locus-tag	class	description
E3H47_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E3H47_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E3H47_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3H47_00025	ENOG4105E2A	Dehydrogenase
E3H47_00035	ENOG4105C5H	ABC transporter
E3H47_00040	ENOG4108821	RND type efflux pump
E3H47_00045	ENOG4108821	RND type efflux pump
E3H47_00050	ENOG4108821	RND type efflux pump
E3H47_00065	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E3H47_00070	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E3H47_00085	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E3H47_00090	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E3H47_00095	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E3H47_00100	ENOG4105DTN	riboflavin biosynthesis protein ribF
E3H47_00120	ENOG4108VM9	ABC, transporter
E3H47_00125	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E3H47_00130	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
E3H47_00135	ENOG4105GVF	(ABC) transporter
E3H47_00140	ENOG4105GVF	(ABC) transporter
E3H47_00145	ENOG4107QZM	n-acetylglutamate synthase
E3H47_00160	ENOG4105UBK	short-chain dehydrogenase reductase
E3H47_00165	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3H47_00180	ENOG4105R8C	Transcriptional regulator
E3H47_00185	ENOG4105EJ2	Transcriptional regulator
E3H47_00190	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
E3H47_00200	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E3H47_00210	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E3H47_00220	ENOG4105CJR	Integral membrane protein (MviN
E3H47_00235	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3H47_00240	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E3H47_00245	ENOG4105D75	Capsular exopolysaccharide family
E3H47_00255	ENOG4105DAY	polysaccharide export protein
E3H47_00260	ENOG4107QQG	Dehydrogenase
E3H47_00305	ENOG4105CGN	Glycosyl transferase (Group 1
E3H47_00310	ENOG4105D3Q	Sugar transferase
E3H47_00315	ENOG4107WZ3	Transferase
E3H47_00320	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E3H47_00330	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E3H47_00335	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E3H47_00345	ENOG4105CMR	udp-glucose 4-epimerase
E3H47_00350	ENOG4107QKV	phosphomannomutase
E3H47_00365	ENOG4105M85	Bola protein
E3H47_00380	ENOG4105DQR	SNARE associated Golgi
E3H47_00385	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3H47_00390	ENOG4105EUB	pirin domain protein
E3H47_00395	ENOG4108K3A	Glutathione S-transferase
E3H47_00415	ENOG4107R1I	NAD-dependent malic enzyme
E3H47_00420	ENOG4105CS6	Rhs element vgr protein
E3H47_00480	ENOG4105EZR	dyp-type peroxidase family protein
E3H47_00485	ENOG4105FAV	ABC, transporter
E3H47_00490	ENOG4105FDK	ABC transporter
E3H47_00515	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E3H47_00550	ENOG4105C26	Dehydrogenase
E3H47_00565	ENOG4108V06	Glutathione peroxidase
E3H47_00580	ENOG4105SX7	Transporter
E3H47_00590	ENOG4105C79	DNA protecting protein DprA
E3H47_00595	ENOG4108WZM	domain protein
E3H47_00640	ENOG4105D2S	major facilitator superfamily
E3H47_00650	ENOG4105D94	Major Facilitator Superfamily
E3H47_00655	ENOG4105CCT	upf0313 protein
E3H47_00670	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E3H47_00690	ENOG4108URH	decarboxylase
E3H47_00695	ENOG4105EE5	Membrane protein terC
E3H47_00700	ENOG4105K5B	UPF0225 protein
E3H47_00705	ENOG4105EN6	Membrane
E3H47_00710	ENOG41079KZ	Major Facilitator Superfamily
E3H47_00715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3H47_00720	ENOG4105CEY	Amp-dependent synthetase and ligase
E3H47_00735	ENOG4105F0N	pyrophosphate phospho-hydrolase
E3H47_00740	ENOG4105EPF	Outer membrane porin
E3H47_00750	ENOG4105C0P	Mg chelatase subunit ChlI
E3H47_00760	ENOG4108YZA	Nitrogen regulatory protein pii
E3H47_00765	ENOG4105BZU	Histidine kinase
E3H47_00775	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E3H47_00805	ENOG4108M8S	permease YjgP YjgQ family protein
E3H47_00810	ENOG4108K5H	permease YjgP YjgQ family protein
E3H47_00815	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E3H47_00820	ENOG4105CN1	protease
E3H47_00825	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3H47_00830	ENOG4105BZU	Histidine kinase
E3H47_00840	ENOG41061WM	D-Alanyl-D-Alanine
E3H47_00850	ENOG4105D6E	homoserine dehydrogenase
E3H47_00860	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3H47_00870	ENOG4105CE1	Ferrous iron transport protein b
E3H47_00885	ENOG4105CNI	cell division protein FtsW
E3H47_00895	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E3H47_00900	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E3H47_00905	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E3H47_00910	ENOG41087AY	ADP-Ribose pyrophosphatase
E3H47_00930	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E3H47_00945	ENOG4108HRK	Histidine kinase
E3H47_00950	ENOG4108NEV	two component transcriptional regulator, LytTR family
E3H47_00955	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E3H47_00980	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
E3H47_00995	ENOG4105GVR	general secretion pathway protein D
E3H47_01000	ENOG4105TV9	FHA Domain-Containing protein
E3H47_01005	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3H47_01045	ENOG4105PM1	preprotein translocase subunit SecE
E3H47_01050	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E3H47_01075	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3H47_01080	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3H47_01095	ENOG4105D3Y	Na H antiporter
E3H47_01105	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E3H47_01125	ENOG4107ZXU	DSBA oxidoreductase
E3H47_01155	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E3H47_01165	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E3H47_01170	ENOG4105BZ1	(ABC) transporter
E3H47_01200	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E3H47_01210	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E3H47_01220	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E3H47_01225	ENOG4108TVT	permease
E3H47_01230	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E3H47_01245	ENOG4107QHF	type ii secretion system protein e
E3H47_01255	ENOG4107EJC	Preprotein translocase subunit SecG
E3H47_01275	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
E3H47_01280	ENOG4105CHV	Transcription elongation factor NusA
E3H47_01295	ENOG4105KJM	monovalent cation h antiporter subunit g
E3H47_01300	ENOG4105W4C	monovalent cation H antiporter subunit F
E3H47_01305	ENOG4105SC1	monovalent cation H antiporter subunit E
E3H47_01310	ENOG4107R4Z	monovalent cation h antiporter subunit d
E3H47_01315	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E3H47_01320	ENOG4105D65	subunit l
E3H47_01335	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E3H47_01340	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E3H47_01360	ENOG4105CSR	polyphosphate kinase 2
E3H47_01370	ENOG4105DSY	exodeoxyribonuclease V, gamma
E3H47_01375	ENOG4107QKA	exodeoxyribonuclease V beta
E3H47_01380	ENOG4107QYX	exodeoxyribonuclease v alpha
E3H47_01390	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E3H47_01395	ENOG4105D7N	magnesium and cobalt transport protein CorA
E3H47_01405	ENOG4105DVC	DnaJ domain protein
E3H47_01415	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E3H47_01425	ENOG4105C25	Primosomal protein n'
E3H47_01430	ENOG4105D7Q	type ii secretion system
E3H47_01435	ENOG4108VAU	general secretion pathway protein G
E3H47_01445	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
E3H47_01450	ENOG4108JU5	Magnesium and cobalt efflux protein
E3H47_01460	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E3H47_01470	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E3H47_01480	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E3H47_01495	ENOG4105C5X	domain protein
E3H47_01505	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E3H47_01515	ENOG4105BZ8	glutamate synthase
E3H47_01530	ENOG4105WMR	Protein CrcB homolog
E3H47_01545	ENOG4107QI1	Mate efflux family protein
E3H47_01555	ENOG4105CSA	Coproporphyrinogen iii oxidase
E3H47_01590	ENOG4105C03	ribonuclease
E3H47_01600	ENOG4105EI2	Pseudouridine synthase
E3H47_01605	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3H47_01610	ENOG4105IKQ	hydratase
E3H47_01615	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
E3H47_01620	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
E3H47_01645	ENOG4108W5M	transcriptional regulator
E3H47_01650	ENOG4105FUY	alpha subunit
E3H47_01665	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
E3H47_01670	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
E3H47_01675	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
E3H47_01700	ENOG4105CH6	catalase
E3H47_01710	ENOG4105CSU	acyl-Coa dehydrogenase
E3H47_01720	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E3H47_01725	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E3H47_01740	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E3H47_01755	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E3H47_01795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E3H47_01810	ENOG4105D1S	lipid A biosynthesis
E3H47_01815	ENOG4108UVJ	appr-1-p processing domain protein
E3H47_01820	ENOG4105C5H	ABC transporter
E3H47_01825	ENOG41069P5	Protein slyX homolog
E3H47_01840	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E3H47_01855	ENOG4105BZW	Glycerate kinase
E3H47_01860	ENOG4105C4R	Atp-dependent dna helicase
E3H47_01865	ENOG4105VFU	Rna-binding protein
E3H47_01880	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E3H47_01885	ENOG4105W0E	50S ribosomal protein L33
E3H47_01890	ENOG4105KDC	50s ribosomal protein l28
E3H47_01895	ENOG4107RGH	Aldehyde dehydrogenase
E3H47_01900	ENOG41062JF	Transcriptional regulator
E3H47_01905	ENOG4105CIY	formyltetrahydrofolate deformylase
E3H47_01940	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
E3H47_02025	ENOG4105DWV	Homoserine O-trans-acetylase
E3H47_02030	ENOG4105DWV	Homoserine O-trans-acetylase
E3H47_02035	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E3H47_02045	ENOG4108ESX	Receptor
E3H47_02055	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E3H47_02070	ENOG4107GFK	fumarate
E3H47_02080	ENOG4108DNC	Involved in acetate metabolism (By similarity)
E3H47_02085	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E3H47_02100	ENOG4106HB6	Alpha beta hydrolase
E3H47_02115	ENOG4105CN1	protease
E3H47_02130	ENOG4105WVQ	Fe-S assembly protein IscX
E3H47_02150	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E3H47_02160	ENOG4105CUT	histidyl-tRNA synthetase
E3H47_02170	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E3H47_02185	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3H47_02190	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E3H47_02195	ENOG4105VIE	preprotein translocase, subunit YajC
E3H47_02205	ENOG4108V0P	LemA family
E3H47_02230	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E3H47_02235	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E3H47_02245	ENOG4107BJW	polysaccharide deacetylase
E3H47_02260	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E3H47_02265	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E3H47_02275	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E3H47_02305	ENOG4105UGU	tonB-dependent Receptor
E3H47_02330	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E3H47_02335	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3H47_02340	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E3H47_02345	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E3H47_02370	ENOG4105C7K	acetolactate synthase
E3H47_02375	ENOG4108ZP8	Acetolactate synthase small subunit
E3H47_02385	ENOG4105BZU	Histidine kinase
E3H47_02390	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E3H47_02405	ENOG4105EYA	deoxyribonuclease
E3H47_02410	ENOG4107QM5	aconitate hydratase
E3H47_02415	ENOG4105CUZ	uba thif-type nad fad binding protein
E3H47_02420	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3H47_02435	ENOG4106UX7	integral membrane protein
E3H47_02440	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E3H47_02445	ENOG4105W8H	transhydrogenase (subunit alpha
E3H47_02450	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E3H47_02460	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E3H47_02470	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
E3H47_02475	ENOG4105BZU	Histidine kinase
E3H47_02480	ENOG4105C6T	cysteine synthase
E3H47_02495	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3H47_02505	ENOG4105DXN	mazG family
E3H47_02510	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
E3H47_02515	ENOG4105DJ0	Poly(A) Polymerase
E3H47_02520	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E3H47_02530	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E3H47_02535	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E3H47_02540	ENOG41080Z8	PHOSPHOCARRIER protein
E3H47_02545	ENOG4105N42	UPF0307 protein
E3H47_02560	ENOG4105CEY	Amp-dependent synthetase and ligase
E3H47_02580	ENOG4105CYM	Glutathione S-transferase
E3H47_02585	ENOG4105W39	Membrane
E3H47_02605	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E3H47_02625	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E3H47_02640	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E3H47_02650	ENOG4105C9X	ppx gppa phosphatase
E3H47_02660	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E3H47_02665	ENOG4105II7	pyrroline-5-carboxylate reductase
E3H47_02670	ENOG4108VIA	integral membrane protein
E3H47_02675	ENOG4105C2M	dna polymerase I
E3H47_02695	ENOG4107QHF	type ii secretion system protein e
E3H47_02700	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E3H47_02755	ENOG4105KB2	stringent starvation protein b
E3H47_02760	ENOG4107MKT	Stringent starvation protein a
E3H47_02765	ENOG4108UJD	30S ribosomal protein S9
E3H47_02780	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E3H47_02785	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E3H47_02790	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E3H47_02800	ENOG41067MG	lrgb family
E3H47_02810	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E3H47_02820	ENOG4107RZC	phospholipase d
E3H47_02830	ENOG4105CSH	Transporter
E3H47_02835	ENOG4108UT2	hemolysin iii
E3H47_02845	ENOG4108NRW	Phospholipase, patatin family
E3H47_02855	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3H47_02860	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_02865	ENOG4108R6W	Transcriptional regulator, ARAC family
E3H47_02875	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E3H47_02885	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E3H47_02895	ENOG4105EM2	membrane
E3H47_02900	ENOG4105C2C	drug resistance transporter, Bcr CflA
E3H47_02915	ENOG4105D6U	Sodium Glutamate Symporter
E3H47_02920	ENOG4105BZG	amino acid carrier protein
E3H47_02925	ENOG4105FGV	Chromate
E3H47_02930	ENOG4105D78	K07001 NTE family protein
E3H47_02945	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
E3H47_02955	ENOG4105E39	Enoyl-CoA hydratase
E3H47_02960	ENOG4107QX3	carboxylase
E3H47_02965	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_02970	ENOG4105PF9	Transcriptional regulator
E3H47_02975	ENOG4105CEY	Amp-dependent synthetase and ligase
E3H47_03005	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E3H47_03015	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E3H47_03020	ENOG4105DFF	Rod shape-determining protein mreb
E3H47_03025	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E3H47_03030	ENOG4105VQ7	Rod shape-determining protein MreD
E3H47_03035	ENOG4108Z03	MAF-like protein
E3H47_03040	ENOG4105C03	ribonuclease
E3H47_03045	ENOG4105D8T	Acyltransferase
E3H47_03055	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
E3H47_03075	ENOG4105DHQ	Histidine kinase
E3H47_03080	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3H47_03085	ENOG4105DIJ	Phosphoethanolamine transferase
E3H47_03095	ENOG4105C85	amino acid
E3H47_03100	ENOG4105C7F	AcnD-accessory protein PrpF
E3H47_03105	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E3H47_03110	ENOG4105CTB	Polyprenyl synthetase
E3H47_03125	ENOG4105C4R	Atp-dependent dna helicase
E3H47_03140	ENOG4105F5W	AtP-binding protein
E3H47_03190	ENOG4105D78	K07001 NTE family protein
E3H47_03215	ENOG4108WUH	Transcriptional regulator, TetR family
E3H47_03240	ENOG4105CDA	abc transporter atp-binding protein
E3H47_03245	ENOG4105DRP	amino acid AbC transporter
E3H47_03250	ENOG4105EAD	ABC transporter
E3H47_03255	ENOG4107RP9	extracellular solute-binding protein, family 3
E3H47_03280	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E3H47_03300	ENOG4105K8R	UPF0145 protein
E3H47_03305	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E3H47_03310	ENOG4105BZS	acriflavin resistance protein
E3H47_03315	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E3H47_03320	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E3H47_03335	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E3H47_03340	ENOG4105K46	50S ribosomal protein l27
E3H47_03345	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E3H47_03380	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E3H47_03385	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E3H47_03390	ENOG4105CUB	amino acid
E3H47_03395	ENOG4105C0A	alcohol dehydrogenase
E3H47_03405	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E3H47_03415	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3H47_03430	ENOG4107T5V	SNARE associated Golgi
E3H47_03450	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3H47_03470	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E3H47_03500	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E3H47_03515	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E3H47_03520	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3H47_03525	ENOG4105C34	Pseudouridine synthase
E3H47_03530	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E3H47_03545	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E3H47_03575	ENOG4105C4K	Nad synthetase
E3H47_03590	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E3H47_03595	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E3H47_03605	ENOG4105E33	succinate dehydrogenase
E3H47_03610	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E3H47_03615	ENOG4105C7S	Dehydrogenase
E3H47_03620	ENOG4107QN2	dihydrolipoyl dehydrogenase
E3H47_03630	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E3H47_03640	ENOG4105CKW	Inner membrane protein yedI
E3H47_03645	ENOG4105CGZ	zinc metallopeptidase
E3H47_03655	ENOG4105EEQ	Na H antiporter
E3H47_03670	ENOG4105EQK	-acetyltransferase
E3H47_03680	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E3H47_03685	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E3H47_03700	ENOG4105HBR	Rna-binding protein
E3H47_03710	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E3H47_03715	ENOG4105EEI	dihydropteroate synthase
E3H47_03750	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
E3H47_03770	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E3H47_03785	ENOG4105BZS	acriflavin resistance protein
E3H47_03790	ENOG4105CJW	magnesium transporter
E3H47_03800	ENOG4105D0M	Protease HtpX homolog
E3H47_03805	ENOG4105E4C	Lytic transglycosylase catalytic
E3H47_03810	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E3H47_03820	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
E3H47_03825	ENOG4108RRZ	Transcription elongation factor GreB
E3H47_03855	ENOG4107R8N	Glycosyl transferase, family 2
E3H47_03880	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3H47_03895	ENOG4105MRR	Transcriptional regulator (By similarity)
E3H47_03905	ENOG4108HW3	(ABC) transporter
E3H47_03930	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
E3H47_03935	ENOG4105DNH	Major Facilitator
E3H47_03950	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3H47_03960	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E3H47_03990	ENOG4105CHR	reductase
E3H47_04000	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E3H47_04035	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3H47_04115	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E3H47_04120	ENOG4105NX3	Membrane
E3H47_04135	ENOG4105BZU	Histidine kinase
E3H47_04140	ENOG4105EUJ	GTP cyclohydrolase i
E3H47_04155	ENOG4107QYG	anthranilate phosphoribosyltransferase
E3H47_04160	ENOG4105DDQ	anthranilate synthase
E3H47_04165	ENOG4105C5F	glutamine synthetase
E3H47_04180	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E3H47_04215	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3H47_04220	ENOG4107QNR	UPF0135 protein
E3H47_04225	ENOG4105C0H	protease
E3H47_04235	ENOG4105C6K	Malic enzyme
E3H47_04240	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E3H47_04245	ENOG4105SYT	Methylenetetrahydrofolate reductase
E3H47_04250	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E3H47_04255	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E3H47_04260	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E3H47_04265	ENOG4105CEP	NADH dehydrogenase
E3H47_04270	ENOG4105DZ1	carboxypeptidase
E3H47_04280	ENOG4105E9K	Isocitrate dehydrogenase
E3H47_04290	ENOG4108R99	pseudouridine synthase
E3H47_04305	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E3H47_04310	ENOG4108ETY	sodium dicarboxylate symporter
E3H47_04335	ENOG4105I7R	Adenylate cyclase
E3H47_04345	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E3H47_04365	ENOG4105D3G	Pseudouridine synthase
E3H47_04370	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E3H47_04400	ENOG4108JPW	Aminotransferase
E3H47_04405	ENOG4105DY8	decarboxylase
E3H47_04410	ENOG4105F7P	transcriptional regulator AsnC family
E3H47_04415	ENOG4107RA9	decarboxylase
E3H47_04420	ENOG4105C85	amino acid
E3H47_04430	ENOG4105C8U	phosphate abc transporter
E3H47_04440	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E3H47_04450	ENOG4105ERU	peptidase
E3H47_04465	ENOG4107QTF	adenylosuccinate lyase
E3H47_04470	ENOG41075W9	High frequency lysogenization protein HflD homolog
E3H47_04485	ENOG4108Z0R	Transferase
E3H47_04490	ENOG4105DZ1	carboxypeptidase
E3H47_04510	ENOG4108K5P	(LipO)protein
E3H47_04515	ENOG4105EJC	lysr family transcriptional regulator
E3H47_04520	ENOG4105C8Y	Acetylornithine aminotransferase
E3H47_04525	ENOG4105M2J	Glutaredoxin
E3H47_04530	ENOG4105DAN	ATP-dependent protease
E3H47_04545	ENOG4105DHU	Bile acid
E3H47_04565	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E3H47_04575	ENOG4105D22	carbon starvation protein
E3H47_04580	ENOG4105VCD	cytoplasmic protein
E3H47_04585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E3H47_04595	ENOG4105F8C	transglutaminase domain-containing protein
E3H47_04885	ENOG4105NVB	glycoside hydrolase, family 19
E3H47_04955	ENOG4105NVB	glycoside hydrolase, family 19
E3H47_05000	ENOG4105CHH	sulfate transporter
E3H47_05010	ENOG4105C7N	Xanthine uracil vitamin C permease
E3H47_05015	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E3H47_05025	ENOG4105C3Q	Glycosyl transferase, family 2
E3H47_05035	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E3H47_05045	ENOG4105CFH	Aspartokinase
E3H47_05055	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E3H47_05070	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E3H47_05085	ENOG4105CPC	Aldo Keto reductase
E3H47_05090	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E3H47_05095	ENOG4108UKZ	OsmC family
E3H47_05100	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3H47_05115	ENOG4105CXT	aspartate transcarbamylase
E3H47_05120	ENOG4105CD3	dihydroorotase
E3H47_05140	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E3H47_05145	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E3H47_05150	ENOG4108K3A	Glutathione S-transferase
E3H47_05170	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E3H47_05180	ENOG4105VEQ	Cold shock protein
E3H47_05185	ENOG4105C1J	atp-dependent rna helicase
E3H47_05195	ENOG41069NU	Nitroreductase
E3H47_05230	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E3H47_05250	ENOG4105ERG	peptidase m48, ste24p
E3H47_05255	ENOG4105KTH	gatB Yqey
E3H47_05260	ENOG4105VCC	30S ribosomal protein S21
E3H47_05270	ENOG4108HWY	Beta-lactamase
E3H47_05285	ENOG4105D9P	serine threonine protein kinase
E3H47_05320	ENOG4105C12	Phosphoribosylglycinamide synthetase
E3H47_05330	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E3H47_05385	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E3H47_05390	ENOG4105CDU	Replicative dna helicase
E3H47_05400	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E3H47_05415	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E3H47_05420	ENOG4105CCU	oxidase (Subunit III)
E3H47_05425	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E3H47_05430	ENOG4105E2S	oxidase) subunit II
E3H47_05455	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
E3H47_05475	ENOG4105DEN	Luciferase family
E3H47_05490	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E3H47_05495	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E3H47_05500	ENOG4108ZX5	transcriptional regulator
E3H47_05510	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_05525	ENOG4105D06	uba thif-type nad fad binding protein
E3H47_05535	ENOG4105KRF	dihydroneopterin aldolase
E3H47_05555	ENOG4105CFU	surface antigen
E3H47_05560	ENOG4105MA0	exported protein
E3H47_05575	ENOG4107QIJ	Aconitate hydratase 2
E3H47_05600	ENOG4105EW9	transcriptional regulator AsnC family
E3H47_05605	ENOG4105DHS	permease protein
E3H47_05610	ENOG4105CM4	permease protein
E3H47_05615	ENOG4108IPW	abc transporter atp-binding protein
E3H47_05625	ENOG4105F27	Major Facilitator
E3H47_05630	ENOG4105D6U	Sodium Glutamate Symporter
E3H47_05635	ENOG4105DZ2	Transcriptional regulator
E3H47_05640	ENOG4108VMM	UPF0756 membrane protein
E3H47_05645	ENOG4105I08	Pseudouridine synthase
E3H47_05655	ENOG4105DR9	pseudouridine synthase
E3H47_05660	ENOG4105K8N	protein family UPF0079, ATPase
E3H47_05665	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E3H47_05675	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E3H47_05680	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E3H47_05685	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E3H47_05690	ENOG4105EHM	Aminoglycoside phosphotransferase
E3H47_05695	ENOG4108S0S	Nucleotidyl transferase
E3H47_05705	ENOG4107QJE	Chromosome Partitioning Protein
E3H47_05710	ENOG4105FA0	parb-like partition protein
E3H47_05720	ENOG4105SG9	biopolymer transport protein, ExbD
E3H47_05725	ENOG4105BZ1	(ABC) transporter
E3H47_05730	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E3H47_05740	ENOG4107QRG	dna polymerase iii
E3H47_05750	ENOG4105F8V	Hydrolase, tatD family
E3H47_05760	ENOG4108VAU	general secretion pathway protein G
E3H47_05770	ENOG4108WWZ	General secretion pathway protein J
E3H47_05795	ENOG4108Z6B	deaminase
E3H47_05810	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E3H47_05815	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E3H47_05835	ENOG4108IMY	Transcriptional regulator
E3H47_05845	ENOG4105DWU	Membrane
E3H47_05850	ENOG4107RN6	Monooxygenase
E3H47_05860	ENOG4105D6Z	AFG1 family ATPase
E3H47_05870	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E3H47_05875	ENOG4105EVZ	LysR family transcriptional regulator
E3H47_05885	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E3H47_05890	ENOG4107RUY	(E1 component), alpha subunit
E3H47_05895	ENOG4105CPP	Dehydrogenase, E1 component
E3H47_05900	ENOG4105C7S	Dehydrogenase
E3H47_05915	ENOG4105CHR	reductase
E3H47_05945	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E3H47_05950	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E3H47_05955	ENOG4105CC0	LysR family Transcriptional regulator
E3H47_05965	ENOG4105ETT	transcriptional Regulator, LysR family
E3H47_05970	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_05985	ENOG4105PV3	Inner membrane protein yqiJ
E3H47_06005	ENOG4105HDD	phospholipase
E3H47_06010	ENOG4105CZN	Potassium uptake protein
E3H47_06020	ENOG4105C7B	Threonine dehydratase
E3H47_06025	ENOG4105E66	phosphoriboisomerase A
E3H47_06035	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E3H47_06045	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E3H47_06050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E3H47_06075	ENOG4105CR4	methylisocitrate lyase
E3H47_06080	ENOG4105BZN	citrate synthase
E3H47_06090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E3H47_06095	ENOG4105CUX	Signal transduction histidine kinase
E3H47_06110	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E3H47_06115	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E3H47_06120	ENOG4105KNE	Phosphatidate cytidylyltransferase
E3H47_06130	ENOG4105DZP	Membrane-associated zinc metalloprotease
E3H47_06135	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E3H47_06155	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3H47_06170	ENOG4105Y3E	Modulates RecA activity (By similarity)
E3H47_06175	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E3H47_06180	ENOG4105VEJ	Heat shock protein
E3H47_06185	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E3H47_06190	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E3H47_06200	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E3H47_06205	ENOG4105K4T	epimerase
E3H47_06210	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E3H47_06225	ENOG4108JA2	transcriptioN-repair coupling factor
E3H47_06235	ENOG4105F8J	Adenylate Guanylate cyclase
E3H47_06240	ENOG4108ZIT	Ferredoxin, 2FE-2S
E3H47_06255	ENOG4108Z4V	iron-sulfur cluster assembly
E3H47_06260	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E3H47_06270	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E3H47_06285	ENOG4105K70	DNA-binding protein
E3H47_06290	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E3H47_06300	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_06305	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_06325	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E3H47_06330	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E3H47_06335	ENOG4105CEV	competence damage-inducible protein
E3H47_06365	ENOG4105VEQ	Cold shock protein
E3H47_06370	ENOG4107VMU	Membrane
E3H47_06375	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
E3H47_06385	ENOG4105NIV	Esterase
E3H47_06395	ENOG4107ZQV	short-chain dehydrogenase reductase
E3H47_06430	ENOG4105BZU	Histidine kinase
E3H47_06460	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E3H47_06465	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E3H47_06470	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E3H47_06490	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
E3H47_06495	ENOG4105CMR	udp-glucose 4-epimerase
E3H47_06555	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E3H47_06560	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E3H47_06575	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
E3H47_06615	ENOG4105EW9	transcriptional regulator AsnC family
E3H47_06620	ENOG4105CK7	Sodium proline symporter
E3H47_06625	ENOG4108IJ0	Aspartate ammonia-lyase
E3H47_06635	ENOG4107RZC	phospholipase d
E3H47_06645	ENOG4105CGF	Aromatic amino acid aminotransferase
E3H47_06650	ENOG4105C85	amino acid
E3H47_06665	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3H47_06670	ENOG4105CZM	Major Facilitator
E3H47_06675	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E3H47_06680	ENOG4108ZX5	transcriptional regulator
E3H47_06690	ENOG4105BZ1	(ABC) transporter
E3H47_06695	ENOG410620I	Diguanylate cyclase
E3H47_06710	ENOG4105BZU	Histidine kinase
E3H47_06715	ENOG4108J1Q	
E3H47_06730	ENOG4105CUY	Mechanosensitive ion channel
E3H47_06735	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
E3H47_06755	ENOG41080HT	Transcriptional regulator, arsr family
E3H47_06785	ENOG4105MP9	class II Aldolase
E3H47_06790	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
E3H47_06795	ENOG4108UKI	Enoyl-CoA hydratase
E3H47_06800	ENOG4105EA8	2-Nitropropane dioxygenase
E3H47_06815	ENOG4105FFC	UPF0187 protein
E3H47_06820	ENOG4105CEB	Aspartate aminotransferase
E3H47_06860	ENOG4105CC0	LysR family Transcriptional regulator
E3H47_06905	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E3H47_06910	ENOG4105C4R	Atp-dependent dna helicase
E3H47_06945	ENOG4105CSH	Transporter
E3H47_06950	ENOG4105E39	Enoyl-CoA hydratase
E3H47_06955	ENOG4105E39	Enoyl-CoA hydratase
E3H47_06960	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_06970	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E3H47_06975	ENOG4105C26	Dehydrogenase
E3H47_06980	ENOG4107YNJ	LysR family Transcriptional regulator
E3H47_06985	ENOG4108Z0R	Transferase
E3H47_06990	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
E3H47_06995	ENOG4105DZS	Phenylacetate-CoA ligase
E3H47_07000	ENOG4108UKI	Enoyl-CoA hydratase
E3H47_07005	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E3H47_07010	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
E3H47_07015	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
E3H47_07020	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
E3H47_07025	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
E3H47_07030	ENOG4105DXM	phenylacetic acid degradation protein
E3H47_07040	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E3H47_07045	ENOG4105E0C	molybdate abc transporter
E3H47_07050	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E3H47_07055	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E3H47_07060	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3H47_07065	ENOG4108ZAF	Molybdopterin
E3H47_07075	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E3H47_07095	ENOG4108IFG	nitrite reductase, (NAD(P)H)
E3H47_07100	ENOG4107QZF	nitrite reductase NADPH large subunit
E3H47_07105	ENOG4107RNU	major facilitator superfamily MFS_1
E3H47_07125	ENOG4105TW1	Carbohydrate-selective porin OprB
E3H47_07130	ENOG4105DZG	Dehydrogenase
E3H47_07135	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E3H47_07170	ENOG4107QNJ	CoA-transferase subunit B
E3H47_07180	ENOG4107RGD	Major Facilitator superfamily
E3H47_07185	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_07190	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_07200	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E3H47_07205	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_07210	ENOG4107RGD	Major Facilitator superfamily
E3H47_07215	ENOG4105EQ0	Major Facilitator superfamily
E3H47_07225	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E3H47_07230	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_07235	ENOG4107RGD	Major Facilitator superfamily
E3H47_07240	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E3H47_07265	ENOG4105CMU	LysR family (Transcriptional regulator
E3H47_07270	ENOG4105VAW	lrga family
E3H47_07275	ENOG41067MG	lrgb family
E3H47_07285	ENOG4105CVJ	phosphoglycerate mutase
E3H47_07290	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
E3H47_07295	ENOG4108YZT	Adenosylcobinamide kinase
E3H47_07335	ENOG4108Z66	YbaK ebsC protein
E3H47_07375	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E3H47_07380	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E3H47_07405	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E3H47_07440	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3H47_07445	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E3H47_07475	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E3H47_07485	ENOG4105C28	cystathionine
E3H47_07500	ENOG4105D6J	arsenicaL-resistance protein
E3H47_07505	ENOG41082YX	Transcriptional regulator, arsr family
E3H47_07550	ENOG4105VEQ	Cold shock protein
E3H47_07555	ENOG4105D1S	lipid A biosynthesis
E3H47_07570	ENOG4105K59	histidine triad (HIT) protein
E3H47_07595	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E3H47_07615	ENOG4107TSN	permease
E3H47_07620	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E3H47_07650	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E3H47_07655	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E3H47_07690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3H47_07705	ENOG4108KB2	LysR family Transcriptional regulator
E3H47_07710	ENOG4105DTQ	mandelate racemase muconate lactonizing
E3H47_07715	ENOG4105NN7	muconolactone delta-isomerase
E3H47_07725	ENOG4105FUY	alpha subunit
E3H47_07730	ENOG4108UKV	benzoate 1,2-dioxygenase
E3H47_07735	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
E3H47_07740	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
E3H47_07750	ENOG4107QP7	CoA-transferase subunit A
E3H47_07755	ENOG4107QNJ	CoA-transferase subunit B
E3H47_07760	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_07765	ENOG4105F2Z	3-oxoadipate enol-lactonase
E3H47_07780	ENOG4105CSH	Transporter
E3H47_07785	ENOG4105EV9	Alpha Beta Hydrolase
E3H47_07795	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E3H47_07815	ENOG4105VT2	5-hydroxyisourate hydrolase
E3H47_07820	ENOG4105CHB	tonB-dependent Receptor
E3H47_07835	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E3H47_07840	ENOG4105C2W	permease
E3H47_07845	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E3H47_07850	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
E3H47_07855	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
E3H47_07860	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
E3H47_07870	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
E3H47_07885	ENOG4105CX6	glutaminyL-tRNA synthetase
E3H47_07895	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E3H47_07900	ENOG4108RCM	Nitroreductase
E3H47_07905	ENOG4108TZV	Membrane
E3H47_07910	ENOG4105D2N	Aldolase
E3H47_07930	ENOG4108UHJ	MAF-like protein
E3H47_07935	ENOG4105EZE	Cupin 4 family protein
E3H47_07940	ENOG4105CBC	glutamate synthase
E3H47_07965	ENOG4105KJF	protein tyrosine phosphatase
E3H47_07970	ENOG4105C0A	alcohol dehydrogenase
E3H47_07980	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E3H47_07985	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E3H47_08000	ENOG4105CHR	reductase
E3H47_08005	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_08015	ENOG4105HEI	LysR family (Transcriptional regulator
E3H47_08020	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E3H47_08025	ENOG4108NIW	Leucine export protein LeuE
E3H47_08030	ENOG4105DKK	Benzoate
E3H47_08035	ENOG410814C	multidrug resistance protein
E3H47_08050	ENOG41081QV	Universal stress protein
E3H47_08055	ENOG4105CD8	aminopeptidase N
E3H47_08075	ENOG4107QUV	Domain protein
E3H47_08080	ENOG4105C0A	alcohol dehydrogenase
E3H47_08090	ENOG4107RR1	TRANSCRIPTIONal
E3H47_08100	ENOG4105CUB	amino acid
E3H47_08105	ENOG4105CPD	ethanolamine ammonia-lyase
E3H47_08110	ENOG4107FQ9	ethanolamine ammonia-lyase
E3H47_08115	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E3H47_08120	ENOG4108YYC	ycei family
E3H47_08130	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E3H47_08165	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E3H47_08170	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E3H47_08230	ENOG4105D01	(LipO)protein
E3H47_08235	ENOG4105D01	(LipO)protein
E3H47_08240	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3H47_08245	ENOG4108UMI	ABC transporter, permease
E3H47_08250	ENOG4105C3G	gtp-binding protein
E3H47_08265	ENOG4108UMN	azlc family
E3H47_08270	ENOG4105ZED	uncharacterized protein ygaH
E3H47_08280	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E3H47_08285	ENOG4105CHM	Aminotransferase
E3H47_08290	ENOG4108V06	Glutathione peroxidase
E3H47_08295	ENOG4105E0X	reductase
E3H47_08300	ENOG4105CHM	Aminotransferase
E3H47_08310	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E3H47_08315	ENOG4108UMI	ABC transporter, permease
E3H47_08320	ENOG4105C0B	DNA polymerase III (alpha subunit)
E3H47_08350	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E3H47_08365	ENOG4105C7K	acetolactate synthase
E3H47_08380	ENOG4105CHR	reductase
E3H47_08385	ENOG4108MXF	Alpha Beta Hydrolase
E3H47_08395	ENOG4105DJB	Major Facilitator Superfamily
E3H47_08400	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
E3H47_08410	ENOG4105CHR	reductase
E3H47_08430	ENOG4107HP6	Transcriptional regulator
E3H47_08435	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
E3H47_08440	ENOG4108YS2	small subunit
E3H47_08445	ENOG4105F57	Anthranilate dioxygenase reductase
E3H47_08455	ENOG4105D2S	major facilitator superfamily
E3H47_08460	ENOG4105CF7	AraC family transcriptional regulator
E3H47_08470	ENOG4108K70	Transcriptional regulator
E3H47_08485	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3H47_08490	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
E3H47_08505	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
E3H47_08510	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
E3H47_08525	ENOG4105F52	Transcriptional regulator
E3H47_08550	ENOG4105M6W	Crispr-associated protein, Csy3 family
E3H47_08595	ENOG4105BZU	Histidine kinase
E3H47_08600	ENOG4105N14	lysine exporter protein LysE YggA
E3H47_08605	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E3H47_08610	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E3H47_08645	ENOG4105ETT	transcriptional Regulator, LysR family
E3H47_08655	ENOG4105DXI	Major Facilitator superfamily
E3H47_08665	ENOG4105CEY	Amp-dependent synthetase and ligase
E3H47_08670	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_08675	ENOG4108IPT	Naphthoate synthase
E3H47_08685	ENOG41067TZ	transcriptional regulator, MarR family
E3H47_08725	ENOG4105DJU	Siderophore biosynthesis protein
E3H47_08730	ENOG4105DUU	IucA IucC family protein
E3H47_08770	ENOG4108Z4U	Ferredoxin
E3H47_08780	ENOG4107ZBN	O-methyltransferase
E3H47_08795	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E3H47_08810	ENOG4105DFG	type I secretion outer membrane protein
E3H47_08815	ENOG4108IUZ	ABC transporter
E3H47_08820	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E3H47_08830	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
E3H47_08835	ENOG4105C2X	Arabinose 5-phosphate isomerase
E3H47_08850	ENOG4105EWC	Purine nucleoside phosphorylase
E3H47_08860	ENOG4105CI2	imidazolone-5-propionate hydrolase
E3H47_08875	ENOG4105BZU	Histidine kinase
E3H47_08895	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E3H47_08915	ENOG4105CQM	Urea amidohydrolase subunit alpha
E3H47_08930	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
E3H47_08940	ENOG4105C26	Dehydrogenase
E3H47_08950	ENOG4105C26	Dehydrogenase
E3H47_08970	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E3H47_08975	ENOG4105D82	Glutamate dehydrogenase
E3H47_08980	ENOG4105C26	Dehydrogenase
E3H47_08985	ENOG4108JPW	Aminotransferase
E3H47_08990	ENOG4105C26	Dehydrogenase
E3H47_09010	ENOG4105CUB	amino acid
E3H47_09015	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
E3H47_09035	ENOG4105CQ7	ATP-dependent helicase
E3H47_09040	ENOG4105D3R	alkyl hydroperoxide reductase
E3H47_09060	ENOG4108JU3	Alkyl hydroperoxide reductase
E3H47_09095	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E3H47_09100	ENOG4105CQC	Prephenate dehydratase
E3H47_09105	ENOG4105CEY	Amp-dependent synthetase and ligase
E3H47_09110	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_09115	ENOG4105CK2	sodium dicarboxylate symporter
E3H47_09130	ENOG4105VUT	cytoplasmic protein
E3H47_09135	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E3H47_09140	ENOG4105BZ4	penicillin-binding protein
E3H47_09150	ENOG4105M6F	mutator MutT protein
E3H47_09160	ENOG4105DHQ	Histidine kinase
E3H47_09165	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3H47_09170	ENOG4105WXI	Bacterial OB fold (BOF) protein
E3H47_09175	ENOG4107QHF	type ii secretion system protein e
E3H47_09180	ENOG410620I	Diguanylate cyclase
E3H47_09185	ENOG4108R96	Methyltransferase, YaeB family
E3H47_09190	ENOG4105DP0	ferredoxin-NADP reductase
E3H47_09195	ENOG4105CFP	Peptidase U32
E3H47_09200	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E3H47_09205	ENOG4108JU3	Alkyl hydroperoxide reductase
E3H47_09225	ENOG4105NXH	GreA GreB family elongation factor
E3H47_09265	ENOG4105DA5	(ABC) transporter
E3H47_09270	ENOG4105E3A	(ABC) transporter
E3H47_09285	ENOG4105CNI	cell division protein FtsW
E3H47_09290	ENOG4105CVE	Lytic murein transglycosylase
E3H47_09310	ENOG4105CE9	30S ribosomal protein S2
E3H47_09315	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E3H47_09330	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
E3H47_09335	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E3H47_09340	ENOG4107QPN	acyl-Coa dehydrogenase
E3H47_09350	ENOG41066VF	YeeE YedE family protein
E3H47_09375	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E3H47_09385	ENOG4105BZU	Histidine kinase
E3H47_09390	ENOG4105EE5	Membrane protein terC
E3H47_09400	ENOG4107SCA	Formamidase (EC 3.5.1.49)
E3H47_09405	ENOG4107QS8	(LipO)protein
E3H47_09415	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E3H47_09440	ENOG4105DTR	rard protein
E3H47_09445	ENOG4105QNF	Outer membrane lipoprotein
E3H47_09450	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E3H47_09460	ENOG4108KHP	Diguanylate cyclase
E3H47_09465	ENOG4105CHM	Aminotransferase
E3H47_09470	ENOG4107YPT	transcriptional regulator
E3H47_09490	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E3H47_09495	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E3H47_09500	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E3H47_09510	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E3H47_09515	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E3H47_09525	ENOG4105C3F	Signal peptidase i
E3H47_09540	ENOG4105C0H	protease
E3H47_09545	ENOG4108IYU	L-aspartate oxidase
E3H47_09555	ENOG4105HHA	aminodeoxychorismate lyase
E3H47_09560	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
E3H47_09565	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E3H47_09575	ENOG4108I5D	sulfate abc transporter
E3H47_09580	ENOG4105ECW	sulfate abc transporter
E3H47_09585	ENOG4108IJ6	ABC transporter
E3H47_09590	ENOG4107R11	Transcriptional regulator
E3H47_09605	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E3H47_09610	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E3H47_09620	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E3H47_09630	ENOG41060WC	Enoyl-CoA hydratase
E3H47_09640	ENOG4105EGD	dinuclear metal center protein, YbgI family
E3H47_09650	ENOG4108ETH	Formylglycinamide ribotide synthetase
E3H47_09665	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E3H47_09670	ENOG4105F95	Monooxygenase
E3H47_09685	ENOG4107YD3	Thioesterase
E3H47_09690	ENOG4105E02	MotA TolQ exbB proton channel
E3H47_09695	ENOG4105M8F	Biopolymer transport protein exbD tolR
E3H47_09705	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E3H47_09710	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E3H47_09765	ENOG4105C02	permease
E3H47_09770	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E3H47_09775	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E3H47_09795	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
E3H47_09800	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E3H47_09820	ENOG4108UPT	UPF0178 protein
E3H47_09840	ENOG4107KET	secretion protein, HlyD family
E3H47_09855	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3H47_09860	ENOG4105C10	Electron transfer flavoprotein
E3H47_09865	ENOG4105BZJ	Electron transfer flavoprotein
E3H47_09870	ENOG4108NIW	Leucine export protein LeuE
E3H47_09875	ENOG4105EW9	transcriptional regulator AsnC family
E3H47_09885	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E3H47_09890	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E3H47_09895	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E3H47_09905	ENOG4105C85	amino acid
E3H47_09910	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E3H47_09920	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
E3H47_09930	ENOG4105CFQ	glutamine synthetase
E3H47_09935	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
E3H47_09945	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E3H47_09950	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3H47_09955	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E3H47_09965	ENOG4108IQI	permease
E3H47_09975	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
E3H47_09980	ENOG4105C26	Dehydrogenase
E3H47_09985	ENOG4105F4X	arginine
E3H47_09990	ENOG4105C8Y	Acetylornithine aminotransferase
E3H47_09995	ENOG4105D82	Glutamate dehydrogenase
E3H47_10010	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3H47_10015	ENOG4105CXG	d-lactate dehydrogenase
E3H47_10025	ENOG41073TP	transcriptional regulator
E3H47_10030	ENOG4105DAA	L-lactate
E3H47_10045	ENOG4105EKE	dihydroorotase
E3H47_10050	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E3H47_10065	ENOG4108IQI	permease
E3H47_10085	ENOG4108JQ5	ABC transporter
E3H47_10090	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E3H47_10095	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E3H47_10105	ENOG4105E9H	Lytic Murein transglycosylase
E3H47_10105	ENOG4105E9H	Lytic Murein transglycosylase
E3H47_10110	ENOG4107RZZ	dna polymerase iii epsilon subunit
E3H47_10120	ENOG4105E09	nadh pyrophosphatase
E3H47_10130	ENOG4105W4M	Transport-associated protein
E3H47_10140	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E3H47_10145	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E3H47_10155	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E3H47_10160	ENOG4105D0A	hydroxylase
E3H47_10165	ENOG4107RAQ	aminopeptidase
E3H47_10190	ENOG4108YXU	transcriptional regulator AsnC family
E3H47_10210	ENOG4105EEF	Alkane 1-monooxygenase
E3H47_10215	ENOG4105EZV	Transcriptional regulator
E3H47_10230	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E3H47_10240	ENOG4107VAM	peptidase, m28
E3H47_10245	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E3H47_10250	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E3H47_10260	ENOG4105D82	Glutamate dehydrogenase
E3H47_10265	ENOG4108R3D	Electron transport complex
E3H47_10270	ENOG4105CSM	endonuclease III
E3H47_10295	ENOG4105CJN	penicillin-binding protein
E3H47_10300	ENOG4106H78	methyltransferase
E3H47_10315	ENOG4105CHR	reductase
E3H47_10335	ENOG4107RET	Isocitrate lyase
E3H47_10345	ENOG4105C37	(CBS) domain
E3H47_10360	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
E3H47_10365	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E3H47_10370	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E3H47_10375	ENOG4108MRJ	
E3H47_10390	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E3H47_10395	ENOG4105VCQ	rubredoxin
E3H47_10400	ENOG4107QZF	nitrite reductase NADPH large subunit
E3H47_10410	ENOG4105C5Q	Transcriptional regulator
E3H47_10425	ENOG4107U91	Rhomboid family
E3H47_10430	ENOG4105CV6	ABC transporter, permease
E3H47_10435	ENOG4108I0Y	(ABC) transporter
E3H47_10440	ENOG4108UJV	acyl-CoA thioesterase i
E3H47_10445	ENOG4108V9Q	carbonic anhydrase
E3H47_10460	ENOG4107RNH	Outer membrane receptor FepA
E3H47_10475	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
E3H47_10480	ENOG4105E6M	Sulphatase-modifying factor protein
E3H47_10490	ENOG4105CJ3	phosphate transporter
E3H47_10495	ENOG4105C3R	Methionine synthase
E3H47_10510	ENOG4105CSH	Transporter
E3H47_10525	ENOG4105CSH	Transporter
E3H47_10555	ENOG4105KT7	mgtC SapB transporter
E3H47_10560	ENOG4108VWS	Yaeq family
E3H47_10565	ENOG4105CKI	cobalamin synthesis protein
E3H47_10590	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
E3H47_10595	ENOG4105C94	Transporter
E3H47_10605	ENOG4105C2I	pirin domain protein
E3H47_10615	ENOG4105E3B	Multicopper oxidase
E3H47_10630	ENOG4108RXX	maleylacetoacetate isomerase
E3H47_10650	ENOG4105CRW	Short chain fatty acid transporter
E3H47_10655	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_10665	ENOG41081QV	Universal stress protein
E3H47_10710	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E3H47_10715	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E3H47_10720	ENOG4105CW7	secretion protein, HlyD family
E3H47_10730	ENOG4108VUY	thioesterase Superfamily protein
E3H47_10735	ENOG4105D52	delta-aminolevulinic acid dehydratase
E3H47_10740	ENOG4108DN8	FAD dependent oxidoreductase
E3H47_10745	ENOG4105ECP	epimerase
E3H47_10755	ENOG4107RH8	nuclease SbcCD subunit D
E3H47_10760	ENOG4105EYH	Exonuclease
E3H47_10765	ENOG4105DFA	alanine racemase domain protein
E3H47_10770	ENOG4105CZX	twitching motility protein
E3H47_10775	ENOG4105CZX	twitching motility protein
E3H47_10780	ENOG41090R7	Ferric uptake
E3H47_10805	ENOG4105E7A	Glutamine amidotransferase
E3H47_10815	ENOG4107QKV	phosphomannomutase
E3H47_10820	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E3H47_10825	ENOG4105C4R	Atp-dependent dna helicase
E3H47_10830	ENOG4108ZG0	Ompa motb domain protein
E3H47_10835	ENOG4106HNH	Acyl-transferase
E3H47_10850	ENOG4107QMS	site-determining protein
E3H47_10865	ENOG4105CNU	cell division protein FtsK
E3H47_10870	ENOG4105C3M	thioredoxin reductase
E3H47_10875	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E3H47_10885	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E3H47_10925	ENOG4108YXA	Membrane
E3H47_10935	ENOG4105DWF	phosphomethylpyrimidine kinase
E3H47_10940	ENOG4109066	lysm domain bon superfamily protein
E3H47_10950	ENOG4105CHR	reductase
E3H47_10955	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E3H47_10965	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E3H47_10970	ENOG4108BPE	-transporting atpase
E3H47_10975	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E3H47_10985	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E3H47_10990	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E3H47_10995	ENOG4105FE9	pseudouridine synthase
E3H47_11005	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E3H47_11010	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E3H47_11020	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E3H47_11025	ENOG4108UWD	Iron-storage protein
E3H47_11030	ENOG4108K4C	ec 3.1.3.12
E3H47_11035	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E3H47_11040	ENOG4106UW1	Major Facilitator superfamily
E3H47_11045	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E3H47_11055	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E3H47_11065	ENOG4105HF0	Membrane
E3H47_11080	ENOG4105MJ9	esterase
E3H47_11085	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E3H47_11095	ENOG4108D32	Methyltransferase
E3H47_11100	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
E3H47_11130	ENOG4105D3G	Pseudouridine synthase
E3H47_11160	ENOG4108I0Z	Aconitate hydratase
E3H47_11165	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E3H47_11175	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3H47_11180	ENOG4108VX5	3-methyladenine DNA glycosylase
E3H47_11190	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E3H47_11195	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E3H47_11205	ENOG4105C2W	permease
E3H47_11215	ENOG4108IQI	permease
E3H47_11220	ENOG4108WHA	ompa motb domain protein
E3H47_11230	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_11270	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
E3H47_11275	ENOG4105WD1	Membrane
E3H47_11285	ENOG4106BSU	Entericidin B
E3H47_11290	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
E3H47_11300	ENOG4105CBS	Chea signal transduction histidine kinase
E3H47_11305	ENOG4105C8Q	Methyl-accepting chemotaxis
E3H47_11310	ENOG4108ZGA	chew protein
E3H47_11315	ENOG4105M3Z	response regulator
E3H47_11320	ENOG4108UNF	response regulator
E3H47_11340	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
E3H47_11375	ENOG4105D1F	ATP-binding protein
E3H47_11380	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E3H47_11415	ENOG4105CBX	hi0933 family
E3H47_11440	ENOG4105DP0	ferredoxin-NADP reductase
E3H47_11445	ENOG4105DUM	transcriptional regulator, lysR family
E3H47_11460	ENOG4105C8S	subunit m
E3H47_11465	ENOG4105D65	subunit l
E3H47_11470	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3H47_11475	ENOG4107UFS	subunit j
E3H47_11480	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E3H47_11490	ENOG4108IEH	NADH dehydrogenase subunit g
E3H47_11495	ENOG4107QIZ	NADH dehydrogenase
E3H47_11500	ENOG4105GKE	subunit e
E3H47_11515	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E3H47_11530	ENOG4105JJR	Histidine kinase
E3H47_11535	ENOG4107EXC	regulatoR
E3H47_11540	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3H47_11555	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E3H47_11560	ENOG4108KB2	LysR family Transcriptional regulator
E3H47_11565	ENOG4105CNM	Receptor
E3H47_11580	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E3H47_11590	ENOG4105DJV	ribulose-phosphate 3-epimerase
E3H47_11615	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E3H47_11620	ENOG41072GX	Peptidase M22 Glycoprotease
E3H47_11625	ENOG4108Z0R	Transferase
E3H47_11630	ENOG4105P8F	nudix hydrolase
E3H47_11670	ENOG4105CRQ	synthase (Component I)
E3H47_11680	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E3H47_11685	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E3H47_11690	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E3H47_11760	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E3H47_11775	ENOG4105D3R	alkyl hydroperoxide reductase
E3H47_11790	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E3H47_11795	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E3H47_11810	ENOG4108ZX5	transcriptional regulator
E3H47_11830	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E3H47_11840	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E3H47_11845	ENOG4108WBT	adenosyltransferase
E3H47_11865	ENOG4105CNG	UPF0061 protein
E3H47_11870	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E3H47_11875	ENOG4105EB3	Histidine kinase
E3H47_11885	ENOG4105CSU	acyl-Coa dehydrogenase
E3H47_11890	ENOG4105CSU	acyl-Coa dehydrogenase
E3H47_11895	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E3H47_11900	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E3H47_11910	ENOG4105VW4	glutaredoxin 3
E3H47_11915	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
E3H47_11920	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E3H47_11925	ENOG4105W5Q	DNA repair protein (RadC
E3H47_11930	ENOG4105FFC	UPF0187 protein
E3H47_11945	ENOG4105K9H	YciI-like protein
E3H47_11965	ENOG4108VPT	UPF0234 protein
E3H47_11975	ENOG4105NAU	thioesterase Superfamily protein
E3H47_11985	ENOG4107QPB	Beta-lactamase domain protein
E3H47_12040	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E3H47_12045	ENOG4105D6S	protein involved in catabolism of external DNA
E3H47_12075	ENOG4105E4C	Lytic transglycosylase catalytic
E3H47_12080	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E3H47_12085	ENOG4105C9A	Phoh family
E3H47_12090	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E3H47_12120	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E3H47_12125	ENOG4107S2Z	UPF0761 membrane protein
E3H47_12130	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E3H47_12165	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E3H47_12170	ENOG4105DGW	oligopeptidase A
E3H47_12175	ENOG4105VKU	nucleicacid-binding protein
E3H47_12210	ENOG4105C1G	acyl-Coa dehydrogenase
E3H47_12215	ENOG4105CT3	Monooxygenase
E3H47_12220	ENOG4108ZT0	50S ribosomal protein l17
E3H47_12225	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E3H47_12230	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E3H47_12235	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E3H47_12245	ENOG41067V7	50S ribosomal protein L36
E3H47_12250	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E3H47_12265	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E3H47_12280	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E3H47_12295	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E3H47_12300	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E3H47_12305	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E3H47_12320	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E3H47_12330	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E3H47_12340	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E3H47_12345	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E3H47_12350	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E3H47_12360	ENOG41089BK	Glutamine amido-transferase
E3H47_12365	ENOG4105C28	cystathionine
E3H47_12370	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E3H47_12375	ENOG4105KPV	Transcriptional regulator
E3H47_12385	ENOG4105CK2	sodium dicarboxylate symporter
E3H47_12390	ENOG4105C29	acyl-CoA thioesterase
E3H47_12395	ENOG4105E55	glycerol-3-phosphate acyltransferase
E3H47_12405	ENOG4105CB5	ATP-dependent DNA helicase recG
E3H47_12410	ENOG4105MJ2	Competence protein
E3H47_12420	ENOG4108URH	decarboxylase
E3H47_12425	ENOG4107QUT	magnesium and cobalt transport protein CorA
E3H47_12435	ENOG4105E3I	toluene tolerance
E3H47_12440	ENOG4107PE3	Mammalian cell entry related domain protein
E3H47_12445	ENOG4105CY3	ABC transporter, permease
E3H47_12450	ENOG4105DHJ	ABC, transporter
E3H47_12455	ENOG4105C1J	atp-dependent rna helicase
E3H47_12460	ENOG4105ECY	inositol monophosphatase
E3H47_12465	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E3H47_12475	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E3H47_12495	ENOG4105CSU	acyl-Coa dehydrogenase
E3H47_12505	ENOG41067S9	phage shock protein C, PspC
E3H47_12520	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
E3H47_12525	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E3H47_12545	ENOG4105C5I	Dehydrogenase
E3H47_12585	ENOG4105IPI	Membrane
E3H47_12590	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E3H47_12595	ENOG4107QF7	multi-drug
E3H47_12605	ENOG4105CQB	FAD linked oxidase domain protein
E3H47_12610	ENOG4108JQ1	Dehydrogenase
E3H47_12615	ENOG4107AQZ	Membrane
E3H47_12620	ENOG4107AQZ	Membrane
E3H47_12635	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E3H47_12640	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
E3H47_12645	ENOG4107IFA	Lipase (EC 3.1.1.3)
E3H47_12650	ENOG4107IFA	Lipase (EC 3.1.1.3)
E3H47_12655	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E3H47_12665	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E3H47_12670	ENOG4105K5M	30s ribosomal protein S16
E3H47_12705	ENOG4105X0D	Fimbrial protein
E3H47_12715	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E3H47_12720	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E3H47_12725	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E3H47_12730	ENOG4105KME	endoribonuclease L-psp
E3H47_12735	ENOG4105W53	bacterioferritin-associated ferredoxin
E3H47_12740	ENOG4108UQY	Iron-storage protein
E3H47_12760	ENOG4105CG5	Glycosyl transferase (Group 1
E3H47_12775	ENOG4105CKK	Glycosyl transferase, family 2
E3H47_12795	ENOG4105HA9	of methanol dehydrogenase type
E3H47_12800	ENOG4108V0P	LemA family
E3H47_12810	ENOG4105BZ8	glutamate synthase
E3H47_12815	ENOG4105CBC	glutamate synthase
E3H47_12835	ENOG4105E4G	Type IV pilus
E3H47_12860	ENOG4108JQC	penicillin-binding protein 1A
E3H47_12865	ENOG4105DHI	Methyltransferase
E3H47_12875	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E3H47_12880	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E3H47_12885	ENOG4105CJN	penicillin-binding protein
E3H47_12895	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E3H47_12900	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E3H47_12910	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E3H47_12935	ENOG4105C5H	ABC transporter
E3H47_12945	ENOG4105PDP	Short chain dehydrogenase
E3H47_12960	ENOG4105BZM	domain protein
E3H47_12965	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E3H47_12970	ENOG4105E0F	Histidine kinase
E3H47_12975	ENOG4105CYC	Transferase
E3H47_13005	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E3H47_13020	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E3H47_13025	ENOG410631K	Membrane
E3H47_13040	ENOG4105CUV	Homoserine Kinase
E3H47_13045	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E3H47_13100	ENOG4105CVN	desaturase
E3H47_13110	ENOG4105CEV	competence damage-inducible protein
E3H47_13130	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E3H47_13140	ENOG4105ESI	atpase involved in dna repair
E3H47_13175	ENOG4108UUM	single-stranded DNA-binding protein
E3H47_13180	ENOG4107RDB	Major Facilitator
E3H47_13195	ENOG4105DWF	phosphomethylpyrimidine kinase
E3H47_13200	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E3H47_13215	ENOG4105C94	Transporter
E3H47_13235	ENOG41062QD	Membrane
E3H47_13240	ENOG4105BZU	Histidine kinase
E3H47_13255	ENOG4108UZX	fmn reductase
E3H47_13265	ENOG4107T8P	acyl-Coa dehydrogenase
E3H47_13270	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E3H47_13275	ENOG4105KAF	membrAne
E3H47_13280	ENOG4105D64	Mechanosensitive ion channel
E3H47_13290	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E3H47_13295	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E3H47_13310	ENOG4105DQR	SNARE associated Golgi
E3H47_13325	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E3H47_13340	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E3H47_13360	ENOG4107QSN	dihydrolipoamide acetyltransferase
E3H47_13365	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E3H47_13385	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E3H47_13390	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E3H47_13395	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E3H47_13405	ENOG4105DFU	Cell wall formation (By similarity)
E3H47_13415	ENOG4105CZQ	inner membrane transport protein YdhC
E3H47_13425	ENOG4105D7Z	glutathione synthase
E3H47_13435	ENOG4105CGK	Exodeoxyribonuclease III
E3H47_13475	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E3H47_13480	ENOG4105IPS	esterase
E3H47_13495	ENOG4105D9M	gamma-glutamylcysteine synthetase
E3H47_13515	ENOG4105CHM	Aminotransferase
E3H47_13520	ENOG4107QJQ	Mate efflux family protein
E3H47_13535	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E3H47_13540	ENOG4105BZU	Histidine kinase
E3H47_13545	ENOG4105DJ4	phosphatidylserine decarboxylase
E3H47_13550	ENOG4105KHC	sulfurtransferase
E3H47_13565	ENOG4105CH6	catalase
E3H47_13585	ENOG4105EAC	phosphoserine phosphatase
E3H47_13595	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E3H47_13600	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E3H47_13605	ENOG4107YIM	Involved in the transcription termination process (By similarity)
E3H47_13610	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E3H47_13615	ENOG4108ZAI	phosphatidylglycerophosphatase a
E3H47_13625	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E3H47_13630	ENOG4105T38	integral membrane protein
E3H47_13640	ENOG4105C09	Bile acid
E3H47_13645	ENOG4108RWI	nicotinamidase
E3H47_13650	ENOG4108SC4	)-transporter
E3H47_13655	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E3H47_13675	ENOG4105WG9	Conserved Protein
E3H47_13680	ENOG4105D1H	recombination factor protein RarA
E3H47_13690	ENOG4105W1Y	Transcriptional regulator
E3H47_13700	ENOG4108ZZ3	UPF0260 protein
E3H47_13720	ENOG4105CEN	a g-specific adenine glycosylase
E3H47_13735	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E3H47_13740	ENOG4105DQ4	alcohol dehydrogenase
E3H47_13755	ENOG4105HEI	LysR family (Transcriptional regulator
E3H47_13760	ENOG4105CV8	reductase
E3H47_13765	ENOG4105F27	Major Facilitator
E3H47_13805	ENOG4108IG5	Transcriptional regulator
E3H47_13815	ENOG4105C2W	permease
E3H47_13820	ENOG4105EGI	Transcriptional regulator
E3H47_13830	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E3H47_13840	ENOG4105C01	Dihydroxy-acid dehydratase
E3H47_13850	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E3H47_13855	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
E3H47_13865	ENOG4105C8J	)-transporter
E3H47_13915	ENOG41067TZ	transcriptional regulator, MarR family
E3H47_13950	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E3H47_13975	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E3H47_13990	ENOG4105CVE	Lytic murein transglycosylase
E3H47_13995	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E3H47_14000	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E3H47_14010	ENOG4105DFU	Cell wall formation (By similarity)
E3H47_14015	ENOG4105CEY	Amp-dependent synthetase and ligase
E3H47_14020	ENOG4105CSU	acyl-Coa dehydrogenase
E3H47_14030	ENOG4107RGD	Major Facilitator superfamily
E3H47_14040	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E3H47_14050	ENOG4105DU1	integral membrane protein, terc
E3H47_14055	ENOG4107QUY	Guanine deaminase
E3H47_14060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E3H47_14070	ENOG4105T95	Thiol disulfide interChange protein
E3H47_14075	ENOG4105PGM	cation diffusion facilitator family transporter
E3H47_14090	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E3H47_14095	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E3H47_14100	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E3H47_14105	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E3H47_14110	ENOG4105VG0	50S ribosomal protein l34
E3H47_14155	ENOG4105E4P	ATPase (AAA
E3H47_14245	ENOG4105E3B	Multicopper oxidase
E3H47_14285	ENOG4105E3B	Multicopper oxidase
E3H47_14300	ENOG4105GR3	Histidine kinase
E3H47_14305	ENOG4107PU6	Membrane
E3H47_14310	ENOG4105C59	p-type ATPase
E3H47_14365	ENOG4108Z33	Thiol disulfide Interchange Protein
E3H47_14430	ENOG4105CE1	Ferrous iron transport protein b
E3H47_14475	ENOG41082YX	Transcriptional regulator, arsr family
E3H47_14485	ENOG4105D6J	arsenicaL-resistance protein
E3H47_14490	ENOG4105CAU	Arsenical resistance protein, ArsH
E3H47_14495	ENOG4105C3M	thioredoxin reductase
E3H47_14535	ENOG41080IJ	Diacylglycerol kinase
E3H47_14545	ENOG4105DHQ	Histidine kinase
E3H47_14550	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E3H47_14555	ENOG4105DIJ	Phosphoethanolamine transferase
E3H47_14600	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
E3H47_14635	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E3H47_14640	ENOG4107USA	Thioredoxin
E3H47_14645	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E3H47_14655	ENOG4105DHQ	Histidine kinase
E3H47_14680	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
E3H47_14760	ENOG4105EJX	conjugal transfer ATPase
E3H47_14835	ENOG4107QJE	Chromosome Partitioning Protein
E3H47_14865	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E3H47_14870	ENOG4105KT5	UmuD protein
E3H47_14930	ENOG4105EUV	Phenol 2-monooxygenase
E3H47_14970	ENOG4105DZR	Type I site-specific deoxyribonuclease
E3H47_14980	ENOG4105KT5	UmuD protein
E3H47_14990	ENOG4105K4U	addiction module toxin, RelE StbE family
E3H47_15010	ENOG4105H3G	oxidoreductase
E3H47_15045	ENOG4108JUA	Transcriptional regulator
E3H47_15050	ENOG4105DZR	Type I site-specific deoxyribonuclease
E3H47_15080	ENOG4107QJE	Chromosome Partitioning Protein
E3H47_15085	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
E3H47_15150	ENOG410626B	catechol 1,2-dioxygenase
E3H47_15155	ENOG4108MR5	
E3H47_15160	ENOG4108MZY	
E3H47_15165	ENOG4108KB2	LysR family Transcriptional regulator
E3H47_15170	ENOG4105DTQ	mandelate racemase muconate lactonizing
E3H47_15175	ENOG4105NN7	muconolactone delta-isomerase
E3H47_15180	ENOG4107QP7	CoA-transferase subunit A
E3H47_15185	ENOG4107QNJ	CoA-transferase subunit B
E3H47_15190	ENOG4105CHU	acetyl-coa acetyltransferase
E3H47_15195	ENOG4105F2Z	3-oxoadipate enol-lactonase
E3H47_15205	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
E3H47_15260	ENOG4108RZE	Tetr family transcriptional regulator
E3H47_15295	ENOG4107Z7P	Ferredoxin
E3H47_15300	ENOG4108R6W	Transcriptional regulator, ARAC family
E3H47_15355	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein