENOG4105DAY polysaccharide export protein BVD86_14640 ENOG4105D75 Capsular exopolysaccharide family BVD86_14645 ENOG4108V1T peptidylprolyl cis-trans isomerase BVD86_14650 ENOG4108V1T peptidylprolyl cis-trans isomerase BVD86_14655 ENOG4105CJR Integral membrane protein (MviN BVD86_14660 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BVD86_14665 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BVD86_14675 ENOG4105HSS phospholipase C BVD86_14705 ENOG41062JF Transcriptional regulator BVD86_14720 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BVD86_14725 ENOG4105UBK short-chain dehydrogenase reductase BVD86_14740 ENOG4107QZM n-acetylglutamate synthase BVD86_14745 ENOG4105GVF (ABC) transporter BVD86_14750 ENOG4105GVF (ABC) transporter BVD86_14755 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BVD86_14760 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BVD86_14765 ENOG4108VM9 ABC, transporter BVD86_14770 ENOG4108R86 Transcriptional regulator BVD86_14775 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BVD86_14785 ENOG4105DTN riboflavin biosynthesis protein ribF BVD86_14790 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BVD86_14800 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BVD86_14840 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BVD86_14905 ENOG4105CVE Lytic murein transglycosylase BVD86_14910 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BVD86_14915 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BVD86_14925 ENOG4105DFU Cell wall formation (By similarity) BVD86_14935 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BVD86_14940 ENOG4105DU1 integral membrane protein, terc BVD86_14950 ENOG4106032 Glutathionylspermidine synthase BVD86_14960 ENOG4107QUY Guanine deaminase BVD86_14965 ENOG4108UGV hypoxanthine phosphoribosyltransferase BVD86_14975 ENOG4105T95 Thiol disulfide interChange protein BVD86_14980 ENOG4105PGM cation diffusion facilitator family transporter BVD86_14995 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BVD86_15010 ENOG4105VG0 50S ribosomal protein l34 BVD86_15020 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BVD86_15030 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BVD86_15045 ENOG4105C5H ABC transporter BVD86_15050 ENOG4108821 RND type efflux pump BVD86_15065 ENOG4108821 RND type efflux pump BVD86_15075 ENOG4105D74 hydrolase BVD86_15080 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) BVD86_15085 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BVD86_15130 ENOG4105C8J )-transporter BVD86_15140 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BVD86_15170 ENOG4105C2W permease BVD86_15180 ENOG4108IG5 Transcriptional regulator BVD86_15185 ENOG4105DJY efflux transporter, rnd family, mfp subunit BVD86_15220 ENOG4105F27 Major Facilitator BVD86_15225 ENOG4105CV8 reductase BVD86_15230 ENOG4105HEI LysR family (Transcriptional regulator BVD86_15250 ENOG4105DQ4 alcohol dehydrogenase BVD86_15255 ENOG4108R3E Dna-3-methyladenine glycosylase i BVD86_15270 ENOG4105CEN a g-specific adenine glycosylase BVD86_15290 ENOG4108ZZ3 UPF0260 protein BVD86_15295 ENOG4105D8V Glucose sorbosone dehydrogenase BVD86_15300 ENOG4105D1H recombination factor protein RarA BVD86_15305 ENOG4105S64 Formate nitrite transporter BVD86_15325 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BVD86_15330 ENOG4108RWI nicotinamidase BVD86_15335 ENOG4105C09 Bile acid BVD86_15340 ENOG4105UQX Mate efflux family protein BVD86_15345 ENOG4105EWC Purine nucleoside phosphorylase BVD86_15360 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BVD86_15365 ENOG4108RXX maleylacetoacetate isomerase BVD86_15375 ENOG4105C85 amino acid BVD86_15385 ENOG4105CKI cobalamin synthesis protein BVD86_15395 ENOG4105CZE histidine utilization repressor BVD86_15400 ENOG41090B9 response to stress BVD86_15415 ENOG4105C85 amino acid BVD86_15425 ENOG41088SP formiminoglutamate hydrolase BVD86_15435 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BVD86_15440 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BVD86_15450 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BVD86_15460 ENOG4108ZAI phosphatidylglycerophosphatase a BVD86_15465 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BVD86_15480 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BVD86_15520 ENOG4105KHC sulfurtransferase BVD86_15550 ENOG4105BZU Histidine kinase BVD86_15555 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BVD86_15570 ENOG4107QJQ Mate efflux family protein BVD86_15575 ENOG4105CHM Aminotransferase BVD86_15580 ENOG4106BRA Membrane BVD86_15595 ENOG4105D9M gamma-glutamylcysteine synthetase BVD86_15605 ENOG4105CS6 Rhs element vgr protein BVD86_15645 ENOG4105IPS esterase BVD86_15650 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BVD86_15655 ENOG4108Z2U ureidoglycolate hydrolase BVD86_15665 ENOG41061H0 Monooxygenase BVD86_15680 ENOG41084YZ Hydrolase BVD86_15710 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BVD86_15715 ENOG4105BZU Histidine kinase BVD86_15730 ENOG4105KUZ arsenate reductase BVD86_15735 ENOG4105CGK Exodeoxyribonuclease III BVD86_15765 ENOG4105D7Z glutathione synthase BVD86_15785 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BVD86_15790 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BVD86_15795 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BVD86_15810 ENOG41063SB peptidase BVD86_15815 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BVD86_15820 ENOG4107QSN dihydrolipoamide acetyltransferase BVD86_15835 ENOG4105E0K tonB-dependent siderophore receptor BVD86_15845 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BVD86_15860 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BVD86_15870 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BVD86_15880 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BVD86_15885 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BVD86_15895 ENOG4105D64 Mechanosensitive ion channel BVD86_15905 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BVD86_15910 ENOG4108W2Y isochorismatase BVD86_15920 ENOG4105FBW Monooxygenase BVD86_15925 ENOG4108UZX fmn reductase BVD86_15940 ENOG4105BZU Histidine kinase BVD86_15945 ENOG41062QD Membrane BVD86_15950 ENOG4107QN1 sodium solute BVD86_15960 ENOG4105C94 Transporter BVD86_15970 ENOG4105BZU Histidine kinase BVD86_15975 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BVD86_15980 ENOG4108WUH Transcriptional regulator, TetR family BVD86_15995 ENOG4105RA2 Membrane BVD86_16000 ENOG4105EMU Dehydrogenase BVD86_16010 ENOG4105DWF phosphomethylpyrimidine kinase BVD86_16020 ENOG4107RDB Major Facilitator BVD86_16025 ENOG4108UUM single-stranded DNA-binding protein BVD86_16035 ENOG4108UMN azlc family BVD86_16055 ENOG4108JPW Aminotransferase BVD86_16060 ENOG4105C26 Dehydrogenase BVD86_16070 ENOG4105CHJ isochorismatase hydrolase BVD86_16075 ENOG4105EUB pirin domain protein BVD86_16105 ENOG4105D94 Major Facilitator Superfamily BVD86_16110 ENOG4106NZI LysR family Transcriptional regulator BVD86_16130 ENOG4105CPC Aldo Keto reductase BVD86_16135 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) BVD86_16150 ENOG4105R8C Transcriptional regulator BVD86_16175 ENOG4105KVH Transcriptional regulator BVD86_16180 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BVD86_16200 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BVD86_16205 ENOG4108UQN AraC family transcriptional regulator BVD86_16265 ENOG4105CUV Homoserine Kinase BVD86_16280 ENOG410631K Membrane BVD86_16290 ENOG4105BZ1 (ABC) transporter BVD86_16300 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BVD86_16310 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BVD86_16340 ENOG4105CYC Transferase BVD86_16350 ENOG4105E0F Histidine kinase BVD86_16355 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BVD86_16365 ENOG4105CHH sulfate transporter BVD86_16370 ENOG4105PDP Short chain dehydrogenase BVD86_16380 ENOG4105C5H ABC transporter BVD86_16465 ENOG4108IQI permease BVD86_16490 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BVD86_16505 ENOG4105CJN penicillin-binding protein BVD86_16510 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BVD86_16515 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BVD86_16530 ENOG4105DHI Methyltransferase BVD86_16535 ENOG4108JQC penicillin-binding protein 1A BVD86_16560 ENOG4105E4G Type IV pilus BVD86_16580 ENOG4105CBC glutamate synthase BVD86_16585 ENOG4105BZ8 glutamate synthase BVD86_16595 ENOG4108V0P LemA family BVD86_16600 ENOG4105HA9 of methanol dehydrogenase type BVD86_16615 ENOG4108YSG O-Antigen polymerase BVD86_16620 ENOG4108UQY Iron-storage protein BVD86_16630 ENOG4105KME endoribonuclease L-psp BVD86_16635 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BVD86_16645 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BVD86_16695 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) BVD86_16705 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BVD86_16710 ENOG4107IFA Lipase (EC 3.1.1.3) BVD86_16715 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) BVD86_16720 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BVD86_16735 ENOG4107AQZ Membrane BVD86_16740 ENOG4107AQZ Membrane BVD86_16745 ENOG4108JQ1 Dehydrogenase BVD86_16750 ENOG4105CQB FAD linked oxidase domain protein BVD86_16760 ENOG4105VRH Antibiotic biosynthesis monooxygenase BVD86_16765 ENOG4105NF4 modulator of drug activity BVD86_16775 ENOG4107QF7 multi-drug BVD86_16780 ENOG4105EM2 membrane BVD86_16785 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BVD86_16790 ENOG4105IPI Membrane BVD86_16795 ENOG4107SKI cobyrinic Acid a,c-diamide synthase BVD86_16825 ENOG4108IQI permease BVD86_16830 ENOG4105D82 Glutamate dehydrogenase BVD86_16835 ENOG4105C8Y Acetylornithine aminotransferase BVD86_16845 ENOG4105C26 Dehydrogenase BVD86_16870 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BVD86_16900 ENOG4108MIB BVD86_16915 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BVD86_16950 ENOG41067S9 phage shock protein C, PspC BVD86_16960 ENOG4105CSU acyl-Coa dehydrogenase BVD86_16975 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) BVD86_16990 ENOG4105ECY inositol monophosphatase BVD86_16995 ENOG4105C1J atp-dependent rna helicase BVD86_17005 ENOG4105DHJ ABC, transporter BVD86_17010 ENOG4105CY3 ABC transporter, permease BVD86_17020 ENOG4105E3I toluene tolerance BVD86_17030 ENOG4105D7N magnesium and cobalt transport protein CorA BVD86_17035 ENOG4108URH decarboxylase BVD86_17045 ENOG4105MJ2 Competence protein BVD86_17050 ENOG4105CB5 ATP-dependent DNA helicase recG BVD86_17065 ENOG4105E55 glycerol-3-phosphate acyltransferase BVD86_17070 ENOG4105C29 acyl-CoA thioesterase BVD86_17075 ENOG4105CK2 sodium dicarboxylate symporter BVD86_17090 ENOG4105KPV Transcriptional regulator BVD86_17100 ENOG4105D7A ATP-binding protein BVD86_17105 ENOG4105C28 cystathionine BVD86_17110 ENOG41089BK Glutamine amido-transferase BVD86_17120 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BVD86_17125 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BVD86_17220 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BVD86_17225 ENOG41067V7 50S ribosomal protein L36 BVD86_17235 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BVD86_17260 ENOG4105C1G acyl-Coa dehydrogenase BVD86_17295 ENOG4105VKU nucleicacid-binding protein BVD86_17300 ENOG4105DGW oligopeptidase A BVD86_17305 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BVD86_17350 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BVD86_17355 ENOG4107S2Z UPF0761 membrane protein BVD86_17360 ENOG4105CS1 NAD(P)H quinone oxidoreductase BVD86_17390 ENOG4105C9A Phoh family BVD86_17400 ENOG4105E4C Lytic transglycosylase catalytic BVD86_17430 ENOG4105D6S protein involved in catabolism of external DNA BVD86_17435 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BVD86_17480 ENOG4105C1G acyl-Coa dehydrogenase BVD86_17485 ENOG4108RZE Tetr family transcriptional regulator BVD86_17500 ENOG4107QX3 carboxylase BVD86_17505 ENOG4105C1G acyl-Coa dehydrogenase BVD86_17525 ENOG4105KB2 stringent starvation protein b BVD86_17530 ENOG4107MKT Stringent starvation protein a BVD86_17535 ENOG4108UJD 30S ribosomal protein S9 BVD86_17540 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BVD86_17545 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BVD86_17550 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BVD86_17555 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BVD86_17575 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BVD86_17585 ENOG4107RZC phospholipase d BVD86_17600 ENOG4108KHX Diguanylate cyclase BVD86_17605 ENOG4108WS1 BVD86_17655 ENOG4107QPB Beta-lactamase domain protein BVD86_17660 ENOG4107U2T alpha beta BVD86_17670 ENOG4105NAU thioesterase Superfamily protein BVD86_17705 ENOG4105K9H YciI-like protein BVD86_17720 ENOG4105FFC UPF0187 protein BVD86_17730 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BVD86_17735 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BVD86_17740 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BVD86_17745 ENOG4105VIE preprotein translocase, subunit YajC BVD86_17825 ENOG4106050 phage regulatory protein, rha family BVD86_17835 ENOG4105UPP uncharacterized protein ydcA BVD86_17950 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BVD86_17995 ENOG4105ED4 portal protein BVD86_18010 ENOG4105BZU Histidine kinase BVD86_18015 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) BVD86_18020 ENOG4105CM2 brancheD-chain amino acid aminotransferase BVD86_18035 ENOG4107BJW polysaccharide deacetylase BVD86_18045 ENOG4108PQP glycosyl transferase group 1 BVD86_18085 ENOG4105UGU tonB-dependent Receptor BVD86_18110 ENOG4105CSU acyl-Coa dehydrogenase BVD86_18115 ENOG4105CSU acyl-Coa dehydrogenase BVD86_18125 ENOG4105EB3 Histidine kinase BVD86_18130 ENOG4105E3W Two component transcriptional regulator (Winged helix family BVD86_18140 ENOG4105CNG UPF0061 protein BVD86_18160 ENOG4108WBT adenosyltransferase BVD86_18165 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BVD86_18175 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BVD86_18210 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BVD86_18230 ENOG4105D3R alkyl hydroperoxide reductase BVD86_18245 ENOG4105CSH Transporter BVD86_18250 ENOG4108UT2 hemolysin iii BVD86_18260 ENOG41082BV acetyltransferase BVD86_18280 ENOG4105CHU acetyl-coa acetyltransferase BVD86_18285 ENOG4108R6W Transcriptional regulator, ARAC family BVD86_18295 ENOG4105TW1 Carbohydrate-selective porin OprB BVD86_18300 ENOG4105DZG Dehydrogenase BVD86_18305 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BVD86_18325 ENOG4105CHU acetyl-coa acetyltransferase BVD86_18330 ENOG4105X0D Fimbrial protein BVD86_18335 ENOG4108WHA ompa motb domain protein BVD86_18340 ENOG4105E0Y RtcB Protein BVD86_18345 ENOG4108IQI permease BVD86_18355 ENOG4105C2W permease BVD86_18375 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) BVD86_18380 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BVD86_18390 ENOG4108VX5 3-methyladenine DNA glycosylase BVD86_18395 ENOG4105CHB tonB-dependent Receptor BVD86_18400 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BVD86_18415 ENOG4105T95 Thiol disulfide interChange protein BVD86_18420 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) BVD86_18440 ENOG4105C2W permease BVD86_18445 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) BVD86_18450 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) BVD86_18455 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BVD86_18460 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) BVD86_18465 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) BVD86_18470 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BVD86_18475 ENOG4105K78 MarR family Transcriptional regulator BVD86_18480 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BVD86_18485 ENOG4105KWI UPF0339 protein BVD86_18510 ENOG4108UNF response regulator BVD86_18515 ENOG4105M3Z response regulator BVD86_18520 ENOG4108ZGA chew protein BVD86_18525 ENOG4105C8Q Methyl-accepting chemotaxis BVD86_18530 ENOG4105CBS Chea signal transduction histidine kinase BVD86_18545 ENOG4106HKS Entericidin EcnA/B family BVD86_18555 ENOG4105WD1 Membrane BVD86_18560 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BVD86_18600 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BVD86_18610 ENOG4105EM2 membrane BVD86_18615 ENOG4105C2C drug resistance transporter, Bcr CflA BVD86_18640 ENOG4105BZG amino acid carrier protein BVD86_18645 ENOG4105D78 K07001 NTE family protein BVD86_18650 ENOG4105C7B Threonine dehydratase BVD86_18680 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BVD86_18690 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) BVD86_18695 ENOG4105DFF Rod shape-determining protein mreb BVD86_18700 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BVD86_18705 ENOG4105VQ7 Rod shape-determining protein MreD BVD86_18710 ENOG4108Z03 MAF-like protein BVD86_18715 ENOG4105C03 ribonuclease BVD86_18725 ENOG4105D8T Acyltransferase BVD86_18735 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein BVD86_18745 ENOG4108X0B nad(p)h dehydrogenase (quinone) BVD86_18770 ENOG4105CF7 AraC family transcriptional regulator BVD86_18810 ENOG4105C85 amino acid BVD86_18815 ENOG4105C7F AcnD-accessory protein PrpF BVD86_18820 ENOG4105CTB Polyprenyl synthetase BVD86_18825 ENOG4105MSB protein, conserved in bacteria BVD86_18840 ENOG4105D78 K07001 NTE family protein BVD86_18865 ENOG4105DIJ Phosphoethanolamine transferase BVD86_18870 ENOG4105XJC Two component transcriptional regulator (Winged helix family BVD86_18875 ENOG4105DHQ Histidine kinase BVD86_18890 ENOG4108M0I Transcriptional regulator BVD86_18915 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BVD86_18935 ENOG4105K8R UPF0145 protein BVD86_18940 ENOG4105K8R UPF0145 protein BVD86_18945 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BVD86_18950 ENOG4105BZS acriflavin resistance protein BVD86_18955 ENOG4105C1P efflux transporter, rnd family, mfp subunit BVD86_18960 ENOG410841Q phosphoesterase PA-phosphatase related protein BVD86_18985 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) BVD86_19000 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BVD86_19005 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BVD86_19040 ENOG4105CUB amino acid BVD86_19055 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) BVD86_19060 ENOG41084BA UPF0250 protein BVD86_19065 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BVD86_19105 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BVD86_19110 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BVD86_19120 ENOG4105E33 succinate dehydrogenase BVD86_19135 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BVD86_19140 ENOG4105C7S Dehydrogenase BVD86_19145 ENOG4107QN2 dihydrolipoyl dehydrogenase BVD86_19155 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BVD86_19165 ENOG4105CKW Inner membrane protein yedI BVD86_19170 ENOG4105CGZ zinc metallopeptidase BVD86_19175 ENOG4105EEQ Na H antiporter BVD86_19190 ENOG4105PNM synthesis protein BVD86_19210 ENOG41080TK Universal stress protein BVD86_19220 ENOG4108UQ8 endoribonuclease L-psp BVD86_19235 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BVD86_19240 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BVD86_19265 ENOG4105HBR Rna-binding protein BVD86_19275 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BVD86_19280 ENOG4105EEI dihydropteroate synthase BVD86_19335 ENOG4105CSH Transporter BVD86_19340 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BVD86_19345 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BVD86_19360 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BVD86_19375 ENOG41080IJ Diacylglycerol kinase BVD86_19385 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BVD86_19390 ENOG4105BZS acriflavin resistance protein BVD86_19405 ENOG4105E4C Lytic transglycosylase catalytic BVD86_19430 ENOG4108RRZ Transcription elongation factor GreB BVD86_19440 ENOG4105CHR reductase BVD86_19450 ENOG410642W LysR family Transcriptional regulator BVD86_19455 ENOG4105D01 (LipO)protein BVD86_19500 ENOG4105C1P efflux transporter, rnd family, mfp subunit BVD86_19505 ENOG4105BZS acriflavin resistance protein BVD86_19525 ENOG4105BZW Glycerate kinase BVD86_19530 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit BVD86_19535 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BVD86_19550 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) BVD86_19560 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BVD86_19565 ENOG4105BZG amino acid carrier protein BVD86_19570 ENOG4105C85 amino acid BVD86_19580 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BVD86_19595 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BVD86_19600 ENOG4105N14 lysine exporter protein LysE YggA BVD86_19605 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BVD86_19610 ENOG4105BZJ Electron transfer flavoprotein BVD86_19615 ENOG4105C10 Electron transfer flavoprotein BVD86_19620 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BVD86_19635 ENOG4107KET secretion protein, HlyD family BVD86_19660 ENOG4108594 Permease of the drug metabolite transporter BVD86_19665 ENOG4105D60 lipoprotein releasing system transmembrane protein BVD86_19670 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BVD86_19675 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BVD86_19685 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) BVD86_19690 ENOG4107R6F Alpha Beta Hydrolase Fold protein BVD86_19695 ENOG4108V3E phosphoribosylglycinamide formyltransferase BVD86_19705 ENOG4105C02 permease BVD86_19760 ENOG4105XUP Phage derived protein Gp49-like (DUF891) BVD86_19765 ENOG4108HWY Beta-lactamase