locus-tag	class	description
IC775_00010	COG0592	DNA-directed DNA polymerase activity
IC775_00030	COG0586	Pfam SNARE associated Golgi protein
IC775_00035	COG0488	(ABC) transporter
IC775_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC775_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC775_00110	COG1047	Peptidyl-prolyl cis-trans
IC775_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC775_00125	COG0196	riboflavin kinase activity
IC775_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC775_00140	COG1309	transcriptional regulator
IC775_00145	COG1116	anion transmembrane transporter activity
IC775_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC775_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC775_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC775_00170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC775_00170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC775_00185	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_00190	COG0546	phosphoglycolate phosphatase activity
IC775_00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC775_00250	COG0728	peptidoglycan biosynthetic process
IC775_00275	COG1596	polysaccharide export
IC775_00290	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC775_00295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC775_00305	COG1086	Polysaccharide biosynthesis protein
IC775_00340	COG0463	Glycosyl transferase, family 2
IC775_00340	COG1216	Glycosyl transferase, family 2
IC775_00345	COG0110	maltose O-acetyltransferase activity
IC775_00360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC775_00365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC775_00385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC775_00395	COG2186	Transcriptional regulator
IC775_00405	COG0277	FAD linked oxidase domain protein
IC775_00410	COG1448	Aminotransferase
IC775_00420	COG1802	Transcriptional regulator
IC775_00435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC775_00505	COG0564	pseudouridine synthase activity
IC775_00545	COG0251	oxidation-reduction process
IC775_00550	COG1113	amino acid transport
IC775_00575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC775_00580	COG1960	acyl-CoA dehydrogenase activity
IC775_00585	COG1024	Enoyl-CoA hydratase
IC775_00590	COG1024	Enoyl-CoA hydratase
IC775_00595	COG0477	Major facilitator Superfamily
IC775_00600	COG3916	Acyl-homoserine-lactone synthase
IC775_00610	COG2197	response regulator
IC775_00620	COG1960	acyl-CoA dehydrogenase activity
IC775_00625	COG3321	synthase
IC775_00625	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC775_00625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC775_00625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC775_00665	COG0271	Belongs to the BolA IbaG family
IC775_00675	COG1192	Involved in chromosome partitioning
IC775_00690	COG0586	Pfam SNARE associated Golgi protein
IC775_00695	COG2259	Doxx family
IC775_00700	COG4399	Belongs to the UPF0754 family
IC775_00710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC775_00720	COG0735	belongs to the Fur family
IC775_00755	COG0281	malic enzyme
IC775_00760	COG2826	transposase and inactivated derivatives, IS30 family
IC775_00770	COG2826	transposase and inactivated derivatives, IS30 family
IC775_00780	COG1280	lysine exporter protein (LysE YggA)
IC775_00840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC775_00845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC775_00855	COG0386	Belongs to the glutathione peroxidase family
IC775_00870	COG1309	transcriptional regulator
IC775_00875	COG0697	spore germination
IC775_00920	COG1309	transcriptional regulator
IC775_00955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC775_00970	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC775_01005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC775_01015	COG2814	Major facilitator Superfamily
IC775_01025	COG1253	flavin adenine dinucleotide binding
IC775_01035	COG2860	membrane
IC775_01040	COG0477	Major facilitator Superfamily
IC775_01050	COG0318	PFAM AMP-dependent synthetase and ligase
IC775_01065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC775_01080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC775_01085	COG0235	Class ii aldolase
IC775_01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC775_01095	COG0431	NADPH-dependent FMN reductase
IC775_01100	COG0606	chelatase, subunit chli
IC775_01110	COG0347	Belongs to the P(II) protein family
IC775_01115	COG0004	ammonium transporteR
IC775_01125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC775_01125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC775_01160	COG0795	lipopolysaccharide-transporting ATPase activity
IC775_01165	COG0795	lipopolysaccharide-transporting ATPase activity
IC775_01170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC775_01175	COG0793	Belongs to the peptidase S41A family
IC775_01190	COG2197	response regulator
IC775_01200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC775_01210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC775_01215	COG4974	Belongs to the 'phage' integrase family
IC775_01245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC775_01250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC775_01260	COG0494	nUDIX hydrolase
IC775_01280	COG0697	spore germination
IC775_01290	COG1538	Outer membrane efflux protein
IC775_01320	COG0181	hydroxymethylbilane synthase activity
IC775_01365	COG1716	ATPase activity
IC775_01370	COG0546	phosphoglycolate phosphatase activity
IC775_01465	COG0596	Alpha beta hydrolase
IC775_01470	COG2056	Na+-H+ antiporter family
IC775_01485	COG0326	Molecular chaperone. Has ATPase activity
IC775_01500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC775_01560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC775_01575	COG1289	transmembrane transporter activity
IC775_01590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC775_01600	COG0497	DNA recombination
IC775_01610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC775_01620	COG0237	dephospho-CoA kinase activity
IC775_01670	COG0195	Participates in both transcription termination and antitermination
IC775_01680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC775_01685	COG1320	monovalent cation:proton antiporter activity
IC775_01690	COG2212	antiporter activity
IC775_01695	COG1863	multisubunit Na H antiporter MnhE subunit
IC775_01700	COG0651	ATP synthesis coupled electron transport
IC775_01705	COG1006	Multisubunit Na H antiporter MnhC subunit
IC775_01710	COG2111	Na H antiporter
IC775_01710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC775_01725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC775_01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC775_01755	COG2226	methyltransferase
IC775_01780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC775_01785	COG1074	ATP-dependent DNA helicase activity
IC775_01790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC775_01795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC775_01805	COG1185	polyribonucleotide nucleotidyltransferase activity
IC775_01810	COG0598	Magnesium transport protein CorA
IC775_01815	COG0789	Transcriptional regulator
IC775_01830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC775_01835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC775_01835	COG0475	glutathione-regulated potassium exporter activity
IC775_01840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC775_01865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC775_01875	COG4535	Mg2 and Co2 transporter CorC
IC775_01890	COG0644	oxidoreductase
IC775_01890	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC775_01900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC775_01920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC775_01930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC775_01930	COG0493	'glutamate synthase
IC775_01960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC775_01975	COG0534	Mate efflux family protein
IC775_01985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC775_01990	COG4221	oxidoreductase activity
IC775_01995	COG0583	DNA-binding transcription factor activity
IC775_02015	COG1530	ribonuclease E activity
IC775_02030	COG2378	regulation of single-species biofilm formation
IC775_02035	COG0625	glutathione transferase activity
IC775_02045	COG0583	DNA-binding transcription factor activity
IC775_02090	COG0583	DNA-binding transcription factor activity
IC775_02115	COG0473	3-isopropylmalate dehydrogenase activity
IC775_02180	COG1560	Kdo2-lipid A biosynthetic process
IC775_02185	COG1280	lysine exporter protein (LysE YggA)
IC775_02195	COG0488	(ABC) transporter
IC775_02200	COG2900	Belongs to the SlyX family
IC775_02210	COG1733	regulation of RNA biosynthetic process
IC775_02235	COG0210	DNA helicase
IC775_02240	COG0724	RNA recognition motif
IC775_02285	COG0788	formyltetrahydrofolate deformylase activity
IC775_02390	COG2813	Specifically methylates the guanine in position
IC775_02390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC775_02410	COG4774	siderophore transport
IC775_02420	COG0740	serine-type endopeptidase activity
IC775_02440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC775_02440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC775_02445	COG0280	phosphate acetyltransferase
IC775_02445	COG0857	belongs to the CobB CobQ family
IC775_02450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC775_02460	COG0800	Aldolase
IC775_02470	COG3265	gluconokinase activity
IC775_02475	COG1012	belongs to the aldehyde dehydrogenase family
IC775_02485	COG2267	carboxylic ester hydrolase activity
IC775_02500	COG0793	Belongs to the peptidase S41A family
IC775_02535	COG1426	Protein conserved in bacteria
IC775_02575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC775_02585	COG1162	GTPase activity
IC775_02590	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC775_02605	COG1538	Outer membrane efflux protein
IC775_02610	COG1136	(ABC) transporter
IC775_02610	COG0577	efflux transmembrane transporter activity
IC775_02640	COG0028	Belongs to the TPP enzyme family
IC775_02645	COG0440	acetolactate synthase activity
IC775_02650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC775_02685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC775_02700	COG0084	hydrolase, TatD family'
IC775_02710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC775_02720	COG0583	DNA-binding transcription factor activity
IC775_02730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC775_02845	COG2814	Major facilitator Superfamily
IC775_02860	COG1230	cation diffusion facilitator family transporter
IC775_02885	COG2814	Major facilitator Superfamily
IC775_02930	COG3622	Belongs to the hyi family
IC775_02935	COG2084	Dehydrogenase
IC775_02940	COG1024	Enoyl-CoA hydratase
IC775_02945	COG5002	protein histidine kinase activity
IC775_02945	COG0784	Response regulator, receiver
IC775_02945	COG2205	protein histidine kinase activity
IC775_02965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC775_02975	COG3956	TIGRFAM MazG family protein
IC775_02980	COG1555	photosystem II stabilization
IC775_02985	COG0617	tRNA 3'-terminal CCA addition
IC775_02990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC775_03015	COG3028	Belongs to the UPF0307 family
IC775_03020	COG0318	PFAM AMP-dependent synthetase and ligase
IC775_03035	COG0625	glutathione transferase activity
IC775_03040	COG1238	metal cluster binding
IC775_03050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC775_03110	COG0248	Ppx GppA phosphatase
IC775_03120	COG0037	tRNA processing
IC775_03160	COG1764	response to oxidative stress
IC775_03165	COG1846	Transcriptional regulator
IC775_03175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC775_03235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC775_03240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC775_03245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC775_03255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC775_03305	COG1214	PFAM Peptidase M22, glycoprotease
IC775_03320	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC775_03330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC775_03335	COG0561	phosphatase activity
IC775_03370	COG2826	transposase and inactivated derivatives, IS30 family
IC775_03380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC775_03385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC775_03415	COG1063	alcohol dehydrogenase
IC775_03425	COG1960	acyl-CoA dehydrogenase activity
IC775_03430	COG2814	Major facilitator Superfamily
IC775_03435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC775_03445	COG1309	transcriptional regulator
IC775_03460	COG1053	succinate dehydrogenase
IC775_03480	COG0583	DNA-binding transcription factor activity
IC775_03490	COG0583	DNA-binding transcription factor activity
IC775_03505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC775_03550	COG0583	DNA-binding transcription factor activity
IC775_03555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC775_03585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC775_03605	COG0745	RESPONSE REGULATOR receiver
IC775_03620	COG3706	GGDEF domain
IC775_03645	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC775_03660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC775_03675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC775_03680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC775_03705	COG0583	DNA-binding transcription factor activity
IC775_03725	COG0668	transmembrane transport
IC775_03735	COG2081	HI0933 family
IC775_03740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC775_03775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC775_03775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC775_03785	COG0489	protein tyrosine kinase activity
IC775_03790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC775_03835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC775_03845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC775_03860	COG0730	response to heat
IC775_03870	COG1196	nuclear chromosome segregation
IC775_03890	COG2223	nitrite transmembrane transporter activity
IC775_03895	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC775_03905	COG0596	Alpha beta hydrolase
IC775_03905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC775_03905	COG2226	methyltransferase
IC775_03920	COG4106	trans-aconitate 2-methyltransferase activity
IC775_03935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC775_03940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC775_03950	COG3101	peptidyl-lysine hydroxylation
IC775_03955	COG1399	metal-binding, possibly nucleic acid-binding protein
IC775_03980	COG1652	LysM domain
IC775_03985	COG0351	phosphomethylpyrimidine kinase
IC775_03985	COG0352	thiamine-phosphate diphosphorylase activity
IC775_03985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC775_03995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC775_04025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC775_04055	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC775_04070	COG0358	DNA primase activity
IC775_04080	COG0564	pseudouridine synthase activity
IC775_04105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC775_04125	COG0583	DNA-binding transcription factor activity
IC775_04140	COG0657	acetylesterase activity
IC775_04145	COG4638	Rieske (2fe-2S)
IC775_04150	COG1012	belongs to the aldehyde dehydrogenase family
IC775_04170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC775_04170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC775_04180	COG1981	membrane
IC775_04195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC775_04205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC775_04225	COG0456	acetyltransferase
IC775_04235	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC775_04240	COG0492	ferredoxin-NADP+ reductase activity
IC775_04245	COG1674	ftsk spoiiie
IC775_04250	COG1280	lysine exporter protein (LysE YggA)
IC775_04265	COG2894	cell division
IC775_04280	COG0204	Acyl-transferase
IC775_04285	COG2885	chlorophyll binding
IC775_04290	COG0210	DNA helicase
IC775_04315	COG0121	glutamine amidotransferase
IC775_04330	COG2914	Belongs to the UPF0125 (RnfH) family
IC775_04335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC775_04340	COG0735	belongs to the Fur family
IC775_04360	COG1968	undecaprenyl-diphosphatase activity
IC775_04370	COG0420	3'-5' exonuclease activity
IC775_04390	COG1090	epimerase
IC775_04405	COG2050	protein possibly involved in aromatic compounds catabolism
IC775_04415	COG2814	Major facilitator Superfamily
IC775_04420	COG0405	Gamma-glutamyltransferase
IC775_04480	COG3586	endonuclease activity
IC775_04530	COG0477	Major facilitator Superfamily
IC775_04535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC775_04555	COG0531	amino acid
IC775_04560	COG2040	homocysteine
IC775_04590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC775_04595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC775_04605	COG1607	acyl-coa hydrolase
IC775_04615	COG0523	cobalamin synthesis protein
IC775_04625	COG4681	YaeQ
IC775_04635	COG0726	polysaccharide deacetylase
IC775_04635	COG1649	PFAM Uncharacterised BCR, COG1649
IC775_04640	COG1215	transferase activity, transferring glycosyl groups
IC775_04650	COG1024	Enoyl-CoA hydratase
IC775_04680	COG1414	Transcriptional regulator
IC775_04715	COG2271	Major facilitator Superfamily
IC775_04725	COG2267	carboxylic ester hydrolase activity
IC775_04730	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_04745	COG0028	Belongs to the TPP enzyme family
IC775_04760	COG0242	peptide deformylase activity
IC775_04765	COG2066	Belongs to the glutaminase family
IC775_04770	COG2207	Transcriptional regulator
IC775_04775	COG2223	nitrite transmembrane transporter activity
IC775_04805	COG0306	phosphate transporter
IC775_04825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC775_04870	COG4181	ATPase activity
IC775_04900	COG0583	DNA-binding transcription factor activity
IC775_04910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC775_04915	COG1773	rubredoxin
IC775_04965	COG2851	Citrate transporter
IC775_04970	COG1253	flavin adenine dinucleotide binding
IC775_05010	COG0804	urea catabolic process
IC775_05020	COG0830	nickel cation binding
IC775_05040	COG0742	ribosomal rna small subunit methyltransferase
IC775_05045	COG0768	penicillin binding
IC775_05070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC775_05075	COG2878	Part of a membrane complex involved in electron transport
IC775_05080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC775_05090	COG3384	dioxygenase
IC775_05135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC775_05165	COG1674	ftsk spoiiie
IC775_05490	COG0006	proline dipeptidase activity
IC775_05495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC775_05500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC775_05525	COG0583	DNA-binding transcription factor activity
IC775_05570	COG1388	LysM domain
IC775_05570	COG0741	lytic transglycosylase activity
IC775_05580	COG4174	ABC transporter (Permease)
IC775_05585	COG4239	(ABC) transporter, permease
IC775_05590	COG4172	Belongs to the ABC transporter superfamily
IC775_05615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC775_05625	COG2203	Gaf domain
IC775_05625	COG3706	GGDEF domain
IC775_05625	COG4251	negative regulation of phosphorylation
IC775_05625	COG5001	Diguanylate cyclase
IC775_05635	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC775_05635	COG1902	pentaerythritol trinitrate reductase activity
IC775_05650	COG0251	oxidation-reduction process
IC775_05660	COG0583	DNA-binding transcription factor activity
IC775_05680	COG4269	membrane
IC775_05775	COG1113	amino acid transport
IC775_05785	COG0531	amino acid
IC775_05805	COG1012	belongs to the aldehyde dehydrogenase family
IC775_05845	COG0697	spore germination
IC775_05865	COG1960	acyl-CoA dehydrogenase activity
IC775_05875	COG1012	belongs to the aldehyde dehydrogenase family
IC775_05880	COG1024	Enoyl-CoA hydratase
IC775_05885	COG2814	Major facilitator Superfamily
IC775_05900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC775_05920	COG1944	ATP diphosphatase activity
IC775_05950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC775_05965	COG0583	DNA-binding transcription factor activity
IC775_05970	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC775_05975	COG2072	flavoprotein involved in K transport
IC775_05990	COG1309	transcriptional regulator
IC775_05995	COG1741	Belongs to the pirin family
IC775_06010	COG2072	flavoprotein involved in K transport
IC775_06020	COG2252	PERMEase
IC775_06025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC775_06030	COG3038	cytochrome b561
IC775_06040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC775_06050	COG0527	aspartate kinase activity
IC775_06060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC775_06075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC775_06090	COG0667	Aldo Keto reductase
IC775_06100	COG1765	OsmC-like protein
IC775_06115	COG0542	response to heat
IC775_06160	COG0625	glutathione transferase activity
IC775_06165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC775_06185	COG3634	alkyl hydroperoxide reductase activity
IC775_06205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC775_06220	COG1643	Atp-dependent helicase
IC775_06240	COG2814	Major facilitator Superfamily
IC775_06245	COG3135	benzoate transporter
IC775_06250	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_06255	COG0633	Ferredoxin
IC775_06255	COG0543	2 iron, 2 sulfur cluster binding
IC775_06260	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC775_06265	COG4638	Rieske (2fe-2S)
IC775_06275	COG0583	DNA-binding transcription factor activity
IC775_06285	COG2871	sodium ion transport
IC775_06370	COG1570	exodeoxyribonuclease VII activity
IC775_06405	COG1280	lysine exporter protein (LysE YggA)
IC775_06410	COG1278	Cold shock
IC775_06440	COG2814	Major facilitator Superfamily
IC775_06450	COG0667	Aldo Keto reductase
IC775_06470	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC775_06470	COG0517	IMP dehydrogenase activity
IC775_06475	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC775_06485	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC775_06490	COG1137	ATPase activity
IC775_06495	COG1538	Outer membrane efflux protein
IC775_06525	COG4122	O-methyltransferase activity
IC775_06535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC775_06600	COG1469	GTP cyclohydrolase I activity
IC775_06605	COG1294	oxidase, subunit
IC775_06610	COG1271	oxidase subunit
IC775_06620	COG0583	DNA-binding transcription factor activity
IC775_06625	COG0402	S-adenosylhomocysteine deaminase activity
IC775_06640	COG2814	Major facilitator Superfamily
IC775_06660	COG4774	siderophore transport
IC775_06665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC775_06675	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_06685	COG1522	sequence-specific DNA binding
IC775_06700	COG1278	Cold shock
IC775_06705	COG1309	transcriptional regulator
IC775_06790	COG3209	COG3209 Rhs family protein
IC775_06835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC775_06840	COG3713	MltA-interacting MipA family protein
IC775_06855	COG2076	Multidrug Resistance protein
IC775_06870	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_06885	COG3220	belongs to the UPF0276 family
IC775_06895	COG1595	DNA-templated transcription, initiation
IC775_06910	COG1914	H( )-stimulated, divalent metal cation uptake system
IC775_06930	COG4770	biotin carboxylase activity
IC775_06935	COG0038	chloride channel
IC775_06980	COG1063	alcohol dehydrogenase
IC775_06995	COG0439	Biotin carboxylase
IC775_07000	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC775_07005	COG1733	regulation of RNA biosynthetic process
IC775_07020	COG0864	Transcriptional regulator
IC775_07030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC775_07035	COG1116	anion transmembrane transporter activity
IC775_07060	COG0477	Major facilitator Superfamily
IC775_07165	COG0590	tRNA wobble adenosine to inosine editing
IC775_07170	COG2807	transmembrane transport
IC775_07185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC775_07190	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC775_07200	COG0789	Transcriptional regulator
IC775_07210	COG1760	l-serine dehydratase
IC775_07220	COG3396	Phenylacetate-CoA oxygenase
IC775_07225	COG3460	Phenylacetate-CoA oxygenase
IC775_07230	COG3396	Phenylacetate-CoA oxygenase
IC775_07235	COG2151	metal-sulfur cluster biosynthetic enzyme
IC775_07245	COG1024	Enoyl-CoA hydratase
IC775_07250	COG1024	Enoyl-CoA hydratase
IC775_07265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC775_07270	COG3327	negative regulation of DNA-templated transcription, initiation
IC775_07280	COG2050	protein possibly involved in aromatic compounds catabolism
IC775_07290	COG0406	alpha-ribazole phosphatase activity
IC775_07310	COG3179	chitinase
IC775_07365	COG1309	transcriptional regulator
IC775_07370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC775_07385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC775_07390	COG0531	amino acid
IC775_07395	COG0753	catalase activity
IC775_07400	COG3038	cytochrome b561
IC775_07415	COG0583	DNA-binding transcription factor activity
IC775_07425	COG1414	Transcriptional regulator
IC775_07430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC775_07445	COG1840	ABC-type Fe3 transport system, periplasmic component
IC775_07465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC775_07470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC775_07475	COG2814	Major facilitator Superfamily
IC775_07480	COG1960	acyl-CoA dehydrogenase activity
IC775_07485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC775_07495	COG1024	Enoyl-CoA hydratase
IC775_07510	COG2814	Major facilitator Superfamily
IC775_07520	COG0183	Belongs to the thiolase family
IC775_07525	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC775_07535	COG1024	Enoyl-CoA hydratase
IC775_07540	COG1960	acyl-CoA dehydrogenase activity
IC775_07565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC775_07575	COG2814	Major facilitator Superfamily
IC775_07585	COG1960	acyl-CoA dehydrogenase activity
IC775_07600	COG0583	DNA-binding transcription factor activity
IC775_07610	COG4770	biotin carboxylase activity
IC775_07615	COG1024	Enoyl-CoA hydratase
IC775_07620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC775_07625	COG1960	acyl-CoA dehydrogenase activity
IC775_07630	COG1309	transcriptional regulator
IC775_07635	COG0318	PFAM AMP-dependent synthetase and ligase
IC775_07655	COG0583	DNA-binding transcription factor activity
IC775_07700	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_07720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC775_07740	COG2205	protein histidine kinase activity
IC775_07740	COG0784	Response regulator, receiver
IC775_07780	COG0765	amino acid transport
IC775_07785	COG0765	amino acid transport
IC775_07795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC775_07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC775_07810	COG1280	lysine exporter protein (LysE YggA)
IC775_07815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC775_07825	COG1045	serine acetyltransferase
IC775_07840	COG0583	DNA-binding transcription factor activity
IC775_07845	COG0625	glutathione transferase activity
IC775_07855	COG0583	DNA-binding transcription factor activity
IC775_07865	COG1346	cytolysis
IC775_07890	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC775_07895	COG3052	prosthetic group binding
IC775_07915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC775_07935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC775_07945	COG1294	oxidase, subunit
IC775_07950	COG1271	oxidase subunit
IC775_07970	COG0477	Major facilitator Superfamily
IC775_07980	COG4521	taurine ABC transporter
IC775_07985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC775_07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC775_07995	COG2175	clavaminate synthase activity
IC775_08005	COG1953	Uracil, thiamine, allantoin
IC775_08015	COG0583	DNA-binding transcription factor activity
IC775_08025	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC775_08040	COG0640	Transcriptional regulator
IC775_08045	COG0798	PFAM Bile acid sodium symporter
IC775_08050	COG0431	NADPH-dependent FMN reductase
IC775_08055	COG0583	DNA-binding transcription factor activity
IC775_08070	COG3634	alkyl hydroperoxide reductase activity
IC775_08105	COG1301	dicarboxylic acid transport
IC775_08110	COG0436	Aminotransferase
IC775_08120	COG0386	Belongs to the glutathione peroxidase family
IC775_08125	COG2207	Transcriptional regulator
IC775_08125	COG1917	Cupin 2, conserved barrel domain protein
IC775_08160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC775_08185	COG0012	GTP binding
IC775_08190	COG2011	ABC-type metal ion transport system permease component
IC775_08195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC775_08205	COG1464	Belongs to the NlpA lipoprotein family
IC775_08235	COG0765	amino acid transport
IC775_08240	COG0765	amino acid transport
IC775_08245	COG1126	abc transporter atp-binding protein
IC775_08255	COG1522	sequence-specific DNA binding
IC775_08280	COG2197	response regulator
IC775_08300	COG0583	DNA-binding transcription factor activity
IC775_08310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC775_08320	COG0697	spore germination
IC775_08340	COG3121	Chaperone
IC775_08345	COG3539	Fimbrial protein
IC775_08370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC775_08370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC775_08410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC775_08425	COG2353	YceI-like domain
IC775_08450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC775_08455	COG0506	proline dehydrogenase activity
IC775_08455	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC775_08455	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC775_08465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC775_08470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC775_08490	COG1132	(ABC) transporter
IC775_08495	COG3122	Protein conserved in bacteria
IC775_08500	COG3619	membrane
IC775_08520	COG2850	peptidyl-arginine hydroxylation
IC775_08525	COG0424	maF-like protein
IC775_08565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC775_08575	COG1192	Involved in chromosome partitioning
IC775_08580	COG1475	DNA binding
IC775_08585	COG0811	peptide transport
IC775_08595	COG1132	(ABC) transporter
IC775_08600	COG1663	tetraacyldisaccharide 4'-kinase activity
IC775_08620	COG0084	hydrolase, TatD family'
IC775_08685	COG0776	regulation of translation
IC775_08700	COG2431	L-lysine efflux transmembrane transporter activity
IC775_08715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC775_08760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC775_08775	COG0305	Participates in initiation and elongation during chromosome replication
IC775_08855	COG4695	Portal protein
IC775_08975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC775_09000	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC775_09025	COG0601	transmembrane transport
IC775_09030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC775_09035	COG4172	Belongs to the ABC transporter superfamily
IC775_09065	COG0702	epimerase
IC775_09070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC775_09090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC775_09120	COG0316	Belongs to the HesB IscA family
IC775_09125	COG0822	iron-sulfur transferase activity
IC775_09150	COG0776	regulation of translation
IC775_09160	COG2207	Transcriptional regulator
IC775_09165	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC775_09170	COG1960	acyl-CoA dehydrogenase activity
IC775_09175	COG1960	acyl-CoA dehydrogenase activity
IC775_09210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC775_09215	COG0406	alpha-ribazole phosphatase activity
IC775_09230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC775_09235	COG0730	response to heat
IC775_09255	COG4773	Receptor
IC775_09260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC775_09275	COG1131	(ABC) transporter
IC775_09280	COG0842	Transport permease protein
IC775_09285	COG0842	Transport permease protein
IC775_09330	COG2826	transposase and inactivated derivatives, IS30 family
IC775_09340	COG2226	methyltransferase
IC775_09365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC775_09400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC775_09425	COG3706	GGDEF domain
IC775_09440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC775_09445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC775_09450	COG0022	dehydrogenase e1 component
IC775_09455	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC775_09460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC775_09470	COG1063	alcohol dehydrogenase
IC775_09475	COG3781	membrane
IC775_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC775_09485	COG3453	Protein conserved in bacteria
IC775_09495	COG0730	response to heat
IC775_09510	COG2207	Transcriptional regulator
IC775_09510	COG3708	Transcriptional regulator
IC775_09520	COG0477	Major facilitator Superfamily
IC775_09530	COG1027	Aspartate ammonia-lyase
IC775_09545	COG0583	DNA-binding transcription factor activity
IC775_09550	COG0583	DNA-binding transcription factor activity
IC775_09555	COG0183	Belongs to the thiolase family
IC775_09560	COG2031	fatty acid transporter
IC775_09575	COG0583	DNA-binding transcription factor activity
IC775_09600	COG2814	Major facilitator Superfamily
IC775_09630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC775_09640	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_09645	COG2207	Transcriptional regulator
IC775_09665	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_09675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC775_09690	COG0543	2 iron, 2 sulfur cluster binding
IC775_09690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC775_09695	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC775_09700	COG4638	Rieske (2fe-2S)
IC775_09710	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC775_09715	COG4149	molybdate abc transporter
IC775_09720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC775_09745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC775_09750	COG3251	PFAM MbtH domain protein
IC775_09760	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_09765	COG1169	isochorismate synthase
IC775_09775	COG3433	isochorismatase activity
IC775_09775	COG1535	isochorismatase
IC775_09785	COG4771	TonB-dependent receptor
IC775_09845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC775_09850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_09855	COG0745	RESPONSE REGULATOR receiver
IC775_09860	COG2205	protein histidine kinase activity
IC775_09870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC775_09875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC775_09885	COG0753	catalase activity
IC775_09895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC775_09920	COG3539	Fimbrial protein
IC775_09950	COG0601	transmembrane transport
IC775_09955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC775_09980	COG1132	(ABC) transporter
IC775_10000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC775_10010	COG0805	protein transport
IC775_10015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC775_10030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC775_10035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC775_10040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC775_10045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC775_10075	COG4771	TonB-dependent receptor
IC775_10080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC775_10085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC775_10115	COG2175	clavaminate synthase activity
IC775_10135	COG0667	Aldo Keto reductase
IC775_10150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC775_10275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC775_10295	COG1120	ATPase activity
IC775_10300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC775_10330	COG1566	PFAM secretion protein HlyD family protein
IC775_10340	COG2271	Major facilitator Superfamily
IC775_10355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC775_10370	COG2188	Transcriptional regulator
IC775_10450	COG1309	transcriptional regulator
IC775_10475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC775_10505	COG0583	DNA-binding transcription factor activity
IC775_10510	COG4948	Mandelate Racemase Muconate Lactonizing
IC775_10515	COG4829	muconolactone delta-isomerase
IC775_10525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC775_10530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC775_10535	COG0183	Belongs to the thiolase family
IC775_10540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC775_10545	COG1012	belongs to the aldehyde dehydrogenase family
IC775_10560	COG3733	amine oxidase
IC775_10570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC775_10580	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_10590	COG4638	Rieske (2fe-2S)
IC775_10610	COG0154	amidase activity
IC775_10620	COG2814	Major facilitator Superfamily
IC775_10645	COG1960	acyl-CoA dehydrogenase activity
IC775_10650	COG0583	DNA-binding transcription factor activity
IC775_10655	COG1414	Transcriptional regulator
IC775_10670	COG2391	methyltransferase activity
IC775_10680	COG4993	Dehydrogenase
IC775_10690	COG3420	alginic acid biosynthetic process
IC775_10700	COG3485	protocatechuate 3,4-dioxygenase
IC775_10705	COG3485	protocatechuate 3,4-dioxygenase
IC775_10710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC775_10715	COG2271	Major facilitator Superfamily
IC775_10720	COG0596	Alpha beta hydrolase
IC775_10725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC775_10735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC775_10740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC775_10750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC775_10760	COG2323	membrane
IC775_10765	COG0148	phosphopyruvate hydratase activity
IC775_10805	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC775_10805	COG1902	pentaerythritol trinitrate reductase activity
IC775_10830	COG0542	response to heat
IC775_10835	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC775_10865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC775_10870	COG0569	domain protein
IC775_10875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC775_10890	COG4774	siderophore transport
IC775_10895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC775_10905	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC775_10920	COG1294	oxidase, subunit
IC775_10925	COG4890	Cyd operon protein YbgT
IC775_10950	COG0552	protein localization to endoplasmic reticulum
IC775_10975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC775_10980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC775_10985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC775_10995	COG0583	DNA-binding transcription factor activity
IC775_11000	COG0024	Methionine aminopeptidase
IC775_11030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC775_11030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC775_11035	COG1105	Belongs to the carbohydrate kinase PfkB family
IC775_11040	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC775_11040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC775_11040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC775_11075	COG0659	secondary active sulfate transmembrane transporter activity
IC775_11090	COG1113	amino acid transport
IC775_11100	COG1522	sequence-specific DNA binding
IC775_11115	COG1011	Hydrolase
IC775_11130	COG2137	regulation of response to DNA damage stimulus
IC775_11145	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC775_11165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC775_11180	COG0575	Belongs to the CDS family
IC775_11185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC775_11210	COG3852	Histidine kinase
IC775_11215	COG2204	response regulator
IC775_11270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC775_11275	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC775_11300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC775_11310	COG0303	'Molybdopterin
IC775_11330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC775_11335	COG0243	molybdopterin cofactor binding
IC775_11345	COG0243	molybdopterin cofactor binding
IC775_11350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC775_11355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC775_11355	COG2146	nitrite reductase [NAD(P)H] activity
IC775_11365	COG0745	RESPONSE REGULATOR receiver
IC775_11370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC775_11370	COG1116	anion transmembrane transporter activity
IC775_11390	COG0511	ligase activity, forming carbon-carbon bonds
IC775_11405	COG2814	Major facilitator Superfamily
IC775_11450	COG0069	glutamate synthase activity
IC775_11480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC775_11495	COG1335	isochorismatase
IC775_11505	COG1454	alcohol dehydrogenase
IC775_11510	COG0824	Thioesterase
IC775_11525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC775_11550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC775_11555	COG2030	dehydratase
IC775_11560	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_11575	COG0583	DNA-binding transcription factor activity
IC775_11580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC775_11590	COG1522	sequence-specific DNA binding
IC775_11595	COG3135	benzoate transporter
IC775_11620	COG0589	response to stress
IC775_11625	COG0488	(ABC) transporter
IC775_11670	COG0668	transmembrane transport
IC775_11690	COG4264	IucA IucC family
IC775_11700	COG4264	IucA IucC family
IC775_11745	COG1605	Chorismate mutase
IC775_11760	COG0625	glutathione transferase activity
IC775_11790	COG0308	aminopeptidase N
IC775_11810	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC775_11820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC775_11845	COG0531	amino acid
IC775_11850	COG4303	Ethanolamine ammonia lyase large subunit
IC775_11855	COG4302	ethanolamine ammonia-lyase activity
IC775_11860	COG0519	Catalyzes the synthesis of GMP from XMP
IC775_11860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC775_11865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC775_11895	COG1923	regulation of RNA biosynthetic process
IC775_11905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC775_11910	COG0802	atpase or kinase
IC775_11930	COG1187	pseudouridine synthase activity
IC775_11945	COG0583	DNA-binding transcription factor activity
IC775_11955	COG2814	Major facilitator Superfamily
IC775_11990	COG0729	surface antigen
IC775_12010	COG0174	glutamine synthetase
IC775_12015	COG0745	RESPONSE REGULATOR receiver
IC775_12020	COG2205	protein histidine kinase activity
IC775_12025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC775_12030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC775_12035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC775_12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC775_12065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC775_12070	COG1960	acyl-CoA dehydrogenase activity
IC775_12085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC775_12090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC775_12095	COG2890	protein-(glutamine-N5) methyltransferase activity
IC775_12115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC775_12125	COG3658	cytochrome
IC775_12130	COG1215	transferase activity, transferring glycosyl groups
IC775_12135	COG0726	polysaccharide deacetylase
IC775_12135	COG1649	PFAM Uncharacterised BCR, COG1649
IC775_12165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC775_12175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC775_12200	COG0305	Participates in initiation and elongation during chromosome replication
IC775_12205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC775_12215	COG1305	Transglutaminase-like
IC775_12225	COG2308	Evidence 4 Homologs of previously reported genes of
IC775_12255	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC775_12260	COG0138	bifunctional purine biosynthesis protein purh
IC775_12265	COG0151	Belongs to the GarS family
IC775_12270	COG1464	Belongs to the NlpA lipoprotein family
IC775_12275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC775_12280	COG2011	ABC-type metal ion transport system permease component
IC775_12295	COG1301	dicarboxylic acid transport
IC775_12340	COG2855	membrane
IC775_12355	COG2814	Major facilitator Superfamily
IC775_12360	COG3246	L-lysine catabolic process to acetate
IC775_12365	COG2175	clavaminate synthase activity
IC775_12390	COG0745	RESPONSE REGULATOR receiver
IC775_12395	COG0642	Histidine kinase
IC775_12400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC775_12435	COG5002	protein histidine kinase activity
IC775_12450	COG2351	hydroxyisourate hydrolase activity
IC775_12460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC775_12460	COG3008	intermembrane lipid transfer
IC775_12465	COG2995	paraquat-inducible protein a
IC775_12490	COG2985	domain, Protein
IC775_12505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC775_12505	COG2169	Transcriptional regulator
IC775_12515	COG1309	transcriptional regulator
IC775_12600	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_12605	COG0475	glutathione-regulated potassium exporter activity
IC775_12605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC775_12610	COG0786	glutamate:sodium symporter activity
IC775_12620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC775_12630	COG0596	Alpha beta hydrolase
IC775_12650	COG0583	DNA-binding transcription factor activity
IC775_12655	COG1335	isochorismatase
IC775_12760	COG0515	serine threonine protein kinase
IC775_12760	COG2815	serine threonine protein kinase
IC775_12790	COG1610	YqeY-like protein
IC775_12850	COG0778	Nitroreductase
IC775_12860	COG0513	Belongs to the DEAD box helicase family
IC775_12880	COG2363	Small membrane protein
IC775_12905	COG4650	regulator
IC775_12910	COG1234	tRNA 3'-trailer cleavage
IC775_12915	COG1690	Belongs to the RtcB family
IC775_12935	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC775_12940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC775_12950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC775_12970	COG1960	acyl-CoA dehydrogenase activity
IC775_12975	COG1301	dicarboxylic acid transport
IC775_12985	COG3139	Protein of unknown function (DUF1315)
IC775_12990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC775_12995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC775_13005	COG0494	nUDIX hydrolase
IC775_13015	COG0642	Histidine kinase
IC775_13040	COG1720	tRNA m6t6A37 methyltransferase activity
IC775_13050	COG0384	phenazine biosynthesis protein PhzF
IC775_13055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC775_13060	COG0826	peptidase U32
IC775_13065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC775_13075	COG4598	ABC transporter
IC775_13080	COG4160	amino acid transport
IC775_13085	COG4215	(ABC) transporter
IC775_13100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_13140	COG1131	(ABC) transporter
IC775_13145	COG0842	Transport permease protein
IC775_13165	COG2951	lytic endotransglycosylase activity
IC775_13210	COG0024	Methionine aminopeptidase
IC775_13230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC775_13235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC775_13260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC775_13285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC775_13290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC775_13295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC775_13340	COG0174	glutamine synthetase
IC775_13355	COG0512	Glutamine amidotransferase of anthranilate synthase
IC775_13370	COG2840	Smr protein MutS2
IC775_13380	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC775_13390	COG0302	gtp cyclohydrolase
IC775_13410	COG3739	integral membrane protein
IC775_13425	COG1741	Belongs to the pirin family
IC775_13435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC775_13455	COG2964	Protein conserved in bacteria
IC775_13465	COG2423	ornithine cyclodeaminase activity
IC775_13470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC775_13510	COG2814	Major facilitator Superfamily
IC775_13540	COG2879	small protein
IC775_13545	COG1966	Carbon starvation protein
IC775_13550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC775_13565	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC775_13590	COG1067	ATP-dependent peptidase activity
IC775_13595	COG0583	DNA-binding transcription factor activity
IC775_13620	COG1686	Belongs to the peptidase S11 family
IC775_13625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC775_13650	COG3647	Membrane
IC775_13670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC775_13680	COG0573	inorganic phosphate transmembrane transporter activity
IC775_13685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC775_13690	COG1113	amino acid transport
IC775_13695	COG3961	Belongs to the TPP enzyme family
IC775_13700	COG1522	sequence-specific DNA binding
IC775_13710	COG0076	glutamate decarboxylase activity
IC775_13715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC775_13740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC775_13775	COG0352	thiamine-phosphate diphosphorylase activity
IC775_13810	COG0612	Peptidase, M16
IC775_13820	COG1823	symporter activity
IC775_13825	COG0583	DNA-binding transcription factor activity
IC775_13830	COG0477	Major facilitator Superfamily
IC775_13905	COG0741	lytic transglycosylase activity
IC775_13905	COG0739	heme binding
IC775_13905	COG1196	nuclear chromosome segregation
IC775_14015	COG3728	DNA packaging
IC775_14015	COG5484	DNA packaging
IC775_14210	COG1187	pseudouridine synthase activity
IC775_14230	COG1252	NADH dehydrogenase
IC775_14240	COG0415	Belongs to the DNA photolyase family
IC775_14255	COG1215	transferase activity, transferring glycosyl groups
IC775_14270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC775_14285	COG2070	2-Nitropropane dioxygenase
IC775_14340	COG0556	nucleotide-excision repair
IC775_14345	COG3706	GGDEF domain
IC775_14365	COG0436	Aminotransferase
IC775_14390	COG4221	oxidoreductase activity
IC775_14400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC775_14405	COG1381	Involved in DNA repair and RecF pathway recombination
IC775_14415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC775_14430	COG0681	Belongs to the peptidase S26 family
IC775_14445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC775_14465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC775_14475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC775_14485	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC775_14490	COG4208	sulfate ABC transporter
IC775_14495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC775_14500	COG0583	DNA-binding transcription factor activity
IC775_14505	COG4625	pathogenesis
IC775_14515	COG0602	queuosine metabolic process
IC775_14520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC775_14535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC775_14550	COG1056	cytidyltransferase-related domain
IC775_14550	COG1051	belongs to the nudix hydrolase family
IC775_14555	COG1024	Enoyl-CoA hydratase
IC775_14560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC775_14575	COG2814	Major facilitator Superfamily
IC775_14580	COG0047	phosphoribosylformylglycinamidine synthase activity
IC775_14580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC775_14605	COG1473	amidohydrolase
IC775_14650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC775_14685	COG0628	permease
IC775_14695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC775_14700	COG0596	Alpha beta hydrolase
IC775_14705	COG0616	signal peptide processing
IC775_14705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC775_14720	COG1136	(ABC) transporter
IC775_14725	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC775_14760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_14780	COG0463	Glycosyl transferase, family 2
IC775_14790	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC775_14800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC775_14825	COG1280	lysine exporter protein (LysE YggA)
IC775_14840	COG0019	diaminopimelate decarboxylase activity
IC775_14850	COG1113	amino acid transport
IC775_14980	COG0681	Belongs to the peptidase S26 family
IC775_15015	COG4373	Mu-like prophage FluMu protein gp28
IC775_15025	COG4383	Mu-like prophage protein gp29
IC775_15030	COG2369	cell adhesion
IC775_15050	COG4397	Mu-like prophage major head subunit gpT
IC775_15140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC775_15145	COG0243	molybdopterin cofactor binding
IC775_15150	COG1929	Belongs to the glycerate kinase type-1 family
IC775_15165	COG0778	Nitroreductase
IC775_15170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC775_15175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_15200	COG1012	belongs to the aldehyde dehydrogenase family
IC775_15205	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC775_15210	COG0583	DNA-binding transcription factor activity
IC775_15215	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_15220	COG0596	Alpha beta hydrolase
IC775_15225	COG0596	Alpha beta hydrolase
IC775_15225	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC775_15230	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC775_15230	COG0596	Alpha beta hydrolase
IC775_15235	COG1902	pentaerythritol trinitrate reductase activity
IC775_15240	COG1309	transcriptional regulator
IC775_15295	COG3811	Belongs to the UPF0386 family
IC775_15330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC775_15335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_15355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC775_15360	COG0183	Belongs to the thiolase family
IC775_15365	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC775_15370	COG1024	Enoyl-CoA hydratase
IC775_15375	COG1960	acyl-CoA dehydrogenase activity
IC775_15380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC775_15380	COG0644	oxidoreductase
IC775_15450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC775_15480	COG1061	Type III restriction enzyme res subunit
IC775_15530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IC775_15550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC775_15575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC775_15595	COG0741	lytic transglycosylase activity
IC775_15615	COG0584	glycerophosphoryl diester phosphodiesterase
IC775_15620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC775_15645	COG1597	lipid kinase activity
IC775_15660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC775_15665	COG0477	Major facilitator Superfamily
IC775_15715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC775_15720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC775_15745	COG0505	Belongs to the CarA family
IC775_15765	COG0589	response to stress
IC775_15785	COG2321	neutral zinc metallopeptidase
IC775_15790	COG2354	Protein conserved in bacteria
IC775_15835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC775_15840	COG1053	succinate dehydrogenase
IC775_15845	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC775_15850	COG2009	succinate dehydrogenase
IC775_15885	COG2921	Belongs to the UPF0250 family
IC775_15890	COG0321	lipoyl(octanoyl) transferase activity
IC775_15905	COG0531	amino acid
IC775_15915	COG1733	regulation of RNA biosynthetic process
IC775_15920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC775_15925	COG1648	precorrin-2 dehydrogenase activity
IC775_15925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC775_15970	COG0671	phosphoesterase, PA-phosphatase related
IC775_15975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_15985	COG1538	Outer membrane efflux protein
IC775_15990	COG0393	Putative heavy-metal-binding
IC775_15995	COG0393	Putative heavy-metal-binding
IC775_16005	COG1028	Short-chain dehydrogenase reductase Sdr
IC775_16025	COG0525	valine-tRNA ligase activity
IC775_16045	COG0583	DNA-binding transcription factor activity
IC775_16050	COG0004	ammonium transporteR
IC775_16060	COG0642	Histidine kinase
IC775_16065	COG0745	RESPONSE REGULATOR receiver
IC775_16070	COG2194	sulfuric ester hydrolase activity
IC775_16090	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC775_16105	COG2315	Protein conserved in bacteria
IC775_16110	COG0142	geranyltranstransferase activity
IC775_16120	COG1113	amino acid transport
IC775_16125	COG2816	NAD+ diphosphatase activity
IC775_16130	COG3046	protein related to deoxyribodipyrimidine photolyase
IC775_16160	COG2207	Transcriptional regulator
IC775_16185	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC775_16205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC775_16215	COG1530	ribonuclease E activity
IC775_16220	COG0424	maF-like protein
IC775_16225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC775_16230	COG1792	Involved in formation and maintenance of cell shape
IC775_16235	COG1077	Cell shape determining protein MreB Mrl
IC775_16240	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC775_16250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC775_16290	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC775_16295	COG1115	amino acid carrier protein
IC775_16315	COG2814	Major facilitator Superfamily
IC775_16320	COG1289	transmembrane transporter activity
IC775_16370	COG1376	ErfK ybiS ycfS ynhG family protein
IC775_16375	COG2832	Protein of unknown function (DUF454)
IC775_16400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC775_16415	COG0840	transmembrane signaling receptor activity
IC775_16455	COG3422	double-strand break repair
IC775_16460	COG2824	Alkylphosphonate utilization operon protein PhnA
IC775_16465	COG3189	MarR family transcriptional regulator
IC775_16470	COG0596	Alpha beta hydrolase
IC775_16480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC775_16485	COG1335	isochorismatase
IC775_16490	COG0251	oxidation-reduction process
IC775_16495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC775_16500	COG2233	PERMEase
IC775_16515	COG0354	folic acid binding
IC775_16520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC775_16530	COG0679	Auxin Efflux Carrier
IC775_16535	COG1902	pentaerythritol trinitrate reductase activity
IC775_16540	COG4772	TonB-dependent receptor
IC775_16545	COG2094	Belongs to the DNA glycosylase MPG family
IC775_16570	COG1217	gtp-binding protein TYPA
IC775_16575	COG2233	PERMEase
IC775_16585	COG0833	amino acid
IC775_16590	COG1690	Belongs to the RtcB family
IC775_16600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC775_16600	COG2885	chlorophyll binding
IC775_16625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC775_16645	COG2207	Transcriptional regulator
IC775_16670	COG2153	protein acetylation
IC775_16680	COG1272	protein, Hemolysin III
IC775_16685	COG0477	Major facilitator Superfamily
IC775_16700	COG0450	alkyl hydroperoxide reductase
IC775_16770	COG4206	TonB-dependent receptor
IC775_16775	COG2096	Adenosyltransferase
IC775_16795	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC775_16805	COG0745	RESPONSE REGULATOR receiver
IC775_16810	COG2205	protein histidine kinase activity
IC775_16820	COG1960	acyl-CoA dehydrogenase activity
IC775_16825	COG1960	acyl-CoA dehydrogenase activity
IC775_16860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC775_16905	COG0463	Glycosyl transferase, family 2
IC775_16910	COG0726	polysaccharide deacetylase
IC775_16920	COG2194	sulfuric ester hydrolase activity
IC775_16935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC775_16945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC775_16980	COG1862	Preprotein translocase
IC775_16990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC775_16995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC775_17005	COG3781	membrane
IC775_17010	COG0613	PHP domain protein
IC775_17020	COG2350	Protein conserved in bacteria
IC775_17055	COG1607	acyl-coa hydrolase
IC775_17080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC775_17115	COG2199	diguanylate cyclase activity
IC775_17125	COG1408	metallophosphoesterase
IC775_17130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC775_17140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC775_17160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC775_17165	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC775_17170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC775_17175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC775_17180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC775_17190	COG2969	positive regulation of protein catabolic process
IC775_17225	COG1024	Enoyl-CoA hydratase
IC775_17225	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC775_17230	COG1960	acyl-CoA dehydrogenase activity
IC775_17235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC775_17250	COG1309	transcriptional regulator
IC775_17255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC775_17320	COG1183	phosphatidylcholine synthase activity
IC775_17325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC775_17355	COG0739	heme binding
IC775_17355	COG0741	lytic transglycosylase activity
IC775_17355	COG1196	nuclear chromosome segregation
IC775_17365	COG1702	phosphate starvation-inducible protein PhoH
IC775_17400	COG1295	ribonuclease BN
IC775_17410	COG2169	Transcriptional regulator
IC775_17415	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC775_17460	COG0557	exoribonuclease II activity
IC775_17465	COG0339	signal peptide processing
IC775_17470	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC775_17500	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC775_17505	COG1960	acyl-CoA dehydrogenase activity
IC775_17555	COG1841	ribosomal large subunit assembly
IC775_17640	COG0088	Forms part of the polypeptide exit tunnel
IC775_17645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC775_17660	COG0626	cystathionine gamma-synthase activity
IC775_17665	COG0433	COG0433 Predicted ATPase
IC775_17670	COG1017	nitric oxide dioxygenase activity
IC775_17670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC775_17675	COG1959	2 iron, 2 sulfur cluster binding
IC775_17690	COG1301	dicarboxylic acid transport
IC775_17695	COG1946	Acyl-CoA thioesterase
IC775_17700	COG2937	Belongs to the GPAT DAPAT family
IC775_17715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC775_17720	COG1040	competence protein
IC775_17725	COG0494	nUDIX hydrolase
IC775_17735	COG0598	Magnesium transport protein CorA
IC775_17745	COG2854	intermembrane phospholipid transfer
IC775_17755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC775_17760	COG1127	ABC transporter
IC775_17765	COG0513	Belongs to the DEAD box helicase family
IC775_17785	COG0408	coproporphyrinogen oxidase activity
IC775_17800	COG1960	acyl-CoA dehydrogenase activity
IC775_17810	COG1983	PspC domain protein
IC775_17815	COG0517	IMP dehydrogenase activity
IC775_17840	COG0752	glycyl-tRNA synthetase alpha subunit
IC775_17860	COG0583	DNA-binding transcription factor activity
IC775_17865	COG1794	racemase activity, acting on amino acids and derivatives
IC775_17870	COG0583	DNA-binding transcription factor activity
IC775_17910	COG1012	belongs to the aldehyde dehydrogenase family
IC775_17920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC775_17925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC775_17930	COG0833	amino acid
IC775_17935	COG2826	transposase and inactivated derivatives, IS30 family
IC775_17965	COG1192	Involved in chromosome partitioning
IC775_17970	COG0628	permease
IC775_17980	COG1289	transmembrane transporter activity
IC775_18000	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC775_18010	COG0277	FAD linked oxidase domain protein
IC775_18015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC775_18040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC775_18045	COG5380	lipid catabolic process
IC775_18055	COG0335	large ribosomal subunit rRNA binding
IC775_18065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC775_18080	COG4969	Belongs to the N-Me-Phe pilin family
IC775_18105	COG4969	Belongs to the N-Me-Phe pilin family
IC775_18120	COG0194	GDP metabolic process
IC775_18135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC775_18155	COG3307	-O-antigen
IC775_18165	COG4969	Belongs to the N-Me-Phe pilin family
IC775_18175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC775_18180	COG1704	LemA family
IC775_18190	COG0493	'glutamate synthase
IC775_18195	COG0070	glutamate synthase
IC775_18195	COG0067	glutamate synthase
IC775_18195	COG0069	glutamate synthase activity
IC775_18245	COG2226	methyltransferase
IC775_18260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC775_18265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC775_18310	COG0833	amino acid
IC775_18380	COG0488	(ABC) transporter
IC775_18385	COG0028	Belongs to the TPP enzyme family
IC775_18395	COG4221	oxidoreductase activity
IC775_18400	COG0659	secondary active sulfate transmembrane transporter activity
IC775_18430	COG0427	acetyl-CoA hydrolase
IC775_18460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC775_18505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC775_18570	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC775_18575	COG1733	regulation of RNA biosynthetic process
IC775_18605	COG1733	regulation of RNA biosynthetic process
IC775_18625	COG0667	Aldo Keto reductase
IC775_18650	COG2814	Major facilitator Superfamily
IC775_18685	COG1335	isochorismatase
IC775_18695	COG1012	belongs to the aldehyde dehydrogenase family
IC775_18700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC775_18710	COG1113	amino acid transport
IC775_18720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC775_18770	COG2814	Major facilitator Superfamily
IC775_18780	COG0351	phosphomethylpyrimidine kinase
IC775_18780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC775_18780	COG0352	thiamine-phosphate diphosphorylase activity
IC775_18790	COG4221	oxidoreductase activity
IC775_18810	COG1309	transcriptional regulator
IC775_18830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC775_18840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC775_18845	COG3162	membrane
IC775_18875	COG1522	sequence-specific DNA binding
IC775_18880	COG1335	isochorismatase
IC775_18885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC775_18895	COG0668	transmembrane transport
IC775_18900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC775_18910	COG1902	pentaerythritol trinitrate reductase activity
IC775_18930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC775_18955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC775_18955	COG0426	domain, Protein
IC775_18960	COG2119	membrane
IC775_18980	COG4942	peptidase
IC775_18995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC775_19005	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC775_19025	COG0189	ligase activity
IC775_19050	COG0708	Exodeoxyribonuclease III
IC775_19055	COG1393	Belongs to the ArsC family
IC775_19070	COG3706	GGDEF domain
IC775_19085	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC775_19085	COG0666	response to abiotic stimulus
IC775_19105	COG2351	hydroxyisourate hydrolase activity
IC775_19110	COG2233	PERMEase
IC775_19120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC775_19130	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC775_19140	COG3150	esterase
IC775_19195	COG2918	glutathione biosynthetic process
IC775_19210	COG2733	membrane
IC775_19215	COG0436	Aminotransferase
IC775_19220	COG0534	Mate efflux family protein
IC775_19310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC775_19315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC775_19325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC775_19355	COG1280	lysine exporter protein (LysE YggA)
IC775_19365	COG0546	phosphoglycolate phosphatase activity
IC775_19375	COG0010	Belongs to the arginase family
IC775_19405	COG2188	Transcriptional regulator
IC775_19415	COG0523	cobalamin synthesis protein
IC775_19425	COG1113	amino acid transport
IC775_19435	COG0625	glutathione transferase activity
IC775_19440	COG0346	lactoylglutathione lyase activity
IC775_19455	COG1683	Conserved Protein
IC775_19460	COG0534	Mate efflux family protein
IC775_19465	COG0385	Bile acid
IC775_19470	COG1335	isochorismatase
IC775_19475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC775_19500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC775_19505	COG2133	pyrroloquinoline quinone binding
IC775_19510	COG2983	Belongs to the UPF0260 family
IC775_19515	COG5487	UPF0391 membrane protein
IC775_19530	COG1194	a g-specific adenine glycosylase
IC775_19545	COG2818	Glycosylase
IC775_19550	COG1064	alcohol dehydrogenase
IC775_19570	COG0583	DNA-binding transcription factor activity
IC775_19575	COG0656	L-ascorbic acid biosynthetic process
IC775_19580	COG2814	Major facilitator Superfamily
IC775_19615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC775_19630	COG2233	PERMEase
IC775_19670	COG0733	neurotransmitter:sodium symporter activity
IC775_19680	COG0625	glutathione transferase activity
IC775_19710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC775_19715	COG0657	acetylesterase activity
IC775_19765	COG2951	lytic endotransglycosylase activity
IC775_19785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC775_19795	COG0671	phosphoesterase, PA-phosphatase related
IC775_19800	COG0861	Integral membrane protein TerC family
IC775_19810	COG0754	glutathionylspermidine amidase activity
IC775_19820	COG0402	S-adenosylhomocysteine deaminase activity
IC775_19835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC775_19870	COG2205	protein histidine kinase activity
IC775_20035	COG0582	viral genome integration into host DNA
IC775_20055	COG2130	NADP-dependent
IC775_20060	COG1309	transcriptional regulator
IC775_20070	COG1902	pentaerythritol trinitrate reductase activity
IC775_20080	COG1979	alcohol dehydrogenase
IC775_20095	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC775_20125	COG0477	Major facilitator Superfamily
IC775_20140	COG0604	alcohol dehydrogenase
IC775_20140	COG3321	synthase
IC775_20145	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC775_20150	COG0583	DNA-binding transcription factor activity
IC775_20155	COG3328	transposase activity
IC775_20170	COG0659	secondary active sulfate transmembrane transporter activity
IC775_20175	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC775_20210	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC775_20360	COG0789	Transcriptional regulator
IC775_20425	COG2132	Multicopper oxidase
IC775_20495	COG0741	lytic transglycosylase activity
IC775_20525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC775_20760	COG1475	DNA binding