locus-tag	class	description
FSC12_00025	COG0864	Transcriptional regulator
FSC12_00060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC12_00065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC12_00070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC12_00070	COG1116	anion transmembrane transporter activity
FSC12_00080	COG2223	nitrite transmembrane transporter activity
FSC12_00085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC12_00090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC12_00095	COG0243	molybdopterin cofactor binding
FSC12_00105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSC12_00115	COG0314	molybdopterin synthase activity
FSC12_00120	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSC12_00120	COG0315	cyclic pyranopterin monophosphate synthase activity
FSC12_00125	COG0303	'Molybdopterin
FSC12_00130	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSC12_00135	COG4149	molybdate abc transporter
FSC12_00140	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FSC12_00145	COG2223	nitrite transmembrane transporter activity
FSC12_00155	COG0347	Belongs to the P(II) protein family
FSC12_00175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC12_00180	COG1309	transcriptional regulator
FSC12_00200	COG1944	ATP diphosphatase activity
FSC12_00215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC12_00230	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FSC12_00235	COG1877	trehalose-phosphatase activity
FSC12_00245	COG0583	DNA-binding transcription factor activity
FSC12_00255	COG0583	DNA-binding transcription factor activity
FSC12_00300	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FSC12_00305	COG2116	formate transmembrane transporter activity
FSC12_00310	COG0515	serine threonine protein kinase
FSC12_00330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSC12_00335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC12_00350	COG2194	sulfuric ester hydrolase activity
FSC12_00355	COG0745	RESPONSE REGULATOR receiver
FSC12_00360	COG0642	Histidine kinase
FSC12_00375	COG4221	oxidoreductase activity
FSC12_00410	COG3550	peptidyl-serine autophosphorylation
FSC12_00500	COG0596	Alpha beta hydrolase
FSC12_00530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC12_00535	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FSC12_00560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FSC12_00575	COG0439	Biotin carboxylase
FSC12_00585	COG3706	GGDEF domain
FSC12_00625	COG1546	Belongs to the CinA family
FSC12_00625	COG1058	Belongs to the CinA family
FSC12_00635	COG0372	Belongs to the citrate synthase family
FSC12_00655	COG0477	Major facilitator Superfamily
FSC12_00670	COG0542	response to heat
FSC12_00675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSC12_00700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC12_00710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSC12_00715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSC12_00720	COG0569	domain protein
FSC12_00725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSC12_00745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSC12_00755	COG1585	Membrane protein implicated in regulation of membrane protease activity
FSC12_00775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC12_00780	COG0776	regulation of translation
FSC12_00805	COG0822	iron-sulfur transferase activity
FSC12_00810	COG0316	Belongs to the HesB IscA family
FSC12_00840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSC12_00850	COG1027	Aspartate ammonia-lyase
FSC12_00855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC12_00870	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC12_00870	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC12_00870	COG0506	proline dehydrogenase activity
FSC12_00890	COG3781	membrane
FSC12_00895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC12_00925	COG0697	spore germination
FSC12_00950	COG0424	maF-like protein
FSC12_00960	COG2850	peptidyl-arginine hydroxylation
FSC12_00965	COG0625	glutathione transferase activity
FSC12_00970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC12_00975	COG0702	epimerase
FSC12_00980	COG0268	Binds directly to 16S ribosomal RNA
FSC12_00995	COG1011	Hydrolase
FSC12_01000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSC12_01010	COG2137	regulation of response to DNA damage stimulus
FSC12_01025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC12_01030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSC12_01035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC12_01045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC12_01060	COG0575	Belongs to the CDS family
FSC12_01065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSC12_01085	COG3852	Histidine kinase
FSC12_01100	COG2814	Major facilitator Superfamily
FSC12_01105	COG0445	tRNA wobble uridine modification
FSC12_01135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FSC12_01140	COG0138	bifunctional purine biosynthesis protein purh
FSC12_01145	COG0151	Belongs to the GarS family
FSC12_01160	COG1464	Belongs to the NlpA lipoprotein family
FSC12_01165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC12_01170	COG2011	ABC-type metal ion transport system permease component
FSC12_01205	COG3706	GGDEF domain
FSC12_01205	COG4251	negative regulation of phosphorylation
FSC12_01205	COG5001	Diguanylate cyclase
FSC12_01205	COG2203	Gaf domain
FSC12_01215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSC12_01225	COG4122	O-methyltransferase activity
FSC12_01230	COG0589	response to stress
FSC12_01255	COG1538	Outer membrane efflux protein
FSC12_01260	COG1137	ATPase activity
FSC12_01265	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FSC12_01275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FSC12_01280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSC12_01280	COG0517	IMP dehydrogenase activity
FSC12_01305	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_01320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC12_01320	COG0519	Catalyzes the synthesis of GMP from XMP
FSC12_01330	COG2353	YceI-like domain
FSC12_01345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSC12_01350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSC12_01360	COG2391	methyltransferase activity
FSC12_01445	COG1309	transcriptional regulator
FSC12_01520	COG0352	thiamine-phosphate diphosphorylase activity
FSC12_01535	COG3025	triphosphatase activity
FSC12_01555	COG3618	amidohydrolase
FSC12_01560	COG0612	Peptidase, M16
FSC12_01570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC12_01575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC12_01635	COG0515	serine threonine protein kinase
FSC12_01635	COG2815	serine threonine protein kinase
FSC12_01690	COG4783	chaperone-mediated protein folding
FSC12_01745	COG0778	Nitroreductase
FSC12_01755	COG0513	Belongs to the DEAD box helicase family
FSC12_01760	COG1278	Cold shock
FSC12_01775	COG2363	Small membrane protein
FSC12_01800	COG0625	glutathione transferase activity
FSC12_01805	COG0659	secondary active sulfate transmembrane transporter activity
FSC12_01810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSC12_01815	COG0582	viral genome integration into host DNA
FSC12_01875	COG3047	cAMP biosynthetic process
FSC12_01875	COG2885	chlorophyll binding
FSC12_01885	COG0540	Belongs to the ATCase OTCase family
FSC12_01905	COG0667	Aldo Keto reductase
FSC12_01915	COG1765	OsmC-like protein
FSC12_01920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC12_01945	COG1136	(ABC) transporter
FSC12_01950	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC12_01955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC12_01960	COG0281	malic enzyme
FSC12_01985	COG0714	Associated with various cellular activities
FSC12_01990	COG2879	small protein
FSC12_01995	COG1966	Carbon starvation protein
FSC12_02000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSC12_02040	COG1067	ATP-dependent peptidase activity
FSC12_02045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FSC12_02050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSC12_02055	COG0583	DNA-binding transcription factor activity
FSC12_02080	COG1686	Belongs to the peptidase S11 family
FSC12_02085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSC12_02100	COG2351	hydroxyisourate hydrolase activity
FSC12_02115	COG5002	protein histidine kinase activity
FSC12_02155	COG0616	signal peptide processing
FSC12_02165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSC12_02175	COG0573	inorganic phosphate transmembrane transporter activity
FSC12_02190	COG0076	glutamate decarboxylase activity
FSC12_02195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSC12_02205	COG0671	phosphoesterase, PA-phosphatase related
FSC12_02285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSC12_02295	COG2814	Major facilitator Superfamily
FSC12_02305	COG1733	regulation of RNA biosynthetic process
FSC12_02330	COG0556	nucleotide-excision repair
FSC12_02380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC12_02385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC12_02390	COG1960	acyl-CoA dehydrogenase activity
FSC12_02400	COG2084	Dehydrogenase
FSC12_02405	COG2233	PERMEase
FSC12_02410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC12_02415	COG0251	oxidation-reduction process
FSC12_02420	COG1335	isochorismatase
FSC12_02425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC12_02430	COG0596	Alpha beta hydrolase
FSC12_02440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC12_02450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSC12_02490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FSC12_02495	COG3161	chorismate lyase activity
FSC12_02505	COG0174	glutamine synthetase
FSC12_02510	COG0512	Glutamine amidotransferase of anthranilate synthase
FSC12_02515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSC12_02530	COG0302	gtp cyclohydrolase
FSC12_02545	COG3706	GGDEF domain
FSC12_02560	COG3739	integral membrane protein
FSC12_02585	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC12_02585	COG1902	pentaerythritol trinitrate reductase activity
FSC12_02595	COG0277	FAD linked oxidase domain protein
FSC12_02605	COG2186	Transcriptional regulator
FSC12_02610	COG1620	l-lactate permease
FSC12_02620	COG5001	Diguanylate cyclase
FSC12_02620	COG4251	negative regulation of phosphorylation
FSC12_02620	COG3706	GGDEF domain
FSC12_02620	COG2203	Gaf domain
FSC12_02625	COG0418	dihydroorotase activity
FSC12_02630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSC12_02640	COG4771	TonB-dependent receptor
FSC12_02650	COG0833	amino acid
FSC12_02690	COG4172	Belongs to the ABC transporter superfamily
FSC12_02695	COG4239	(ABC) transporter, permease
FSC12_02700	COG4174	ABC transporter (Permease)
FSC12_02705	COG4166	transmembrane transport
FSC12_02710	COG1388	LysM domain
FSC12_02710	COG0741	lytic transglycosylase activity
FSC12_02760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC12_02765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC12_02810	COG2155	Conserved Protein
FSC12_02825	COG0006	proline dipeptidase activity
FSC12_02860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSC12_02870	COG2234	aminopeptidase activity
FSC12_02880	COG3384	dioxygenase
FSC12_02890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSC12_02895	COG2878	Part of a membrane complex involved in electron transport
FSC12_02900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSC12_02925	COG0768	penicillin binding
FSC12_02930	COG0742	ribosomal rna small subunit methyltransferase
FSC12_03015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSC12_03035	COG3321	synthase
FSC12_03035	COG4221	oxidoreductase activity
FSC12_03035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC12_03035	COG0604	alcohol dehydrogenase
FSC12_03080	COG2268	Band 7 protein
FSC12_03085	COG1649	PFAM Uncharacterised BCR, COG1649
FSC12_03085	COG0726	polysaccharide deacetylase
FSC12_03095	COG1215	transferase activity, transferring glycosyl groups
FSC12_03100	COG1649	PFAM Uncharacterised BCR, COG1649
FSC12_03100	COG0726	polysaccharide deacetylase
FSC12_03110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSC12_03120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC12_03135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSC12_03140	COG1053	succinate dehydrogenase
FSC12_03145	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FSC12_03165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSC12_03165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC12_03200	COG2321	neutral zinc metallopeptidase
FSC12_03205	COG2354	Protein conserved in bacteria
FSC12_03225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSC12_03230	COG1773	rubredoxin
FSC12_03235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC12_03245	COG0583	DNA-binding transcription factor activity
FSC12_03255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC12_03265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FSC12_03270	COG4181	ATPase activity
FSC12_03295	COG0500	methyltransferase
FSC12_03300	COG4771	TonB-dependent receptor
FSC12_03320	COG0306	phosphate transporter
FSC12_03350	COG2376	Dihydroxyacetone kinase
FSC12_03355	COG2066	Belongs to the glutaminase family
FSC12_03360	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_03370	COG0525	valine-tRNA ligase activity
FSC12_03395	COG2323	membrane
FSC12_03400	COG0546	phosphoglycolate phosphatase activity
FSC12_03425	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC12_03440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC12_03450	COG0142	geranyltranstransferase activity
FSC12_03455	COG2828	Protein conserved in bacteria
FSC12_03460	COG1113	amino acid transport
FSC12_03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC12_03495	COG1530	ribonuclease E activity
FSC12_03500	COG0424	maF-like protein
FSC12_03505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FSC12_03510	COG1792	Involved in formation and maintenance of cell shape
FSC12_03515	COG1077	Cell shape determining protein MreB Mrl
FSC12_03520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC12_03530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC12_03545	COG0471	metal ion transport
FSC12_03560	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FSC12_03575	COG1294	oxidase, subunit
FSC12_03580	COG1271	oxidase subunit
FSC12_03600	COG4106	trans-aconitate 2-methyltransferase activity
FSC12_03615	COG0596	Alpha beta hydrolase
FSC12_03620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FSC12_03640	COG1113	amino acid transport
FSC12_03645	COG1448	Aminotransferase
FSC12_03660	COG0625	glutathione transferase activity
FSC12_03675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC12_03695	COG4716	Myosin-crossreactive antigen
FSC12_03770	COG1785	Belongs to the alkaline phosphatase family
FSC12_03775	COG1785	Belongs to the alkaline phosphatase family
FSC12_03800	COG1215	transferase activity, transferring glycosyl groups
FSC12_03815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FSC12_03870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSC12_03875	COG2050	protein possibly involved in aromatic compounds catabolism
FSC12_03885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSC12_03900	COG0420	3'-5' exonuclease activity
FSC12_03930	COG0735	belongs to the Fur family
FSC12_03935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC12_03940	COG2914	Belongs to the UPF0125 (RnfH) family
FSC12_03955	COG0121	glutamine amidotransferase
FSC12_03965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC12_03970	COG0756	dUTP diphosphatase activity
FSC12_03980	COG2885	chlorophyll binding
FSC12_03985	COG0204	Acyl-transferase
FSC12_04015	COG1674	ftsk spoiiie
FSC12_04015	COG0531	amino acid
FSC12_04020	COG0492	ferredoxin-NADP+ reductase activity
FSC12_04025	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSC12_04035	COG0456	acetyltransferase
FSC12_04045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSC12_04050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSC12_04060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSC12_04080	COG1113	amino acid transport
FSC12_04085	COG0251	oxidation-reduction process
FSC12_04105	COG1652	LysM domain
FSC12_04110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSC12_04115	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_04130	COG1399	metal-binding, possibly nucleic acid-binding protein
FSC12_04135	COG3101	peptidyl-lysine hydroxylation
FSC12_04140	COG0009	L-threonylcarbamoyladenylate synthase
FSC12_04160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSC12_04165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSC12_04180	COG2193	ferroxidase activity
FSC12_04185	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FSC12_04190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSC12_04200	COG1196	nuclear chromosome segregation
FSC12_04210	COG0730	response to heat
FSC12_04215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FSC12_04215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FSC12_04225	COG3545	Serine hydrolase
FSC12_04230	COG3545	Serine hydrolase
FSC12_04235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSC12_04260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSC12_04270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSC12_04285	COG4269	membrane
FSC12_04305	COG1968	undecaprenyl-diphosphatase activity
FSC12_04310	COG1214	PFAM Peptidase M22, glycoprotease
FSC12_04320	COG0494	nUDIX hydrolase
FSC12_04335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSC12_04360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC12_04365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC12_04370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FSC12_04375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSC12_04380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSC12_04385	COG0625	glutathione transferase activity
FSC12_04390	COG2969	positive regulation of protein catabolic process
FSC12_04440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC12_04445	COG1764	response to oxidative stress
FSC12_04495	COG0037	tRNA processing
FSC12_04505	COG0248	Ppx GppA phosphatase
FSC12_04530	COG0072	phenylalanine-tRNA ligase activity
FSC12_04535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSC12_04565	COG1238	metal cluster binding
FSC12_04575	COG0625	glutathione transferase activity
FSC12_04590	COG0546	phosphoglycolate phosphatase activity
FSC12_04630	COG0318	PFAM AMP-dependent synthetase and ligase
FSC12_04655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSC12_04670	COG1216	Glycosyl transferase, family 2
FSC12_04695	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSC12_04745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSC12_04765	COG1660	Displays ATPase and GTPase activities
FSC12_04780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSC12_04785	COG0617	tRNA 3'-terminal CCA addition
FSC12_04790	COG1555	photosystem II stabilization
FSC12_04795	COG3956	TIGRFAM MazG family protein
FSC12_04800	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_04815	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC12_04825	COG0124	histidyl-tRNA synthetase
FSC12_04835	COG1426	Protein conserved in bacteria
FSC12_04855	COG2975	iron-sulfur cluster assembly
FSC12_04890	COG0440	acetolactate synthase activity
FSC12_04895	COG0028	Belongs to the TPP enzyme family
FSC12_04920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC12_04925	COG1136	(ABC) transporter
FSC12_04925	COG0577	efflux transmembrane transporter activity
FSC12_04930	COG1538	Outer membrane efflux protein
FSC12_04940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FSC12_04950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSC12_04955	COG1162	GTPase activity
FSC12_04985	COG0084	hydrolase, TatD family'
FSC12_05000	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSC12_05025	COG0793	Belongs to the peptidase S41A family
FSC12_05050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSC12_05055	COG0857	belongs to the CobB CobQ family
FSC12_05055	COG0280	phosphate acetyltransferase
FSC12_05060	COG2610	gluconate transmembrane transporter activity
FSC12_05065	COG1454	alcohol dehydrogenase
FSC12_05075	COG1414	Transcriptional regulator
FSC12_05085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC12_05085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC12_05105	COG0740	serine-type endopeptidase activity
FSC12_05115	COG4771	TonB-dependent receptor
FSC12_05120	COG4774	siderophore transport
FSC12_05125	COG4774	siderophore transport
FSC12_05130	COG3128	pkhd-type hydroxylase
FSC12_05155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSC12_05165	COG2813	Specifically methylates the guanine in position
FSC12_05165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC12_05215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FSC12_05230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FSC12_05240	COG0411	ABC transporter
FSC12_05260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC12_05270	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_05280	COG4638	Rieske (2fe-2S)
FSC12_05300	COG0154	amidase activity
FSC12_05310	COG0583	DNA-binding transcription factor activity
FSC12_05315	COG4948	Mandelate Racemase Muconate Lactonizing
FSC12_05320	COG4829	muconolactone delta-isomerase
FSC12_05335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC12_05340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC12_05345	COG0183	Belongs to the thiolase family
FSC12_05350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC12_05360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FSC12_05400	COG0788	formyltetrahydrofolate deformylase activity
FSC12_05425	COG4651	solute:proton antiporter activity
FSC12_05425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSC12_05445	COG0724	RNA recognition motif
FSC12_05450	COG0210	DNA helicase
FSC12_05455	COG1929	Belongs to the glycerate kinase type-1 family
FSC12_05490	COG2900	Belongs to the SlyX family
FSC12_05500	COG1560	Kdo2-lipid A biosynthetic process
FSC12_05545	COG0252	asparaginase activity
FSC12_05575	COG0473	3-isopropylmalate dehydrogenase activity
FSC12_05590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSC12_05645	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FSC12_05655	COG0519	Catalyzes the synthesis of GMP from XMP
FSC12_05670	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC12_05675	COG3384	dioxygenase
FSC12_05680	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_05695	COG4638	Rieske (2fe-2S)
FSC12_05700	COG0583	DNA-binding transcription factor activity
FSC12_05730	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSC12_05735	COG3971	2-oxopent-4-enoate hydratase activity
FSC12_05740	COG0546	phosphoglycolate phosphatase activity
FSC12_05755	COG1530	ribonuclease E activity
FSC12_05760	COG0318	PFAM AMP-dependent synthetase and ligase
FSC12_05785	COG1983	PspC domain protein
FSC12_05795	COG0471	metal ion transport
FSC12_05815	COG0751	glycine-tRNA ligase activity
FSC12_05850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC12_05880	COG0493	'glutamate synthase
FSC12_05890	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FSC12_05905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC12_05920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSC12_05930	COG0644	oxidoreductase
FSC12_05930	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSC12_05945	COG3501	Rhs element vgr protein
FSC12_05955	COG4535	Mg2 and Co2 transporter CorC
FSC12_05960	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSC12_05980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSC12_05990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSC12_06005	COG0789	Transcriptional regulator
FSC12_06010	COG2841	Protein conserved in bacteria
FSC12_06015	COG1185	polyribonucleotide nucleotidyltransferase activity
FSC12_06020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSC12_06030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC12_06035	COG1074	ATP-dependent DNA helicase activity
FSC12_06040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSC12_06075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC12_06095	COG0745	RESPONSE REGULATOR receiver
FSC12_06100	COG2205	protein histidine kinase activity
FSC12_06105	COG0427	acetyl-CoA hydrolase
FSC12_06115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSC12_06145	COG0326	Molecular chaperone. Has ATPase activity
FSC12_06160	COG2056	Na+-H+ antiporter family
FSC12_06190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSC12_06195	COG0085	RNA polymerase activity
FSC12_06210	COG0081	regulation of translation
FSC12_06215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSC12_06235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSC12_06265	COG0546	phosphoglycolate phosphatase activity
FSC12_06295	COG0824	Thioesterase
FSC12_06315	COG0181	hydroxymethylbilane synthase activity
FSC12_06325	COG3275	phosphorelay sensor kinase activity
FSC12_06345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSC12_06355	COG0322	excinuclease ABC activity
FSC12_06370	COG3706	GGDEF domain
FSC12_06375	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC12_06375	COG1024	Enoyl-CoA hydratase
FSC12_06435	COG0131	Imidazoleglycerol-phosphate dehydratase
FSC12_06440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSC12_06485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FSC12_06490	COG0107	imidazoleglycerol-phosphate synthase activity
FSC12_06520	COG3158	transport of potassium into the cell
FSC12_06550	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FSC12_06580	COG2814	Major facilitator Superfamily
FSC12_06590	COG0351	phosphomethylpyrimidine kinase
FSC12_06590	COG0352	thiamine-phosphate diphosphorylase activity
FSC12_06590	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC12_06595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSC12_06600	COG3706	GGDEF domain
FSC12_06630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC12_06635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC12_06640	COG3162	membrane
FSC12_06645	COG0784	Response regulator, receiver
FSC12_06645	COG2205	protein histidine kinase activity
FSC12_06670	COG0307	riboflavin synthase, alpha
FSC12_06685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC12_06695	COG0668	transmembrane transport
FSC12_06700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC12_06705	COG1519	Transferase
FSC12_06710	COG1902	pentaerythritol trinitrate reductase activity
FSC12_06715	COG0640	Transcriptional regulator
FSC12_06735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSC12_06745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC12_06760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC12_06760	COG0426	domain, Protein
FSC12_06765	COG2119	membrane
FSC12_06800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSC12_06810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FSC12_06825	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSC12_06835	COG0189	ligase activity
FSC12_06850	COG2132	Multicopper oxidase
FSC12_06870	COG3385	transposase activity
FSC12_06880	COG0708	Exodeoxyribonuclease III
FSC12_06885	COG1393	Belongs to the ArsC family
FSC12_06935	COG2351	hydroxyisourate hydrolase activity
FSC12_06940	COG2233	PERMEase
FSC12_06955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC12_06960	COG4266	Belongs to the allantoicase family
FSC12_06985	COG0784	Response regulator, receiver
FSC12_06985	COG2205	protein histidine kinase activity
FSC12_07010	COG0410	ABC transporter
FSC12_07040	COG3150	esterase
FSC12_07055	COG2918	glutathione biosynthetic process
FSC12_07070	COG2733	membrane
FSC12_07110	COG0753	catalase activity
FSC12_07130	COG3830	Belongs to the UPF0237 family
FSC12_07130	COG0560	Phosphoserine phosphatase
FSC12_07140	COG0385	Bile acid
FSC12_07145	COG1335	isochorismatase
FSC12_07150	COG2814	Major facilitator Superfamily
FSC12_07155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSC12_07165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSC12_07180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSC12_07185	COG3300	MHYT domain
FSC12_07185	COG5001	Diguanylate cyclase
FSC12_07190	COG2983	Belongs to the UPF0260 family
FSC12_07195	COG5487	UPF0391 membrane protein
FSC12_07200	COG0728	peptidoglycan biosynthetic process
FSC12_07205	COG3023	N-Acetylmuramoyl-L-alanine amidase
FSC12_07215	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSC12_07220	COG1309	transcriptional regulator
FSC12_07225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC12_07230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC12_07235	COG0546	phosphoglycolate phosphatase activity
FSC12_07240	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_07260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSC12_07260	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FSC12_07265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC12_07270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC12_07275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC12_07280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC12_07285	COG1116	anion transmembrane transporter activity
FSC12_07290	COG1309	transcriptional regulator
FSC12_07300	COG0196	riboflavin kinase activity
FSC12_07305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSC12_07315	COG1047	Peptidyl-prolyl cis-trans
FSC12_07325	COG2133	pyrroloquinoline quinone binding
FSC12_07355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSC12_07420	COG0488	(ABC) transporter
FSC12_07425	COG1063	alcohol dehydrogenase
FSC12_07435	COG0187	DNA topoisomerase II activity
FSC12_07445	COG0592	DNA-directed DNA polymerase activity
FSC12_07460	COG0594	ribonuclease P activity
FSC12_07465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSC12_07470	COG0706	membrane insertase activity
FSC12_07510	COG0402	S-adenosylhomocysteine deaminase activity
FSC12_07515	COG0861	Integral membrane protein TerC family
FSC12_07520	COG2814	Major facilitator Superfamily
FSC12_07525	COG2388	GCN5-related N-acetyl-transferase
FSC12_07550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC12_07565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSC12_07570	COG2951	lytic endotransglycosylase activity
FSC12_07575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FSC12_07580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSC12_07620	COG2814	Major facilitator Superfamily
FSC12_07635	COG0693	protein deglycase activity
FSC12_07645	COG1012	belongs to the aldehyde dehydrogenase family
FSC12_07650	COG0733	neurotransmitter:sodium symporter activity
FSC12_07660	COG0428	transporter
FSC12_07690	COG0129	dihydroxy-acid dehydratase activity
FSC12_07710	COG0583	DNA-binding transcription factor activity
FSC12_07715	COG2233	PERMEase
FSC12_07730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC12_07755	COG0783	Belongs to the Dps family
FSC12_07770	COG2814	Major facilitator Superfamily
FSC12_07775	COG0656	L-ascorbic acid biosynthetic process
FSC12_07780	COG0583	DNA-binding transcription factor activity
FSC12_07785	COG1064	alcohol dehydrogenase
FSC12_07790	COG2818	Glycosylase
FSC12_07805	COG1194	a g-specific adenine glycosylase
FSC12_07820	COG0545	Peptidyl-prolyl cis-trans isomerase
FSC12_07835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FSC12_07860	COG0438	transferase activity, transferring glycosyl groups
FSC12_07865	COG0438	transferase activity, transferring glycosyl groups
FSC12_07870	COG0438	transferase activity, transferring glycosyl groups
FSC12_07875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC12_07885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSC12_07900	COG1216	Glycosyl transferase, family 2
FSC12_07905	COG0438	transferase activity, transferring glycosyl groups
FSC12_07915	COG0438	transferase activity, transferring glycosyl groups
FSC12_07925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC12_07930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSC12_07945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC12_07950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC12_07955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSC12_07965	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FSC12_07970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FSC12_07975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSC12_08020	COG2963	transposase activity
FSC12_08090	COG2801	Transposase and inactivated derivatives
FSC12_08095	COG3077	Addiction module antitoxin, RelB DinJ family
FSC12_08130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FSC12_08140	COG1570	exodeoxyribonuclease VII activity
FSC12_08210	COG3586	endonuclease activity
FSC12_08230	COG3756	Protein conserved in bacteria
FSC12_08265	COG0271	Belongs to the BolA IbaG family
FSC12_08290	COG0586	Pfam SNARE associated Golgi protein
FSC12_08295	COG2259	Doxx family
FSC12_08305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC12_08305	COG0519	Catalyzes the synthesis of GMP from XMP
FSC12_08315	COG3706	GGDEF domain
FSC12_08320	COG3706	GGDEF domain
FSC12_08365	COG0534	Mate efflux family protein
FSC12_08370	COG0436	Aminotransferase
FSC12_08375	COG3501	Rhs element vgr protein
FSC12_08390	COG2837	iron assimilation
FSC12_08400	COG3123	guanosine phosphorylase activity
FSC12_08410	COG1683	Conserved Protein
FSC12_08415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSC12_08420	COG1121	(ABC) transporter
FSC12_08470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSC12_08480	COG1012	belongs to the aldehyde dehydrogenase family
FSC12_08500	COG0697	spore germination
FSC12_08515	COG0758	DNA mediated transformation
FSC12_08570	COG2814	Major facilitator Superfamily
FSC12_08590	COG0477	Major facilitator Superfamily
FSC12_08595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC12_08635	COG1253	flavin adenine dinucleotide binding
FSC12_08645	COG2860	membrane
FSC12_08650	COG0477	Major facilitator Superfamily
FSC12_08660	COG0318	PFAM AMP-dependent synthetase and ligase
FSC12_08680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSC12_08705	COG0606	chelatase, subunit chli
FSC12_08715	COG0347	Belongs to the P(II) protein family
FSC12_08720	COG0004	ammonium transporteR
FSC12_08730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC12_08730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC12_08745	COG0586	Pfam SNARE associated Golgi protein
FSC12_08765	COG0795	lipopolysaccharide-transporting ATPase activity
FSC12_08770	COG0795	lipopolysaccharide-transporting ATPase activity
FSC12_08775	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSC12_08780	COG0793	Belongs to the peptidase S41A family
FSC12_08790	COG5002	protein histidine kinase activity
FSC12_08795	COG2197	response regulator
FSC12_08805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSC12_08815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC12_08820	COG4974	Belongs to the 'phage' integrase family
FSC12_08845	COG0772	Belongs to the SEDS family
FSC12_08855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC12_08860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSC12_08865	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSC12_08870	COG0494	nUDIX hydrolase
FSC12_08875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FSC12_08885	COG1538	Outer membrane efflux protein
FSC12_08900	COG1132	(ABC) transporter
FSC12_08910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSC12_08920	COG0497	DNA recombination
FSC12_08925	COG3123	guanosine phosphorylase activity
FSC12_08930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC12_08940	COG0237	dephospho-CoA kinase activity
FSC12_08995	COG0779	Required for maturation of 30S ribosomal subunits
FSC12_09000	COG0195	Participates in both transcription termination and antitermination
FSC12_09005	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSC12_09010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSC12_09020	COG2212	antiporter activity
FSC12_09025	COG1863	multisubunit Na H antiporter MnhE subunit
FSC12_09030	COG0651	ATP synthesis coupled electron transport
FSC12_09035	COG1006	Multisubunit Na H antiporter MnhC subunit
FSC12_09040	COG2111	Na H antiporter
FSC12_09040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC12_09055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSC12_09060	COG4221	oxidoreductase activity
FSC12_09070	COG0488	(ABC) transporter
FSC12_09110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC12_09130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSC12_09135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSC12_09145	COG2226	methyltransferase
FSC12_09195	COG0069	glutamate synthase activity
FSC12_09195	COG0070	glutamate synthase
FSC12_09195	COG0067	glutamate synthase
FSC12_09200	COG0493	'glutamate synthase
FSC12_09205	COG1704	LemA family
FSC12_09220	COG4969	Belongs to the N-Me-Phe pilin family
FSC12_09230	COG3307	-O-antigen
FSC12_09250	COG0675	Transposase, IS605 OrfB family
FSC12_09255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC12_09260	COG1758	RNA polymerase activity
FSC12_09265	COG0194	GDP metabolic process
FSC12_09275	COG4969	Belongs to the N-Me-Phe pilin family
FSC12_09310	COG0228	four-way junction DNA binding
FSC12_09315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSC12_09325	COG0335	large ribosomal subunit rRNA binding
FSC12_09335	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC12_09345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC12_09350	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC12_09355	COG5380	lipid catabolic process
FSC12_09360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSC12_09385	COG5006	permease, DMT superfamily
FSC12_09390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSC12_09395	COG0277	FAD linked oxidase domain protein
FSC12_09410	COG2814	Major facilitator Superfamily
FSC12_09420	COG0628	permease
FSC12_09440	COG2226	methyltransferase
FSC12_09455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSC12_09460	COG0254	rRNA binding
FSC12_09465	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC12_09480	COG0534	Mate efflux family protein
FSC12_09490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC12_09510	COG1278	Cold shock
FSC12_09515	COG1960	acyl-CoA dehydrogenase activity
FSC12_09530	COG0408	coproporphyrinogen oxidase activity
FSC12_09535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC12_09560	COG1127	ABC transporter
FSC12_09565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSC12_09570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSC12_09575	COG2854	intermembrane phospholipid transfer
FSC12_09585	COG0598	Magnesium transport protein CorA
FSC12_09595	COG0494	nUDIX hydrolase
FSC12_09600	COG1040	competence protein
FSC12_09605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSC12_09615	COG2937	Belongs to the GPAT DAPAT family
FSC12_09620	COG1946	Acyl-CoA thioesterase
FSC12_09625	COG1301	dicarboxylic acid transport
FSC12_09645	COG1959	2 iron, 2 sulfur cluster binding
FSC12_09655	COG0433	COG0433 Predicted ATPase
FSC12_09660	COG0626	cystathionine gamma-synthase activity
FSC12_09680	COG0088	Forms part of the polypeptide exit tunnel
FSC12_09685	COG0089	rRNA binding
FSC12_09695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FSC12_09745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSC12_09750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSC12_09760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSC12_09785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSC12_09795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSC12_09800	COG0202	RNA polymerase activity
FSC12_09805	COG0203	ribosomal protein L17
FSC12_09810	COG2072	flavoprotein involved in K transport
FSC12_09820	COG1960	acyl-CoA dehydrogenase activity
FSC12_09825	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FSC12_09860	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FSC12_09865	COG0339	signal peptide processing
FSC12_09890	COG0557	exoribonuclease II activity
FSC12_09925	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSC12_09930	COG2169	Transcriptional regulator
FSC12_09940	COG1295	ribonuclease BN
FSC12_10005	COG1702	phosphate starvation-inducible protein PhoH
FSC12_10010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSC12_10015	COG0741	lytic transglycosylase activity
FSC12_10015	COG0739	heme binding
FSC12_10015	COG1196	nuclear chromosome segregation
FSC12_10055	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FSC12_10060	COG1183	phosphatidylcholine synthase activity
FSC12_10095	COG1283	sodium-dependent phosphate transmembrane transporter activity
FSC12_10125	COG1607	acyl-coa hydrolase
FSC12_10155	COG2350	Protein conserved in bacteria
FSC12_10175	COG3781	membrane
FSC12_10180	COG2003	Belongs to the UPF0758 family
FSC12_10185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSC12_10195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSC12_10205	COG2814	Major facilitator Superfamily
FSC12_10225	COG0004	ammonium transporteR
FSC12_10240	COG3622	Belongs to the hyi family
FSC12_10245	COG2084	Dehydrogenase
FSC12_10250	COG1024	Enoyl-CoA hydratase
FSC12_10255	COG5002	protein histidine kinase activity
FSC12_10255	COG2205	protein histidine kinase activity
FSC12_10255	COG0784	Response regulator, receiver
FSC12_10260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC12_10275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC12_10285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSC12_10295	COG1862	Preprotein translocase
FSC12_10310	COG1704	LemA family
FSC12_10320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSC12_10350	COG1960	acyl-CoA dehydrogenase activity
FSC12_10355	COG1960	acyl-CoA dehydrogenase activity
FSC12_10365	COG2205	protein histidine kinase activity
FSC12_10370	COG0745	RESPONSE REGULATOR receiver
FSC12_10375	COG1113	amino acid transport
FSC12_10400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FSC12_10415	COG2096	Adenosyltransferase
FSC12_10420	COG4206	TonB-dependent receptor
FSC12_10460	COG0159	tryptophan synthase activity
FSC12_10470	COG0285	dihydrofolate synthase activity
FSC12_10485	COG0450	alkyl hydroperoxide reductase
FSC12_10500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSC12_10505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSC12_10575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSC12_10580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSC12_10625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC12_10630	COG1408	metallophosphoesterase
FSC12_10640	COG0477	Major facilitator Superfamily
FSC12_10645	COG1272	protein, Hemolysin III
FSC12_10670	COG1024	Enoyl-CoA hydratase
FSC12_10670	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC12_10675	COG0183	Belongs to the thiolase family
FSC12_10680	COG2207	Transcriptional regulator
FSC12_10690	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC12_10705	COG0183	Belongs to the thiolase family
FSC12_10730	COG0833	amino acid
FSC12_10740	COG2233	PERMEase
FSC12_10755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC12_10770	COG1902	pentaerythritol trinitrate reductase activity
FSC12_10790	COG0354	folic acid binding
FSC12_10795	COG2132	Multicopper oxidase
FSC12_10845	COG0564	pseudouridine synthase activity
FSC12_10860	COG2824	Alkylphosphonate utilization operon protein PhnA
FSC12_10875	COG0352	thiamine-phosphate diphosphorylase activity
FSC12_10875	COG0351	phosphomethylpyrimidine kinase
FSC12_10875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC12_10905	COG4772	TonB-dependent receptor
FSC12_10910	COG0431	NADPH-dependent FMN reductase
FSC12_10915	COG0798	PFAM Bile acid sodium symporter
FSC12_10920	COG0640	Transcriptional regulator
FSC12_10940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSC12_10945	COG1335	isochorismatase
FSC12_10955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC12_10960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC12_10960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FSC12_10965	COG0745	RESPONSE REGULATOR receiver
FSC12_10970	COG2205	protein histidine kinase activity
FSC12_10980	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC12_11000	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSC12_11015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC12_11025	COG0713	ATP synthesis coupled electron transport
FSC12_11030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC12_11065	COG0583	DNA-binding transcription factor activity
FSC12_11080	COG0531	amino acid
FSC12_11085	COG4303	Ethanolamine ammonia lyase large subunit
FSC12_11090	COG4302	ethanolamine ammonia-lyase activity
FSC12_11100	COG0668	transmembrane transport
FSC12_11105	COG2081	HI0933 family
FSC12_11115	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FSC12_11130	COG0004	ammonium transporteR
FSC12_11150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC12_11150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC12_11165	COG0489	protein tyrosine kinase activity
FSC12_11210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC12_11235	COG0840	transmembrane signaling receptor activity
FSC12_11325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSC12_11335	COG1289	transmembrane transporter activity
FSC12_11340	COG2814	Major facilitator Superfamily
FSC12_11350	COG0786	glutamate:sodium symporter activity
FSC12_11355	COG1115	amino acid carrier protein
FSC12_11365	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC12_11375	COG1607	acyl-coa hydrolase
FSC12_11385	COG2814	Major facilitator Superfamily
FSC12_11390	COG0583	DNA-binding transcription factor activity
FSC12_11410	COG0523	cobalamin synthesis protein
FSC12_11420	COG1285	pathogenesis
FSC12_11430	COG3706	GGDEF domain
FSC12_11430	COG4251	negative regulation of phosphorylation
FSC12_11430	COG5001	Diguanylate cyclase
FSC12_11430	COG2203	Gaf domain
FSC12_11465	COG0393	Putative heavy-metal-binding
FSC12_11470	COG0393	Putative heavy-metal-binding
FSC12_11475	COG1538	Outer membrane efflux protein
FSC12_11485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC12_11500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSC12_11510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FSC12_11525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSC12_11530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSC12_11530	COG1648	precorrin-2 dehydrogenase activity
FSC12_11535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FSC12_11545	COG0531	amino acid
FSC12_11560	COG0321	lipoyl(octanoyl) transferase activity
FSC12_11570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSC12_11595	COG0586	Pfam SNARE associated Golgi protein
FSC12_11620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSC12_11650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSC12_11680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FSC12_11690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FSC12_11695	COG0358	DNA primase activity
FSC12_11705	COG0564	pseudouridine synthase activity
FSC12_11720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSC12_11730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC12_11760	COG0251	oxidation-reduction process
FSC12_11765	COG1309	transcriptional regulator
FSC12_11775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSC12_11780	COG0505	Belongs to the CarA family
FSC12_11805	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FSC12_11810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC12_11820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSC12_11855	COG1253	flavin adenine dinucleotide binding
FSC12_11875	COG2239	Acts as a magnesium transporter
FSC12_11885	COG0501	Belongs to the peptidase M48B family
FSC12_11890	COG1196	nuclear chromosome segregation
FSC12_11890	COG0739	heme binding
FSC12_11890	COG0741	lytic transglycosylase activity
FSC12_11895	COG0037	tRNA processing
FSC12_11905	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FSC12_11915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC12_11930	COG0583	DNA-binding transcription factor activity
FSC12_11935	COG1960	acyl-CoA dehydrogenase activity
FSC12_11940	COG2814	Major facilitator Superfamily
FSC12_11945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSC12_11955	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FSC12_11980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC12_11985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSC12_11990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSC12_11995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FSC12_12030	COG1115	amino acid carrier protein
FSC12_12035	COG1113	amino acid transport
FSC12_12045	COG0019	diaminopimelate decarboxylase activity
FSC12_12055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSC12_12070	COG1280	lysine exporter protein (LysE YggA)
FSC12_12110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC12_12135	COG1671	Belongs to the UPF0178 family
FSC12_12150	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC12_12155	COG1136	(ABC) transporter
FSC12_12160	COG2333	competence protein COMEC
FSC12_12160	COG0658	competence protein
FSC12_12180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSC12_12185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSC12_12190	COG0628	permease
FSC12_12195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC12_12225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC12_12245	COG0823	Involved in the tonB-independent uptake of proteins
FSC12_12265	COG0824	Thioesterase
FSC12_12275	COG1473	amidohydrolase
FSC12_12290	COG2255	four-way junction helicase activity
FSC12_12305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSC12_12305	COG0047	phosphoribosylformylglycinamidine synthase activity
FSC12_12320	COG0583	DNA-binding transcription factor activity
FSC12_12330	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FSC12_12335	COG0778	Nitroreductase
FSC12_12340	COG1024	Enoyl-CoA hydratase
FSC12_12345	COG1056	cytidyltransferase-related domain
FSC12_12345	COG1051	belongs to the nudix hydrolase family
FSC12_12350	COG2353	YceI-like domain
FSC12_12355	COG0583	DNA-binding transcription factor activity
FSC12_12360	COG1279	arginine transmembrane transporter activity
FSC12_12370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSC12_12380	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSC12_12385	COG0602	queuosine metabolic process
FSC12_12400	COG0583	DNA-binding transcription factor activity
FSC12_12405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSC12_12410	COG4208	sulfate ABC transporter
FSC12_12425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC12_12430	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC12_12440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSC12_12460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC12_12485	COG0571	ribonuclease III activity
FSC12_12490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSC12_12500	COG1381	Involved in DNA repair and RecF pathway recombination
FSC12_12505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSC12_12535	COG0436	Aminotransferase
FSC12_12540	COG0024	Methionine aminopeptidase
FSC12_12545	COG0052	Belongs to the universal ribosomal protein uS2 family
FSC12_12570	COG2951	lytic endotransglycosylase activity
FSC12_12585	COG0842	Transport permease protein
FSC12_12590	COG1131	(ABC) transporter
FSC12_12605	COG2814	Major facilitator Superfamily
FSC12_12660	COG1414	Transcriptional regulator
FSC12_12665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC12_12670	COG1414	Transcriptional regulator
FSC12_12675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC12_12680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC12_12685	COG0183	Belongs to the thiolase family
FSC12_12690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSC12_12695	COG0596	Alpha beta hydrolase
FSC12_12700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSC12_12705	COG3485	protocatechuate 3,4-dioxygenase
FSC12_12710	COG3485	protocatechuate 3,4-dioxygenase
FSC12_12740	COG1960	acyl-CoA dehydrogenase activity
FSC12_12750	COG1012	belongs to the aldehyde dehydrogenase family
FSC12_12755	COG1024	Enoyl-CoA hydratase
FSC12_12760	COG2814	Major facilitator Superfamily
FSC12_12775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC12_12800	COG1278	Cold shock
FSC12_12815	COG1380	Effector of murein hydrolase LrgA
FSC12_12820	COG0583	DNA-binding transcription factor activity
FSC12_12870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC12_12890	COG3634	alkyl hydroperoxide reductase activity
FSC12_12895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC12_12905	COG0789	Transcriptional regulator
FSC12_12920	COG1720	tRNA m6t6A37 methyltransferase activity
FSC12_12930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSC12_12940	COG0745	RESPONSE REGULATOR receiver
FSC12_12945	COG0642	Histidine kinase
FSC12_12955	COG0494	nUDIX hydrolase
FSC12_12965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC12_12970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSC12_12975	COG3139	Protein of unknown function (DUF1315)
FSC12_12985	COG1301	dicarboxylic acid transport
FSC12_12995	COG1960	acyl-CoA dehydrogenase activity
FSC12_13000	COG0693	protein deglycase activity
FSC12_13010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSC12_13015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSC12_13045	COG2252	PERMEase
FSC12_13050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSC12_13065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSC12_13075	COG0527	aspartate kinase activity
FSC12_13080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FSC12_13085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSC12_13110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSC12_13125	COG1047	Peptidyl-prolyl cis-trans
FSC12_13130	COG1252	NADH dehydrogenase
FSC12_13150	COG2351	hydroxyisourate hydrolase activity
FSC12_13170	COG2755	lipolytic protein G-D-S-L family
FSC12_13170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC12_13175	COG0436	Aminotransferase
FSC12_13180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSC12_13185	COG0386	Belongs to the glutathione peroxidase family
FSC12_13200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSC12_13220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FSC12_13240	COG0012	GTP binding
FSC12_13245	COG2011	ABC-type metal ion transport system permease component
FSC12_13250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC12_13255	COG1464	Belongs to the NlpA lipoprotein family
FSC12_13395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FSC12_13410	COG4638	Rieske (2fe-2S)
FSC12_13425	COG2814	Major facilitator Superfamily
FSC12_13445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC12_13450	COG2814	Major facilitator Superfamily
FSC12_13470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC12_13475	COG0183	Belongs to the thiolase family
FSC12_13480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC12_13485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC12_13495	COG4829	muconolactone delta-isomerase
FSC12_13500	COG4948	Mandelate Racemase Muconate Lactonizing
FSC12_13505	COG0583	DNA-binding transcription factor activity
FSC12_13560	COG1454	alcohol dehydrogenase
FSC12_13595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSC12_13595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSC12_13600	COG1254	Belongs to the acylphosphatase family
FSC12_13630	COG3634	alkyl hydroperoxide reductase activity
FSC12_13660	COG1643	Atp-dependent helicase
FSC12_13680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC12_13685	COG2707	UPF0756 membrane protein
FSC12_13705	COG0564	pseudouridine synthase activity
FSC12_13710	COG0802	atpase or kinase
FSC12_13715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSC12_13725	COG1923	regulation of RNA biosynthetic process
FSC12_13730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC12_13740	COG3178	'Phosphotransferase
FSC12_13745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSC12_13755	COG1192	Involved in chromosome partitioning
FSC12_13760	COG1475	DNA binding
FSC12_13765	COG0811	peptide transport
FSC12_13775	COG1132	(ABC) transporter
FSC12_13780	COG1663	tetraacyldisaccharide 4'-kinase activity
FSC12_13800	COG0084	hydrolase, TatD family'
FSC12_13835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSC12_13865	COG0776	regulation of translation
FSC12_13875	COG0284	orotidine-5'-phosphate decarboxylase activity
FSC12_13885	COG2431	L-lysine efflux transmembrane transporter activity
FSC12_13900	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSC12_13925	COG1253	flavin adenine dinucleotide binding
FSC12_13955	COG0308	aminopeptidase N
FSC12_13965	COG0589	response to stress
FSC12_13970	COG0589	response to stress
FSC12_13980	COG3135	benzoate transporter
FSC12_13990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSC12_14005	COG0183	Belongs to the thiolase family
FSC12_14030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSC12_14035	COG0824	Thioesterase
FSC12_14040	COG1454	alcohol dehydrogenase
FSC12_14045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSC12_14065	COG0069	glutamate synthase activity
FSC12_14075	COG2308	Evidence 4 Homologs of previously reported genes of
FSC12_14085	COG1305	Transglutaminase-like
FSC12_14100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSC12_14125	COG0360	Binds together with S18 to 16S ribosomal RNA
FSC12_14135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FSC12_14140	COG1845	cytochrome c oxidase, subunit III
FSC12_14145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSC12_14150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSC12_14175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC12_14195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSC12_14200	COG2890	protein-(glutamine-N5) methyltransferase activity
FSC12_14205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC12_14210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC12_14240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSC12_14265	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FSC12_14270	COG0477	Major facilitator Superfamily
FSC12_14275	COG0729	surface antigen
FSC12_14290	COG1570	exodeoxyribonuclease VII activity
FSC12_14320	COG0786	glutamate:sodium symporter activity
FSC12_14325	COG3300	MHYT domain
FSC12_14325	COG5001	Diguanylate cyclase
FSC12_14355	COG0024	Methionine aminopeptidase
FSC12_14360	COG0583	DNA-binding transcription factor activity
FSC12_14365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSC12_14380	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC12_14380	COG1902	pentaerythritol trinitrate reductase activity
FSC12_14410	COG0148	phosphopyruvate hydratase activity
FSC12_14415	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FSC12_14425	COG0772	Belongs to the SEDS family
FSC12_14445	COG4890	Cyd operon protein YbgT
FSC12_14450	COG1294	oxidase, subunit
FSC12_14500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSC12_14520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC12_14530	COG0133	tryptophan synthase activity
FSC12_14535	COG0517	IMP dehydrogenase activity
FSC12_14565	COG0612	Peptidase, M16
FSC12_14570	COG0552	protein localization to endoplasmic reticulum
FSC12_14635	COG1960	acyl-CoA dehydrogenase activity
FSC12_14640	COG1960	acyl-CoA dehydrogenase activity
FSC12_14695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC12_14700	COG0730	response to heat
FSC12_14705	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC12_14710	COG2207	Transcriptional regulator
FSC12_14715	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC12_14720	COG1960	acyl-CoA dehydrogenase activity
FSC12_14725	COG2169	Transcriptional regulator
FSC12_14745	COG1525	nuclease
FSC12_14810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC12_14815	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSC12_14825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC12_14840	COG2814	Major facilitator Superfamily
FSC12_14845	COG0509	glycine decarboxylation via glycine cleavage system
FSC12_14855	COG2030	dehydratase
FSC12_14860	COG1132	(ABC) transporter
FSC12_14865	COG0668	transmembrane transport
FSC12_14880	COG3122	Protein conserved in bacteria
FSC12_14885	COG3619	membrane
FSC12_14900	COG0640	Transcriptional regulator
FSC12_14905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC12_14915	COG0789	Transcriptional regulator
FSC12_14940	COG0830	nickel cation binding
FSC12_14950	COG0829	nickel cation binding
FSC12_14960	COG0831	urea catabolic process
FSC12_14970	COG0804	urea catabolic process
FSC12_15015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC12_15020	COG0183	Belongs to the thiolase family
FSC12_15025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC12_15030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC12_15035	COG3135	benzoate transporter
FSC12_15040	COG1028	Short-chain dehydrogenase reductase Sdr
FSC12_15045	COG0633	Ferredoxin
FSC12_15045	COG0543	2 iron, 2 sulfur cluster binding
FSC12_15050	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FSC12_15055	COG4638	Rieske (2fe-2S)
FSC12_15065	COG4829	muconolactone delta-isomerase
FSC12_15070	COG4948	Mandelate Racemase Muconate Lactonizing
FSC12_15075	COG0583	DNA-binding transcription factor activity
FSC12_15080	COG2814	Major facilitator Superfamily
FSC12_15090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSC12_15095	COG0318	PFAM AMP-dependent synthetase and ligase
FSC12_15115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC12_15120	COG0583	DNA-binding transcription factor activity
FSC12_15135	COG0439	Biotin carboxylase
FSC12_15195	COG0673	inositol 2-dehydrogenase activity
FSC12_15215	COG2826	transposase and inactivated derivatives, IS30 family
FSC12_15235	COG1660	Displays ATPase and GTPase activities
FSC12_15385	COG2963	transposase activity
FSC12_15455	COG4626	Terminase
FSC12_15455	COG1802	Transcriptional regulator
FSC12_15540	COG1192	Involved in chromosome partitioning
FSC12_15655	COG0582	viral genome integration into host DNA
FSC12_15670	COG1230	cation diffusion facilitator family transporter
FSC12_15705	COG1683	Conserved Protein
FSC12_15760	COG4974	Belongs to the 'phage' integrase family
FSC12_15785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC12_15860	COG1373	ATPase (AAA superfamily
FSC12_16005	COG3173	Aminoglycoside phosphotransferase
FSC12_16015	COG0488	(ABC) transporter
FSC12_16080	COG0583	DNA-binding transcription factor activity
FSC12_16115	COG3657	addiction module killer protein
FSC12_16120	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC12_16185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain