locus-tag	class	description
IC770_00010	COG0592	DNA-directed DNA polymerase activity
IC770_00020	COG0187	DNA topoisomerase II activity
IC770_00030	COG0586	Pfam SNARE associated Golgi protein
IC770_00035	COG0488	(ABC) transporter
IC770_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC770_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC770_00105	COG0625	glutathione transferase activity
IC770_00115	COG0733	neurotransmitter:sodium symporter activity
IC770_00155	COG2233	PERMEase
IC770_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_00205	COG2814	Major facilitator Superfamily
IC770_00210	COG0656	L-ascorbic acid biosynthetic process
IC770_00215	COG0583	DNA-binding transcription factor activity
IC770_00235	COG1064	alcohol dehydrogenase
IC770_00255	COG1194	a g-specific adenine glycosylase
IC770_00270	COG5487	UPF0391 membrane protein
IC770_00275	COG2983	Belongs to the UPF0260 family
IC770_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC770_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC770_00315	COG1335	isochorismatase
IC770_00320	COG0385	Bile acid
IC770_00325	COG0534	Mate efflux family protein
IC770_00330	COG1683	Conserved Protein
IC770_00345	COG0346	lactoylglutathione lyase activity
IC770_00350	COG0625	glutathione transferase activity
IC770_00360	COG1113	amino acid transport
IC770_00370	COG0523	cobalamin synthesis protein
IC770_00380	COG2188	Transcriptional regulator
IC770_00410	COG0010	Belongs to the arginase family
IC770_00420	COG0546	phosphoglycolate phosphatase activity
IC770_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC770_00430	COG1280	lysine exporter protein (LysE YggA)
IC770_00460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC770_00470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC770_00475	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC770_00570	COG0534	Mate efflux family protein
IC770_00575	COG0436	Aminotransferase
IC770_00580	COG2733	membrane
IC770_00595	COG2918	glutathione biosynthetic process
IC770_00650	COG3150	esterase
IC770_00660	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC770_00670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC770_00685	COG2351	hydroxyisourate hydrolase activity
IC770_00705	COG0666	response to abiotic stimulus
IC770_00705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC770_00720	COG3706	GGDEF domain
IC770_00735	COG1393	Belongs to the ArsC family
IC770_00740	COG0708	Exodeoxyribonuclease III
IC770_00765	COG0189	ligase activity
IC770_00785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC770_00795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC770_00810	COG4942	peptidase
IC770_00820	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC770_00830	COG2119	membrane
IC770_00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC770_00835	COG0426	domain, Protein
IC770_00880	COG1902	pentaerythritol trinitrate reductase activity
IC770_00890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC770_00895	COG0668	transmembrane transport
IC770_00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC770_00910	COG1335	isochorismatase
IC770_00915	COG1522	sequence-specific DNA binding
IC770_00940	COG0784	Response regulator, receiver
IC770_00940	COG2198	Histidine kinase
IC770_00940	COG2205	protein histidine kinase activity
IC770_00945	COG3162	membrane
IC770_00950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC770_00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC770_00980	COG1309	transcriptional regulator
IC770_01010	COG0352	thiamine-phosphate diphosphorylase activity
IC770_01010	COG0351	phosphomethylpyrimidine kinase
IC770_01010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC770_01020	COG2814	Major facilitator Superfamily
IC770_01035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC770_01045	COG1113	amino acid transport
IC770_01055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC770_01060	COG1012	belongs to the aldehyde dehydrogenase family
IC770_01070	COG1335	isochorismatase
IC770_01105	COG2814	Major facilitator Superfamily
IC770_01110	COG0583	DNA-binding transcription factor activity
IC770_01130	COG0667	Aldo Keto reductase
IC770_01150	COG1733	regulation of RNA biosynthetic process
IC770_01175	COG1733	regulation of RNA biosynthetic process
IC770_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC770_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC770_01290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC770_01320	COG0427	acetyl-CoA hydrolase
IC770_01350	COG0659	secondary active sulfate transmembrane transporter activity
IC770_01355	COG4221	oxidoreductase activity
IC770_01365	COG0028	Belongs to the TPP enzyme family
IC770_01370	COG0488	(ABC) transporter
IC770_01485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC770_01490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC770_01505	COG2226	methyltransferase
IC770_01555	COG0067	glutamate synthase
IC770_01555	COG0070	glutamate synthase
IC770_01555	COG0069	glutamate synthase activity
IC770_01560	COG0493	'glutamate synthase
IC770_01570	COG1704	LemA family
IC770_01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC770_01585	COG4969	Belongs to the N-Me-Phe pilin family
IC770_01595	COG3307	-O-antigen
IC770_01615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC770_01630	COG0194	GDP metabolic process
IC770_01645	COG4969	Belongs to the N-Me-Phe pilin family
IC770_01670	COG4969	Belongs to the N-Me-Phe pilin family
IC770_01685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC770_01695	COG0335	large ribosomal subunit rRNA binding
IC770_01705	COG5380	lipid catabolic process
IC770_01710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC770_01735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC770_01750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC770_01755	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC770_01770	COG1289	transmembrane transporter activity
IC770_01780	COG0628	permease
IC770_01785	COG1192	Involved in chromosome partitioning
IC770_01815	COG0833	amino acid
IC770_01820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC770_01825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC770_01835	COG1012	belongs to the aldehyde dehydrogenase family
IC770_01875	COG0583	DNA-binding transcription factor activity
IC770_01880	COG1794	racemase activity, acting on amino acids and derivatives
IC770_01885	COG0583	DNA-binding transcription factor activity
IC770_01905	COG0752	glycyl-tRNA synthetase alpha subunit
IC770_01930	COG0617	tRNA 3'-terminal CCA addition
IC770_01930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC770_01930	COG0517	IMP dehydrogenase activity
IC770_01935	COG1983	PspC domain protein
IC770_01945	COG1960	acyl-CoA dehydrogenase activity
IC770_01960	COG0408	coproporphyrinogen oxidase activity
IC770_01980	COG0513	Belongs to the DEAD box helicase family
IC770_01985	COG1127	ABC transporter
IC770_01990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC770_02000	COG2854	intermembrane phospholipid transfer
IC770_02010	COG0598	Magnesium transport protein CorA
IC770_02020	COG0494	nUDIX hydrolase
IC770_02025	COG1040	competence protein
IC770_02030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC770_02050	COG1946	Acyl-CoA thioesterase
IC770_02055	COG1301	dicarboxylic acid transport
IC770_02070	COG1959	2 iron, 2 sulfur cluster binding
IC770_02075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC770_02075	COG1017	nitric oxide dioxygenase activity
IC770_02080	COG0433	COG0433 Predicted ATPase
IC770_02085	COG0626	cystathionine gamma-synthase activity
IC770_02100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC770_02105	COG0088	Forms part of the polypeptide exit tunnel
IC770_02240	COG1960	acyl-CoA dehydrogenase activity
IC770_02245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC770_02275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC770_02280	COG0339	signal peptide processing
IC770_02330	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC770_02335	COG2169	Transcriptional regulator
IC770_02345	COG1295	ribonuclease BN
IC770_02380	COG1702	phosphate starvation-inducible protein PhoH
IC770_02390	COG0739	heme binding
IC770_02390	COG1196	nuclear chromosome segregation
IC770_02390	COG0741	lytic transglycosylase activity
IC770_02420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC770_02425	COG1183	phosphatidylcholine synthase activity
IC770_02490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC770_02495	COG1309	transcriptional regulator
IC770_02510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC770_02515	COG1960	acyl-CoA dehydrogenase activity
IC770_02520	COG1024	Enoyl-CoA hydratase
IC770_02520	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC770_02555	COG2969	positive regulation of protein catabolic process
IC770_02565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC770_02575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC770_02580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC770_02605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC770_02615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC770_02620	COG1408	metallophosphoesterase
IC770_02630	COG2199	diguanylate cyclase activity
IC770_02665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC770_02690	COG1607	acyl-coa hydrolase
IC770_02725	COG2350	Protein conserved in bacteria
IC770_02735	COG0613	PHP domain protein
IC770_02740	COG3781	membrane
IC770_02750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC770_02755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC770_02765	COG1862	Preprotein translocase
IC770_02800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC770_02810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC770_02825	COG2194	sulfuric ester hydrolase activity
IC770_02835	COG0726	polysaccharide deacetylase
IC770_02840	COG0463	Glycosyl transferase, family 2
IC770_02845	COG0438	transferase activity, transferring glycosyl groups
IC770_02885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC770_02920	COG1960	acyl-CoA dehydrogenase activity
IC770_02925	COG1960	acyl-CoA dehydrogenase activity
IC770_02935	COG2205	protein histidine kinase activity
IC770_02940	COG0745	RESPONSE REGULATOR receiver
IC770_02950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC770_02970	COG2096	Adenosyltransferase
IC770_02975	COG4206	TonB-dependent receptor
IC770_03045	COG0450	alkyl hydroperoxide reductase
IC770_03060	COG0477	Major facilitator Superfamily
IC770_03065	COG1272	protein, Hemolysin III
IC770_03075	COG2153	protein acetylation
IC770_03100	COG2207	Transcriptional regulator
IC770_03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC770_03145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC770_03145	COG2885	chlorophyll binding
IC770_03155	COG1690	Belongs to the RtcB family
IC770_03160	COG0833	amino acid
IC770_03170	COG2233	PERMEase
IC770_03175	COG1217	gtp-binding protein TYPA
IC770_03205	COG4772	TonB-dependent receptor
IC770_03210	COG1902	pentaerythritol trinitrate reductase activity
IC770_03215	COG0679	Auxin Efflux Carrier
IC770_03225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC770_03230	COG0354	folic acid binding
IC770_03250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC770_03255	COG0251	oxidation-reduction process
IC770_03260	COG1335	isochorismatase
IC770_03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC770_03275	COG0596	Alpha beta hydrolase
IC770_03280	COG3189	MarR family transcriptional regulator
IC770_03285	COG2824	Alkylphosphonate utilization operon protein PhnA
IC770_03290	COG3422	double-strand break repair
IC770_03330	COG0840	transmembrane signaling receptor activity
IC770_03345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC770_03370	COG2832	Protein of unknown function (DUF454)
IC770_03375	COG1376	ErfK ybiS ycfS ynhG family protein
IC770_03425	COG1289	transmembrane transporter activity
IC770_03430	COG2814	Major facilitator Superfamily
IC770_03450	COG1115	amino acid carrier protein
IC770_03455	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC770_03460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC770_03465	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC770_03495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC770_03505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC770_03510	COG1077	Cell shape determining protein MreB Mrl
IC770_03515	COG1792	Involved in formation and maintenance of cell shape
IC770_03520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC770_03525	COG0424	maF-like protein
IC770_03530	COG1530	ribonuclease E activity
IC770_03540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC770_03560	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC770_03585	COG2207	Transcriptional regulator
IC770_03615	COG3046	protein related to deoxyribodipyrimidine photolyase
IC770_03620	COG2816	NAD+ diphosphatase activity
IC770_03625	COG1113	amino acid transport
IC770_03630	COG2828	Protein conserved in bacteria
IC770_03635	COG0142	geranyltranstransferase activity
IC770_03640	COG2315	Protein conserved in bacteria
IC770_03655	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC770_03675	COG2194	sulfuric ester hydrolase activity
IC770_03680	COG0745	RESPONSE REGULATOR receiver
IC770_03685	COG0642	Histidine kinase
IC770_03695	COG0004	ammonium transporteR
IC770_03700	COG0583	DNA-binding transcription factor activity
IC770_03720	COG0525	valine-tRNA ligase activity
IC770_03730	COG0525	valine-tRNA ligase activity
IC770_03740	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_03750	COG0393	Putative heavy-metal-binding
IC770_03755	COG0393	Putative heavy-metal-binding
IC770_03760	COG1538	Outer membrane efflux protein
IC770_03770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_03775	COG0671	phosphoesterase, PA-phosphatase related
IC770_03805	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC770_03820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC770_03820	COG1648	precorrin-2 dehydrogenase activity
IC770_03825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC770_03830	COG1733	regulation of RNA biosynthetic process
IC770_03840	COG0531	amino acid
IC770_03855	COG0321	lipoyl(octanoyl) transferase activity
IC770_03860	COG2921	Belongs to the UPF0250 family
IC770_03895	COG2009	succinate dehydrogenase
IC770_03900	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC770_03905	COG1053	succinate dehydrogenase
IC770_03910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC770_03955	COG2354	Protein conserved in bacteria
IC770_03960	COG2321	neutral zinc metallopeptidase
IC770_03985	COG2843	Capsule synthesis protein
IC770_04005	COG0589	response to stress
IC770_04025	COG0505	Belongs to the CarA family
IC770_04050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC770_04055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC770_04105	COG0477	Major facilitator Superfamily
IC770_04110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC770_04125	COG1597	lipid kinase activity
IC770_04150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC770_04155	COG0584	glycerophosphoryl diester phosphodiesterase
IC770_04175	COG0741	lytic transglycosylase activity
IC770_04200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC770_04270	COG0644	oxidoreductase
IC770_04270	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC770_04275	COG1960	acyl-CoA dehydrogenase activity
IC770_04280	COG1024	Enoyl-CoA hydratase
IC770_04285	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC770_04290	COG0183	Belongs to the thiolase family
IC770_04295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC770_04315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_04320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC770_04335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC770_04355	COG3811	Belongs to the UPF0386 family
IC770_04420	COG1902	pentaerythritol trinitrate reductase activity
IC770_04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC770_04425	COG0596	Alpha beta hydrolase
IC770_04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC770_04430	COG0596	Alpha beta hydrolase
IC770_04435	COG0596	Alpha beta hydrolase
IC770_04440	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_04445	COG0583	DNA-binding transcription factor activity
IC770_04450	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC770_04455	COG1012	belongs to the aldehyde dehydrogenase family
IC770_04480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_04485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC770_04490	COG0778	Nitroreductase
IC770_04505	COG1929	Belongs to the glycerate kinase type-1 family
IC770_04510	COG0243	molybdopterin cofactor binding
IC770_04515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC770_04520	COG3339	Conserved Protein
IC770_04550	COG1113	amino acid transport
IC770_04560	COG0019	diaminopimelate decarboxylase activity
IC770_04575	COG1280	lysine exporter protein (LysE YggA)
IC770_04600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC770_04610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC770_04620	COG0463	Glycosyl transferase, family 2
IC770_04640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_04680	COG1136	(ABC) transporter
IC770_04695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC770_04695	COG0616	signal peptide processing
IC770_04700	COG0596	Alpha beta hydrolase
IC770_04705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC770_04715	COG0628	permease
IC770_04750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC770_04770	COG0823	Involved in the tonB-independent uptake of proteins
IC770_04790	COG0824	Thioesterase
IC770_04795	COG1473	amidohydrolase
IC770_04845	COG1024	Enoyl-CoA hydratase
IC770_04850	COG1051	belongs to the nudix hydrolase family
IC770_04850	COG1056	cytidyltransferase-related domain
IC770_04865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC770_04880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC770_04885	COG0602	queuosine metabolic process
IC770_04895	COG4625	pathogenesis
IC770_04900	COG0583	DNA-binding transcription factor activity
IC770_04905	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC770_04910	COG4208	sulfate ABC transporter
IC770_04915	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC770_04925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC770_04935	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC770_04955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC770_04985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC770_04995	COG1381	Involved in DNA repair and RecF pathway recombination
IC770_05000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC770_05010	COG4221	oxidoreductase activity
IC770_05035	COG0436	Aminotransferase
IC770_05060	COG0556	nucleotide-excision repair
IC770_05115	COG2070	2-Nitropropane dioxygenase
IC770_05130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC770_05145	COG1215	transferase activity, transferring glycosyl groups
IC770_05160	COG0415	Belongs to the DNA photolyase family
IC770_05170	COG1252	NADH dehydrogenase
IC770_05175	COG1686	Belongs to the peptidase S11 family
IC770_05190	COG1187	pseudouridine synthase activity
IC770_05275	COG3728	DNA packaging
IC770_05275	COG5484	DNA packaging
IC770_05385	COG0739	heme binding
IC770_05385	COG0741	lytic transglycosylase activity
IC770_05385	COG1196	nuclear chromosome segregation
IC770_05455	COG0477	Major facilitator Superfamily
IC770_05460	COG0583	DNA-binding transcription factor activity
IC770_05465	COG1823	symporter activity
IC770_05475	COG0612	Peptidase, M16
IC770_05500	COG0352	thiamine-phosphate diphosphorylase activity
IC770_05535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC770_05560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC770_05565	COG0076	glutamate decarboxylase activity
IC770_05585	COG1113	amino acid transport
IC770_05590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC770_05595	COG0573	inorganic phosphate transmembrane transporter activity
IC770_05605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC770_05625	COG3647	Membrane
IC770_05650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC770_05655	COG1686	Belongs to the peptidase S11 family
IC770_05680	COG0583	DNA-binding transcription factor activity
IC770_05685	COG1067	ATP-dependent peptidase activity
IC770_05710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC770_05725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC770_05730	COG1966	Carbon starvation protein
IC770_05735	COG2879	small protein
IC770_05765	COG2814	Major facilitator Superfamily
IC770_05805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC770_05810	COG2423	ornithine cyclodeaminase activity
IC770_05825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC770_05835	COG1741	Belongs to the pirin family
IC770_05850	COG3739	integral membrane protein
IC770_05870	COG0302	gtp cyclohydrolase
IC770_05880	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC770_05890	COG2840	Smr protein MutS2
IC770_05905	COG0512	Glutamine amidotransferase of anthranilate synthase
IC770_05920	COG0174	glutamine synthetase
IC770_05965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC770_05970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC770_05975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC770_06000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC770_06020	COG1960	acyl-CoA dehydrogenase activity
IC770_06025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC770_06030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC770_06050	COG0024	Methionine aminopeptidase
IC770_06055	COG0052	Belongs to the universal ribosomal protein uS2 family
IC770_06095	COG2951	lytic endotransglycosylase activity
IC770_06100	COG0772	Belongs to the SEDS family
IC770_06115	COG0842	Transport permease protein
IC770_06120	COG1131	(ABC) transporter
IC770_06125	COG0582	viral genome integration into host DNA
IC770_06450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_06465	COG4215	(ABC) transporter
IC770_06470	COG4160	amino acid transport
IC770_06475	COG4598	ABC transporter
IC770_06485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC770_06490	COG0826	peptidase U32
IC770_06495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC770_06500	COG0384	phenazine biosynthesis protein PhzF
IC770_06510	COG1720	tRNA m6t6A37 methyltransferase activity
IC770_06520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC770_06535	COG0642	Histidine kinase
IC770_06545	COG0494	nUDIX hydrolase
IC770_06555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC770_06560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC770_06565	COG3139	Protein of unknown function (DUF1315)
IC770_06575	COG1301	dicarboxylic acid transport
IC770_06580	COG1960	acyl-CoA dehydrogenase activity
IC770_06600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC770_06610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC770_06615	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC770_06635	COG1690	Belongs to the RtcB family
IC770_06640	COG1234	tRNA 3'-trailer cleavage
IC770_06645	COG4650	regulator
IC770_06670	COG2363	Small membrane protein
IC770_06690	COG0513	Belongs to the DEAD box helicase family
IC770_06700	COG0778	Nitroreductase
IC770_06760	COG1610	YqeY-like protein
IC770_06790	COG0515	serine threonine protein kinase
IC770_06790	COG2815	serine threonine protein kinase
IC770_06895	COG1335	isochorismatase
IC770_06900	COG0583	DNA-binding transcription factor activity
IC770_06920	COG0596	Alpha beta hydrolase
IC770_06940	COG0786	glutamate:sodium symporter activity
IC770_06945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC770_06945	COG0475	glutathione-regulated potassium exporter activity
IC770_06950	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_07025	COG1309	transcriptional regulator
IC770_07050	COG2985	domain, Protein
IC770_07075	COG2995	paraquat-inducible protein a
IC770_07080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC770_07080	COG3008	intermembrane lipid transfer
IC770_07090	COG2351	hydroxyisourate hydrolase activity
IC770_07105	COG5002	protein histidine kinase activity
IC770_07130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC770_07140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC770_07145	COG0642	Histidine kinase
IC770_07150	COG0745	RESPONSE REGULATOR receiver
IC770_07175	COG2175	clavaminate synthase activity
IC770_07180	COG3246	L-lysine catabolic process to acetate
IC770_07185	COG2814	Major facilitator Superfamily
IC770_07200	COG2855	membrane
IC770_07245	COG1301	dicarboxylic acid transport
IC770_07260	COG2011	ABC-type metal ion transport system permease component
IC770_07265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC770_07270	COG1464	Belongs to the NlpA lipoprotein family
IC770_07280	COG0138	bifunctional purine biosynthesis protein purh
IC770_07285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC770_07315	COG2308	Evidence 4 Homologs of previously reported genes of
IC770_07325	COG1305	Transglutaminase-like
IC770_07335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC770_07340	COG0305	Participates in initiation and elongation during chromosome replication
IC770_07365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC770_07375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC770_07410	COG1215	transferase activity, transferring glycosyl groups
IC770_07415	COG3658	cytochrome
IC770_07425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC770_07445	COG2890	protein-(glutamine-N5) methyltransferase activity
IC770_07450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC770_07455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC770_07475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC770_07480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC770_07505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC770_07510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC770_07515	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC770_07520	COG2205	protein histidine kinase activity
IC770_07525	COG0745	RESPONSE REGULATOR receiver
IC770_07550	COG0729	surface antigen
IC770_07580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC770_07585	COG2814	Major facilitator Superfamily
IC770_07595	COG0583	DNA-binding transcription factor activity
IC770_07610	COG1187	pseudouridine synthase activity
IC770_07630	COG0802	atpase or kinase
IC770_07635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC770_07645	COG1923	regulation of RNA biosynthetic process
IC770_07650	COG0697	spore germination
IC770_07675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC770_07680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC770_07680	COG0519	Catalyzes the synthesis of GMP from XMP
IC770_07685	COG4302	ethanolamine ammonia-lyase activity
IC770_07690	COG4303	Ethanolamine ammonia lyase large subunit
IC770_07695	COG0531	amino acid
IC770_07715	COG1454	alcohol dehydrogenase
IC770_07720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC770_07730	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC770_07750	COG0308	aminopeptidase N
IC770_07780	COG0625	glutathione transferase activity
IC770_07795	COG1605	Chorismate mutase
IC770_07845	COG4264	IucA IucC family
IC770_07855	COG4264	IucA IucC family
IC770_07865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC770_07875	COG0668	transmembrane transport
IC770_07925	COG0589	response to stress
IC770_07950	COG3135	benzoate transporter
IC770_07955	COG1522	sequence-specific DNA binding
IC770_07965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC770_07970	COG0583	DNA-binding transcription factor activity
IC770_07980	COG0183	Belongs to the thiolase family
IC770_07985	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_07990	COG2030	dehydratase
IC770_07995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC770_08020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC770_08035	COG0824	Thioesterase
IC770_08040	COG1454	alcohol dehydrogenase
IC770_08050	COG1335	isochorismatase
IC770_08065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC770_08095	COG0069	glutamate synthase activity
IC770_08140	COG2814	Major facilitator Superfamily
IC770_08155	COG0511	ligase activity, forming carbon-carbon bonds
IC770_08175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC770_08175	COG1116	anion transmembrane transporter activity
IC770_08180	COG0745	RESPONSE REGULATOR receiver
IC770_08190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC770_08190	COG2146	nitrite reductase [NAD(P)H] activity
IC770_08195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC770_08200	COG0243	molybdopterin cofactor binding
IC770_08210	COG0243	molybdopterin cofactor binding
IC770_08215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC770_08230	COG0315	cyclic pyranopterin monophosphate synthase activity
IC770_08230	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC770_08235	COG0303	'Molybdopterin
IC770_08245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC770_08270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC770_08275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC770_08330	COG2204	response regulator
IC770_08335	COG3852	Histidine kinase
IC770_08360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC770_08365	COG0575	Belongs to the CDS family
IC770_08380	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC770_08400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC770_08415	COG2137	regulation of response to DNA damage stimulus
IC770_08425	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC770_08430	COG1011	Hydrolase
IC770_08445	COG1522	sequence-specific DNA binding
IC770_08455	COG1113	amino acid transport
IC770_08470	COG0659	secondary active sulfate transmembrane transporter activity
IC770_08485	COG5001	Diguanylate cyclase
IC770_08485	COG3300	MHYT domain
IC770_08505	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC770_08505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC770_08505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC770_08510	COG1105	Belongs to the carbohydrate kinase PfkB family
IC770_08515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC770_08515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC770_08545	COG0024	Methionine aminopeptidase
IC770_08550	COG0583	DNA-binding transcription factor activity
IC770_08560	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC770_08565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC770_08570	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC770_08595	COG0552	protein localization to endoplasmic reticulum
IC770_08620	COG4890	Cyd operon protein YbgT
IC770_08625	COG1294	oxidase, subunit
IC770_08640	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC770_08650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC770_08655	COG4774	siderophore transport
IC770_08670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC770_08675	COG0569	domain protein
IC770_08680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC770_08710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC770_08715	COG0542	response to heat
IC770_08740	COG1902	pentaerythritol trinitrate reductase activity
IC770_08740	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC770_08780	COG0148	phosphopyruvate hydratase activity
IC770_08795	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC770_08805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC770_08810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC770_08815	COG0183	Belongs to the thiolase family
IC770_08825	COG0596	Alpha beta hydrolase
IC770_08830	COG2271	Major facilitator Superfamily
IC770_08835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC770_08840	COG3485	protocatechuate 3,4-dioxygenase
IC770_08845	COG3485	protocatechuate 3,4-dioxygenase
IC770_08855	COG3420	alginic acid biosynthetic process
IC770_08865	COG4993	Dehydrogenase
IC770_08875	COG2391	methyltransferase activity
IC770_08890	COG1414	Transcriptional regulator
IC770_08895	COG0583	DNA-binding transcription factor activity
IC770_08900	COG1960	acyl-CoA dehydrogenase activity
IC770_08925	COG2814	Major facilitator Superfamily
IC770_08935	COG0154	amidase activity
IC770_08955	COG4638	Rieske (2fe-2S)
IC770_08975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC770_08985	COG3733	amine oxidase
IC770_09000	COG1012	belongs to the aldehyde dehydrogenase family
IC770_09005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC770_09010	COG0183	Belongs to the thiolase family
IC770_09015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC770_09020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC770_09030	COG4829	muconolactone delta-isomerase
IC770_09035	COG4948	Mandelate Racemase Muconate Lactonizing
IC770_09040	COG0583	DNA-binding transcription factor activity
IC770_09095	COG1309	transcriptional regulator
IC770_09175	COG2188	Transcriptional regulator
IC770_09190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC770_09205	COG2271	Major facilitator Superfamily
IC770_09215	COG1566	PFAM secretion protein HlyD family protein
IC770_09245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC770_09250	COG1120	ATPase activity
IC770_09270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC770_09390	COG2175	clavaminate synthase activity
IC770_09395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC770_09410	COG0667	Aldo Keto reductase
IC770_09415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC770_09430	COG2175	clavaminate synthase activity
IC770_09470	COG4771	TonB-dependent receptor
IC770_09500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC770_09510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC770_09515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC770_09530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC770_09545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC770_09565	COG1132	(ABC) transporter
IC770_09590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC770_09595	COG0601	transmembrane transport
IC770_09625	COG3539	Fimbrial protein
IC770_09650	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC770_09670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC770_09675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC770_09690	COG0745	RESPONSE REGULATOR receiver
IC770_09695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC770_09700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC770_09760	COG4771	TonB-dependent receptor
IC770_09770	COG3433	isochorismatase activity
IC770_09770	COG1535	isochorismatase
IC770_09780	COG1169	isochorismate synthase
IC770_09785	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_09795	COG3251	PFAM MbtH domain protein
IC770_09800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC770_09825	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC770_09830	COG4149	molybdate abc transporter
IC770_09835	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC770_09845	COG4638	Rieske (2fe-2S)
IC770_09850	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC770_09855	COG0543	2 iron, 2 sulfur cluster binding
IC770_09855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC770_09870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC770_09880	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_09900	COG2207	Transcriptional regulator
IC770_09905	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_09910	COG2610	gluconate transmembrane transporter activity
IC770_09915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC770_09945	COG2814	Major facilitator Superfamily
IC770_09970	COG0583	DNA-binding transcription factor activity
IC770_09985	COG2031	fatty acid transporter
IC770_09990	COG0183	Belongs to the thiolase family
IC770_09995	COG0583	DNA-binding transcription factor activity
IC770_10000	COG0583	DNA-binding transcription factor activity
IC770_10015	COG1027	Aspartate ammonia-lyase
IC770_10025	COG0477	Major facilitator Superfamily
IC770_10035	COG2207	Transcriptional regulator
IC770_10035	COG3708	Transcriptional regulator
IC770_10050	COG0730	response to heat
IC770_10060	COG3453	Protein conserved in bacteria
IC770_10060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC770_10070	COG3781	membrane
IC770_10075	COG1063	alcohol dehydrogenase
IC770_10085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC770_10090	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC770_10095	COG0022	dehydrogenase e1 component
IC770_10100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC770_10105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC770_10120	COG3706	GGDEF domain
IC770_10135	COG0133	tryptophan synthase activity
IC770_10145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC770_10190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC770_10215	COG2226	methyltransferase
IC770_10265	COG0842	Transport permease protein
IC770_10270	COG0842	Transport permease protein
IC770_10275	COG1131	(ABC) transporter
IC770_10290	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC770_10295	COG4773	Receptor
IC770_10315	COG0730	response to heat
IC770_10320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC770_10335	COG0406	alpha-ribazole phosphatase activity
IC770_10340	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC770_10375	COG1960	acyl-CoA dehydrogenase activity
IC770_10380	COG1960	acyl-CoA dehydrogenase activity
IC770_10385	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC770_10390	COG2207	Transcriptional regulator
IC770_10400	COG0776	regulation of translation
IC770_10425	COG0822	iron-sulfur transferase activity
IC770_10430	COG0316	Belongs to the HesB IscA family
IC770_10480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC770_10485	COG0702	epimerase
IC770_10515	COG4172	Belongs to the ABC transporter superfamily
IC770_10520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC770_10525	COG0601	transmembrane transport
IC770_10550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC770_10575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC770_10695	COG4695	Portal protein
IC770_10775	COG0305	Participates in initiation and elongation during chromosome replication
IC770_10790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC770_10835	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC770_10850	COG2431	L-lysine efflux transmembrane transporter activity
IC770_10865	COG0776	regulation of translation
IC770_10930	COG0084	hydrolase, TatD family'
IC770_10955	COG1132	(ABC) transporter
IC770_10965	COG0811	peptide transport
IC770_10970	COG1475	DNA binding
IC770_10975	COG1192	Involved in chromosome partitioning
IC770_10985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC770_11025	COG0424	maF-like protein
IC770_11030	COG2850	peptidyl-arginine hydroxylation
IC770_11050	COG3619	membrane
IC770_11055	COG3122	Protein conserved in bacteria
IC770_11060	COG1132	(ABC) transporter
IC770_11080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC770_11085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC770_11095	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC770_11095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC770_11095	COG0506	proline dehydrogenase activity
IC770_11100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC770_11115	COG3698	Phosphodiester glycosidase
IC770_11125	COG2353	YceI-like domain
IC770_11140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC770_11180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC770_11180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC770_11205	COG3539	Fimbrial protein
IC770_11210	COG3121	Chaperone
IC770_11230	COG0697	spore germination
IC770_11240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC770_11250	COG0583	DNA-binding transcription factor activity
IC770_11270	COG2197	response regulator
IC770_11295	COG1522	sequence-specific DNA binding
IC770_11305	COG1126	abc transporter atp-binding protein
IC770_11310	COG0765	amino acid transport
IC770_11315	COG0765	amino acid transport
IC770_11345	COG1464	Belongs to the NlpA lipoprotein family
IC770_11355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC770_11360	COG2011	ABC-type metal ion transport system permease component
IC770_11365	COG0012	GTP binding
IC770_11390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC770_11425	COG1917	Cupin 2, conserved barrel domain protein
IC770_11425	COG2207	Transcriptional regulator
IC770_11430	COG0386	Belongs to the glutathione peroxidase family
IC770_11440	COG0436	Aminotransferase
IC770_11480	COG3634	alkyl hydroperoxide reductase activity
IC770_11495	COG0583	DNA-binding transcription factor activity
IC770_11500	COG0431	NADPH-dependent FMN reductase
IC770_11505	COG0798	PFAM Bile acid sodium symporter
IC770_11510	COG0640	Transcriptional regulator
IC770_11525	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC770_11535	COG0583	DNA-binding transcription factor activity
IC770_11545	COG1953	Uracil, thiamine, allantoin
IC770_11555	COG2175	clavaminate synthase activity
IC770_11560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC770_11565	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC770_11580	COG0477	Major facilitator Superfamily
IC770_11600	COG1271	oxidase subunit
IC770_11605	COG1294	oxidase, subunit
IC770_11615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC770_11635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC770_11655	COG3052	prosthetic group binding
IC770_11660	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC770_11685	COG1346	cytolysis
IC770_11705	COG0625	glutathione transferase activity
IC770_11710	COG0583	DNA-binding transcription factor activity
IC770_11730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC770_11735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC770_11740	COG1280	lysine exporter protein (LysE YggA)
IC770_11750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC770_11765	COG0765	amino acid transport
IC770_11770	COG0765	amino acid transport
IC770_11830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC770_11850	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_11895	COG0583	DNA-binding transcription factor activity
IC770_11915	COG0318	PFAM AMP-dependent synthetase and ligase
IC770_11920	COG1309	transcriptional regulator
IC770_11925	COG1960	acyl-CoA dehydrogenase activity
IC770_11930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC770_11940	COG4770	biotin carboxylase activity
IC770_11950	COG0583	DNA-binding transcription factor activity
IC770_11965	COG1960	acyl-CoA dehydrogenase activity
IC770_11975	COG2814	Major facilitator Superfamily
IC770_11985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC770_11995	COG2814	Major facilitator Superfamily
IC770_12000	COG1960	acyl-CoA dehydrogenase activity
IC770_12005	COG1024	Enoyl-CoA hydratase
IC770_12015	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC770_12020	COG0183	Belongs to the thiolase family
IC770_12030	COG2814	Major facilitator Superfamily
IC770_12045	COG1024	Enoyl-CoA hydratase
IC770_12055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC770_12060	COG1960	acyl-CoA dehydrogenase activity
IC770_12065	COG2814	Major facilitator Superfamily
IC770_12070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC770_12075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC770_12110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC770_12115	COG1414	Transcriptional regulator
IC770_12125	COG0583	DNA-binding transcription factor activity
IC770_12140	COG3038	cytochrome b561
IC770_12145	COG0753	catalase activity
IC770_12150	COG0531	amino acid
IC770_12155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC770_12175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC770_12180	COG1309	transcriptional regulator
IC770_12220	COG3179	chitinase
IC770_12240	COG0406	alpha-ribazole phosphatase activity
IC770_12250	COG2050	protein possibly involved in aromatic compounds catabolism
IC770_12260	COG3327	negative regulation of DNA-templated transcription, initiation
IC770_12265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC770_12280	COG1024	Enoyl-CoA hydratase
IC770_12285	COG1024	Enoyl-CoA hydratase
IC770_12290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC770_12295	COG2151	metal-sulfur cluster biosynthetic enzyme
IC770_12300	COG3396	Phenylacetate-CoA oxygenase
IC770_12305	COG3460	Phenylacetate-CoA oxygenase
IC770_12310	COG3396	Phenylacetate-CoA oxygenase
IC770_12330	COG0789	Transcriptional regulator
IC770_12340	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC770_12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC770_12360	COG2807	transmembrane transport
IC770_12365	COG0590	tRNA wobble adenosine to inosine editing
IC770_12470	COG0477	Major facilitator Superfamily
IC770_12485	COG1116	anion transmembrane transporter activity
IC770_12490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC770_12500	COG0864	Transcriptional regulator
IC770_12515	COG1733	regulation of RNA biosynthetic process
IC770_12520	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC770_12540	COG1063	alcohol dehydrogenase
IC770_12585	COG0038	chloride channel
IC770_12590	COG4770	biotin carboxylase activity
IC770_12610	COG1914	H( )-stimulated, divalent metal cation uptake system
IC770_12615	COG0583	DNA-binding transcription factor activity
IC770_12625	COG1595	DNA-templated transcription, initiation
IC770_12635	COG3220	belongs to the UPF0276 family
IC770_12650	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_12665	COG2076	Multidrug Resistance protein
IC770_12680	COG3713	MltA-interacting MipA family protein
IC770_12685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC770_12730	COG3209	COG3209 Rhs family protein
IC770_12815	COG1309	transcriptional regulator
IC770_12820	COG1278	Cold shock
IC770_12830	COG0626	cystathionine gamma-synthase activity
IC770_12835	COG1522	sequence-specific DNA binding
IC770_12845	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_12855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC770_12860	COG4774	siderophore transport
IC770_12880	COG2814	Major facilitator Superfamily
IC770_12895	COG0402	S-adenosylhomocysteine deaminase activity
IC770_12900	COG0583	DNA-binding transcription factor activity
IC770_12915	COG1294	oxidase, subunit
IC770_12920	COG1469	GTP cyclohydrolase I activity
IC770_12985	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC770_12995	COG4122	O-methyltransferase activity
IC770_13025	COG1538	Outer membrane efflux protein
IC770_13030	COG1137	ATPase activity
IC770_13035	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC770_13045	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC770_13050	COG0517	IMP dehydrogenase activity
IC770_13050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC770_13070	COG0667	Aldo Keto reductase
IC770_13080	COG2814	Major facilitator Superfamily
IC770_13110	COG1278	Cold shock
IC770_13115	COG1280	lysine exporter protein (LysE YggA)
IC770_13145	COG1570	exodeoxyribonuclease VII activity
IC770_13230	COG2871	sodium ion transport
IC770_13240	COG0583	DNA-binding transcription factor activity
IC770_13250	COG4638	Rieske (2fe-2S)
IC770_13255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC770_13260	COG0543	2 iron, 2 sulfur cluster binding
IC770_13260	COG0633	Ferredoxin
IC770_13265	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_13270	COG3135	benzoate transporter
IC770_13275	COG2814	Major facilitator Superfamily
IC770_13290	COG1643	Atp-dependent helicase
IC770_13305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC770_13325	COG3634	alkyl hydroperoxide reductase activity
IC770_13345	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC770_13350	COG0625	glutathione transferase activity
IC770_13395	COG0542	response to heat
IC770_13410	COG1765	OsmC-like protein
IC770_13420	COG0667	Aldo Keto reductase
IC770_13435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC770_13450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC770_13460	COG0527	aspartate kinase activity
IC770_13480	COG3038	cytochrome b561
IC770_13485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC770_13490	COG2252	PERMEase
IC770_13500	COG2072	flavoprotein involved in K transport
IC770_13515	COG1741	Belongs to the pirin family
IC770_13520	COG1309	transcriptional regulator
IC770_13540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC770_13545	COG0583	DNA-binding transcription factor activity
IC770_13560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC770_13590	COG1944	ATP diphosphatase activity
IC770_13630	COG1024	Enoyl-CoA hydratase
IC770_13635	COG1012	belongs to the aldehyde dehydrogenase family
IC770_13645	COG1960	acyl-CoA dehydrogenase activity
IC770_13665	COG0697	spore germination
IC770_13705	COG1012	belongs to the aldehyde dehydrogenase family
IC770_13725	COG0531	amino acid
IC770_13735	COG1113	amino acid transport
IC770_13785	COG1846	Transcriptional regulator
IC770_13830	COG4269	membrane
IC770_13850	COG0583	DNA-binding transcription factor activity
IC770_13860	COG0251	oxidation-reduction process
IC770_13880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC770_13910	COG3152	Membrane
IC770_13960	COG0582	viral genome integration into host DNA
IC770_13970	COG1902	pentaerythritol trinitrate reductase activity
IC770_13970	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC770_13990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC770_14015	COG4172	Belongs to the ABC transporter superfamily
IC770_14020	COG4239	(ABC) transporter, permease
IC770_14025	COG4174	ABC transporter (Permease)
IC770_14035	COG1388	LysM domain
IC770_14035	COG0741	lytic transglycosylase activity
IC770_14080	COG0583	DNA-binding transcription factor activity
IC770_14105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC770_14110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC770_14115	COG0006	proline dipeptidase activity
IC770_14255	COG0681	Belongs to the peptidase S26 family
IC770_14290	COG4373	Mu-like prophage FluMu protein gp28
IC770_14300	COG4383	Mu-like prophage protein gp29
IC770_14305	COG2369	cell adhesion
IC770_14325	COG4397	Mu-like prophage major head subunit gpT
IC770_14465	COG3384	dioxygenase
IC770_14475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC770_14480	COG2878	Part of a membrane complex involved in electron transport
IC770_14485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC770_14510	COG0768	penicillin binding
IC770_14515	COG0742	ribosomal rna small subunit methyltransferase
IC770_14545	COG0804	urea catabolic process
IC770_14585	COG1253	flavin adenine dinucleotide binding
IC770_14590	COG2851	Citrate transporter
IC770_14640	COG1773	rubredoxin
IC770_14645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC770_14655	COG0583	DNA-binding transcription factor activity
IC770_14680	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC770_14685	COG4181	ATPase activity
IC770_14730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC770_14750	COG0306	phosphate transporter
IC770_14780	COG2223	nitrite transmembrane transporter activity
IC770_14785	COG2207	Transcriptional regulator
IC770_14790	COG2066	Belongs to the glutaminase family
IC770_14795	COG0242	peptide deformylase activity
IC770_14800	COG0477	Major facilitator Superfamily
IC770_14810	COG0028	Belongs to the TPP enzyme family
IC770_14825	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_14830	COG2267	carboxylic ester hydrolase activity
IC770_14875	COG1414	Transcriptional regulator
IC770_14905	COG1024	Enoyl-CoA hydratase
IC770_14915	COG1215	transferase activity, transferring glycosyl groups
IC770_14920	COG0726	polysaccharide deacetylase
IC770_14920	COG1649	PFAM Uncharacterised BCR, COG1649
IC770_14930	COG4681	YaeQ
IC770_14940	COG0523	cobalamin synthesis protein
IC770_14950	COG1607	acyl-coa hydrolase
IC770_14960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC770_14965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC770_14995	COG2040	homocysteine
IC770_15000	COG0531	amino acid
IC770_15020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC770_15065	COG3586	endonuclease activity
IC770_15130	COG0405	Gamma-glutamyltransferase
IC770_15135	COG2814	Major facilitator Superfamily
IC770_15145	COG2050	protein possibly involved in aromatic compounds catabolism
IC770_15160	COG1090	epimerase
IC770_15180	COG0420	3'-5' exonuclease activity
IC770_15190	COG1968	undecaprenyl-diphosphatase activity
IC770_15210	COG0735	belongs to the Fur family
IC770_15215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC770_15220	COG2914	Belongs to the UPF0125 (RnfH) family
IC770_15250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC770_15260	COG0210	DNA helicase
IC770_15265	COG2885	chlorophyll binding
IC770_15270	COG0204	Acyl-transferase
IC770_15285	COG2894	cell division
IC770_15300	COG1280	lysine exporter protein (LysE YggA)
IC770_15305	COG1674	ftsk spoiiie
IC770_15310	COG0492	ferredoxin-NADP+ reductase activity
IC770_15315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC770_15325	COG0456	acetyltransferase
IC770_15345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC770_15355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC770_15370	COG1981	membrane
IC770_15380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC770_15380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC770_15400	COG1012	belongs to the aldehyde dehydrogenase family
IC770_15405	COG4638	Rieske (2fe-2S)
IC770_15410	COG0657	acetylesterase activity
IC770_15420	COG0473	3-isopropylmalate dehydrogenase activity
IC770_15425	COG0583	DNA-binding transcription factor activity
IC770_15445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC770_15470	COG0564	pseudouridine synthase activity
IC770_15480	COG0358	DNA primase activity
IC770_15495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC770_15525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC770_15555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC770_15565	COG0351	phosphomethylpyrimidine kinase
IC770_15565	COG0352	thiamine-phosphate diphosphorylase activity
IC770_15565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC770_15570	COG1652	LysM domain
IC770_15595	COG1399	metal-binding, possibly nucleic acid-binding protein
IC770_15600	COG3101	peptidyl-lysine hydroxylation
IC770_15610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC770_15615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC770_15630	COG4106	trans-aconitate 2-methyltransferase activity
IC770_15645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC770_15645	COG2226	methyltransferase
IC770_15645	COG0596	Alpha beta hydrolase
IC770_15655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC770_15660	COG2223	nitrite transmembrane transporter activity
IC770_15680	COG1196	nuclear chromosome segregation
IC770_15690	COG0730	response to heat
IC770_15705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC770_15715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC770_15760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC770_15765	COG0489	protein tyrosine kinase activity
IC770_15775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC770_15775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC770_15810	COG2081	HI0933 family
IC770_15840	COG0583	DNA-binding transcription factor activity
IC770_15865	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC770_15870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC770_15885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC770_15900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC770_15925	COG3706	GGDEF domain
IC770_15940	COG0745	RESPONSE REGULATOR receiver
IC770_15960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC770_15990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC770_15995	COG0583	DNA-binding transcription factor activity
IC770_16045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC770_16060	COG0583	DNA-binding transcription factor activity
IC770_16070	COG0583	DNA-binding transcription factor activity
IC770_16090	COG1053	succinate dehydrogenase
IC770_16105	COG1309	transcriptional regulator
IC770_16115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC770_16120	COG2814	Major facilitator Superfamily
IC770_16125	COG1960	acyl-CoA dehydrogenase activity
IC770_16130	COG0583	DNA-binding transcription factor activity
IC770_16135	COG1063	alcohol dehydrogenase
IC770_16165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC770_16170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC770_16175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC770_16205	COG0561	phosphatase activity
IC770_16210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC770_16220	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC770_16235	COG1214	PFAM Peptidase M22, glycoprotease
IC770_16285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC770_16295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC770_16300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC770_16305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC770_16365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC770_16375	COG1846	Transcriptional regulator
IC770_16380	COG1764	response to oxidative stress
IC770_16430	COG0248	Ppx GppA phosphatase
IC770_16460	COG0072	phenylalanine-tRNA ligase activity
IC770_16490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC770_16500	COG1238	metal cluster binding
IC770_16505	COG0625	glutathione transferase activity
IC770_16520	COG0318	PFAM AMP-dependent synthetase and ligase
IC770_16525	COG3028	Belongs to the UPF0307 family
IC770_16550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC770_16555	COG0617	tRNA 3'-terminal CCA addition
IC770_16560	COG1555	photosystem II stabilization
IC770_16565	COG3956	TIGRFAM MazG family protein
IC770_16575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC770_16595	COG0784	Response regulator, receiver
IC770_16595	COG2205	protein histidine kinase activity
IC770_16595	COG5002	protein histidine kinase activity
IC770_16600	COG1024	Enoyl-CoA hydratase
IC770_16605	COG2084	Dehydrogenase
IC770_16610	COG3622	Belongs to the hyi family
IC770_16645	COG0697	spore germination
IC770_16655	COG2814	Major facilitator Superfamily
IC770_16695	COG2814	Major facilitator Superfamily
IC770_16805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC770_16815	COG0583	DNA-binding transcription factor activity
IC770_16825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC770_16835	COG0084	hydrolase, TatD family'
IC770_16850	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC770_16875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC770_16880	COG0440	acetolactate synthase activity
IC770_16885	COG0028	Belongs to the TPP enzyme family
IC770_16915	COG1136	(ABC) transporter
IC770_16915	COG0577	efflux transmembrane transporter activity
IC770_16920	COG1538	Outer membrane efflux protein
IC770_16935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC770_16940	COG1162	GTPase activity
IC770_16950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC770_16990	COG1426	Protein conserved in bacteria
IC770_17025	COG0793	Belongs to the peptidase S41A family
IC770_17050	COG1012	belongs to the aldehyde dehydrogenase family
IC770_17055	COG3265	gluconokinase activity
IC770_17065	COG0800	Aldolase
IC770_17075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC770_17080	COG0280	phosphate acetyltransferase
IC770_17080	COG0857	belongs to the CobB CobQ family
IC770_17085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC770_17085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC770_17105	COG0740	serine-type endopeptidase activity
IC770_17125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC770_17135	COG2813	Specifically methylates the guanine in position
IC770_17135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC770_17230	COG0788	formyltetrahydrofolate deformylase activity
IC770_17255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC770_17255	COG4651	solute:proton antiporter activity
IC770_17275	COG0724	RNA recognition motif
IC770_17280	COG0210	DNA helicase
IC770_17305	COG1733	regulation of RNA biosynthetic process
IC770_17315	COG2900	Belongs to the SlyX family
IC770_17320	COG0488	(ABC) transporter
IC770_17330	COG1280	lysine exporter protein (LysE YggA)
IC770_17335	COG1560	Kdo2-lipid A biosynthetic process
IC770_17345	COG1301	dicarboxylic acid transport
IC770_17400	COG0473	3-isopropylmalate dehydrogenase activity
IC770_17425	COG0583	DNA-binding transcription factor activity
IC770_17470	COG0583	DNA-binding transcription factor activity
IC770_17480	COG0625	glutathione transferase activity
IC770_17485	COG2378	regulation of single-species biofilm formation
IC770_17505	COG0318	PFAM AMP-dependent synthetase and ligase
IC770_17520	COG0583	DNA-binding transcription factor activity
IC770_17525	COG4221	oxidoreductase activity
IC770_17530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC770_17540	COG0534	Mate efflux family protein
IC770_17555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC770_17585	COG0493	'glutamate synthase
IC770_17585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC770_17595	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC770_17615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC770_17625	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC770_17625	COG0644	oxidoreductase
IC770_17640	COG4535	Mg2 and Co2 transporter CorC
IC770_17650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC770_17675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC770_17680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC770_17680	COG0475	glutathione-regulated potassium exporter activity
IC770_17685	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC770_17695	COG0484	heat shock protein binding
IC770_17700	COG0789	Transcriptional regulator
IC770_17705	COG0598	Magnesium transport protein CorA
IC770_17710	COG1185	polyribonucleotide nucleotidyltransferase activity
IC770_17720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC770_17725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC770_17730	COG1074	ATP-dependent DNA helicase activity
IC770_17735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC770_17760	COG2226	methyltransferase
IC770_17775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC770_17790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC770_17810	COG1006	Multisubunit Na H antiporter MnhC subunit
IC770_17815	COG0651	ATP synthesis coupled electron transport
IC770_17825	COG2212	antiporter activity
IC770_17830	COG1320	monovalent cation:proton antiporter activity
IC770_17835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC770_17845	COG0195	Participates in both transcription termination and antitermination
IC770_17895	COG0237	dephospho-CoA kinase activity
IC770_17905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC770_17915	COG0497	DNA recombination
IC770_17925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC770_17940	COG1289	transmembrane transporter activity
IC770_17955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC770_18015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC770_18030	COG0326	Molecular chaperone. Has ATPase activity
IC770_18045	COG2056	Na+-H+ antiporter family
IC770_18050	COG0596	Alpha beta hydrolase
IC770_18145	COG0546	phosphoglycolate phosphatase activity
IC770_18150	COG1716	ATPase activity
IC770_18195	COG0181	hydroxymethylbilane synthase activity
IC770_18205	COG3275	phosphorelay sensor kinase activity
IC770_18225	COG1538	Outer membrane efflux protein
IC770_18235	COG0697	spore germination
IC770_18255	COG0494	nUDIX hydrolase
IC770_18265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC770_18270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC770_18300	COG4974	Belongs to the 'phage' integrase family
IC770_18305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC770_18315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC770_18325	COG2197	response regulator
IC770_18340	COG0793	Belongs to the peptidase S41A family
IC770_18345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC770_18350	COG0795	lipopolysaccharide-transporting ATPase activity
IC770_18355	COG0795	lipopolysaccharide-transporting ATPase activity
IC770_18390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC770_18390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC770_18400	COG0004	ammonium transporteR
IC770_18405	COG0347	Belongs to the P(II) protein family
IC770_18415	COG0606	chelatase, subunit chli
IC770_18420	COG0431	NADPH-dependent FMN reductase
IC770_18425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC770_18430	COG0235	Class ii aldolase
IC770_18435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC770_18450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC770_18465	COG0318	PFAM AMP-dependent synthetase and ligase
IC770_18475	COG0477	Major facilitator Superfamily
IC770_18480	COG2860	membrane
IC770_18490	COG1253	flavin adenine dinucleotide binding
IC770_18500	COG2814	Major facilitator Superfamily
IC770_18510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC770_18545	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC770_18560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC770_18595	COG1309	transcriptional regulator
IC770_18630	COG0758	DNA mediated transformation
IC770_18640	COG0697	spore germination
IC770_18645	COG1309	transcriptional regulator
IC770_18660	COG0386	Belongs to the glutathione peroxidase family
IC770_18670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC770_18675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC770_18730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC770_18735	COG1280	lysine exporter protein (LysE YggA)
IC770_18740	COG2837	iron assimilation
IC770_18750	COG0281	malic enzyme
IC770_18785	COG0735	belongs to the Fur family
IC770_18795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC770_18800	COG0519	Catalyzes the synthesis of GMP from XMP
IC770_18800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC770_18810	COG2259	Doxx family
IC770_18815	COG0586	Pfam SNARE associated Golgi protein
IC770_18830	COG1192	Involved in chromosome partitioning
IC770_18840	COG0271	Belongs to the BolA IbaG family
IC770_18880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC770_18880	COG3321	synthase
IC770_18880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC770_18880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC770_18885	COG1960	acyl-CoA dehydrogenase activity
IC770_18895	COG2197	response regulator
IC770_18905	COG3916	Acyl-homoserine-lactone synthase
IC770_18910	COG0477	Major facilitator Superfamily
IC770_18915	COG1024	Enoyl-CoA hydratase
IC770_18920	COG1024	Enoyl-CoA hydratase
IC770_18930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC770_18950	COG1113	amino acid transport
IC770_18955	COG1113	amino acid transport
IC770_18960	COG0251	oxidation-reduction process
IC770_19000	COG0564	pseudouridine synthase activity
IC770_19070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC770_19085	COG1802	Transcriptional regulator
IC770_19100	COG0277	FAD linked oxidase domain protein
IC770_19110	COG2186	Transcriptional regulator
IC770_19120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC770_19140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC770_19145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC770_19165	COG1216	Glycosyl transferase, family 2
IC770_19165	COG0463	Glycosyl transferase, family 2
IC770_19200	COG1086	Polysaccharide biosynthesis protein
IC770_19210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC770_19215	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC770_19230	COG1596	polysaccharide export
IC770_19255	COG0728	peptidoglycan biosynthetic process
IC770_19260	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC770_19315	COG0546	phosphoglycolate phosphatase activity
IC770_19320	COG1028	Short-chain dehydrogenase reductase Sdr
IC770_19335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC770_19335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC770_19345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC770_19350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC770_19355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC770_19360	COG1116	anion transmembrane transporter activity
IC770_19365	COG1309	transcriptional regulator
IC770_19370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC770_19380	COG0196	riboflavin kinase activity
IC770_19385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC770_19395	COG1047	Peptidyl-prolyl cis-trans
IC770_19435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC770_19440	COG0657	acetylesterase activity
IC770_19490	COG2951	lytic endotransglycosylase activity
IC770_19510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC770_19520	COG0671	phosphoesterase, PA-phosphatase related
IC770_19525	COG0861	Integral membrane protein TerC family
IC770_19535	COG0754	glutathionylspermidine amidase activity
IC770_19545	COG0402	S-adenosylhomocysteine deaminase activity
IC770_19560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC770_19595	COG1979	alcohol dehydrogenase
IC770_19605	COG1902	pentaerythritol trinitrate reductase activity
IC770_19615	COG1309	transcriptional regulator
IC770_19620	COG2130	NADP-dependent
IC770_19635	COG0582	viral genome integration into host DNA
IC770_19680	COG0210	DNA helicase
IC770_19800	COG2205	protein histidine kinase activity
IC770_19815	COG2132	Multicopper oxidase
IC770_19880	COG0789	Transcriptional regulator
IC770_20040	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC770_20075	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC770_20080	COG0659	secondary active sulfate transmembrane transporter activity
IC770_20095	COG3328	transposase activity
IC770_20100	COG0583	DNA-binding transcription factor activity
IC770_20105	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC770_20110	COG3321	synthase
IC770_20110	COG0604	alcohol dehydrogenase
IC770_20120	COG0697	spore germination
IC770_20125	COG0477	Major facilitator Superfamily
IC770_20155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC770_20305	COG1525	nuclease
IC770_20365	COG1475	DNA binding
IC770_20380	COG3853	Toxic anion resistance protein (TelA)
IC770_20550	COG0741	lytic transglycosylase activity
IC770_20580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process