locus-tag	class	description
BVD86_00040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVD86_00060	COG0823	Involved in the tonB-independent uptake of proteins
BVD86_00080	COG0824	Thioesterase
BVD86_00085	COG1473	amidohydrolase
BVD86_00105	COG0047	phosphoribosylformylglycinamidine synthase activity
BVD86_00105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVD86_00110	COG2814	Major facilitator Superfamily
BVD86_00115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVD86_00120	COG1024	Enoyl-CoA hydratase
BVD86_00125	COG1056	cytidyltransferase-related domain
BVD86_00125	COG1051	belongs to the nudix hydrolase family
BVD86_00140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVD86_00155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVD86_00170	COG4625	pathogenesis
BVD86_00175	COG0583	DNA-binding transcription factor activity
BVD86_00180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVD86_00185	COG4208	sulfate ABC transporter
BVD86_00190	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BVD86_00200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BVD86_00205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVD86_00210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVD86_00230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVD86_00240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVD86_00245	COG0481	GTPase activity
BVD86_00250	COG0681	Belongs to the peptidase S26 family
BVD86_00260	COG0571	ribonuclease III activity
BVD86_00265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVD86_00275	COG1381	Involved in DNA repair and RecF pathway recombination
BVD86_00280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BVD86_00290	COG4221	oxidoreductase activity
BVD86_00340	COG0556	nucleotide-excision repair
BVD86_00350	COG2962	Rard protein
BVD86_00395	COG2070	2-Nitropropane dioxygenase
BVD86_00420	COG1215	transferase activity, transferring glycosyl groups
BVD86_00435	COG0415	Belongs to the DNA photolyase family
BVD86_00445	COG1252	NADH dehydrogenase
BVD86_00450	COG1686	Belongs to the peptidase S11 family
BVD86_00465	COG1187	pseudouridine synthase activity
BVD86_00480	COG0477	Major facilitator Superfamily
BVD86_00485	COG0583	DNA-binding transcription factor activity
BVD86_00500	COG0612	Peptidase, M16
BVD86_00525	COG0352	thiamine-phosphate diphosphorylase activity
BVD86_00560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_00575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVD86_00580	COG0076	glutamate decarboxylase activity
BVD86_00590	COG1522	sequence-specific DNA binding
BVD86_00595	COG3961	Belongs to the TPP enzyme family
BVD86_00600	COG1113	amino acid transport
BVD86_00605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVD86_00610	COG0573	inorganic phosphate transmembrane transporter activity
BVD86_00620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVD86_00625	COG0616	signal peptide processing
BVD86_00660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVD86_00665	COG1686	Belongs to the peptidase S11 family
BVD86_00690	COG0583	DNA-binding transcription factor activity
BVD86_00695	COG1067	ATP-dependent peptidase activity
BVD86_00735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVD86_00740	COG1966	Carbon starvation protein
BVD86_00745	COG2879	small protein
BVD86_00755	COG0582	viral genome integration into host DNA
BVD86_00785	COG2026	Addiction module toxin, RelE StbE family
BVD86_00800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BVD86_00880	COG2964	Protein conserved in bacteria
BVD86_00890	COG1741	Belongs to the pirin family
BVD86_00905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_00910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVD86_00915	COG4605	iron ion homeostasis
BVD86_00920	COG4604	ABC transporter, ATP-binding protein
BVD86_00925	COG4607	ABC-type enterochelin transport system periplasmic component
BVD86_00930	COG4774	siderophore transport
BVD86_00940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_00945	COG1021	2,3-dihydroxybenzoate-AMP ligase
BVD86_00950	COG3433	isochorismatase activity
BVD86_00950	COG1535	isochorismatase
BVD86_00965	COG1132	(ABC) transporter
BVD86_00975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BVD86_00985	COG1169	isochorismate synthase
BVD86_01005	COG3739	integral membrane protein
BVD86_01025	COG0302	gtp cyclohydrolase
BVD86_01035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVD86_01045	COG2840	Smr protein MutS2
BVD86_01060	COG0512	Glutamine amidotransferase of anthranilate synthase
BVD86_01070	COG3104	oligopeptide transport
BVD86_01085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVD86_01120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVD86_01125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVD86_01130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVD86_01150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVD86_01155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVD86_01160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BVD86_01175	COG1960	acyl-CoA dehydrogenase activity
BVD86_01180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVD86_01185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_01195	COG2223	nitrite transmembrane transporter activity
BVD86_01205	COG0024	Methionine aminopeptidase
BVD86_01210	COG0052	Belongs to the universal ribosomal protein uS2 family
BVD86_01225	COG2207	Transcriptional regulator
BVD86_01250	COG2951	lytic endotransglycosylase activity
BVD86_01255	COG0772	Belongs to the SEDS family
BVD86_01270	COG0842	Transport permease protein
BVD86_01275	COG1131	(ABC) transporter
BVD86_01310	COG1538	Outer membrane efflux protein
BVD86_01320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_01330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_01335	COG4215	(ABC) transporter
BVD86_01340	COG4160	amino acid transport
BVD86_01345	COG4598	ABC transporter
BVD86_01355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVD86_01365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_01370	COG0384	phenazine biosynthesis protein PhzF
BVD86_01380	COG1720	tRNA m6t6A37 methyltransferase activity
BVD86_01400	COG0745	RESPONSE REGULATOR receiver
BVD86_01405	COG0642	Histidine kinase
BVD86_01415	COG0494	nUDIX hydrolase
BVD86_01425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVD86_01430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVD86_01435	COG3139	Protein of unknown function (DUF1315)
BVD86_01440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVD86_01450	COG1301	dicarboxylic acid transport
BVD86_01455	COG1960	acyl-CoA dehydrogenase activity
BVD86_01470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVD86_01480	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVD86_01485	COG1234	tRNA 3'-trailer cleavage
BVD86_01515	COG2363	Small membrane protein
BVD86_01535	COG0513	Belongs to the DEAD box helicase family
BVD86_01545	COG0778	Nitroreductase
BVD86_01575	COG1286	toxin biosynthetic process
BVD86_01600	COG4783	chaperone-mediated protein folding
BVD86_01605	COG1610	YqeY-like protein
BVD86_01610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVD86_01635	COG0515	serine threonine protein kinase
BVD86_01635	COG2815	serine threonine protein kinase
BVD86_01660	COG1278	Cold shock
BVD86_01675	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVD86_01680	COG0786	glutamate:sodium symporter activity
BVD86_01685	COG0475	glutathione-regulated potassium exporter activity
BVD86_01685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVD86_01710	COG2985	domain, Protein
BVD86_01720	COG2995	paraquat-inducible protein a
BVD86_01725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVD86_01725	COG3008	intermembrane lipid transfer
BVD86_01735	COG2351	hydroxyisourate hydrolase activity
BVD86_01775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVD86_01785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVD86_01790	COG0642	Histidine kinase
BVD86_01795	COG0745	RESPONSE REGULATOR receiver
BVD86_01810	COG1794	racemase activity, acting on amino acids and derivatives
BVD86_01820	COG2175	clavaminate synthase activity
BVD86_01825	COG3246	L-lysine catabolic process to acetate
BVD86_01830	COG2814	Major facilitator Superfamily
BVD86_01845	COG2855	membrane
BVD86_01890	COG1301	dicarboxylic acid transport
BVD86_01900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVD86_01905	COG2011	ABC-type metal ion transport system permease component
BVD86_01910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVD86_01920	COG0151	Belongs to the GarS family
BVD86_01930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BVD86_01960	COG2308	Evidence 4 Homologs of previously reported genes of
BVD86_01970	COG1305	Transglutaminase-like
BVD86_01980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVD86_01985	COG0305	Participates in initiation and elongation during chromosome replication
BVD86_02010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BVD86_02015	COG1845	cytochrome c oxidase, subunit III
BVD86_02020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVD86_02050	COG1649	PFAM Uncharacterised BCR, COG1649
BVD86_02050	COG0726	polysaccharide deacetylase
BVD86_02055	COG1215	transferase activity, transferring glycosyl groups
BVD86_02060	COG3658	cytochrome
BVD86_02070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_02085	COG0583	DNA-binding transcription factor activity
BVD86_02100	COG2890	protein-(glutamine-N5) methyltransferase activity
BVD86_02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_02110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_02125	COG1960	acyl-CoA dehydrogenase activity
BVD86_02130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_02145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVD86_02155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVD86_02160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVD86_02170	COG2205	protein histidine kinase activity
BVD86_02175	COG0745	RESPONSE REGULATOR receiver
BVD86_02180	COG0174	glutamine synthetase
BVD86_02195	COG0477	Major facilitator Superfamily
BVD86_02200	COG0729	surface antigen
BVD86_02235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVD86_02240	COG2814	Major facilitator Superfamily
BVD86_02250	COG0583	DNA-binding transcription factor activity
BVD86_02265	COG1187	pseudouridine synthase activity
BVD86_02285	COG0802	atpase or kinase
BVD86_02290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVD86_02300	COG1923	regulation of RNA biosynthetic process
BVD86_02305	COG0697	spore germination
BVD86_02330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVD86_02340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVD86_02340	COG0519	Catalyzes the synthesis of GMP from XMP
BVD86_02345	COG4302	ethanolamine ammonia-lyase activity
BVD86_02350	COG4303	Ethanolamine ammonia lyase large subunit
BVD86_02355	COG0531	amino acid
BVD86_02375	COG1454	alcohol dehydrogenase
BVD86_02380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVD86_02405	COG0308	aminopeptidase N
BVD86_02450	COG1605	Chorismate mutase
BVD86_02505	COG3772	lysozyme
BVD86_02515	COG1733	regulation of RNA biosynthetic process
BVD86_02540	COG0583	DNA-binding transcription factor activity
BVD86_02575	COG0488	(ABC) transporter
BVD86_02580	COG0589	response to stress
BVD86_02600	COG3135	benzoate transporter
BVD86_02605	COG1522	sequence-specific DNA binding
BVD86_02615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVD86_02620	COG0583	DNA-binding transcription factor activity
BVD86_02630	COG0183	Belongs to the thiolase family
BVD86_02670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVD86_02680	COG0824	Thioesterase
BVD86_02685	COG1454	alcohol dehydrogenase
BVD86_02710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVD86_02740	COG0069	glutamate synthase activity
BVD86_02890	COG5410	chromosome segregation
BVD86_03095	COG2814	Major facilitator Superfamily
BVD86_03110	COG0511	ligase activity, forming carbon-carbon bonds
BVD86_03135	COG4264	IucA IucC family
BVD86_03145	COG4264	IucA IucC family
BVD86_03150	COG2423	ornithine cyclodeaminase activity
BVD86_03155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVD86_03165	COG1116	anion transmembrane transporter activity
BVD86_03165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_03180	COG2146	nitrite reductase [NAD(P)H] activity
BVD86_03180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_03185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_03190	COG0243	molybdopterin cofactor binding
BVD86_03200	COG0243	molybdopterin cofactor binding
BVD86_03205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVD86_03220	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVD86_03220	COG0315	cyclic pyranopterin monophosphate synthase activity
BVD86_03225	COG0303	'Molybdopterin
BVD86_03235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_03240	COG0697	spore germination
BVD86_03265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVD86_03330	COG2204	response regulator
BVD86_03335	COG3852	Histidine kinase
BVD86_03360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVD86_03365	COG0575	Belongs to the CDS family
BVD86_03380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVD86_03400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVD86_03415	COG2137	regulation of response to DNA damage stimulus
BVD86_03425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVD86_03430	COG1011	Hydrolase
BVD86_03445	COG1522	sequence-specific DNA binding
BVD86_03455	COG1113	amino acid transport
BVD86_03475	COG0659	secondary active sulfate transmembrane transporter activity
BVD86_03495	COG3300	MHYT domain
BVD86_03495	COG5001	Diguanylate cyclase
BVD86_03515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVD86_03515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVD86_03515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BVD86_03520	COG1105	Belongs to the carbohydrate kinase PfkB family
BVD86_03525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVD86_03525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD86_03545	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BVD86_03555	COG0024	Methionine aminopeptidase
BVD86_03560	COG0583	DNA-binding transcription factor activity
BVD86_03570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVD86_03575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVD86_03580	COG0517	IMP dehydrogenase activity
BVD86_03580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVD86_03605	COG0552	protein localization to endoplasmic reticulum
BVD86_03630	COG4890	Cyd operon protein YbgT
BVD86_03635	COG1294	oxidase, subunit
BVD86_03650	COG1585	Membrane protein implicated in regulation of membrane protease activity
BVD86_03660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVD86_03665	COG4774	siderophore transport
BVD86_03680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVD86_03685	COG0569	domain protein
BVD86_03690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVD86_03720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVD86_03725	COG0542	response to heat
BVD86_03735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVD86_03750	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD86_03750	COG1902	pentaerythritol trinitrate reductase activity
BVD86_03790	COG0148	phosphopyruvate hydratase activity
BVD86_03795	COG2323	membrane
BVD86_03805	COG4773	Receptor
BVD86_03810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BVD86_03820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVD86_03825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVD86_03830	COG0183	Belongs to the thiolase family
BVD86_03835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVD86_03840	COG0596	Alpha beta hydrolase
BVD86_03845	COG2271	Major facilitator Superfamily
BVD86_03850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVD86_03855	COG3485	protocatechuate 3,4-dioxygenase
BVD86_03860	COG3485	protocatechuate 3,4-dioxygenase
BVD86_03865	COG0710	3-dehydroquinate dehydratase activity
BVD86_03870	COG3420	alginic acid biosynthetic process
BVD86_03875	COG3659	wide pore channel activity
BVD86_03880	COG4993	Dehydrogenase
BVD86_03890	COG2391	methyltransferase activity
BVD86_03905	COG1414	Transcriptional regulator
BVD86_03910	COG0583	DNA-binding transcription factor activity
BVD86_03915	COG1960	acyl-CoA dehydrogenase activity
BVD86_03940	COG2814	Major facilitator Superfamily
BVD86_03950	COG0154	amidase activity
BVD86_03970	COG4638	Rieske (2fe-2S)
BVD86_03980	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_03990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_04000	COG3733	amine oxidase
BVD86_04015	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_04020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVD86_04025	COG0183	Belongs to the thiolase family
BVD86_04030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVD86_04035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVD86_04045	COG4829	muconolactone delta-isomerase
BVD86_04050	COG4948	Mandelate Racemase Muconate Lactonizing
BVD86_04055	COG0583	DNA-binding transcription factor activity
BVD86_04070	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_04085	COG0753	catalase activity
BVD86_04105	COG3231	kanamycin kinase activity
BVD86_04120	COG1960	acyl-CoA dehydrogenase activity
BVD86_04125	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_04130	COG3829	transcription factor binding
BVD86_04155	COG1846	Transcriptional regulator
BVD86_04160	COG1902	pentaerythritol trinitrate reductase activity
BVD86_04160	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD86_04200	COG1309	transcriptional regulator
BVD86_04205	COG0583	DNA-binding transcription factor activity
BVD86_04210	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_04215	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_04220	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_04230	COG1960	acyl-CoA dehydrogenase activity
BVD86_04240	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_04255	COG1309	transcriptional regulator
BVD86_04265	COG3956	TIGRFAM MazG family protein
BVD86_04300	COG0583	DNA-binding transcription factor activity
BVD86_04325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVD86_04330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVD86_04385	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_04390	COG0129	dihydroxy-acid dehydratase activity
BVD86_04410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVD86_04420	COG2084	Dehydrogenase
BVD86_04425	COG2207	Transcriptional regulator
BVD86_04430	COG1064	alcohol dehydrogenase
BVD86_04450	COG1120	ATPase activity
BVD86_04470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVD86_04540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVD86_04580	COG0084	hydrolase, TatD family'
BVD86_04595	COG1073	alpha beta
BVD86_04620	COG2207	Transcriptional regulator
BVD86_04635	COG4628	conserved protein (DUF2132)
BVD86_04650	COG0277	FAD linked oxidase domain protein
BVD86_04670	COG2271	Major facilitator Superfamily
BVD86_04705	COG1309	transcriptional regulator
BVD86_04715	COG2175	clavaminate synthase activity
BVD86_04720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVD86_04735	COG0667	Aldo Keto reductase
BVD86_04755	COG2175	clavaminate synthase activity
BVD86_04785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_04790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_04795	COG4771	TonB-dependent receptor
BVD86_04825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_04830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_04835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_04840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_04855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVD86_04860	COG0805	protein transport
BVD86_04870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_04890	COG1132	(ABC) transporter
BVD86_04895	COG1132	(ABC) transporter
BVD86_04915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVD86_04920	COG0601	transmembrane transport
BVD86_04950	COG3539	Fimbrial protein
BVD86_04975	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BVD86_04985	COG0753	catalase activity
BVD86_05005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVD86_05015	COG2205	protein histidine kinase activity
BVD86_05020	COG0745	RESPONSE REGULATOR receiver
BVD86_05025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_05030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVD86_05085	COG1535	isochorismatase
BVD86_05085	COG3433	isochorismatase activity
BVD86_05090	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_05095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BVD86_05100	COG4149	molybdate abc transporter
BVD86_05105	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVD86_05115	COG4638	Rieske (2fe-2S)
BVD86_05120	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BVD86_05125	COG0543	2 iron, 2 sulfur cluster binding
BVD86_05125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_05140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_05150	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_05155	COG0412	Dienelactone hydrolase
BVD86_05170	COG2207	Transcriptional regulator
BVD86_05175	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_05180	COG2610	gluconate transmembrane transporter activity
BVD86_05205	COG0583	DNA-binding transcription factor activity
BVD86_05220	COG2031	fatty acid transporter
BVD86_05225	COG0183	Belongs to the thiolase family
BVD86_05230	COG0583	DNA-binding transcription factor activity
BVD86_05235	COG0583	DNA-binding transcription factor activity
BVD86_05250	COG1027	Aspartate ammonia-lyase
BVD86_05260	COG0477	Major facilitator Superfamily
BVD86_05280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_05285	COG4521	taurine ABC transporter
BVD86_05310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVD86_05315	COG1733	regulation of RNA biosynthetic process
BVD86_05320	COG2207	Transcriptional regulator
BVD86_05320	COG3708	Transcriptional regulator
BVD86_05335	COG0730	response to heat
BVD86_05355	COG3781	membrane
BVD86_05360	COG1063	alcohol dehydrogenase
BVD86_05370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_05375	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVD86_05380	COG0022	dehydrogenase e1 component
BVD86_05385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVD86_05390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVD86_05405	COG3706	GGDEF domain
BVD86_05425	COG0133	tryptophan synthase activity
BVD86_05435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVD86_05465	COG0583	DNA-binding transcription factor activity
BVD86_05470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BVD86_05480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVD86_05540	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVD86_05545	COG4773	Receptor
BVD86_05570	COG0730	response to heat
BVD86_05575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVD86_05595	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BVD86_05620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVD86_05635	COG1960	acyl-CoA dehydrogenase activity
BVD86_05640	COG1960	acyl-CoA dehydrogenase activity
BVD86_05645	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVD86_05650	COG2207	Transcriptional regulator
BVD86_05655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVD86_05660	COG0776	regulation of translation
BVD86_05685	COG0822	iron-sulfur transferase activity
BVD86_05690	COG0316	Belongs to the HesB IscA family
BVD86_05720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVD86_05740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVD86_05745	COG0702	epimerase
BVD86_05785	COG0601	transmembrane transport
BVD86_05795	COG4166	transmembrane transport
BVD86_05835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BVD86_05840	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVD86_05855	COG2431	L-lysine efflux transmembrane transporter activity
BVD86_05870	COG0776	regulation of translation
BVD86_05890	COG0590	tRNA wobble adenosine to inosine editing
BVD86_05935	COG0084	hydrolase, TatD family'
BVD86_05955	COG1663	tetraacyldisaccharide 4'-kinase activity
BVD86_05960	COG1132	(ABC) transporter
BVD86_05970	COG0811	peptide transport
BVD86_05975	COG1475	DNA binding
BVD86_05980	COG1192	Involved in chromosome partitioning
BVD86_05990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVD86_05995	COG3178	'Phosphotransferase
BVD86_06005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVD86_06030	COG0424	maF-like protein
BVD86_06035	COG2850	peptidyl-arginine hydroxylation
BVD86_06045	COG0640	Transcriptional regulator
BVD86_06055	COG3619	membrane
BVD86_06060	COG3122	Protein conserved in bacteria
BVD86_06070	COG1132	(ABC) transporter
BVD86_06090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVD86_06095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVD86_06105	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVD86_06105	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BVD86_06105	COG0506	proline dehydrogenase activity
BVD86_06110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BVD86_06125	COG3698	Phosphodiester glycosidase
BVD86_06135	COG2353	YceI-like domain
BVD86_06145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVD86_06190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVD86_06190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVD86_06215	COG3539	Fimbrial protein
BVD86_06240	COG0583	DNA-binding transcription factor activity
BVD86_06245	COG0697	spore germination
BVD86_06255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVD86_06265	COG0583	DNA-binding transcription factor activity
BVD86_06280	COG1309	transcriptional regulator
BVD86_06295	COG1522	sequence-specific DNA binding
BVD86_06305	COG1126	abc transporter atp-binding protein
BVD86_06310	COG0765	amino acid transport
BVD86_06315	COG0765	amino acid transport
BVD86_06345	COG1464	Belongs to the NlpA lipoprotein family
BVD86_06355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVD86_06360	COG2011	ABC-type metal ion transport system permease component
BVD86_06365	COG0012	GTP binding
BVD86_06390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BVD86_06425	COG2207	Transcriptional regulator
BVD86_06425	COG1917	Cupin 2, conserved barrel domain protein
BVD86_06430	COG0386	Belongs to the glutathione peroxidase family
BVD86_06440	COG0436	Aminotransferase
BVD86_06445	COG1301	dicarboxylic acid transport
BVD86_06480	COG3634	alkyl hydroperoxide reductase activity
BVD86_06495	COG0583	DNA-binding transcription factor activity
BVD86_06500	COG0798	PFAM Bile acid sodium symporter
BVD86_06505	COG0640	Transcriptional regulator
BVD86_06520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BVD86_06530	COG0583	DNA-binding transcription factor activity
BVD86_06540	COG1953	Uracil, thiamine, allantoin
BVD86_06550	COG2175	clavaminate synthase activity
BVD86_06555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_06560	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BVD86_06565	COG4521	taurine ABC transporter
BVD86_06575	COG0477	Major facilitator Superfamily
BVD86_06600	COG1271	oxidase subunit
BVD86_06605	COG1294	oxidase, subunit
BVD86_06615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_06635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVD86_06655	COG3052	prosthetic group binding
BVD86_06660	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BVD86_06670	COG2814	Major facilitator Superfamily
BVD86_06690	COG1346	cytolysis
BVD86_06700	COG0583	DNA-binding transcription factor activity
BVD86_06705	COG0625	glutathione transferase activity
BVD86_06710	COG0625	glutathione transferase activity
BVD86_06730	COG0583	DNA-binding transcription factor activity
BVD86_06745	COG1045	serine acetyltransferase
BVD86_06750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVD86_06755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVD86_06765	COG1280	lysine exporter protein (LysE YggA)
BVD86_06780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_06785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_06795	COG0765	amino acid transport
BVD86_06800	COG0765	amino acid transport
BVD86_06840	COG2205	protein histidine kinase activity
BVD86_06840	COG0784	Response regulator, receiver
BVD86_06860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BVD86_06880	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_06930	COG0583	DNA-binding transcription factor activity
BVD86_06945	COG2814	Major facilitator Superfamily
BVD86_06960	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_06965	COG1309	transcriptional regulator
BVD86_06970	COG1960	acyl-CoA dehydrogenase activity
BVD86_06975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVD86_06980	COG1024	Enoyl-CoA hydratase
BVD86_06995	COG0583	DNA-binding transcription factor activity
BVD86_07010	COG1960	acyl-CoA dehydrogenase activity
BVD86_07020	COG2814	Major facilitator Superfamily
BVD86_07030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVD86_07035	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BVD86_07040	COG2814	Major facilitator Superfamily
BVD86_07045	COG1960	acyl-CoA dehydrogenase activity
BVD86_07050	COG1024	Enoyl-CoA hydratase
BVD86_07065	COG0183	Belongs to the thiolase family
BVD86_07075	COG2814	Major facilitator Superfamily
BVD86_07085	COG1024	Enoyl-CoA hydratase
BVD86_07100	COG1960	acyl-CoA dehydrogenase activity
BVD86_07105	COG2814	Major facilitator Superfamily
BVD86_07110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVD86_07115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVD86_07130	COG3842	ATPase activity
BVD86_07135	COG1840	ABC-type Fe3 transport system, periplasmic component
BVD86_07150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_07155	COG1414	Transcriptional regulator
BVD86_07165	COG0583	DNA-binding transcription factor activity
BVD86_07170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVD86_07175	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_07185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BVD86_07195	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_07200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_07235	COG2271	Major facilitator Superfamily
BVD86_07240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVD86_07245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVD86_07290	COG2050	protein possibly involved in aromatic compounds catabolism
BVD86_07300	COG3327	negative regulation of DNA-templated transcription, initiation
BVD86_07305	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BVD86_07310	COG0183	Belongs to the thiolase family
BVD86_07315	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVD86_07320	COG1024	Enoyl-CoA hydratase
BVD86_07325	COG1024	Enoyl-CoA hydratase
BVD86_07330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_07335	COG2151	metal-sulfur cluster biosynthetic enzyme
BVD86_07340	COG3396	Phenylacetate-CoA oxygenase
BVD86_07345	COG3460	Phenylacetate-CoA oxygenase
BVD86_07350	COG3396	Phenylacetate-CoA oxygenase
BVD86_07355	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_07355	COG2030	dehydratase
BVD86_07360	COG1760	l-serine dehydratase
BVD86_07365	COG0531	amino acid
BVD86_07370	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_07395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVD86_07415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_07430	COG0789	Transcriptional regulator
BVD86_07440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVD86_07445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_07460	COG2807	transmembrane transport
BVD86_07465	COG0590	tRNA wobble adenosine to inosine editing
BVD86_07475	COG0583	DNA-binding transcription factor activity
BVD86_07515	COG2885	chlorophyll binding
BVD86_07570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVD86_07600	COG4104	PAAR repeat-containing protein
BVD86_07600	COG3209	COG3209 Rhs family protein
BVD86_07615	COG0477	Major facilitator Superfamily
BVD86_07630	COG1116	anion transmembrane transporter activity
BVD86_07645	COG0864	Transcriptional regulator
BVD86_07655	COG1733	regulation of RNA biosynthetic process
BVD86_07660	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_07665	COG0439	Biotin carboxylase
BVD86_07680	COG1063	alcohol dehydrogenase
BVD86_07685	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVD86_07720	COG0038	chloride channel
BVD86_07725	COG4770	biotin carboxylase activity
BVD86_07745	COG1914	H( )-stimulated, divalent metal cation uptake system
BVD86_07750	COG0583	DNA-binding transcription factor activity
BVD86_07760	COG1595	DNA-templated transcription, initiation
BVD86_07770	COG3220	belongs to the UPF0276 family
BVD86_07835	COG1309	transcriptional regulator
BVD86_07885	COG3038	cytochrome b561
BVD86_07890	COG0753	catalase activity
BVD86_07895	COG1733	regulation of RNA biosynthetic process
BVD86_07920	COG1278	Cold shock
BVD86_07955	COG1522	sequence-specific DNA binding
BVD86_07960	COG0531	amino acid
BVD86_07965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVD86_07980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVD86_07995	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BVD86_08035	COG1538	Outer membrane efflux protein
BVD86_08040	COG1137	ATPase activity
BVD86_08045	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVD86_08055	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BVD86_08100	COG1733	regulation of RNA biosynthetic process
BVD86_08105	COG2814	Major facilitator Superfamily
BVD86_08115	COG0668	transmembrane transport
BVD86_08160	COG1309	transcriptional regulator
BVD86_08190	COG2226	methyltransferase
BVD86_08195	COG1011	Hydrolase
BVD86_08220	COG1278	Cold shock
BVD86_08225	COG1560	Kdo2-lipid A biosynthetic process
BVD86_08230	COG1280	lysine exporter protein (LysE YggA)
BVD86_08270	COG1570	exodeoxyribonuclease VII activity
BVD86_08360	COG2871	sodium ion transport
BVD86_08370	COG0583	DNA-binding transcription factor activity
BVD86_08380	COG4638	Rieske (2fe-2S)
BVD86_08390	COG0543	2 iron, 2 sulfur cluster binding
BVD86_08390	COG0633	Ferredoxin
BVD86_08395	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_08400	COG3135	benzoate transporter
BVD86_08405	COG2814	Major facilitator Superfamily
BVD86_08420	COG1643	Atp-dependent helicase
BVD86_08425	COG0450	alkyl hydroperoxide reductase
BVD86_08445	COG3634	alkyl hydroperoxide reductase activity
BVD86_08465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVD86_08475	COG0625	glutathione transferase activity
BVD86_08485	COG2885	chlorophyll binding
BVD86_08520	COG0542	response to heat
BVD86_08535	COG1765	OsmC-like protein
BVD86_08550	COG0667	Aldo Keto reductase
BVD86_08565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVD86_08595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVD86_08605	COG3038	cytochrome b561
BVD86_08610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BVD86_08615	COG2252	PERMEase
BVD86_08625	COG1741	Belongs to the pirin family
BVD86_08630	COG1309	transcriptional regulator
BVD86_08645	COG2072	flavoprotein involved in K transport
BVD86_08650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BVD86_08655	COG0583	DNA-binding transcription factor activity
BVD86_08665	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BVD86_08700	COG1944	ATP diphosphatase activity
BVD86_08720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVD86_08735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_08755	COG2814	Major facilitator Superfamily
BVD86_08760	COG1024	Enoyl-CoA hydratase
BVD86_08765	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_08775	COG1960	acyl-CoA dehydrogenase activity
BVD86_08800	COG0697	spore germination
BVD86_08835	COG4968	Prepilin-type N-terminal cleavage methylation domain
BVD86_08845	COG4796	Type ii and iii secretion system protein
BVD86_08880	COG2165	general secretion pathway protein
BVD86_08925	COG1113	amino acid transport
BVD86_08945	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_08965	COG0531	amino acid
BVD86_08975	COG1113	amino acid transport
BVD86_09005	COG3209	COG3209 Rhs family protein
BVD86_09010	COG3501	Rhs element vgr protein
BVD86_09025	COG4269	membrane
BVD86_09040	COG0582	viral genome integration into host DNA
BVD86_09100	COG2801	Transposase and inactivated derivatives
BVD86_09125	COG0583	DNA-binding transcription factor activity
BVD86_09145	COG0235	Class ii aldolase
BVD86_09150	COG0477	Major facilitator Superfamily
BVD86_09160	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_09170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVD86_09175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD86_09180	COG1113	amino acid transport
BVD86_09190	COG1522	sequence-specific DNA binding
BVD86_09215	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BVD86_09225	COG2207	Transcriptional regulator
BVD86_09255	COG1309	transcriptional regulator
BVD86_09270	COG0210	DNA helicase
BVD86_09370	COG1113	amino acid transport
BVD86_09390	COG2508	Transcriptional regulator
BVD86_09390	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BVD86_09405	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVD86_09405	COG1902	pentaerythritol trinitrate reductase activity
BVD86_09415	COG2203	Gaf domain
BVD86_09415	COG5001	Diguanylate cyclase
BVD86_09415	COG3706	GGDEF domain
BVD86_09415	COG4251	negative regulation of phosphorylation
BVD86_09425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVD86_09445	COG4172	Belongs to the ABC transporter superfamily
BVD86_09450	COG4239	(ABC) transporter, permease
BVD86_09455	COG4174	ABC transporter (Permease)
BVD86_09460	COG4166	transmembrane transport
BVD86_09465	COG1388	LysM domain
BVD86_09465	COG0741	lytic transglycosylase activity
BVD86_09465	COG0741	lytic transglycosylase activity
BVD86_09465	COG1388	LysM domain
BVD86_09470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVD86_09505	COG0583	DNA-binding transcription factor activity
BVD86_09510	COG1279	arginine transmembrane transporter activity
BVD86_09520	COG0789	Transcriptional regulator
BVD86_09530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_09535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_09540	COG0006	proline dipeptidase activity
BVD86_09875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVD86_09890	COG3384	dioxygenase
BVD86_09900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD86_09905	COG2878	Part of a membrane complex involved in electron transport
BVD86_09910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVD86_09935	COG0768	penicillin binding
BVD86_09940	COG0742	ribosomal rna small subunit methyltransferase
BVD86_09955	COG0830	nickel cation binding
BVD86_09965	COG0804	urea catabolic process
BVD86_09990	COG3015	lipoprotein NlpE involved in copper resistance
BVD86_10005	COG1253	flavin adenine dinucleotide binding
BVD86_10010	COG2851	Citrate transporter
BVD86_10060	COG1773	rubredoxin
BVD86_10065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_10070	COG2267	carboxylic ester hydrolase activity
BVD86_10075	COG0583	DNA-binding transcription factor activity
BVD86_10105	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BVD86_10110	COG4181	ATPase activity
BVD86_10155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVD86_10175	COG0306	phosphate transporter
BVD86_10185	COG3958	Transketolase
BVD86_10190	COG3959	Transketolase, thiamine diphosphate binding domain
BVD86_10195	COG2271	Major facilitator Superfamily
BVD86_10200	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_10205	COG0583	DNA-binding transcription factor activity
BVD86_10225	COG2223	nitrite transmembrane transporter activity
BVD86_10230	COG2207	Transcriptional regulator
BVD86_10235	COG2066	Belongs to the glutaminase family
BVD86_10240	COG0242	peptide deformylase activity
BVD86_10245	COG0477	Major facilitator Superfamily
BVD86_10260	COG0028	Belongs to the TPP enzyme family
BVD86_10275	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_10280	COG2267	carboxylic ester hydrolase activity
BVD86_10290	COG2271	Major facilitator Superfamily
BVD86_10305	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_10325	COG1414	Transcriptional regulator
BVD86_10340	COG1024	Enoyl-CoA hydratase
BVD86_10350	COG1215	transferase activity, transferring glycosyl groups
BVD86_10355	COG0726	polysaccharide deacetylase
BVD86_10355	COG1649	PFAM Uncharacterised BCR, COG1649
BVD86_10365	COG4681	YaeQ
BVD86_10385	COG1607	acyl-coa hydrolase
BVD86_10395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVD86_10400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVD86_10405	COG1309	transcriptional regulator
BVD86_10430	COG2040	homocysteine
BVD86_10435	COG0531	amino acid
BVD86_10490	COG1595	DNA-templated transcription, initiation
BVD86_10500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_10505	COG0477	Major facilitator Superfamily
BVD86_10550	COG0405	Gamma-glutamyltransferase
BVD86_10555	COG2814	Major facilitator Superfamily
BVD86_10565	COG2050	protein possibly involved in aromatic compounds catabolism
BVD86_10580	COG1090	epimerase
BVD86_10600	COG0420	3'-5' exonuclease activity
BVD86_10625	COG0735	belongs to the Fur family
BVD86_10630	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVD86_10635	COG2914	Belongs to the UPF0125 (RnfH) family
BVD86_10655	COG0121	glutamine amidotransferase
BVD86_10670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVD86_10680	COG0210	DNA helicase
BVD86_10685	COG2885	chlorophyll binding
BVD86_10690	COG0204	Acyl-transferase
BVD86_10705	COG2894	cell division
BVD86_10720	COG1280	lysine exporter protein (LysE YggA)
BVD86_10725	COG1674	ftsk spoiiie
BVD86_10730	COG0492	ferredoxin-NADP+ reductase activity
BVD86_10735	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVD86_10745	COG0456	acetyltransferase
BVD86_10760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVD86_10765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVD86_10775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVD86_10800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVD86_10800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVD86_10820	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_10825	COG4638	Rieske (2fe-2S)
BVD86_10840	COG0473	3-isopropylmalate dehydrogenase activity
BVD86_10845	COG0583	DNA-binding transcription factor activity
BVD86_10865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVD86_10905	COG0358	DNA primase activity
BVD86_10925	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BVD86_10955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVD86_10985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVD86_10995	COG0352	thiamine-phosphate diphosphorylase activity
BVD86_10995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVD86_10995	COG0351	phosphomethylpyrimidine kinase
BVD86_11000	COG1652	LysM domain
BVD86_11010	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_11025	COG1399	metal-binding, possibly nucleic acid-binding protein
BVD86_11030	COG3101	peptidyl-lysine hydroxylation
BVD86_11035	COG0009	L-threonylcarbamoyladenylate synthase
BVD86_11040	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BVD86_11045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVD86_11070	COG4106	trans-aconitate 2-methyltransferase activity
BVD86_11085	COG2226	methyltransferase
BVD86_11085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVD86_11085	COG0596	Alpha beta hydrolase
BVD86_11095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BVD86_11100	COG2223	nitrite transmembrane transporter activity
BVD86_11120	COG1196	nuclear chromosome segregation
BVD86_11130	COG0730	response to heat
BVD86_11145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVD86_11155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVD86_11205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVD86_11210	COG0489	protein tyrosine kinase activity
BVD86_11220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD86_11220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD86_11255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BVD86_11260	COG2081	HI0933 family
BVD86_11270	COG0668	transmembrane transport
BVD86_11290	COG0583	DNA-binding transcription factor activity
BVD86_11310	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVD86_11315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVD86_11345	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BVD86_11370	COG2199	diguanylate cyclase activity
BVD86_11380	COG2205	protein histidine kinase activity
BVD86_11385	COG0745	RESPONSE REGULATOR receiver
BVD86_11400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVD86_11460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_11465	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVD86_11475	COG0583	DNA-binding transcription factor activity
BVD86_11495	COG1473	amidohydrolase
BVD86_11530	COG0583	DNA-binding transcription factor activity
BVD86_11550	COG0583	DNA-binding transcription factor activity
BVD86_11555	COG1053	succinate dehydrogenase
BVD86_11570	COG1309	transcriptional regulator
BVD86_11580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVD86_11585	COG2814	Major facilitator Superfamily
BVD86_11590	COG1960	acyl-CoA dehydrogenase activity
BVD86_11595	COG0583	DNA-binding transcription factor activity
BVD86_11600	COG1063	alcohol dehydrogenase
BVD86_11630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVD86_11635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVD86_11640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVD86_11660	COG2132	Multicopper oxidase
BVD86_11670	COG0561	phosphatase activity
BVD86_11675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVD86_11685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BVD86_11700	COG1214	PFAM Peptidase M22, glycoprotease
BVD86_11760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVD86_11765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVD86_11770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVD86_11830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVD86_11840	COG1846	Transcriptional regulator
BVD86_11845	COG1764	response to oxidative stress
BVD86_11870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVD86_11870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVD86_11885	COG0037	tRNA processing
BVD86_11895	COG0248	Ppx GppA phosphatase
BVD86_11925	COG0072	phenylalanine-tRNA ligase activity
BVD86_11950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BVD86_11955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BVD86_11970	COG1238	metal cluster binding
BVD86_11975	COG0625	glutathione transferase activity
BVD86_11995	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_12000	COG3028	Belongs to the UPF0307 family
BVD86_12005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVD86_12025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVD86_12030	COG0617	tRNA 3'-terminal CCA addition
BVD86_12035	COG1555	photosystem II stabilization
BVD86_12040	COG3956	TIGRFAM MazG family protein
BVD86_12045	COG4221	oxidoreductase activity
BVD86_12050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVD86_12065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVD86_12070	COG2205	protein histidine kinase activity
BVD86_12070	COG0784	Response regulator, receiver
BVD86_12070	COG5002	protein histidine kinase activity
BVD86_12075	COG1024	Enoyl-CoA hydratase
BVD86_12080	COG2084	Dehydrogenase
BVD86_12085	COG3622	Belongs to the hyi family
BVD86_12105	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BVD86_12110	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BVD86_12115	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BVD86_12120	COG0697	spore germination
BVD86_12130	COG2814	Major facilitator Superfamily
BVD86_12135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVD86_12150	COG0583	DNA-binding transcription factor activity
BVD86_12160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVD86_12170	COG0084	hydrolase, TatD family'
BVD86_12185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVD86_12205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVD86_12210	COG0440	acetolactate synthase activity
BVD86_12215	COG0028	Belongs to the TPP enzyme family
BVD86_12235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_12240	COG1136	(ABC) transporter
BVD86_12240	COG0577	efflux transmembrane transporter activity
BVD86_12260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BVD86_12265	COG1162	GTPase activity
BVD86_12275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVD86_12295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVD86_12300	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_12340	COG2986	histidine ammonia-lyase
BVD86_12355	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_12365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVD86_12370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVD86_12390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVD86_12410	COG1426	Protein conserved in bacteria
BVD86_12445	COG0793	Belongs to the peptidase S41A family
BVD86_12460	COG2267	carboxylic ester hydrolase activity
BVD86_12470	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_12475	COG3265	gluconokinase activity
BVD86_12485	COG0800	Aldolase
BVD86_12500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVD86_12505	COG0857	belongs to the CobB CobQ family
BVD86_12505	COG0280	phosphate acetyltransferase
BVD86_12510	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BVD86_12510	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BVD86_12530	COG0740	serine-type endopeptidase activity
BVD86_12540	COG4774	siderophore transport
BVD86_12550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVD86_12560	COG2813	Specifically methylates the guanine in position
BVD86_12560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVD86_12660	COG0788	formyltetrahydrofolate deformylase activity
BVD86_12675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVD86_12680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVD86_12685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVD86_12685	COG4651	solute:proton antiporter activity
BVD86_12705	COG0724	RNA recognition motif
BVD86_12710	COG0210	DNA helicase
BVD86_12735	COG1733	regulation of RNA biosynthetic process
BVD86_12745	COG2900	Belongs to the SlyX family
BVD86_12760	COG1560	Kdo2-lipid A biosynthetic process
BVD86_12770	COG1301	dicarboxylic acid transport
BVD86_12825	COG0473	3-isopropylmalate dehydrogenase activity
BVD86_12850	COG0583	DNA-binding transcription factor activity
BVD86_12895	COG0583	DNA-binding transcription factor activity
BVD86_12905	COG0625	glutathione transferase activity
BVD86_12910	COG2378	regulation of single-species biofilm formation
BVD86_12915	COG0546	phosphoglycolate phosphatase activity
BVD86_12930	COG1530	ribonuclease E activity
BVD86_12950	COG0583	DNA-binding transcription factor activity
BVD86_12955	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_12960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVD86_12970	COG0534	Mate efflux family protein
BVD86_12985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVD86_13015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVD86_13015	COG0493	'glutamate synthase
BVD86_13025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BVD86_13030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVD86_13045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVD86_13055	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BVD86_13055	COG0644	oxidoreductase
BVD86_13065	COG4535	Mg2 and Co2 transporter CorC
BVD86_13075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVD86_13095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVD86_13105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BVD86_13115	COG0484	heat shock protein binding
BVD86_13120	COG0789	Transcriptional regulator
BVD86_13125	COG0598	Magnesium transport protein CorA
BVD86_13130	COG1185	polyribonucleotide nucleotidyltransferase activity
BVD86_13145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVD86_13150	COG1074	ATP-dependent DNA helicase activity
BVD86_13155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BVD86_13175	COG2226	methyltransferase
BVD86_13200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVD86_13215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVD86_13215	COG2111	Na H antiporter
BVD86_13220	COG1006	Multisubunit Na H antiporter MnhC subunit
BVD86_13225	COG0651	ATP synthesis coupled electron transport
BVD86_13235	COG2212	antiporter activity
BVD86_13245	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVD86_13255	COG0195	Participates in both transcription termination and antitermination
BVD86_13305	COG0237	dephospho-CoA kinase activity
BVD86_13315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVD86_13330	COG0497	DNA recombination
BVD86_13340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVD86_13375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVD86_13375	COG2169	Transcriptional regulator
BVD86_13380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVD86_13440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BVD86_13455	COG0326	Molecular chaperone. Has ATPase activity
BVD86_13470	COG2056	Na+-H+ antiporter family
BVD86_13540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVD86_13570	COG0546	phosphoglycolate phosphatase activity
BVD86_13575	COG1716	ATPase activity
BVD86_13620	COG0181	hydroxymethylbilane synthase activity
BVD86_13630	COG3275	phosphorelay sensor kinase activity
BVD86_13650	COG1538	Outer membrane efflux protein
BVD86_13660	COG0697	spore germination
BVD86_13685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVD86_13690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BVD86_13695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVD86_13700	COG0772	Belongs to the SEDS family
BVD86_13725	COG4974	Belongs to the 'phage' integrase family
BVD86_13730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVD86_13740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BVD86_13750	COG2197	response regulator
BVD86_13765	COG0793	Belongs to the peptidase S41A family
BVD86_13770	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BVD86_13775	COG0795	lipopolysaccharide-transporting ATPase activity
BVD86_13815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVD86_13815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVD86_13825	COG0004	ammonium transporteR
BVD86_13830	COG0347	Belongs to the P(II) protein family
BVD86_13840	COG0606	chelatase, subunit chli
BVD86_13845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_13850	COG0235	Class ii aldolase
BVD86_13855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_13875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVD86_13890	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_13900	COG0477	Major facilitator Superfamily
BVD86_13905	COG2860	membrane
BVD86_13915	COG1253	flavin adenine dinucleotide binding
BVD86_13925	COG2814	Major facilitator Superfamily
BVD86_13935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVD86_13975	COG0655	NAD(P)H dehydrogenase (quinone) activity
BVD86_13990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVD86_14055	COG0758	DNA mediated transformation
BVD86_14065	COG0697	spore germination
BVD86_14070	COG1309	transcriptional regulator
BVD86_14085	COG0386	Belongs to the glutathione peroxidase family
BVD86_14100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVD86_14110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVD86_14150	COG1121	(ABC) transporter
BVD86_14155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVD86_14160	COG1280	lysine exporter protein (LysE YggA)
BVD86_14165	COG2837	iron assimilation
BVD86_14170	COG0281	malic enzyme
BVD86_14215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVD86_14220	COG0519	Catalyzes the synthesis of GMP from XMP
BVD86_14220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVD86_14225	COG4399	Belongs to the UPF0754 family
BVD86_14230	COG2259	Doxx family
BVD86_14235	COG0586	Pfam SNARE associated Golgi protein
BVD86_14250	COG1192	Involved in chromosome partitioning
BVD86_14260	COG0271	Belongs to the BolA IbaG family
BVD86_14300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_14300	COG3321	synthase
BVD86_14300	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_14300	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_14300	COG0300	oxidoreductase activity
BVD86_14305	COG1960	acyl-CoA dehydrogenase activity
BVD86_14310	COG0318	PFAM AMP-dependent synthetase and ligase
BVD86_14315	COG2197	response regulator
BVD86_14325	COG3916	Acyl-homoserine-lactone synthase
BVD86_14330	COG0477	Major facilitator Superfamily
BVD86_14335	COG1024	Enoyl-CoA hydratase
BVD86_14340	COG1024	Enoyl-CoA hydratase
BVD86_14345	COG1960	acyl-CoA dehydrogenase activity
BVD86_14350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVD86_14370	COG1113	amino acid transport
BVD86_14375	COG1113	amino acid transport
BVD86_14380	COG0251	oxidation-reduction process
BVD86_14395	COG1522	sequence-specific DNA binding
BVD86_14420	COG0564	pseudouridine synthase activity
BVD86_14460	COG1051	belongs to the nudix hydrolase family
BVD86_14480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVD86_14495	COG1802	Transcriptional regulator
BVD86_14505	COG1448	Aminotransferase
BVD86_14510	COG0277	FAD linked oxidase domain protein
BVD86_14520	COG2186	Transcriptional regulator
BVD86_14530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVD86_14535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVD86_14550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVD86_14560	COG0110	maltose O-acetyltransferase activity
BVD86_14580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVD86_14615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVD86_14620	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVD86_14625	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVD86_14630	COG1596	polysaccharide export
BVD86_14655	COG0728	peptidoglycan biosynthetic process
BVD86_14660	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVD86_14720	COG0546	phosphoglycolate phosphatase activity
BVD86_14725	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_14740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BVD86_14740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVD86_14745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_14750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVD86_14755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_14760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVD86_14765	COG1116	anion transmembrane transporter activity
BVD86_14770	COG1309	transcriptional regulator
BVD86_14775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVD86_14785	COG0196	riboflavin kinase activity
BVD86_14790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVD86_14800	COG1047	Peptidyl-prolyl cis-trans
BVD86_14840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVD86_14905	COG2951	lytic endotransglycosylase activity
BVD86_14910	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVD86_14925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVD86_14935	COG0671	phosphoesterase, PA-phosphatase related
BVD86_14940	COG0861	Integral membrane protein TerC family
BVD86_14950	COG0754	glutathionylspermidine amidase activity
BVD86_14960	COG0402	S-adenosylhomocysteine deaminase activity
BVD86_14975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVD86_14980	COG1230	cation diffusion facilitator family transporter
BVD86_14995	COG0706	membrane insertase activity
BVD86_15010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BVD86_15020	COG0592	DNA-directed DNA polymerase activity
BVD86_15030	COG0187	DNA topoisomerase II activity
BVD86_15045	COG0488	(ABC) transporter
BVD86_15075	COG0596	Alpha beta hydrolase
BVD86_15080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BVD86_15085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVD86_15120	COG0625	glutathione transferase activity
BVD86_15130	COG0733	neurotransmitter:sodium symporter activity
BVD86_15170	COG2233	PERMEase
BVD86_15185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_15220	COG2814	Major facilitator Superfamily
BVD86_15225	COG0656	L-ascorbic acid biosynthetic process
BVD86_15230	COG0583	DNA-binding transcription factor activity
BVD86_15245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVD86_15250	COG1064	alcohol dehydrogenase
BVD86_15255	COG2818	Glycosylase
BVD86_15270	COG1194	a g-specific adenine glycosylase
BVD86_15285	COG5487	UPF0391 membrane protein
BVD86_15290	COG2983	Belongs to the UPF0260 family
BVD86_15295	COG2133	pyrroloquinoline quinone binding
BVD86_15300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVD86_15305	COG2116	formate transmembrane transporter activity
BVD86_15325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVD86_15330	COG1335	isochorismatase
BVD86_15335	COG0385	Bile acid
BVD86_15340	COG0534	Mate efflux family protein
BVD86_15345	COG1683	Conserved Protein
BVD86_15360	COG0346	lactoylglutathione lyase activity
BVD86_15365	COG0625	glutathione transferase activity
BVD86_15375	COG1113	amino acid transport
BVD86_15385	COG0523	cobalamin synthesis protein
BVD86_15395	COG2188	Transcriptional regulator
BVD86_15425	COG0010	Belongs to the arginase family
BVD86_15435	COG0546	phosphoglycolate phosphatase activity
BVD86_15440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVD86_15450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVD86_15460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVD86_15465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVD86_15570	COG0534	Mate efflux family protein
BVD86_15575	COG0436	Aminotransferase
BVD86_15580	COG2733	membrane
BVD86_15595	COG2918	glutathione biosynthetic process
BVD86_15605	COG3501	Rhs element vgr protein
BVD86_15645	COG3150	esterase
BVD86_15655	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BVD86_15665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVD86_15675	COG2233	PERMEase
BVD86_15680	COG2351	hydroxyisourate hydrolase activity
BVD86_15715	COG3706	GGDEF domain
BVD86_15730	COG1393	Belongs to the ArsC family
BVD86_15735	COG0708	Exodeoxyribonuclease III
BVD86_15765	COG0189	ligase activity
BVD86_15785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVD86_15795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVD86_15810	COG4942	peptidase
BVD86_15820	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVD86_15830	COG2119	membrane
BVD86_15840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_15840	COG0426	domain, Protein
BVD86_15860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVD86_15880	COG1902	pentaerythritol trinitrate reductase activity
BVD86_15885	COG1519	Transferase
BVD86_15890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVD86_15895	COG0668	transmembrane transport
BVD86_15905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVD86_15910	COG1335	isochorismatase
BVD86_15915	COG1522	sequence-specific DNA binding
BVD86_15940	COG0784	Response regulator, receiver
BVD86_15940	COG2205	protein histidine kinase activity
BVD86_15940	COG2198	Histidine kinase
BVD86_15945	COG3162	membrane
BVD86_15950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVD86_15960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BVD86_15970	COG3706	GGDEF domain
BVD86_15980	COG1309	transcriptional regulator
BVD86_16000	COG4221	oxidoreductase activity
BVD86_16010	COG0351	phosphomethylpyrimidine kinase
BVD86_16010	COG0352	thiamine-phosphate diphosphorylase activity
BVD86_16010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BVD86_16020	COG2814	Major facilitator Superfamily
BVD86_16035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BVD86_16055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVD86_16060	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_16070	COG1335	isochorismatase
BVD86_16105	COG2814	Major facilitator Superfamily
BVD86_16110	COG0583	DNA-binding transcription factor activity
BVD86_16130	COG0667	Aldo Keto reductase
BVD86_16150	COG1309	transcriptional regulator
BVD86_16175	COG1733	regulation of RNA biosynthetic process
BVD86_16180	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_16200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BVD86_16205	COG2207	Transcriptional regulator
BVD86_16265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVD86_16280	COG0697	spore germination
BVD86_16300	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BVD86_16310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BVD86_16340	COG0427	acetyl-CoA hydrolase
BVD86_16350	COG2205	protein histidine kinase activity
BVD86_16355	COG0745	RESPONSE REGULATOR receiver
BVD86_16365	COG0659	secondary active sulfate transmembrane transporter activity
BVD86_16370	COG4221	oxidoreductase activity
BVD86_16380	COG0488	(ABC) transporter
BVD86_16465	COG0833	amino acid
BVD86_16510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVD86_16515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVD86_16530	COG2226	methyltransferase
BVD86_16580	COG0070	glutamate synthase
BVD86_16580	COG0069	glutamate synthase activity
BVD86_16580	COG0067	glutamate synthase
BVD86_16585	COG0493	'glutamate synthase
BVD86_16595	COG1704	LemA family
BVD86_16600	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BVD86_16615	COG3307	-O-antigen
BVD86_16635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVD86_16645	COG0194	GDP metabolic process
BVD86_16695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVD86_16705	COG0335	large ribosomal subunit rRNA binding
BVD86_16715	COG5380	lipid catabolic process
BVD86_16720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVD86_16735	COG5006	permease, DMT superfamily
BVD86_16740	COG5006	permease, DMT superfamily
BVD86_16745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVD86_16750	COG0277	FAD linked oxidase domain protein
BVD86_16760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BVD86_16765	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_16780	COG1289	transmembrane transporter activity
BVD86_16790	COG0628	permease
BVD86_16795	COG1192	Involved in chromosome partitioning
BVD86_16825	COG0833	amino acid
BVD86_16830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVD86_16835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVD86_16845	COG1012	belongs to the aldehyde dehydrogenase family
BVD86_16885	COG0583	DNA-binding transcription factor activity
BVD86_16915	COG0752	glycyl-tRNA synthetase alpha subunit
BVD86_16945	COG4109	DRTGG domain
BVD86_16950	COG1983	PspC domain protein
BVD86_16960	COG1960	acyl-CoA dehydrogenase activity
BVD86_16975	COG0408	coproporphyrinogen oxidase activity
BVD86_16995	COG0513	Belongs to the DEAD box helicase family
BVD86_17005	COG1127	ABC transporter
BVD86_17010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVD86_17020	COG2854	intermembrane phospholipid transfer
BVD86_17030	COG0598	Magnesium transport protein CorA
BVD86_17040	COG0494	nUDIX hydrolase
BVD86_17045	COG1040	competence protein
BVD86_17050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVD86_17065	COG2937	Belongs to the GPAT DAPAT family
BVD86_17070	COG1946	Acyl-CoA thioesterase
BVD86_17075	COG1301	dicarboxylic acid transport
BVD86_17090	COG1959	2 iron, 2 sulfur cluster binding
BVD86_17095	COG1017	nitric oxide dioxygenase activity
BVD86_17095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVD86_17100	COG0433	COG0433 Predicted ATPase
BVD86_17105	COG0626	cystathionine gamma-synthase activity
BVD86_17120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVD86_17125	COG0088	Forms part of the polypeptide exit tunnel
BVD86_17225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVD86_17235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVD86_17260	COG1960	acyl-CoA dehydrogenase activity
BVD86_17265	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BVD86_17295	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BVD86_17300	COG0339	signal peptide processing
BVD86_17305	COG0557	exoribonuclease II activity
BVD86_17350	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVD86_17355	COG1295	ribonuclease BN
BVD86_17390	COG1702	phosphate starvation-inducible protein PhoH
BVD86_17400	COG1196	nuclear chromosome segregation
BVD86_17400	COG0739	heme binding
BVD86_17400	COG0741	lytic transglycosylase activity
BVD86_17430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVD86_17435	COG1183	phosphatidylcholine synthase activity
BVD86_17480	COG1960	acyl-CoA dehydrogenase activity
BVD86_17485	COG1309	transcriptional regulator
BVD86_17500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVD86_17505	COG1960	acyl-CoA dehydrogenase activity
BVD86_17525	COG2969	positive regulation of protein catabolic process
BVD86_17535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVD86_17540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVD86_17545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVD86_17550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVD86_17555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVD86_17575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVD86_17585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVD86_17590	COG1408	metallophosphoesterase
BVD86_17595	COG2885	chlorophyll binding
BVD86_17595	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVD86_17600	COG2199	diguanylate cyclase activity
BVD86_17655	COG3453	Protein conserved in bacteria
BVD86_17655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVD86_17670	COG1607	acyl-coa hydrolase
BVD86_17705	COG2350	Protein conserved in bacteria
BVD86_17720	COG3781	membrane
BVD86_17730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVD86_17735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVD86_17745	COG1862	Preprotein translocase
BVD86_17825	COG3646	Phage regulatory protein
BVD86_17995	COG4695	Portal protein
BVD86_18010	COG2205	protein histidine kinase activity
BVD86_18010	COG2198	Histidine kinase
BVD86_18010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVD86_18010	COG0784	Response regulator, receiver
BVD86_18015	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BVD86_18035	COG0726	polysaccharide deacetylase
BVD86_18040	COG0463	Glycosyl transferase, family 2
BVD86_18045	COG0438	transferase activity, transferring glycosyl groups
BVD86_18110	COG1960	acyl-CoA dehydrogenase activity
BVD86_18115	COG1960	acyl-CoA dehydrogenase activity
BVD86_18125	COG2205	protein histidine kinase activity
BVD86_18130	COG0745	RESPONSE REGULATOR receiver
BVD86_18140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BVD86_18160	COG2096	Adenosyltransferase
BVD86_18165	COG4206	TonB-dependent receptor
BVD86_18175	COG0133	tryptophan synthase activity
BVD86_18210	COG0285	dihydrofolate synthase activity
BVD86_18230	COG0450	alkyl hydroperoxide reductase
BVD86_18245	COG0477	Major facilitator Superfamily
BVD86_18250	COG1272	protein, Hemolysin III
BVD86_18260	COG2153	protein acetylation
BVD86_18280	COG0183	Belongs to the thiolase family
BVD86_18285	COG2207	Transcriptional regulator
BVD86_18305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVD86_18325	COG0183	Belongs to the thiolase family
BVD86_18335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVD86_18335	COG2885	chlorophyll binding
BVD86_18340	COG1690	Belongs to the RtcB family
BVD86_18345	COG0833	amino acid
BVD86_18355	COG2233	PERMEase
BVD86_18375	COG4580	involved in the transport of maltose and maltodextrins
BVD86_18390	COG2094	Belongs to the DNA glycosylase MPG family
BVD86_18395	COG4772	TonB-dependent receptor
BVD86_18400	COG1902	pentaerythritol trinitrate reductase activity
BVD86_18415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVD86_18420	COG0354	folic acid binding
BVD86_18440	COG2233	PERMEase
BVD86_18445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVD86_18450	COG0251	oxidation-reduction process
BVD86_18455	COG1335	isochorismatase
BVD86_18460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVD86_18465	COG0778	Nitroreductase
BVD86_18470	COG0596	Alpha beta hydrolase
BVD86_18475	COG3189	MarR family transcriptional regulator
BVD86_18480	COG2824	Alkylphosphonate utilization operon protein PhnA
BVD86_18485	COG3422	double-strand break repair
BVD86_18525	COG0840	transmembrane signaling receptor activity
BVD86_18545	COG5510	response to toxic substance
BVD86_18555	COG2832	Protein of unknown function (DUF454)
BVD86_18560	COG1376	ErfK ybiS ycfS ynhG family protein
BVD86_18600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BVD86_18610	COG1289	transmembrane transporter activity
BVD86_18615	COG2814	Major facilitator Superfamily
BVD86_18640	COG1115	amino acid carrier protein
BVD86_18645	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVD86_18650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVD86_18655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BVD86_18680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVD86_18690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVD86_18695	COG1077	Cell shape determining protein MreB Mrl
BVD86_18700	COG1792	Involved in formation and maintenance of cell shape
BVD86_18705	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BVD86_18710	COG0424	maF-like protein
BVD86_18715	COG1530	ribonuclease E activity
BVD86_18725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVD86_18745	COG2249	NAD(P)H dehydrogenase (quinone) activity
BVD86_18770	COG2207	Transcriptional regulator
BVD86_18810	COG1113	amino acid transport
BVD86_18815	COG2828	Protein conserved in bacteria
BVD86_18820	COG0142	geranyltranstransferase activity
BVD86_18825	COG2315	Protein conserved in bacteria
BVD86_18840	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVD86_18865	COG2194	sulfuric ester hydrolase activity
BVD86_18870	COG0745	RESPONSE REGULATOR receiver
BVD86_18875	COG0642	Histidine kinase
BVD86_18885	COG0004	ammonium transporteR
BVD86_18890	COG0583	DNA-binding transcription factor activity
BVD86_18915	COG0525	valine-tRNA ligase activity
BVD86_18925	COG1028	Short-chain dehydrogenase reductase Sdr
BVD86_18935	COG0393	Putative heavy-metal-binding
BVD86_18940	COG0393	Putative heavy-metal-binding
BVD86_18945	COG1538	Outer membrane efflux protein
BVD86_18955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_18960	COG0671	phosphoesterase, PA-phosphatase related
BVD86_18985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVD86_19000	COG1648	precorrin-2 dehydrogenase activity
BVD86_19000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVD86_19005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVD86_19040	COG0531	amino acid
BVD86_19055	COG0321	lipoyl(octanoyl) transferase activity
BVD86_19060	COG2921	Belongs to the UPF0250 family
BVD86_19105	COG2009	succinate dehydrogenase
BVD86_19110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BVD86_19115	COG1053	succinate dehydrogenase
BVD86_19120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVD86_19145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVD86_19165	COG2354	Protein conserved in bacteria
BVD86_19170	COG2321	neutral zinc metallopeptidase
BVD86_19190	COG2843	Capsule synthesis protein
BVD86_19210	COG0589	response to stress
BVD86_19220	COG0251	oxidation-reduction process
BVD86_19240	COG0505	Belongs to the CarA family
BVD86_19275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVD86_19280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVD86_19335	COG0477	Major facilitator Superfamily
BVD86_19340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVD86_19360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVD86_19385	COG0584	glycerophosphoryl diester phosphodiesterase
BVD86_19405	COG0741	lytic transglycosylase activity
BVD86_19430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVD86_19450	COG0583	DNA-binding transcription factor activity
BVD86_19500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_19505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVD86_19510	COG0778	Nitroreductase
BVD86_19525	COG1929	Belongs to the glycerate kinase type-1 family
BVD86_19530	COG0243	molybdopterin cofactor binding
BVD86_19535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVD86_19540	COG3339	Conserved Protein
BVD86_19565	COG1115	amino acid carrier protein
BVD86_19570	COG1113	amino acid transport
BVD86_19580	COG0019	diaminopimelate decarboxylase activity
BVD86_19595	COG2267	carboxylic ester hydrolase activity
BVD86_19600	COG1280	lysine exporter protein (LysE YggA)
BVD86_19605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BVD86_19635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVD86_19660	COG0697	spore germination
BVD86_19665	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVD86_19670	COG1136	(ABC) transporter
BVD86_19675	COG2333	competence protein COMEC
BVD86_19675	COG0658	competence protein
BVD86_19685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVD86_19685	COG0616	signal peptide processing
BVD86_19690	COG0596	Alpha beta hydrolase
BVD86_19695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVD86_19705	COG0628	permease
BVD86_19760	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
