locus-tag	class	description
AsACE_CH00001	COG0592	DNA-directed DNA polymerase activity
AsACE_CH00003	COG0187	DNA topoisomerase II activity
AsACE_CH00005	COG1063	alcohol dehydrogenase
AsACE_CH00006	COG0488	(ABC) transporter
AsACE_CH00022	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AsACE_CH00028	COG2133	pyrroloquinoline quinone binding
AsACE_CH00030	COG1047	Peptidyl-prolyl cis-trans
AsACE_CH00032	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AsACE_CH00033	COG0196	riboflavin kinase activity
AsACE_CH00035	COG1309	transcriptional regulator
AsACE_CH00036	COG1116	anion transmembrane transporter activity
AsACE_CH00037	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AsACE_CH00038	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AsACE_CH00039	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AsACE_CH00040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AsACE_CH00041	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AsACE_CH00041	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AsACE_CH00046	COG1028	Short-chain dehydrogenase reductase Sdr
AsACE_CH00047	COG0546	phosphoglycolate phosphatase activity
AsACE_CH00048	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AsACE_CH00049	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AsACE_CH00051	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AsACE_CH00053	COG3023	N-Acetylmuramoyl-L-alanine amidase
AsACE_CH00054	COG0728	peptidoglycan biosynthetic process
AsACE_CH00055	COG5487	UPF0391 membrane protein
AsACE_CH00056	COG2983	Belongs to the UPF0260 family
AsACE_CH00057	COG5001	Diguanylate cyclase
AsACE_CH00057	COG3300	MHYT domain
AsACE_CH00058	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AsACE_CH00061	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AsACE_CH00063	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AsACE_CH00064	COG2814	Major facilitator Superfamily
AsACE_CH00065	COG1335	isochorismatase
AsACE_CH00066	COG0385	Bile acid
AsACE_CH00068	COG0560	Phosphoserine phosphatase
AsACE_CH00068	COG3830	Belongs to the UPF0237 family
AsACE_CH00073	COG0753	catalase activity
AsACE_CH00081	COG2733	membrane
AsACE_CH00084	COG2918	glutathione biosynthetic process
AsACE_CH00085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AsACE_CH00087	COG3150	esterase
AsACE_CH00092	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AsACE_CH00093	COG0410	ABC transporter
AsACE_CH00098	COG2205	protein histidine kinase activity
AsACE_CH00098	COG0784	Response regulator, receiver
AsACE_CH00103	COG4266	Belongs to the allantoicase family
AsACE_CH00104	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AsACE_CH00107	COG2233	PERMEase
AsACE_CH00108	COG2351	hydroxyisourate hydrolase activity
AsACE_CH00118	COG1393	Belongs to the ArsC family
AsACE_CH00119	COG0708	Exodeoxyribonuclease III
AsACE_CH00125	COG2132	Multicopper oxidase
AsACE_CH00128	COG0189	ligase activity
AsACE_CH00130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AsACE_CH00133	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AsACE_CH00135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AsACE_CH00141	COG2119	membrane
AsACE_CH00142	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AsACE_CH00142	COG0426	domain, Protein
AsACE_CH00145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AsACE_CH00147	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AsACE_CH00151	COG0640	Transcriptional regulator
AsACE_CH00152	COG1902	pentaerythritol trinitrate reductase activity
AsACE_CH00153	COG1519	Transferase
AsACE_CH00154	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AsACE_CH00155	COG0668	transmembrane transport
AsACE_CH00157	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AsACE_CH00160	COG0307	riboflavin synthase, alpha
AsACE_CH00162	COG0431	NADPH-dependent FMN reductase
AsACE_CH00166	COG0784	Response regulator, receiver
AsACE_CH00166	COG2205	protein histidine kinase activity
AsACE_CH00167	COG3162	membrane
AsACE_CH00169	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AsACE_CH00172	COG3706	GGDEF domain
AsACE_CH00173	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AsACE_CH00174	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AsACE_CH00174	COG0352	thiamine-phosphate diphosphorylase activity
AsACE_CH00174	COG0351	phosphomethylpyrimidine kinase
AsACE_CH00176	COG2814	Major facilitator Superfamily
AsACE_CH00180	COG0450	alkyl hydroperoxide reductase
AsACE_CH00182	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AsACE_CH00188	COG3158	transport of potassium into the cell
AsACE_CH00194	COG0107	imidazoleglycerol-phosphate synthase activity
AsACE_CH00195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AsACE_CH00204	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AsACE_CH00205	COG0131	Imidazoleglycerol-phosphate dehydratase
AsACE_CH00216	COG1024	Enoyl-CoA hydratase
AsACE_CH00216	COG1250	3-hydroxyacyl-CoA dehydrogenase
AsACE_CH00217	COG3706	GGDEF domain
AsACE_CH00220	COG0322	excinuclease ABC activity
AsACE_CH00222	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AsACE_CH00225	COG3275	phosphorelay sensor kinase activity
AsACE_CH00227	COG0181	hydroxymethylbilane synthase activity
AsACE_CH00231	COG0824	Thioesterase
AsACE_CH00237	COG0546	phosphoglycolate phosphatase activity
AsACE_CH00243	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AsACE_CH00247	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AsACE_CH00248	COG0081	regulation of translation
AsACE_CH00249	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AsACE_CH00251	COG0085	RNA polymerase activity
AsACE_CH00252	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AsACE_CH00258	COG2056	Na+-H+ antiporter family
AsACE_CH00261	COG0326	Molecular chaperone. Has ATPase activity
AsACE_CH00268	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AsACE_CH00270	COG0427	acetyl-CoA hydrolase
AsACE_CH00271	COG2205	protein histidine kinase activity
AsACE_CH00272	COG0745	RESPONSE REGULATOR receiver
AsACE_CH00276	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AsACE_CH00284	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AsACE_CH00285	COG1074	ATP-dependent DNA helicase activity
AsACE_CH00286	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AsACE_CH00287	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AsACE_CH00288	COG1185	polyribonucleotide nucleotidyltransferase activity
AsACE_CH00289	COG2841	Protein conserved in bacteria
AsACE_CH00290	COG0789	Transcriptional regulator
AsACE_CH00293	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AsACE_CH00295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AsACE_CH00299	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AsACE_CH00300	COG4535	Mg2 and Co2 transporter CorC
AsACE_CH00302	COG3501	Rhs element vgr protein
AsACE_CH00310	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AsACE_CH00310	COG0644	oxidoreductase
AsACE_CH00312	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AsACE_CH00315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AsACE_CH00318	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AsACE_CH00320	COG0493	'glutamate synthase
AsACE_CH00326	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AsACE_CH00334	COG0751	glycine-tRNA ligase activity
AsACE_CH00338	COG0471	metal ion transport
AsACE_CH00340	COG1983	PspC domain protein
AsACE_CH00346	COG1530	ribonuclease E activity
AsACE_CH00349	COG0546	phosphoglycolate phosphatase activity
AsACE_CH00350	COG3971	2-oxopent-4-enoate hydratase activity
AsACE_CH00351	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AsACE_CH00357	COG0583	DNA-binding transcription factor activity
AsACE_CH00358	COG4638	Rieske (2fe-2S)
AsACE_CH00361	COG1028	Short-chain dehydrogenase reductase Sdr
AsACE_CH00362	COG3384	dioxygenase
AsACE_CH00363	COG0446	pyridine nucleotide-disulphide oxidoreductase
AsACE_CH00366	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AsACE_CH00367	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH00376	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AsACE_CH00379	COG0473	3-isopropylmalate dehydrogenase activity
AsACE_CH00385	COG0252	asparaginase activity
AsACE_CH00390	COG1560	Kdo2-lipid A biosynthetic process
AsACE_CH00398	COG1929	Belongs to the glycerate kinase type-1 family
AsACE_CH00399	COG0210	DNA helicase
AsACE_CH00400	COG0724	RNA recognition motif
AsACE_CH00404	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AsACE_CH00404	COG4651	solute:proton antiporter activity
AsACE_CH00405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AsACE_CH00406	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AsACE_CH00409	COG0788	formyltetrahydrofolate deformylase activity
AsACE_CH00417	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AsACE_CH00427	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AsACE_CH00427	COG2813	Specifically methylates the guanine in position
AsACE_CH00428	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AsACE_CH00429	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AsACE_CH00432	COG4774	siderophore transport
AsACE_CH00434	COG3128	pkhd-type hydroxylase
AsACE_CH00435	COG4774	siderophore transport
AsACE_CH00436	COG4774	siderophore transport
AsACE_CH00438	COG0740	serine-type endopeptidase activity
AsACE_CH00441	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AsACE_CH00441	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AsACE_CH00443	COG0280	phosphate acetyltransferase
AsACE_CH00443	COG0857	belongs to the CobB CobQ family
AsACE_CH00444	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AsACE_CH00449	COG0793	Belongs to the peptidase S41A family
AsACE_CH00466	COG0084	hydrolase, TatD family'
AsACE_CH00468	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AsACE_CH00469	COG1002	Type II restriction enzyme, methylase subunits
AsACE_CH00470	COG1061	Type III restriction enzyme res subunit
AsACE_CH00472	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AsACE_CH00474	COG3293	Transposase
AsACE_CH00479	COG3293	Transposase
AsACE_CH00483	COG1401	restriction endodeoxyribonuclease activity
AsACE_CH00485	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AsACE_CH00488	COG0084	hydrolase, TatD family'
AsACE_CH00494	COG1162	GTPase activity
AsACE_CH00495	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AsACE_CH00497	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AsACE_CH00499	COG1538	Outer membrane efflux protein
AsACE_CH00500	COG1136	(ABC) transporter
AsACE_CH00500	COG0577	efflux transmembrane transporter activity
AsACE_CH00501	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AsACE_CH00506	COG0028	Belongs to the TPP enzyme family
AsACE_CH00507	COG0440	acetolactate synthase activity
AsACE_CH00514	COG2975	iron-sulfur cluster assembly
AsACE_CH00518	COG1426	Protein conserved in bacteria
AsACE_CH00520	COG0124	histidyl-tRNA synthetase
AsACE_CH00522	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AsACE_CH00525	COG1028	Short-chain dehydrogenase reductase Sdr
AsACE_CH00526	COG3956	TIGRFAM MazG family protein
AsACE_CH00527	COG1555	photosystem II stabilization
AsACE_CH00528	COG0617	tRNA 3'-terminal CCA addition
AsACE_CH00529	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AsACE_CH00532	COG1660	Displays ATPase and GTPase activities
AsACE_CH00536	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AsACE_CH00551	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AsACE_CH00558	COG0318	PFAM AMP-dependent synthetase and ligase
AsACE_CH00563	COG0546	phosphoglycolate phosphatase activity
AsACE_CH00565	COG0625	glutathione transferase activity
AsACE_CH00567	COG1238	metal cluster binding
AsACE_CH00570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AsACE_CH00573	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AsACE_CH00574	COG0072	phenylalanine-tRNA ligase activity
AsACE_CH00581	COG0037	tRNA processing
AsACE_CH00590	COG1764	response to oxidative stress
AsACE_CH00591	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AsACE_CH00601	COG2969	positive regulation of protein catabolic process
AsACE_CH00602	COG0625	glutathione transferase activity
AsACE_CH00603	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AsACE_CH00604	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AsACE_CH00605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AsACE_CH00606	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AsACE_CH00607	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AsACE_CH00612	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AsACE_CH00616	COG0494	nUDIX hydrolase
AsACE_CH00618	COG1214	PFAM Peptidase M22, glycoprotease
AsACE_CH00619	COG1968	undecaprenyl-diphosphatase activity
AsACE_CH00623	COG4269	membrane
AsACE_CH00626	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AsACE_CH00627	COG2076	Multidrug Resistance protein
AsACE_CH00628	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AsACE_CH00633	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AsACE_CH00634	COG3545	Serine hydrolase
AsACE_CH00635	COG3545	Serine hydrolase
AsACE_CH00637	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AsACE_CH00637	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AsACE_CH00638	COG0730	response to heat
AsACE_CH00640	COG1196	nuclear chromosome segregation
AsACE_CH00642	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AsACE_CH00643	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AsACE_CH00644	COG2193	ferroxidase activity
AsACE_CH00647	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AsACE_CH00648	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AsACE_CH00652	COG0009	L-threonylcarbamoyladenylate synthase
AsACE_CH00653	COG3101	peptidyl-lysine hydroxylation
AsACE_CH00654	COG1399	metal-binding, possibly nucleic acid-binding protein
AsACE_CH00655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AsACE_CH00657	COG1028	Short-chain dehydrogenase reductase Sdr
AsACE_CH00658	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AsACE_CH00659	COG1652	LysM domain
AsACE_CH00660	COG1522	sequence-specific DNA binding
AsACE_CH00663	COG0251	oxidation-reduction process
AsACE_CH00664	COG1113	amino acid transport
AsACE_CH00668	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AsACE_CH00671	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AsACE_CH00673	COG0456	acetyltransferase
AsACE_CH00674	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AsACE_CH00675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AsACE_CH00676	COG0492	ferredoxin-NADP+ reductase activity
AsACE_CH00677	COG0531	amino acid
AsACE_CH00677	COG1674	ftsk spoiiie
AsACE_CH00681	COG0850	regulation of cytokinetic process
AsACE_CH00683	COG0204	Acyl-transferase
AsACE_CH00684	COG2885	chlorophyll binding
AsACE_CH00686	COG0756	dUTP diphosphatase activity
AsACE_CH00687	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AsACE_CH00689	COG0121	glutamine amidotransferase
AsACE_CH00692	COG2914	Belongs to the UPF0125 (RnfH) family
AsACE_CH00693	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AsACE_CH00694	COG0735	belongs to the Fur family
AsACE_CH00700	COG0420	3'-5' exonuclease activity
AsACE_CH00703	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AsACE_CH00705	COG2050	protein possibly involved in aromatic compounds catabolism
AsACE_CH00706	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AsACE_CH00707	COG0582	viral genome integration into host DNA
AsACE_CH00716	COG0629	single-stranded DNA binding
AsACE_CH00717	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AsACE_CH00720	COG0625	glutathione transferase activity
AsACE_CH00723	COG1448	Aminotransferase
AsACE_CH00724	COG1113	amino acid transport
AsACE_CH00727	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AsACE_CH00728	COG0596	Alpha beta hydrolase
AsACE_CH00731	COG4106	trans-aconitate 2-methyltransferase activity
AsACE_CH00735	COG1271	oxidase subunit
AsACE_CH00736	COG1294	oxidase, subunit
AsACE_CH00738	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AsACE_CH00741	COG0471	metal ion transport
AsACE_CH00743	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AsACE_CH00744	COG0154	amidase activity
AsACE_CH00745	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AsACE_CH00746	COG1077	Cell shape determining protein MreB Mrl
AsACE_CH00747	COG1792	Involved in formation and maintenance of cell shape
AsACE_CH00748	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AsACE_CH00749	COG0424	maF-like protein
AsACE_CH00750	COG1530	ribonuclease E activity
AsACE_CH00752	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AsACE_CH00758	COG1113	amino acid transport
AsACE_CH00759	COG2828	Protein conserved in bacteria
AsACE_CH00760	COG0142	geranyltranstransferase activity
AsACE_CH00761	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AsACE_CH00764	COG1752	Esterase of the alpha-beta hydrolase superfamily
AsACE_CH00768	COG0546	phosphoglycolate phosphatase activity
AsACE_CH00769	COG2323	membrane
AsACE_CH00772	COG2852	Protein conserved in bacteria
AsACE_CH00775	COG0525	valine-tRNA ligase activity
AsACE_CH00777	COG0300	oxidoreductase activity
AsACE_CH00778	COG2066	Belongs to the glutaminase family
AsACE_CH00779	COG2376	Dihydroxyacetone kinase
AsACE_CH00780	COG2852	Protein conserved in bacteria
AsACE_CH00783	COG0306	phosphate transporter
AsACE_CH00792	COG4181	ATPase activity
AsACE_CH00793	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AsACE_CH00795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AsACE_CH00797	COG0583	DNA-binding transcription factor activity
AsACE_CH00799	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AsACE_CH00800	COG1773	rubredoxin
AsACE_CH00801	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AsACE_CH00805	COG2354	Protein conserved in bacteria
AsACE_CH00806	COG2321	neutral zinc metallopeptidase
AsACE_CH00813	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AsACE_CH00813	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AsACE_CH00816	COG2009	succinate dehydrogenase
AsACE_CH00817	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AsACE_CH00818	COG1053	succinate dehydrogenase
AsACE_CH00819	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AsACE_CH00822	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AsACE_CH00824	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AsACE_CH00826	COG0726	polysaccharide deacetylase
AsACE_CH00826	COG1649	PFAM Uncharacterised BCR, COG1649
AsACE_CH00827	COG1215	transferase activity, transferring glycosyl groups
AsACE_CH00829	COG0726	polysaccharide deacetylase
AsACE_CH00829	COG1649	PFAM Uncharacterised BCR, COG1649
AsACE_CH00830	COG2268	Band 7 protein
AsACE_CH00833	COG0175	sulfate reduction
AsACE_CH00843	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AsACE_CH00858	COG0742	ribosomal rna small subunit methyltransferase
AsACE_CH00859	COG0768	penicillin binding
AsACE_CH00864	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AsACE_CH00865	COG2878	Part of a membrane complex involved in electron transport
AsACE_CH00866	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AsACE_CH00868	COG3384	dioxygenase
AsACE_CH00870	COG2234	aminopeptidase activity
AsACE_CH00872	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AsACE_CH00880	COG0006	proline dipeptidase activity
AsACE_CH00882	COG2155	Conserved Protein
AsACE_CH00884	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AsACE_CH00885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AsACE_CH00895	COG0741	lytic transglycosylase activity
AsACE_CH00895	COG1388	LysM domain
AsACE_CH00896	COG4166	transmembrane transport
AsACE_CH00897	COG4174	ABC transporter (Permease)
AsACE_CH00898	COG4239	(ABC) transporter, permease
AsACE_CH00899	COG4172	Belongs to the ABC transporter superfamily
AsACE_CH00907	COG0833	amino acid
AsACE_CH00912	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AsACE_CH00913	COG0418	dihydroorotase activity
AsACE_CH00914	COG2203	Gaf domain
AsACE_CH00914	COG3706	GGDEF domain
AsACE_CH00914	COG4251	negative regulation of phosphorylation
AsACE_CH00914	COG5001	Diguanylate cyclase
AsACE_CH00916	COG1620	l-lactate permease
AsACE_CH00917	COG2186	Transcriptional regulator
AsACE_CH00919	COG0277	FAD linked oxidase domain protein
AsACE_CH00921	COG1902	pentaerythritol trinitrate reductase activity
AsACE_CH00921	COG0446	pyridine nucleotide-disulphide oxidoreductase
AsACE_CH00923	COG0642	Histidine kinase
AsACE_CH00924	COG0745	RESPONSE REGULATOR receiver
AsACE_CH00927	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AsACE_CH00930	COG0640	Transcriptional regulator
AsACE_CH00936	COG1741	Belongs to the pirin family
AsACE_CH00939	COG3739	integral membrane protein
AsACE_CH00942	COG3706	GGDEF domain
AsACE_CH00945	COG0302	gtp cyclohydrolase
AsACE_CH00948	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AsACE_CH00949	COG0512	Glutamine amidotransferase of anthranilate synthase
AsACE_CH00952	COG3161	chorismate lyase activity
AsACE_CH00953	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AsACE_CH00961	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AsACE_CH00963	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AsACE_CH00965	COG0596	Alpha beta hydrolase
AsACE_CH00966	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AsACE_CH00967	COG1335	isochorismatase
AsACE_CH00968	COG0251	oxidation-reduction process
AsACE_CH00969	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AsACE_CH00970	COG2233	PERMEase
AsACE_CH00971	COG2084	Dehydrogenase
AsACE_CH00973	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH00974	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AsACE_CH00975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AsACE_CH00983	COG0556	nucleotide-excision repair
AsACE_CH00988	COG1733	regulation of RNA biosynthetic process
AsACE_CH00989	COG2814	Major facilitator Superfamily
AsACE_CH00991	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AsACE_CH00992	COG0671	phosphoesterase, PA-phosphatase related
AsACE_CH00994	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AsACE_CH00995	COG0076	glutamate decarboxylase activity
AsACE_CH00997	COG0573	inorganic phosphate transmembrane transporter activity
AsACE_CH00999	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AsACE_CH01001	COG0616	signal peptide processing
AsACE_CH01009	COG5002	protein histidine kinase activity
AsACE_CH01013	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AsACE_CH01014	COG1686	Belongs to the peptidase S11 family
AsACE_CH01019	COG0583	DNA-binding transcription factor activity
AsACE_CH01020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AsACE_CH01021	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AsACE_CH01022	COG1067	ATP-dependent peptidase activity
AsACE_CH01030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AsACE_CH01031	COG1966	Carbon starvation protein
AsACE_CH01032	COG2879	small protein
AsACE_CH01033	COG0714	Associated with various cellular activities
AsACE_CH01039	COG0281	malic enzyme
AsACE_CH01040	COG3293	Transposase
AsACE_CH01044	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AsACE_CH01045	COG1765	OsmC-like protein
AsACE_CH01047	COG0667	Aldo Keto reductase
AsACE_CH01051	COG0540	Belongs to the ATCase OTCase family
AsACE_CH01053	COG2885	chlorophyll binding
AsACE_CH01053	COG3047	cAMP biosynthetic process
AsACE_CH01057	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AsACE_CH01058	COG0659	secondary active sulfate transmembrane transporter activity
AsACE_CH01063	COG2363	Small membrane protein
AsACE_CH01066	COG1278	Cold shock
AsACE_CH01067	COG0513	Belongs to the DEAD box helicase family
AsACE_CH01069	COG0778	Nitroreductase
AsACE_CH01080	COG4783	chaperone-mediated protein folding
AsACE_CH01083	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AsACE_CH01091	COG2815	serine threonine protein kinase
AsACE_CH01091	COG0515	serine threonine protein kinase
AsACE_CH01107	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AsACE_CH01108	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AsACE_CH01110	COG0612	Peptidase, M16
AsACE_CH01115	COG3025	triphosphatase activity
AsACE_CH01119	COG0352	thiamine-phosphate diphosphorylase activity
AsACE_CH01129	COG1309	transcriptional regulator
AsACE_CH01143	COG2391	methyltransferase activity
AsACE_CH01145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AsACE_CH01146	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AsACE_CH01148	COG0456	acetyltransferase
AsACE_CH01149	COG2353	YceI-like domain
AsACE_CH01150	COG0519	Catalyzes the synthesis of GMP from XMP
AsACE_CH01150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AsACE_CH01154	COG1028	Short-chain dehydrogenase reductase Sdr
AsACE_CH01157	COG2801	Transposase and inactivated derivatives
AsACE_CH01158	COG2963	transposase activity
AsACE_CH01162	COG0517	IMP dehydrogenase activity
AsACE_CH01162	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AsACE_CH01163	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AsACE_CH01165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AsACE_CH01166	COG1137	ATPase activity
AsACE_CH01167	COG1538	Outer membrane efflux protein
AsACE_CH01172	COG0589	response to stress
AsACE_CH01175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AsACE_CH01183	COG2011	ABC-type metal ion transport system permease component
AsACE_CH01184	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AsACE_CH01185	COG1464	Belongs to the NlpA lipoprotein family
AsACE_CH01188	COG0151	Belongs to the GarS family
AsACE_CH01189	COG0138	bifunctional purine biosynthesis protein purh
AsACE_CH01190	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AsACE_CH01196	COG0445	tRNA wobble uridine modification
AsACE_CH01202	COG2204	response regulator
AsACE_CH01203	COG3852	Histidine kinase
AsACE_CH01207	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AsACE_CH01208	COG0575	Belongs to the CDS family
AsACE_CH01211	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AsACE_CH01213	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AsACE_CH01214	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AsACE_CH01215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AsACE_CH01217	COG2137	regulation of response to DNA damage stimulus
AsACE_CH01219	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AsACE_CH01220	COG1011	Hydrolase
AsACE_CH01221	COG1218	3'(2'),5'-bisphosphate nucleotidase
AsACE_CH01223	COG0268	Binds directly to 16S ribosomal RNA
AsACE_CH01224	COG0702	epimerase
AsACE_CH01225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AsACE_CH01226	COG0625	glutathione transferase activity
AsACE_CH01227	COG2850	peptidyl-arginine hydroxylation
AsACE_CH01229	COG0424	maF-like protein
AsACE_CH01234	COG0697	spore germination
AsACE_CH01239	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AsACE_CH01240	COG3781	membrane
AsACE_CH01244	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AsACE_CH01244	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AsACE_CH01244	COG0506	proline dehydrogenase activity
AsACE_CH01246	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AsACE_CH01247	COG1027	Aspartate ammonia-lyase
AsACE_CH01249	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AsACE_CH01255	COG0316	Belongs to the HesB IscA family
AsACE_CH01256	COG0822	iron-sulfur transferase activity
AsACE_CH01261	COG0776	regulation of translation
AsACE_CH01262	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AsACE_CH01266	COG1585	Membrane protein implicated in regulation of membrane protease activity
AsACE_CH01268	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AsACE_CH01272	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AsACE_CH01273	COG0569	domain protein
AsACE_CH01274	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AsACE_CH01275	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AsACE_CH01282	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AsACE_CH01283	COG0542	response to heat
AsACE_CH01286	COG0477	Major facilitator Superfamily
AsACE_CH01290	COG0372	Belongs to the citrate synthase family
AsACE_CH01292	COG1546	Belongs to the CinA family
AsACE_CH01292	COG1058	Belongs to the CinA family
AsACE_CH01302	COG2814	Major facilitator Superfamily
AsACE_CH01304	COG3706	GGDEF domain
AsACE_CH01306	COG0439	Biotin carboxylase
AsACE_CH01309	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AsACE_CH01314	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AsACE_CH01315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AsACE_CH01321	COG0596	Alpha beta hydrolase
AsACE_CH01351	COG3550	peptidyl-serine autophosphorylation
AsACE_CH01353	COG3604	Transcriptional regulator
AsACE_CH01359	COG4221	oxidoreductase activity
AsACE_CH01362	COG0642	Histidine kinase
AsACE_CH01363	COG0745	RESPONSE REGULATOR receiver
AsACE_CH01364	COG2194	sulfuric ester hydrolase activity
AsACE_CH01367	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AsACE_CH01368	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AsACE_CH01372	COG0515	serine threonine protein kinase
AsACE_CH01373	COG2116	formate transmembrane transporter activity
AsACE_CH01374	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AsACE_CH01376	COG0402	S-adenosylhomocysteine deaminase activity
AsACE_CH01385	COG0583	DNA-binding transcription factor activity
AsACE_CH01387	COG1877	trehalose-phosphatase activity
AsACE_CH01388	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AsACE_CH01394	COG1944	ATP diphosphatase activity
AsACE_CH01398	COG1309	transcriptional regulator
AsACE_CH01399	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AsACE_CH01403	COG0347	Belongs to the P(II) protein family
AsACE_CH01405	COG2223	nitrite transmembrane transporter activity
AsACE_CH01406	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AsACE_CH01407	COG4149	molybdate abc transporter
AsACE_CH01408	COG0725	ABC transporter, periplasmic molybdate-binding protein
AsACE_CH01409	COG0303	'Molybdopterin
AsACE_CH01410	COG0521	Mo-molybdopterin cofactor biosynthetic process
AsACE_CH01410	COG0315	cyclic pyranopterin monophosphate synthase activity
AsACE_CH01411	COG0314	molybdopterin synthase activity
AsACE_CH01413	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AsACE_CH01415	COG0243	molybdopterin cofactor binding
AsACE_CH01416	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AsACE_CH01417	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AsACE_CH01418	COG2223	nitrite transmembrane transporter activity
AsACE_CH01420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AsACE_CH01420	COG1116	anion transmembrane transporter activity
AsACE_CH01421	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AsACE_CH01422	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AsACE_CH01427	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AsACE_CH01429	COG0864	Transcriptional regulator
AsACE_CH01435	COG0318	PFAM AMP-dependent synthetase and ligase
AsACE_CH01438	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01440	COG1024	Enoyl-CoA hydratase
AsACE_CH01441	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AsACE_CH01442	COG0235	Class ii aldolase
AsACE_CH01444	COG0183	Belongs to the thiolase family
AsACE_CH01445	COG1250	3-hydroxyacyl-CoA dehydrogenase
AsACE_CH01447	COG2814	Major facilitator Superfamily
AsACE_CH01449	COG2814	Major facilitator Superfamily
AsACE_CH01450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AsACE_CH01451	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AsACE_CH01452	COG2814	Major facilitator Superfamily
AsACE_CH01453	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01454	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01456	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AsACE_CH01456	COG0644	oxidoreductase
AsACE_CH01457	COG0439	Biotin carboxylase
AsACE_CH01460	COG0583	DNA-binding transcription factor activity
AsACE_CH01461	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AsACE_CH01465	COG0318	PFAM AMP-dependent synthetase and ligase
AsACE_CH01467	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AsACE_CH01469	COG2814	Major facilitator Superfamily
AsACE_CH01470	COG0583	DNA-binding transcription factor activity
AsACE_CH01471	COG4948	Mandelate Racemase Muconate Lactonizing
AsACE_CH01472	COG4829	muconolactone delta-isomerase
AsACE_CH01474	COG4638	Rieske (2fe-2S)
AsACE_CH01475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AsACE_CH01476	COG0543	2 iron, 2 sulfur cluster binding
AsACE_CH01476	COG0633	Ferredoxin
AsACE_CH01477	COG1028	Short-chain dehydrogenase reductase Sdr
AsACE_CH01478	COG3135	benzoate transporter
AsACE_CH01479	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AsACE_CH01480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AsACE_CH01481	COG0183	Belongs to the thiolase family
AsACE_CH01482	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AsACE_CH01485	COG0804	urea catabolic process
AsACE_CH01488	COG0829	nickel cation binding
AsACE_CH01490	COG0830	nickel cation binding
AsACE_CH01495	COG0789	Transcriptional regulator
AsACE_CH01497	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AsACE_CH01498	COG0640	Transcriptional regulator
AsACE_CH01501	COG3619	membrane
AsACE_CH01502	COG3122	Protein conserved in bacteria
AsACE_CH01505	COG0668	transmembrane transport
AsACE_CH01506	COG1132	(ABC) transporter
AsACE_CH01509	COG0509	glycine decarboxylation via glycine cleavage system
AsACE_CH01510	COG2814	Major facilitator Superfamily
AsACE_CH01513	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AsACE_CH01515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AsACE_CH01516	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AsACE_CH01528	COG1525	nuclease
AsACE_CH01532	COG2169	Transcriptional regulator
AsACE_CH01533	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01534	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AsACE_CH01535	COG2207	Transcriptional regulator
AsACE_CH01536	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AsACE_CH01537	COG0730	response to heat
AsACE_CH01538	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AsACE_CH01549	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01550	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01568	COG0552	protein localization to endoplasmic reticulum
AsACE_CH01569	COG0612	Peptidase, M16
AsACE_CH01575	COG0517	IMP dehydrogenase activity
AsACE_CH01576	COG0133	tryptophan synthase activity
AsACE_CH01578	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AsACE_CH01582	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AsACE_CH01589	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AsACE_CH01592	COG1294	oxidase, subunit
AsACE_CH01596	COG0772	Belongs to the SEDS family
AsACE_CH01598	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AsACE_CH01599	COG0148	phosphopyruvate hydratase activity
AsACE_CH01605	COG0446	pyridine nucleotide-disulphide oxidoreductase
AsACE_CH01605	COG1902	pentaerythritol trinitrate reductase activity
AsACE_CH01608	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AsACE_CH01609	COG0583	DNA-binding transcription factor activity
AsACE_CH01610	COG0024	Methionine aminopeptidase
AsACE_CH01611	COG1114	Component of the transport system for branched-chain amino acids
AsACE_CH01615	COG0786	glutamate:sodium symporter activity
AsACE_CH01623	COG1570	exodeoxyribonuclease VII activity
AsACE_CH01627	COG0729	surface antigen
AsACE_CH01628	COG0477	Major facilitator Superfamily
AsACE_CH01629	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AsACE_CH01634	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AsACE_CH01640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AsACE_CH01641	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AsACE_CH01642	COG2890	protein-(glutamine-N5) methyltransferase activity
AsACE_CH01643	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AsACE_CH01646	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AsACE_CH01651	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AsACE_CH01652	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AsACE_CH01653	COG1845	cytochrome c oxidase, subunit III
AsACE_CH01654	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AsACE_CH01656	COG0360	Binds together with S18 to 16S ribosomal RNA
AsACE_CH01659	COG0305	Participates in initiation and elongation during chromosome replication
AsACE_CH01660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AsACE_CH01663	COG1305	Transglutaminase-like
AsACE_CH01665	COG2308	Evidence 4 Homologs of previously reported genes of
AsACE_CH01667	COG0069	glutamate synthase activity
AsACE_CH01670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AsACE_CH01671	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AsACE_CH01672	COG1454	alcohol dehydrogenase
AsACE_CH01673	COG0824	Thioesterase
AsACE_CH01679	COG0183	Belongs to the thiolase family
AsACE_CH01682	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AsACE_CH01684	COG3135	benzoate transporter
AsACE_CH01686	COG0589	response to stress
AsACE_CH01687	COG0589	response to stress
AsACE_CH01689	COG0308	aminopeptidase N
AsACE_CH01695	COG1253	flavin adenine dinucleotide binding
AsACE_CH01700	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AsACE_CH01703	COG2431	L-lysine efflux transmembrane transporter activity
AsACE_CH01707	COG0776	regulation of translation
AsACE_CH01711	COG0590	tRNA wobble adenosine to inosine editing
AsACE_CH01713	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AsACE_CH01720	COG0084	hydrolase, TatD family'
AsACE_CH01724	COG1663	tetraacyldisaccharide 4'-kinase activity
AsACE_CH01725	COG1132	(ABC) transporter
AsACE_CH01727	COG0811	peptide transport
AsACE_CH01728	COG1475	DNA binding
AsACE_CH01729	COG1192	Involved in chromosome partitioning
AsACE_CH01731	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AsACE_CH01732	COG3178	'Phosphotransferase
AsACE_CH01734	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AsACE_CH01735	COG1923	regulation of RNA biosynthetic process
AsACE_CH01737	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AsACE_CH01738	COG0802	atpase or kinase
AsACE_CH01739	COG0564	pseudouridine synthase activity
AsACE_CH01745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AsACE_CH01749	COG1643	Atp-dependent helicase
AsACE_CH01750	COG0450	alkyl hydroperoxide reductase
AsACE_CH01755	COG3634	alkyl hydroperoxide reductase activity
AsACE_CH01761	COG1254	Belongs to the acylphosphatase family
AsACE_CH01762	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AsACE_CH01762	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AsACE_CH01768	COG2801	Transposase and inactivated derivatives
AsACE_CH01769	COG2963	transposase activity
AsACE_CH01771	COG0204	Acyl-transferase
AsACE_CH01779	COG1464	Belongs to the NlpA lipoprotein family
AsACE_CH01780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AsACE_CH01781	COG2011	ABC-type metal ion transport system permease component
AsACE_CH01782	COG0012	GTP binding
AsACE_CH01786	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AsACE_CH01789	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AsACE_CH01792	COG0386	Belongs to the glutathione peroxidase family
AsACE_CH01793	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AsACE_CH01794	COG0436	Aminotransferase
AsACE_CH01795	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AsACE_CH01795	COG2755	lipolytic protein G-D-S-L family
AsACE_CH01799	COG2351	hydroxyisourate hydrolase activity
AsACE_CH01803	COG1252	NADH dehydrogenase
AsACE_CH01804	COG1047	Peptidyl-prolyl cis-trans
AsACE_CH01807	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AsACE_CH01810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AsACE_CH01812	COG0527	aspartate kinase activity
AsACE_CH01815	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AsACE_CH01818	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AsACE_CH01819	COG2252	PERMEase
AsACE_CH01824	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AsACE_CH01825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AsACE_CH01827	COG0693	protein deglycase activity
AsACE_CH01828	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH01829	COG1301	dicarboxylic acid transport
AsACE_CH01831	COG3139	Protein of unknown function (DUF1315)
AsACE_CH01832	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AsACE_CH01833	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AsACE_CH01835	COG0494	nUDIX hydrolase
AsACE_CH01837	COG0642	Histidine kinase
AsACE_CH01838	COG0745	RESPONSE REGULATOR receiver
AsACE_CH01840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AsACE_CH01842	COG1720	tRNA m6t6A37 methyltransferase activity
AsACE_CH01845	COG0789	Transcriptional regulator
AsACE_CH01847	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AsACE_CH01848	COG3634	alkyl hydroperoxide reductase activity
AsACE_CH01852	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AsACE_CH01862	COG1278	Cold shock
AsACE_CH01867	COG0629	single-stranded DNA binding
AsACE_CH01876	COG0582	viral genome integration into host DNA
AsACE_CH01878	COG1131	(ABC) transporter
AsACE_CH01879	COG0842	Transport permease protein
AsACE_CH01882	COG2951	lytic endotransglycosylase activity
AsACE_CH01887	COG0052	Belongs to the universal ribosomal protein uS2 family
AsACE_CH01888	COG0024	Methionine aminopeptidase
AsACE_CH01895	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AsACE_CH01896	COG1381	Involved in DNA repair and RecF pathway recombination
AsACE_CH01898	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AsACE_CH01899	COG0571	ribonuclease III activity
AsACE_CH01904	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AsACE_CH01909	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AsACE_CH01911	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AsACE_CH01912	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AsACE_CH01915	COG4208	sulfate ABC transporter
AsACE_CH01916	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AsACE_CH01917	COG0583	DNA-binding transcription factor activity
AsACE_CH01920	COG0602	queuosine metabolic process
AsACE_CH01921	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AsACE_CH01923	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AsACE_CH01926	COG0583	DNA-binding transcription factor activity
AsACE_CH01927	COG1051	belongs to the nudix hydrolase family
AsACE_CH01927	COG1056	cytidyltransferase-related domain
AsACE_CH01928	COG1024	Enoyl-CoA hydratase
AsACE_CH01929	COG0778	Nitroreductase
AsACE_CH01935	COG0047	phosphoribosylformylglycinamidine synthase activity
AsACE_CH01935	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AsACE_CH01938	COG2255	four-way junction helicase activity
AsACE_CH01941	COG1473	amidohydrolase
AsACE_CH01943	COG0824	Thioesterase
AsACE_CH01947	COG0823	Involved in the tonB-independent uptake of proteins
AsACE_CH01951	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AsACE_CH01958	COG0628	permease
AsACE_CH01959	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AsACE_CH01960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AsACE_CH01964	COG2333	competence protein COMEC
AsACE_CH01964	COG0658	competence protein
AsACE_CH01965	COG1136	(ABC) transporter
AsACE_CH01966	COG4591	ABC-type transport system involved in lipoprotein release permease component
AsACE_CH01969	COG1671	Belongs to the UPF0178 family
AsACE_CH01974	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AsACE_CH01982	COG1280	lysine exporter protein (LysE YggA)
AsACE_CH01985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AsACE_CH01987	COG0019	diaminopimelate decarboxylase activity
AsACE_CH01989	COG1113	amino acid transport
AsACE_CH01990	COG1115	amino acid carrier protein
AsACE_CH01997	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AsACE_CH01998	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AsACE_CH01999	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AsACE_CH02000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AsACE_CH02005	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AsACE_CH02007	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AsACE_CH02008	COG2814	Major facilitator Superfamily
AsACE_CH02009	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH02010	COG0583	DNA-binding transcription factor activity
AsACE_CH02013	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AsACE_CH02014	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AsACE_CH02016	COG0037	tRNA processing
AsACE_CH02017	COG0741	lytic transglycosylase activity
AsACE_CH02017	COG0739	heme binding
AsACE_CH02017	COG1196	nuclear chromosome segregation
AsACE_CH02018	COG0501	Belongs to the peptidase M48B family
AsACE_CH02020	COG2239	Acts as a magnesium transporter
AsACE_CH02024	COG1253	flavin adenine dinucleotide binding
AsACE_CH02025	COG2851	Citrate transporter
AsACE_CH02031	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AsACE_CH02033	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AsACE_CH02034	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AsACE_CH02039	COG0505	Belongs to the CarA family
AsACE_CH02042	COG1309	transcriptional regulator
AsACE_CH02043	COG0251	oxidation-reduction process
AsACE_CH02044	COG0110	maltose O-acetyltransferase activity
AsACE_CH02047	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AsACE_CH02052	COG0564	pseudouridine synthase activity
AsACE_CH02054	COG0358	DNA primase activity
AsACE_CH02055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AsACE_CH02057	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AsACE_CH02063	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AsACE_CH02064	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AsACE_CH02069	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AsACE_CH02074	COG0586	Pfam SNARE associated Golgi protein
AsACE_CH02081	COG0321	lipoyl(octanoyl) transferase activity
AsACE_CH02084	COG0531	amino acid
AsACE_CH02086	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AsACE_CH02087	COG1648	precorrin-2 dehydrogenase activity
AsACE_CH02087	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AsACE_CH02088	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AsACE_CH02090	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AsACE_CH02092	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AsACE_CH02095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AsACE_CH02097	COG1538	Outer membrane efflux protein
AsACE_CH02098	COG0393	Putative heavy-metal-binding
AsACE_CH02099	COG0393	Putative heavy-metal-binding
AsACE_CH02100	COG0242	peptide deformylase activity
AsACE_CH02106	COG3706	GGDEF domain
AsACE_CH02106	COG5001	Diguanylate cyclase
AsACE_CH02106	COG2203	Gaf domain
AsACE_CH02106	COG4251	negative regulation of phosphorylation
AsACE_CH02108	COG1285	pathogenesis
AsACE_CH02109	COG4681	YaeQ
AsACE_CH02110	COG0523	cobalamin synthesis protein
AsACE_CH02114	COG0583	DNA-binding transcription factor activity
AsACE_CH02115	COG2814	Major facilitator Superfamily
AsACE_CH02116	COG1309	transcriptional regulator
AsACE_CH02117	COG1607	acyl-coa hydrolase
AsACE_CH02119	COG1752	Esterase of the alpha-beta hydrolase superfamily
AsACE_CH02121	COG1115	amino acid carrier protein
AsACE_CH02122	COG0786	glutamate:sodium symporter activity
AsACE_CH02124	COG2814	Major facilitator Superfamily
AsACE_CH02125	COG1289	transmembrane transporter activity
AsACE_CH02127	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AsACE_CH02143	COG0840	transmembrane signaling receptor activity
AsACE_CH02148	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AsACE_CH02157	COG0489	protein tyrosine kinase activity
AsACE_CH02160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AsACE_CH02160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AsACE_CH02164	COG0004	ammonium transporteR
AsACE_CH02167	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AsACE_CH02169	COG2081	HI0933 family
AsACE_CH02172	COG0668	transmembrane transport
AsACE_CH02174	COG4302	ethanolamine ammonia-lyase activity
AsACE_CH02175	COG4303	Ethanolamine ammonia lyase large subunit
AsACE_CH02179	COG0583	DNA-binding transcription factor activity
AsACE_CH02185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AsACE_CH02186	COG0713	ATP synthesis coupled electron transport
AsACE_CH02188	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AsACE_CH02191	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AsACE_CH02195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AsACE_CH02198	COG2205	protein histidine kinase activity
AsACE_CH02199	COG0745	RESPONSE REGULATOR receiver
AsACE_CH02200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AsACE_CH02200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AsACE_CH02201	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AsACE_CH02203	COG0640	Transcriptional regulator
AsACE_CH02204	COG0798	PFAM Bile acid sodium symporter
AsACE_CH02205	COG0431	NADPH-dependent FMN reductase
AsACE_CH02206	COG4772	TonB-dependent receptor
AsACE_CH02212	COG0351	phosphomethylpyrimidine kinase
AsACE_CH02212	COG0352	thiamine-phosphate diphosphorylase activity
AsACE_CH02212	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AsACE_CH02215	COG2824	Alkylphosphonate utilization operon protein PhnA
AsACE_CH02218	COG0564	pseudouridine synthase activity
AsACE_CH02227	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AsACE_CH02228	COG2132	Multicopper oxidase
AsACE_CH02229	COG0354	folic acid binding
AsACE_CH02233	COG1902	pentaerythritol trinitrate reductase activity
AsACE_CH02236	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AsACE_CH02239	COG2233	PERMEase
AsACE_CH02241	COG0833	amino acid
AsACE_CH02243	COG2885	chlorophyll binding
AsACE_CH02243	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AsACE_CH02245	COG0183	Belongs to the thiolase family
AsACE_CH02248	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AsACE_CH02250	COG2207	Transcriptional regulator
AsACE_CH02251	COG0183	Belongs to the thiolase family
AsACE_CH02252	COG1024	Enoyl-CoA hydratase
AsACE_CH02252	COG1250	3-hydroxyacyl-CoA dehydrogenase
AsACE_CH02256	COG1272	protein, Hemolysin III
AsACE_CH02257	COG0477	Major facilitator Superfamily
AsACE_CH02259	COG1408	metallophosphoesterase
AsACE_CH02260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AsACE_CH02269	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AsACE_CH02270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AsACE_CH02284	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AsACE_CH02285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AsACE_CH02288	COG0450	alkyl hydroperoxide reductase
AsACE_CH02291	COG0285	dihydrofolate synthase activity
AsACE_CH02293	COG0159	tryptophan synthase activity
AsACE_CH02298	COG0133	tryptophan synthase activity
AsACE_CH02300	COG4206	TonB-dependent receptor
AsACE_CH02301	COG2096	Adenosyltransferase
AsACE_CH02307	COG1113	amino acid transport
AsACE_CH02308	COG0745	RESPONSE REGULATOR receiver
AsACE_CH02309	COG2205	protein histidine kinase activity
AsACE_CH02311	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH02312	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH02314	COG3223	Belongs to the PsiE family
AsACE_CH02318	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AsACE_CH02320	COG1704	LemA family
AsACE_CH02323	COG1862	Preprotein translocase
AsACE_CH02325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AsACE_CH02327	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AsACE_CH02330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AsACE_CH02331	COG0784	Response regulator, receiver
AsACE_CH02331	COG5002	protein histidine kinase activity
AsACE_CH02331	COG2205	protein histidine kinase activity
AsACE_CH02332	COG1024	Enoyl-CoA hydratase
AsACE_CH02333	COG2084	Dehydrogenase
AsACE_CH02334	COG3622	Belongs to the hyi family
AsACE_CH02337	COG0004	ammonium transporteR
AsACE_CH02338	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AsACE_CH02339	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AsACE_CH02340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AsACE_CH02341	COG2814	Major facilitator Superfamily
AsACE_CH02346	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AsACE_CH02347	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AsACE_CH02348	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AsACE_CH02350	COG3293	Transposase
AsACE_CH02352	COG0183	Belongs to the thiolase family
AsACE_CH02353	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AsACE_CH02354	COG3706	GGDEF domain
AsACE_CH02359	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AsACE_CH02366	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AsACE_CH02367	COG0625	glutathione transferase activity
AsACE_CH02374	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AsACE_CH02376	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AsACE_CH02379	COG2009	succinate dehydrogenase
AsACE_CH02382	COG0732	type I restriction modification DNA specificity domain
AsACE_CH02384	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AsACE_CH02399	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AsACE_CH02401	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AsACE_CH02402	COG2003	Belongs to the UPF0758 family
AsACE_CH02403	COG3781	membrane
AsACE_CH02408	COG2350	Protein conserved in bacteria
AsACE_CH02414	COG1607	acyl-coa hydrolase
AsACE_CH02417	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AsACE_CH02417	COG3453	Protein conserved in bacteria
AsACE_CH02420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AsACE_CH02421	COG1283	sodium-dependent phosphate transmembrane transporter activity
AsACE_CH02428	COG1183	phosphatidylcholine synthase activity
AsACE_CH02429	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AsACE_CH02437	COG0739	heme binding
AsACE_CH02437	COG0741	lytic transglycosylase activity
AsACE_CH02437	COG1196	nuclear chromosome segregation
AsACE_CH02438	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AsACE_CH02439	COG1702	phosphate starvation-inducible protein PhoH
AsACE_CH02452	COG1295	ribonuclease BN
AsACE_CH02455	COG0179	Fumarylacetoacetate (FAA) hydrolase
AsACE_CH02463	COG0557	exoribonuclease II activity
AsACE_CH02465	COG0339	signal peptide processing
AsACE_CH02466	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AsACE_CH02473	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AsACE_CH02474	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH02475	COG2072	flavoprotein involved in K transport
AsACE_CH02476	COG0203	ribosomal protein L17
AsACE_CH02477	COG0202	RNA polymerase activity
AsACE_CH02478	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AsACE_CH02479	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AsACE_CH02480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AsACE_CH02481	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AsACE_CH02485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AsACE_CH02487	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AsACE_CH02488	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AsACE_CH02498	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AsACE_CH02500	COG0089	rRNA binding
AsACE_CH02501	COG0088	Forms part of the polypeptide exit tunnel
AsACE_CH02505	COG0626	cystathionine gamma-synthase activity
AsACE_CH02506	COG0433	COG0433 Predicted ATPase
AsACE_CH02507	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AsACE_CH02507	COG1017	nitric oxide dioxygenase activity
AsACE_CH02508	COG1959	2 iron, 2 sulfur cluster binding
AsACE_CH02512	COG1301	dicarboxylic acid transport
AsACE_CH02514	COG1946	Acyl-CoA thioesterase
AsACE_CH02515	COG2937	Belongs to the GPAT DAPAT family
AsACE_CH02517	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AsACE_CH02518	COG1040	competence protein
AsACE_CH02519	COG0494	nUDIX hydrolase
AsACE_CH02521	COG0598	Magnesium transport protein CorA
AsACE_CH02523	COG2854	intermembrane phospholipid transfer
AsACE_CH02524	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AsACE_CH02525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AsACE_CH02526	COG1127	ABC transporter
AsACE_CH02531	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AsACE_CH02532	COG0408	coproporphyrinogen oxidase activity
AsACE_CH02535	COG1960	acyl-CoA dehydrogenase activity
AsACE_CH02536	COG1278	Cold shock
AsACE_CH02538	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AsACE_CH02540	COG0534	Mate efflux family protein
AsACE_CH02543	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AsACE_CH02544	COG0254	rRNA binding
AsACE_CH02545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AsACE_CH02551	COG1192	Involved in chromosome partitioning
AsACE_CH02552	COG0628	permease
AsACE_CH02554	COG2814	Major facilitator Superfamily
AsACE_CH02557	COG0277	FAD linked oxidase domain protein
AsACE_CH02558	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AsACE_CH02559	COG5006	permease, DMT superfamily
AsACE_CH02563	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AsACE_CH02564	COG5380	lipid catabolic process
AsACE_CH02565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AsACE_CH02568	COG0335	large ribosomal subunit rRNA binding
AsACE_CH02570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AsACE_CH02571	COG0228	four-way junction DNA binding
AsACE_CH02580	COG0194	GDP metabolic process
AsACE_CH02581	COG1758	RNA polymerase activity
AsACE_CH02582	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AsACE_CH02584	COG2906	2 iron, 2 sulfur cluster binding
AsACE_CH02586	COG3307	-O-antigen
AsACE_CH02588	COG3307	-O-antigen
AsACE_CH02592	COG1704	LemA family
AsACE_CH02593	COG0493	'glutamate synthase
AsACE_CH02594	COG0067	glutamate synthase
AsACE_CH02594	COG0070	glutamate synthase
AsACE_CH02594	COG0069	glutamate synthase activity
AsACE_CH02604	COG2226	methyltransferase
AsACE_CH02605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AsACE_CH02606	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AsACE_CH02607	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AsACE_CH02611	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AsACE_CH02619	COG0488	(ABC) transporter
AsACE_CH02621	COG4221	oxidoreductase activity
AsACE_CH02622	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AsACE_CH02625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AsACE_CH02625	COG2111	Na H antiporter
AsACE_CH02626	COG1006	Multisubunit Na H antiporter MnhC subunit
AsACE_CH02627	COG0651	ATP synthesis coupled electron transport
AsACE_CH02628	COG1863	multisubunit Na H antiporter MnhE subunit
AsACE_CH02629	COG2212	antiporter activity
AsACE_CH02631	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AsACE_CH02632	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AsACE_CH02633	COG0195	Participates in both transcription termination and antitermination
AsACE_CH02634	COG0779	Required for maturation of 30S ribosomal subunits
AsACE_CH02640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AsACE_CH02645	COG0237	dephospho-CoA kinase activity
AsACE_CH02647	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AsACE_CH02648	COG3123	guanosine phosphorylase activity
AsACE_CH02649	COG0497	DNA recombination
AsACE_CH02651	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AsACE_CH02653	COG1132	(ABC) transporter
AsACE_CH02656	COG1538	Outer membrane efflux protein
AsACE_CH02658	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AsACE_CH02659	COG0494	nUDIX hydrolase
AsACE_CH02660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AsACE_CH02661	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AsACE_CH02662	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AsACE_CH02664	COG0772	Belongs to the SEDS family
AsACE_CH02669	COG4974	Belongs to the 'phage' integrase family
AsACE_CH02670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AsACE_CH02672	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AsACE_CH02674	COG2197	response regulator
AsACE_CH02675	COG5002	protein histidine kinase activity
AsACE_CH02677	COG0793	Belongs to the peptidase S41A family
AsACE_CH02678	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AsACE_CH02679	COG0795	lipopolysaccharide-transporting ATPase activity
AsACE_CH02680	COG0795	lipopolysaccharide-transporting ATPase activity
AsACE_CH02684	COG0586	Pfam SNARE associated Golgi protein
AsACE_CH02687	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AsACE_CH02687	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AsACE_CH02689	COG0004	ammonium transporteR
AsACE_CH02690	COG0347	Belongs to the P(II) protein family
AsACE_CH02692	COG0606	chelatase, subunit chli
AsACE_CH02696	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AsACE_CH02699	COG0318	PFAM AMP-dependent synthetase and ligase
AsACE_CH02701	COG0477	Major facilitator Superfamily
AsACE_CH02702	COG2860	membrane
AsACE_CH02704	COG1253	flavin adenine dinucleotide binding
AsACE_CH02710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AsACE_CH02711	COG0477	Major facilitator Superfamily
AsACE_CH02715	COG2814	Major facilitator Superfamily
AsACE_CH02725	COG0758	DNA mediated transformation
AsACE_CH02727	COG0697	spore germination
AsACE_CH02728	COG0386	Belongs to the glutathione peroxidase family
AsACE_CH02731	COG1012	belongs to the aldehyde dehydrogenase family
AsACE_CH02733	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AsACE_CH02743	COG1121	(ABC) transporter
AsACE_CH02744	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AsACE_CH02745	COG1683	Conserved Protein
AsACE_CH02746	COG3123	guanosine phosphorylase activity
AsACE_CH02748	COG2837	iron assimilation
AsACE_CH02751	COG3501	Rhs element vgr protein
AsACE_CH02752	COG0436	Aminotransferase
AsACE_CH02753	COG0534	Mate efflux family protein
AsACE_CH02763	COG3706	GGDEF domain
AsACE_CH02764	COG0745	RESPONSE REGULATOR receiver
AsACE_CH02764	COG3706	GGDEF domain
AsACE_CH02765	COG1715	Restriction endonuclease
AsACE_CH02766	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AsACE_CH02766	COG0519	Catalyzes the synthesis of GMP from XMP
AsACE_CH02768	COG2259	Doxx family
AsACE_CH02769	COG0586	Pfam SNARE associated Golgi protein
AsACE_CH02772	COG1192	Involved in chromosome partitioning
AsACE_CH02781	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AsACE_CH02782	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AsACE_CH02783	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AsACE_CH02785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AsACE_CH02786	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AsACE_CH02787	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AsACE_CH02790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AsACE_CH02791	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AsACE_CH02794	COG0110	maltose O-acetyltransferase activity
AsACE_CH02795	COG0463	Glycosyl transferase, family 2
AsACE_CH02795	COG1216	Glycosyl transferase, family 2
AsACE_CH02799	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AsACE_CH02803	COG1091	dTDP-4-dehydrorhamnose reductase activity
AsACE_CH02806	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AsACE_CH02808	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AsACE_CH02809	COG0438	transferase activity, transferring glycosyl groups
AsACE_CH02810	COG0438	transferase activity, transferring glycosyl groups
AsACE_CH02811	COG0438	transferase activity, transferring glycosyl groups
AsACE_CH02816	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AsACE_CH02819	COG0545	Peptidyl-prolyl cis-trans isomerase
AsACE_CH02822	COG1194	a g-specific adenine glycosylase
AsACE_CH02825	COG2818	Glycosylase
AsACE_CH02826	COG1064	alcohol dehydrogenase
AsACE_CH02827	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AsACE_CH02831	COG0783	Belongs to the Dps family
AsACE_CH02835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AsACE_CH02838	COG2233	PERMEase
AsACE_CH02839	COG0583	DNA-binding transcription factor activity
AsACE_CH02843	COG0129	dihydroxy-acid dehydratase activity
AsACE_CH02847	COG0428	transporter
AsACE_CH02848	COG0733	neurotransmitter:sodium symporter activity
AsACE_CH02849	COG1012	belongs to the aldehyde dehydrogenase family
AsACE_CH02851	COG0693	protein deglycase activity
AsACE_CH02854	COG2814	Major facilitator Superfamily
AsACE_CH02862	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AsACE_CH02863	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AsACE_CH02864	COG2951	lytic endotransglycosylase activity
AsACE_CH02865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AsACE_CH02869	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AsACE_CH02874	COG2388	GCN5-related N-acetyl-transferase
AsACE_CH02875	COG2814	Major facilitator Superfamily
AsACE_CH02876	COG0861	Integral membrane protein TerC family
AsACE_CH02877	COG0402	S-adenosylhomocysteine deaminase activity
AsACE_CH02880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AsACE_CH02885	COG0706	membrane insertase activity
AsACE_CH02886	COG0594	ribonuclease P activity
AsACE_CH02887	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AsACE_p100009	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AsACE_p100010	COG4774	siderophore transport
AsACE_p100015	COG1454	alcohol dehydrogenase
AsACE_p100024	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AsACE_p100029	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AsACE_p100029	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AsACE_p100030	COG1105	Belongs to the carbohydrate kinase PfkB family
AsACE_p100031	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AsACE_p100031	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AsACE_p100031	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AsACE_p100033	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AsACE_p100037	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AsACE_p100038	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AsACE_p100039	COG0022	dehydrogenase e1 component
AsACE_p100040	COG0508	dehydrogenase complex catalyzes the overall conversion of
AsACE_p100043	COG1063	alcohol dehydrogenase
AsACE_p100044	COG2801	Transposase and inactivated derivatives
AsACE_p100049	COG2132	Multicopper oxidase
AsACE_p100052	COG3316	Transposase and inactivated derivatives
AsACE_p100065	COG3316	Transposase and inactivated derivatives
AsACE_p100067	COG3316	Transposase and inactivated derivatives
AsACE_p100068	COG0431	NADPH-dependent FMN reductase
AsACE_p100070	COG2132	Multicopper oxidase
AsACE_p100073	COG2205	protein histidine kinase activity
AsACE_p100074	COG3174	membrane
AsACE_p100075	COG2217	Heavy metal translocating P-type atpase
AsACE_p100087	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AsACE_p100088	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AsACE_p100090	COG1846	Transcriptional regulator
AsACE_p100091	COG1764	response to oxidative stress
AsACE_p100092	COG0753	catalase activity
AsACE_p100093	COG2801	Transposase and inactivated derivatives
AsACE_p100094	COG0583	DNA-binding transcription factor activity
AsACE_p100095	COG0730	response to heat
AsACE_p100096	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AsACE_p100097	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AsACE_p100100	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AsACE_p100108	COG0579	oxidoreductase
AsACE_p100113	COG2130	NADP-dependent
AsACE_p100114	COG1309	transcriptional regulator
AsACE_p100116	COG1902	pentaerythritol trinitrate reductase activity
AsACE_p100118	COG1979	alcohol dehydrogenase
AsACE_p100120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AsACE_p100124	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AsACE_p100125	COG0583	DNA-binding transcription factor activity
AsACE_p100126	COG4221	oxidoreductase activity
AsACE_p100130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AsACE_p100137	COG0642	Histidine kinase
AsACE_p100140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AsACE_p100144	COG3040	lipid binding
AsACE_p100146	COG3046	protein related to deoxyribodipyrimidine photolyase
AsACE_p100148	COG2351	hydroxyisourate hydrolase activity
AsACE_p100150	COG1373	ATPase (AAA superfamily
AsACE_p100157	COG0604	alcohol dehydrogenase
AsACE_p100158	COG1309	transcriptional regulator
AsACE_p100159	COG0583	DNA-binding transcription factor activity
AsACE_p100160	COG1380	Effector of murein hydrolase LrgA
AsACE_p100161	COG1346	cytolysis
AsACE_p100167	COG1192	Involved in chromosome partitioning
AsACE_p200008	COG4644	lycopene metabolic process
AsACE_p200009	COG3316	Transposase and inactivated derivatives
AsACE_p200012	COG3316	Transposase and inactivated derivatives
AsACE_p200014	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AsACE_p200021	COG1192	Involved in chromosome partitioning
AsACE_p200033	COG0741	lytic transglycosylase activity
AsACE_p200033	COG0739	heme binding
AsACE_p200033	COG1196	nuclear chromosome segregation
AsACE_p200036	COG1196	nuclear chromosome segregation
AsACE_p200036	COG0741	lytic transglycosylase activity
AsACE_p200036	COG0739	heme binding
AsACE_p200041	COG1525	nuclease
AsACE_p200048	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AsACE_p300003	COG3173	Aminoglycoside phosphotransferase
AsACE_p300009	COG3800	Transcriptional regulator
AsACE_p300009	COG1396	sequence-specific DNA binding
AsACE_p400007	COG2076	Multidrug Resistance protein
AsACE_p600003	COG3077	Addiction module antitoxin, RelB DinJ family
AsACE_p600006	COG5295	Hep Hag repeat protein