locus-tag	class	description
C0119_00115	COG1960	acyl-CoA dehydrogenase activity
C0119_00120	COG1960	acyl-CoA dehydrogenase activity
C0119_00200	COG0552	protein localization to endoplasmic reticulum
C0119_00235	COG0517	IMP dehydrogenase activity
C0119_00240	COG0133	tryptophan synthase activity
C0119_00250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0119_00270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C0119_00320	COG1294	oxidase, subunit
C0119_00325	COG4890	Cyd operon protein YbgT
C0119_00350	COG0772	Belongs to the SEDS family
C0119_00360	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C0119_00365	COG0148	phosphopyruvate hydratase activity
C0119_00395	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0119_00395	COG1902	pentaerythritol trinitrate reductase activity
C0119_00410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C0119_00415	COG0583	DNA-binding transcription factor activity
C0119_00420	COG0024	Methionine aminopeptidase
C0119_00425	COG1114	Component of the transport system for branched-chain amino acids
C0119_00445	COG0786	glutamate:sodium symporter activity
C0119_00460	COG2826	transposase and inactivated derivatives, IS30 family
C0119_00495	COG1570	exodeoxyribonuclease VII activity
C0119_00510	COG0729	surface antigen
C0119_00520	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
C0119_00545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0119_00570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0119_00580	COG2890	protein-(glutamine-N5) methyltransferase activity
C0119_00585	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C0119_00600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0119_00625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0119_00630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0119_00635	COG1845	cytochrome c oxidase, subunit III
C0119_00640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0119_00650	COG0360	Binds together with S18 to 16S ribosomal RNA
C0119_00665	COG0305	Participates in initiation and elongation during chromosome replication
C0119_00670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0119_00685	COG1305	Transglutaminase-like
C0119_00695	COG2308	Evidence 4 Homologs of previously reported genes of
C0119_00705	COG0069	glutamate synthase activity
C0119_00725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0119_00730	COG1454	alcohol dehydrogenase
C0119_00735	COG0824	Thioesterase
C0119_00765	COG0183	Belongs to the thiolase family
C0119_00780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0119_00790	COG3135	benzoate transporter
C0119_00800	COG0589	response to stress
C0119_00805	COG0589	response to stress
C0119_00815	COG0308	aminopeptidase N
C0119_00845	COG1253	flavin adenine dinucleotide binding
C0119_00875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C0119_00890	COG2431	L-lysine efflux transmembrane transporter activity
C0119_00910	COG0776	regulation of translation
C0119_00930	COG0590	tRNA wobble adenosine to inosine editing
C0119_00940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C0119_00975	COG0084	hydrolase, TatD family'
C0119_00995	COG1663	tetraacyldisaccharide 4'-kinase activity
C0119_01000	COG1132	(ABC) transporter
C0119_01010	COG0811	peptide transport
C0119_01015	COG1475	DNA binding
C0119_01020	COG1192	Involved in chromosome partitioning
C0119_01030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0119_01035	COG3178	'Phosphotransferase
C0119_01045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0119_01050	COG1923	regulation of RNA biosynthetic process
C0119_01060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C0119_01065	COG0802	atpase or kinase
C0119_01070	COG0564	pseudouridine synthase activity
C0119_01095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C0119_01120	COG0450	alkyl hydroperoxide reductase
C0119_01145	COG3634	alkyl hydroperoxide reductase activity
C0119_01175	COG1254	Belongs to the acylphosphatase family
C0119_01180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C0119_01180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C0119_01260	COG1464	Belongs to the NlpA lipoprotein family
C0119_01265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C0119_01270	COG2011	ABC-type metal ion transport system permease component
C0119_01275	COG0012	GTP binding
C0119_01295	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C0119_01310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C0119_01315	COG0436	Aminotransferase
C0119_01325	COG0386	Belongs to the glutathione peroxidase family
C0119_01330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0119_01335	COG0436	Aminotransferase
C0119_01340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0119_01340	COG2755	lipolytic protein G-D-S-L family
C0119_01360	COG2351	hydroxyisourate hydrolase activity
C0119_01385	COG1252	NADH dehydrogenase
C0119_01390	COG1047	Peptidyl-prolyl cis-trans
C0119_01405	COG0501	Belongs to the peptidase M48B family
C0119_01410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0119_01450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0119_01455	COG0527	aspartate kinase activity
C0119_01465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C0119_01480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C0119_01485	COG2252	PERMEase
C0119_01505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C0119_01510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0119_01520	COG0693	protein deglycase activity
C0119_01525	COG1960	acyl-CoA dehydrogenase activity
C0119_01530	COG1301	dicarboxylic acid transport
C0119_01540	COG3139	Protein of unknown function (DUF1315)
C0119_01545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0119_01550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0119_01560	COG0494	nUDIX hydrolase
C0119_01570	COG0642	Histidine kinase
C0119_01575	COG0745	RESPONSE REGULATOR receiver
C0119_01585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0119_01595	COG1720	tRNA m6t6A37 methyltransferase activity
C0119_01610	COG0789	Transcriptional regulator
C0119_01620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0119_01645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0119_01710	COG1278	Cold shock
C0119_01740	COG3177	Filamentation induced by cAMP protein fic
C0119_01750	COG0737	Belongs to the 5'-nucleotidase family
C0119_01770	COG0431	NADPH-dependent FMN reductase
C0119_01775	COG0798	PFAM Bile acid sodium symporter
C0119_01785	COG0640	Transcriptional regulator
C0119_01895	COG0582	viral genome integration into host DNA
C0119_01905	COG1131	(ABC) transporter
C0119_01910	COG0842	Transport permease protein
C0119_01925	COG2951	lytic endotransglycosylase activity
C0119_01950	COG0052	Belongs to the universal ribosomal protein uS2 family
C0119_01955	COG0024	Methionine aminopeptidase
C0119_01990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C0119_01995	COG1381	Involved in DNA repair and RecF pathway recombination
C0119_02005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C0119_02010	COG0571	ribonuclease III activity
C0119_02035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0119_02055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0119_02065	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0119_02070	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0119_02085	COG4208	sulfate ABC transporter
C0119_02090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0119_02095	COG0583	DNA-binding transcription factor activity
C0119_02115	COG0602	queuosine metabolic process
C0119_02120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C0119_02130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0119_02140	COG2353	YceI-like domain
C0119_02145	COG1051	belongs to the nudix hydrolase family
C0119_02145	COG1056	cytidyltransferase-related domain
C0119_02150	COG1024	Enoyl-CoA hydratase
C0119_02155	COG0778	Nitroreductase
C0119_02185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0119_02185	COG0047	phosphoribosylformylglycinamidine synthase activity
C0119_02200	COG2255	four-way junction helicase activity
C0119_02215	COG1473	amidohydrolase
C0119_02225	COG0824	Thioesterase
C0119_02245	COG0823	Involved in the tonB-independent uptake of proteins
C0119_02250	COG2885	chlorophyll binding
C0119_02265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0119_02305	COG0628	permease
C0119_02310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0119_02315	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0119_02335	COG2333	competence protein COMEC
C0119_02335	COG0658	competence protein
C0119_02340	COG1136	(ABC) transporter
C0119_02345	COG4591	ABC-type transport system involved in lipoprotein release permease component
C0119_02360	COG1671	Belongs to the UPF0178 family
C0119_02385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0119_02425	COG1280	lysine exporter protein (LysE YggA)
C0119_02440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C0119_02460	COG1113	amino acid transport
C0119_02465	COG1115	amino acid carrier protein
C0119_02500	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C0119_02505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C0119_02510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C0119_02515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0119_02540	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C0119_02550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0119_02555	COG2814	Major facilitator Superfamily
C0119_02560	COG1960	acyl-CoA dehydrogenase activity
C0119_02565	COG0583	DNA-binding transcription factor activity
C0119_02580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0119_02590	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C0119_02600	COG0037	tRNA processing
C0119_02605	COG0741	lytic transglycosylase activity
C0119_02605	COG0739	heme binding
C0119_02605	COG1196	nuclear chromosome segregation
C0119_02610	COG0501	Belongs to the peptidase M48B family
C0119_02620	COG2239	Acts as a magnesium transporter
C0119_02640	COG1253	flavin adenine dinucleotide binding
C0119_02645	COG2851	Citrate transporter
C0119_02675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C0119_02685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0119_02690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C0119_02715	COG0505	Belongs to the CarA family
C0119_02720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0119_02730	COG1309	transcriptional regulator
C0119_02735	COG0251	oxidation-reduction process
C0119_02770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0119_02795	COG0564	pseudouridine synthase activity
C0119_02805	COG0358	DNA primase activity
C0119_02810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C0119_02820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C0119_02850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0119_02855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C0119_02880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0119_02905	COG0586	Pfam SNARE associated Golgi protein
C0119_02930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0119_02935	COG2921	Belongs to the UPF0250 family
C0119_02940	COG0321	lipoyl(octanoyl) transferase activity
C0119_02955	COG0531	amino acid
C0119_02965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0119_02970	COG1648	precorrin-2 dehydrogenase activity
C0119_02970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0119_02975	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0119_02985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C0119_02995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C0119_03010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0119_03020	COG1538	Outer membrane efflux protein
C0119_03025	COG0393	Putative heavy-metal-binding
C0119_03030	COG0393	Putative heavy-metal-binding
C0119_03035	COG0242	peptide deformylase activity
C0119_03065	COG5001	Diguanylate cyclase
C0119_03065	COG4251	negative regulation of phosphorylation
C0119_03065	COG3706	GGDEF domain
C0119_03065	COG2203	Gaf domain
C0119_03075	COG1285	pathogenesis
C0119_03080	COG4681	YaeQ
C0119_03105	COG0583	DNA-binding transcription factor activity
C0119_03110	COG2814	Major facilitator Superfamily
C0119_03115	COG1309	transcriptional regulator
C0119_03120	COG1607	acyl-coa hydrolase
C0119_03130	COG1752	Esterase of the alpha-beta hydrolase superfamily
C0119_03140	COG1115	amino acid carrier protein
C0119_03145	COG0786	glutamate:sodium symporter activity
C0119_03155	COG2814	Major facilitator Superfamily
C0119_03160	COG1289	transmembrane transporter activity
C0119_03170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0119_03260	COG0840	transmembrane signaling receptor activity
C0119_03285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0119_03330	COG2826	transposase and inactivated derivatives, IS30 family
C0119_03350	COG0489	protein tyrosine kinase activity
C0119_03365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0119_03365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0119_03395	COG0004	ammonium transporteR
C0119_03410	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C0119_03420	COG2081	HI0933 family
C0119_03425	COG0668	transmembrane transport
C0119_03435	COG4302	ethanolamine ammonia-lyase activity
C0119_03445	COG0531	amino acid
C0119_03460	COG0583	DNA-binding transcription factor activity
C0119_03485	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0119_03490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0119_03495	COG0713	ATP synthesis coupled electron transport
C0119_03505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0119_03520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C0119_03540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0119_03550	COG2205	protein histidine kinase activity
C0119_03555	COG0745	RESPONSE REGULATOR receiver
C0119_03560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0119_03560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0119_03570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0119_03580	COG0640	Transcriptional regulator
C0119_03585	COG0798	PFAM Bile acid sodium symporter
C0119_03590	COG0431	NADPH-dependent FMN reductase
C0119_03635	COG0351	phosphomethylpyrimidine kinase
C0119_03635	COG0352	thiamine-phosphate diphosphorylase activity
C0119_03635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C0119_03650	COG2824	Alkylphosphonate utilization operon protein PhnA
C0119_03665	COG0564	pseudouridine synthase activity
C0119_03710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0119_03720	COG0354	folic acid binding
C0119_03755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0119_03770	COG2233	PERMEase
C0119_03780	COG0833	amino acid
C0119_03790	COG2885	chlorophyll binding
C0119_03790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C0119_03800	COG0183	Belongs to the thiolase family
C0119_03815	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0119_03825	COG2207	Transcriptional regulator
C0119_03830	COG0183	Belongs to the thiolase family
C0119_03835	COG1024	Enoyl-CoA hydratase
C0119_03835	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0119_03855	COG1272	protein, Hemolysin III
C0119_03860	COG0477	Major facilitator Superfamily
C0119_03870	COG1408	metallophosphoesterase
C0119_03875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0119_03900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C0119_03905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C0119_03980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C0119_03985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C0119_04000	COG0450	alkyl hydroperoxide reductase
C0119_04015	COG0285	dihydrofolate synthase activity
C0119_04025	COG0159	tryptophan synthase activity
C0119_04055	COG0133	tryptophan synthase activity
C0119_04065	COG4206	TonB-dependent receptor
C0119_04070	COG2096	Adenosyltransferase
C0119_04085	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C0119_04110	COG1113	amino acid transport
C0119_04130	COG0745	RESPONSE REGULATOR receiver
C0119_04135	COG2205	protein histidine kinase activity
C0119_04145	COG1960	acyl-CoA dehydrogenase activity
C0119_04150	COG1960	acyl-CoA dehydrogenase activity
C0119_04160	COG3223	Belongs to the PsiE family
C0119_04180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C0119_04190	COG1704	LemA family
C0119_04205	COG1862	Preprotein translocase
C0119_04215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0119_04225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0119_04245	COG5002	protein histidine kinase activity
C0119_04245	COG2205	protein histidine kinase activity
C0119_04245	COG0784	Response regulator, receiver
C0119_04250	COG1024	Enoyl-CoA hydratase
C0119_04255	COG2084	Dehydrogenase
C0119_04260	COG3622	Belongs to the hyi family
C0119_04275	COG0004	ammonium transporteR
C0119_04280	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C0119_04285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0119_04290	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0119_04300	COG2814	Major facilitator Superfamily
C0119_04345	COG0741	lytic transglycosylase activity
C0119_04345	COG0739	heme binding
C0119_04345	COG1196	nuclear chromosome segregation
C0119_04525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0119_04530	COG2003	Belongs to the UPF0758 family
C0119_04535	COG3781	membrane
C0119_04555	COG2350	Protein conserved in bacteria
C0119_04585	COG1607	acyl-coa hydrolase
C0119_04600	COG3453	Protein conserved in bacteria
C0119_04600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0119_04615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0119_04655	COG1183	phosphatidylcholine synthase activity
C0119_04660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C0119_04700	COG1196	nuclear chromosome segregation
C0119_04700	COG0741	lytic transglycosylase activity
C0119_04700	COG0739	heme binding
C0119_04705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0119_04710	COG1702	phosphate starvation-inducible protein PhoH
C0119_04755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0119_04780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0119_04785	COG0625	glutathione transferase activity
C0119_04820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0119_04830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C0119_04850	COG2009	succinate dehydrogenase
C0119_04870	COG3706	GGDEF domain
C0119_04875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0119_04880	COG0183	Belongs to the thiolase family
C0119_04895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0119_04900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0119_04935	COG1295	ribonuclease BN
C0119_04945	COG2169	Transcriptional regulator
C0119_04955	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0119_04990	COG0557	exoribonuclease II activity
C0119_05000	COG0339	signal peptide processing
C0119_05005	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C0119_05040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C0119_05045	COG1960	acyl-CoA dehydrogenase activity
C0119_05050	COG2072	flavoprotein involved in K transport
C0119_05055	COG0203	ribosomal protein L17
C0119_05060	COG0202	RNA polymerase activity
C0119_05065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C0119_05070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C0119_05075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0119_05080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0119_05100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C0119_05110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C0119_05115	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C0119_05165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C0119_05175	COG0089	rRNA binding
C0119_05180	COG0088	Forms part of the polypeptide exit tunnel
C0119_05200	COG0626	cystathionine gamma-synthase activity
C0119_05205	COG0433	COG0433 Predicted ATPase
C0119_05210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0119_05210	COG1017	nitric oxide dioxygenase activity
C0119_05215	COG1959	2 iron, 2 sulfur cluster binding
C0119_05235	COG1301	dicarboxylic acid transport
C0119_05240	COG1946	Acyl-CoA thioesterase
C0119_05245	COG2937	Belongs to the GPAT DAPAT family
C0119_05255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0119_05260	COG1040	competence protein
C0119_05265	COG0494	nUDIX hydrolase
C0119_05275	COG0598	Magnesium transport protein CorA
C0119_05285	COG2854	intermembrane phospholipid transfer
C0119_05290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0119_05295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0119_05300	COG1127	ABC transporter
C0119_05325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0119_05330	COG0408	coproporphyrinogen oxidase activity
C0119_05345	COG1960	acyl-CoA dehydrogenase activity
C0119_05350	COG1278	Cold shock
C0119_05360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0119_05370	COG0534	Mate efflux family protein
C0119_05385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0119_05390	COG0254	rRNA binding
C0119_05395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C0119_05410	COG2226	methyltransferase
C0119_05425	COG1192	Involved in chromosome partitioning
C0119_05430	COG0628	permease
C0119_05440	COG2814	Major facilitator Superfamily
C0119_05455	COG0277	FAD linked oxidase domain protein
C0119_05460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0119_05465	COG5006	permease, DMT superfamily
C0119_05470	COG5006	permease, DMT superfamily
C0119_05490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C0119_05495	COG5380	lipid catabolic process
C0119_05510	COG0335	large ribosomal subunit rRNA binding
C0119_05520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C0119_05525	COG0228	four-way junction DNA binding
C0119_05570	COG0194	GDP metabolic process
C0119_05575	COG1758	RNA polymerase activity
C0119_05580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0119_05600	COG0675	Transposase, IS605 OrfB family
C0119_05610	COG2906	2 iron, 2 sulfur cluster binding
C0119_05615	COG0675	Transposase, IS605 OrfB family
C0119_05625	COG3307	-O-antigen
C0119_05635	COG4969	Belongs to the N-Me-Phe pilin family
C0119_05650	COG1704	LemA family
C0119_05655	COG0493	'glutamate synthase
C0119_05660	COG0067	glutamate synthase
C0119_05660	COG0070	glutamate synthase
C0119_05660	COG0069	glutamate synthase activity
C0119_05710	COG2226	methyltransferase
C0119_05715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0119_05720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0119_05725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C0119_05745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0119_05790	COG0488	(ABC) transporter
C0119_05800	COG4221	oxidoreductase activity
C0119_05805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0119_05820	COG2111	Na H antiporter
C0119_05820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0119_05825	COG1006	Multisubunit Na H antiporter MnhC subunit
C0119_05830	COG0651	ATP synthesis coupled electron transport
C0119_05835	COG1863	multisubunit Na H antiporter MnhE subunit
C0119_05840	COG2212	antiporter activity
C0119_05850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C0119_05860	COG0195	Participates in both transcription termination and antitermination
C0119_05865	COG0779	Required for maturation of 30S ribosomal subunits
C0119_05895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0119_05920	COG0237	dephospho-CoA kinase activity
C0119_05930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0119_05935	COG3123	guanosine phosphorylase activity
C0119_05940	COG0497	DNA recombination
C0119_05950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C0119_05960	COG1132	(ABC) transporter
C0119_05970	COG1215	transferase activity, transferring glycosyl groups
C0119_05985	COG1538	Outer membrane efflux protein
C0119_05995	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C0119_06000	COG0494	nUDIX hydrolase
C0119_06005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0119_06010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0119_06015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0119_06025	COG0772	Belongs to the SEDS family
C0119_06050	COG4974	Belongs to the 'phage' integrase family
C0119_06055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0119_06065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0119_06075	COG2197	response regulator
C0119_06080	COG5002	protein histidine kinase activity
C0119_06090	COG0793	Belongs to the peptidase S41A family
C0119_06095	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C0119_06100	COG0795	lipopolysaccharide-transporting ATPase activity
C0119_06105	COG0795	lipopolysaccharide-transporting ATPase activity
C0119_06125	COG0586	Pfam SNARE associated Golgi protein
C0119_06140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0119_06140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0119_06150	COG0004	ammonium transporteR
C0119_06155	COG0347	Belongs to the P(II) protein family
C0119_06190	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C0119_06205	COG0318	PFAM AMP-dependent synthetase and ligase
C0119_06215	COG0477	Major facilitator Superfamily
C0119_06220	COG2860	membrane
C0119_06230	COG1253	flavin adenine dinucleotide binding
C0119_06260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0119_06265	COG0477	Major facilitator Superfamily
C0119_06285	COG2814	Major facilitator Superfamily
C0119_06340	COG0758	DNA mediated transformation
C0119_06350	COG0697	spore germination
C0119_06355	COG0386	Belongs to the glutathione peroxidase family
C0119_06375	COG1012	belongs to the aldehyde dehydrogenase family
C0119_06405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C0119_06415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C0119_06455	COG1121	(ABC) transporter
C0119_06460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0119_06470	COG3123	guanosine phosphorylase activity
C0119_06480	COG2837	iron assimilation
C0119_06490	COG2826	transposase and inactivated derivatives, IS30 family
C0119_06500	COG3501	Rhs element vgr protein
C0119_06505	COG0436	Aminotransferase
C0119_06510	COG0534	Mate efflux family protein
C0119_06560	COG3706	GGDEF domain
C0119_06570	COG1715	Restriction endonuclease
C0119_06575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0119_06575	COG0519	Catalyzes the synthesis of GMP from XMP
C0119_06580	COG0586	Pfam SNARE associated Golgi protein
C0119_06595	COG1192	Involved in chromosome partitioning
C0119_06640	COG3756	Protein conserved in bacteria
C0119_06770	COG3002	Belongs to the UPF0753 family
C0119_06775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0119_06785	COG3421	Type III restriction
C0119_06805	COG1484	DNA-dependent DNA replication
C0119_06830	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C0119_06835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0119_06845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0119_06855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C0119_06895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0119_06905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0119_06920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0119_06925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0119_06935	COG0297	glycogen (starch) synthase activity
C0119_06995	COG1088	dTDP-glucose 4,6-dehydratase activity
C0119_07005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C0119_07015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0119_07020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C0119_07025	COG0438	transferase activity, transferring glycosyl groups
C0119_07030	COG0438	transferase activity, transferring glycosyl groups
C0119_07035	COG0438	transferase activity, transferring glycosyl groups
C0119_07060	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C0119_07065	COG1596	polysaccharide export
C0119_07085	COG0545	Peptidyl-prolyl cis-trans isomerase
C0119_07100	COG1194	a g-specific adenine glycosylase
C0119_07115	COG2818	Glycosylase
C0119_07120	COG1064	alcohol dehydrogenase
C0119_07125	COG1943	Transposase
C0119_07130	COG0675	Transposase, IS605 OrfB family
C0119_07145	COG0783	Belongs to the Dps family
C0119_07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0119_07180	COG2233	PERMEase
C0119_07185	COG0583	DNA-binding transcription factor activity
C0119_07205	COG0129	dihydroxy-acid dehydratase activity
C0119_07230	COG0428	transporter
C0119_07240	COG0733	neurotransmitter:sodium symporter activity
C0119_07245	COG1012	belongs to the aldehyde dehydrogenase family
C0119_07255	COG0693	protein deglycase activity
C0119_07275	COG2814	Major facilitator Superfamily
C0119_07305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0119_07375	COG1063	alcohol dehydrogenase
C0119_07390	COG0187	DNA topoisomerase II activity
C0119_07400	COG0592	DNA-directed DNA polymerase activity
C0119_07410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C0119_07415	COG0594	ribonuclease P activity
C0119_07420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C0119_07425	COG0706	membrane insertase activity
C0119_07450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0119_07465	COG0402	S-adenosylhomocysteine deaminase activity
C0119_07470	COG0861	Integral membrane protein TerC family
C0119_07475	COG2814	Major facilitator Superfamily
C0119_07480	COG2388	GCN5-related N-acetyl-transferase
C0119_07505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0119_07520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C0119_07525	COG2951	lytic endotransglycosylase activity
C0119_07530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C0119_07535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C0119_07570	COG2133	pyrroloquinoline quinone binding
C0119_07585	COG1047	Peptidyl-prolyl cis-trans
C0119_07595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C0119_07600	COG0196	riboflavin kinase activity
C0119_07610	COG1309	transcriptional regulator
C0119_07615	COG1116	anion transmembrane transporter activity
C0119_07620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0119_07625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0119_07630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0119_07640	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0119_07640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0119_07660	COG1028	Short-chain dehydrogenase reductase Sdr
C0119_07665	COG0546	phosphoglycolate phosphatase activity
C0119_07670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0119_07690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0119_07695	COG1309	transcriptional regulator
C0119_07700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C0119_07710	COG3023	N-Acetylmuramoyl-L-alanine amidase
C0119_07720	COG5487	UPF0391 membrane protein
C0119_07725	COG2983	Belongs to the UPF0260 family
C0119_07730	COG3300	MHYT domain
C0119_07730	COG5001	Diguanylate cyclase
C0119_07735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0119_07740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C0119_07750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0119_07760	COG1335	isochorismatase
C0119_07765	COG0385	Bile acid
C0119_07775	COG3830	Belongs to the UPF0237 family
C0119_07775	COG0560	Phosphoserine phosphatase
C0119_07840	COG2733	membrane
C0119_07855	COG2918	glutathione biosynthetic process
C0119_07860	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C0119_07870	COG3150	esterase
C0119_07895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0119_07900	COG0410	ABC transporter
C0119_07925	COG0784	Response regulator, receiver
C0119_07925	COG2205	protein histidine kinase activity
C0119_07950	COG4266	Belongs to the allantoicase family
C0119_07955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0119_07970	COG2233	PERMEase
C0119_08025	COG1393	Belongs to the ArsC family
C0119_08030	COG0708	Exodeoxyribonuclease III
C0119_08040	COG1278	Cold shock
C0119_08055	COG2132	Multicopper oxidase
C0119_08070	COG0189	ligase activity
C0119_08095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0119_08140	COG2119	membrane
C0119_08145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0119_08145	COG0426	domain, Protein
C0119_08160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0119_08170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0119_08190	COG0640	Transcriptional regulator
C0119_08195	COG1902	pentaerythritol trinitrate reductase activity
C0119_08200	COG1519	Transferase
C0119_08205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0119_08210	COG0668	transmembrane transport
C0119_08220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0119_08235	COG0307	riboflavin synthase, alpha
C0119_08245	COG0431	NADPH-dependent FMN reductase
C0119_08260	COG0784	Response regulator, receiver
C0119_08260	COG2205	protein histidine kinase activity
C0119_08265	COG3162	membrane
C0119_08275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0119_08290	COG3706	GGDEF domain
C0119_08295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0119_08300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C0119_08300	COG0352	thiamine-phosphate diphosphorylase activity
C0119_08300	COG0351	phosphomethylpyrimidine kinase
C0119_08310	COG2814	Major facilitator Superfamily
C0119_08330	COG0450	alkyl hydroperoxide reductase
C0119_08340	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
C0119_08370	COG3158	transport of potassium into the cell
C0119_08405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C0119_08460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C0119_08465	COG0131	Imidazoleglycerol-phosphate dehydratase
C0119_08525	COG1024	Enoyl-CoA hydratase
C0119_08525	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0119_08530	COG3706	GGDEF domain
C0119_08555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0119_08575	COG3275	phosphorelay sensor kinase activity
C0119_08585	COG0181	hydroxymethylbilane synthase activity
C0119_08605	COG0824	Thioesterase
C0119_08635	COG0546	phosphoglycolate phosphatase activity
C0119_08665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0119_08685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C0119_08690	COG0081	regulation of translation
C0119_08695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C0119_08705	COG0085	RNA polymerase activity
C0119_08710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C0119_08740	COG2056	Na+-H+ antiporter family
C0119_08755	COG0326	Molecular chaperone. Has ATPase activity
C0119_08785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0119_08795	COG0427	acetyl-CoA hydrolase
C0119_08800	COG2205	protein histidine kinase activity
C0119_08805	COG0745	RESPONSE REGULATOR receiver
C0119_08825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0119_08865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C0119_08870	COG1074	ATP-dependent DNA helicase activity
C0119_08875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C0119_08885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C0119_08890	COG1185	polyribonucleotide nucleotidyltransferase activity
C0119_08895	COG2841	Protein conserved in bacteria
C0119_08900	COG0789	Transcriptional regulator
C0119_08915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C0119_08925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0119_08945	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C0119_08950	COG4535	Mg2 and Co2 transporter CorC
C0119_08975	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C0119_08975	COG0644	oxidoreductase
C0119_08985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C0119_09000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0119_09015	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C0119_09055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0119_09075	COG0751	glycine-tRNA ligase activity
C0119_09095	COG0471	metal ion transport
C0119_09105	COG1983	PspC domain protein
C0119_09130	COG0318	PFAM AMP-dependent synthetase and ligase
C0119_09135	COG1530	ribonuclease E activity
C0119_09150	COG0546	phosphoglycolate phosphatase activity
C0119_09155	COG3971	2-oxopent-4-enoate hydratase activity
C0119_09160	COG4569	acetaldehyde dehydrogenase (acetylating) activity
C0119_09195	COG0583	DNA-binding transcription factor activity
C0119_09200	COG4638	Rieske (2fe-2S)
C0119_09215	COG1028	Short-chain dehydrogenase reductase Sdr
C0119_09220	COG3384	dioxygenase
C0119_09225	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0119_09245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C0119_09250	COG1960	acyl-CoA dehydrogenase activity
C0119_09295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C0119_09310	COG0473	3-isopropylmalate dehydrogenase activity
C0119_09340	COG0252	asparaginase activity
C0119_09370	COG1560	Kdo2-lipid A biosynthetic process
C0119_09410	COG1929	Belongs to the glycerate kinase type-1 family
C0119_09415	COG0210	DNA helicase
C0119_09420	COG0724	RNA recognition motif
C0119_09440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0119_09440	COG4651	solute:proton antiporter activity
C0119_09445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0119_09450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0119_09465	COG0788	formyltetrahydrofolate deformylase activity
C0119_09500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C0119_09505	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C0119_09555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0119_09555	COG2813	Specifically methylates the guanine in position
C0119_09560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0119_09565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0119_09570	COG4774	siderophore transport
C0119_09580	COG3128	pkhd-type hydroxylase
C0119_09585	COG4774	siderophore transport
C0119_09590	COG4774	siderophore transport
C0119_09600	COG0740	serine-type endopeptidase activity
C0119_09615	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C0119_09615	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C0119_09625	COG0280	phosphate acetyltransferase
C0119_09625	COG0857	belongs to the CobB CobQ family
C0119_09630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C0119_09655	COG0793	Belongs to the peptidase S41A family
C0119_09670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C0119_09685	COG0084	hydrolase, TatD family'
C0119_09715	COG1162	GTPase activity
C0119_09720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C0119_09730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0119_09740	COG1538	Outer membrane efflux protein
C0119_09745	COG0577	efflux transmembrane transporter activity
C0119_09745	COG1136	(ABC) transporter
C0119_09750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0119_09775	COG0028	Belongs to the TPP enzyme family
C0119_09780	COG0440	acetolactate synthase activity
C0119_09790	COG2826	transposase and inactivated derivatives, IS30 family
C0119_09820	COG2975	iron-sulfur cluster assembly
C0119_09840	COG1426	Protein conserved in bacteria
C0119_09850	COG0124	histidyl-tRNA synthetase
C0119_09860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0119_09875	COG1028	Short-chain dehydrogenase reductase Sdr
C0119_09880	COG3956	TIGRFAM MazG family protein
C0119_09885	COG1555	photosystem II stabilization
C0119_09890	COG0617	tRNA 3'-terminal CCA addition
C0119_09895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0119_09910	COG1660	Displays ATPase and GTPase activities
C0119_09930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C0119_10020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C0119_10040	COG0318	PFAM AMP-dependent synthetase and ligase
C0119_10065	COG0546	phosphoglycolate phosphatase activity
C0119_10070	COG1943	Transposase
C0119_10075	COG0675	Transposase, IS605 OrfB family
C0119_10090	COG0625	glutathione transferase activity
C0119_10100	COG1238	metal cluster binding
C0119_10115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0119_10130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0119_10170	COG0037	tRNA processing
C0119_10220	COG1764	response to oxidative stress
C0119_10225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0119_10280	COG2969	positive regulation of protein catabolic process
C0119_10285	COG0625	glutathione transferase activity
C0119_10290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C0119_10295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C0119_10300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C0119_10305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C0119_10310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0119_10335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0119_10350	COG0494	nUDIX hydrolase
C0119_10360	COG1214	PFAM Peptidase M22, glycoprotease
C0119_10365	COG1968	undecaprenyl-diphosphatase activity
C0119_10385	COG4269	membrane
C0119_10400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C0119_10410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0119_10435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0119_10440	COG3545	Serine hydrolase
C0119_10445	COG3545	Serine hydrolase
C0119_10455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C0119_10455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C0119_10460	COG0730	response to heat
C0119_10470	COG1196	nuclear chromosome segregation
C0119_10480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0119_10485	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C0119_10490	COG2193	ferroxidase activity
C0119_10505	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0119_10510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C0119_10530	COG0009	L-threonylcarbamoyladenylate synthase
C0119_10535	COG3101	peptidyl-lysine hydroxylation
C0119_10540	COG1399	metal-binding, possibly nucleic acid-binding protein
C0119_10545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C0119_10555	COG1028	Short-chain dehydrogenase reductase Sdr
C0119_10560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0119_10565	COG1652	LysM domain
C0119_10570	COG1522	sequence-specific DNA binding
C0119_10585	COG0251	oxidation-reduction process
C0119_10590	COG1113	amino acid transport
C0119_10610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C0119_10625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0119_10635	COG0456	acetyltransferase
C0119_10640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C0119_10645	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C0119_10650	COG0492	ferredoxin-NADP+ reductase activity
C0119_10675	COG0850	regulation of cytokinetic process
C0119_10685	COG0204	Acyl-transferase
C0119_10690	COG2885	chlorophyll binding
C0119_10695	COG0210	DNA helicase
C0119_10700	COG0756	dUTP diphosphatase activity
C0119_10705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0119_10715	COG0121	glutamine amidotransferase
C0119_10730	COG2914	Belongs to the UPF0125 (RnfH) family
C0119_10735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0119_10740	COG0735	belongs to the Fur family
C0119_10770	COG0420	3'-5' exonuclease activity
C0119_10795	COG2050	protein possibly involved in aromatic compounds catabolism
C0119_10810	COG0582	viral genome integration into host DNA
C0119_10855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0119_10870	COG2826	transposase and inactivated derivatives, IS30 family
C0119_10915	COG3300	MHYT domain
C0119_10915	COG5001	Diguanylate cyclase
C0119_10940	COG3177	Filamentation induced by cAMP protein fic
C0119_10945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0119_10960	COG0625	glutathione transferase activity
C0119_10975	COG1448	Aminotransferase
C0119_10980	COG1113	amino acid transport
C0119_11000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C0119_11005	COG0596	Alpha beta hydrolase
C0119_11020	COG4106	trans-aconitate 2-methyltransferase activity
C0119_11045	COG1294	oxidase, subunit
C0119_11060	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C0119_11090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C0119_11100	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C0119_11105	COG1077	Cell shape determining protein MreB Mrl
C0119_11110	COG1792	Involved in formation and maintenance of cell shape
C0119_11115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C0119_11125	COG1530	ribonuclease E activity
C0119_11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0119_11160	COG1113	amino acid transport
C0119_11165	COG2828	Protein conserved in bacteria
C0119_11170	COG0142	geranyltranstransferase activity
C0119_11175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0119_11210	COG0546	phosphoglycolate phosphatase activity
C0119_11215	COG2323	membrane
C0119_11230	COG2852	Protein conserved in bacteria
C0119_11240	COG0525	valine-tRNA ligase activity
C0119_11250	COG0300	oxidoreductase activity
C0119_11255	COG2066	Belongs to the glutaminase family
C0119_11260	COG2376	Dihydroxyacetone kinase
C0119_11290	COG0306	phosphate transporter
C0119_11335	COG4181	ATPase activity
C0119_11340	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C0119_11350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0119_11360	COG0583	DNA-binding transcription factor activity
C0119_11370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0119_11375	COG1773	rubredoxin
C0119_11380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0119_11400	COG2354	Protein conserved in bacteria
C0119_11405	COG2321	neutral zinc metallopeptidase
C0119_11440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0119_11440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C0119_11445	COG2826	transposase and inactivated derivatives, IS30 family
C0119_11460	COG2009	succinate dehydrogenase
C0119_11465	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C0119_11470	COG1053	succinate dehydrogenase
C0119_11475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0119_11490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0119_11500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0119_11510	COG1649	PFAM Uncharacterised BCR, COG1649
C0119_11510	COG0726	polysaccharide deacetylase
C0119_11515	COG1215	transferase activity, transferring glycosyl groups
C0119_11525	COG1649	PFAM Uncharacterised BCR, COG1649
C0119_11525	COG0726	polysaccharide deacetylase
C0119_11530	COG2268	Band 7 protein
C0119_11545	COG0175	sulfate reduction
C0119_11595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0119_11670	COG0742	ribosomal rna small subunit methyltransferase
C0119_11675	COG0768	penicillin binding
C0119_11700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0119_11705	COG2878	Part of a membrane complex involved in electron transport
C0119_11710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0119_11720	COG3384	dioxygenase
C0119_11730	COG2234	aminopeptidase activity
C0119_11740	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0119_11775	COG0006	proline dipeptidase activity
C0119_11780	COG2826	transposase and inactivated derivatives, IS30 family
C0119_11790	COG2155	Conserved Protein
C0119_11805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0119_11810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0119_11860	COG1388	LysM domain
C0119_11860	COG0741	lytic transglycosylase activity
C0119_11865	COG4166	transmembrane transport
C0119_11870	COG4174	ABC transporter (Permease)
C0119_11875	COG4239	(ABC) transporter, permease
C0119_11880	COG4172	Belongs to the ABC transporter superfamily
C0119_11920	COG0833	amino acid
C0119_11930	COG4771	TonB-dependent receptor
C0119_11940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0119_11945	COG0418	dihydroorotase activity
C0119_11950	COG4251	negative regulation of phosphorylation
C0119_11950	COG5001	Diguanylate cyclase
C0119_11950	COG2203	Gaf domain
C0119_11950	COG3706	GGDEF domain
C0119_11960	COG1620	l-lactate permease
C0119_11965	COG2186	Transcriptional regulator
C0119_11975	COG0277	FAD linked oxidase domain protein
C0119_11985	COG1902	pentaerythritol trinitrate reductase activity
C0119_11985	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0119_11995	COG0642	Histidine kinase
C0119_12000	COG0745	RESPONSE REGULATOR receiver
C0119_12010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0119_12025	COG0640	Transcriptional regulator
C0119_12060	COG1741	Belongs to the pirin family
C0119_12075	COG3739	integral membrane protein
C0119_12090	COG3706	GGDEF domain
C0119_12105	COG0302	gtp cyclohydrolase
C0119_12120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C0119_12125	COG0512	Glutamine amidotransferase of anthranilate synthase
C0119_12145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0119_12185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0119_12195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0119_12215	COG1335	isochorismatase
C0119_12220	COG0251	oxidation-reduction process
C0119_12225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0119_12230	COG2233	PERMEase
C0119_12235	COG2084	Dehydrogenase
C0119_12245	COG1960	acyl-CoA dehydrogenase activity
C0119_12250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C0119_12255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0119_12295	COG0556	nucleotide-excision repair
C0119_12325	COG1733	regulation of RNA biosynthetic process
C0119_12330	COG2814	Major facilitator Superfamily
C0119_12340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0119_12345	COG0671	phosphoesterase, PA-phosphatase related
C0119_12355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0119_12360	COG0076	glutamate decarboxylase activity
C0119_12370	COG0573	inorganic phosphate transmembrane transporter activity
C0119_12380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0119_12390	COG0616	signal peptide processing
C0119_12450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C0119_12455	COG1686	Belongs to the peptidase S11 family
C0119_12480	COG0583	DNA-binding transcription factor activity
C0119_12485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0119_12490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0119_12495	COG1067	ATP-dependent peptidase activity
C0119_12535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C0119_12540	COG1966	Carbon starvation protein
C0119_12545	COG2879	small protein
C0119_12550	COG0714	Associated with various cellular activities
C0119_12575	COG0281	malic enzyme
C0119_12595	COG1136	(ABC) transporter
C0119_12620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0119_12625	COG1765	OsmC-like protein
C0119_12635	COG0667	Aldo Keto reductase
C0119_12655	COG0540	Belongs to the ATCase OTCase family
C0119_12665	COG3047	cAMP biosynthetic process
C0119_12665	COG2885	chlorophyll binding
C0119_12685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C0119_12690	COG0659	secondary active sulfate transmembrane transporter activity
C0119_12710	COG2363	Small membrane protein
C0119_12725	COG1278	Cold shock
C0119_12730	COG0513	Belongs to the DEAD box helicase family
C0119_12740	COG0778	Nitroreductase
C0119_12795	COG4783	chaperone-mediated protein folding
C0119_12810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0119_12820	COG2203	Gaf domain
C0119_12820	COG2199	diguanylate cyclase activity
C0119_12875	COG2815	serine threonine protein kinase
C0119_12875	COG0515	serine threonine protein kinase
C0119_12925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0119_12930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0119_12940	COG0612	Peptidase, M16
C0119_12945	COG3618	amidohydrolase
C0119_12965	COG3025	triphosphatase activity
C0119_12980	COG0352	thiamine-phosphate diphosphorylase activity
C0119_13025	COG1309	transcriptional regulator
C0119_13090	COG2391	methyltransferase activity
C0119_13100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0119_13105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0119_13115	COG0456	acetyltransferase
C0119_13120	COG2353	YceI-like domain
C0119_13125	COG0519	Catalyzes the synthesis of GMP from XMP
C0119_13125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0119_13140	COG1028	Short-chain dehydrogenase reductase Sdr
C0119_13145	COG2826	transposase and inactivated derivatives, IS30 family
C0119_13170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C0119_13170	COG0517	IMP dehydrogenase activity
C0119_13175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C0119_13185	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C0119_13190	COG1137	ATPase activity
C0119_13220	COG0589	response to stress
C0119_13235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C0119_13245	COG2203	Gaf domain
C0119_13245	COG5001	Diguanylate cyclase
C0119_13245	COG4251	negative regulation of phosphorylation
C0119_13245	COG3706	GGDEF domain
C0119_13280	COG2011	ABC-type metal ion transport system permease component
C0119_13285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C0119_13290	COG1464	Belongs to the NlpA lipoprotein family
C0119_13305	COG0151	Belongs to the GarS family
C0119_13310	COG0138	bifunctional purine biosynthesis protein purh
C0119_13315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C0119_13345	COG0445	tRNA wobble uridine modification
C0119_13370	COG3852	Histidine kinase
C0119_13390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C0119_13395	COG0575	Belongs to the CDS family
C0119_13410	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0119_13425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0119_13430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0119_13445	COG2137	regulation of response to DNA damage stimulus
C0119_13455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C0119_13460	COG1011	Hydrolase
C0119_13465	COG1218	3'(2'),5'-bisphosphate nucleotidase
C0119_13475	COG0268	Binds directly to 16S ribosomal RNA
C0119_13480	COG0702	epimerase
C0119_13485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C0119_13490	COG0625	glutathione transferase activity
C0119_13495	COG2850	peptidyl-arginine hydroxylation
C0119_13505	COG0424	maF-like protein
C0119_13530	COG0697	spore germination
C0119_13560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0119_13565	COG3781	membrane
C0119_13585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C0119_13585	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C0119_13585	COG0506	proline dehydrogenase activity
C0119_13595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0119_13600	COG1027	Aspartate ammonia-lyase
C0119_13640	COG0316	Belongs to the HesB IscA family
C0119_13645	COG0822	iron-sulfur transferase activity
C0119_13670	COG0776	regulation of translation
C0119_13675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0119_13695	COG1585	Membrane protein implicated in regulation of membrane protease activity
C0119_13705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0119_13725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0119_13730	COG0569	domain protein
C0119_13735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0119_13750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0119_13775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C0119_13780	COG0542	response to heat
C0119_13795	COG0477	Major facilitator Superfamily
C0119_13815	COG0372	Belongs to the citrate synthase family
C0119_13830	COG1546	Belongs to the CinA family
C0119_13830	COG1058	Belongs to the CinA family
C0119_13840	COG2826	transposase and inactivated derivatives, IS30 family
C0119_13880	COG2814	Major facilitator Superfamily
C0119_13890	COG3706	GGDEF domain
C0119_13900	COG0439	Biotin carboxylase
C0119_13915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0119_13940	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C0119_13945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0119_13975	COG0596	Alpha beta hydrolase
C0119_14065	COG3550	peptidyl-serine autophosphorylation
C0119_14075	COG2072	flavoprotein involved in K transport
C0119_14085	COG2144	transferase activity, transferring acyl groups
C0119_14110	COG3604	Transcriptional regulator
C0119_14120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0119_14135	COG4221	oxidoreductase activity
C0119_14150	COG0642	Histidine kinase
C0119_14155	COG0745	RESPONSE REGULATOR receiver
C0119_14160	COG2194	sulfuric ester hydrolase activity
C0119_14175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0119_14200	COG0515	serine threonine protein kinase
C0119_14205	COG2116	formate transmembrane transporter activity
C0119_14210	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
C0119_14220	COG0402	S-adenosylhomocysteine deaminase activity
C0119_14265	COG0583	DNA-binding transcription factor activity
C0119_14280	COG1877	trehalose-phosphatase activity
C0119_14285	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C0119_14315	COG1944	ATP diphosphatase activity
C0119_14335	COG1309	transcriptional regulator
C0119_14340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0119_14370	COG2223	nitrite transmembrane transporter activity
C0119_14375	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C0119_14380	COG4149	molybdate abc transporter
C0119_14385	COG0725	ABC transporter, periplasmic molybdate-binding protein
C0119_14390	COG0303	'Molybdopterin
C0119_14395	COG0315	cyclic pyranopterin monophosphate synthase activity
C0119_14395	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0119_14400	COG0314	molybdopterin synthase activity
C0119_14410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C0119_14420	COG0243	molybdopterin cofactor binding
C0119_14425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0119_14430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0119_14435	COG2223	nitrite transmembrane transporter activity
C0119_14450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0119_14450	COG1116	anion transmembrane transporter activity
C0119_14455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0119_14460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0119_14480	COG1064	alcohol dehydrogenase
C0119_14505	COG0864	Transcriptional regulator
C0119_14515	COG0439	Biotin carboxylase
C0119_14530	COG0583	DNA-binding transcription factor activity
C0119_14535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0119_14580	COG1017	nitric oxide dioxygenase activity
C0119_14580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0119_14585	COG0318	PFAM AMP-dependent synthetase and ligase
C0119_14590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0119_14600	COG2814	Major facilitator Superfamily
C0119_14605	COG0583	DNA-binding transcription factor activity
C0119_14610	COG4948	Mandelate Racemase Muconate Lactonizing
C0119_14615	COG4829	muconolactone delta-isomerase
C0119_14625	COG4638	Rieske (2fe-2S)
C0119_14630	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C0119_14635	COG0633	Ferredoxin
C0119_14635	COG0543	2 iron, 2 sulfur cluster binding
C0119_14640	COG1028	Short-chain dehydrogenase reductase Sdr
C0119_14645	COG3135	benzoate transporter
C0119_14650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C0119_14655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0119_14660	COG0183	Belongs to the thiolase family
C0119_14665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0119_14685	COG2826	transposase and inactivated derivatives, IS30 family
C0119_14700	COG0831	urea catabolic process
C0119_14705	COG0829	nickel cation binding
C0119_14715	COG0830	nickel cation binding
C0119_14740	COG0789	Transcriptional regulator
C0119_14750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0119_14755	COG0640	Transcriptional regulator
C0119_14770	COG3619	membrane
C0119_14775	COG3122	Protein conserved in bacteria
C0119_14790	COG0668	transmembrane transport
C0119_14795	COG1132	(ABC) transporter
C0119_14800	COG2030	dehydratase
C0119_14810	COG0509	glycine decarboxylation via glycine cleavage system
C0119_14815	COG2814	Major facilitator Superfamily
C0119_14830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0119_14840	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C0119_14910	COG1525	nuclease
C0119_14930	COG2169	Transcriptional regulator
C0119_14935	COG1960	acyl-CoA dehydrogenase activity
C0119_14945	COG2207	Transcriptional regulator
C0119_14950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0119_14955	COG0730	response to heat
C0119_14960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0119_15015	COG1475	DNA binding
C0119_15020	COG1192	Involved in chromosome partitioning
C0119_15075	COG3316	Transposase and inactivated derivatives
C0119_15100	COG0789	Transcriptional regulator
C0119_15265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0119_15310	COG3284	Transcriptional regulator
C0119_15375	COG3316	Transposase and inactivated derivatives
C0119_15390	COG3316	Transposase and inactivated derivatives
C0119_15425	COG4372	Transposase
C0119_15460	COG1401	restriction endodeoxyribonuclease activity
C0119_15475	COG0659	secondary active sulfate transmembrane transporter activity
C0119_15480	COG0589	response to stress
C0119_15510	COG3316	Transposase and inactivated derivatives
C0119_15565	COG3316	Transposase and inactivated derivatives
C0119_15590	COG3316	Transposase and inactivated derivatives
C0119_15600	COG0604	alcohol dehydrogenase
C0119_15620	COG1063	alcohol dehydrogenase
C0119_15640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0119_15715	COG2814	Major facilitator Superfamily
C0119_15765	COG0789	Transcriptional regulator
C0119_15790	COG0582	viral genome integration into host DNA
C0119_15795	COG2369	cell adhesion
C0119_15820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair