locus-tag	class	description
IC780_00010	COG0592	DNA-directed DNA polymerase activity
IC780_00020	COG0187	DNA topoisomerase II activity
IC780_00030	COG0586	Pfam SNARE associated Golgi protein
IC780_00035	COG0488	(ABC) transporter
IC780_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC780_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC780_00110	COG1047	Peptidyl-prolyl cis-trans
IC780_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC780_00125	COG0196	riboflavin kinase activity
IC780_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC780_00140	COG1309	transcriptional regulator
IC780_00145	COG1116	anion transmembrane transporter activity
IC780_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_00170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC780_00170	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC780_00185	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_00190	COG0546	phosphoglycolate phosphatase activity
IC780_00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC780_00250	COG0728	peptidoglycan biosynthetic process
IC780_00275	COG1596	polysaccharide export
IC780_00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC780_00290	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC780_00295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC780_00305	COG1086	Polysaccharide biosynthesis protein
IC780_00340	COG1216	Glycosyl transferase, family 2
IC780_00340	COG0463	Glycosyl transferase, family 2
IC780_00345	COG0110	maltose O-acetyltransferase activity
IC780_00360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC780_00365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC780_00390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC780_00400	COG2186	Transcriptional regulator
IC780_00410	COG0277	FAD linked oxidase domain protein
IC780_00415	COG1448	Aminotransferase
IC780_00425	COG1802	Transcriptional regulator
IC780_00440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC780_00510	COG0564	pseudouridine synthase activity
IC780_00550	COG0251	oxidation-reduction process
IC780_00555	COG1113	amino acid transport
IC780_00560	COG1113	amino acid transport
IC780_00580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC780_00585	COG1960	acyl-CoA dehydrogenase activity
IC780_00590	COG1024	Enoyl-CoA hydratase
IC780_00595	COG1024	Enoyl-CoA hydratase
IC780_00600	COG0477	Major facilitator Superfamily
IC780_00605	COG3916	Acyl-homoserine-lactone synthase
IC780_00615	COG2197	response regulator
IC780_00625	COG1960	acyl-CoA dehydrogenase activity
IC780_00630	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC780_00630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC780_00630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC780_00630	COG3321	synthase
IC780_00670	COG0271	Belongs to the BolA IbaG family
IC780_00680	COG1192	Involved in chromosome partitioning
IC780_00695	COG0586	Pfam SNARE associated Golgi protein
IC780_00700	COG2259	Doxx family
IC780_00705	COG4399	Belongs to the UPF0754 family
IC780_00705	COG4399	Belongs to the UPF0754 family
IC780_00710	COG0519	Catalyzes the synthesis of GMP from XMP
IC780_00710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC780_00715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC780_00725	COG0735	belongs to the Fur family
IC780_00760	COG0281	malic enzyme
IC780_00770	COG2826	transposase and inactivated derivatives, IS30 family
IC780_00780	COG1280	lysine exporter protein (LysE YggA)
IC780_00790	COG1121	(ABC) transporter
IC780_00840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC780_00845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC780_00855	COG0386	Belongs to the glutathione peroxidase family
IC780_00870	COG1309	transcriptional regulator
IC780_00875	COG0697	spore germination
IC780_00885	COG0758	DNA mediated transformation
IC780_00920	COG1309	transcriptional regulator
IC780_00955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC780_00970	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC780_01015	COG2814	Major facilitator Superfamily
IC780_01025	COG1253	flavin adenine dinucleotide binding
IC780_01035	COG2860	membrane
IC780_01040	COG0477	Major facilitator Superfamily
IC780_01050	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_01065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC780_01080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC780_01085	COG0235	Class ii aldolase
IC780_01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_01095	COG0431	NADPH-dependent FMN reductase
IC780_01100	COG0606	chelatase, subunit chli
IC780_01110	COG0347	Belongs to the P(II) protein family
IC780_01115	COG0004	ammonium transporteR
IC780_01125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC780_01125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC780_01160	COG0795	lipopolysaccharide-transporting ATPase activity
IC780_01165	COG0795	lipopolysaccharide-transporting ATPase activity
IC780_01170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC780_01175	COG0793	Belongs to the peptidase S41A family
IC780_01190	COG2197	response regulator
IC780_01200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC780_01210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC780_01215	COG4974	Belongs to the 'phage' integrase family
IC780_01245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC780_01250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC780_01260	COG0494	nUDIX hydrolase
IC780_01280	COG0697	spore germination
IC780_01290	COG1538	Outer membrane efflux protein
IC780_01310	COG3275	phosphorelay sensor kinase activity
IC780_01320	COG0181	hydroxymethylbilane synthase activity
IC780_01365	COG1716	ATPase activity
IC780_01370	COG0546	phosphoglycolate phosphatase activity
IC780_01465	COG0596	Alpha beta hydrolase
IC780_01470	COG2056	Na+-H+ antiporter family
IC780_01485	COG0326	Molecular chaperone. Has ATPase activity
IC780_01500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC780_01560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC780_01575	COG1289	transmembrane transporter activity
IC780_01590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC780_01600	COG0497	DNA recombination
IC780_01610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC780_01620	COG0237	dephospho-CoA kinase activity
IC780_01670	COG0195	Participates in both transcription termination and antitermination
IC780_01680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC780_01685	COG1320	monovalent cation:proton antiporter activity
IC780_01690	COG2212	antiporter activity
IC780_01695	COG1863	multisubunit Na H antiporter MnhE subunit
IC780_01700	COG0651	ATP synthesis coupled electron transport
IC780_01705	COG1006	Multisubunit Na H antiporter MnhC subunit
IC780_01710	COG2111	Na H antiporter
IC780_01710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC780_01725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC780_01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_01755	COG2226	methyltransferase
IC780_01780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC780_01785	COG1074	ATP-dependent DNA helicase activity
IC780_01790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC780_01795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC780_01805	COG1185	polyribonucleotide nucleotidyltransferase activity
IC780_01810	COG0598	Magnesium transport protein CorA
IC780_01815	COG0789	Transcriptional regulator
IC780_01820	COG0484	heat shock protein binding
IC780_01830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC780_01835	COG0475	glutathione-regulated potassium exporter activity
IC780_01835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC780_01840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC780_01865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC780_01875	COG4535	Mg2 and Co2 transporter CorC
IC780_01890	COG0644	oxidoreductase
IC780_01890	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC780_01900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC780_01915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_01920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC780_01930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC780_01930	COG0493	'glutamate synthase
IC780_01960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC780_01975	COG0534	Mate efflux family protein
IC780_01985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC780_01990	COG4221	oxidoreductase activity
IC780_01995	COG0583	DNA-binding transcription factor activity
IC780_02010	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_02015	COG1530	ribonuclease E activity
IC780_02030	COG2378	regulation of single-species biofilm formation
IC780_02035	COG0625	glutathione transferase activity
IC780_02045	COG0583	DNA-binding transcription factor activity
IC780_02090	COG0583	DNA-binding transcription factor activity
IC780_02115	COG0473	3-isopropylmalate dehydrogenase activity
IC780_02170	COG1301	dicarboxylic acid transport
IC780_02180	COG1560	Kdo2-lipid A biosynthetic process
IC780_02185	COG1280	lysine exporter protein (LysE YggA)
IC780_02195	COG0488	(ABC) transporter
IC780_02200	COG2900	Belongs to the SlyX family
IC780_02210	COG1733	regulation of RNA biosynthetic process
IC780_02235	COG0210	DNA helicase
IC780_02240	COG0724	RNA recognition motif
IC780_02260	COG4651	solute:proton antiporter activity
IC780_02260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC780_02285	COG0788	formyltetrahydrofolate deformylase activity
IC780_02390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC780_02390	COG2813	Specifically methylates the guanine in position
IC780_02400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC780_02410	COG4774	siderophore transport
IC780_02420	COG0740	serine-type endopeptidase activity
IC780_02440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC780_02440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC780_02445	COG0857	belongs to the CobB CobQ family
IC780_02445	COG0280	phosphate acetyltransferase
IC780_02450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC780_02460	COG0800	Aldolase
IC780_02470	COG3265	gluconokinase activity
IC780_02475	COG1012	belongs to the aldehyde dehydrogenase family
IC780_02485	COG2267	carboxylic ester hydrolase activity
IC780_02500	COG0793	Belongs to the peptidase S41A family
IC780_02535	COG1426	Protein conserved in bacteria
IC780_02575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC780_02585	COG1162	GTPase activity
IC780_02590	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC780_02605	COG1538	Outer membrane efflux protein
IC780_02610	COG1136	(ABC) transporter
IC780_02610	COG0577	efflux transmembrane transporter activity
IC780_02640	COG0028	Belongs to the TPP enzyme family
IC780_02645	COG0440	acetolactate synthase activity
IC780_02650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC780_02685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC780_02700	COG0084	hydrolase, TatD family'
IC780_02710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC780_02720	COG0583	DNA-binding transcription factor activity
IC780_02730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC780_02835	COG2814	Major facilitator Superfamily
IC780_02850	COG1230	cation diffusion facilitator family transporter
IC780_02875	COG2814	Major facilitator Superfamily
IC780_02885	COG0697	spore germination
IC780_02920	COG3622	Belongs to the hyi family
IC780_02925	COG2084	Dehydrogenase
IC780_02930	COG1024	Enoyl-CoA hydratase
IC780_02935	COG2205	protein histidine kinase activity
IC780_02935	COG5002	protein histidine kinase activity
IC780_02935	COG0784	Response regulator, receiver
IC780_02955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC780_02965	COG3956	TIGRFAM MazG family protein
IC780_02970	COG1555	photosystem II stabilization
IC780_02975	COG0617	tRNA 3'-terminal CCA addition
IC780_02980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC780_03005	COG3028	Belongs to the UPF0307 family
IC780_03010	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_03025	COG0625	glutathione transferase activity
IC780_03030	COG1238	metal cluster binding
IC780_03040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC780_03070	COG0072	phenylalanine-tRNA ligase activity
IC780_03100	COG0248	Ppx GppA phosphatase
IC780_03150	COG1764	response to oxidative stress
IC780_03155	COG1846	Transcriptional regulator
IC780_03165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC780_03225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC780_03230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC780_03235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC780_03245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC780_03295	COG1214	PFAM Peptidase M22, glycoprotease
IC780_03310	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC780_03320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC780_03325	COG0561	phosphatase activity
IC780_03335	COG2132	Multicopper oxidase
IC780_03360	COG2826	transposase and inactivated derivatives, IS30 family
IC780_03370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC780_03375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC780_03405	COG1063	alcohol dehydrogenase
IC780_03410	COG0583	DNA-binding transcription factor activity
IC780_03415	COG1960	acyl-CoA dehydrogenase activity
IC780_03420	COG2814	Major facilitator Superfamily
IC780_03425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC780_03435	COG1309	transcriptional regulator
IC780_03450	COG1053	succinate dehydrogenase
IC780_03455	COG0583	DNA-binding transcription factor activity
IC780_03470	COG0583	DNA-binding transcription factor activity
IC780_03480	COG0583	DNA-binding transcription factor activity
IC780_03495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_03540	COG0583	DNA-binding transcription factor activity
IC780_03545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC780_03575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC780_03595	COG0745	RESPONSE REGULATOR receiver
IC780_03610	COG3706	GGDEF domain
IC780_03635	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC780_03650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC780_03665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC780_03670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC780_03695	COG0583	DNA-binding transcription factor activity
IC780_03715	COG0668	transmembrane transport
IC780_03725	COG2081	HI0933 family
IC780_03730	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC780_03765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC780_03765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC780_03775	COG0489	protein tyrosine kinase activity
IC780_03780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC780_03825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC780_03835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC780_03850	COG0730	response to heat
IC780_03860	COG1196	nuclear chromosome segregation
IC780_03880	COG2223	nitrite transmembrane transporter activity
IC780_03885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC780_03890	COG1877	trehalose-phosphatase activity
IC780_03895	COG2226	methyltransferase
IC780_03895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC780_03895	COG0596	Alpha beta hydrolase
IC780_03910	COG4106	trans-aconitate 2-methyltransferase activity
IC780_03925	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC780_03930	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC780_03935	COG0009	L-threonylcarbamoyladenylate synthase
IC780_03940	COG3101	peptidyl-lysine hydroxylation
IC780_03945	COG1399	metal-binding, possibly nucleic acid-binding protein
IC780_03970	COG1652	LysM domain
IC780_03975	COG0351	phosphomethylpyrimidine kinase
IC780_03975	COG0352	thiamine-phosphate diphosphorylase activity
IC780_03975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC780_03985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC780_04015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC780_04045	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC780_04060	COG0358	DNA primase activity
IC780_04070	COG0564	pseudouridine synthase activity
IC780_04095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC780_04115	COG0583	DNA-binding transcription factor activity
IC780_04120	COG0473	3-isopropylmalate dehydrogenase activity
IC780_04130	COG0657	acetylesterase activity
IC780_04135	COG4638	Rieske (2fe-2S)
IC780_04140	COG1012	belongs to the aldehyde dehydrogenase family
IC780_04160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC780_04160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC780_04170	COG1981	membrane
IC780_04185	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC780_04195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC780_04215	COG0456	acetyltransferase
IC780_04225	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC780_04230	COG0492	ferredoxin-NADP+ reductase activity
IC780_04235	COG1674	ftsk spoiiie
IC780_04240	COG1280	lysine exporter protein (LysE YggA)
IC780_04255	COG2894	cell division
IC780_04270	COG0204	Acyl-transferase
IC780_04275	COG2885	chlorophyll binding
IC780_04280	COG0210	DNA helicase
IC780_04290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC780_04305	COG0121	glutamine amidotransferase
IC780_04320	COG2914	Belongs to the UPF0125 (RnfH) family
IC780_04325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC780_04330	COG0735	belongs to the Fur family
IC780_04350	COG1968	undecaprenyl-diphosphatase activity
IC780_04360	COG0420	3'-5' exonuclease activity
IC780_04380	COG1090	epimerase
IC780_04395	COG2050	protein possibly involved in aromatic compounds catabolism
IC780_04405	COG2814	Major facilitator Superfamily
IC780_04410	COG0405	Gamma-glutamyltransferase
IC780_04445	COG2826	transposase and inactivated derivatives, IS30 family
IC780_04475	COG3586	endonuclease activity
IC780_04480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC780_04505	COG2826	transposase and inactivated derivatives, IS30 family
IC780_04525	COG0477	Major facilitator Superfamily
IC780_04530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC780_04550	COG0531	amino acid
IC780_04555	COG2040	homocysteine
IC780_04580	COG1309	transcriptional regulator
IC780_04585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC780_04590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC780_04600	COG1607	acyl-coa hydrolase
IC780_04610	COG0523	cobalamin synthesis protein
IC780_04620	COG4681	YaeQ
IC780_04630	COG0726	polysaccharide deacetylase
IC780_04630	COG1649	PFAM Uncharacterised BCR, COG1649
IC780_04635	COG1215	transferase activity, transferring glycosyl groups
IC780_04645	COG1024	Enoyl-CoA hydratase
IC780_04675	COG1414	Transcriptional regulator
IC780_04710	COG2271	Major facilitator Superfamily
IC780_04720	COG2267	carboxylic ester hydrolase activity
IC780_04725	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_04740	COG0028	Belongs to the TPP enzyme family
IC780_04755	COG0242	peptide deformylase activity
IC780_04760	COG2066	Belongs to the glutaminase family
IC780_04765	COG2207	Transcriptional regulator
IC780_04770	COG2223	nitrite transmembrane transporter activity
IC780_04805	COG0306	phosphate transporter
IC780_04825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC780_04870	COG4181	ATPase activity
IC780_04875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC780_04900	COG0583	DNA-binding transcription factor activity
IC780_04910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_04915	COG1773	rubredoxin
IC780_04965	COG2851	Citrate transporter
IC780_04970	COG1253	flavin adenine dinucleotide binding
IC780_05010	COG0804	urea catabolic process
IC780_05020	COG0830	nickel cation binding
IC780_05040	COG0742	ribosomal rna small subunit methyltransferase
IC780_05045	COG0768	penicillin binding
IC780_05070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC780_05075	COG2878	Part of a membrane complex involved in electron transport
IC780_05080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC780_05090	COG3384	dioxygenase
IC780_05130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC780_05160	COG1674	ftsk spoiiie
IC780_05490	COG0006	proline dipeptidase activity
IC780_05495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_05500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_05525	COG0583	DNA-binding transcription factor activity
IC780_05570	COG1388	LysM domain
IC780_05570	COG0741	lytic transglycosylase activity
IC780_05580	COG4174	ABC transporter (Permease)
IC780_05585	COG4239	(ABC) transporter, permease
IC780_05590	COG4172	Belongs to the ABC transporter superfamily
IC780_05615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC780_05625	COG5001	Diguanylate cyclase
IC780_05625	COG4251	negative regulation of phosphorylation
IC780_05625	COG3706	GGDEF domain
IC780_05625	COG2203	Gaf domain
IC780_05635	COG1902	pentaerythritol trinitrate reductase activity
IC780_05635	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC780_05650	COG0251	oxidation-reduction process
IC780_05660	COG0583	DNA-binding transcription factor activity
IC780_05680	COG4269	membrane
IC780_05730	COG1846	Transcriptional regulator
IC780_05780	COG1113	amino acid transport
IC780_05790	COG0531	amino acid
IC780_05810	COG1012	belongs to the aldehyde dehydrogenase family
IC780_05830	COG1113	amino acid transport
IC780_05850	COG0697	spore germination
IC780_05870	COG1960	acyl-CoA dehydrogenase activity
IC780_05880	COG1012	belongs to the aldehyde dehydrogenase family
IC780_05885	COG1024	Enoyl-CoA hydratase
IC780_05890	COG2814	Major facilitator Superfamily
IC780_05905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_05925	COG1944	ATP diphosphatase activity
IC780_05955	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC780_05970	COG0583	DNA-binding transcription factor activity
IC780_05975	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC780_05980	COG2072	flavoprotein involved in K transport
IC780_05995	COG1309	transcriptional regulator
IC780_06000	COG1741	Belongs to the pirin family
IC780_06015	COG2072	flavoprotein involved in K transport
IC780_06025	COG2252	PERMEase
IC780_06030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC780_06035	COG3038	cytochrome b561
IC780_06045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC780_06055	COG0527	aspartate kinase activity
IC780_06065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC780_06080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC780_06095	COG0667	Aldo Keto reductase
IC780_06105	COG1765	OsmC-like protein
IC780_06165	COG0625	glutathione transferase activity
IC780_06170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC780_06190	COG3634	alkyl hydroperoxide reductase activity
IC780_06210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_06225	COG1643	Atp-dependent helicase
IC780_06245	COG2814	Major facilitator Superfamily
IC780_06250	COG3135	benzoate transporter
IC780_06255	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_06260	COG0633	Ferredoxin
IC780_06260	COG0543	2 iron, 2 sulfur cluster binding
IC780_06265	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC780_06270	COG4638	Rieske (2fe-2S)
IC780_06280	COG0583	DNA-binding transcription factor activity
IC780_06290	COG2871	sodium ion transport
IC780_06375	COG1570	exodeoxyribonuclease VII activity
IC780_06410	COG1280	lysine exporter protein (LysE YggA)
IC780_06415	COG1278	Cold shock
IC780_06445	COG2814	Major facilitator Superfamily
IC780_06455	COG0667	Aldo Keto reductase
IC780_06475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC780_06475	COG0517	IMP dehydrogenase activity
IC780_06480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC780_06490	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC780_06495	COG1137	ATPase activity
IC780_06500	COG1538	Outer membrane efflux protein
IC780_06530	COG4122	O-methyltransferase activity
IC780_06540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC780_06585	COG1560	Kdo2-lipid A biosynthetic process
IC780_06605	COG1469	GTP cyclohydrolase I activity
IC780_06615	COG1294	oxidase, subunit
IC780_06620	COG1271	oxidase subunit
IC780_06630	COG0583	DNA-binding transcription factor activity
IC780_06635	COG0402	S-adenosylhomocysteine deaminase activity
IC780_06650	COG2814	Major facilitator Superfamily
IC780_06670	COG4774	siderophore transport
IC780_06675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC780_06685	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_06695	COG1522	sequence-specific DNA binding
IC780_06700	COG0626	cystathionine gamma-synthase activity
IC780_06710	COG1278	Cold shock
IC780_06715	COG1309	transcriptional regulator
IC780_06795	COG3209	COG3209 Rhs family protein
IC780_06840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC780_06845	COG3713	MltA-interacting MipA family protein
IC780_06860	COG2076	Multidrug Resistance protein
IC780_06875	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_06890	COG3220	belongs to the UPF0276 family
IC780_06900	COG1595	DNA-templated transcription, initiation
IC780_06910	COG0583	DNA-binding transcription factor activity
IC780_06915	COG1914	H( )-stimulated, divalent metal cation uptake system
IC780_06935	COG4770	biotin carboxylase activity
IC780_06940	COG0038	chloride channel
IC780_06985	COG1063	alcohol dehydrogenase
IC780_07000	COG0439	Biotin carboxylase
IC780_07005	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_07010	COG1733	regulation of RNA biosynthetic process
IC780_07025	COG0864	Transcriptional regulator
IC780_07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC780_07040	COG1116	anion transmembrane transporter activity
IC780_07065	COG0477	Major facilitator Superfamily
IC780_07170	COG0590	tRNA wobble adenosine to inosine editing
IC780_07175	COG2807	transmembrane transport
IC780_07190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_07195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC780_07205	COG0789	Transcriptional regulator
IC780_07215	COG1760	l-serine dehydratase
IC780_07220	COG2030	dehydratase
IC780_07220	COG1012	belongs to the aldehyde dehydrogenase family
IC780_07225	COG3396	Phenylacetate-CoA oxygenase
IC780_07230	COG3460	Phenylacetate-CoA oxygenase
IC780_07235	COG3396	Phenylacetate-CoA oxygenase
IC780_07240	COG2151	metal-sulfur cluster biosynthetic enzyme
IC780_07245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_07250	COG1024	Enoyl-CoA hydratase
IC780_07255	COG1024	Enoyl-CoA hydratase
IC780_07260	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_07270	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC780_07275	COG3327	negative regulation of DNA-templated transcription, initiation
IC780_07285	COG2050	protein possibly involved in aromatic compounds catabolism
IC780_07295	COG0406	alpha-ribazole phosphatase activity
IC780_07315	COG3179	chitinase
IC780_07365	COG1309	transcriptional regulator
IC780_07370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC780_07385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC780_07390	COG0531	amino acid
IC780_07395	COG0753	catalase activity
IC780_07400	COG3038	cytochrome b561
IC780_07415	COG0583	DNA-binding transcription factor activity
IC780_07425	COG1414	Transcriptional regulator
IC780_07430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_07445	COG1840	ABC-type Fe3 transport system, periplasmic component
IC780_07450	COG3842	ATPase activity
IC780_07465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC780_07470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC780_07475	COG2814	Major facilitator Superfamily
IC780_07480	COG1960	acyl-CoA dehydrogenase activity
IC780_07485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC780_07495	COG1024	Enoyl-CoA hydratase
IC780_07510	COG2814	Major facilitator Superfamily
IC780_07520	COG0183	Belongs to the thiolase family
IC780_07525	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_07530	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_07535	COG1024	Enoyl-CoA hydratase
IC780_07540	COG1960	acyl-CoA dehydrogenase activity
IC780_07560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC780_07565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC780_07575	COG2814	Major facilitator Superfamily
IC780_07585	COG1960	acyl-CoA dehydrogenase activity
IC780_07600	COG0583	DNA-binding transcription factor activity
IC780_07610	COG4770	biotin carboxylase activity
IC780_07615	COG1024	Enoyl-CoA hydratase
IC780_07620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC780_07625	COG1960	acyl-CoA dehydrogenase activity
IC780_07630	COG1309	transcriptional regulator
IC780_07635	COG0318	PFAM AMP-dependent synthetase and ligase
IC780_07655	COG0583	DNA-binding transcription factor activity
IC780_07700	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_07720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC780_07740	COG2205	protein histidine kinase activity
IC780_07740	COG0784	Response regulator, receiver
IC780_07780	COG0765	amino acid transport
IC780_07785	COG0765	amino acid transport
IC780_07795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC780_07800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC780_07810	COG1280	lysine exporter protein (LysE YggA)
IC780_07815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC780_07825	COG1045	serine acetyltransferase
IC780_07840	COG0583	DNA-binding transcription factor activity
IC780_07845	COG0625	glutathione transferase activity
IC780_07850	COG0625	glutathione transferase activity
IC780_07855	COG0583	DNA-binding transcription factor activity
IC780_07865	COG1346	cytolysis
IC780_07890	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC780_07895	COG3052	prosthetic group binding
IC780_07915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC780_07935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_07945	COG1294	oxidase, subunit
IC780_07950	COG1271	oxidase subunit
IC780_07970	COG0477	Major facilitator Superfamily
IC780_07980	COG4521	taurine ABC transporter
IC780_07985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC780_07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_07995	COG2175	clavaminate synthase activity
IC780_08005	COG1953	Uracil, thiamine, allantoin
IC780_08015	COG0583	DNA-binding transcription factor activity
IC780_08025	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC780_08040	COG0640	Transcriptional regulator
IC780_08045	COG0798	PFAM Bile acid sodium symporter
IC780_08050	COG0431	NADPH-dependent FMN reductase
IC780_08055	COG0583	DNA-binding transcription factor activity
IC780_08070	COG3634	alkyl hydroperoxide reductase activity
IC780_08105	COG1301	dicarboxylic acid transport
IC780_08110	COG0436	Aminotransferase
IC780_08120	COG0386	Belongs to the glutathione peroxidase family
IC780_08125	COG1917	Cupin 2, conserved barrel domain protein
IC780_08125	COG2207	Transcriptional regulator
IC780_08160	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC780_08185	COG0012	GTP binding
IC780_08190	COG2011	ABC-type metal ion transport system permease component
IC780_08195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC780_08205	COG1464	Belongs to the NlpA lipoprotein family
IC780_08235	COG0765	amino acid transport
IC780_08240	COG0765	amino acid transport
IC780_08245	COG1126	abc transporter atp-binding protein
IC780_08255	COG1522	sequence-specific DNA binding
IC780_08280	COG2197	response regulator
IC780_08300	COG0583	DNA-binding transcription factor activity
IC780_08310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC780_08320	COG0697	spore germination
IC780_08340	COG3121	Chaperone
IC780_08345	COG3539	Fimbrial protein
IC780_08370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC780_08370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC780_08410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC780_08425	COG2353	YceI-like domain
IC780_08435	COG3698	Phosphodiester glycosidase
IC780_08450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC780_08455	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC780_08455	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC780_08455	COG0506	proline dehydrogenase activity
IC780_08465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC780_08470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC780_08490	COG1132	(ABC) transporter
IC780_08495	COG3122	Protein conserved in bacteria
IC780_08500	COG3619	membrane
IC780_08520	COG2850	peptidyl-arginine hydroxylation
IC780_08525	COG0424	maF-like protein
IC780_08565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC780_08575	COG1192	Involved in chromosome partitioning
IC780_08580	COG1475	DNA binding
IC780_08585	COG0811	peptide transport
IC780_08595	COG1132	(ABC) transporter
IC780_08620	COG0084	hydrolase, TatD family'
IC780_08685	COG0776	regulation of translation
IC780_08700	COG2431	L-lysine efflux transmembrane transporter activity
IC780_08715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC780_08765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC780_08780	COG0305	Participates in initiation and elongation during chromosome replication
IC780_08860	COG4695	Portal protein
IC780_08980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC780_09005	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC780_09030	COG0601	transmembrane transport
IC780_09035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC780_09040	COG4172	Belongs to the ABC transporter superfamily
IC780_09070	COG0702	epimerase
IC780_09075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC780_09095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC780_09125	COG0316	Belongs to the HesB IscA family
IC780_09130	COG0822	iron-sulfur transferase activity
IC780_09155	COG0776	regulation of translation
IC780_09160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC780_09165	COG2207	Transcriptional regulator
IC780_09170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_09175	COG1960	acyl-CoA dehydrogenase activity
IC780_09180	COG1960	acyl-CoA dehydrogenase activity
IC780_09195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC780_09200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC780_09215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC780_09220	COG0406	alpha-ribazole phosphatase activity
IC780_09235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC780_09240	COG0730	response to heat
IC780_09265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC780_09280	COG1131	(ABC) transporter
IC780_09285	COG0842	Transport permease protein
IC780_09290	COG0842	Transport permease protein
IC780_09340	COG2226	methyltransferase
IC780_09365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC780_09400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC780_09410	COG0133	tryptophan synthase activity
IC780_09425	COG3706	GGDEF domain
IC780_09440	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC780_09445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC780_09450	COG0022	dehydrogenase e1 component
IC780_09455	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_09460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_09470	COG1063	alcohol dehydrogenase
IC780_09475	COG3781	membrane
IC780_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_09485	COG3453	Protein conserved in bacteria
IC780_09495	COG0730	response to heat
IC780_09510	COG2207	Transcriptional regulator
IC780_09510	COG3708	Transcriptional regulator
IC780_09520	COG0477	Major facilitator Superfamily
IC780_09530	COG1027	Aspartate ammonia-lyase
IC780_09545	COG0583	DNA-binding transcription factor activity
IC780_09550	COG0583	DNA-binding transcription factor activity
IC780_09555	COG0183	Belongs to the thiolase family
IC780_09560	COG2031	fatty acid transporter
IC780_09575	COG0583	DNA-binding transcription factor activity
IC780_09600	COG2814	Major facilitator Superfamily
IC780_09630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_09635	COG2610	gluconate transmembrane transporter activity
IC780_09640	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_09645	COG2207	Transcriptional regulator
IC780_09665	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_09675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_09690	COG0543	2 iron, 2 sulfur cluster binding
IC780_09690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_09695	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC780_09700	COG4638	Rieske (2fe-2S)
IC780_09710	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC780_09715	COG4149	molybdate abc transporter
IC780_09720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC780_09745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC780_09750	COG3251	PFAM MbtH domain protein
IC780_09760	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_09765	COG1169	isochorismate synthase
IC780_09770	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC780_09775	COG1535	isochorismatase
IC780_09775	COG3433	isochorismatase activity
IC780_09780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_09785	COG4771	TonB-dependent receptor
IC780_09845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_09850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_09855	COG0745	RESPONSE REGULATOR receiver
IC780_09860	COG2205	protein histidine kinase activity
IC780_09870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC780_09875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC780_09885	COG0753	catalase activity
IC780_09895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC780_09920	COG3539	Fimbrial protein
IC780_09950	COG0601	transmembrane transport
IC780_09955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC780_09975	COG1132	(ABC) transporter
IC780_09980	COG1132	(ABC) transporter
IC780_10000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_10010	COG0805	protein transport
IC780_10015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC780_10030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_10035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_10040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_10045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_10075	COG4771	TonB-dependent receptor
IC780_10080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_10085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_10115	COG2175	clavaminate synthase activity
IC780_10130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_10135	COG0667	Aldo Keto reductase
IC780_10150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC780_10155	COG2175	clavaminate synthase activity
IC780_10275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC780_10295	COG1120	ATPase activity
IC780_10300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC780_10330	COG1566	PFAM secretion protein HlyD family protein
IC780_10340	COG2271	Major facilitator Superfamily
IC780_10355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_10370	COG2188	Transcriptional regulator
IC780_10450	COG1309	transcriptional regulator
IC780_10475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC780_10505	COG0583	DNA-binding transcription factor activity
IC780_10510	COG4948	Mandelate Racemase Muconate Lactonizing
IC780_10515	COG4829	muconolactone delta-isomerase
IC780_10525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC780_10530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC780_10535	COG0183	Belongs to the thiolase family
IC780_10540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC780_10545	COG1012	belongs to the aldehyde dehydrogenase family
IC780_10560	COG3733	amine oxidase
IC780_10570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_10580	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_10590	COG4638	Rieske (2fe-2S)
IC780_10610	COG0154	amidase activity
IC780_10620	COG2814	Major facilitator Superfamily
IC780_10645	COG1960	acyl-CoA dehydrogenase activity
IC780_10650	COG0583	DNA-binding transcription factor activity
IC780_10655	COG1414	Transcriptional regulator
IC780_10670	COG2391	methyltransferase activity
IC780_10680	COG4993	Dehydrogenase
IC780_10685	COG3659	wide pore channel activity
IC780_10690	COG3420	alginic acid biosynthetic process
IC780_10700	COG3485	protocatechuate 3,4-dioxygenase
IC780_10705	COG3485	protocatechuate 3,4-dioxygenase
IC780_10710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC780_10715	COG2271	Major facilitator Superfamily
IC780_10720	COG0596	Alpha beta hydrolase
IC780_10725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC780_10730	COG0183	Belongs to the thiolase family
IC780_10735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC780_10740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC780_10750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC780_10760	COG2323	membrane
IC780_10765	COG0148	phosphopyruvate hydratase activity
IC780_10805	COG1902	pentaerythritol trinitrate reductase activity
IC780_10805	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC780_10830	COG0542	response to heat
IC780_10835	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC780_10865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC780_10870	COG0569	domain protein
IC780_10875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC780_10890	COG4774	siderophore transport
IC780_10895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC780_10905	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC780_10920	COG1294	oxidase, subunit
IC780_10925	COG4890	Cyd operon protein YbgT
IC780_10950	COG0552	protein localization to endoplasmic reticulum
IC780_10975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC780_10980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC780_10985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC780_10995	COG0583	DNA-binding transcription factor activity
IC780_11000	COG0024	Methionine aminopeptidase
IC780_11030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC780_11030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC780_11035	COG1105	Belongs to the carbohydrate kinase PfkB family
IC780_11040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC780_11040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC780_11040	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC780_11075	COG0659	secondary active sulfate transmembrane transporter activity
IC780_11090	COG1113	amino acid transport
IC780_11100	COG1522	sequence-specific DNA binding
IC780_11115	COG1011	Hydrolase
IC780_11120	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC780_11130	COG2137	regulation of response to DNA damage stimulus
IC780_11145	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC780_11165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC780_11180	COG0575	Belongs to the CDS family
IC780_11185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC780_11210	COG3852	Histidine kinase
IC780_11215	COG2204	response regulator
IC780_11270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC780_11275	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC780_11295	COG0697	spore germination
IC780_11310	COG0303	'Molybdopterin
IC780_11315	COG0315	cyclic pyranopterin monophosphate synthase activity
IC780_11315	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC780_11330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC780_11335	COG0243	molybdopterin cofactor binding
IC780_11345	COG0243	molybdopterin cofactor binding
IC780_11350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_11355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_11355	COG2146	nitrite reductase [NAD(P)H] activity
IC780_11365	COG0745	RESPONSE REGULATOR receiver
IC780_11370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_11370	COG1116	anion transmembrane transporter activity
IC780_11390	COG0511	ligase activity, forming carbon-carbon bonds
IC780_11450	COG0069	glutamate synthase activity
IC780_11480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC780_11495	COG1335	isochorismatase
IC780_11505	COG1454	alcohol dehydrogenase
IC780_11510	COG0824	Thioesterase
IC780_11525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC780_11550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC780_11555	COG2030	dehydratase
IC780_11560	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_11565	COG0183	Belongs to the thiolase family
IC780_11575	COG0583	DNA-binding transcription factor activity
IC780_11580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC780_11590	COG1522	sequence-specific DNA binding
IC780_11595	COG3135	benzoate transporter
IC780_11620	COG0589	response to stress
IC780_11625	COG0488	(ABC) transporter
IC780_11670	COG0668	transmembrane transport
IC780_11680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC780_11685	COG2423	ornithine cyclodeaminase activity
IC780_11690	COG4264	IucA IucC family
IC780_11700	COG4264	IucA IucC family
IC780_11745	COG1605	Chorismate mutase
IC780_11760	COG0625	glutathione transferase activity
IC780_11790	COG0308	aminopeptidase N
IC780_11810	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC780_11820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC780_11825	COG1454	alcohol dehydrogenase
IC780_11845	COG0531	amino acid
IC780_11850	COG4303	Ethanolamine ammonia lyase large subunit
IC780_11855	COG4302	ethanolamine ammonia-lyase activity
IC780_11860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC780_11860	COG0519	Catalyzes the synthesis of GMP from XMP
IC780_11865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC780_11890	COG0697	spore germination
IC780_11895	COG1923	regulation of RNA biosynthetic process
IC780_11905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC780_11910	COG0802	atpase or kinase
IC780_11930	COG1187	pseudouridine synthase activity
IC780_11945	COG0583	DNA-binding transcription factor activity
IC780_11955	COG2814	Major facilitator Superfamily
IC780_11960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC780_11990	COG0729	surface antigen
IC780_12010	COG0174	glutamine synthetase
IC780_12015	COG0745	RESPONSE REGULATOR receiver
IC780_12020	COG2205	protein histidine kinase activity
IC780_12025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC780_12030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC780_12035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC780_12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_12065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC780_12070	COG1960	acyl-CoA dehydrogenase activity
IC780_12085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC780_12090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC780_12095	COG2890	protein-(glutamine-N5) methyltransferase activity
IC780_12115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_12125	COG3658	cytochrome
IC780_12130	COG1215	transferase activity, transferring glycosyl groups
IC780_12135	COG1649	PFAM Uncharacterised BCR, COG1649
IC780_12135	COG0726	polysaccharide deacetylase
IC780_12165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC780_12175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC780_12200	COG0305	Participates in initiation and elongation during chromosome replication
IC780_12205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC780_12215	COG1305	Transglutaminase-like
IC780_12225	COG2308	Evidence 4 Homologs of previously reported genes of
IC780_12255	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC780_12260	COG0138	bifunctional purine biosynthesis protein purh
IC780_12265	COG0151	Belongs to the GarS family
IC780_12270	COG1464	Belongs to the NlpA lipoprotein family
IC780_12275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC780_12280	COG2011	ABC-type metal ion transport system permease component
IC780_12295	COG1301	dicarboxylic acid transport
IC780_12340	COG2855	membrane
IC780_12355	COG2814	Major facilitator Superfamily
IC780_12360	COG3246	L-lysine catabolic process to acetate
IC780_12365	COG2175	clavaminate synthase activity
IC780_12390	COG0745	RESPONSE REGULATOR receiver
IC780_12395	COG0642	Histidine kinase
IC780_12400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC780_12410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC780_12435	COG5002	protein histidine kinase activity
IC780_12450	COG2351	hydroxyisourate hydrolase activity
IC780_12460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC780_12460	COG3008	intermembrane lipid transfer
IC780_12465	COG2995	paraquat-inducible protein a
IC780_12495	COG2985	domain, Protein
IC780_12510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC780_12510	COG2169	Transcriptional regulator
IC780_12520	COG1309	transcriptional regulator
IC780_12605	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_12610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC780_12610	COG0475	glutathione-regulated potassium exporter activity
IC780_12615	COG0786	glutamate:sodium symporter activity
IC780_12625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC780_12635	COG0596	Alpha beta hydrolase
IC780_12655	COG0583	DNA-binding transcription factor activity
IC780_12660	COG1335	isochorismatase
IC780_12765	COG0515	serine threonine protein kinase
IC780_12765	COG2815	serine threonine protein kinase
IC780_12795	COG1610	YqeY-like protein
IC780_12855	COG0778	Nitroreductase
IC780_12865	COG0513	Belongs to the DEAD box helicase family
IC780_12885	COG2363	Small membrane protein
IC780_12910	COG4650	regulator
IC780_12915	COG1234	tRNA 3'-trailer cleavage
IC780_12920	COG1690	Belongs to the RtcB family
IC780_12940	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC780_12945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC780_12955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC780_12975	COG1960	acyl-CoA dehydrogenase activity
IC780_12980	COG1301	dicarboxylic acid transport
IC780_12990	COG3139	Protein of unknown function (DUF1315)
IC780_12995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC780_13000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC780_13020	COG0642	Histidine kinase
IC780_13035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC780_13045	COG1720	tRNA m6t6A37 methyltransferase activity
IC780_13055	COG0384	phenazine biosynthesis protein PhzF
IC780_13060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC780_13065	COG0826	peptidase U32
IC780_13070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC780_13080	COG4598	ABC transporter
IC780_13085	COG4160	amino acid transport
IC780_13090	COG4215	(ABC) transporter
IC780_13105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_13145	COG1131	(ABC) transporter
IC780_13150	COG0842	Transport permease protein
IC780_13165	COG0772	Belongs to the SEDS family
IC780_13170	COG2951	lytic endotransglycosylase activity
IC780_13195	COG2207	Transcriptional regulator
IC780_13210	COG0052	Belongs to the universal ribosomal protein uS2 family
IC780_13215	COG0024	Methionine aminopeptidase
IC780_13225	COG2223	nitrite transmembrane transporter activity
IC780_13235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_13240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC780_13245	COG1960	acyl-CoA dehydrogenase activity
IC780_13260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC780_13265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC780_13270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC780_13290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC780_13295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC780_13300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC780_13335	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC780_13345	COG0174	glutamine synthetase
IC780_13360	COG0512	Glutamine amidotransferase of anthranilate synthase
IC780_13375	COG2840	Smr protein MutS2
IC780_13385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC780_13395	COG0302	gtp cyclohydrolase
IC780_13415	COG3739	integral membrane protein
IC780_13430	COG1741	Belongs to the pirin family
IC780_13440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC780_13445	COG2826	transposase and inactivated derivatives, IS30 family
IC780_13455	COG2964	Protein conserved in bacteria
IC780_13465	COG2423	ornithine cyclodeaminase activity
IC780_13470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC780_13510	COG2814	Major facilitator Superfamily
IC780_13540	COG2879	small protein
IC780_13545	COG1966	Carbon starvation protein
IC780_13550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC780_13565	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC780_13590	COG1067	ATP-dependent peptidase activity
IC780_13595	COG0583	DNA-binding transcription factor activity
IC780_13620	COG1686	Belongs to the peptidase S11 family
IC780_13625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC780_13650	COG3647	Membrane
IC780_13665	COG0616	signal peptide processing
IC780_13670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC780_13680	COG0573	inorganic phosphate transmembrane transporter activity
IC780_13685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC780_13690	COG1113	amino acid transport
IC780_13695	COG3961	Belongs to the TPP enzyme family
IC780_13700	COG1522	sequence-specific DNA binding
IC780_13710	COG0076	glutamate decarboxylase activity
IC780_13715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC780_13740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_13775	COG0352	thiamine-phosphate diphosphorylase activity
IC780_13810	COG0612	Peptidase, M16
IC780_13820	COG1823	symporter activity
IC780_13825	COG0583	DNA-binding transcription factor activity
IC780_13830	COG0477	Major facilitator Superfamily
IC780_13905	COG0739	heme binding
IC780_13905	COG0741	lytic transglycosylase activity
IC780_13905	COG1196	nuclear chromosome segregation
IC780_14015	COG3728	DNA packaging
IC780_14015	COG5484	DNA packaging
IC780_14205	COG1187	pseudouridine synthase activity
IC780_14220	COG1686	Belongs to the peptidase S11 family
IC780_14225	COG1252	NADH dehydrogenase
IC780_14235	COG0415	Belongs to the DNA photolyase family
IC780_14250	COG1215	transferase activity, transferring glycosyl groups
IC780_14265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC780_14280	COG2070	2-Nitropropane dioxygenase
IC780_14335	COG0556	nucleotide-excision repair
IC780_14340	COG3706	GGDEF domain
IC780_14360	COG0436	Aminotransferase
IC780_14385	COG4221	oxidoreductase activity
IC780_14395	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC780_14400	COG1381	Involved in DNA repair and RecF pathway recombination
IC780_14410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC780_14425	COG0681	Belongs to the peptidase S26 family
IC780_14430	COG0481	GTPase activity
IC780_14440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC780_14460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC780_14465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC780_14470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC780_14480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC780_14485	COG4208	sulfate ABC transporter
IC780_14490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC780_14495	COG0583	DNA-binding transcription factor activity
IC780_14500	COG4625	pathogenesis
IC780_14510	COG0602	queuosine metabolic process
IC780_14515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC780_14530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC780_14545	COG1051	belongs to the nudix hydrolase family
IC780_14545	COG1056	cytidyltransferase-related domain
IC780_14550	COG1024	Enoyl-CoA hydratase
IC780_14555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC780_14570	COG2814	Major facilitator Superfamily
IC780_14575	COG0047	phosphoribosylformylglycinamidine synthase activity
IC780_14575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC780_14600	COG1473	amidohydrolase
IC780_14605	COG0824	Thioesterase
IC780_14625	COG0823	Involved in the tonB-independent uptake of proteins
IC780_14645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC780_14680	COG0628	permease
IC780_14690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC780_14695	COG0596	Alpha beta hydrolase
IC780_14700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC780_14700	COG0616	signal peptide processing
IC780_14710	COG0658	competence protein
IC780_14710	COG2333	competence protein COMEC
IC780_14715	COG1136	(ABC) transporter
IC780_14720	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC780_14755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_14775	COG0463	Glycosyl transferase, family 2
IC780_14785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC780_14795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_14815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC780_14820	COG1280	lysine exporter protein (LysE YggA)
IC780_14835	COG0019	diaminopimelate decarboxylase activity
IC780_14845	COG1113	amino acid transport
IC780_14850	COG1115	amino acid carrier protein
IC780_14975	COG0681	Belongs to the peptidase S26 family
IC780_15010	COG4373	Mu-like prophage FluMu protein gp28
IC780_15020	COG4383	Mu-like prophage protein gp29
IC780_15025	COG2369	cell adhesion
IC780_15045	COG4397	Mu-like prophage major head subunit gpT
IC780_15135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC780_15140	COG0243	molybdopterin cofactor binding
IC780_15145	COG1929	Belongs to the glycerate kinase type-1 family
IC780_15160	COG0778	Nitroreductase
IC780_15165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_15170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_15190	COG1012	belongs to the aldehyde dehydrogenase family
IC780_15195	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC780_15200	COG0583	DNA-binding transcription factor activity
IC780_15205	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_15210	COG0596	Alpha beta hydrolase
IC780_15215	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_15215	COG0596	Alpha beta hydrolase
IC780_15220	COG0596	Alpha beta hydrolase
IC780_15220	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_15225	COG1902	pentaerythritol trinitrate reductase activity
IC780_15230	COG1309	transcriptional regulator
IC780_15290	COG3811	Belongs to the UPF0386 family
IC780_15310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC780_15325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_15330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_15350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC780_15355	COG0183	Belongs to the thiolase family
IC780_15360	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_15365	COG1024	Enoyl-CoA hydratase
IC780_15370	COG1960	acyl-CoA dehydrogenase activity
IC780_15375	COG0644	oxidoreductase
IC780_15375	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC780_15435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC780_15460	COG1002	Type II restriction enzyme, methylase subunits
IC780_15465	COG1061	Type III restriction enzyme res subunit
IC780_15475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC780_15490	COG4372	Transposase
IC780_15535	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IC780_15555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC780_15580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC780_15600	COG0741	lytic transglycosylase activity
IC780_15620	COG0584	glycerophosphoryl diester phosphodiesterase
IC780_15625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC780_15650	COG1597	lipid kinase activity
IC780_15665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC780_15670	COG0477	Major facilitator Superfamily
IC780_15720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC780_15725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC780_15750	COG0505	Belongs to the CarA family
IC780_15770	COG0589	response to stress
IC780_15790	COG2321	neutral zinc metallopeptidase
IC780_15795	COG2354	Protein conserved in bacteria
IC780_15815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_15840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC780_15845	COG1053	succinate dehydrogenase
IC780_15850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC780_15855	COG2009	succinate dehydrogenase
IC780_15890	COG2921	Belongs to the UPF0250 family
IC780_15895	COG0321	lipoyl(octanoyl) transferase activity
IC780_15910	COG0531	amino acid
IC780_15920	COG1733	regulation of RNA biosynthetic process
IC780_15925	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC780_15930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC780_15930	COG1648	precorrin-2 dehydrogenase activity
IC780_15945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC780_15975	COG0671	phosphoesterase, PA-phosphatase related
IC780_15980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_15990	COG1538	Outer membrane efflux protein
IC780_15995	COG0393	Putative heavy-metal-binding
IC780_16000	COG0393	Putative heavy-metal-binding
IC780_16010	COG1028	Short-chain dehydrogenase reductase Sdr
IC780_16020	COG0525	valine-tRNA ligase activity
IC780_16030	COG0525	valine-tRNA ligase activity
IC780_16050	COG0583	DNA-binding transcription factor activity
IC780_16055	COG0004	ammonium transporteR
IC780_16065	COG0642	Histidine kinase
IC780_16070	COG0745	RESPONSE REGULATOR receiver
IC780_16075	COG2194	sulfuric ester hydrolase activity
IC780_16095	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC780_16110	COG2315	Protein conserved in bacteria
IC780_16115	COG0142	geranyltranstransferase activity
IC780_16120	COG2828	Protein conserved in bacteria
IC780_16125	COG1113	amino acid transport
IC780_16130	COG2816	NAD+ diphosphatase activity
IC780_16135	COG3046	protein related to deoxyribodipyrimidine photolyase
IC780_16165	COG2207	Transcriptional regulator
IC780_16190	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_16210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC780_16220	COG1530	ribonuclease E activity
IC780_16225	COG0424	maF-like protein
IC780_16230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC780_16235	COG1792	Involved in formation and maintenance of cell shape
IC780_16240	COG1077	Cell shape determining protein MreB Mrl
IC780_16245	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC780_16255	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC780_16285	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC780_16290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC780_16295	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC780_16300	COG1115	amino acid carrier protein
IC780_16320	COG2814	Major facilitator Superfamily
IC780_16325	COG1289	transmembrane transporter activity
IC780_16375	COG1376	ErfK ybiS ycfS ynhG family protein
IC780_16380	COG2832	Protein of unknown function (DUF454)
IC780_16405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC780_16420	COG0840	transmembrane signaling receptor activity
IC780_16460	COG3422	double-strand break repair
IC780_16465	COG2824	Alkylphosphonate utilization operon protein PhnA
IC780_16470	COG3189	MarR family transcriptional regulator
IC780_16475	COG0596	Alpha beta hydrolase
IC780_16485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC780_16490	COG1335	isochorismatase
IC780_16495	COG0251	oxidation-reduction process
IC780_16500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_16505	COG2233	PERMEase
IC780_16520	COG0354	folic acid binding
IC780_16525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC780_16535	COG0679	Auxin Efflux Carrier
IC780_16540	COG1902	pentaerythritol trinitrate reductase activity
IC780_16545	COG4772	TonB-dependent receptor
IC780_16550	COG2094	Belongs to the DNA glycosylase MPG family
IC780_16575	COG1217	gtp-binding protein TYPA
IC780_16580	COG2233	PERMEase
IC780_16590	COG0833	amino acid
IC780_16595	COG1690	Belongs to the RtcB family
IC780_16605	COG2885	chlorophyll binding
IC780_16605	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC780_16615	COG0183	Belongs to the thiolase family
IC780_16630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC780_16650	COG2207	Transcriptional regulator
IC780_16655	COG0183	Belongs to the thiolase family
IC780_16675	COG2153	protein acetylation
IC780_16685	COG1272	protein, Hemolysin III
IC780_16690	COG0477	Major facilitator Superfamily
IC780_16705	COG0450	alkyl hydroperoxide reductase
IC780_16725	COG0285	dihydrofolate synthase activity
IC780_16775	COG4206	TonB-dependent receptor
IC780_16780	COG2096	Adenosyltransferase
IC780_16800	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC780_16810	COG0745	RESPONSE REGULATOR receiver
IC780_16815	COG2205	protein histidine kinase activity
IC780_16825	COG1960	acyl-CoA dehydrogenase activity
IC780_16830	COG1960	acyl-CoA dehydrogenase activity
IC780_16865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC780_16905	COG0438	transferase activity, transferring glycosyl groups
IC780_16910	COG0463	Glycosyl transferase, family 2
IC780_16915	COG0726	polysaccharide deacetylase
IC780_16925	COG2194	sulfuric ester hydrolase activity
IC780_16940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC780_16950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC780_16985	COG1862	Preprotein translocase
IC780_16995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC780_17000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC780_17010	COG3781	membrane
IC780_17015	COG0613	PHP domain protein
IC780_17025	COG2350	Protein conserved in bacteria
IC780_17060	COG1607	acyl-coa hydrolase
IC780_17085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC780_17120	COG2199	diguanylate cyclase activity
IC780_17130	COG1408	metallophosphoesterase
IC780_17135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC780_17145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC780_17165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC780_17170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC780_17175	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC780_17180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC780_17185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC780_17195	COG2969	positive regulation of protein catabolic process
IC780_17230	COG1024	Enoyl-CoA hydratase
IC780_17230	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC780_17235	COG1960	acyl-CoA dehydrogenase activity
IC780_17240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC780_17255	COG1309	transcriptional regulator
IC780_17260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC780_17325	COG1183	phosphatidylcholine synthase activity
IC780_17330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC780_17360	COG1196	nuclear chromosome segregation
IC780_17360	COG0739	heme binding
IC780_17360	COG0741	lytic transglycosylase activity
IC780_17370	COG1702	phosphate starvation-inducible protein PhoH
IC780_17405	COG1295	ribonuclease BN
IC780_17415	COG2169	Transcriptional regulator
IC780_17420	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC780_17465	COG0557	exoribonuclease II activity
IC780_17470	COG0339	signal peptide processing
IC780_17475	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC780_17505	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC780_17510	COG1960	acyl-CoA dehydrogenase activity
IC780_17560	COG1841	ribosomal large subunit assembly
IC780_17645	COG0088	Forms part of the polypeptide exit tunnel
IC780_17650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC780_17665	COG0626	cystathionine gamma-synthase activity
IC780_17670	COG0433	COG0433 Predicted ATPase
IC780_17675	COG1017	nitric oxide dioxygenase activity
IC780_17675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC780_17680	COG1959	2 iron, 2 sulfur cluster binding
IC780_17695	COG1301	dicarboxylic acid transport
IC780_17700	COG1946	Acyl-CoA thioesterase
IC780_17705	COG2937	Belongs to the GPAT DAPAT family
IC780_17720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC780_17725	COG1040	competence protein
IC780_17730	COG0494	nUDIX hydrolase
IC780_17740	COG0598	Magnesium transport protein CorA
IC780_17750	COG2854	intermembrane phospholipid transfer
IC780_17760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC780_17765	COG1127	ABC transporter
IC780_17770	COG0513	Belongs to the DEAD box helicase family
IC780_17790	COG0408	coproporphyrinogen oxidase activity
IC780_17805	COG1960	acyl-CoA dehydrogenase activity
IC780_17815	COG1983	PspC domain protein
IC780_17820	COG0517	IMP dehydrogenase activity
IC780_17845	COG0752	glycyl-tRNA synthetase alpha subunit
IC780_17865	COG0583	DNA-binding transcription factor activity
IC780_17870	COG1794	racemase activity, acting on amino acids and derivatives
IC780_17875	COG0583	DNA-binding transcription factor activity
IC780_17915	COG1012	belongs to the aldehyde dehydrogenase family
IC780_17925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC780_17930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC780_17935	COG0833	amino acid
IC780_17940	COG2826	transposase and inactivated derivatives, IS30 family
IC780_17970	COG1192	Involved in chromosome partitioning
IC780_17975	COG0628	permease
IC780_17985	COG1289	transmembrane transporter activity
IC780_18000	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_18005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC780_18015	COG0277	FAD linked oxidase domain protein
IC780_18020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC780_18025	COG5006	permease, DMT superfamily
IC780_18045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC780_18050	COG5380	lipid catabolic process
IC780_18060	COG0335	large ribosomal subunit rRNA binding
IC780_18070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC780_18085	COG4969	Belongs to the N-Me-Phe pilin family
IC780_18110	COG4969	Belongs to the N-Me-Phe pilin family
IC780_18125	COG0194	GDP metabolic process
IC780_18140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC780_18160	COG3307	-O-antigen
IC780_18170	COG4969	Belongs to the N-Me-Phe pilin family
IC780_18180	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC780_18185	COG1704	LemA family
IC780_18195	COG0493	'glutamate synthase
IC780_18200	COG0069	glutamate synthase activity
IC780_18200	COG0067	glutamate synthase
IC780_18200	COG0070	glutamate synthase
IC780_18250	COG2226	methyltransferase
IC780_18265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC780_18270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC780_18315	COG0833	amino acid
IC780_18390	COG0488	(ABC) transporter
IC780_18395	COG0028	Belongs to the TPP enzyme family
IC780_18405	COG4221	oxidoreductase activity
IC780_18410	COG0659	secondary active sulfate transmembrane transporter activity
IC780_18440	COG0427	acetyl-CoA hydrolase
IC780_18470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC780_18515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC780_18580	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC780_18585	COG1733	regulation of RNA biosynthetic process
IC780_18615	COG1733	regulation of RNA biosynthetic process
IC780_18635	COG0667	Aldo Keto reductase
IC780_18655	COG0583	DNA-binding transcription factor activity
IC780_18660	COG2814	Major facilitator Superfamily
IC780_18695	COG1335	isochorismatase
IC780_18705	COG1012	belongs to the aldehyde dehydrogenase family
IC780_18710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC780_18720	COG1113	amino acid transport
IC780_18730	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC780_18780	COG2814	Major facilitator Superfamily
IC780_18790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC780_18790	COG0352	thiamine-phosphate diphosphorylase activity
IC780_18790	COG0351	phosphomethylpyrimidine kinase
IC780_18800	COG4221	oxidoreductase activity
IC780_18820	COG1309	transcriptional regulator
IC780_18840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC780_18850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC780_18855	COG3162	membrane
IC780_18860	COG0784	Response regulator, receiver
IC780_18860	COG2198	Histidine kinase
IC780_18860	COG2205	protein histidine kinase activity
IC780_18885	COG1522	sequence-specific DNA binding
IC780_18890	COG1335	isochorismatase
IC780_18895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC780_18905	COG0668	transmembrane transport
IC780_18910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC780_18915	COG1519	Transferase
IC780_18920	COG1902	pentaerythritol trinitrate reductase activity
IC780_18940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC780_18965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC780_18965	COG0426	domain, Protein
IC780_18970	COG2119	membrane
IC780_18980	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC780_18990	COG4942	peptidase
IC780_19005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC780_19015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC780_19035	COG0189	ligase activity
IC780_19060	COG0708	Exodeoxyribonuclease III
IC780_19065	COG1393	Belongs to the ArsC family
IC780_19080	COG3706	GGDEF domain
IC780_19095	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC780_19095	COG0666	response to abiotic stimulus
IC780_19115	COG2351	hydroxyisourate hydrolase activity
IC780_19120	COG2233	PERMEase
IC780_19130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC780_19140	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC780_19150	COG3150	esterase
IC780_19190	COG1388	LysM domain
IC780_19190	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC780_19205	COG2918	glutathione biosynthetic process
IC780_19220	COG2733	membrane
IC780_19225	COG0436	Aminotransferase
IC780_19230	COG0534	Mate efflux family protein
IC780_19325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC780_19330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC780_19340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC780_19375	COG1280	lysine exporter protein (LysE YggA)
IC780_19380	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC780_19385	COG0546	phosphoglycolate phosphatase activity
IC780_19395	COG0010	Belongs to the arginase family
IC780_19425	COG2188	Transcriptional regulator
IC780_19435	COG0523	cobalamin synthesis protein
IC780_19445	COG1113	amino acid transport
IC780_19455	COG0625	glutathione transferase activity
IC780_19460	COG0346	lactoylglutathione lyase activity
IC780_19475	COG1683	Conserved Protein
IC780_19480	COG0534	Mate efflux family protein
IC780_19485	COG0385	Bile acid
IC780_19490	COG1335	isochorismatase
IC780_19495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC780_19515	COG2116	formate transmembrane transporter activity
IC780_19520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC780_19525	COG2133	pyrroloquinoline quinone binding
IC780_19530	COG2983	Belongs to the UPF0260 family
IC780_19535	COG5487	UPF0391 membrane protein
IC780_19550	COG1194	a g-specific adenine glycosylase
IC780_19565	COG2818	Glycosylase
IC780_19570	COG1064	alcohol dehydrogenase
IC780_19590	COG0583	DNA-binding transcription factor activity
IC780_19595	COG0656	L-ascorbic acid biosynthetic process
IC780_19600	COG2814	Major facilitator Superfamily
IC780_19635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC780_19650	COG2233	PERMEase
IC780_19690	COG0733	neurotransmitter:sodium symporter activity
IC780_19700	COG0625	glutathione transferase activity
IC780_19730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC780_19735	COG0657	acetylesterase activity
IC780_19785	COG2951	lytic endotransglycosylase activity
IC780_19790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC780_19805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC780_19815	COG0671	phosphoesterase, PA-phosphatase related
IC780_19820	COG0861	Integral membrane protein TerC family
IC780_19830	COG0754	glutathionylspermidine amidase activity
IC780_19840	COG0402	S-adenosylhomocysteine deaminase activity
IC780_19855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC780_19910	COG4372	Transposase
IC780_19935	COG0589	response to stress
IC780_19940	COG0659	secondary active sulfate transmembrane transporter activity
IC780_19970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC780_20075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC780_20150	COG2826	transposase and inactivated derivatives, IS30 family
IC780_20160	COG2826	transposase and inactivated derivatives, IS30 family
IC780_20260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC780_20310	COG1192	Involved in chromosome partitioning
IC780_20325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC780_20360	COG0739	heme binding
IC780_20540	COG0501	Belongs to the peptidase M48B family
IC780_20640	COG2217	Heavy metal translocating P-type atpase
IC780_20650	COG2205	protein histidine kinase activity
IC780_20665	COG2132	Multicopper oxidase
IC780_20690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC780_20730	COG0789	Transcriptional regulator
IC780_20880	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC780_20915	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC780_20920	COG0659	secondary active sulfate transmembrane transporter activity
IC780_20935	COG3328	transposase activity
IC780_20940	COG0583	DNA-binding transcription factor activity
IC780_20945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC780_20950	COG3321	synthase
IC780_20950	COG0604	alcohol dehydrogenase
IC780_20960	COG0697	spore germination
IC780_20965	COG0477	Major facilitator Superfamily
IC780_20995	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC780_21010	COG1979	alcohol dehydrogenase
IC780_21020	COG1902	pentaerythritol trinitrate reductase activity
IC780_21030	COG1309	transcriptional regulator
IC780_21035	COG2130	NADP-dependent
IC780_21050	COG0582	viral genome integration into host DNA
IC780_21095	COG0210	DNA helicase
IC780_21115	COG0210	DNA helicase
IC780_21175	COG1525	nuclease
IC780_21255	COG1475	DNA binding
IC780_21270	COG3853	Toxic anion resistance protein (TelA)
IC780_21450	COG0741	lytic transglycosylase activity
IC780_21485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process