locus-tag	class	description
IC763_00010	COG0592	DNA-directed DNA polymerase activity
IC763_00020	COG0187	DNA topoisomerase II activity
IC763_00030	COG0586	Pfam SNARE associated Golgi protein
IC763_00035	COG0488	(ABC) transporter
IC763_00065	COG3328	transposase activity
IC763_00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC763_00110	COG0625	glutathione transferase activity
IC763_00160	COG2233	PERMEase
IC763_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_00215	COG2814	Major facilitator Superfamily
IC763_00220	COG0656	L-ascorbic acid biosynthetic process
IC763_00225	COG0583	DNA-binding transcription factor activity
IC763_00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_00245	COG1064	alcohol dehydrogenase
IC763_00250	COG2818	Glycosylase
IC763_00265	COG1194	a g-specific adenine glycosylase
IC763_00280	COG5487	UPF0391 membrane protein
IC763_00285	COG2983	Belongs to the UPF0260 family
IC763_00290	COG2133	pyrroloquinoline quinone binding
IC763_00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC763_00300	COG2116	formate transmembrane transporter activity
IC763_00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC763_00325	COG1335	isochorismatase
IC763_00330	COG0385	Bile acid
IC763_00335	COG0534	Mate efflux family protein
IC763_00340	COG1683	Conserved Protein
IC763_00355	COG0346	lactoylglutathione lyase activity
IC763_00360	COG0625	glutathione transferase activity
IC763_00370	COG1113	amino acid transport
IC763_00380	COG0523	cobalamin synthesis protein
IC763_00390	COG2188	Transcriptional regulator
IC763_00420	COG0010	Belongs to the arginase family
IC763_00450	COG3328	transposase activity
IC763_00475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC763_00485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC763_00490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC763_00585	COG0534	Mate efflux family protein
IC763_00590	COG0436	Aminotransferase
IC763_00595	COG2733	membrane
IC763_00610	COG2918	glutathione biosynthetic process
IC763_00670	COG3150	esterase
IC763_00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_00700	COG2233	PERMEase
IC763_00705	COG2351	hydroxyisourate hydrolase activity
IC763_00765	COG1393	Belongs to the ArsC family
IC763_00770	COG0708	Exodeoxyribonuclease III
IC763_00795	COG0189	ligase activity
IC763_00815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC763_00825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC763_00840	COG4942	peptidase
IC763_00850	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_00860	COG2119	membrane
IC763_00865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_00865	COG0426	domain, Protein
IC763_00915	COG1902	pentaerythritol trinitrate reductase activity
IC763_00925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC763_00930	COG0668	transmembrane transport
IC763_00940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC763_00945	COG1335	isochorismatase
IC763_00950	COG1522	sequence-specific DNA binding
IC763_00980	COG3162	membrane
IC763_00985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC763_01015	COG1309	transcriptional regulator
IC763_01035	COG4221	oxidoreductase activity
IC763_01045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC763_01045	COG0352	thiamine-phosphate diphosphorylase activity
IC763_01045	COG0351	phosphomethylpyrimidine kinase
IC763_01055	COG2814	Major facilitator Superfamily
IC763_01070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC763_01080	COG1113	amino acid transport
IC763_01090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC763_01095	COG1012	belongs to the aldehyde dehydrogenase family
IC763_01105	COG1335	isochorismatase
IC763_01165	COG0667	Aldo Keto reductase
IC763_01215	COG1733	regulation of RNA biosynthetic process
IC763_01220	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC763_01235	COG3177	Filamentation induced by cAMP protein fic
IC763_01305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC763_01365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC763_01380	COG2329	Antibiotic biosynthesis monooxygenase
IC763_01415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC763_01445	COG0427	acetyl-CoA hydrolase
IC763_01470	COG0659	secondary active sulfate transmembrane transporter activity
IC763_01475	COG4221	oxidoreductase activity
IC763_01485	COG0028	Belongs to the TPP enzyme family
IC763_01490	COG0488	(ABC) transporter
IC763_01565	COG0833	amino acid
IC763_01610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC763_01615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC763_01630	COG2226	methyltransferase
IC763_01685	COG0493	'glutamate synthase
IC763_01695	COG1704	LemA family
IC763_01700	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC763_01710	COG4969	Belongs to the N-Me-Phe pilin family
IC763_01720	COG3307	-O-antigen
IC763_01740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC763_01755	COG0194	GDP metabolic process
IC763_01770	COG4969	Belongs to the N-Me-Phe pilin family
IC763_01795	COG4969	Belongs to the N-Me-Phe pilin family
IC763_01810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC763_01820	COG0335	large ribosomal subunit rRNA binding
IC763_01830	COG5380	lipid catabolic process
IC763_01835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC763_01860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC763_01875	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC763_01880	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC763_01895	COG1289	transmembrane transporter activity
IC763_01905	COG0628	permease
IC763_01910	COG1192	Involved in chromosome partitioning
IC763_01945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC763_01950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC763_01960	COG1012	belongs to the aldehyde dehydrogenase family
IC763_02005	COG1794	racemase activity, acting on amino acids and derivatives
IC763_02010	COG0583	DNA-binding transcription factor activity
IC763_02030	COG0752	glycyl-tRNA synthetase alpha subunit
IC763_02055	COG0517	IMP dehydrogenase activity
IC763_02060	COG1983	PspC domain protein
IC763_02070	COG1960	acyl-CoA dehydrogenase activity
IC763_02085	COG0408	coproporphyrinogen oxidase activity
IC763_02105	COG0513	Belongs to the DEAD box helicase family
IC763_02110	COG1127	ABC transporter
IC763_02115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC763_02125	COG2854	intermembrane phospholipid transfer
IC763_02135	COG0598	Magnesium transport protein CorA
IC763_02145	COG0494	nUDIX hydrolase
IC763_02150	COG1040	competence protein
IC763_02155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC763_02170	COG2937	Belongs to the GPAT DAPAT family
IC763_02175	COG1946	Acyl-CoA thioesterase
IC763_02180	COG1301	dicarboxylic acid transport
IC763_02195	COG1959	2 iron, 2 sulfur cluster binding
IC763_02205	COG0433	COG0433 Predicted ATPase
IC763_02210	COG0626	cystathionine gamma-synthase activity
IC763_02225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC763_02230	COG0088	Forms part of the polypeptide exit tunnel
IC763_02365	COG1960	acyl-CoA dehydrogenase activity
IC763_02400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC763_02405	COG0339	signal peptide processing
IC763_02410	COG0557	exoribonuclease II activity
IC763_02455	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC763_02460	COG2169	Transcriptional regulator
IC763_02470	COG1295	ribonuclease BN
IC763_02505	COG1702	phosphate starvation-inducible protein PhoH
IC763_02515	COG0739	heme binding
IC763_02515	COG0741	lytic transglycosylase activity
IC763_02515	COG1196	nuclear chromosome segregation
IC763_02545	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC763_02550	COG1183	phosphatidylcholine synthase activity
IC763_02600	COG1960	acyl-CoA dehydrogenase activity
IC763_02605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC763_02610	COG1309	transcriptional regulator
IC763_02625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC763_02630	COG1960	acyl-CoA dehydrogenase activity
IC763_02635	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC763_02635	COG1024	Enoyl-CoA hydratase
IC763_02670	COG2969	positive regulation of protein catabolic process
IC763_02680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC763_02690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC763_02695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC763_02700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC763_02720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC763_02735	COG1408	metallophosphoesterase
IC763_02745	COG2199	diguanylate cyclase activity
IC763_02780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC763_02805	COG1607	acyl-coa hydrolase
IC763_02840	COG2350	Protein conserved in bacteria
IC763_02855	COG3781	membrane
IC763_02865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC763_02870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC763_02880	COG1862	Preprotein translocase
IC763_02930	COG0629	single-stranded DNA binding
IC763_02980	COG3646	Phage regulatory protein
IC763_03135	COG4695	Portal protein
IC763_03150	COG3328	transposase activity
IC763_03160	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC763_03175	COG2194	sulfuric ester hydrolase activity
IC763_03185	COG0726	polysaccharide deacetylase
IC763_03195	COG0438	transferase activity, transferring glycosyl groups
IC763_03235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC763_03270	COG1960	acyl-CoA dehydrogenase activity
IC763_03285	COG2205	protein histidine kinase activity
IC763_03290	COG0745	RESPONSE REGULATOR receiver
IC763_03300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC763_03325	COG4206	TonB-dependent receptor
IC763_03395	COG0450	alkyl hydroperoxide reductase
IC763_03410	COG0477	Major facilitator Superfamily
IC763_03415	COG1272	protein, Hemolysin III
IC763_03425	COG2153	protein acetylation
IC763_03450	COG2207	Transcriptional regulator
IC763_03470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_03485	COG0183	Belongs to the thiolase family
IC763_03495	COG2885	chlorophyll binding
IC763_03495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC763_03505	COG1690	Belongs to the RtcB family
IC763_03520	COG2233	PERMEase
IC763_03550	COG2094	Belongs to the DNA glycosylase MPG family
IC763_03560	COG1902	pentaerythritol trinitrate reductase activity
IC763_03565	COG0679	Auxin Efflux Carrier
IC763_03580	COG0354	folic acid binding
IC763_03595	COG2233	PERMEase
IC763_03600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_03605	COG0251	oxidation-reduction process
IC763_03610	COG1335	isochorismatase
IC763_03615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_03620	COG0778	Nitroreductase
IC763_03625	COG0596	Alpha beta hydrolase
IC763_03630	COG3189	MarR family transcriptional regulator
IC763_03635	COG2824	Alkylphosphonate utilization operon protein PhnA
IC763_03640	COG3422	double-strand break repair
IC763_03680	COG0840	transmembrane signaling receptor activity
IC763_03695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC763_03720	COG2832	Protein of unknown function (DUF454)
IC763_03725	COG1376	ErfK ybiS ycfS ynhG family protein
IC763_03775	COG1289	transmembrane transporter activity
IC763_03780	COG2814	Major facilitator Superfamily
IC763_03800	COG1115	amino acid carrier protein
IC763_03805	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC763_03810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC763_03815	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC763_03845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC763_03855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC763_03860	COG1077	Cell shape determining protein MreB Mrl
IC763_03865	COG1792	Involved in formation and maintenance of cell shape
IC763_03870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC763_03875	COG0424	maF-like protein
IC763_03880	COG1530	ribonuclease E activity
IC763_03890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC763_03910	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC763_03935	COG2207	Transcriptional regulator
IC763_04275	COG0582	viral genome integration into host DNA
IC763_04295	COG3046	protein related to deoxyribodipyrimidine photolyase
IC763_04300	COG2816	NAD+ diphosphatase activity
IC763_04315	COG0142	geranyltranstransferase activity
IC763_04320	COG2315	Protein conserved in bacteria
IC763_04335	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC763_04355	COG2194	sulfuric ester hydrolase activity
IC763_04360	COG0745	RESPONSE REGULATOR receiver
IC763_04365	COG0642	Histidine kinase
IC763_04375	COG0004	ammonium transporteR
IC763_04400	COG0525	valine-tRNA ligase activity
IC763_04410	COG0525	valine-tRNA ligase activity
IC763_04420	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_04430	COG0393	Putative heavy-metal-binding
IC763_04435	COG0393	Putative heavy-metal-binding
IC763_04440	COG1538	Outer membrane efflux protein
IC763_04450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_04455	COG0671	phosphoesterase, PA-phosphatase related
IC763_04485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC763_04500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC763_04500	COG1648	precorrin-2 dehydrogenase activity
IC763_04505	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC763_04520	COG0531	amino acid
IC763_04535	COG0321	lipoyl(octanoyl) transferase activity
IC763_04540	COG2921	Belongs to the UPF0250 family
IC763_04575	COG2009	succinate dehydrogenase
IC763_04585	COG1053	succinate dehydrogenase
IC763_04590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC763_04640	COG2321	neutral zinc metallopeptidase
IC763_04665	COG2843	Capsule synthesis protein
IC763_04685	COG0589	response to stress
IC763_04705	COG0505	Belongs to the CarA family
IC763_04730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC763_04735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC763_04785	COG0477	Major facilitator Superfamily
IC763_04790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC763_04930	COG0732	type I restriction modification DNA specificity domain
IC763_04965	COG0584	glycerophosphoryl diester phosphodiesterase
IC763_04985	COG0741	lytic transglycosylase activity
IC763_05005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC763_05010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC763_05055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC763_05075	COG3811	Belongs to the UPF0386 family
IC763_05130	COG1309	transcriptional regulator
IC763_05135	COG1902	pentaerythritol trinitrate reductase activity
IC763_05140	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_05140	COG0596	Alpha beta hydrolase
IC763_05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_05145	COG0596	Alpha beta hydrolase
IC763_05150	COG0596	Alpha beta hydrolase
IC763_05155	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_05160	COG0583	DNA-binding transcription factor activity
IC763_05165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC763_05170	COG1012	belongs to the aldehyde dehydrogenase family
IC763_05190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_05195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_05200	COG0778	Nitroreductase
IC763_05215	COG1929	Belongs to the glycerate kinase type-1 family
IC763_05220	COG0243	molybdopterin cofactor binding
IC763_05225	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC763_05230	COG3339	Conserved Protein
IC763_05260	COG1113	amino acid transport
IC763_05270	COG0019	diaminopimelate decarboxylase activity
IC763_05285	COG1280	lysine exporter protein (LysE YggA)
IC763_05290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC763_05310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC763_05330	COG0463	Glycosyl transferase, family 2
IC763_05350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_05385	COG1136	(ABC) transporter
IC763_05400	COG0616	signal peptide processing
IC763_05400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC763_05405	COG0596	Alpha beta hydrolase
IC763_05410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC763_05420	COG0628	permease
IC763_05455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC763_05475	COG0823	Involved in the tonB-independent uptake of proteins
IC763_05495	COG0824	Thioesterase
IC763_05525	COG0047	phosphoribosylformylglycinamidine synthase activity
IC763_05525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC763_05535	COG2814	Major facilitator Superfamily
IC763_05555	COG1024	Enoyl-CoA hydratase
IC763_05560	COG1051	belongs to the nudix hydrolase family
IC763_05560	COG1056	cytidyltransferase-related domain
IC763_05575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC763_05590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC763_05595	COG0602	queuosine metabolic process
IC763_05605	COG4625	pathogenesis
IC763_05610	COG0583	DNA-binding transcription factor activity
IC763_05615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC763_05620	COG4208	sulfate ABC transporter
IC763_05625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC763_05635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC763_05645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC763_05665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC763_05675	COG0481	GTPase activity
IC763_05680	COG0681	Belongs to the peptidase S26 family
IC763_05695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC763_05705	COG1381	Involved in DNA repair and RecF pathway recombination
IC763_05710	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC763_05720	COG4221	oxidoreductase activity
IC763_05745	COG0436	Aminotransferase
IC763_05765	COG3706	GGDEF domain
IC763_05770	COG0556	nucleotide-excision repair
IC763_05825	COG2070	2-Nitropropane dioxygenase
IC763_05840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC763_05880	COG1252	NADH dehydrogenase
IC763_05885	COG1686	Belongs to the peptidase S11 family
IC763_05900	COG1187	pseudouridine synthase activity
IC763_06015	COG0305	Participates in initiation and elongation during chromosome replication
IC763_06130	COG3328	transposase activity
IC763_06150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IC763_06185	COG0477	Major facilitator Superfamily
IC763_06195	COG1823	symporter activity
IC763_06230	COG0352	thiamine-phosphate diphosphorylase activity
IC763_06265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_06290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC763_06310	COG3961	Belongs to the TPP enzyme family
IC763_06315	COG1113	amino acid transport
IC763_06325	COG0573	inorganic phosphate transmembrane transporter activity
IC763_06335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC763_06355	COG3647	Membrane
IC763_06380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC763_06385	COG1686	Belongs to the peptidase S11 family
IC763_06410	COG0583	DNA-binding transcription factor activity
IC763_06415	COG1067	ATP-dependent peptidase activity
IC763_06455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC763_06460	COG1966	Carbon starvation protein
IC763_06465	COG2879	small protein
IC763_06505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC763_06535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC763_06540	COG2423	ornithine cyclodeaminase activity
IC763_06550	COG2964	Protein conserved in bacteria
IC763_06565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC763_06575	COG1741	Belongs to the pirin family
IC763_06610	COG0302	gtp cyclohydrolase
IC763_06620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC763_06630	COG2840	Smr protein MutS2
IC763_06645	COG0512	Glutamine amidotransferase of anthranilate synthase
IC763_06660	COG0174	glutamine synthetase
IC763_06670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC763_06705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC763_06710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC763_06715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC763_06740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC763_06760	COG1960	acyl-CoA dehydrogenase activity
IC763_06765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC763_06770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC763_06780	COG2223	nitrite transmembrane transporter activity
IC763_06790	COG0024	Methionine aminopeptidase
IC763_06795	COG0052	Belongs to the universal ribosomal protein uS2 family
IC763_06835	COG2951	lytic endotransglycosylase activity
IC763_06840	COG0772	Belongs to the SEDS family
IC763_06855	COG0842	Transport permease protein
IC763_06865	COG0582	viral genome integration into host DNA
IC763_07020	COG1538	Outer membrane efflux protein
IC763_07030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_07045	COG4215	(ABC) transporter
IC763_07050	COG4160	amino acid transport
IC763_07055	COG4598	ABC transporter
IC763_07065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC763_07070	COG0826	peptidase U32
IC763_07075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_07085	COG2801	Transposase and inactivated derivatives
IC763_07125	COG0642	Histidine kinase
IC763_07135	COG0494	nUDIX hydrolase
IC763_07145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC763_07150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC763_07155	COG3139	Protein of unknown function (DUF1315)
IC763_07165	COG1301	dicarboxylic acid transport
IC763_07170	COG1960	acyl-CoA dehydrogenase activity
IC763_07190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC763_07200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC763_07205	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC763_07225	COG1690	Belongs to the RtcB family
IC763_07230	COG1234	tRNA 3'-trailer cleavage
IC763_07260	COG2363	Small membrane protein
IC763_07290	COG0778	Nitroreductase
IC763_07350	COG1610	YqeY-like protein
IC763_07380	COG0515	serine threonine protein kinase
IC763_07380	COG2815	serine threonine protein kinase
IC763_07405	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IC763_07500	COG1335	isochorismatase
IC763_07505	COG0583	DNA-binding transcription factor activity
IC763_07520	COG0596	Alpha beta hydrolase
IC763_07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC763_07540	COG0786	glutamate:sodium symporter activity
IC763_07550	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_07655	COG2985	domain, Protein
IC763_07680	COG2995	paraquat-inducible protein a
IC763_07685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC763_07685	COG3008	intermembrane lipid transfer
IC763_07695	COG2351	hydroxyisourate hydrolase activity
IC763_07710	COG5002	protein histidine kinase activity
IC763_07755	COG0745	RESPONSE REGULATOR receiver
IC763_07780	COG2175	clavaminate synthase activity
IC763_07785	COG3246	L-lysine catabolic process to acetate
IC763_07790	COG2814	Major facilitator Superfamily
IC763_07805	COG2855	membrane
IC763_07850	COG1301	dicarboxylic acid transport
IC763_07865	COG2011	ABC-type metal ion transport system permease component
IC763_07870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC763_07875	COG1464	Belongs to the NlpA lipoprotein family
IC763_07880	COG0151	Belongs to the GarS family
IC763_07885	COG0138	bifunctional purine biosynthesis protein purh
IC763_07890	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC763_07920	COG2308	Evidence 4 Homologs of previously reported genes of
IC763_07930	COG1305	Transglutaminase-like
IC763_07940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC763_07945	COG0305	Participates in initiation and elongation during chromosome replication
IC763_07970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC763_07980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC763_08015	COG0726	polysaccharide deacetylase
IC763_08015	COG1649	PFAM Uncharacterised BCR, COG1649
IC763_08020	COG1215	transferase activity, transferring glycosyl groups
IC763_08025	COG3658	cytochrome
IC763_08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_08060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_08065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_08080	COG1960	acyl-CoA dehydrogenase activity
IC763_08090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_08115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC763_08120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC763_08125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC763_08130	COG2205	protein histidine kinase activity
IC763_08135	COG0745	RESPONSE REGULATOR receiver
IC763_08140	COG0174	glutamine synthetase
IC763_08160	COG0729	surface antigen
IC763_08190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC763_08195	COG2814	Major facilitator Superfamily
IC763_08205	COG0583	DNA-binding transcription factor activity
IC763_08220	COG1187	pseudouridine synthase activity
IC763_08240	COG0802	atpase or kinase
IC763_08245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC763_08255	COG1923	regulation of RNA biosynthetic process
IC763_08260	COG0697	spore germination
IC763_08285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC763_08290	COG0519	Catalyzes the synthesis of GMP from XMP
IC763_08290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC763_08295	COG4302	ethanolamine ammonia-lyase activity
IC763_08300	COG4303	Ethanolamine ammonia lyase large subunit
IC763_08325	COG1454	alcohol dehydrogenase
IC763_08330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_08340	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC763_08360	COG0308	aminopeptidase N
IC763_08390	COG1605	Chorismate mutase
IC763_08430	COG4264	IucA IucC family
IC763_08435	COG2423	ornithine cyclodeaminase activity
IC763_08440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC763_08450	COG0668	transmembrane transport
IC763_08525	COG1522	sequence-specific DNA binding
IC763_08535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC763_08540	COG0583	DNA-binding transcription factor activity
IC763_08560	COG2030	dehydratase
IC763_08565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC763_08600	COG0824	Thioesterase
IC763_08605	COG1454	alcohol dehydrogenase
IC763_08615	COG1335	isochorismatase
IC763_08630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC763_08695	COG2814	Major facilitator Superfamily
IC763_08710	COG0511	ligase activity, forming carbon-carbon bonds
IC763_08725	COG1116	anion transmembrane transporter activity
IC763_08725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_08730	COG0745	RESPONSE REGULATOR receiver
IC763_08740	COG2146	nitrite reductase [NAD(P)H] activity
IC763_08740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_08745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_08765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC763_08780	COG0315	cyclic pyranopterin monophosphate synthase activity
IC763_08780	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC763_08785	COG0303	'Molybdopterin
IC763_08795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_08820	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC763_08825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC763_08880	COG2204	response regulator
IC763_08910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC763_08915	COG0575	Belongs to the CDS family
IC763_08930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC763_08950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC763_08965	COG2137	regulation of response to DNA damage stimulus
IC763_08975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC763_08980	COG1011	Hydrolase
IC763_08995	COG1522	sequence-specific DNA binding
IC763_09065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC763_09065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC763_09065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC763_09070	COG1105	Belongs to the carbohydrate kinase PfkB family
IC763_09075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC763_09075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC763_09105	COG0024	Methionine aminopeptidase
IC763_09110	COG0583	DNA-binding transcription factor activity
IC763_09120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC763_09125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC763_09155	COG0552	protein localization to endoplasmic reticulum
IC763_09180	COG4890	Cyd operon protein YbgT
IC763_09185	COG1294	oxidase, subunit
IC763_09200	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC763_09210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC763_09215	COG4774	siderophore transport
IC763_09230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC763_09235	COG0569	domain protein
IC763_09240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC763_09270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC763_09275	COG0542	response to heat
IC763_09300	COG1902	pentaerythritol trinitrate reductase activity
IC763_09300	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC763_09340	COG0148	phosphopyruvate hydratase activity
IC763_09345	COG2323	membrane
IC763_09355	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC763_09365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC763_09370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC763_09375	COG0183	Belongs to the thiolase family
IC763_09385	COG0596	Alpha beta hydrolase
IC763_09390	COG2271	Major facilitator Superfamily
IC763_09395	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC763_09405	COG3485	protocatechuate 3,4-dioxygenase
IC763_09415	COG3420	alginic acid biosynthetic process
IC763_09420	COG3659	wide pore channel activity
IC763_09425	COG4993	Dehydrogenase
IC763_09435	COG2391	methyltransferase activity
IC763_09450	COG1414	Transcriptional regulator
IC763_09455	COG0583	DNA-binding transcription factor activity
IC763_09460	COG1960	acyl-CoA dehydrogenase activity
IC763_09485	COG2814	Major facilitator Superfamily
IC763_09495	COG0154	amidase activity
IC763_09515	COG4638	Rieske (2fe-2S)
IC763_09525	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_09535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_09545	COG3733	amine oxidase
IC763_09565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC763_09570	COG0183	Belongs to the thiolase family
IC763_09575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC763_09580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC763_09590	COG4829	muconolactone delta-isomerase
IC763_09595	COG4948	Mandelate Racemase Muconate Lactonizing
IC763_09600	COG0583	DNA-binding transcription factor activity
IC763_09655	COG1309	transcriptional regulator
IC763_09740	COG2271	Major facilitator Superfamily
IC763_09780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC763_09785	COG1120	ATPase activity
IC763_09805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC763_09885	COG2431	L-lysine efflux transmembrane transporter activity
IC763_10030	COG2801	Transposase and inactivated derivatives
IC763_10060	COG0667	Aldo Keto reductase
IC763_10065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_10080	COG2175	clavaminate synthase activity
IC763_10110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_10115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_10120	COG4771	TonB-dependent receptor
IC763_10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_10160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_10165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_10180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC763_10185	COG0805	protein transport
IC763_10195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_10220	COG1132	(ABC) transporter
IC763_10245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC763_10250	COG0601	transmembrane transport
IC763_10280	COG3539	Fimbrial protein
IC763_10305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC763_10325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC763_10330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC763_10340	COG2205	protein histidine kinase activity
IC763_10345	COG0745	RESPONSE REGULATOR receiver
IC763_10350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC763_10355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_10415	COG4771	TonB-dependent receptor
IC763_10420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_10435	COG1169	isochorismate synthase
IC763_10445	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_10455	COG3251	PFAM MbtH domain protein
IC763_10485	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC763_10495	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC763_10505	COG4638	Rieske (2fe-2S)
IC763_10510	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC763_10515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_10515	COG0543	2 iron, 2 sulfur cluster binding
IC763_10530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_10540	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_10560	COG2207	Transcriptional regulator
IC763_10565	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_10570	COG2610	gluconate transmembrane transporter activity
IC763_10575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC763_10610	COG2814	Major facilitator Superfamily
IC763_10630	COG0583	DNA-binding transcription factor activity
IC763_10645	COG2031	fatty acid transporter
IC763_10650	COG0183	Belongs to the thiolase family
IC763_10655	COG0583	DNA-binding transcription factor activity
IC763_10660	COG0583	DNA-binding transcription factor activity
IC763_10675	COG1027	Aspartate ammonia-lyase
IC763_10685	COG0477	Major facilitator Superfamily
IC763_10695	COG3708	Transcriptional regulator
IC763_10695	COG2207	Transcriptional regulator
IC763_10710	COG0730	response to heat
IC763_10720	COG3453	Protein conserved in bacteria
IC763_10720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC763_10730	COG3781	membrane
IC763_10735	COG1063	alcohol dehydrogenase
IC763_10750	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC763_10755	COG0022	dehydrogenase e1 component
IC763_10760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC763_10770	COG3293	Transposase
IC763_10790	COG3706	GGDEF domain
IC763_10805	COG0133	tryptophan synthase activity
IC763_10815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC763_10850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC763_10875	COG2226	methyltransferase
IC763_10925	COG0842	Transport permease protein
IC763_10930	COG0842	Transport permease protein
IC763_10935	COG1131	(ABC) transporter
IC763_10950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC763_10955	COG4773	Receptor
IC763_10975	COG0730	response to heat
IC763_10995	COG0406	alpha-ribazole phosphatase activity
IC763_11020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC763_11035	COG1960	acyl-CoA dehydrogenase activity
IC763_11040	COG1960	acyl-CoA dehydrogenase activity
IC763_11045	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_11050	COG2207	Transcriptional regulator
IC763_11060	COG0776	regulation of translation
IC763_11085	COG0822	iron-sulfur transferase activity
IC763_11090	COG0316	Belongs to the HesB IscA family
IC763_11140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC763_11145	COG0702	epimerase
IC763_11175	COG4172	Belongs to the ABC transporter superfamily
IC763_11180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC763_11185	COG0601	transmembrane transport
IC763_11210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC763_11240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC763_11255	COG2431	L-lysine efflux transmembrane transporter activity
IC763_11270	COG0776	regulation of translation
IC763_11335	COG0084	hydrolase, TatD family'
IC763_11360	COG1132	(ABC) transporter
IC763_11375	COG1475	DNA binding
IC763_11380	COG1192	Involved in chromosome partitioning
IC763_11390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC763_11430	COG0424	maF-like protein
IC763_11455	COG3619	membrane
IC763_11465	COG3328	transposase activity
IC763_11470	COG1132	(ABC) transporter
IC763_11505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC763_11515	COG0506	proline dehydrogenase activity
IC763_11515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC763_11515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC763_11520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC763_11535	COG3698	Phosphodiester glycosidase
IC763_11545	COG2353	YceI-like domain
IC763_11560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC763_11600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC763_11600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC763_11625	COG3539	Fimbrial protein
IC763_11630	COG3121	Chaperone
IC763_11650	COG0697	spore germination
IC763_11660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC763_11670	COG0583	DNA-binding transcription factor activity
IC763_11690	COG2197	response regulator
IC763_11715	COG1522	sequence-specific DNA binding
IC763_11725	COG1126	abc transporter atp-binding protein
IC763_11730	COG0765	amino acid transport
IC763_11735	COG0765	amino acid transport
IC763_11765	COG1464	Belongs to the NlpA lipoprotein family
IC763_11775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC763_11780	COG2011	ABC-type metal ion transport system permease component
IC763_11785	COG0012	GTP binding
IC763_11810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC763_11850	COG0386	Belongs to the glutathione peroxidase family
IC763_11860	COG0436	Aminotransferase
IC763_11865	COG1301	dicarboxylic acid transport
IC763_11900	COG3634	alkyl hydroperoxide reductase activity
IC763_11915	COG0583	DNA-binding transcription factor activity
IC763_11925	COG0210	DNA helicase
IC763_12045	COG3328	transposase activity
IC763_12065	COG0640	Transcriptional regulator
IC763_12080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC763_12090	COG0583	DNA-binding transcription factor activity
IC763_12100	COG1953	Uracil, thiamine, allantoin
IC763_12110	COG2175	clavaminate synthase activity
IC763_12115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_12120	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC763_12125	COG4521	taurine ABC transporter
IC763_12135	COG0477	Major facilitator Superfamily
IC763_12155	COG1271	oxidase subunit
IC763_12160	COG1294	oxidase, subunit
IC763_12170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_12190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC763_12210	COG3052	prosthetic group binding
IC763_12215	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC763_12240	COG1346	cytolysis
IC763_12250	COG0583	DNA-binding transcription factor activity
IC763_12255	COG0625	glutathione transferase activity
IC763_12260	COG0625	glutathione transferase activity
IC763_12265	COG0583	DNA-binding transcription factor activity
IC763_12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC763_12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC763_12310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC763_12320	COG0765	amino acid transport
IC763_12325	COG0765	amino acid transport
IC763_12385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC763_12405	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_12450	COG0583	DNA-binding transcription factor activity
IC763_12470	COG0318	PFAM AMP-dependent synthetase and ligase
IC763_12475	COG1309	transcriptional regulator
IC763_12485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC763_12495	COG4770	biotin carboxylase activity
IC763_12505	COG0583	DNA-binding transcription factor activity
IC763_12520	COG1960	acyl-CoA dehydrogenase activity
IC763_12530	COG2814	Major facilitator Superfamily
IC763_12540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC763_12545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC763_12550	COG2814	Major facilitator Superfamily
IC763_12560	COG1024	Enoyl-CoA hydratase
IC763_12570	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC763_12575	COG0183	Belongs to the thiolase family
IC763_12585	COG2814	Major facilitator Superfamily
IC763_12600	COG1024	Enoyl-CoA hydratase
IC763_12610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC763_12615	COG1960	acyl-CoA dehydrogenase activity
IC763_12620	COG2814	Major facilitator Superfamily
IC763_12625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC763_12630	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC763_12665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_12680	COG0583	DNA-binding transcription factor activity
IC763_12695	COG3038	cytochrome b561
IC763_12705	COG0531	amino acid
IC763_12710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC763_12725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC763_12730	COG1309	transcriptional regulator
IC763_12770	COG3179	chitinase
IC763_12790	COG0406	alpha-ribazole phosphatase activity
IC763_12800	COG2050	protein possibly involved in aromatic compounds catabolism
IC763_12810	COG3327	negative regulation of DNA-templated transcription, initiation
IC763_12815	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC763_12830	COG1024	Enoyl-CoA hydratase
IC763_12840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_12845	COG2151	metal-sulfur cluster biosynthetic enzyme
IC763_12850	COG3396	Phenylacetate-CoA oxygenase
IC763_12855	COG3460	Phenylacetate-CoA oxygenase
IC763_12860	COG3396	Phenylacetate-CoA oxygenase
IC763_12880	COG0789	Transcriptional regulator
IC763_12890	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC763_12895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_12910	COG2807	transmembrane transport
IC763_12915	COG0590	tRNA wobble adenosine to inosine editing
IC763_13020	COG0477	Major facilitator Superfamily
IC763_13035	COG1116	anion transmembrane transporter activity
IC763_13040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC763_13050	COG0864	Transcriptional regulator
IC763_13065	COG1733	regulation of RNA biosynthetic process
IC763_13075	COG0439	Biotin carboxylase
IC763_13090	COG1063	alcohol dehydrogenase
IC763_13125	COG0038	chloride channel
IC763_13130	COG4770	biotin carboxylase activity
IC763_13150	COG1914	H( )-stimulated, divalent metal cation uptake system
IC763_13155	COG0583	DNA-binding transcription factor activity
IC763_13165	COG1595	DNA-templated transcription, initiation
IC763_13190	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_13205	COG2076	Multidrug Resistance protein
IC763_13220	COG3713	MltA-interacting MipA family protein
IC763_13290	COG1011	Hydrolase
IC763_13350	COG1309	transcriptional regulator
IC763_13355	COG1278	Cold shock
IC763_13365	COG0626	cystathionine gamma-synthase activity
IC763_13370	COG1522	sequence-specific DNA binding
IC763_13380	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_13390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC763_13395	COG4774	siderophore transport
IC763_13430	COG0402	S-adenosylhomocysteine deaminase activity
IC763_13435	COG0583	DNA-binding transcription factor activity
IC763_13450	COG1294	oxidase, subunit
IC763_13455	COG1469	GTP cyclohydrolase I activity
IC763_13520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC763_13530	COG4122	O-methyltransferase activity
IC763_13570	COG1538	Outer membrane efflux protein
IC763_13575	COG1137	ATPase activity
IC763_13580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC763_13590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC763_13595	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC763_13595	COG0517	IMP dehydrogenase activity
IC763_13635	COG2814	Major facilitator Superfamily
IC763_13665	COG1278	Cold shock
IC763_13670	COG1280	lysine exporter protein (LysE YggA)
IC763_13790	COG2871	sodium ion transport
IC763_13800	COG0583	DNA-binding transcription factor activity
IC763_13810	COG4638	Rieske (2fe-2S)
IC763_13815	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC763_13820	COG0543	2 iron, 2 sulfur cluster binding
IC763_13820	COG0633	Ferredoxin
IC763_13825	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_13830	COG3135	benzoate transporter
IC763_13865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_13875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IC763_13885	COG3634	alkyl hydroperoxide reductase activity
IC763_13905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC763_13910	COG0625	glutathione transferase activity
IC763_13970	COG1765	OsmC-like protein
IC763_13980	COG0667	Aldo Keto reductase
IC763_13995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC763_14010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC763_14020	COG0527	aspartate kinase activity
IC763_14030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC763_14040	COG3038	cytochrome b561
IC763_14050	COG2252	PERMEase
IC763_14075	COG1741	Belongs to the pirin family
IC763_14080	COG1309	transcriptional regulator
IC763_14095	COG2072	flavoprotein involved in K transport
IC763_14100	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC763_14105	COG0583	DNA-binding transcription factor activity
IC763_14120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC763_14170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC763_14190	COG1024	Enoyl-CoA hydratase
IC763_14195	COG1012	belongs to the aldehyde dehydrogenase family
IC763_14205	COG1960	acyl-CoA dehydrogenase activity
IC763_14225	COG0697	spore germination
IC763_14245	COG1113	amino acid transport
IC763_14285	COG0531	amino acid
IC763_14295	COG1113	amino acid transport
IC763_14330	COG3209	COG3209 Rhs family protein
IC763_14375	COG3293	Transposase
IC763_14405	COG0583	DNA-binding transcription factor activity
IC763_14415	COG0251	oxidation-reduction process
IC763_14430	COG1902	pentaerythritol trinitrate reductase activity
IC763_14430	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC763_14440	COG3706	GGDEF domain
IC763_14440	COG4251	negative regulation of phosphorylation
IC763_14440	COG5001	Diguanylate cyclase
IC763_14440	COG2203	Gaf domain
IC763_14450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC763_14475	COG4172	Belongs to the ABC transporter superfamily
IC763_14480	COG4239	(ABC) transporter, permease
IC763_14485	COG4174	ABC transporter (Permease)
IC763_14495	COG1388	LysM domain
IC763_14495	COG0741	lytic transglycosylase activity
IC763_14540	COG0583	DNA-binding transcription factor activity
IC763_14565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_14570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_14575	COG0006	proline dipeptidase activity
IC763_14610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC763_14635	COG3384	dioxygenase
IC763_14645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC763_14650	COG2878	Part of a membrane complex involved in electron transport
IC763_14655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC763_14680	COG0768	penicillin binding
IC763_14685	COG0742	ribosomal rna small subunit methyltransferase
IC763_14705	COG0830	nickel cation binding
IC763_14715	COG0804	urea catabolic process
IC763_14755	COG1253	flavin adenine dinucleotide binding
IC763_14760	COG2851	Citrate transporter
IC763_14810	COG1773	rubredoxin
IC763_14815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC763_14825	COG0583	DNA-binding transcription factor activity
IC763_14855	COG4181	ATPase activity
IC763_14910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC763_14930	COG0306	phosphate transporter
IC763_14975	COG2223	nitrite transmembrane transporter activity
IC763_14985	COG2066	Belongs to the glutaminase family
IC763_14990	COG0242	peptide deformylase activity
IC763_14995	COG0477	Major facilitator Superfamily
IC763_15005	COG0028	Belongs to the TPP enzyme family
IC763_15020	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_15025	COG2267	carboxylic ester hydrolase activity
IC763_15070	COG1414	Transcriptional regulator
IC763_15105	COG3328	transposase activity
IC763_15120	COG1215	transferase activity, transferring glycosyl groups
IC763_15125	COG0726	polysaccharide deacetylase
IC763_15125	COG1649	PFAM Uncharacterised BCR, COG1649
IC763_15135	COG4681	YaeQ
IC763_15145	COG0523	cobalamin synthesis protein
IC763_15155	COG1607	acyl-coa hydrolase
IC763_15165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC763_15170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC763_15175	COG1309	transcriptional regulator
IC763_15200	COG2040	homocysteine
IC763_15205	COG0531	amino acid
IC763_15225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC763_15310	COG0405	Gamma-glutamyltransferase
IC763_15315	COG2814	Major facilitator Superfamily
IC763_15325	COG2050	protein possibly involved in aromatic compounds catabolism
IC763_15340	COG1090	epimerase
IC763_15360	COG0420	3'-5' exonuclease activity
IC763_15370	COG1968	undecaprenyl-diphosphatase activity
IC763_15390	COG0735	belongs to the Fur family
IC763_15395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC763_15400	COG2914	Belongs to the UPF0125 (RnfH) family
IC763_15415	COG0121	glutamine amidotransferase
IC763_15430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC763_15445	COG2885	chlorophyll binding
IC763_15450	COG0204	Acyl-transferase
IC763_15465	COG2894	cell division
IC763_15480	COG1280	lysine exporter protein (LysE YggA)
IC763_15485	COG1674	ftsk spoiiie
IC763_15490	COG0492	ferredoxin-NADP+ reductase activity
IC763_15495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC763_15505	COG0456	acetyltransferase
IC763_15525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC763_15535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC763_15550	COG1981	membrane
IC763_15560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC763_15560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC763_15580	COG1012	belongs to the aldehyde dehydrogenase family
IC763_15585	COG4638	Rieske (2fe-2S)
IC763_15600	COG0473	3-isopropylmalate dehydrogenase activity
IC763_15605	COG0583	DNA-binding transcription factor activity
IC763_15625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC763_15650	COG0564	pseudouridine synthase activity
IC763_15660	COG0358	DNA primase activity
IC763_15675	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC763_15705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC763_15735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC763_15750	COG1652	LysM domain
IC763_15775	COG1399	metal-binding, possibly nucleic acid-binding protein
IC763_15780	COG3101	peptidyl-lysine hydroxylation
IC763_15785	COG0009	L-threonylcarbamoyladenylate synthase
IC763_15790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC763_15795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC763_15810	COG4106	trans-aconitate 2-methyltransferase activity
IC763_15825	COG2226	methyltransferase
IC763_15825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC763_15825	COG0596	Alpha beta hydrolase
IC763_15830	COG1877	trehalose-phosphatase activity
IC763_15835	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC763_15840	COG2223	nitrite transmembrane transporter activity
IC763_15870	COG0730	response to heat
IC763_15885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC763_15895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC763_15940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC763_15945	COG0489	protein tyrosine kinase activity
IC763_15955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC763_15955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC763_15990	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC763_15995	COG2081	HI0933 family
IC763_16005	COG0668	transmembrane transport
IC763_16025	COG0583	DNA-binding transcription factor activity
IC763_16050	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC763_16055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC763_16070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC763_16085	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC763_16110	COG3706	GGDEF domain
IC763_16125	COG0745	RESPONSE REGULATOR receiver
IC763_16145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC763_16175	COG3328	transposase activity
IC763_16180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC763_16195	COG0384	phenazine biosynthesis protein PhzF
IC763_16210	COG3128	pkhd-type hydroxylase
IC763_16240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC763_16265	COG0583	DNA-binding transcription factor activity
IC763_16285	COG1053	succinate dehydrogenase
IC763_16300	COG1309	transcriptional regulator
IC763_16310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC763_16315	COG2814	Major facilitator Superfamily
IC763_16320	COG1960	acyl-CoA dehydrogenase activity
IC763_16325	COG0583	DNA-binding transcription factor activity
IC763_16365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC763_16385	COG2132	Multicopper oxidase
IC763_16395	COG0561	phosphatase activity
IC763_16400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC763_16410	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC763_16425	COG1214	PFAM Peptidase M22, glycoprotease
IC763_16475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC763_16485	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC763_16490	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC763_16495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC763_16555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC763_16565	COG1846	Transcriptional regulator
IC763_16570	COG1764	response to oxidative stress
IC763_16610	COG0037	tRNA processing
IC763_16620	COG0248	Ppx GppA phosphatase
IC763_16650	COG0072	phenylalanine-tRNA ligase activity
IC763_16680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC763_16690	COG1238	metal cluster binding
IC763_16695	COG0625	glutathione transferase activity
IC763_16710	COG0318	PFAM AMP-dependent synthetase and ligase
IC763_16715	COG3028	Belongs to the UPF0307 family
IC763_16740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC763_16745	COG0617	tRNA 3'-terminal CCA addition
IC763_16750	COG1555	photosystem II stabilization
IC763_16755	COG3956	TIGRFAM MazG family protein
IC763_16765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC763_16785	COG5002	protein histidine kinase activity
IC763_16785	COG0784	Response regulator, receiver
IC763_16785	COG2205	protein histidine kinase activity
IC763_16790	COG1024	Enoyl-CoA hydratase
IC763_16795	COG2084	Dehydrogenase
IC763_16800	COG3622	Belongs to the hyi family
IC763_16835	COG0697	spore germination
IC763_16845	COG2814	Major facilitator Superfamily
IC763_16855	COG3328	transposase activity
IC763_16865	COG0492	ferredoxin-NADP+ reductase activity
IC763_16870	COG0431	NADPH-dependent FMN reductase
IC763_16875	COG0798	PFAM Bile acid sodium symporter
IC763_16885	COG0640	Transcriptional regulator
IC763_16945	COG2205	protein histidine kinase activity
IC763_16980	COG3328	transposase activity
IC763_16990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC763_17000	COG0583	DNA-binding transcription factor activity
IC763_17010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC763_17090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC763_17100	COG1061	Type III restriction enzyme res subunit
IC763_17105	COG1002	Type II restriction enzyme, methylase subunits
IC763_17110	COG0084	hydrolase, TatD family'
IC763_17220	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC763_17225	COG0440	acetolactate synthase activity
IC763_17260	COG1136	(ABC) transporter
IC763_17260	COG0577	efflux transmembrane transporter activity
IC763_17265	COG1538	Outer membrane efflux protein
IC763_17280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC763_17295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC763_17370	COG0793	Belongs to the peptidase S41A family
IC763_17400	COG3265	gluconokinase activity
IC763_17410	COG0800	Aldolase
IC763_17425	COG0857	belongs to the CobB CobQ family
IC763_17425	COG0280	phosphate acetyltransferase
IC763_17430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC763_17430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC763_17450	COG0740	serine-type endopeptidase activity
IC763_17460	COG4774	siderophore transport
IC763_17470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC763_17480	COG2813	Specifically methylates the guanine in position
IC763_17480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC763_17575	COG0788	formyltetrahydrofolate deformylase activity
IC763_17600	COG4651	solute:proton antiporter activity
IC763_17600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC763_17620	COG0724	RNA recognition motif
IC763_17625	COG0210	DNA helicase
IC763_17650	COG1733	regulation of RNA biosynthetic process
IC763_17660	COG2900	Belongs to the SlyX family
IC763_17665	COG0488	(ABC) transporter
IC763_17675	COG1280	lysine exporter protein (LysE YggA)
IC763_17680	COG1560	Kdo2-lipid A biosynthetic process
IC763_17690	COG1301	dicarboxylic acid transport
IC763_17745	COG0473	3-isopropylmalate dehydrogenase activity
IC763_17770	COG0583	DNA-binding transcription factor activity
IC763_17815	COG0583	DNA-binding transcription factor activity
IC763_17825	COG0625	glutathione transferase activity
IC763_17830	COG2378	regulation of single-species biofilm formation
IC763_17845	COG1530	ribonuclease E activity
IC763_17850	COG0318	PFAM AMP-dependent synthetase and ligase
IC763_17865	COG0583	DNA-binding transcription factor activity
IC763_17870	COG4221	oxidoreductase activity
IC763_17885	COG0534	Mate efflux family protein
IC763_17900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC763_17930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC763_17930	COG0493	'glutamate synthase
IC763_17940	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC763_17960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC763_17970	COG0644	oxidoreductase
IC763_17970	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC763_17990	COG4535	Mg2 and Co2 transporter CorC
IC763_18000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC763_18025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC763_18030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC763_18030	COG0475	glutathione-regulated potassium exporter activity
IC763_18035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC763_18045	COG0484	heat shock protein binding
IC763_18050	COG0789	Transcriptional regulator
IC763_18055	COG0598	Magnesium transport protein CorA
IC763_18060	COG1185	polyribonucleotide nucleotidyltransferase activity
IC763_18070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC763_18075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_18080	COG1074	ATP-dependent DNA helicase activity
IC763_18085	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC763_18110	COG2226	methyltransferase
IC763_18125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC763_18140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC763_18155	COG2111	Na H antiporter
IC763_18155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC763_18160	COG1006	Multisubunit Na H antiporter MnhC subunit
IC763_18165	COG0651	ATP synthesis coupled electron transport
IC763_18170	COG1863	multisubunit Na H antiporter MnhE subunit
IC763_18175	COG2212	antiporter activity
IC763_18180	COG1320	monovalent cation:proton antiporter activity
IC763_18185	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC763_18195	COG0195	Participates in both transcription termination and antitermination
IC763_18255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC763_18265	COG0497	DNA recombination
IC763_18275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC763_18290	COG1289	transmembrane transporter activity
IC763_18305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC763_18365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC763_18380	COG0326	Molecular chaperone. Has ATPase activity
IC763_18400	COG0596	Alpha beta hydrolase
IC763_18495	COG0546	phosphoglycolate phosphatase activity
IC763_18500	COG1716	ATPase activity
IC763_18545	COG0181	hydroxymethylbilane synthase activity
IC763_18575	COG1538	Outer membrane efflux protein
IC763_18585	COG0697	spore germination
IC763_18605	COG0494	nUDIX hydrolase
IC763_18615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC763_18620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC763_18625	COG0772	Belongs to the SEDS family
IC763_18650	COG4974	Belongs to the 'phage' integrase family
IC763_18665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC763_18675	COG2197	response regulator
IC763_18695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC763_18700	COG0795	lipopolysaccharide-transporting ATPase activity
IC763_18705	COG0795	lipopolysaccharide-transporting ATPase activity
IC763_18740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC763_18740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC763_18750	COG0004	ammonium transporteR
IC763_18755	COG0347	Belongs to the P(II) protein family
IC763_18765	COG0606	chelatase, subunit chli
IC763_18770	COG0431	NADPH-dependent FMN reductase
IC763_18775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC763_18780	COG0235	Class ii aldolase
IC763_18785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC763_18800	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC763_18825	COG0477	Major facilitator Superfamily
IC763_18830	COG2860	membrane
IC763_18840	COG1253	flavin adenine dinucleotide binding
IC763_18850	COG2814	Major facilitator Superfamily
IC763_18860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC763_18895	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC763_18910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC763_18945	COG1309	transcriptional regulator
IC763_18980	COG0758	DNA mediated transformation
IC763_18990	COG0697	spore germination
IC763_18995	COG1309	transcriptional regulator
IC763_19010	COG0386	Belongs to the glutathione peroxidase family
IC763_19020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC763_19025	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC763_19075	COG1121	(ABC) transporter
IC763_19080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC763_19085	COG1280	lysine exporter protein (LysE YggA)
IC763_19090	COG2837	iron assimilation
IC763_19100	COG0281	malic enzyme
IC763_19135	COG0735	belongs to the Fur family
IC763_19145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC763_19150	COG0519	Catalyzes the synthesis of GMP from XMP
IC763_19150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC763_19155	COG4399	Belongs to the UPF0754 family
IC763_19160	COG2259	Doxx family
IC763_19165	COG0586	Pfam SNARE associated Golgi protein
IC763_19180	COG1192	Involved in chromosome partitioning
IC763_19190	COG0271	Belongs to the BolA IbaG family
IC763_19225	COG3756	Protein conserved in bacteria
IC763_19235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC763_19300	COG3550	peptidyl-serine autophosphorylation
IC763_19305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC763_19310	COG2963	transposase activity
IC763_19320	COG4372	Transposase
IC763_19400	COG3321	synthase
IC763_19400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC763_19400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC763_19400	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC763_19405	COG1960	acyl-CoA dehydrogenase activity
IC763_19420	COG2197	response regulator
IC763_19430	COG3916	Acyl-homoserine-lactone synthase
IC763_19435	COG0477	Major facilitator Superfamily
IC763_19440	COG1024	Enoyl-CoA hydratase
IC763_19445	COG1024	Enoyl-CoA hydratase
IC763_19450	COG1960	acyl-CoA dehydrogenase activity
IC763_19455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC763_19475	COG1113	amino acid transport
IC763_19480	COG1113	amino acid transport
IC763_19485	COG0251	oxidation-reduction process
IC763_19525	COG0564	pseudouridine synthase activity
IC763_19545	COG3328	transposase activity
IC763_19600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC763_19615	COG1802	Transcriptional regulator
IC763_19625	COG1448	Aminotransferase
IC763_19630	COG0277	FAD linked oxidase domain protein
IC763_19640	COG2186	Transcriptional regulator
IC763_19650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC763_19660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC763_19675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC763_19685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IC763_19745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC763_19765	COG1596	polysaccharide export
IC763_19790	COG0728	peptidoglycan biosynthetic process
IC763_19795	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC763_19850	COG0546	phosphoglycolate phosphatase activity
IC763_19855	COG1028	Short-chain dehydrogenase reductase Sdr
IC763_19870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC763_19870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC763_19875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_19880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC763_19885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC763_19890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC763_19895	COG1116	anion transmembrane transporter activity
IC763_19900	COG1309	transcriptional regulator
IC763_19905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC763_19915	COG0196	riboflavin kinase activity
IC763_19920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC763_19930	COG1047	Peptidyl-prolyl cis-trans
IC763_19970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC763_19975	COG0657	acetylesterase activity
IC763_20030	COG2951	lytic endotransglycosylase activity
IC763_20035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC763_20050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC763_20060	COG0671	phosphoesterase, PA-phosphatase related
IC763_20065	COG0861	Integral membrane protein TerC family
IC763_20075	COG0402	S-adenosylhomocysteine deaminase activity
IC763_20090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC763_20300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC763_20380	COG2826	transposase and inactivated derivatives, IS30 family
IC763_20390	COG2826	transposase and inactivated derivatives, IS30 family
IC763_20555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC763_20610	COG1525	nuclease
IC763_20620	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IC763_20625	COG3421	Type III restriction
IC763_20690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC763_20775	COG0860	N-Acetylmuramoyl-L-alanine amidase
IC763_20835	COG1538	Outer membrane efflux protein
IC763_20840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC763_20850	COG0745	RESPONSE REGULATOR receiver
IC763_20875	COG0488	(ABC) transporter
IC763_20895	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_20900	COG3657	addiction module killer protein
IC763_20950	COG0659	secondary active sulfate transmembrane transporter activity
IC763_20955	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_20960	COG3657	addiction module killer protein
IC763_21015	COG2814	Major facilitator Superfamily
IC763_21030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC763_21035	COG2076	Multidrug Resistance protein
IC763_21070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC763_21090	COG4372	Transposase
IC763_21385	COG1192	Involved in chromosome partitioning
IC763_21390	COG1475	DNA binding
IC763_21615	COG0789	Transcriptional regulator
IC763_21790	COG3328	transposase activity
IC763_21860	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC763_21885	COG4221	oxidoreductase activity
IC763_21890	COG0583	DNA-binding transcription factor activity
IC763_21900	COG3321	synthase
IC763_21900	COG0604	alcohol dehydrogenase
IC763_21905	COG0583	DNA-binding transcription factor activity
IC763_21915	COG3657	addiction module killer protein
IC763_21920	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_21940	COG3657	addiction module killer protein
IC763_21945	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC763_21965	COG1063	alcohol dehydrogenase
IC763_21995	COG1979	alcohol dehydrogenase
IC763_22005	COG1902	pentaerythritol trinitrate reductase activity
IC763_22015	COG1309	transcriptional regulator
IC763_22020	COG2130	NADP-dependent
IC763_22035	COG0582	viral genome integration into host DNA
IC763_22105	COG0589	response to stress