locus-tag	class	description
IC764_00010	COG0592	DNA-directed DNA polymerase activity
IC764_00020	COG0187	DNA topoisomerase II activity
IC764_00030	COG0586	Pfam SNARE associated Golgi protein
IC764_00035	COG0488	(ABC) transporter
IC764_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC764_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC764_00100	COG0625	glutathione transferase activity
IC764_00110	COG0733	neurotransmitter:sodium symporter activity
IC764_00150	COG2233	PERMEase
IC764_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_00200	COG2814	Major facilitator Superfamily
IC764_00205	COG0656	L-ascorbic acid biosynthetic process
IC764_00210	COG0583	DNA-binding transcription factor activity
IC764_00230	COG1064	alcohol dehydrogenase
IC764_00235	COG2818	Glycosylase
IC764_00250	COG1194	a g-specific adenine glycosylase
IC764_00265	COG5487	UPF0391 membrane protein
IC764_00270	COG2983	Belongs to the UPF0260 family
IC764_00275	COG2133	pyrroloquinoline quinone binding
IC764_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC764_00285	COG2116	formate transmembrane transporter activity
IC764_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC764_00310	COG1335	isochorismatase
IC764_00315	COG0385	Bile acid
IC764_00320	COG0534	Mate efflux family protein
IC764_00325	COG1683	Conserved Protein
IC764_00340	COG0346	lactoylglutathione lyase activity
IC764_00345	COG0625	glutathione transferase activity
IC764_00355	COG1113	amino acid transport
IC764_00365	COG0523	cobalamin synthesis protein
IC764_00375	COG2188	Transcriptional regulator
IC764_00405	COG0010	Belongs to the arginase family
IC764_00415	COG0546	phosphoglycolate phosphatase activity
IC764_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC764_00425	COG1280	lysine exporter protein (LysE YggA)
IC764_00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC764_00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC764_00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC764_00565	COG0534	Mate efflux family protein
IC764_00570	COG0436	Aminotransferase
IC764_00575	COG2733	membrane
IC764_00590	COG2918	glutathione biosynthetic process
IC764_00605	COG1388	LysM domain
IC764_00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC764_00625	COG4372	Transposase
IC764_00670	COG3150	esterase
IC764_00680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC764_00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC764_00700	COG2233	PERMEase
IC764_00705	COG2351	hydroxyisourate hydrolase activity
IC764_00725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC764_00725	COG0666	response to abiotic stimulus
IC764_00740	COG3706	GGDEF domain
IC764_00755	COG1393	Belongs to the ArsC family
IC764_00760	COG0708	Exodeoxyribonuclease III
IC764_00785	COG0189	ligase activity
IC764_00815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC764_00830	COG4942	peptidase
IC764_00840	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC764_00850	COG2119	membrane
IC764_00855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC764_00855	COG0426	domain, Protein
IC764_00880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC764_00900	COG1902	pentaerythritol trinitrate reductase activity
IC764_00905	COG1519	Transferase
IC764_00910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC764_00915	COG0668	transmembrane transport
IC764_00925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC764_00930	COG1335	isochorismatase
IC764_00935	COG1522	sequence-specific DNA binding
IC764_00960	COG2198	Histidine kinase
IC764_00960	COG2205	protein histidine kinase activity
IC764_00960	COG0784	Response regulator, receiver
IC764_00965	COG3162	membrane
IC764_00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC764_00980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC764_01000	COG1309	transcriptional regulator
IC764_01020	COG4221	oxidoreductase activity
IC764_01030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC764_01030	COG0351	phosphomethylpyrimidine kinase
IC764_01030	COG0352	thiamine-phosphate diphosphorylase activity
IC764_01040	COG2814	Major facilitator Superfamily
IC764_01055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC764_01065	COG1113	amino acid transport
IC764_01075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC764_01080	COG1012	belongs to the aldehyde dehydrogenase family
IC764_01090	COG1335	isochorismatase
IC764_01125	COG2814	Major facilitator Superfamily
IC764_01130	COG0583	DNA-binding transcription factor activity
IC764_01150	COG0667	Aldo Keto reductase
IC764_01170	COG1733	regulation of RNA biosynthetic process
IC764_01200	COG1733	regulation of RNA biosynthetic process
IC764_01205	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC764_01270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC764_01315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC764_01345	COG0427	acetyl-CoA hydrolase
IC764_01375	COG0659	secondary active sulfate transmembrane transporter activity
IC764_01380	COG4221	oxidoreductase activity
IC764_01390	COG0028	Belongs to the TPP enzyme family
IC764_01395	COG0488	(ABC) transporter
IC764_01470	COG0833	amino acid
IC764_01515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC764_01520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC764_01535	COG2226	methyltransferase
IC764_01585	COG0069	glutamate synthase activity
IC764_01585	COG0067	glutamate synthase
IC764_01585	COG0070	glutamate synthase
IC764_01590	COG0493	'glutamate synthase
IC764_01600	COG1704	LemA family
IC764_01605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC764_01615	COG4969	Belongs to the N-Me-Phe pilin family
IC764_01625	COG3307	-O-antigen
IC764_01645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC764_01660	COG0194	GDP metabolic process
IC764_01675	COG4969	Belongs to the N-Me-Phe pilin family
IC764_01700	COG4969	Belongs to the N-Me-Phe pilin family
IC764_01715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC764_01725	COG0335	large ribosomal subunit rRNA binding
IC764_01735	COG5380	lipid catabolic process
IC764_01740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC764_01760	COG5006	permease, DMT superfamily
IC764_01765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC764_01770	COG0277	FAD linked oxidase domain protein
IC764_01780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC764_01785	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC764_01800	COG1289	transmembrane transporter activity
IC764_01810	COG0628	permease
IC764_01815	COG1192	Involved in chromosome partitioning
IC764_01845	COG0833	amino acid
IC764_01850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC764_01855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC764_01865	COG1012	belongs to the aldehyde dehydrogenase family
IC764_01905	COG0583	DNA-binding transcription factor activity
IC764_01910	COG1794	racemase activity, acting on amino acids and derivatives
IC764_01915	COG0583	DNA-binding transcription factor activity
IC764_01935	COG0752	glycyl-tRNA synthetase alpha subunit
IC764_01960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC764_01960	COG0517	IMP dehydrogenase activity
IC764_01960	COG0617	tRNA 3'-terminal CCA addition
IC764_01965	COG1983	PspC domain protein
IC764_01975	COG1960	acyl-CoA dehydrogenase activity
IC764_01990	COG0408	coproporphyrinogen oxidase activity
IC764_02010	COG0513	Belongs to the DEAD box helicase family
IC764_02015	COG1127	ABC transporter
IC764_02020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC764_02030	COG2854	intermembrane phospholipid transfer
IC764_02040	COG0598	Magnesium transport protein CorA
IC764_02050	COG0494	nUDIX hydrolase
IC764_02055	COG1040	competence protein
IC764_02060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC764_02075	COG2937	Belongs to the GPAT DAPAT family
IC764_02080	COG1946	Acyl-CoA thioesterase
IC764_02085	COG1301	dicarboxylic acid transport
IC764_02100	COG1959	2 iron, 2 sulfur cluster binding
IC764_02105	COG1017	nitric oxide dioxygenase activity
IC764_02105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC764_02110	COG0433	COG0433 Predicted ATPase
IC764_02115	COG0626	cystathionine gamma-synthase activity
IC764_02130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC764_02135	COG0088	Forms part of the polypeptide exit tunnel
IC764_02270	COG1960	acyl-CoA dehydrogenase activity
IC764_02275	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC764_02305	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC764_02310	COG0339	signal peptide processing
IC764_02315	COG0557	exoribonuclease II activity
IC764_02360	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC764_02365	COG2169	Transcriptional regulator
IC764_02375	COG1295	ribonuclease BN
IC764_02410	COG1702	phosphate starvation-inducible protein PhoH
IC764_02420	COG1196	nuclear chromosome segregation
IC764_02420	COG0739	heme binding
IC764_02420	COG0741	lytic transglycosylase activity
IC764_02450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC764_02455	COG1183	phosphatidylcholine synthase activity
IC764_02520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC764_02525	COG1309	transcriptional regulator
IC764_02540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC764_02545	COG1960	acyl-CoA dehydrogenase activity
IC764_02550	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC764_02550	COG1024	Enoyl-CoA hydratase
IC764_02585	COG2969	positive regulation of protein catabolic process
IC764_02595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC764_02600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC764_02605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC764_02610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC764_02615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC764_02635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC764_02645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC764_02650	COG1408	metallophosphoesterase
IC764_02660	COG2199	diguanylate cyclase activity
IC764_02695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC764_02720	COG1607	acyl-coa hydrolase
IC764_02755	COG2350	Protein conserved in bacteria
IC764_02765	COG0613	PHP domain protein
IC764_02770	COG3781	membrane
IC764_02780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC764_02785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC764_02795	COG1862	Preprotein translocase
IC764_02830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC764_02840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC764_02855	COG2194	sulfuric ester hydrolase activity
IC764_02865	COG0726	polysaccharide deacetylase
IC764_02870	COG0463	Glycosyl transferase, family 2
IC764_02875	COG0438	transferase activity, transferring glycosyl groups
IC764_02915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC764_02950	COG1960	acyl-CoA dehydrogenase activity
IC764_02955	COG1960	acyl-CoA dehydrogenase activity
IC764_02965	COG2205	protein histidine kinase activity
IC764_02970	COG0745	RESPONSE REGULATOR receiver
IC764_02980	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC764_03000	COG2096	Adenosyltransferase
IC764_03005	COG4206	TonB-dependent receptor
IC764_03055	COG0285	dihydrofolate synthase activity
IC764_03075	COG0450	alkyl hydroperoxide reductase
IC764_03090	COG0477	Major facilitator Superfamily
IC764_03095	COG1272	protein, Hemolysin III
IC764_03105	COG2153	protein acetylation
IC764_03125	COG0183	Belongs to the thiolase family
IC764_03130	COG2207	Transcriptional regulator
IC764_03150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC764_03165	COG0183	Belongs to the thiolase family
IC764_03175	COG2885	chlorophyll binding
IC764_03175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC764_03185	COG1690	Belongs to the RtcB family
IC764_03190	COG0833	amino acid
IC764_03200	COG2233	PERMEase
IC764_03205	COG1217	gtp-binding protein TYPA
IC764_03230	COG2094	Belongs to the DNA glycosylase MPG family
IC764_03235	COG4772	TonB-dependent receptor
IC764_03240	COG1902	pentaerythritol trinitrate reductase activity
IC764_03245	COG0679	Auxin Efflux Carrier
IC764_03255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC764_03260	COG0354	folic acid binding
IC764_03275	COG2233	PERMEase
IC764_03280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC764_03285	COG0251	oxidation-reduction process
IC764_03290	COG1335	isochorismatase
IC764_03295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_03305	COG0596	Alpha beta hydrolase
IC764_03310	COG3189	MarR family transcriptional regulator
IC764_03315	COG2824	Alkylphosphonate utilization operon protein PhnA
IC764_03320	COG3422	double-strand break repair
IC764_03360	COG0840	transmembrane signaling receptor activity
IC764_03375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC764_03400	COG2832	Protein of unknown function (DUF454)
IC764_03405	COG1376	ErfK ybiS ycfS ynhG family protein
IC764_03455	COG1289	transmembrane transporter activity
IC764_03460	COG2814	Major facilitator Superfamily
IC764_03480	COG1115	amino acid carrier protein
IC764_03485	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC764_03490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC764_03495	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC764_03525	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC764_03535	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC764_03540	COG1077	Cell shape determining protein MreB Mrl
IC764_03545	COG1792	Involved in formation and maintenance of cell shape
IC764_03550	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC764_03555	COG0424	maF-like protein
IC764_03560	COG1530	ribonuclease E activity
IC764_03570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC764_03590	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC764_03615	COG2207	Transcriptional regulator
IC764_03645	COG3046	protein related to deoxyribodipyrimidine photolyase
IC764_03650	COG2816	NAD+ diphosphatase activity
IC764_03655	COG1113	amino acid transport
IC764_03660	COG2828	Protein conserved in bacteria
IC764_03665	COG0142	geranyltranstransferase activity
IC764_03670	COG2315	Protein conserved in bacteria
IC764_03685	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC764_03705	COG2194	sulfuric ester hydrolase activity
IC764_03710	COG0745	RESPONSE REGULATOR receiver
IC764_03715	COG0642	Histidine kinase
IC764_03725	COG0004	ammonium transporteR
IC764_03730	COG0583	DNA-binding transcription factor activity
IC764_03750	COG0525	valine-tRNA ligase activity
IC764_03760	COG0525	valine-tRNA ligase activity
IC764_03770	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_03780	COG0393	Putative heavy-metal-binding
IC764_03785	COG0393	Putative heavy-metal-binding
IC764_03790	COG1538	Outer membrane efflux protein
IC764_03800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_03805	COG0671	phosphoesterase, PA-phosphatase related
IC764_03835	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC764_03850	COG1648	precorrin-2 dehydrogenase activity
IC764_03850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC764_03855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC764_03860	COG1733	regulation of RNA biosynthetic process
IC764_03870	COG0531	amino acid
IC764_03885	COG0321	lipoyl(octanoyl) transferase activity
IC764_03890	COG2921	Belongs to the UPF0250 family
IC764_03925	COG2009	succinate dehydrogenase
IC764_03930	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC764_03935	COG1053	succinate dehydrogenase
IC764_03940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC764_03965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC764_03985	COG2354	Protein conserved in bacteria
IC764_03990	COG2321	neutral zinc metallopeptidase
IC764_04010	COG0589	response to stress
IC764_04030	COG0505	Belongs to the CarA family
IC764_04055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC764_04060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC764_04110	COG0477	Major facilitator Superfamily
IC764_04115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC764_04130	COG1597	lipid kinase activity
IC764_04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC764_04160	COG0584	glycerophosphoryl diester phosphodiesterase
IC764_04180	COG0741	lytic transglycosylase activity
IC764_04200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC764_04205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC764_04265	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC764_04265	COG0644	oxidoreductase
IC764_04270	COG1960	acyl-CoA dehydrogenase activity
IC764_04275	COG1024	Enoyl-CoA hydratase
IC764_04280	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC764_04285	COG0183	Belongs to the thiolase family
IC764_04290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC764_04310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_04315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_04330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC764_04350	COG3811	Belongs to the UPF0386 family
IC764_04415	COG1309	transcriptional regulator
IC764_04420	COG1902	pentaerythritol trinitrate reductase activity
IC764_04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC764_04425	COG0596	Alpha beta hydrolase
IC764_04430	COG0596	Alpha beta hydrolase
IC764_04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC764_04435	COG0596	Alpha beta hydrolase
IC764_04440	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_04445	COG0583	DNA-binding transcription factor activity
IC764_04450	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC764_04455	COG1012	belongs to the aldehyde dehydrogenase family
IC764_04475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_04480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_04485	COG0778	Nitroreductase
IC764_04500	COG1929	Belongs to the glycerate kinase type-1 family
IC764_04505	COG0243	molybdopterin cofactor binding
IC764_04510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC764_04515	COG3339	Conserved Protein
IC764_04540	COG1115	amino acid carrier protein
IC764_04545	COG1113	amino acid transport
IC764_04555	COG0019	diaminopimelate decarboxylase activity
IC764_04570	COG1280	lysine exporter protein (LysE YggA)
IC764_04575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC764_04595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC764_04605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC764_04615	COG0463	Glycosyl transferase, family 2
IC764_04635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_04670	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC764_04675	COG1136	(ABC) transporter
IC764_04680	COG2333	competence protein COMEC
IC764_04680	COG0658	competence protein
IC764_04690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC764_04690	COG0616	signal peptide processing
IC764_04695	COG0596	Alpha beta hydrolase
IC764_04700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC764_04710	COG0628	permease
IC764_04745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC764_04765	COG0823	Involved in the tonB-independent uptake of proteins
IC764_04785	COG0824	Thioesterase
IC764_04790	COG1473	amidohydrolase
IC764_04815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC764_04815	COG0047	phosphoribosylformylglycinamidine synthase activity
IC764_04820	COG2814	Major facilitator Superfamily
IC764_04835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC764_04840	COG1024	Enoyl-CoA hydratase
IC764_04845	COG1051	belongs to the nudix hydrolase family
IC764_04845	COG1056	cytidyltransferase-related domain
IC764_04860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC764_04875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC764_04880	COG0602	queuosine metabolic process
IC764_04890	COG4625	pathogenesis
IC764_04895	COG0583	DNA-binding transcription factor activity
IC764_04900	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC764_04905	COG4208	sulfate ABC transporter
IC764_04910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC764_04920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC764_04925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC764_04930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC764_04950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC764_04960	COG0481	GTPase activity
IC764_04965	COG0681	Belongs to the peptidase S26 family
IC764_04980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC764_04990	COG1381	Involved in DNA repair and RecF pathway recombination
IC764_04995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC764_05005	COG4221	oxidoreductase activity
IC764_05030	COG0436	Aminotransferase
IC764_05050	COG3706	GGDEF domain
IC764_05055	COG0556	nucleotide-excision repair
IC764_05110	COG2070	2-Nitropropane dioxygenase
IC764_05125	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC764_05140	COG1215	transferase activity, transferring glycosyl groups
IC764_05155	COG0415	Belongs to the DNA photolyase family
IC764_05165	COG1252	NADH dehydrogenase
IC764_05170	COG1686	Belongs to the peptidase S11 family
IC764_05185	COG1187	pseudouridine synthase activity
IC764_05375	COG3728	DNA packaging
IC764_05375	COG5484	DNA packaging
IC764_05485	COG0741	lytic transglycosylase activity
IC764_05485	COG0739	heme binding
IC764_05485	COG1196	nuclear chromosome segregation
IC764_05555	COG0477	Major facilitator Superfamily
IC764_05560	COG0583	DNA-binding transcription factor activity
IC764_05565	COG1823	symporter activity
IC764_05575	COG0612	Peptidase, M16
IC764_05600	COG0352	thiamine-phosphate diphosphorylase activity
IC764_05635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC764_05660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC764_05665	COG0076	glutamate decarboxylase activity
IC764_05675	COG1522	sequence-specific DNA binding
IC764_05680	COG3961	Belongs to the TPP enzyme family
IC764_05685	COG1113	amino acid transport
IC764_05690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC764_05695	COG0573	inorganic phosphate transmembrane transporter activity
IC764_05705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC764_05710	COG0616	signal peptide processing
IC764_05725	COG3647	Membrane
IC764_05750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC764_05755	COG1686	Belongs to the peptidase S11 family
IC764_05780	COG0583	DNA-binding transcription factor activity
IC764_05785	COG1067	ATP-dependent peptidase activity
IC764_05810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC764_05825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC764_05830	COG1966	Carbon starvation protein
IC764_05835	COG2879	small protein
IC764_05865	COG2814	Major facilitator Superfamily
IC764_05905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC764_05910	COG2423	ornithine cyclodeaminase activity
IC764_05920	COG2964	Protein conserved in bacteria
IC764_05925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC764_05925	COG2755	lipolytic protein G-D-S-L family
IC764_05930	COG2826	transposase and inactivated derivatives, IS30 family
IC764_05935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC764_05945	COG1741	Belongs to the pirin family
IC764_05960	COG3739	integral membrane protein
IC764_05980	COG0302	gtp cyclohydrolase
IC764_05990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC764_06000	COG2840	Smr protein MutS2
IC764_06015	COG0512	Glutamine amidotransferase of anthranilate synthase
IC764_06030	COG0174	glutamine synthetase
IC764_06040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC764_06075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC764_06080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC764_06085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC764_06110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC764_06115	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC764_06130	COG1960	acyl-CoA dehydrogenase activity
IC764_06135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC764_06140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC764_06150	COG2223	nitrite transmembrane transporter activity
IC764_06160	COG0024	Methionine aminopeptidase
IC764_06165	COG0052	Belongs to the universal ribosomal protein uS2 family
IC764_06180	COG2207	Transcriptional regulator
IC764_06205	COG2951	lytic endotransglycosylase activity
IC764_06210	COG0772	Belongs to the SEDS family
IC764_06225	COG0842	Transport permease protein
IC764_06230	COG1131	(ABC) transporter
IC764_06235	COG0582	viral genome integration into host DNA
IC764_06510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IC764_06565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_06580	COG4215	(ABC) transporter
IC764_06585	COG4160	amino acid transport
IC764_06590	COG4598	ABC transporter
IC764_06600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC764_06605	COG0826	peptidase U32
IC764_06610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC764_06615	COG0384	phenazine biosynthesis protein PhzF
IC764_06625	COG1720	tRNA m6t6A37 methyltransferase activity
IC764_06635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC764_06650	COG0642	Histidine kinase
IC764_06670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC764_06675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC764_06680	COG3139	Protein of unknown function (DUF1315)
IC764_06690	COG1301	dicarboxylic acid transport
IC764_06695	COG1960	acyl-CoA dehydrogenase activity
IC764_06715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC764_06725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC764_06730	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC764_06750	COG1690	Belongs to the RtcB family
IC764_06755	COG1234	tRNA 3'-trailer cleavage
IC764_06760	COG4650	regulator
IC764_06785	COG2363	Small membrane protein
IC764_06805	COG0513	Belongs to the DEAD box helicase family
IC764_06815	COG0778	Nitroreductase
IC764_06875	COG1610	YqeY-like protein
IC764_06905	COG2815	serine threonine protein kinase
IC764_06905	COG0515	serine threonine protein kinase
IC764_07010	COG1335	isochorismatase
IC764_07015	COG0583	DNA-binding transcription factor activity
IC764_07035	COG0596	Alpha beta hydrolase
IC764_07045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC764_07055	COG0786	glutamate:sodium symporter activity
IC764_07060	COG0475	glutathione-regulated potassium exporter activity
IC764_07060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC764_07065	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_07140	COG1309	transcriptional regulator
IC764_07150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC764_07150	COG2169	Transcriptional regulator
IC764_07165	COG2985	domain, Protein
IC764_07190	COG2995	paraquat-inducible protein a
IC764_07195	COG3008	intermembrane lipid transfer
IC764_07195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC764_07205	COG2351	hydroxyisourate hydrolase activity
IC764_07220	COG5002	protein histidine kinase activity
IC764_07245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC764_07255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC764_07260	COG0642	Histidine kinase
IC764_07265	COG0745	RESPONSE REGULATOR receiver
IC764_07290	COG2175	clavaminate synthase activity
IC764_07295	COG3246	L-lysine catabolic process to acetate
IC764_07300	COG2814	Major facilitator Superfamily
IC764_07315	COG2855	membrane
IC764_07360	COG1301	dicarboxylic acid transport
IC764_07375	COG2011	ABC-type metal ion transport system permease component
IC764_07380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC764_07385	COG1464	Belongs to the NlpA lipoprotein family
IC764_07390	COG0151	Belongs to the GarS family
IC764_07395	COG0138	bifunctional purine biosynthesis protein purh
IC764_07400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC764_07430	COG2308	Evidence 4 Homologs of previously reported genes of
IC764_07440	COG1305	Transglutaminase-like
IC764_07450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC764_07455	COG0305	Participates in initiation and elongation during chromosome replication
IC764_07480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC764_07490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC764_07520	COG1649	PFAM Uncharacterised BCR, COG1649
IC764_07520	COG0726	polysaccharide deacetylase
IC764_07525	COG1215	transferase activity, transferring glycosyl groups
IC764_07530	COG3658	cytochrome
IC764_07540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_07560	COG2890	protein-(glutamine-N5) methyltransferase activity
IC764_07565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC764_07570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC764_07585	COG1960	acyl-CoA dehydrogenase activity
IC764_07590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC764_07595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC764_07620	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC764_07625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC764_07630	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC764_07635	COG2205	protein histidine kinase activity
IC764_07640	COG0745	RESPONSE REGULATOR receiver
IC764_07645	COG0174	glutamine synthetase
IC764_07665	COG0729	surface antigen
IC764_07695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC764_07700	COG2814	Major facilitator Superfamily
IC764_07710	COG0583	DNA-binding transcription factor activity
IC764_07725	COG1187	pseudouridine synthase activity
IC764_07745	COG0802	atpase or kinase
IC764_07750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC764_07760	COG1923	regulation of RNA biosynthetic process
IC764_07765	COG0697	spore germination
IC764_07790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC764_07795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC764_07795	COG0519	Catalyzes the synthesis of GMP from XMP
IC764_07800	COG4302	ethanolamine ammonia-lyase activity
IC764_07805	COG4303	Ethanolamine ammonia lyase large subunit
IC764_07810	COG0531	amino acid
IC764_07830	COG1454	alcohol dehydrogenase
IC764_07835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC764_07845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC764_07865	COG0308	aminopeptidase N
IC764_07895	COG0625	glutathione transferase activity
IC764_07955	COG4264	IucA IucC family
IC764_07965	COG4264	IucA IucC family
IC764_07970	COG2423	ornithine cyclodeaminase activity
IC764_07975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC764_07985	COG0668	transmembrane transport
IC764_08030	COG0488	(ABC) transporter
IC764_08035	COG0589	response to stress
IC764_08060	COG3135	benzoate transporter
IC764_08065	COG1522	sequence-specific DNA binding
IC764_08075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC764_08080	COG0583	DNA-binding transcription factor activity
IC764_08090	COG0183	Belongs to the thiolase family
IC764_08095	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_08100	COG2030	dehydratase
IC764_08105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC764_08130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC764_08145	COG0824	Thioesterase
IC764_08150	COG1454	alcohol dehydrogenase
IC764_08160	COG1335	isochorismatase
IC764_08175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC764_08205	COG0069	glutamate synthase activity
IC764_08265	COG0511	ligase activity, forming carbon-carbon bonds
IC764_08285	COG1116	anion transmembrane transporter activity
IC764_08285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC764_08290	COG0745	RESPONSE REGULATOR receiver
IC764_08300	COG2146	nitrite reductase [NAD(P)H] activity
IC764_08300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC764_08305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC764_08310	COG0243	molybdopterin cofactor binding
IC764_08320	COG0243	molybdopterin cofactor binding
IC764_08325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC764_08340	COG0315	cyclic pyranopterin monophosphate synthase activity
IC764_08340	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC764_08345	COG0303	'Molybdopterin
IC764_08355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC764_08360	COG0697	spore germination
IC764_08380	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC764_08385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC764_08440	COG2204	response regulator
IC764_08445	COG3852	Histidine kinase
IC764_08470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC764_08475	COG0575	Belongs to the CDS family
IC764_08490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC764_08510	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC764_08525	COG2137	regulation of response to DNA damage stimulus
IC764_08535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC764_08540	COG1011	Hydrolase
IC764_08555	COG1522	sequence-specific DNA binding
IC764_08565	COG1113	amino acid transport
IC764_08580	COG0659	secondary active sulfate transmembrane transporter activity
IC764_08595	COG5001	Diguanylate cyclase
IC764_08595	COG3300	MHYT domain
IC764_08615	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC764_08615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC764_08615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC764_08620	COG1105	Belongs to the carbohydrate kinase PfkB family
IC764_08625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC764_08625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC764_08655	COG0024	Methionine aminopeptidase
IC764_08660	COG0583	DNA-binding transcription factor activity
IC764_08670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC764_08675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC764_08680	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC764_08705	COG0552	protein localization to endoplasmic reticulum
IC764_08730	COG4890	Cyd operon protein YbgT
IC764_08735	COG1294	oxidase, subunit
IC764_08750	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC764_08760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC764_08765	COG4774	siderophore transport
IC764_08780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC764_08785	COG0569	domain protein
IC764_08790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC764_08820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC764_08825	COG0542	response to heat
IC764_08850	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC764_08850	COG1902	pentaerythritol trinitrate reductase activity
IC764_08890	COG0148	phosphopyruvate hydratase activity
IC764_08895	COG2323	membrane
IC764_08905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC764_08915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC764_08920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC764_08925	COG0183	Belongs to the thiolase family
IC764_08930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC764_08935	COG0596	Alpha beta hydrolase
IC764_08940	COG2271	Major facilitator Superfamily
IC764_08945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC764_08950	COG3485	protocatechuate 3,4-dioxygenase
IC764_08955	COG3485	protocatechuate 3,4-dioxygenase
IC764_08960	COG0710	3-dehydroquinate dehydratase activity
IC764_08965	COG3420	alginic acid biosynthetic process
IC764_08970	COG3659	wide pore channel activity
IC764_08975	COG4993	Dehydrogenase
IC764_08985	COG2391	methyltransferase activity
IC764_09000	COG1414	Transcriptional regulator
IC764_09005	COG0583	DNA-binding transcription factor activity
IC764_09010	COG1960	acyl-CoA dehydrogenase activity
IC764_09035	COG2814	Major facilitator Superfamily
IC764_09045	COG0154	amidase activity
IC764_09065	COG4638	Rieske (2fe-2S)
IC764_09075	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_09085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC764_09095	COG3733	amine oxidase
IC764_09110	COG1012	belongs to the aldehyde dehydrogenase family
IC764_09115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC764_09120	COG0183	Belongs to the thiolase family
IC764_09125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC764_09130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC764_09140	COG4829	muconolactone delta-isomerase
IC764_09145	COG4948	Mandelate Racemase Muconate Lactonizing
IC764_09150	COG0583	DNA-binding transcription factor activity
IC764_09180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC764_09205	COG1309	transcriptional regulator
IC764_09290	COG2188	Transcriptional regulator
IC764_09305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC764_09320	COG2271	Major facilitator Superfamily
IC764_09330	COG1566	PFAM secretion protein HlyD family protein
IC764_09360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC764_09365	COG1120	ATPase activity
IC764_09385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC764_09505	COG2175	clavaminate synthase activity
IC764_09510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC764_09525	COG0667	Aldo Keto reductase
IC764_09530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_09545	COG2175	clavaminate synthase activity
IC764_09575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC764_09580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_09585	COG4771	TonB-dependent receptor
IC764_09615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_09620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC764_09625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC764_09630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC764_09645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC764_09650	COG0805	protein transport
IC764_09660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_09680	COG1132	(ABC) transporter
IC764_09685	COG1132	(ABC) transporter
IC764_09705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC764_09710	COG0601	transmembrane transport
IC764_09740	COG3539	Fimbrial protein
IC764_09765	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC764_09775	COG0753	catalase activity
IC764_09785	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC764_09790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC764_09800	COG2205	protein histidine kinase activity
IC764_09805	COG0745	RESPONSE REGULATOR receiver
IC764_09810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_09815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_09875	COG4771	TonB-dependent receptor
IC764_09880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_09885	COG1535	isochorismatase
IC764_09885	COG3433	isochorismatase activity
IC764_09890	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC764_09895	COG1169	isochorismate synthase
IC764_09900	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_09910	COG3251	PFAM MbtH domain protein
IC764_09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC764_09940	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC764_09945	COG4149	molybdate abc transporter
IC764_09950	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC764_09960	COG4638	Rieske (2fe-2S)
IC764_09965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC764_09970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC764_09970	COG0543	2 iron, 2 sulfur cluster binding
IC764_09985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC764_09995	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_10015	COG2207	Transcriptional regulator
IC764_10020	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_10025	COG2610	gluconate transmembrane transporter activity
IC764_10030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC764_10060	COG2814	Major facilitator Superfamily
IC764_10085	COG0583	DNA-binding transcription factor activity
IC764_10100	COG2031	fatty acid transporter
IC764_10105	COG0183	Belongs to the thiolase family
IC764_10110	COG0583	DNA-binding transcription factor activity
IC764_10115	COG0583	DNA-binding transcription factor activity
IC764_10130	COG1027	Aspartate ammonia-lyase
IC764_10140	COG0477	Major facilitator Superfamily
IC764_10150	COG3708	Transcriptional regulator
IC764_10150	COG2207	Transcriptional regulator
IC764_10165	COG0730	response to heat
IC764_10175	COG3453	Protein conserved in bacteria
IC764_10175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC764_10185	COG3781	membrane
IC764_10190	COG1063	alcohol dehydrogenase
IC764_10200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC764_10205	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC764_10210	COG0022	dehydrogenase e1 component
IC764_10215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC764_10220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC764_10235	COG3706	GGDEF domain
IC764_10250	COG0133	tryptophan synthase activity
IC764_10260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC764_10295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC764_10320	COG2226	methyltransferase
IC764_10370	COG0842	Transport permease protein
IC764_10375	COG0842	Transport permease protein
IC764_10380	COG1131	(ABC) transporter
IC764_10395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC764_10400	COG4773	Receptor
IC764_10420	COG0730	response to heat
IC764_10425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC764_10440	COG0406	alpha-ribazole phosphatase activity
IC764_10445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC764_10460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC764_10465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC764_10480	COG1960	acyl-CoA dehydrogenase activity
IC764_10485	COG1960	acyl-CoA dehydrogenase activity
IC764_10490	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_10495	COG2207	Transcriptional regulator
IC764_10500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC764_10505	COG0776	regulation of translation
IC764_10530	COG0822	iron-sulfur transferase activity
IC764_10535	COG0316	Belongs to the HesB IscA family
IC764_10565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC764_10585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC764_10590	COG0702	epimerase
IC764_10620	COG4172	Belongs to the ABC transporter superfamily
IC764_10625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC764_10630	COG0601	transmembrane transport
IC764_10655	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC764_10680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC764_10800	COG4695	Portal protein
IC764_10880	COG0305	Participates in initiation and elongation during chromosome replication
IC764_10895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC764_10940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC764_10955	COG2431	L-lysine efflux transmembrane transporter activity
IC764_10970	COG0776	regulation of translation
IC764_11035	COG0084	hydrolase, TatD family'
IC764_11055	COG1663	tetraacyldisaccharide 4'-kinase activity
IC764_11060	COG1132	(ABC) transporter
IC764_11070	COG0811	peptide transport
IC764_11075	COG1475	DNA binding
IC764_11080	COG1192	Involved in chromosome partitioning
IC764_11090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC764_11130	COG0424	maF-like protein
IC764_11135	COG2850	peptidyl-arginine hydroxylation
IC764_11155	COG3619	membrane
IC764_11160	COG3122	Protein conserved in bacteria
IC764_11165	COG1132	(ABC) transporter
IC764_11185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC764_11190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC764_11200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC764_11200	COG0506	proline dehydrogenase activity
IC764_11200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC764_11205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC764_11220	COG3698	Phosphodiester glycosidase
IC764_11230	COG2353	YceI-like domain
IC764_11245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC764_11285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC764_11285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC764_11310	COG3539	Fimbrial protein
IC764_11315	COG3121	Chaperone
IC764_11335	COG0697	spore germination
IC764_11345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC764_11355	COG0583	DNA-binding transcription factor activity
IC764_11360	COG2826	transposase and inactivated derivatives, IS30 family
IC764_11380	COG2197	response regulator
IC764_11405	COG1522	sequence-specific DNA binding
IC764_11415	COG1126	abc transporter atp-binding protein
IC764_11420	COG0765	amino acid transport
IC764_11425	COG0765	amino acid transport
IC764_11455	COG1464	Belongs to the NlpA lipoprotein family
IC764_11465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC764_11470	COG2011	ABC-type metal ion transport system permease component
IC764_11475	COG0012	GTP binding
IC764_11500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC764_11535	COG1917	Cupin 2, conserved barrel domain protein
IC764_11535	COG2207	Transcriptional regulator
IC764_11540	COG0386	Belongs to the glutathione peroxidase family
IC764_11550	COG0436	Aminotransferase
IC764_11555	COG1301	dicarboxylic acid transport
IC764_11590	COG3634	alkyl hydroperoxide reductase activity
IC764_11605	COG0583	DNA-binding transcription factor activity
IC764_11610	COG0431	NADPH-dependent FMN reductase
IC764_11615	COG0798	PFAM Bile acid sodium symporter
IC764_11620	COG0640	Transcriptional regulator
IC764_11635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC764_11655	COG1953	Uracil, thiamine, allantoin
IC764_11665	COG2175	clavaminate synthase activity
IC764_11670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC764_11675	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC764_11680	COG4521	taurine ABC transporter
IC764_11690	COG0477	Major facilitator Superfamily
IC764_11710	COG1271	oxidase subunit
IC764_11715	COG1294	oxidase, subunit
IC764_11725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC764_11745	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC764_11765	COG3052	prosthetic group binding
IC764_11770	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC764_11795	COG1346	cytolysis
IC764_11805	COG0583	DNA-binding transcription factor activity
IC764_11810	COG0625	glutathione transferase activity
IC764_11815	COG0625	glutathione transferase activity
IC764_11820	COG0583	DNA-binding transcription factor activity
IC764_11835	COG1045	serine acetyltransferase
IC764_11840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC764_11845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC764_11850	COG1280	lysine exporter protein (LysE YggA)
IC764_11860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC764_11865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC764_11875	COG0765	amino acid transport
IC764_11880	COG0765	amino acid transport
IC764_11920	COG0784	Response regulator, receiver
IC764_11920	COG2205	protein histidine kinase activity
IC764_11940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC764_11960	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_12005	COG0583	DNA-binding transcription factor activity
IC764_12025	COG0318	PFAM AMP-dependent synthetase and ligase
IC764_12030	COG1309	transcriptional regulator
IC764_12035	COG1960	acyl-CoA dehydrogenase activity
IC764_12040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC764_12045	COG1024	Enoyl-CoA hydratase
IC764_12050	COG4770	biotin carboxylase activity
IC764_12060	COG0583	DNA-binding transcription factor activity
IC764_12075	COG1960	acyl-CoA dehydrogenase activity
IC764_12085	COG2814	Major facilitator Superfamily
IC764_12095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC764_12100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC764_12105	COG2814	Major facilitator Superfamily
IC764_12110	COG1960	acyl-CoA dehydrogenase activity
IC764_12115	COG1024	Enoyl-CoA hydratase
IC764_12120	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_12125	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC764_12130	COG0183	Belongs to the thiolase family
IC764_12140	COG2814	Major facilitator Superfamily
IC764_12155	COG1024	Enoyl-CoA hydratase
IC764_12165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC764_12170	COG1960	acyl-CoA dehydrogenase activity
IC764_12175	COG2814	Major facilitator Superfamily
IC764_12180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC764_12185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC764_12200	COG3842	ATPase activity
IC764_12205	COG1840	ABC-type Fe3 transport system, periplasmic component
IC764_12220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC764_12225	COG1414	Transcriptional regulator
IC764_12235	COG0583	DNA-binding transcription factor activity
IC764_12250	COG3038	cytochrome b561
IC764_12255	COG0753	catalase activity
IC764_12260	COG0531	amino acid
IC764_12265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC764_12280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC764_12285	COG1309	transcriptional regulator
IC764_12325	COG3179	chitinase
IC764_12345	COG0406	alpha-ribazole phosphatase activity
IC764_12355	COG2050	protein possibly involved in aromatic compounds catabolism
IC764_12365	COG3327	negative regulation of DNA-templated transcription, initiation
IC764_12370	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC764_12380	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC764_12385	COG1024	Enoyl-CoA hydratase
IC764_12390	COG1024	Enoyl-CoA hydratase
IC764_12395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC764_12400	COG2151	metal-sulfur cluster biosynthetic enzyme
IC764_12405	COG3396	Phenylacetate-CoA oxygenase
IC764_12410	COG3460	Phenylacetate-CoA oxygenase
IC764_12415	COG3396	Phenylacetate-CoA oxygenase
IC764_12420	COG2030	dehydratase
IC764_12420	COG1012	belongs to the aldehyde dehydrogenase family
IC764_12425	COG1760	l-serine dehydratase
IC764_12435	COG0789	Transcriptional regulator
IC764_12445	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC764_12450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC764_12465	COG2807	transmembrane transport
IC764_12470	COG0590	tRNA wobble adenosine to inosine editing
IC764_12575	COG0477	Major facilitator Superfamily
IC764_12590	COG1116	anion transmembrane transporter activity
IC764_12595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC764_12605	COG0864	Transcriptional regulator
IC764_12620	COG1733	regulation of RNA biosynthetic process
IC764_12625	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC764_12630	COG0439	Biotin carboxylase
IC764_12645	COG1063	alcohol dehydrogenase
IC764_12690	COG0038	chloride channel
IC764_12695	COG4770	biotin carboxylase activity
IC764_12715	COG1914	H( )-stimulated, divalent metal cation uptake system
IC764_12720	COG0583	DNA-binding transcription factor activity
IC764_12730	COG1595	DNA-templated transcription, initiation
IC764_12740	COG3220	belongs to the UPF0276 family
IC764_12755	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_12770	COG2076	Multidrug Resistance protein
IC764_12785	COG3713	MltA-interacting MipA family protein
IC764_12790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC764_12835	COG3209	COG3209 Rhs family protein
IC764_12920	COG1309	transcriptional regulator
IC764_12925	COG1278	Cold shock
IC764_12940	COG1522	sequence-specific DNA binding
IC764_12950	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_12960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC764_12965	COG4774	siderophore transport
IC764_12985	COG2814	Major facilitator Superfamily
IC764_13000	COG0402	S-adenosylhomocysteine deaminase activity
IC764_13005	COG0583	DNA-binding transcription factor activity
IC764_13015	COG1271	oxidase subunit
IC764_13020	COG1294	oxidase, subunit
IC764_13030	COG1469	GTP cyclohydrolase I activity
IC764_13095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC764_13105	COG4122	O-methyltransferase activity
IC764_13135	COG1538	Outer membrane efflux protein
IC764_13140	COG1137	ATPase activity
IC764_13145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC764_13155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC764_13160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC764_13160	COG0517	IMP dehydrogenase activity
IC764_13180	COG0667	Aldo Keto reductase
IC764_13190	COG2814	Major facilitator Superfamily
IC764_13220	COG1278	Cold shock
IC764_13225	COG1280	lysine exporter protein (LysE YggA)
IC764_13260	COG1570	exodeoxyribonuclease VII activity
IC764_13345	COG2871	sodium ion transport
IC764_13355	COG0583	DNA-binding transcription factor activity
IC764_13365	COG4638	Rieske (2fe-2S)
IC764_13370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC764_13375	COG0543	2 iron, 2 sulfur cluster binding
IC764_13375	COG0633	Ferredoxin
IC764_13380	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_13385	COG3135	benzoate transporter
IC764_13390	COG2814	Major facilitator Superfamily
IC764_13405	COG1643	Atp-dependent helicase
IC764_13420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_13440	COG3634	alkyl hydroperoxide reductase activity
IC764_13460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC764_13465	COG0625	glutathione transferase activity
IC764_13510	COG0542	response to heat
IC764_13525	COG1765	OsmC-like protein
IC764_13535	COG0667	Aldo Keto reductase
IC764_13550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC764_13565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC764_13575	COG0527	aspartate kinase activity
IC764_13585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC764_13595	COG3038	cytochrome b561
IC764_13600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC764_13605	COG2252	PERMEase
IC764_13615	COG2072	flavoprotein involved in K transport
IC764_13630	COG1741	Belongs to the pirin family
IC764_13635	COG1309	transcriptional regulator
IC764_13650	COG2072	flavoprotein involved in K transport
IC764_13655	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC764_13660	COG0583	DNA-binding transcription factor activity
IC764_13675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC764_13705	COG1944	ATP diphosphatase activity
IC764_13725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC764_13740	COG2814	Major facilitator Superfamily
IC764_13745	COG1024	Enoyl-CoA hydratase
IC764_13750	COG1012	belongs to the aldehyde dehydrogenase family
IC764_13760	COG1960	acyl-CoA dehydrogenase activity
IC764_13780	COG0697	spore germination
IC764_13820	COG1012	belongs to the aldehyde dehydrogenase family
IC764_13840	COG0531	amino acid
IC764_13850	COG1113	amino acid transport
IC764_13900	COG1846	Transcriptional regulator
IC764_13950	COG4269	membrane
IC764_13970	COG0583	DNA-binding transcription factor activity
IC764_13980	COG0251	oxidation-reduction process
IC764_13995	COG1902	pentaerythritol trinitrate reductase activity
IC764_13995	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC764_14005	COG4251	negative regulation of phosphorylation
IC764_14005	COG5001	Diguanylate cyclase
IC764_14005	COG2203	Gaf domain
IC764_14005	COG3706	GGDEF domain
IC764_14015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC764_14040	COG4172	Belongs to the ABC transporter superfamily
IC764_14045	COG4239	(ABC) transporter, permease
IC764_14050	COG4174	ABC transporter (Permease)
IC764_14060	COG0741	lytic transglycosylase activity
IC764_14060	COG1388	LysM domain
IC764_14105	COG0583	DNA-binding transcription factor activity
IC764_14130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC764_14135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC764_14140	COG0006	proline dipeptidase activity
IC764_14470	COG1674	ftsk spoiiie
IC764_14500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC764_14540	COG3384	dioxygenase
IC764_14550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC764_14555	COG2878	Part of a membrane complex involved in electron transport
IC764_14560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC764_14585	COG0768	penicillin binding
IC764_14590	COG0742	ribosomal rna small subunit methyltransferase
IC764_14610	COG0830	nickel cation binding
IC764_14620	COG0804	urea catabolic process
IC764_14660	COG1253	flavin adenine dinucleotide binding
IC764_14665	COG2851	Citrate transporter
IC764_14715	COG1773	rubredoxin
IC764_14720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC764_14730	COG0583	DNA-binding transcription factor activity
IC764_14755	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC764_14760	COG4181	ATPase activity
IC764_14805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC764_14825	COG0306	phosphate transporter
IC764_14860	COG2223	nitrite transmembrane transporter activity
IC764_14865	COG2207	Transcriptional regulator
IC764_14870	COG2066	Belongs to the glutaminase family
IC764_14875	COG0242	peptide deformylase activity
IC764_14890	COG0028	Belongs to the TPP enzyme family
IC764_14905	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_14910	COG2267	carboxylic ester hydrolase activity
IC764_14920	COG2271	Major facilitator Superfamily
IC764_14955	COG1414	Transcriptional regulator
IC764_14985	COG1024	Enoyl-CoA hydratase
IC764_14995	COG1215	transferase activity, transferring glycosyl groups
IC764_15000	COG1649	PFAM Uncharacterised BCR, COG1649
IC764_15000	COG0726	polysaccharide deacetylase
IC764_15010	COG4681	YaeQ
IC764_15020	COG0523	cobalamin synthesis protein
IC764_15030	COG1607	acyl-coa hydrolase
IC764_15040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC764_15045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC764_15050	COG1309	transcriptional regulator
IC764_15075	COG2040	homocysteine
IC764_15080	COG0531	amino acid
IC764_15100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC764_15105	COG0477	Major facilitator Superfamily
IC764_15140	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC764_15145	COG3586	endonuclease activity
IC764_15205	COG0405	Gamma-glutamyltransferase
IC764_15210	COG2814	Major facilitator Superfamily
IC764_15220	COG2050	protein possibly involved in aromatic compounds catabolism
IC764_15235	COG1090	epimerase
IC764_15255	COG0420	3'-5' exonuclease activity
IC764_15265	COG1968	undecaprenyl-diphosphatase activity
IC764_15285	COG0735	belongs to the Fur family
IC764_15290	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC764_15295	COG2914	Belongs to the UPF0125 (RnfH) family
IC764_15310	COG0121	glutamine amidotransferase
IC764_15325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC764_15335	COG0210	DNA helicase
IC764_15340	COG2885	chlorophyll binding
IC764_15345	COG0204	Acyl-transferase
IC764_15360	COG2894	cell division
IC764_15375	COG1280	lysine exporter protein (LysE YggA)
IC764_15380	COG1674	ftsk spoiiie
IC764_15385	COG0492	ferredoxin-NADP+ reductase activity
IC764_15390	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC764_15400	COG0456	acetyltransferase
IC764_15420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC764_15430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC764_15445	COG1981	membrane
IC764_15455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC764_15455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC764_15475	COG1012	belongs to the aldehyde dehydrogenase family
IC764_15480	COG4638	Rieske (2fe-2S)
IC764_15485	COG0657	acetylesterase activity
IC764_15495	COG0473	3-isopropylmalate dehydrogenase activity
IC764_15500	COG0583	DNA-binding transcription factor activity
IC764_15520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC764_15545	COG0564	pseudouridine synthase activity
IC764_15555	COG0358	DNA primase activity
IC764_15570	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC764_15600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC764_15630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC764_15640	COG0351	phosphomethylpyrimidine kinase
IC764_15640	COG0352	thiamine-phosphate diphosphorylase activity
IC764_15640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC764_15645	COG1652	LysM domain
IC764_15670	COG1399	metal-binding, possibly nucleic acid-binding protein
IC764_15675	COG3101	peptidyl-lysine hydroxylation
IC764_15680	COG0009	L-threonylcarbamoyladenylate synthase
IC764_15685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC764_15690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC764_15705	COG4106	trans-aconitate 2-methyltransferase activity
IC764_15720	COG0596	Alpha beta hydrolase
IC764_15720	COG2226	methyltransferase
IC764_15720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC764_15725	COG1877	trehalose-phosphatase activity
IC764_15730	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC764_15735	COG2223	nitrite transmembrane transporter activity
IC764_15755	COG1196	nuclear chromosome segregation
IC764_15765	COG0730	response to heat
IC764_15780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC764_15790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC764_15835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC764_15840	COG0489	protein tyrosine kinase activity
IC764_15850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC764_15850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC764_15885	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC764_15890	COG2081	HI0933 family
IC764_15900	COG0668	transmembrane transport
IC764_15920	COG0583	DNA-binding transcription factor activity
IC764_15945	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC764_15950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC764_15965	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC764_15980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC764_16005	COG3706	GGDEF domain
IC764_16020	COG0745	RESPONSE REGULATOR receiver
IC764_16040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC764_16070	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC764_16075	COG0583	DNA-binding transcription factor activity
IC764_16125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC764_16140	COG0583	DNA-binding transcription factor activity
IC764_16150	COG0583	DNA-binding transcription factor activity
IC764_16165	COG0583	DNA-binding transcription factor activity
IC764_16170	COG1053	succinate dehydrogenase
IC764_16185	COG1309	transcriptional regulator
IC764_16195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC764_16200	COG2814	Major facilitator Superfamily
IC764_16205	COG1960	acyl-CoA dehydrogenase activity
IC764_16210	COG0583	DNA-binding transcription factor activity
IC764_16215	COG1063	alcohol dehydrogenase
IC764_16245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IC764_16250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC764_16255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC764_16275	COG2132	Multicopper oxidase
IC764_16285	COG0561	phosphatase activity
IC764_16290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC764_16300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC764_16315	COG1214	PFAM Peptidase M22, glycoprotease
IC764_16365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC764_16375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC764_16380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC764_16385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC764_16445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC764_16455	COG1846	Transcriptional regulator
IC764_16460	COG1764	response to oxidative stress
IC764_16500	COG0037	tRNA processing
IC764_16510	COG0248	Ppx GppA phosphatase
IC764_16540	COG0072	phenylalanine-tRNA ligase activity
IC764_16570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC764_16580	COG1238	metal cluster binding
IC764_16585	COG0625	glutathione transferase activity
IC764_16600	COG0318	PFAM AMP-dependent synthetase and ligase
IC764_16605	COG3028	Belongs to the UPF0307 family
IC764_16630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC764_16635	COG0617	tRNA 3'-terminal CCA addition
IC764_16640	COG1555	photosystem II stabilization
IC764_16645	COG3956	TIGRFAM MazG family protein
IC764_16655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC764_16675	COG0784	Response regulator, receiver
IC764_16675	COG2205	protein histidine kinase activity
IC764_16675	COG5002	protein histidine kinase activity
IC764_16680	COG1024	Enoyl-CoA hydratase
IC764_16685	COG2084	Dehydrogenase
IC764_16690	COG3622	Belongs to the hyi family
IC764_16725	COG0697	spore germination
IC764_16735	COG2814	Major facilitator Superfamily
IC764_16760	COG1230	cation diffusion facilitator family transporter
IC764_16775	COG2814	Major facilitator Superfamily
IC764_16880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC764_16890	COG0583	DNA-binding transcription factor activity
IC764_16900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC764_16910	COG0084	hydrolase, TatD family'
IC764_16925	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC764_16960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC764_16965	COG0440	acetolactate synthase activity
IC764_16970	COG0028	Belongs to the TPP enzyme family
IC764_16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC764_17000	COG1136	(ABC) transporter
IC764_17000	COG0577	efflux transmembrane transporter activity
IC764_17005	COG1538	Outer membrane efflux protein
IC764_17020	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC764_17025	COG1162	GTPase activity
IC764_17035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC764_17075	COG1426	Protein conserved in bacteria
IC764_17110	COG0793	Belongs to the peptidase S41A family
IC764_17135	COG1012	belongs to the aldehyde dehydrogenase family
IC764_17140	COG3265	gluconokinase activity
IC764_17150	COG0800	Aldolase
IC764_17160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC764_17165	COG0857	belongs to the CobB CobQ family
IC764_17165	COG0280	phosphate acetyltransferase
IC764_17170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC764_17170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC764_17190	COG0740	serine-type endopeptidase activity
IC764_17200	COG4774	siderophore transport
IC764_17210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC764_17220	COG2813	Specifically methylates the guanine in position
IC764_17220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC764_17315	COG0788	formyltetrahydrofolate deformylase activity
IC764_17360	COG0724	RNA recognition motif
IC764_17365	COG0210	DNA helicase
IC764_17390	COG1733	regulation of RNA biosynthetic process
IC764_17400	COG2900	Belongs to the SlyX family
IC764_17405	COG0488	(ABC) transporter
IC764_17415	COG1280	lysine exporter protein (LysE YggA)
IC764_17420	COG1560	Kdo2-lipid A biosynthetic process
IC764_17430	COG1301	dicarboxylic acid transport
IC764_17485	COG0473	3-isopropylmalate dehydrogenase activity
IC764_17555	COG0583	DNA-binding transcription factor activity
IC764_17565	COG0625	glutathione transferase activity
IC764_17570	COG2378	regulation of single-species biofilm formation
IC764_17585	COG1530	ribonuclease E activity
IC764_17590	COG0318	PFAM AMP-dependent synthetase and ligase
IC764_17605	COG0583	DNA-binding transcription factor activity
IC764_17610	COG4221	oxidoreductase activity
IC764_17615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC764_17625	COG0534	Mate efflux family protein
IC764_17640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC764_17670	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC764_17670	COG0493	'glutamate synthase
IC764_17680	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC764_17685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC764_17700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC764_17710	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC764_17710	COG0644	oxidoreductase
IC764_17725	COG4535	Mg2 and Co2 transporter CorC
IC764_17735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC764_17760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC764_17765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC764_17765	COG0475	glutathione-regulated potassium exporter activity
IC764_17770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC764_17780	COG0484	heat shock protein binding
IC764_17785	COG0789	Transcriptional regulator
IC764_17790	COG0598	Magnesium transport protein CorA
IC764_17795	COG1185	polyribonucleotide nucleotidyltransferase activity
IC764_17805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC764_17810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC764_17815	COG1074	ATP-dependent DNA helicase activity
IC764_17820	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC764_17845	COG2226	methyltransferase
IC764_17860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC764_17875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC764_17890	COG2111	Na H antiporter
IC764_17890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC764_17895	COG1006	Multisubunit Na H antiporter MnhC subunit
IC764_17900	COG0651	ATP synthesis coupled electron transport
IC764_17905	COG1863	multisubunit Na H antiporter MnhE subunit
IC764_17910	COG2212	antiporter activity
IC764_17915	COG1320	monovalent cation:proton antiporter activity
IC764_17920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC764_17930	COG0195	Participates in both transcription termination and antitermination
IC764_17980	COG0237	dephospho-CoA kinase activity
IC764_17990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC764_18000	COG0497	DNA recombination
IC764_18010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC764_18025	COG1289	transmembrane transporter activity
IC764_18040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC764_18100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC764_18115	COG0326	Molecular chaperone. Has ATPase activity
IC764_18130	COG2056	Na+-H+ antiporter family
IC764_18135	COG0596	Alpha beta hydrolase
IC764_18230	COG0546	phosphoglycolate phosphatase activity
IC764_18235	COG1716	ATPase activity
IC764_18280	COG0181	hydroxymethylbilane synthase activity
IC764_18290	COG3275	phosphorelay sensor kinase activity
IC764_18310	COG1538	Outer membrane efflux protein
IC764_18320	COG0697	spore germination
IC764_18340	COG0494	nUDIX hydrolase
IC764_18350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC764_18355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC764_18385	COG4974	Belongs to the 'phage' integrase family
IC764_18390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC764_18400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC764_18410	COG2197	response regulator
IC764_18425	COG0793	Belongs to the peptidase S41A family
IC764_18430	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC764_18435	COG0795	lipopolysaccharide-transporting ATPase activity
IC764_18440	COG0795	lipopolysaccharide-transporting ATPase activity
IC764_18475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC764_18475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC764_18485	COG0004	ammonium transporteR
IC764_18490	COG0347	Belongs to the P(II) protein family
IC764_18500	COG0606	chelatase, subunit chli
IC764_18505	COG0431	NADPH-dependent FMN reductase
IC764_18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC764_18515	COG0235	Class ii aldolase
IC764_18520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC764_18535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC764_18550	COG0318	PFAM AMP-dependent synthetase and ligase
IC764_18560	COG0477	Major facilitator Superfamily
IC764_18565	COG2860	membrane
IC764_18575	COG1253	flavin adenine dinucleotide binding
IC764_18585	COG2814	Major facilitator Superfamily
IC764_18595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC764_18630	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC764_18645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC764_18680	COG1309	transcriptional regulator
IC764_18715	COG0758	DNA mediated transformation
IC764_18725	COG0697	spore germination
IC764_18730	COG1309	transcriptional regulator
IC764_18745	COG0386	Belongs to the glutathione peroxidase family
IC764_18755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC764_18760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC764_18810	COG1121	(ABC) transporter
IC764_18815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC764_18820	COG1280	lysine exporter protein (LysE YggA)
IC764_18830	COG2826	transposase and inactivated derivatives, IS30 family
IC764_18840	COG0281	malic enzyme
IC764_18875	COG0735	belongs to the Fur family
IC764_18885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC764_18890	COG0519	Catalyzes the synthesis of GMP from XMP
IC764_18890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC764_18895	COG4399	Belongs to the UPF0754 family
IC764_18895	COG4399	Belongs to the UPF0754 family
IC764_18900	COG2259	Doxx family
IC764_18905	COG0586	Pfam SNARE associated Golgi protein
IC764_18920	COG1192	Involved in chromosome partitioning
IC764_18930	COG0271	Belongs to the BolA IbaG family
IC764_18970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC764_18970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC764_18970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC764_18970	COG3321	synthase
IC764_18975	COG1960	acyl-CoA dehydrogenase activity
IC764_18985	COG2197	response regulator
IC764_18995	COG3916	Acyl-homoserine-lactone synthase
IC764_19000	COG0477	Major facilitator Superfamily
IC764_19005	COG1024	Enoyl-CoA hydratase
IC764_19010	COG1024	Enoyl-CoA hydratase
IC764_19015	COG1960	acyl-CoA dehydrogenase activity
IC764_19020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC764_19040	COG1113	amino acid transport
IC764_19045	COG1113	amino acid transport
IC764_19050	COG0251	oxidation-reduction process
IC764_19090	COG0564	pseudouridine synthase activity
IC764_19160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC764_19175	COG1802	Transcriptional regulator
IC764_19185	COG1448	Aminotransferase
IC764_19190	COG0277	FAD linked oxidase domain protein
IC764_19200	COG2186	Transcriptional regulator
IC764_19210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC764_19230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC764_19235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC764_19250	COG0110	maltose O-acetyltransferase activity
IC764_19255	COG1216	Glycosyl transferase, family 2
IC764_19255	COG0463	Glycosyl transferase, family 2
IC764_19290	COG1086	Polysaccharide biosynthesis protein
IC764_19300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC764_19305	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC764_19315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC764_19320	COG1596	polysaccharide export
IC764_19345	COG0728	peptidoglycan biosynthetic process
IC764_19350	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC764_19405	COG0546	phosphoglycolate phosphatase activity
IC764_19410	COG1028	Short-chain dehydrogenase reductase Sdr
IC764_19425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC764_19425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC764_19435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC764_19440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC764_19445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC764_19450	COG1116	anion transmembrane transporter activity
IC764_19455	COG1309	transcriptional regulator
IC764_19460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC764_19470	COG0196	riboflavin kinase activity
IC764_19475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC764_19485	COG1047	Peptidyl-prolyl cis-trans
IC764_19525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC764_19530	COG0657	acetylesterase activity
IC764_19580	COG2951	lytic endotransglycosylase activity
IC764_19585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC764_19600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC764_19610	COG0671	phosphoesterase, PA-phosphatase related
IC764_19615	COG0861	Integral membrane protein TerC family
IC764_19625	COG0754	glutathionylspermidine amidase activity
IC764_19635	COG0402	S-adenosylhomocysteine deaminase activity
IC764_19650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC764_19685	COG0739	heme binding
IC764_19715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC764_19730	COG1192	Involved in chromosome partitioning
IC764_19780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC764_19880	COG2826	transposase and inactivated derivatives, IS30 family
IC764_19890	COG2826	transposase and inactivated derivatives, IS30 family
IC764_19965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IC764_20070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC764_20100	COG0659	secondary active sulfate transmembrane transporter activity
IC764_20105	COG0589	response to stress
IC764_20130	COG4372	Transposase
IC764_20170	COG0501	Belongs to the peptidase M48B family
IC764_20410	COG0789	Transcriptional regulator
IC764_20450	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC764_20475	COG2132	Multicopper oxidase
IC764_20490	COG2205	protein histidine kinase activity
IC764_20495	COG3174	membrane
IC764_20500	COG2217	Heavy metal translocating P-type atpase
IC764_20590	COG0210	DNA helicase
IC764_20610	COG0210	DNA helicase
IC764_20655	COG0582	viral genome integration into host DNA
IC764_20670	COG2130	NADP-dependent
IC764_20675	COG1309	transcriptional regulator
IC764_20685	COG1902	pentaerythritol trinitrate reductase activity
IC764_20695	COG1979	alcohol dehydrogenase
IC764_20710	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC764_20740	COG0477	Major facilitator Superfamily
IC764_20745	COG0697	spore germination
IC764_20755	COG0604	alcohol dehydrogenase
IC764_20755	COG3321	synthase
IC764_20760	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC764_20765	COG0583	DNA-binding transcription factor activity
IC764_20770	COG3328	transposase activity
IC764_20785	COG0659	secondary active sulfate transmembrane transporter activity
IC764_20790	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC764_20825	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
