locus-tag	class	description
IC769_00010	COG0592	DNA-directed DNA polymerase activity
IC769_00020	COG0187	DNA topoisomerase II activity
IC769_00030	COG0586	Pfam SNARE associated Golgi protein
IC769_00035	COG0488	(ABC) transporter
IC769_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC769_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC769_00105	COG0625	glutathione transferase activity
IC769_00120	COG0733	neurotransmitter:sodium symporter activity
IC769_00160	COG2233	PERMEase
IC769_00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC769_00210	COG2814	Major facilitator Superfamily
IC769_00215	COG0656	L-ascorbic acid biosynthetic process
IC769_00220	COG0583	DNA-binding transcription factor activity
IC769_00240	COG1064	alcohol dehydrogenase
IC769_00260	COG1194	a g-specific adenine glycosylase
IC769_00275	COG5487	UPF0391 membrane protein
IC769_00280	COG2983	Belongs to the UPF0260 family
IC769_00285	COG2133	pyrroloquinoline quinone binding
IC769_00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC769_00295	COG2116	formate transmembrane transporter activity
IC769_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC769_00320	COG1335	isochorismatase
IC769_00325	COG0385	Bile acid
IC769_00330	COG0534	Mate efflux family protein
IC769_00335	COG1683	Conserved Protein
IC769_00355	COG0625	glutathione transferase activity
IC769_00375	COG0523	cobalamin synthesis protein
IC769_00385	COG2188	Transcriptional regulator
IC769_00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC769_00465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC769_00475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC769_00480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC769_00580	COG0534	Mate efflux family protein
IC769_00590	COG2733	membrane
IC769_00605	COG2918	glutathione biosynthetic process
IC769_00670	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC769_00680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC769_00690	COG2233	PERMEase
IC769_00695	COG2351	hydroxyisourate hydrolase activity
IC769_00730	COG3706	GGDEF domain
IC769_00745	COG1393	Belongs to the ArsC family
IC769_00750	COG0708	Exodeoxyribonuclease III
IC769_00760	COG2983	Belongs to the UPF0260 family
IC769_00770	COG2264	protein methyltransferase activity
IC769_00795	COG0189	ligase activity
IC769_00815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC769_00825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC769_00840	COG4942	peptidase
IC769_00850	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC769_00860	COG2119	membrane
IC769_00865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC769_00865	COG0426	domain, Protein
IC769_00890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC769_00910	COG1902	pentaerythritol trinitrate reductase activity
IC769_00915	COG1519	Transferase
IC769_00920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC769_00925	COG0668	transmembrane transport
IC769_00935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC769_00940	COG1335	isochorismatase
IC769_00945	COG1522	sequence-specific DNA binding
IC769_00975	COG3162	membrane
IC769_00980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC769_00990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC769_01010	COG1309	transcriptional regulator
IC769_01030	COG4221	oxidoreductase activity
IC769_01040	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC769_01040	COG0352	thiamine-phosphate diphosphorylase activity
IC769_01040	COG0351	phosphomethylpyrimidine kinase
IC769_01050	COG2814	Major facilitator Superfamily
IC769_01065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC769_01085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC769_01090	COG1012	belongs to the aldehyde dehydrogenase family
IC769_01100	COG1335	isochorismatase
IC769_01135	COG2814	Major facilitator Superfamily
IC769_01140	COG0583	DNA-binding transcription factor activity
IC769_01180	COG1733	regulation of RNA biosynthetic process
IC769_01200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IC769_01205	COG2207	Transcriptional regulator
IC769_01210	COG3177	Filamentation induced by cAMP protein fic
IC769_01310	COG0582	viral genome integration into host DNA
IC769_01365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC769_01410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC769_01440	COG0427	acetyl-CoA hydrolase
IC769_01470	COG0659	secondary active sulfate transmembrane transporter activity
IC769_01485	COG4221	oxidoreductase activity
IC769_01495	COG0028	Belongs to the TPP enzyme family
IC769_01620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC769_01625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC769_01690	COG0070	glutamate synthase
IC769_01690	COG0069	glutamate synthase activity
IC769_01690	COG0067	glutamate synthase
IC769_01695	COG0493	'glutamate synthase
IC769_01705	COG1704	LemA family
IC769_01710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC769_01730	COG3307	-O-antigen
IC769_01750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC769_01765	COG0194	GDP metabolic process
IC769_01805	COG4969	Belongs to the N-Me-Phe pilin family
IC769_01820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC769_01830	COG0335	large ribosomal subunit rRNA binding
IC769_01840	COG5380	lipid catabolic process
IC769_01845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC769_01865	COG5006	permease, DMT superfamily
IC769_01870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC769_01875	COG0277	FAD linked oxidase domain protein
IC769_01885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC769_01890	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC769_01905	COG1289	transmembrane transporter activity
IC769_01915	COG0628	permease
IC769_01920	COG1192	Involved in chromosome partitioning
IC769_01950	COG0833	amino acid
IC769_01955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC769_01960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC769_01970	COG1012	belongs to the aldehyde dehydrogenase family
IC769_02010	COG0583	DNA-binding transcription factor activity
IC769_02015	COG1794	racemase activity, acting on amino acids and derivatives
IC769_02020	COG0583	DNA-binding transcription factor activity
IC769_02055	COG0752	glycyl-tRNA synthetase alpha subunit
IC769_02075	COG0517	IMP dehydrogenase activity
IC769_02080	COG1983	PspC domain protein
IC769_02090	COG1960	acyl-CoA dehydrogenase activity
IC769_02105	COG0408	coproporphyrinogen oxidase activity
IC769_02125	COG0513	Belongs to the DEAD box helicase family
IC769_02130	COG1127	ABC transporter
IC769_02135	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC769_02145	COG2854	intermembrane phospholipid transfer
IC769_02155	COG0598	Magnesium transport protein CorA
IC769_02170	COG1040	competence protein
IC769_02175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC769_02190	COG2937	Belongs to the GPAT DAPAT family
IC769_02195	COG1946	Acyl-CoA thioesterase
IC769_02200	COG1301	dicarboxylic acid transport
IC769_02215	COG1959	2 iron, 2 sulfur cluster binding
IC769_02220	COG1017	nitric oxide dioxygenase activity
IC769_02220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC769_02225	COG0433	COG0433 Predicted ATPase
IC769_02230	COG0626	cystathionine gamma-synthase activity
IC769_02245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC769_02250	COG0088	Forms part of the polypeptide exit tunnel
IC769_02385	COG1960	acyl-CoA dehydrogenase activity
IC769_02390	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC769_02420	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC769_02425	COG0339	signal peptide processing
IC769_02430	COG0557	exoribonuclease II activity
IC769_02475	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC769_02480	COG2169	Transcriptional regulator
IC769_02490	COG1295	ribonuclease BN
IC769_02525	COG1702	phosphate starvation-inducible protein PhoH
IC769_02535	COG0739	heme binding
IC769_02535	COG1196	nuclear chromosome segregation
IC769_02535	COG0741	lytic transglycosylase activity
IC769_02565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC769_02570	COG1183	phosphatidylcholine synthase activity
IC769_02620	COG1960	acyl-CoA dehydrogenase activity
IC769_02625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC769_02630	COG1309	transcriptional regulator
IC769_02645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC769_02650	COG1960	acyl-CoA dehydrogenase activity
IC769_02695	COG2969	positive regulation of protein catabolic process
IC769_02705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC769_02710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC769_02715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC769_02720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC769_02725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC769_02745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC769_02755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC769_02760	COG1408	metallophosphoesterase
IC769_02770	COG2199	diguanylate cyclase activity
IC769_02830	COG1607	acyl-coa hydrolase
IC769_02875	COG0613	PHP domain protein
IC769_02880	COG3781	membrane
IC769_02890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC769_02895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC769_02905	COG1862	Preprotein translocase
IC769_02940	COG3328	transposase activity
IC769_02945	COG5002	protein histidine kinase activity
IC769_02945	COG0784	Response regulator, receiver
IC769_02945	COG2205	protein histidine kinase activity
IC769_02950	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC769_02965	COG2194	sulfuric ester hydrolase activity
IC769_02975	COG0726	polysaccharide deacetylase
IC769_02980	COG0463	Glycosyl transferase, family 2
IC769_02985	COG0438	transferase activity, transferring glycosyl groups
IC769_03025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC769_03060	COG1960	acyl-CoA dehydrogenase activity
IC769_03065	COG1960	acyl-CoA dehydrogenase activity
IC769_03075	COG2205	protein histidine kinase activity
IC769_03080	COG0745	RESPONSE REGULATOR receiver
IC769_03090	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC769_03110	COG2096	Adenosyltransferase
IC769_03115	COG4206	TonB-dependent receptor
IC769_03165	COG0285	dihydrofolate synthase activity
IC769_03185	COG0450	alkyl hydroperoxide reductase
IC769_03200	COG0477	Major facilitator Superfamily
IC769_03205	COG1272	protein, Hemolysin III
IC769_03215	COG2153	protein acetylation
IC769_03235	COG0183	Belongs to the thiolase family
IC769_03240	COG2207	Transcriptional regulator
IC769_03260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC769_03275	COG0183	Belongs to the thiolase family
IC769_03285	COG2885	chlorophyll binding
IC769_03285	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC769_03295	COG1690	Belongs to the RtcB family
IC769_03300	COG0833	amino acid
IC769_03310	COG2233	PERMEase
IC769_03315	COG1217	gtp-binding protein TYPA
IC769_03345	COG2094	Belongs to the DNA glycosylase MPG family
IC769_03355	COG1902	pentaerythritol trinitrate reductase activity
IC769_03360	COG0679	Auxin Efflux Carrier
IC769_03370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC769_03375	COG0354	folic acid binding
IC769_03390	COG2233	PERMEase
IC769_03395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC769_03400	COG0251	oxidation-reduction process
IC769_03405	COG1335	isochorismatase
IC769_03410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC769_03420	COG0596	Alpha beta hydrolase
IC769_03425	COG3189	MarR family transcriptional regulator
IC769_03430	COG2824	Alkylphosphonate utilization operon protein PhnA
IC769_03435	COG3422	double-strand break repair
IC769_03475	COG0840	transmembrane signaling receptor activity
IC769_03515	COG2832	Protein of unknown function (DUF454)
IC769_03520	COG1376	ErfK ybiS ycfS ynhG family protein
IC769_03560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IC769_03570	COG1289	transmembrane transporter activity
IC769_03575	COG2814	Major facilitator Superfamily
IC769_03595	COG1115	amino acid carrier protein
IC769_03605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC769_03610	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC769_03640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC769_03650	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC769_03655	COG1077	Cell shape determining protein MreB Mrl
IC769_03660	COG1792	Involved in formation and maintenance of cell shape
IC769_03665	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC769_03670	COG0424	maF-like protein
IC769_03675	COG1530	ribonuclease E activity
IC769_03685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC769_03705	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC769_03730	COG2207	Transcriptional regulator
IC769_03795	COG0305	Participates in initiation and elongation during chromosome replication
IC769_03825	COG0582	viral genome integration into host DNA
IC769_03845	COG3046	protein related to deoxyribodipyrimidine photolyase
IC769_03850	COG2816	NAD+ diphosphatase activity
IC769_03855	COG1113	amino acid transport
IC769_03865	COG0142	geranyltranstransferase activity
IC769_03870	COG2315	Protein conserved in bacteria
IC769_03885	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC769_03905	COG2194	sulfuric ester hydrolase activity
IC769_03910	COG0745	RESPONSE REGULATOR receiver
IC769_03915	COG0642	Histidine kinase
IC769_03925	COG0004	ammonium transporteR
IC769_03930	COG0583	DNA-binding transcription factor activity
IC769_03950	COG0525	valine-tRNA ligase activity
IC769_03960	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_03970	COG0393	Putative heavy-metal-binding
IC769_03975	COG0393	Putative heavy-metal-binding
IC769_03980	COG1538	Outer membrane efflux protein
IC769_03990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC769_03995	COG0671	phosphoesterase, PA-phosphatase related
IC769_04025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC769_04045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC769_04060	COG0531	amino acid
IC769_04075	COG0321	lipoyl(octanoyl) transferase activity
IC769_04080	COG2921	Belongs to the UPF0250 family
IC769_04115	COG2009	succinate dehydrogenase
IC769_04120	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC769_04125	COG1053	succinate dehydrogenase
IC769_04130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC769_04155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC769_04175	COG2354	Protein conserved in bacteria
IC769_04180	COG2321	neutral zinc metallopeptidase
IC769_04220	COG0589	response to stress
IC769_04240	COG0505	Belongs to the CarA family
IC769_04265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC769_04320	COG0477	Major facilitator Superfamily
IC769_04325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC769_04340	COG1597	lipid kinase activity
IC769_04370	COG0584	glycerophosphoryl diester phosphodiesterase
IC769_04390	COG0741	lytic transglycosylase activity
IC769_04420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC769_04425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC769_04480	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IC769_04545	COG0582	viral genome integration into host DNA
IC769_04555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC769_04560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC769_04600	COG3811	Belongs to the UPF0386 family
IC769_04605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC769_04610	COG0778	Nitroreductase
IC769_04635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC769_04640	COG3339	Conserved Protein
IC769_04665	COG1115	amino acid carrier protein
IC769_04670	COG1113	amino acid transport
IC769_04680	COG0019	diaminopimelate decarboxylase activity
IC769_04690	COG1280	lysine exporter protein (LysE YggA)
IC769_04695	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC769_04715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC769_04735	COG0463	Glycosyl transferase, family 2
IC769_04755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC769_04790	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC769_04795	COG1136	(ABC) transporter
IC769_04810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC769_04810	COG0616	signal peptide processing
IC769_04815	COG0596	Alpha beta hydrolase
IC769_04820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC769_04830	COG0628	permease
IC769_04865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC769_04885	COG0823	Involved in the tonB-independent uptake of proteins
IC769_04905	COG0824	Thioesterase
IC769_04910	COG1473	amidohydrolase
IC769_04935	COG0047	phosphoribosylformylglycinamidine synthase activity
IC769_04935	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC769_04960	COG1024	Enoyl-CoA hydratase
IC769_04965	COG1056	cytidyltransferase-related domain
IC769_04965	COG1051	belongs to the nudix hydrolase family
IC769_04980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC769_04995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC769_05000	COG0602	queuosine metabolic process
IC769_05010	COG4625	pathogenesis
IC769_05015	COG0583	DNA-binding transcription factor activity
IC769_05020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC769_05025	COG4208	sulfate ABC transporter
IC769_05030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC769_05040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC769_05050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC769_05085	COG0681	Belongs to the peptidase S26 family
IC769_05100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC769_05110	COG1381	Involved in DNA repair and RecF pathway recombination
IC769_05115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC769_05125	COG4221	oxidoreductase activity
IC769_05170	COG3706	GGDEF domain
IC769_05175	COG0556	nucleotide-excision repair
IC769_05230	COG2070	2-Nitropropane dioxygenase
IC769_05260	COG1215	transferase activity, transferring glycosyl groups
IC769_05285	COG1252	NADH dehydrogenase
IC769_05290	COG1686	Belongs to the peptidase S11 family
IC769_05305	COG1187	pseudouridine synthase activity
IC769_05330	COG0477	Major facilitator Superfamily
IC769_05335	COG0583	DNA-binding transcription factor activity
IC769_05340	COG1823	symporter activity
IC769_05350	COG0612	Peptidase, M16
IC769_05375	COG0352	thiamine-phosphate diphosphorylase activity
IC769_05410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC769_05435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC769_05440	COG0076	glutamate decarboxylase activity
IC769_05450	COG1522	sequence-specific DNA binding
IC769_05455	COG3961	Belongs to the TPP enzyme family
IC769_05460	COG1113	amino acid transport
IC769_05465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC769_05470	COG0573	inorganic phosphate transmembrane transporter activity
IC769_05480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC769_05500	COG3647	Membrane
IC769_05525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC769_05530	COG1686	Belongs to the peptidase S11 family
IC769_05560	COG1067	ATP-dependent peptidase activity
IC769_05585	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC769_05600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC769_05605	COG1966	Carbon starvation protein
IC769_05610	COG2879	small protein
IC769_05620	COG0582	viral genome integration into host DNA
IC769_05660	COG1741	Belongs to the pirin family
IC769_05675	COG3739	integral membrane protein
IC769_05705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC769_05715	COG2840	Smr protein MutS2
IC769_05730	COG0512	Glutamine amidotransferase of anthranilate synthase
IC769_05745	COG0174	glutamine synthetase
IC769_05755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC769_05790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC769_05795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC769_05800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC769_05820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC769_05825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC769_05830	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC769_05845	COG1960	acyl-CoA dehydrogenase activity
IC769_05850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC769_05855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC769_05865	COG2223	nitrite transmembrane transporter activity
IC769_05875	COG0024	Methionine aminopeptidase
IC769_05880	COG0052	Belongs to the universal ribosomal protein uS2 family
IC769_05895	COG2207	Transcriptional regulator
IC769_05925	COG0772	Belongs to the SEDS family
IC769_05940	COG0842	Transport permease protein
IC769_05985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC769_06000	COG4215	(ABC) transporter
IC769_06005	COG4160	amino acid transport
IC769_06010	COG4598	ABC transporter
IC769_06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC769_06025	COG0826	peptidase U32
IC769_06030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC769_06045	COG1720	tRNA m6t6A37 methyltransferase activity
IC769_06055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC769_06070	COG0642	Histidine kinase
IC769_06080	COG0494	nUDIX hydrolase
IC769_06090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC769_06095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC769_06100	COG3139	Protein of unknown function (DUF1315)
IC769_06105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC769_06110	COG1301	dicarboxylic acid transport
IC769_06115	COG1960	acyl-CoA dehydrogenase activity
IC769_06135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC769_06145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC769_06150	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC769_06170	COG1690	Belongs to the RtcB family
IC769_06175	COG1234	tRNA 3'-trailer cleavage
IC769_06180	COG4650	regulator
IC769_06210	COG2363	Small membrane protein
IC769_06230	COG0513	Belongs to the DEAD box helicase family
IC769_06240	COG0778	Nitroreductase
IC769_06300	COG1610	YqeY-like protein
IC769_06330	COG2815	serine threonine protein kinase
IC769_06330	COG0515	serine threonine protein kinase
IC769_06355	COG2831	hemolysin activation secretion protein
IC769_06415	COG0786	glutamate:sodium symporter activity
IC769_06420	COG0475	glutathione-regulated potassium exporter activity
IC769_06420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC769_06425	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_06505	COG1309	transcriptional regulator
IC769_06530	COG2985	domain, Protein
IC769_06555	COG2995	paraquat-inducible protein a
IC769_06560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC769_06560	COG3008	intermembrane lipid transfer
IC769_06570	COG2351	hydroxyisourate hydrolase activity
IC769_06585	COG5002	protein histidine kinase activity
IC769_06610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC769_06620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC769_06625	COG0642	Histidine kinase
IC769_06630	COG0745	RESPONSE REGULATOR receiver
IC769_06655	COG2175	clavaminate synthase activity
IC769_06665	COG2814	Major facilitator Superfamily
IC769_06680	COG2855	membrane
IC769_06725	COG1301	dicarboxylic acid transport
IC769_06740	COG2011	ABC-type metal ion transport system permease component
IC769_06745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC769_06750	COG1464	Belongs to the NlpA lipoprotein family
IC769_06755	COG0151	Belongs to the GarS family
IC769_06760	COG0138	bifunctional purine biosynthesis protein purh
IC769_06765	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC769_06795	COG2308	Evidence 4 Homologs of previously reported genes of
IC769_06805	COG1305	Transglutaminase-like
IC769_06815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC769_06845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC769_06855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC769_06890	COG1215	transferase activity, transferring glycosyl groups
IC769_06895	COG3658	cytochrome
IC769_06925	COG2890	protein-(glutamine-N5) methyltransferase activity
IC769_06930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC769_06935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC769_06950	COG1960	acyl-CoA dehydrogenase activity
IC769_06960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC769_06985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC769_06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC769_06995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC769_07000	COG2205	protein histidine kinase activity
IC769_07005	COG0745	RESPONSE REGULATOR receiver
IC769_07010	COG0174	glutamine synthetase
IC769_07030	COG0729	surface antigen
IC769_07060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC769_07065	COG2814	Major facilitator Superfamily
IC769_07075	COG0583	DNA-binding transcription factor activity
IC769_07090	COG1187	pseudouridine synthase activity
IC769_07110	COG0802	atpase or kinase
IC769_07125	COG1923	regulation of RNA biosynthetic process
IC769_07130	COG0697	spore germination
IC769_07155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC769_07160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC769_07160	COG0519	Catalyzes the synthesis of GMP from XMP
IC769_07165	COG4302	ethanolamine ammonia-lyase activity
IC769_07170	COG4303	Ethanolamine ammonia lyase large subunit
IC769_07175	COG0531	amino acid
IC769_07200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC769_07210	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC769_07230	COG0308	aminopeptidase N
IC769_07260	COG0625	glutathione transferase activity
IC769_07275	COG1605	Chorismate mutase
IC769_07305	COG4264	IucA IucC family
IC769_07315	COG4264	IucA IucC family
IC769_07320	COG2423	ornithine cyclodeaminase activity
IC769_07335	COG0668	transmembrane transport
IC769_07375	COG0488	(ABC) transporter
IC769_07380	COG0589	response to stress
IC769_07405	COG3135	benzoate transporter
IC769_07410	COG1522	sequence-specific DNA binding
IC769_07420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC769_07425	COG0583	DNA-binding transcription factor activity
IC769_07435	COG0183	Belongs to the thiolase family
IC769_07440	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_07445	COG2030	dehydratase
IC769_07450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC769_07475	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC769_07485	COG3328	transposase activity
IC769_07495	COG0824	Thioesterase
IC769_07500	COG1454	alcohol dehydrogenase
IC769_07515	COG1335	isochorismatase
IC769_07530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC769_07565	COG2814	Major facilitator Superfamily
IC769_07580	COG0511	ligase activity, forming carbon-carbon bonds
IC769_07600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC769_07600	COG1116	anion transmembrane transporter activity
IC769_07605	COG0745	RESPONSE REGULATOR receiver
IC769_07615	COG2146	nitrite reductase [NAD(P)H] activity
IC769_07615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC769_07620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC769_07625	COG0243	molybdopterin cofactor binding
IC769_07635	COG0243	molybdopterin cofactor binding
IC769_07640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC769_07655	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC769_07655	COG0315	cyclic pyranopterin monophosphate synthase activity
IC769_07660	COG0303	'Molybdopterin
IC769_07670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC769_07695	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC769_07700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC769_07755	COG2204	response regulator
IC769_07760	COG3852	Histidine kinase
IC769_07785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC769_07790	COG0575	Belongs to the CDS family
IC769_07825	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC769_07840	COG2137	regulation of response to DNA damage stimulus
IC769_07855	COG1011	Hydrolase
IC769_07870	COG1522	sequence-specific DNA binding
IC769_07880	COG1113	amino acid transport
IC769_07890	COG0659	secondary active sulfate transmembrane transporter activity
IC769_07905	COG3300	MHYT domain
IC769_07905	COG5001	Diguanylate cyclase
IC769_07935	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC769_07935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC769_07935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC769_07940	COG1105	Belongs to the carbohydrate kinase PfkB family
IC769_07945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC769_07945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC769_07975	COG0024	Methionine aminopeptidase
IC769_07980	COG0583	DNA-binding transcription factor activity
IC769_07990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC769_07995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC769_08000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC769_08025	COG0552	protein localization to endoplasmic reticulum
IC769_08035	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IC769_08050	COG4890	Cyd operon protein YbgT
IC769_08055	COG1294	oxidase, subunit
IC769_08070	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC769_08080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC769_08085	COG4774	siderophore transport
IC769_08100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC769_08105	COG0569	domain protein
IC769_08110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC769_08140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC769_08145	COG0542	response to heat
IC769_08155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC769_08170	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC769_08170	COG1902	pentaerythritol trinitrate reductase activity
IC769_08210	COG0148	phosphopyruvate hydratase activity
IC769_08215	COG2323	membrane
IC769_08225	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC769_08235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC769_08240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC769_08245	COG0183	Belongs to the thiolase family
IC769_08250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC769_08255	COG0596	Alpha beta hydrolase
IC769_08260	COG2271	Major facilitator Superfamily
IC769_08265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC769_08270	COG3485	protocatechuate 3,4-dioxygenase
IC769_08275	COG3485	protocatechuate 3,4-dioxygenase
IC769_08280	COG0710	3-dehydroquinate dehydratase activity
IC769_08290	COG3659	wide pore channel activity
IC769_08305	COG2391	methyltransferase activity
IC769_08320	COG1414	Transcriptional regulator
IC769_08325	COG0583	DNA-binding transcription factor activity
IC769_08355	COG2814	Major facilitator Superfamily
IC769_08365	COG0154	amidase activity
IC769_08395	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_08405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC769_08415	COG3733	amine oxidase
IC769_08430	COG1012	belongs to the aldehyde dehydrogenase family
IC769_08435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC769_08440	COG0183	Belongs to the thiolase family
IC769_08445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC769_08450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC769_08460	COG4829	muconolactone delta-isomerase
IC769_08465	COG4948	Mandelate Racemase Muconate Lactonizing
IC769_08470	COG0583	DNA-binding transcription factor activity
IC769_08500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC769_08525	COG1309	transcriptional regulator
IC769_08535	COG4774	siderophore transport
IC769_08605	COG2188	Transcriptional regulator
IC769_08620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC769_08645	COG1566	PFAM secretion protein HlyD family protein
IC769_08680	COG1120	ATPase activity
IC769_08800	COG2431	L-lysine efflux transmembrane transporter activity
IC769_08810	COG3328	transposase activity
IC769_08825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC769_08835	COG0745	RESPONSE REGULATOR receiver
IC769_08855	COG2072	flavoprotein involved in K transport
IC769_08870	COG1012	belongs to the aldehyde dehydrogenase family
IC769_08905	COG2175	clavaminate synthase activity
IC769_08910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC769_08925	COG0667	Aldo Keto reductase
IC769_08930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC769_08945	COG2175	clavaminate synthase activity
IC769_08975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC769_08980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC769_09015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC769_09020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC769_09025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC769_09050	COG0805	protein transport
IC769_09060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC769_09080	COG1132	(ABC) transporter
IC769_09105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC769_09110	COG0601	transmembrane transport
IC769_09140	COG3539	Fimbrial protein
IC769_09165	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC769_09175	COG0753	catalase activity
IC769_09185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC769_09190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC769_09255	COG4771	TonB-dependent receptor
IC769_09265	COG1535	isochorismatase
IC769_09265	COG3433	isochorismatase activity
IC769_09270	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC769_09275	COG1169	isochorismate synthase
IC769_09290	COG3251	PFAM MbtH domain protein
IC769_09320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC769_09325	COG4149	molybdate abc transporter
IC769_09340	COG4638	Rieske (2fe-2S)
IC769_09345	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC769_09350	COG0543	2 iron, 2 sulfur cluster binding
IC769_09350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC769_09365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC769_09375	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_09395	COG2207	Transcriptional regulator
IC769_09400	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_09405	COG2610	gluconate transmembrane transporter activity
IC769_09410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC769_09440	COG2814	Major facilitator Superfamily
IC769_09465	COG0583	DNA-binding transcription factor activity
IC769_09480	COG2031	fatty acid transporter
IC769_09485	COG0183	Belongs to the thiolase family
IC769_09490	COG0583	DNA-binding transcription factor activity
IC769_09495	COG0583	DNA-binding transcription factor activity
IC769_09510	COG1027	Aspartate ammonia-lyase
IC769_09520	COG0477	Major facilitator Superfamily
IC769_09530	COG2207	Transcriptional regulator
IC769_09530	COG3708	Transcriptional regulator
IC769_09545	COG0730	response to heat
IC769_09555	COG3453	Protein conserved in bacteria
IC769_09555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC769_09565	COG3781	membrane
IC769_09570	COG1063	alcohol dehydrogenase
IC769_09585	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC769_09590	COG0022	dehydrogenase e1 component
IC769_09595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC769_09600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC769_09615	COG3706	GGDEF domain
IC769_09630	COG0133	tryptophan synthase activity
IC769_09640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC769_09675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC769_09700	COG2226	methyltransferase
IC769_09755	COG0842	Transport permease protein
IC769_09760	COG0842	Transport permease protein
IC769_09765	COG1131	(ABC) transporter
IC769_09780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC769_09805	COG0730	response to heat
IC769_09810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC769_09825	COG0406	alpha-ribazole phosphatase activity
IC769_09830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC769_09850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC769_09865	COG1960	acyl-CoA dehydrogenase activity
IC769_09875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC769_09880	COG2207	Transcriptional regulator
IC769_09885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC769_09890	COG0776	regulation of translation
IC769_09915	COG0822	iron-sulfur transferase activity
IC769_09920	COG0316	Belongs to the HesB IscA family
IC769_09970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC769_09975	COG0702	epimerase
IC769_10010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC769_10015	COG0601	transmembrane transport
IC769_10045	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC769_10070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC769_10075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC769_10105	COG0776	regulation of translation
IC769_10170	COG0084	hydrolase, TatD family'
IC769_10190	COG1663	tetraacyldisaccharide 4'-kinase activity
IC769_10195	COG1132	(ABC) transporter
IC769_10205	COG0811	peptide transport
IC769_10210	COG1475	DNA binding
IC769_10215	COG1192	Involved in chromosome partitioning
IC769_10225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC769_10265	COG0424	maF-like protein
IC769_10270	COG2850	peptidyl-arginine hydroxylation
IC769_10280	COG0640	Transcriptional regulator
IC769_10290	COG3619	membrane
IC769_10295	COG3122	Protein conserved in bacteria
IC769_10300	COG1132	(ABC) transporter
IC769_10320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC769_10325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC769_10335	COG0506	proline dehydrogenase activity
IC769_10335	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC769_10335	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC769_10340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC769_10355	COG3698	Phosphodiester glycosidase
IC769_10380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC769_10405	COG2353	YceI-like domain
IC769_10420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC769_10460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC769_10460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC769_10485	COG3539	Fimbrial protein
IC769_10490	COG3121	Chaperone
IC769_10510	COG0697	spore germination
IC769_10520	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC769_10530	COG0583	DNA-binding transcription factor activity
IC769_10550	COG2197	response regulator
IC769_10580	COG1522	sequence-specific DNA binding
IC769_10590	COG1126	abc transporter atp-binding protein
IC769_10595	COG0765	amino acid transport
IC769_10600	COG0765	amino acid transport
IC769_10630	COG1464	Belongs to the NlpA lipoprotein family
IC769_10635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC769_10640	COG2011	ABC-type metal ion transport system permease component
IC769_10645	COG0012	GTP binding
IC769_10670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC769_10710	COG0386	Belongs to the glutathione peroxidase family
IC769_10720	COG0436	Aminotransferase
IC769_10725	COG1301	dicarboxylic acid transport
IC769_10760	COG3634	alkyl hydroperoxide reductase activity
IC769_10775	COG0583	DNA-binding transcription factor activity
IC769_10780	COG0431	NADPH-dependent FMN reductase
IC769_10785	COG0798	PFAM Bile acid sodium symporter
IC769_10790	COG0640	Transcriptional regulator
IC769_10805	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IC769_10815	COG0583	DNA-binding transcription factor activity
IC769_10825	COG1953	Uracil, thiamine, allantoin
IC769_10840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC769_10845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC769_10850	COG4521	taurine ABC transporter
IC769_10860	COG0477	Major facilitator Superfamily
IC769_10885	COG1271	oxidase subunit
IC769_10890	COG1294	oxidase, subunit
IC769_10900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC769_10920	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC769_10940	COG3052	prosthetic group binding
IC769_10945	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC769_10970	COG1346	cytolysis
IC769_10980	COG0583	DNA-binding transcription factor activity
IC769_10985	COG0625	glutathione transferase activity
IC769_10990	COG0625	glutathione transferase activity
IC769_11010	COG0583	DNA-binding transcription factor activity
IC769_11015	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_11025	COG1045	serine acetyltransferase
IC769_11030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC769_11040	COG1280	lysine exporter protein (LysE YggA)
IC769_11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC769_11060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC769_11070	COG0765	amino acid transport
IC769_11075	COG0765	amino acid transport
IC769_11115	COG2205	protein histidine kinase activity
IC769_11115	COG0784	Response regulator, receiver
IC769_11155	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_11220	COG0318	PFAM AMP-dependent synthetase and ligase
IC769_11225	COG1309	transcriptional regulator
IC769_11230	COG1960	acyl-CoA dehydrogenase activity
IC769_11235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC769_11240	COG1024	Enoyl-CoA hydratase
IC769_11245	COG4770	biotin carboxylase activity
IC769_11280	COG2814	Major facilitator Superfamily
IC769_11290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC769_11295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC769_11300	COG2814	Major facilitator Superfamily
IC769_11305	COG1960	acyl-CoA dehydrogenase activity
IC769_11310	COG1024	Enoyl-CoA hydratase
IC769_11315	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_11320	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC769_11325	COG0183	Belongs to the thiolase family
IC769_11335	COG2814	Major facilitator Superfamily
IC769_11350	COG1024	Enoyl-CoA hydratase
IC769_11360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC769_11365	COG1960	acyl-CoA dehydrogenase activity
IC769_11375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC769_11400	COG1840	ABC-type Fe3 transport system, periplasmic component
IC769_11415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC769_11420	COG1414	Transcriptional regulator
IC769_11430	COG0583	DNA-binding transcription factor activity
IC769_11445	COG1733	regulation of RNA biosynthetic process
IC769_11465	COG0531	amino acid
IC769_11470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC769_11485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC769_11490	COG1309	transcriptional regulator
IC769_11500	COG2050	protein possibly involved in aromatic compounds catabolism
IC769_11510	COG3327	negative regulation of DNA-templated transcription, initiation
IC769_11515	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC769_11520	COG0183	Belongs to the thiolase family
IC769_11530	COG1024	Enoyl-CoA hydratase
IC769_11535	COG1024	Enoyl-CoA hydratase
IC769_11550	COG3396	Phenylacetate-CoA oxygenase
IC769_11555	COG3460	Phenylacetate-CoA oxygenase
IC769_11560	COG3396	Phenylacetate-CoA oxygenase
IC769_11565	COG1012	belongs to the aldehyde dehydrogenase family
IC769_11565	COG2030	dehydratase
IC769_11570	COG1760	l-serine dehydratase
IC769_11580	COG0789	Transcriptional regulator
IC769_11590	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC769_11595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC769_11610	COG2807	transmembrane transport
IC769_11670	COG1116	anion transmembrane transporter activity
IC769_11675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC769_11685	COG0864	Transcriptional regulator
IC769_11700	COG1733	regulation of RNA biosynthetic process
IC769_11705	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC769_11710	COG0439	Biotin carboxylase
IC769_11760	COG0038	chloride channel
IC769_11765	COG4770	biotin carboxylase activity
IC769_11785	COG1914	H( )-stimulated, divalent metal cation uptake system
IC769_11790	COG0583	DNA-binding transcription factor activity
IC769_11800	COG1595	DNA-templated transcription, initiation
IC769_11810	COG3220	belongs to the UPF0276 family
IC769_11825	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_11840	COG2076	Multidrug Resistance protein
IC769_11855	COG3713	MltA-interacting MipA family protein
IC769_11860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC769_11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC769_11960	COG1309	transcriptional regulator
IC769_11965	COG1278	Cold shock
IC769_11975	COG0626	cystathionine gamma-synthase activity
IC769_11985	COG1522	sequence-specific DNA binding
IC769_11995	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_12065	COG1271	oxidase subunit
IC769_12070	COG1294	oxidase, subunit
IC769_12080	COG1469	GTP cyclohydrolase I activity
IC769_12100	COG1560	Kdo2-lipid A biosynthetic process
IC769_12145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC769_12155	COG4122	O-methyltransferase activity
IC769_12185	COG1538	Outer membrane efflux protein
IC769_12190	COG1137	ATPase activity
IC769_12195	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC769_12205	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC769_12210	COG0517	IMP dehydrogenase activity
IC769_12210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC769_12230	COG0667	Aldo Keto reductase
IC769_12240	COG2814	Major facilitator Superfamily
IC769_12270	COG1278	Cold shock
IC769_12395	COG2871	sodium ion transport
IC769_12405	COG0583	DNA-binding transcription factor activity
IC769_12415	COG4638	Rieske (2fe-2S)
IC769_12420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC769_12425	COG0633	Ferredoxin
IC769_12425	COG0543	2 iron, 2 sulfur cluster binding
IC769_12430	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_12435	COG3135	benzoate transporter
IC769_12480	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC769_12490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IC769_12500	COG3634	alkyl hydroperoxide reductase activity
IC769_12520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC769_12525	COG0625	glutathione transferase activity
IC769_12585	COG1765	OsmC-like protein
IC769_12595	COG0667	Aldo Keto reductase
IC769_12610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC769_12625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC769_12645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC769_12655	COG3038	cytochrome b561
IC769_12660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC769_12665	COG2252	PERMEase
IC769_12675	COG2072	flavoprotein involved in K transport
IC769_12690	COG1741	Belongs to the pirin family
IC769_12695	COG1309	transcriptional regulator
IC769_12710	COG2072	flavoprotein involved in K transport
IC769_12715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC769_12745	COG1944	ATP diphosphatase activity
IC769_12765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC769_12780	COG2814	Major facilitator Superfamily
IC769_12790	COG1012	belongs to the aldehyde dehydrogenase family
IC769_12800	COG1960	acyl-CoA dehydrogenase activity
IC769_12820	COG0697	spore germination
IC769_12840	COG1113	amino acid transport
IC769_12860	COG1012	belongs to the aldehyde dehydrogenase family
IC769_12950	COG3209	COG3209 Rhs family protein
IC769_13060	COG0583	DNA-binding transcription factor activity
IC769_13070	COG0251	oxidation-reduction process
IC769_13090	COG1902	pentaerythritol trinitrate reductase activity
IC769_13090	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC769_13100	COG5001	Diguanylate cyclase
IC769_13100	COG4251	negative regulation of phosphorylation
IC769_13100	COG3706	GGDEF domain
IC769_13100	COG2203	Gaf domain
IC769_13135	COG4172	Belongs to the ABC transporter superfamily
IC769_13140	COG4239	(ABC) transporter, permease
IC769_13145	COG4174	ABC transporter (Permease)
IC769_13200	COG0583	DNA-binding transcription factor activity
IC769_13205	COG1279	arginine transmembrane transporter activity
IC769_13225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC769_13235	COG0006	proline dipeptidase activity
IC769_13295	COG3384	dioxygenase
IC769_13305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC769_13310	COG2878	Part of a membrane complex involved in electron transport
IC769_13315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC769_13340	COG0768	penicillin binding
IC769_13345	COG0742	ribosomal rna small subunit methyltransferase
IC769_13395	COG1253	flavin adenine dinucleotide binding
IC769_13400	COG2851	Citrate transporter
IC769_13450	COG1773	rubredoxin
IC769_13455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC769_13465	COG0583	DNA-binding transcription factor activity
IC769_13490	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC769_13495	COG4181	ATPase activity
IC769_13540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC769_13560	COG0306	phosphate transporter
IC769_13605	COG2207	Transcriptional regulator
IC769_13610	COG2066	Belongs to the glutaminase family
IC769_13615	COG0242	peptide deformylase activity
IC769_13620	COG0477	Major facilitator Superfamily
IC769_13630	COG0028	Belongs to the TPP enzyme family
IC769_13635	COG1012	belongs to the aldehyde dehydrogenase family
IC769_13645	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_13665	COG1414	Transcriptional regulator
IC769_13695	COG1024	Enoyl-CoA hydratase
IC769_13705	COG1215	transferase activity, transferring glycosyl groups
IC769_13710	COG0726	polysaccharide deacetylase
IC769_13710	COG1649	PFAM Uncharacterised BCR, COG1649
IC769_13720	COG4681	YaeQ
IC769_13730	COG0523	cobalamin synthesis protein
IC769_13740	COG1607	acyl-coa hydrolase
IC769_13750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC769_13755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC769_13760	COG1309	transcriptional regulator
IC769_13785	COG2040	homocysteine
IC769_13790	COG0531	amino acid
IC769_13845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC769_13850	COG0477	Major facilitator Superfamily
IC769_13910	COG0405	Gamma-glutamyltransferase
IC769_13915	COG2814	Major facilitator Superfamily
IC769_13925	COG2050	protein possibly involved in aromatic compounds catabolism
IC769_13940	COG1090	epimerase
IC769_13960	COG0420	3'-5' exonuclease activity
IC769_13970	COG1968	undecaprenyl-diphosphatase activity
IC769_13990	COG0735	belongs to the Fur family
IC769_13995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC769_14000	COG2914	Belongs to the UPF0125 (RnfH) family
IC769_14015	COG0121	glutamine amidotransferase
IC769_14030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC769_14040	COG0210	DNA helicase
IC769_14045	COG2885	chlorophyll binding
IC769_14050	COG0204	Acyl-transferase
IC769_14080	COG1280	lysine exporter protein (LysE YggA)
IC769_14090	COG0492	ferredoxin-NADP+ reductase activity
IC769_14095	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC769_14105	COG0456	acetyltransferase
IC769_14125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC769_14135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC769_14150	COG1981	membrane
IC769_14160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC769_14160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC769_14180	COG1012	belongs to the aldehyde dehydrogenase family
IC769_14185	COG4638	Rieske (2fe-2S)
IC769_14190	COG0657	acetylesterase activity
IC769_14205	COG0583	DNA-binding transcription factor activity
IC769_14225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC769_14250	COG0564	pseudouridine synthase activity
IC769_14260	COG0358	DNA primase activity
IC769_14275	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC769_14305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC769_14335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC769_14345	COG0351	phosphomethylpyrimidine kinase
IC769_14345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC769_14345	COG0352	thiamine-phosphate diphosphorylase activity
IC769_14350	COG1652	LysM domain
IC769_14375	COG1399	metal-binding, possibly nucleic acid-binding protein
IC769_14380	COG3101	peptidyl-lysine hydroxylation
IC769_14385	COG0009	L-threonylcarbamoyladenylate synthase
IC769_14390	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC769_14395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC769_14410	COG4106	trans-aconitate 2-methyltransferase activity
IC769_14425	COG2226	methyltransferase
IC769_14425	COG0596	Alpha beta hydrolase
IC769_14425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC769_14430	COG1877	trehalose-phosphatase activity
IC769_14435	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC769_14440	COG2223	nitrite transmembrane transporter activity
IC769_14460	COG1196	nuclear chromosome segregation
IC769_14470	COG0730	response to heat
IC769_14485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC769_14495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC769_14540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC769_14545	COG0489	protein tyrosine kinase activity
IC769_14555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC769_14555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC769_14590	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC769_14595	COG2081	HI0933 family
IC769_14605	COG0668	transmembrane transport
IC769_14625	COG0583	DNA-binding transcription factor activity
IC769_14650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC769_14655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC769_14670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC769_14685	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC769_14710	COG3706	GGDEF domain
IC769_14725	COG0745	RESPONSE REGULATOR receiver
IC769_14745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC769_14775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC769_14780	COG0583	DNA-binding transcription factor activity
IC769_14845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC769_14860	COG0583	DNA-binding transcription factor activity
IC769_14870	COG0583	DNA-binding transcription factor activity
IC769_14905	COG1309	transcriptional regulator
IC769_14915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC769_14920	COG2814	Major facilitator Superfamily
IC769_14925	COG1960	acyl-CoA dehydrogenase activity
IC769_14930	COG0583	DNA-binding transcription factor activity
IC769_14935	COG1063	alcohol dehydrogenase
IC769_15015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC769_15020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC769_15025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC769_15045	COG2132	Multicopper oxidase
IC769_15055	COG0561	phosphatase activity
IC769_15060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC769_15070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC769_15085	COG1214	PFAM Peptidase M22, glycoprotease
IC769_15145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC769_15150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC769_15155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC769_15215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC769_15225	COG1846	Transcriptional regulator
IC769_15230	COG1764	response to oxidative stress
IC769_15270	COG0037	tRNA processing
IC769_15280	COG0248	Ppx GppA phosphatase
IC769_15310	COG0072	phenylalanine-tRNA ligase activity
IC769_15340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC769_15350	COG1238	metal cluster binding
IC769_15355	COG0625	glutathione transferase activity
IC769_15370	COG0318	PFAM AMP-dependent synthetase and ligase
IC769_15375	COG3028	Belongs to the UPF0307 family
IC769_15400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC769_15405	COG0617	tRNA 3'-terminal CCA addition
IC769_15410	COG1555	photosystem II stabilization
IC769_15415	COG3956	TIGRFAM MazG family protein
IC769_15425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC769_15445	COG0784	Response regulator, receiver
IC769_15445	COG2205	protein histidine kinase activity
IC769_15445	COG5002	protein histidine kinase activity
IC769_15450	COG1024	Enoyl-CoA hydratase
IC769_15455	COG2084	Dehydrogenase
IC769_15495	COG0697	spore germination
IC769_15505	COG2814	Major facilitator Superfamily
IC769_15510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC769_15520	COG0583	DNA-binding transcription factor activity
IC769_15530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC769_15560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC769_15625	COG3328	transposase activity
IC769_15715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC769_15720	COG0440	acetolactate synthase activity
IC769_15750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC769_15755	COG1136	(ABC) transporter
IC769_15755	COG0577	efflux transmembrane transporter activity
IC769_15775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC769_15780	COG1162	GTPase activity
IC769_15790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC769_15830	COG1426	Protein conserved in bacteria
IC769_15865	COG0793	Belongs to the peptidase S41A family
IC769_15890	COG1012	belongs to the aldehyde dehydrogenase family
IC769_15895	COG3265	gluconokinase activity
IC769_15905	COG0800	Aldolase
IC769_15915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC769_15920	COG0857	belongs to the CobB CobQ family
IC769_15920	COG0280	phosphate acetyltransferase
IC769_15925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC769_15925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC769_15945	COG0740	serine-type endopeptidase activity
IC769_15955	COG4774	siderophore transport
IC769_15965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC769_15975	COG2813	Specifically methylates the guanine in position
IC769_15975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC769_16070	COG0788	formyltetrahydrofolate deformylase activity
IC769_16095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC769_16095	COG4651	solute:proton antiporter activity
IC769_16115	COG0724	RNA recognition motif
IC769_16120	COG0210	DNA helicase
IC769_16145	COG1733	regulation of RNA biosynthetic process
IC769_16155	COG2900	Belongs to the SlyX family
IC769_16160	COG0488	(ABC) transporter
IC769_16170	COG1280	lysine exporter protein (LysE YggA)
IC769_16175	COG1560	Kdo2-lipid A biosynthetic process
IC769_16185	COG1301	dicarboxylic acid transport
IC769_16240	COG0473	3-isopropylmalate dehydrogenase activity
IC769_16265	COG0583	DNA-binding transcription factor activity
IC769_16310	COG0583	DNA-binding transcription factor activity
IC769_16320	COG0625	glutathione transferase activity
IC769_16325	COG2378	regulation of single-species biofilm formation
IC769_16340	COG1530	ribonuclease E activity
IC769_16345	COG0318	PFAM AMP-dependent synthetase and ligase
IC769_16360	COG0583	DNA-binding transcription factor activity
IC769_16365	COG4221	oxidoreductase activity
IC769_16370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC769_16380	COG0534	Mate efflux family protein
IC769_16395	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC769_16425	COG0493	'glutamate synthase
IC769_16425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC769_16435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC769_16440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC769_16455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC769_16465	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC769_16465	COG0644	oxidoreductase
IC769_16480	COG4535	Mg2 and Co2 transporter CorC
IC769_16490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC769_16515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC769_16520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC769_16520	COG0475	glutathione-regulated potassium exporter activity
IC769_16525	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC769_16530	COG1280	lysine exporter protein (LysE YggA)
IC769_16540	COG0789	Transcriptional regulator
IC769_16545	COG0598	Magnesium transport protein CorA
IC769_16550	COG1185	polyribonucleotide nucleotidyltransferase activity
IC769_16570	COG1074	ATP-dependent DNA helicase activity
IC769_16575	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC769_16600	COG2226	methyltransferase
IC769_16615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC769_16630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC769_16645	COG2111	Na H antiporter
IC769_16645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC769_16650	COG1006	Multisubunit Na H antiporter MnhC subunit
IC769_16655	COG0651	ATP synthesis coupled electron transport
IC769_16660	COG1863	multisubunit Na H antiporter MnhE subunit
IC769_16665	COG2212	antiporter activity
IC769_16670	COG1320	monovalent cation:proton antiporter activity
IC769_16675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC769_16685	COG0195	Participates in both transcription termination and antitermination
IC769_16735	COG0237	dephospho-CoA kinase activity
IC769_16745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC769_16755	COG0497	DNA recombination
IC769_16765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC769_16780	COG1289	transmembrane transporter activity
IC769_16795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC769_16855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC769_16870	COG0326	Molecular chaperone. Has ATPase activity
IC769_16885	COG2056	Na+-H+ antiporter family
IC769_16890	COG0596	Alpha beta hydrolase
IC769_16920	COG0222	ribosome binding
IC769_16985	COG0546	phosphoglycolate phosphatase activity
IC769_16990	COG1716	ATPase activity
IC769_17035	COG0181	hydroxymethylbilane synthase activity
IC769_17045	COG3275	phosphorelay sensor kinase activity
IC769_17065	COG1538	Outer membrane efflux protein
IC769_17070	COG0697	spore germination
IC769_17090	COG0494	nUDIX hydrolase
IC769_17100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC769_17105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC769_17110	COG0772	Belongs to the SEDS family
IC769_17135	COG4974	Belongs to the 'phage' integrase family
IC769_17140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC769_17150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC769_17160	COG2197	response regulator
IC769_17180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC769_17185	COG0795	lipopolysaccharide-transporting ATPase activity
IC769_17190	COG0795	lipopolysaccharide-transporting ATPase activity
IC769_17225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC769_17225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC769_17235	COG0004	ammonium transporteR
IC769_17240	COG0347	Belongs to the P(II) protein family
IC769_17250	COG0606	chelatase, subunit chli
IC769_17260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC769_17265	COG0235	Class ii aldolase
IC769_17270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC769_17285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC769_17310	COG0477	Major facilitator Superfamily
IC769_17315	COG2860	membrane
IC769_17320	COG3012	SEC-C Motif Domain Protein
IC769_17325	COG1253	flavin adenine dinucleotide binding
IC769_17335	COG2814	Major facilitator Superfamily
IC769_17345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC769_17380	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC769_17395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC769_17430	COG1309	transcriptional regulator
IC769_17465	COG0758	DNA mediated transformation
IC769_17475	COG0697	spore germination
IC769_17480	COG1309	transcriptional regulator
IC769_17495	COG0386	Belongs to the glutathione peroxidase family
IC769_17505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC769_17510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC769_17560	COG1121	(ABC) transporter
IC769_17570	COG1280	lysine exporter protein (LysE YggA)
IC769_17575	COG2837	iron assimilation
IC769_17585	COG0281	malic enzyme
IC769_17620	COG0735	belongs to the Fur family
IC769_17630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC769_17635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC769_17635	COG0519	Catalyzes the synthesis of GMP from XMP
IC769_17640	COG4399	Belongs to the UPF0754 family
IC769_17645	COG2259	Doxx family
IC769_17650	COG0586	Pfam SNARE associated Golgi protein
IC769_17665	COG1192	Involved in chromosome partitioning
IC769_17675	COG0271	Belongs to the BolA IbaG family
IC769_17715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC769_17715	COG0300	oxidoreductase activity
IC769_17715	COG3321	synthase
IC769_17715	COG4221	oxidoreductase activity
IC769_17720	COG1960	acyl-CoA dehydrogenase activity
IC769_17730	COG2197	response regulator
IC769_17740	COG3916	Acyl-homoserine-lactone synthase
IC769_17745	COG0477	Major facilitator Superfamily
IC769_17750	COG1024	Enoyl-CoA hydratase
IC769_17755	COG1024	Enoyl-CoA hydratase
IC769_17760	COG1960	acyl-CoA dehydrogenase activity
IC769_17785	COG1113	amino acid transport
IC769_17790	COG1113	amino acid transport
IC769_17795	COG0251	oxidation-reduction process
IC769_17835	COG0564	pseudouridine synthase activity
IC769_17910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC769_17925	COG1802	Transcriptional regulator
IC769_17930	COG1448	Aminotransferase
IC769_17935	COG0277	FAD linked oxidase domain protein
IC769_17945	COG2186	Transcriptional regulator
IC769_17955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC769_17965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC769_17980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC769_18055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC769_18060	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC769_18070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC769_18075	COG1596	polysaccharide export
IC769_18100	COG0728	peptidoglycan biosynthetic process
IC769_18105	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC769_18160	COG0546	phosphoglycolate phosphatase activity
IC769_18165	COG1028	Short-chain dehydrogenase reductase Sdr
IC769_18180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC769_18180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC769_18185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC769_18190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC769_18195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC769_18200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC769_18205	COG1116	anion transmembrane transporter activity
IC769_18210	COG1309	transcriptional regulator
IC769_18215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC769_18225	COG0196	riboflavin kinase activity
IC769_18240	COG1047	Peptidyl-prolyl cis-trans
IC769_18280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC769_18285	COG0657	acetylesterase activity
IC769_18335	COG2951	lytic endotransglycosylase activity
IC769_18340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC769_18355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC769_18365	COG0671	phosphoesterase, PA-phosphatase related
IC769_18370	COG0861	Integral membrane protein TerC family
IC769_18380	COG0402	S-adenosylhomocysteine deaminase activity
IC769_18395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC769_18440	COG3328	transposase activity
IC769_18480	COG1192	Involved in chromosome partitioning
IC769_18485	COG1475	DNA binding
IC769_18675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC769_18685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IC769_18720	COG0625	glutathione transferase activity
IC769_18725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IC769_18745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC769_18780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC769_18855	COG2826	transposase and inactivated derivatives, IS30 family
IC769_18865	COG2826	transposase and inactivated derivatives, IS30 family
IC769_18960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC769_19015	COG1525	nuclease
IC769_19065	COG3421	Type III restriction
IC769_19110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC769_19210	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC769_19240	COG0745	RESPONSE REGULATOR receiver
IC769_19245	COG5002	protein histidine kinase activity
IC769_19255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC769_19275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC769_19340	COG3657	addiction module killer protein
IC769_19345	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC769_19365	COG0488	(ABC) transporter
IC769_19370	COG3173	Aminoglycoside phosphotransferase
IC769_19380	COG0583	DNA-binding transcription factor activity
IC769_19445	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC769_19505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC769_19530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC769_19800	COG2205	protein histidine kinase activity
IC769_19815	COG2132	Multicopper oxidase
IC769_19830	COG3328	transposase activity
IC769_19890	COG0789	Transcriptional regulator
IC769_20090	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC769_20125	COG2184	nucleotidyltransferase activity
IC769_20210	COG4221	oxidoreductase activity
IC769_20215	COG0583	DNA-binding transcription factor activity
IC769_20220	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC769_20225	COG3321	synthase
IC769_20225	COG0604	alcohol dehydrogenase
IC769_20235	COG0697	spore germination
IC769_20270	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC769_20285	COG1979	alcohol dehydrogenase
IC769_20295	COG1902	pentaerythritol trinitrate reductase activity
IC769_20305	COG1309	transcriptional regulator