locus-tag	class	description
IC768_00010	COG0592	DNA-directed DNA polymerase activity
IC768_00020	COG0187	DNA topoisomerase II activity
IC768_00030	COG0586	Pfam SNARE associated Golgi protein
IC768_00035	COG0488	(ABC) transporter
IC768_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC768_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC768_00105	COG0625	glutathione transferase activity
IC768_00115	COG0733	neurotransmitter:sodium symporter activity
IC768_00155	COG2233	PERMEase
IC768_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_00205	COG2814	Major facilitator Superfamily
IC768_00210	COG0656	L-ascorbic acid biosynthetic process
IC768_00215	COG0583	DNA-binding transcription factor activity
IC768_00235	COG1064	alcohol dehydrogenase
IC768_00240	COG2818	Glycosylase
IC768_00255	COG1194	a g-specific adenine glycosylase
IC768_00270	COG5487	UPF0391 membrane protein
IC768_00275	COG2983	Belongs to the UPF0260 family
IC768_00280	COG2133	pyrroloquinoline quinone binding
IC768_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC768_00290	COG2116	formate transmembrane transporter activity
IC768_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC768_00315	COG1335	isochorismatase
IC768_00320	COG0385	Bile acid
IC768_00325	COG0534	Mate efflux family protein
IC768_00330	COG1683	Conserved Protein
IC768_00345	COG0346	lactoylglutathione lyase activity
IC768_00350	COG0625	glutathione transferase activity
IC768_00360	COG1113	amino acid transport
IC768_00370	COG0523	cobalamin synthesis protein
IC768_00380	COG2188	Transcriptional regulator
IC768_00410	COG0010	Belongs to the arginase family
IC768_00420	COG0546	phosphoglycolate phosphatase activity
IC768_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC768_00430	COG1280	lysine exporter protein (LysE YggA)
IC768_00460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC768_00470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC768_00475	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC768_00570	COG0534	Mate efflux family protein
IC768_00575	COG0436	Aminotransferase
IC768_00580	COG2733	membrane
IC768_00595	COG2918	glutathione biosynthetic process
IC768_00610	COG1388	LysM domain
IC768_00610	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC768_00650	COG3150	esterase
IC768_00660	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC768_00670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC768_00680	COG2233	PERMEase
IC768_00685	COG2351	hydroxyisourate hydrolase activity
IC768_00705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC768_00705	COG0666	response to abiotic stimulus
IC768_00720	COG3706	GGDEF domain
IC768_00735	COG1393	Belongs to the ArsC family
IC768_00740	COG0708	Exodeoxyribonuclease III
IC768_00765	COG0189	ligase activity
IC768_00785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC768_00795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC768_00810	COG4942	peptidase
IC768_00820	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC768_00830	COG2119	membrane
IC768_00835	COG0426	domain, Protein
IC768_00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC768_00860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC768_00880	COG1902	pentaerythritol trinitrate reductase activity
IC768_00885	COG1519	Transferase
IC768_00890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC768_00895	COG0668	transmembrane transport
IC768_00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC768_00910	COG1335	isochorismatase
IC768_00915	COG1522	sequence-specific DNA binding
IC768_00940	COG0784	Response regulator, receiver
IC768_00940	COG2205	protein histidine kinase activity
IC768_00940	COG2198	Histidine kinase
IC768_00945	COG3162	membrane
IC768_00950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC768_00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC768_00980	COG1309	transcriptional regulator
IC768_01000	COG4221	oxidoreductase activity
IC768_01010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC768_01010	COG0352	thiamine-phosphate diphosphorylase activity
IC768_01010	COG0351	phosphomethylpyrimidine kinase
IC768_01020	COG2814	Major facilitator Superfamily
IC768_01035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC768_01045	COG1113	amino acid transport
IC768_01055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC768_01060	COG1012	belongs to the aldehyde dehydrogenase family
IC768_01070	COG1335	isochorismatase
IC768_01105	COG2814	Major facilitator Superfamily
IC768_01110	COG0583	DNA-binding transcription factor activity
IC768_01130	COG0667	Aldo Keto reductase
IC768_01150	COG1733	regulation of RNA biosynthetic process
IC768_01175	COG1733	regulation of RNA biosynthetic process
IC768_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC768_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC768_01290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC768_01320	COG0427	acetyl-CoA hydrolase
IC768_01350	COG0659	secondary active sulfate transmembrane transporter activity
IC768_01355	COG4221	oxidoreductase activity
IC768_01365	COG0028	Belongs to the TPP enzyme family
IC768_01370	COG0488	(ABC) transporter
IC768_01445	COG0833	amino acid
IC768_01490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC768_01495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC768_01510	COG2226	methyltransferase
IC768_01560	COG0070	glutamate synthase
IC768_01560	COG0067	glutamate synthase
IC768_01560	COG0069	glutamate synthase activity
IC768_01565	COG0493	'glutamate synthase
IC768_01575	COG1704	LemA family
IC768_01580	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC768_01590	COG4969	Belongs to the N-Me-Phe pilin family
IC768_01600	COG3307	-O-antigen
IC768_01620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC768_01635	COG0194	GDP metabolic process
IC768_01650	COG4969	Belongs to the N-Me-Phe pilin family
IC768_01675	COG4969	Belongs to the N-Me-Phe pilin family
IC768_01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC768_01700	COG0335	large ribosomal subunit rRNA binding
IC768_01710	COG5380	lipid catabolic process
IC768_01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC768_01735	COG5006	permease, DMT superfamily
IC768_01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC768_01745	COG0277	FAD linked oxidase domain protein
IC768_01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC768_01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC768_01775	COG1289	transmembrane transporter activity
IC768_01785	COG0628	permease
IC768_01790	COG1192	Involved in chromosome partitioning
IC768_01820	COG0833	amino acid
IC768_01825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC768_01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC768_01840	COG1012	belongs to the aldehyde dehydrogenase family
IC768_01880	COG0583	DNA-binding transcription factor activity
IC768_01885	COG1794	racemase activity, acting on amino acids and derivatives
IC768_01890	COG0583	DNA-binding transcription factor activity
IC768_01910	COG0752	glycyl-tRNA synthetase alpha subunit
IC768_01935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC768_01935	COG0617	tRNA 3'-terminal CCA addition
IC768_01935	COG0517	IMP dehydrogenase activity
IC768_01940	COG1983	PspC domain protein
IC768_01950	COG1960	acyl-CoA dehydrogenase activity
IC768_01965	COG0408	coproporphyrinogen oxidase activity
IC768_01985	COG0513	Belongs to the DEAD box helicase family
IC768_01990	COG1127	ABC transporter
IC768_01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC768_02005	COG2854	intermembrane phospholipid transfer
IC768_02015	COG0598	Magnesium transport protein CorA
IC768_02025	COG0494	nUDIX hydrolase
IC768_02030	COG1040	competence protein
IC768_02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC768_02050	COG2937	Belongs to the GPAT DAPAT family
IC768_02055	COG1946	Acyl-CoA thioesterase
IC768_02060	COG1301	dicarboxylic acid transport
IC768_02075	COG1959	2 iron, 2 sulfur cluster binding
IC768_02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC768_02080	COG1017	nitric oxide dioxygenase activity
IC768_02085	COG0433	COG0433 Predicted ATPase
IC768_02090	COG0626	cystathionine gamma-synthase activity
IC768_02105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC768_02110	COG0088	Forms part of the polypeptide exit tunnel
IC768_02245	COG1960	acyl-CoA dehydrogenase activity
IC768_02250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC768_02280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC768_02285	COG0339	signal peptide processing
IC768_02290	COG0557	exoribonuclease II activity
IC768_02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC768_02340	COG2169	Transcriptional regulator
IC768_02350	COG1295	ribonuclease BN
IC768_02385	COG1702	phosphate starvation-inducible protein PhoH
IC768_02395	COG0739	heme binding
IC768_02395	COG1196	nuclear chromosome segregation
IC768_02395	COG0741	lytic transglycosylase activity
IC768_02425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC768_02430	COG1183	phosphatidylcholine synthase activity
IC768_02495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC768_02500	COG1309	transcriptional regulator
IC768_02515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC768_02520	COG1960	acyl-CoA dehydrogenase activity
IC768_02525	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC768_02525	COG1024	Enoyl-CoA hydratase
IC768_02560	COG2969	positive regulation of protein catabolic process
IC768_02570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC768_02575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC768_02580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC768_02585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC768_02590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC768_02610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC768_02620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC768_02625	COG1408	metallophosphoesterase
IC768_02635	COG2199	diguanylate cyclase activity
IC768_02670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC768_02695	COG1607	acyl-coa hydrolase
IC768_02730	COG2350	Protein conserved in bacteria
IC768_02740	COG0613	PHP domain protein
IC768_02745	COG3781	membrane
IC768_02755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC768_02760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC768_02770	COG1862	Preprotein translocase
IC768_02805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC768_02815	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC768_02830	COG2194	sulfuric ester hydrolase activity
IC768_02840	COG0726	polysaccharide deacetylase
IC768_02845	COG0463	Glycosyl transferase, family 2
IC768_02850	COG0438	transferase activity, transferring glycosyl groups
IC768_02890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC768_02925	COG1960	acyl-CoA dehydrogenase activity
IC768_02930	COG1960	acyl-CoA dehydrogenase activity
IC768_02940	COG2205	protein histidine kinase activity
IC768_02945	COG0745	RESPONSE REGULATOR receiver
IC768_02955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC768_02975	COG2096	Adenosyltransferase
IC768_02980	COG4206	TonB-dependent receptor
IC768_03030	COG0285	dihydrofolate synthase activity
IC768_03050	COG0450	alkyl hydroperoxide reductase
IC768_03065	COG0477	Major facilitator Superfamily
IC768_03070	COG1272	protein, Hemolysin III
IC768_03080	COG2153	protein acetylation
IC768_03100	COG0183	Belongs to the thiolase family
IC768_03105	COG2207	Transcriptional regulator
IC768_03125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC768_03150	COG2885	chlorophyll binding
IC768_03150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC768_03160	COG1690	Belongs to the RtcB family
IC768_03165	COG0833	amino acid
IC768_03175	COG2233	PERMEase
IC768_03180	COG1217	gtp-binding protein TYPA
IC768_03205	COG2094	Belongs to the DNA glycosylase MPG family
IC768_03210	COG4772	TonB-dependent receptor
IC768_03215	COG1902	pentaerythritol trinitrate reductase activity
IC768_03220	COG0679	Auxin Efflux Carrier
IC768_03230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC768_03235	COG0354	folic acid binding
IC768_03250	COG2233	PERMEase
IC768_03255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC768_03260	COG0251	oxidation-reduction process
IC768_03265	COG1335	isochorismatase
IC768_03270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_03280	COG0596	Alpha beta hydrolase
IC768_03285	COG3189	MarR family transcriptional regulator
IC768_03290	COG2824	Alkylphosphonate utilization operon protein PhnA
IC768_03295	COG3422	double-strand break repair
IC768_03335	COG0840	transmembrane signaling receptor activity
IC768_03350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC768_03375	COG2832	Protein of unknown function (DUF454)
IC768_03380	COG1376	ErfK ybiS ycfS ynhG family protein
IC768_03430	COG1289	transmembrane transporter activity
IC768_03435	COG2814	Major facilitator Superfamily
IC768_03455	COG1115	amino acid carrier protein
IC768_03460	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC768_03465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC768_03470	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC768_03500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC768_03510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC768_03515	COG1077	Cell shape determining protein MreB Mrl
IC768_03520	COG1792	Involved in formation and maintenance of cell shape
IC768_03525	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC768_03530	COG0424	maF-like protein
IC768_03535	COG1530	ribonuclease E activity
IC768_03545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC768_03565	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC768_03590	COG2207	Transcriptional regulator
IC768_03620	COG3046	protein related to deoxyribodipyrimidine photolyase
IC768_03625	COG2816	NAD+ diphosphatase activity
IC768_03630	COG1113	amino acid transport
IC768_03635	COG2828	Protein conserved in bacteria
IC768_03640	COG0142	geranyltranstransferase activity
IC768_03645	COG2315	Protein conserved in bacteria
IC768_03660	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC768_03680	COG2194	sulfuric ester hydrolase activity
IC768_03685	COG0745	RESPONSE REGULATOR receiver
IC768_03690	COG0642	Histidine kinase
IC768_03700	COG0004	ammonium transporteR
IC768_03705	COG0583	DNA-binding transcription factor activity
IC768_03725	COG0525	valine-tRNA ligase activity
IC768_03735	COG0525	valine-tRNA ligase activity
IC768_03745	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_03755	COG0393	Putative heavy-metal-binding
IC768_03760	COG0393	Putative heavy-metal-binding
IC768_03765	COG1538	Outer membrane efflux protein
IC768_03775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_03780	COG0671	phosphoesterase, PA-phosphatase related
IC768_03810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC768_03825	COG1648	precorrin-2 dehydrogenase activity
IC768_03825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC768_03830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC768_03835	COG1733	regulation of RNA biosynthetic process
IC768_03845	COG0531	amino acid
IC768_03860	COG0321	lipoyl(octanoyl) transferase activity
IC768_03865	COG2921	Belongs to the UPF0250 family
IC768_03900	COG2009	succinate dehydrogenase
IC768_03905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC768_03910	COG1053	succinate dehydrogenase
IC768_03915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC768_03940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC768_03960	COG2354	Protein conserved in bacteria
IC768_03965	COG2321	neutral zinc metallopeptidase
IC768_03985	COG2843	Capsule synthesis protein
IC768_04005	COG0589	response to stress
IC768_04025	COG0505	Belongs to the CarA family
IC768_04050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC768_04055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC768_04105	COG0477	Major facilitator Superfamily
IC768_04110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC768_04125	COG1597	lipid kinase activity
IC768_04130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IC768_04150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC768_04155	COG0584	glycerophosphoryl diester phosphodiesterase
IC768_04175	COG0741	lytic transglycosylase activity
IC768_04195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC768_04200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC768_04260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC768_04260	COG0644	oxidoreductase
IC768_04265	COG1960	acyl-CoA dehydrogenase activity
IC768_04270	COG1024	Enoyl-CoA hydratase
IC768_04275	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC768_04280	COG0183	Belongs to the thiolase family
IC768_04285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC768_04305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_04310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_04325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC768_04345	COG3811	Belongs to the UPF0386 family
IC768_04410	COG1309	transcriptional regulator
IC768_04415	COG1902	pentaerythritol trinitrate reductase activity
IC768_04420	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC768_04420	COG0596	Alpha beta hydrolase
IC768_04425	COG0596	Alpha beta hydrolase
IC768_04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC768_04430	COG0596	Alpha beta hydrolase
IC768_04435	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_04440	COG0583	DNA-binding transcription factor activity
IC768_04445	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC768_04450	COG1012	belongs to the aldehyde dehydrogenase family
IC768_04470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_04475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_04480	COG0778	Nitroreductase
IC768_04495	COG1929	Belongs to the glycerate kinase type-1 family
IC768_04500	COG0243	molybdopterin cofactor binding
IC768_04505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC768_04510	COG3339	Conserved Protein
IC768_04535	COG1115	amino acid carrier protein
IC768_04540	COG1113	amino acid transport
IC768_04550	COG0019	diaminopimelate decarboxylase activity
IC768_04565	COG1280	lysine exporter protein (LysE YggA)
IC768_04570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC768_04590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC768_04600	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC768_04610	COG0463	Glycosyl transferase, family 2
IC768_04630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_04665	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC768_04670	COG1136	(ABC) transporter
IC768_04685	COG0616	signal peptide processing
IC768_04685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC768_04690	COG0596	Alpha beta hydrolase
IC768_04695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC768_04705	COG0628	permease
IC768_04740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC768_04760	COG0823	Involved in the tonB-independent uptake of proteins
IC768_04780	COG0824	Thioesterase
IC768_04785	COG1473	amidohydrolase
IC768_04810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC768_04810	COG0047	phosphoribosylformylglycinamidine synthase activity
IC768_04815	COG2814	Major facilitator Superfamily
IC768_04830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC768_04835	COG1024	Enoyl-CoA hydratase
IC768_04840	COG1051	belongs to the nudix hydrolase family
IC768_04840	COG1056	cytidyltransferase-related domain
IC768_04855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC768_04870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC768_04875	COG0602	queuosine metabolic process
IC768_04885	COG4625	pathogenesis
IC768_04890	COG0583	DNA-binding transcription factor activity
IC768_04895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC768_04900	COG4208	sulfate ABC transporter
IC768_04905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC768_04915	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC768_04920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC768_04925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC768_04945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC768_04955	COG0481	GTPase activity
IC768_04960	COG0681	Belongs to the peptidase S26 family
IC768_04975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC768_04985	COG1381	Involved in DNA repair and RecF pathway recombination
IC768_04990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC768_05000	COG4221	oxidoreductase activity
IC768_05025	COG0436	Aminotransferase
IC768_05045	COG3706	GGDEF domain
IC768_05050	COG0556	nucleotide-excision repair
IC768_05105	COG2070	2-Nitropropane dioxygenase
IC768_05120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC768_05135	COG1215	transferase activity, transferring glycosyl groups
IC768_05150	COG0415	Belongs to the DNA photolyase family
IC768_05160	COG1252	NADH dehydrogenase
IC768_05165	COG1686	Belongs to the peptidase S11 family
IC768_05180	COG1187	pseudouridine synthase activity
IC768_05265	COG5484	DNA packaging
IC768_05265	COG3728	DNA packaging
IC768_05375	COG0741	lytic transglycosylase activity
IC768_05375	COG1196	nuclear chromosome segregation
IC768_05375	COG0739	heme binding
IC768_05455	COG0477	Major facilitator Superfamily
IC768_05460	COG0583	DNA-binding transcription factor activity
IC768_05465	COG1823	symporter activity
IC768_05475	COG0612	Peptidase, M16
IC768_05500	COG0352	thiamine-phosphate diphosphorylase activity
IC768_05535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC768_05560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC768_05565	COG0076	glutamate decarboxylase activity
IC768_05575	COG1522	sequence-specific DNA binding
IC768_05580	COG3961	Belongs to the TPP enzyme family
IC768_05585	COG1113	amino acid transport
IC768_05590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC768_05595	COG0573	inorganic phosphate transmembrane transporter activity
IC768_05605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC768_05625	COG3647	Membrane
IC768_05650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC768_05655	COG1686	Belongs to the peptidase S11 family
IC768_05680	COG0583	DNA-binding transcription factor activity
IC768_05685	COG1067	ATP-dependent peptidase activity
IC768_05710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC768_05725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC768_05730	COG1966	Carbon starvation protein
IC768_05735	COG2879	small protein
IC768_05765	COG2814	Major facilitator Superfamily
IC768_05805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC768_05810	COG2423	ornithine cyclodeaminase activity
IC768_05825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC768_05835	COG1741	Belongs to the pirin family
IC768_05850	COG3739	integral membrane protein
IC768_05870	COG0302	gtp cyclohydrolase
IC768_05880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC768_05890	COG2840	Smr protein MutS2
IC768_05905	COG0512	Glutamine amidotransferase of anthranilate synthase
IC768_05920	COG0174	glutamine synthetase
IC768_05930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC768_05965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC768_05970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC768_05975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC768_05995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC768_06000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC768_06005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC768_06020	COG1960	acyl-CoA dehydrogenase activity
IC768_06025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC768_06030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC768_06040	COG2223	nitrite transmembrane transporter activity
IC768_06050	COG0024	Methionine aminopeptidase
IC768_06055	COG0052	Belongs to the universal ribosomal protein uS2 family
IC768_06070	COG2207	Transcriptional regulator
IC768_06095	COG2951	lytic endotransglycosylase activity
IC768_06100	COG0772	Belongs to the SEDS family
IC768_06115	COG0842	Transport permease protein
IC768_06120	COG1131	(ABC) transporter
IC768_06125	COG0582	viral genome integration into host DNA
IC768_06415	COG0582	viral genome integration into host DNA
IC768_06740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_06755	COG4215	(ABC) transporter
IC768_06760	COG4160	amino acid transport
IC768_06765	COG4598	ABC transporter
IC768_06775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC768_06780	COG0826	peptidase U32
IC768_06785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC768_06790	COG0384	phenazine biosynthesis protein PhzF
IC768_06800	COG1720	tRNA m6t6A37 methyltransferase activity
IC768_06825	COG0642	Histidine kinase
IC768_06845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC768_06850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC768_06855	COG3139	Protein of unknown function (DUF1315)
IC768_06865	COG1301	dicarboxylic acid transport
IC768_06870	COG1960	acyl-CoA dehydrogenase activity
IC768_06890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC768_06900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC768_06905	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC768_06925	COG1690	Belongs to the RtcB family
IC768_06930	COG1234	tRNA 3'-trailer cleavage
IC768_06935	COG4650	regulator
IC768_06960	COG2363	Small membrane protein
IC768_06980	COG0513	Belongs to the DEAD box helicase family
IC768_06990	COG0778	Nitroreductase
IC768_07050	COG1610	YqeY-like protein
IC768_07080	COG2815	serine threonine protein kinase
IC768_07080	COG0515	serine threonine protein kinase
IC768_07185	COG1335	isochorismatase
IC768_07190	COG0583	DNA-binding transcription factor activity
IC768_07210	COG0596	Alpha beta hydrolase
IC768_07220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC768_07230	COG0786	glutamate:sodium symporter activity
IC768_07235	COG0475	glutathione-regulated potassium exporter activity
IC768_07235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC768_07240	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_07315	COG1309	transcriptional regulator
IC768_07325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC768_07325	COG2169	Transcriptional regulator
IC768_07340	COG2985	domain, Protein
IC768_07365	COG2995	paraquat-inducible protein a
IC768_07370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC768_07370	COG3008	intermembrane lipid transfer
IC768_07380	COG2351	hydroxyisourate hydrolase activity
IC768_07395	COG5002	protein histidine kinase activity
IC768_07420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC768_07430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC768_07435	COG0642	Histidine kinase
IC768_07440	COG0745	RESPONSE REGULATOR receiver
IC768_07465	COG2175	clavaminate synthase activity
IC768_07470	COG3246	L-lysine catabolic process to acetate
IC768_07475	COG2814	Major facilitator Superfamily
IC768_07490	COG2855	membrane
IC768_07535	COG1301	dicarboxylic acid transport
IC768_07550	COG2011	ABC-type metal ion transport system permease component
IC768_07555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC768_07560	COG1464	Belongs to the NlpA lipoprotein family
IC768_07565	COG0151	Belongs to the GarS family
IC768_07570	COG0138	bifunctional purine biosynthesis protein purh
IC768_07575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC768_07605	COG2308	Evidence 4 Homologs of previously reported genes of
IC768_07615	COG1305	Transglutaminase-like
IC768_07625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC768_07630	COG0305	Participates in initiation and elongation during chromosome replication
IC768_07655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC768_07665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC768_07695	COG0726	polysaccharide deacetylase
IC768_07695	COG1649	PFAM Uncharacterised BCR, COG1649
IC768_07700	COG1215	transferase activity, transferring glycosyl groups
IC768_07705	COG3658	cytochrome
IC768_07715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_07735	COG2890	protein-(glutamine-N5) methyltransferase activity
IC768_07740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC768_07745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC768_07760	COG1960	acyl-CoA dehydrogenase activity
IC768_07765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC768_07770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC768_07795	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC768_07800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC768_07805	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC768_07810	COG2205	protein histidine kinase activity
IC768_07815	COG0745	RESPONSE REGULATOR receiver
IC768_07820	COG0174	glutamine synthetase
IC768_07840	COG0729	surface antigen
IC768_07870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC768_07875	COG2814	Major facilitator Superfamily
IC768_07885	COG0583	DNA-binding transcription factor activity
IC768_07900	COG1187	pseudouridine synthase activity
IC768_07920	COG0802	atpase or kinase
IC768_07925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC768_07935	COG1923	regulation of RNA biosynthetic process
IC768_07940	COG0697	spore germination
IC768_07965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC768_07970	COG0519	Catalyzes the synthesis of GMP from XMP
IC768_07970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC768_07975	COG4302	ethanolamine ammonia-lyase activity
IC768_07980	COG4303	Ethanolamine ammonia lyase large subunit
IC768_07985	COG0531	amino acid
IC768_08005	COG1454	alcohol dehydrogenase
IC768_08010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC768_08020	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC768_08040	COG0308	aminopeptidase N
IC768_08070	COG0625	glutathione transferase activity
IC768_08085	COG1605	Chorismate mutase
IC768_08135	COG4264	IucA IucC family
IC768_08145	COG4264	IucA IucC family
IC768_08150	COG2423	ornithine cyclodeaminase activity
IC768_08155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC768_08165	COG0668	transmembrane transport
IC768_08210	COG0488	(ABC) transporter
IC768_08215	COG0589	response to stress
IC768_08240	COG3135	benzoate transporter
IC768_08245	COG1522	sequence-specific DNA binding
IC768_08255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC768_08260	COG0583	DNA-binding transcription factor activity
IC768_08270	COG0183	Belongs to the thiolase family
IC768_08275	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_08280	COG2030	dehydratase
IC768_08285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC768_08310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC768_08325	COG0824	Thioesterase
IC768_08330	COG1454	alcohol dehydrogenase
IC768_08340	COG1335	isochorismatase
IC768_08355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC768_08385	COG0069	glutamate synthase activity
IC768_08430	COG2814	Major facilitator Superfamily
IC768_08445	COG0511	ligase activity, forming carbon-carbon bonds
IC768_08465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC768_08465	COG1116	anion transmembrane transporter activity
IC768_08470	COG0745	RESPONSE REGULATOR receiver
IC768_08480	COG2146	nitrite reductase [NAD(P)H] activity
IC768_08480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC768_08485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC768_08490	COG0243	molybdopterin cofactor binding
IC768_08500	COG0243	molybdopterin cofactor binding
IC768_08505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC768_08520	COG0315	cyclic pyranopterin monophosphate synthase activity
IC768_08520	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC768_08525	COG0303	'Molybdopterin
IC768_08540	COG0697	spore germination
IC768_08560	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC768_08565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC768_08620	COG2204	response regulator
IC768_08625	COG3852	Histidine kinase
IC768_08650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC768_08655	COG0575	Belongs to the CDS family
IC768_08670	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC768_08690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC768_08705	COG2137	regulation of response to DNA damage stimulus
IC768_08715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC768_08720	COG1011	Hydrolase
IC768_08735	COG1522	sequence-specific DNA binding
IC768_08745	COG1113	amino acid transport
IC768_08760	COG0659	secondary active sulfate transmembrane transporter activity
IC768_08775	COG5001	Diguanylate cyclase
IC768_08775	COG3300	MHYT domain
IC768_08795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC768_08795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC768_08795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC768_08800	COG1105	Belongs to the carbohydrate kinase PfkB family
IC768_08805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC768_08805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC768_08835	COG0024	Methionine aminopeptidase
IC768_08840	COG0583	DNA-binding transcription factor activity
IC768_08850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC768_08855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC768_08860	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC768_08885	COG0552	protein localization to endoplasmic reticulum
IC768_08910	COG4890	Cyd operon protein YbgT
IC768_08915	COG1294	oxidase, subunit
IC768_08930	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC768_08940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC768_08945	COG4774	siderophore transport
IC768_08960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC768_08965	COG0569	domain protein
IC768_08970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC768_09000	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC768_09005	COG0542	response to heat
IC768_09030	COG1902	pentaerythritol trinitrate reductase activity
IC768_09030	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC768_09070	COG0148	phosphopyruvate hydratase activity
IC768_09075	COG2323	membrane
IC768_09085	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC768_09095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC768_09100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC768_09105	COG0183	Belongs to the thiolase family
IC768_09110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC768_09115	COG0596	Alpha beta hydrolase
IC768_09120	COG2271	Major facilitator Superfamily
IC768_09125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC768_09130	COG3485	protocatechuate 3,4-dioxygenase
IC768_09135	COG3485	protocatechuate 3,4-dioxygenase
IC768_09145	COG3420	alginic acid biosynthetic process
IC768_09150	COG3659	wide pore channel activity
IC768_09155	COG4993	Dehydrogenase
IC768_09165	COG2391	methyltransferase activity
IC768_09180	COG1414	Transcriptional regulator
IC768_09185	COG0583	DNA-binding transcription factor activity
IC768_09190	COG1960	acyl-CoA dehydrogenase activity
IC768_09215	COG2814	Major facilitator Superfamily
IC768_09225	COG0154	amidase activity
IC768_09245	COG4638	Rieske (2fe-2S)
IC768_09255	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_09265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC768_09275	COG3733	amine oxidase
IC768_09290	COG1012	belongs to the aldehyde dehydrogenase family
IC768_09295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC768_09300	COG0183	Belongs to the thiolase family
IC768_09305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC768_09310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC768_09320	COG4829	muconolactone delta-isomerase
IC768_09325	COG4948	Mandelate Racemase Muconate Lactonizing
IC768_09330	COG0583	DNA-binding transcription factor activity
IC768_09360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC768_09385	COG1309	transcriptional regulator
IC768_09470	COG2188	Transcriptional regulator
IC768_09485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC768_09500	COG2271	Major facilitator Superfamily
IC768_09510	COG1566	PFAM secretion protein HlyD family protein
IC768_09540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC768_09545	COG1120	ATPase activity
IC768_09565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC768_09685	COG2175	clavaminate synthase activity
IC768_09690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC768_09705	COG0667	Aldo Keto reductase
IC768_09710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_09725	COG2175	clavaminate synthase activity
IC768_09755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC768_09760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_09765	COG4771	TonB-dependent receptor
IC768_09795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_09800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC768_09805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC768_09810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC768_09825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC768_09830	COG0805	protein transport
IC768_09840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_09860	COG1132	(ABC) transporter
IC768_09865	COG1132	(ABC) transporter
IC768_09885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC768_09890	COG0601	transmembrane transport
IC768_09920	COG3539	Fimbrial protein
IC768_09945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC768_09955	COG0753	catalase activity
IC768_09965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC768_09970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC768_09980	COG2205	protein histidine kinase activity
IC768_09985	COG0745	RESPONSE REGULATOR receiver
IC768_09990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_09995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_10055	COG4771	TonB-dependent receptor
IC768_10060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_10065	COG1535	isochorismatase
IC768_10065	COG3433	isochorismatase activity
IC768_10070	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC768_10075	COG1169	isochorismate synthase
IC768_10080	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_10090	COG3251	PFAM MbtH domain protein
IC768_10095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC768_10120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC768_10125	COG4149	molybdate abc transporter
IC768_10130	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC768_10140	COG4638	Rieske (2fe-2S)
IC768_10145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC768_10150	COG0543	2 iron, 2 sulfur cluster binding
IC768_10150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC768_10165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC768_10175	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_10195	COG2207	Transcriptional regulator
IC768_10200	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_10205	COG2610	gluconate transmembrane transporter activity
IC768_10210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC768_10240	COG2814	Major facilitator Superfamily
IC768_10265	COG0583	DNA-binding transcription factor activity
IC768_10290	COG2031	fatty acid transporter
IC768_10295	COG0183	Belongs to the thiolase family
IC768_10300	COG0583	DNA-binding transcription factor activity
IC768_10305	COG0583	DNA-binding transcription factor activity
IC768_10320	COG1027	Aspartate ammonia-lyase
IC768_10330	COG0477	Major facilitator Superfamily
IC768_10340	COG3708	Transcriptional regulator
IC768_10340	COG2207	Transcriptional regulator
IC768_10355	COG0730	response to heat
IC768_10365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC768_10365	COG3453	Protein conserved in bacteria
IC768_10375	COG3781	membrane
IC768_10380	COG1063	alcohol dehydrogenase
IC768_10390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC768_10395	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC768_10400	COG0022	dehydrogenase e1 component
IC768_10405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC768_10410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC768_10425	COG3706	GGDEF domain
IC768_10440	COG0133	tryptophan synthase activity
IC768_10450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC768_10485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC768_10510	COG2226	methyltransferase
IC768_10560	COG0842	Transport permease protein
IC768_10565	COG0842	Transport permease protein
IC768_10570	COG1131	(ABC) transporter
IC768_10585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC768_10610	COG0730	response to heat
IC768_10615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC768_10630	COG0406	alpha-ribazole phosphatase activity
IC768_10635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC768_10650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC768_10655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC768_10670	COG1960	acyl-CoA dehydrogenase activity
IC768_10675	COG1960	acyl-CoA dehydrogenase activity
IC768_10680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_10685	COG2207	Transcriptional regulator
IC768_10690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC768_10695	COG0776	regulation of translation
IC768_10720	COG0822	iron-sulfur transferase activity
IC768_10725	COG0316	Belongs to the HesB IscA family
IC768_10755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC768_10775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC768_10780	COG0702	epimerase
IC768_10810	COG4172	Belongs to the ABC transporter superfamily
IC768_10815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC768_10820	COG0601	transmembrane transport
IC768_10845	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC768_10870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC768_10990	COG4695	Portal protein
IC768_11070	COG0305	Participates in initiation and elongation during chromosome replication
IC768_11090	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC768_11135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC768_11150	COG2431	L-lysine efflux transmembrane transporter activity
IC768_11165	COG0776	regulation of translation
IC768_11230	COG0084	hydrolase, TatD family'
IC768_11255	COG1132	(ABC) transporter
IC768_11265	COG0811	peptide transport
IC768_11270	COG1475	DNA binding
IC768_11275	COG1192	Involved in chromosome partitioning
IC768_11285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC768_11325	COG0424	maF-like protein
IC768_11330	COG2850	peptidyl-arginine hydroxylation
IC768_11350	COG3619	membrane
IC768_11355	COG3122	Protein conserved in bacteria
IC768_11360	COG1132	(ABC) transporter
IC768_11380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC768_11385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC768_11395	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC768_11395	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC768_11395	COG0506	proline dehydrogenase activity
IC768_11400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC768_11415	COG3698	Phosphodiester glycosidase
IC768_11425	COG2353	YceI-like domain
IC768_11440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC768_11480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC768_11480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC768_11505	COG3539	Fimbrial protein
IC768_11510	COG3121	Chaperone
IC768_11530	COG0697	spore germination
IC768_11540	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC768_11550	COG0583	DNA-binding transcription factor activity
IC768_11570	COG2197	response regulator
IC768_11595	COG1522	sequence-specific DNA binding
IC768_11605	COG1126	abc transporter atp-binding protein
IC768_11610	COG0765	amino acid transport
IC768_11615	COG0765	amino acid transport
IC768_11645	COG1464	Belongs to the NlpA lipoprotein family
IC768_11655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC768_11660	COG2011	ABC-type metal ion transport system permease component
IC768_11665	COG0012	GTP binding
IC768_11690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC768_11725	COG1917	Cupin 2, conserved barrel domain protein
IC768_11725	COG2207	Transcriptional regulator
IC768_11730	COG0386	Belongs to the glutathione peroxidase family
IC768_11740	COG0436	Aminotransferase
IC768_11745	COG1301	dicarboxylic acid transport
IC768_11780	COG3634	alkyl hydroperoxide reductase activity
IC768_11795	COG0583	DNA-binding transcription factor activity
IC768_11800	COG0431	NADPH-dependent FMN reductase
IC768_11805	COG0798	PFAM Bile acid sodium symporter
IC768_11810	COG0640	Transcriptional regulator
IC768_11825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC768_11835	COG0583	DNA-binding transcription factor activity
IC768_11845	COG1953	Uracil, thiamine, allantoin
IC768_11855	COG2175	clavaminate synthase activity
IC768_11860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC768_11865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC768_11870	COG4521	taurine ABC transporter
IC768_11880	COG0477	Major facilitator Superfamily
IC768_11900	COG1271	oxidase subunit
IC768_11905	COG1294	oxidase, subunit
IC768_11915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC768_11935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC768_11955	COG3052	prosthetic group binding
IC768_11960	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC768_11985	COG1346	cytolysis
IC768_11995	COG0583	DNA-binding transcription factor activity
IC768_12000	COG0625	glutathione transferase activity
IC768_12005	COG0625	glutathione transferase activity
IC768_12010	COG0583	DNA-binding transcription factor activity
IC768_12025	COG1045	serine acetyltransferase
IC768_12030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC768_12035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC768_12040	COG1280	lysine exporter protein (LysE YggA)
IC768_12050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC768_12055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC768_12065	COG0765	amino acid transport
IC768_12070	COG0765	amino acid transport
IC768_12110	COG2205	protein histidine kinase activity
IC768_12110	COG0784	Response regulator, receiver
IC768_12130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC768_12150	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_12195	COG0583	DNA-binding transcription factor activity
IC768_12215	COG0318	PFAM AMP-dependent synthetase and ligase
IC768_12220	COG1309	transcriptional regulator
IC768_12225	COG1960	acyl-CoA dehydrogenase activity
IC768_12230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC768_12235	COG1024	Enoyl-CoA hydratase
IC768_12240	COG4770	biotin carboxylase activity
IC768_12250	COG0583	DNA-binding transcription factor activity
IC768_12265	COG1960	acyl-CoA dehydrogenase activity
IC768_12275	COG2814	Major facilitator Superfamily
IC768_12285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC768_12290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC768_12295	COG2814	Major facilitator Superfamily
IC768_12300	COG1960	acyl-CoA dehydrogenase activity
IC768_12305	COG1024	Enoyl-CoA hydratase
IC768_12310	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_12315	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC768_12320	COG0183	Belongs to the thiolase family
IC768_12330	COG2814	Major facilitator Superfamily
IC768_12345	COG1024	Enoyl-CoA hydratase
IC768_12355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC768_12360	COG1960	acyl-CoA dehydrogenase activity
IC768_12365	COG2814	Major facilitator Superfamily
IC768_12370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC768_12375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC768_12395	COG1840	ABC-type Fe3 transport system, periplasmic component
IC768_12410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC768_12415	COG1414	Transcriptional regulator
IC768_12425	COG0583	DNA-binding transcription factor activity
IC768_12440	COG3038	cytochrome b561
IC768_12445	COG0753	catalase activity
IC768_12450	COG0531	amino acid
IC768_12455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC768_12470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC768_12475	COG1309	transcriptional regulator
IC768_12515	COG3179	chitinase
IC768_12535	COG0406	alpha-ribazole phosphatase activity
IC768_12545	COG2050	protein possibly involved in aromatic compounds catabolism
IC768_12555	COG3327	negative regulation of DNA-templated transcription, initiation
IC768_12560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC768_12570	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC768_12575	COG1024	Enoyl-CoA hydratase
IC768_12580	COG1024	Enoyl-CoA hydratase
IC768_12585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC768_12590	COG2151	metal-sulfur cluster biosynthetic enzyme
IC768_12595	COG3396	Phenylacetate-CoA oxygenase
IC768_12600	COG3460	Phenylacetate-CoA oxygenase
IC768_12605	COG3396	Phenylacetate-CoA oxygenase
IC768_12610	COG2030	dehydratase
IC768_12610	COG1012	belongs to the aldehyde dehydrogenase family
IC768_12615	COG1760	l-serine dehydratase
IC768_12625	COG0789	Transcriptional regulator
IC768_12635	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC768_12640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC768_12655	COG2807	transmembrane transport
IC768_12660	COG0590	tRNA wobble adenosine to inosine editing
IC768_12765	COG0477	Major facilitator Superfamily
IC768_12780	COG1116	anion transmembrane transporter activity
IC768_12785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC768_12795	COG0864	Transcriptional regulator
IC768_12810	COG1733	regulation of RNA biosynthetic process
IC768_12815	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC768_12820	COG0439	Biotin carboxylase
IC768_12835	COG1063	alcohol dehydrogenase
IC768_12885	COG0038	chloride channel
IC768_12890	COG4770	biotin carboxylase activity
IC768_12910	COG1914	H( )-stimulated, divalent metal cation uptake system
IC768_12915	COG0583	DNA-binding transcription factor activity
IC768_12925	COG1595	DNA-templated transcription, initiation
IC768_12935	COG3220	belongs to the UPF0276 family
IC768_12950	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_12965	COG2076	Multidrug Resistance protein
IC768_12980	COG3713	MltA-interacting MipA family protein
IC768_12985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC768_13030	COG3209	COG3209 Rhs family protein
IC768_13110	COG1309	transcriptional regulator
IC768_13115	COG1278	Cold shock
IC768_13130	COG1522	sequence-specific DNA binding
IC768_13140	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_13150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC768_13155	COG4774	siderophore transport
IC768_13175	COG2814	Major facilitator Superfamily
IC768_13190	COG0402	S-adenosylhomocysteine deaminase activity
IC768_13195	COG0583	DNA-binding transcription factor activity
IC768_13205	COG1271	oxidase subunit
IC768_13210	COG1294	oxidase, subunit
IC768_13215	COG1469	GTP cyclohydrolase I activity
IC768_13235	COG1560	Kdo2-lipid A biosynthetic process
IC768_13280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC768_13290	COG4122	O-methyltransferase activity
IC768_13320	COG1538	Outer membrane efflux protein
IC768_13325	COG1137	ATPase activity
IC768_13330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC768_13340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC768_13345	COG0517	IMP dehydrogenase activity
IC768_13345	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC768_13365	COG0667	Aldo Keto reductase
IC768_13375	COG2814	Major facilitator Superfamily
IC768_13405	COG1278	Cold shock
IC768_13410	COG1280	lysine exporter protein (LysE YggA)
IC768_13445	COG1570	exodeoxyribonuclease VII activity
IC768_13530	COG2871	sodium ion transport
IC768_13540	COG0583	DNA-binding transcription factor activity
IC768_13550	COG4638	Rieske (2fe-2S)
IC768_13555	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC768_13560	COG0633	Ferredoxin
IC768_13560	COG0543	2 iron, 2 sulfur cluster binding
IC768_13565	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_13570	COG3135	benzoate transporter
IC768_13575	COG2814	Major facilitator Superfamily
IC768_13590	COG1643	Atp-dependent helicase
IC768_13605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_13625	COG3634	alkyl hydroperoxide reductase activity
IC768_13645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC768_13650	COG0625	glutathione transferase activity
IC768_13695	COG0542	response to heat
IC768_13710	COG1765	OsmC-like protein
IC768_13720	COG0667	Aldo Keto reductase
IC768_13735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC768_13750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC768_13760	COG0527	aspartate kinase activity
IC768_13770	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC768_13780	COG3038	cytochrome b561
IC768_13785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC768_13790	COG2252	PERMEase
IC768_13800	COG2072	flavoprotein involved in K transport
IC768_13815	COG1741	Belongs to the pirin family
IC768_13820	COG1309	transcriptional regulator
IC768_13835	COG2072	flavoprotein involved in K transport
IC768_13840	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC768_13845	COG0583	DNA-binding transcription factor activity
IC768_13860	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC768_13890	COG1944	ATP diphosphatase activity
IC768_13910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC768_13925	COG2814	Major facilitator Superfamily
IC768_13930	COG1024	Enoyl-CoA hydratase
IC768_13935	COG1012	belongs to the aldehyde dehydrogenase family
IC768_13945	COG1960	acyl-CoA dehydrogenase activity
IC768_13965	COG0697	spore germination
IC768_13985	COG1113	amino acid transport
IC768_14005	COG1012	belongs to the aldehyde dehydrogenase family
IC768_14025	COG0531	amino acid
IC768_14035	COG1113	amino acid transport
IC768_14085	COG1846	Transcriptional regulator
IC768_14135	COG4269	membrane
IC768_14155	COG0583	DNA-binding transcription factor activity
IC768_14165	COG0251	oxidation-reduction process
IC768_14185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC768_14215	COG3152	Membrane
IC768_14265	COG0582	viral genome integration into host DNA
IC768_14275	COG1902	pentaerythritol trinitrate reductase activity
IC768_14275	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC768_14285	COG3706	GGDEF domain
IC768_14285	COG2203	Gaf domain
IC768_14285	COG5001	Diguanylate cyclase
IC768_14285	COG4251	negative regulation of phosphorylation
IC768_14295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC768_14320	COG4172	Belongs to the ABC transporter superfamily
IC768_14325	COG4239	(ABC) transporter, permease
IC768_14330	COG4174	ABC transporter (Permease)
IC768_14340	COG1388	LysM domain
IC768_14340	COG0741	lytic transglycosylase activity
IC768_14385	COG0583	DNA-binding transcription factor activity
IC768_14410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC768_14415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC768_14420	COG0006	proline dipeptidase activity
IC768_14455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC768_14560	COG0681	Belongs to the peptidase S26 family
IC768_14595	COG4373	Mu-like prophage FluMu protein gp28
IC768_14605	COG4383	Mu-like prophage protein gp29
IC768_14610	COG2369	cell adhesion
IC768_14630	COG4397	Mu-like prophage major head subunit gpT
IC768_14750	COG3384	dioxygenase
IC768_14760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC768_14765	COG2878	Part of a membrane complex involved in electron transport
IC768_14770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC768_14795	COG0768	penicillin binding
IC768_14800	COG0742	ribosomal rna small subunit methyltransferase
IC768_14820	COG0830	nickel cation binding
IC768_14830	COG0804	urea catabolic process
IC768_14870	COG1253	flavin adenine dinucleotide binding
IC768_14875	COG2851	Citrate transporter
IC768_14925	COG1773	rubredoxin
IC768_14930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC768_14940	COG0583	DNA-binding transcription factor activity
IC768_14965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC768_14970	COG4181	ATPase activity
IC768_15015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC768_15035	COG0306	phosphate transporter
IC768_15070	COG2223	nitrite transmembrane transporter activity
IC768_15075	COG2207	Transcriptional regulator
IC768_15080	COG2066	Belongs to the glutaminase family
IC768_15085	COG0242	peptide deformylase activity
IC768_15090	COG0477	Major facilitator Superfamily
IC768_15100	COG0028	Belongs to the TPP enzyme family
IC768_15115	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_15120	COG2267	carboxylic ester hydrolase activity
IC768_15130	COG2271	Major facilitator Superfamily
IC768_15165	COG1414	Transcriptional regulator
IC768_15195	COG1024	Enoyl-CoA hydratase
IC768_15205	COG1215	transferase activity, transferring glycosyl groups
IC768_15210	COG0726	polysaccharide deacetylase
IC768_15210	COG1649	PFAM Uncharacterised BCR, COG1649
IC768_15220	COG4681	YaeQ
IC768_15230	COG0523	cobalamin synthesis protein
IC768_15240	COG1607	acyl-coa hydrolase
IC768_15250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC768_15255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC768_15260	COG1309	transcriptional regulator
IC768_15285	COG2040	homocysteine
IC768_15290	COG0531	amino acid
IC768_15310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC768_15315	COG0477	Major facilitator Superfamily
IC768_15350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC768_15355	COG3586	endonuclease activity
IC768_15415	COG0405	Gamma-glutamyltransferase
IC768_15420	COG2814	Major facilitator Superfamily
IC768_15430	COG2050	protein possibly involved in aromatic compounds catabolism
IC768_15445	COG1090	epimerase
IC768_15465	COG0420	3'-5' exonuclease activity
IC768_15475	COG1968	undecaprenyl-diphosphatase activity
IC768_15495	COG0735	belongs to the Fur family
IC768_15500	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC768_15505	COG2914	Belongs to the UPF0125 (RnfH) family
IC768_15520	COG0121	glutamine amidotransferase
IC768_15535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC768_15545	COG0210	DNA helicase
IC768_15550	COG2885	chlorophyll binding
IC768_15555	COG0204	Acyl-transferase
IC768_15570	COG2894	cell division
IC768_15585	COG1280	lysine exporter protein (LysE YggA)
IC768_15590	COG1674	ftsk spoiiie
IC768_15595	COG0492	ferredoxin-NADP+ reductase activity
IC768_15600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC768_15610	COG0456	acetyltransferase
IC768_15630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC768_15640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC768_15655	COG1981	membrane
IC768_15665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC768_15665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC768_15685	COG1012	belongs to the aldehyde dehydrogenase family
IC768_15690	COG4638	Rieske (2fe-2S)
IC768_15695	COG0657	acetylesterase activity
IC768_15705	COG0473	3-isopropylmalate dehydrogenase activity
IC768_15710	COG0583	DNA-binding transcription factor activity
IC768_15730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC768_15755	COG0564	pseudouridine synthase activity
IC768_15765	COG0358	DNA primase activity
IC768_15780	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC768_15810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC768_15840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC768_15850	COG0351	phosphomethylpyrimidine kinase
IC768_15850	COG0352	thiamine-phosphate diphosphorylase activity
IC768_15850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC768_15855	COG1652	LysM domain
IC768_15880	COG1399	metal-binding, possibly nucleic acid-binding protein
IC768_15885	COG3101	peptidyl-lysine hydroxylation
IC768_15890	COG0009	L-threonylcarbamoyladenylate synthase
IC768_15895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC768_15900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC768_15915	COG4106	trans-aconitate 2-methyltransferase activity
IC768_15930	COG0596	Alpha beta hydrolase
IC768_15930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC768_15930	COG2226	methyltransferase
IC768_15935	COG1877	trehalose-phosphatase activity
IC768_15940	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC768_15945	COG2223	nitrite transmembrane transporter activity
IC768_15965	COG1196	nuclear chromosome segregation
IC768_15975	COG0730	response to heat
IC768_15990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC768_16000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC768_16045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC768_16050	COG0489	protein tyrosine kinase activity
IC768_16060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC768_16060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC768_16095	COG2081	HI0933 family
IC768_16105	COG0668	transmembrane transport
IC768_16125	COG0583	DNA-binding transcription factor activity
IC768_16150	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC768_16155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC768_16170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC768_16185	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC768_16210	COG3706	GGDEF domain
IC768_16225	COG0745	RESPONSE REGULATOR receiver
IC768_16245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC768_16275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC768_16280	COG0583	DNA-binding transcription factor activity
IC768_16325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC768_16340	COG0583	DNA-binding transcription factor activity
IC768_16350	COG0583	DNA-binding transcription factor activity
IC768_16365	COG0583	DNA-binding transcription factor activity
IC768_16370	COG1053	succinate dehydrogenase
IC768_16385	COG1309	transcriptional regulator
IC768_16395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC768_16400	COG2814	Major facilitator Superfamily
IC768_16405	COG1960	acyl-CoA dehydrogenase activity
IC768_16410	COG0583	DNA-binding transcription factor activity
IC768_16415	COG1063	alcohol dehydrogenase
IC768_16445	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC768_16450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC768_16455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC768_16475	COG2132	Multicopper oxidase
IC768_16485	COG0561	phosphatase activity
IC768_16490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC768_16500	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC768_16515	COG1214	PFAM Peptidase M22, glycoprotease
IC768_16565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC768_16575	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC768_16580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC768_16585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC768_16645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC768_16655	COG1846	Transcriptional regulator
IC768_16660	COG1764	response to oxidative stress
IC768_16700	COG0037	tRNA processing
IC768_16710	COG0248	Ppx GppA phosphatase
IC768_16740	COG0072	phenylalanine-tRNA ligase activity
IC768_16770	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC768_16780	COG1238	metal cluster binding
IC768_16785	COG0625	glutathione transferase activity
IC768_16800	COG0318	PFAM AMP-dependent synthetase and ligase
IC768_16805	COG3028	Belongs to the UPF0307 family
IC768_16830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC768_16835	COG0617	tRNA 3'-terminal CCA addition
IC768_16840	COG1555	photosystem II stabilization
IC768_16845	COG3956	TIGRFAM MazG family protein
IC768_16855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC768_16875	COG0784	Response regulator, receiver
IC768_16875	COG5002	protein histidine kinase activity
IC768_16875	COG2205	protein histidine kinase activity
IC768_16880	COG1024	Enoyl-CoA hydratase
IC768_16885	COG2084	Dehydrogenase
IC768_16890	COG3622	Belongs to the hyi family
IC768_16925	COG0697	spore germination
IC768_16935	COG2814	Major facilitator Superfamily
IC768_16960	COG1230	cation diffusion facilitator family transporter
IC768_16975	COG2814	Major facilitator Superfamily
IC768_17080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC768_17090	COG0583	DNA-binding transcription factor activity
IC768_17100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC768_17110	COG0084	hydrolase, TatD family'
IC768_17125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC768_17150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC768_17155	COG0440	acetolactate synthase activity
IC768_17160	COG0028	Belongs to the TPP enzyme family
IC768_17185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC768_17190	COG0577	efflux transmembrane transporter activity
IC768_17190	COG1136	(ABC) transporter
IC768_17195	COG1538	Outer membrane efflux protein
IC768_17210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC768_17215	COG1162	GTPase activity
IC768_17225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC768_17265	COG1426	Protein conserved in bacteria
IC768_17300	COG0793	Belongs to the peptidase S41A family
IC768_17315	COG2267	carboxylic ester hydrolase activity
IC768_17325	COG1012	belongs to the aldehyde dehydrogenase family
IC768_17330	COG3265	gluconokinase activity
IC768_17340	COG0800	Aldolase
IC768_17350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC768_17355	COG0857	belongs to the CobB CobQ family
IC768_17355	COG0280	phosphate acetyltransferase
IC768_17360	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC768_17360	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC768_17380	COG0740	serine-type endopeptidase activity
IC768_17390	COG4774	siderophore transport
IC768_17400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC768_17410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC768_17410	COG2813	Specifically methylates the guanine in position
IC768_17505	COG0788	formyltetrahydrofolate deformylase activity
IC768_17530	COG4651	solute:proton antiporter activity
IC768_17530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC768_17550	COG0724	RNA recognition motif
IC768_17555	COG0210	DNA helicase
IC768_17580	COG1733	regulation of RNA biosynthetic process
IC768_17590	COG2900	Belongs to the SlyX family
IC768_17595	COG0488	(ABC) transporter
IC768_17605	COG1280	lysine exporter protein (LysE YggA)
IC768_17610	COG1560	Kdo2-lipid A biosynthetic process
IC768_17620	COG1301	dicarboxylic acid transport
IC768_17675	COG0473	3-isopropylmalate dehydrogenase activity
IC768_17700	COG0583	DNA-binding transcription factor activity
IC768_17745	COG0583	DNA-binding transcription factor activity
IC768_17755	COG0625	glutathione transferase activity
IC768_17760	COG2378	regulation of single-species biofilm formation
IC768_17775	COG1530	ribonuclease E activity
IC768_17780	COG0318	PFAM AMP-dependent synthetase and ligase
IC768_17795	COG0583	DNA-binding transcription factor activity
IC768_17800	COG4221	oxidoreductase activity
IC768_17805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC768_17815	COG0534	Mate efflux family protein
IC768_17830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC768_17860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC768_17860	COG0493	'glutamate synthase
IC768_17870	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC768_17875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC768_17890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC768_17900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC768_17900	COG0644	oxidoreductase
IC768_17915	COG4535	Mg2 and Co2 transporter CorC
IC768_17925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC768_17950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC768_17955	COG0475	glutathione-regulated potassium exporter activity
IC768_17955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC768_17960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC768_17975	COG0789	Transcriptional regulator
IC768_17980	COG0598	Magnesium transport protein CorA
IC768_17985	COG1185	polyribonucleotide nucleotidyltransferase activity
IC768_17995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC768_18000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC768_18005	COG1074	ATP-dependent DNA helicase activity
IC768_18010	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC768_18035	COG2226	methyltransferase
IC768_18050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC768_18065	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC768_18080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC768_18080	COG2111	Na H antiporter
IC768_18085	COG1006	Multisubunit Na H antiporter MnhC subunit
IC768_18090	COG0651	ATP synthesis coupled electron transport
IC768_18095	COG1863	multisubunit Na H antiporter MnhE subunit
IC768_18100	COG2212	antiporter activity
IC768_18105	COG1320	monovalent cation:proton antiporter activity
IC768_18110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC768_18120	COG0195	Participates in both transcription termination and antitermination
IC768_18170	COG0237	dephospho-CoA kinase activity
IC768_18180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC768_18190	COG0497	DNA recombination
IC768_18200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC768_18215	COG1289	transmembrane transporter activity
IC768_18230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC768_18290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC768_18305	COG0326	Molecular chaperone. Has ATPase activity
IC768_18320	COG2056	Na+-H+ antiporter family
IC768_18325	COG0596	Alpha beta hydrolase
IC768_18420	COG0546	phosphoglycolate phosphatase activity
IC768_18425	COG1716	ATPase activity
IC768_18470	COG0181	hydroxymethylbilane synthase activity
IC768_18480	COG3275	phosphorelay sensor kinase activity
IC768_18500	COG1538	Outer membrane efflux protein
IC768_18510	COG0697	spore germination
IC768_18530	COG0494	nUDIX hydrolase
IC768_18540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC768_18545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC768_18575	COG4974	Belongs to the 'phage' integrase family
IC768_18580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC768_18590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC768_18600	COG2197	response regulator
IC768_18615	COG0793	Belongs to the peptidase S41A family
IC768_18620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC768_18625	COG0795	lipopolysaccharide-transporting ATPase activity
IC768_18630	COG0795	lipopolysaccharide-transporting ATPase activity
IC768_18665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC768_18665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC768_18675	COG0004	ammonium transporteR
IC768_18680	COG0347	Belongs to the P(II) protein family
IC768_18690	COG0606	chelatase, subunit chli
IC768_18695	COG0431	NADPH-dependent FMN reductase
IC768_18700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC768_18705	COG0235	Class ii aldolase
IC768_18710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC768_18725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC768_18740	COG0318	PFAM AMP-dependent synthetase and ligase
IC768_18750	COG0477	Major facilitator Superfamily
IC768_18755	COG2860	membrane
IC768_18765	COG1253	flavin adenine dinucleotide binding
IC768_18775	COG2814	Major facilitator Superfamily
IC768_18785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC768_18820	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC768_18835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC768_18870	COG1309	transcriptional regulator
IC768_18905	COG0758	DNA mediated transformation
IC768_18915	COG0697	spore germination
IC768_18920	COG1309	transcriptional regulator
IC768_18935	COG0386	Belongs to the glutathione peroxidase family
IC768_18945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC768_18950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC768_19000	COG1121	(ABC) transporter
IC768_19005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC768_19010	COG1280	lysine exporter protein (LysE YggA)
IC768_19015	COG2837	iron assimilation
IC768_19025	COG0281	malic enzyme
IC768_19060	COG0735	belongs to the Fur family
IC768_19070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC768_19075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC768_19075	COG0519	Catalyzes the synthesis of GMP from XMP
IC768_19080	COG4399	Belongs to the UPF0754 family
IC768_19085	COG2259	Doxx family
IC768_19090	COG0586	Pfam SNARE associated Golgi protein
IC768_19105	COG1192	Involved in chromosome partitioning
IC768_19115	COG0271	Belongs to the BolA IbaG family
IC768_19155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC768_19155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC768_19155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC768_19155	COG3321	synthase
IC768_19160	COG1960	acyl-CoA dehydrogenase activity
IC768_19170	COG2197	response regulator
IC768_19180	COG3916	Acyl-homoserine-lactone synthase
IC768_19190	COG1024	Enoyl-CoA hydratase
IC768_19195	COG1024	Enoyl-CoA hydratase
IC768_19200	COG1960	acyl-CoA dehydrogenase activity
IC768_19205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC768_19225	COG1113	amino acid transport
IC768_19230	COG1113	amino acid transport
IC768_19235	COG0251	oxidation-reduction process
IC768_19275	COG0564	pseudouridine synthase activity
IC768_19345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC768_19360	COG1802	Transcriptional regulator
IC768_19370	COG1448	Aminotransferase
IC768_19375	COG0277	FAD linked oxidase domain protein
IC768_19385	COG2186	Transcriptional regulator
IC768_19395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC768_19415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC768_19420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC768_19435	COG0110	maltose O-acetyltransferase activity
IC768_19440	COG0463	Glycosyl transferase, family 2
IC768_19440	COG1216	Glycosyl transferase, family 2
IC768_19475	COG1086	Polysaccharide biosynthesis protein
IC768_19485	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC768_19490	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC768_19500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC768_19505	COG1596	polysaccharide export
IC768_19530	COG0728	peptidoglycan biosynthetic process
IC768_19535	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC768_19590	COG0546	phosphoglycolate phosphatase activity
IC768_19595	COG1028	Short-chain dehydrogenase reductase Sdr
IC768_19610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC768_19610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC768_19615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC768_19620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC768_19625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC768_19630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC768_19635	COG1116	anion transmembrane transporter activity
IC768_19640	COG1309	transcriptional regulator
IC768_19645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC768_19655	COG0196	riboflavin kinase activity
IC768_19660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC768_19670	COG1047	Peptidyl-prolyl cis-trans
IC768_19710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC768_19715	COG0657	acetylesterase activity
IC768_19765	COG2951	lytic endotransglycosylase activity
IC768_19770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC768_19785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC768_19795	COG0671	phosphoesterase, PA-phosphatase related
IC768_19800	COG0861	Integral membrane protein TerC family
IC768_19810	COG0754	glutathionylspermidine amidase activity
IC768_19820	COG0402	S-adenosylhomocysteine deaminase activity
IC768_19835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC768_19885	COG2217	Heavy metal translocating P-type atpase
IC768_19890	COG3174	membrane
IC768_19895	COG2205	protein histidine kinase activity
IC768_19910	COG2132	Multicopper oxidase
IC768_19935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC768_19975	COG0789	Transcriptional regulator
IC768_20130	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC768_20170	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC768_20175	COG0659	secondary active sulfate transmembrane transporter activity
IC768_20190	COG3328	transposase activity
IC768_20195	COG0583	DNA-binding transcription factor activity
IC768_20200	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC768_20205	COG0604	alcohol dehydrogenase
IC768_20205	COG3321	synthase
IC768_20215	COG0697	spore germination
IC768_20220	COG0477	Major facilitator Superfamily
IC768_20250	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC768_20265	COG1979	alcohol dehydrogenase
IC768_20275	COG1902	pentaerythritol trinitrate reductase activity
IC768_20285	COG1309	transcriptional regulator
IC768_20290	COG2130	NADP-dependent
IC768_20305	COG0582	viral genome integration into host DNA
IC768_20350	COG0210	DNA helicase
IC768_20370	COG0210	DNA helicase
IC768_20525	COG1525	nuclease
IC768_20695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC768_20910	COG3853	Toxic anion resistance protein (TelA)