locus-tag	class	description
IC765_00010	COG0592	DNA-directed DNA polymerase activity
IC765_00020	COG0187	DNA topoisomerase II activity
IC765_00060	COG0596	Alpha beta hydrolase
IC765_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC765_00100	COG0625	glutathione transferase activity
IC765_00110	COG0733	neurotransmitter:sodium symporter activity
IC765_00150	COG2233	PERMEase
IC765_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_00200	COG2814	Major facilitator Superfamily
IC765_00205	COG0656	L-ascorbic acid biosynthetic process
IC765_00210	COG0583	DNA-binding transcription factor activity
IC765_00230	COG1064	alcohol dehydrogenase
IC765_00250	COG1194	a g-specific adenine glycosylase
IC765_00265	COG5487	UPF0391 membrane protein
IC765_00270	COG2983	Belongs to the UPF0260 family
IC765_00275	COG2133	pyrroloquinoline quinone binding
IC765_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC765_00285	COG2116	formate transmembrane transporter activity
IC765_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC765_00315	COG0385	Bile acid
IC765_00320	COG0534	Mate efflux family protein
IC765_00325	COG1683	Conserved Protein
IC765_00340	COG0346	lactoylglutathione lyase activity
IC765_00345	COG0625	glutathione transferase activity
IC765_00355	COG1113	amino acid transport
IC765_00365	COG0523	cobalamin synthesis protein
IC765_00375	COG2188	Transcriptional regulator
IC765_00415	COG0546	phosphoglycolate phosphatase activity
IC765_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC765_00470	COG0514	ATP-dependent DNA helicase (RecQ)
IC765_00500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC765_00510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC765_00515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC765_00615	COG0534	Mate efflux family protein
IC765_00620	COG0436	Aminotransferase
IC765_00625	COG2733	membrane
IC765_00640	COG2918	glutathione biosynthetic process
IC765_00655	COG5632	N-Acetylmuramoyl-L-alanine amidase
IC765_00655	COG1388	LysM domain
IC765_00655	COG3409	Peptidoglycan-binding domain 1 protein
IC765_00675	COG3150	esterase
IC765_00695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC765_00705	COG2233	PERMEase
IC765_00710	COG2351	hydroxyisourate hydrolase activity
IC765_00760	COG1393	Belongs to the ArsC family
IC765_00805	COG0189	ligase activity
IC765_00825	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC765_00835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC765_00870	COG2119	membrane
IC765_00880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC765_00880	COG0426	domain, Protein
IC765_00930	COG1519	Transferase
IC765_00935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC765_00950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC765_00955	COG1335	isochorismatase
IC765_00960	COG1522	sequence-specific DNA binding
IC765_00990	COG3162	membrane
IC765_00995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC765_01005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC765_01025	COG1309	transcriptional regulator
IC765_01045	COG4221	oxidoreductase activity
IC765_01080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC765_01090	COG1113	amino acid transport
IC765_01100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC765_01105	COG1012	belongs to the aldehyde dehydrogenase family
IC765_01115	COG1335	isochorismatase
IC765_01160	COG1132	(ABC) transporter
IC765_01165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_01170	COG0577	efflux transmembrane transporter activity
IC765_01170	COG1136	(ABC) transporter
IC765_01195	COG0583	DNA-binding transcription factor activity
IC765_01215	COG0667	Aldo Keto reductase
IC765_01275	COG1733	regulation of RNA biosynthetic process
IC765_01280	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC765_01300	COG3550	peptidyl-serine autophosphorylation
IC765_01305	COG1396	sequence-specific DNA binding
IC765_01310	COG3177	Filamentation induced by cAMP protein fic
IC765_01350	COG2801	Transposase and inactivated derivatives
IC765_01435	COG0582	viral genome integration into host DNA
IC765_01490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC765_01505	COG2329	Antibiotic biosynthesis monooxygenase
IC765_01535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC765_01565	COG0427	acetyl-CoA hydrolase
IC765_01590	COG0659	secondary active sulfate transmembrane transporter activity
IC765_01595	COG4221	oxidoreductase activity
IC765_01605	COG0028	Belongs to the TPP enzyme family
IC765_01610	COG0488	(ABC) transporter
IC765_01685	COG0833	amino acid
IC765_01735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC765_01750	COG2226	methyltransferase
IC765_01805	COG0493	'glutamate synthase
IC765_01815	COG1704	LemA family
IC765_01820	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC765_01835	COG3307	-O-antigen
IC765_01870	COG0194	GDP metabolic process
IC765_01925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC765_01935	COG0335	large ribosomal subunit rRNA binding
IC765_01945	COG5380	lipid catabolic process
IC765_01950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC765_01970	COG5006	permease, DMT superfamily
IC765_01975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC765_01980	COG0277	FAD linked oxidase domain protein
IC765_01990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC765_01995	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC765_02025	COG0628	permease
IC765_02030	COG1192	Involved in chromosome partitioning
IC765_02065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC765_02070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC765_02080	COG1012	belongs to the aldehyde dehydrogenase family
IC765_02120	COG0583	DNA-binding transcription factor activity
IC765_02130	COG0583	DNA-binding transcription factor activity
IC765_02150	COG0752	glycyl-tRNA synthetase alpha subunit
IC765_02175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IC765_02175	COG0617	tRNA 3'-terminal CCA addition
IC765_02175	COG0517	IMP dehydrogenase activity
IC765_02180	COG1983	PspC domain protein
IC765_02205	COG0408	coproporphyrinogen oxidase activity
IC765_02225	COG0513	Belongs to the DEAD box helicase family
IC765_02230	COG1127	ABC transporter
IC765_02235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC765_02245	COG2854	intermembrane phospholipid transfer
IC765_02265	COG0494	nUDIX hydrolase
IC765_02275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC765_02295	COG1946	Acyl-CoA thioesterase
IC765_02315	COG1959	2 iron, 2 sulfur cluster binding
IC765_02320	COG1017	nitric oxide dioxygenase activity
IC765_02320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC765_02325	COG0433	COG0433 Predicted ATPase
IC765_02345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC765_02350	COG0088	Forms part of the polypeptide exit tunnel
IC765_02485	COG1960	acyl-CoA dehydrogenase activity
IC765_02490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC765_02520	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC765_02530	COG0557	exoribonuclease II activity
IC765_02575	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC765_02580	COG2169	Transcriptional regulator
IC765_02625	COG1702	phosphate starvation-inducible protein PhoH
IC765_02635	COG0741	lytic transglycosylase activity
IC765_02635	COG0739	heme binding
IC765_02635	COG1196	nuclear chromosome segregation
IC765_02665	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC765_02670	COG1183	phosphatidylcholine synthase activity
IC765_02720	COG1960	acyl-CoA dehydrogenase activity
IC765_02725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC765_02730	COG1309	transcriptional regulator
IC765_02745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC765_02790	COG2969	positive regulation of protein catabolic process
IC765_02800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC765_02805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC765_02820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC765_02840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC765_02855	COG1408	metallophosphoesterase
IC765_02865	COG2199	diguanylate cyclase activity
IC765_02900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC765_02925	COG1607	acyl-coa hydrolase
IC765_02960	COG2350	Protein conserved in bacteria
IC765_02970	COG0613	PHP domain protein
IC765_02975	COG3781	membrane
IC765_02990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC765_03000	COG1862	Preprotein translocase
IC765_03075	COG0726	polysaccharide deacetylase
IC765_03080	COG0463	Glycosyl transferase, family 2
IC765_03085	COG0438	transferase activity, transferring glycosyl groups
IC765_03160	COG1960	acyl-CoA dehydrogenase activity
IC765_03175	COG2205	protein histidine kinase activity
IC765_03180	COG0745	RESPONSE REGULATOR receiver
IC765_03190	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC765_03210	COG2096	Adenosyltransferase
IC765_03215	COG4206	TonB-dependent receptor
IC765_03300	COG0477	Major facilitator Superfamily
IC765_03305	COG1272	protein, Hemolysin III
IC765_03315	COG2153	protein acetylation
IC765_03345	COG2207	Transcriptional regulator
IC765_03405	COG0833	amino acid
IC765_03415	COG2233	PERMEase
IC765_03420	COG1217	gtp-binding protein TYPA
IC765_03445	COG2094	Belongs to the DNA glycosylase MPG family
IC765_03455	COG1902	pentaerythritol trinitrate reductase activity
IC765_03470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC765_03500	COG0251	oxidation-reduction process
IC765_03505	COG1335	isochorismatase
IC765_03510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC765_03520	COG0596	Alpha beta hydrolase
IC765_03525	COG3189	MarR family transcriptional regulator
IC765_03530	COG2824	Alkylphosphonate utilization operon protein PhnA
IC765_03535	COG3422	double-strand break repair
IC765_03575	COG0840	transmembrane signaling receptor activity
IC765_03590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC765_03615	COG2832	Protein of unknown function (DUF454)
IC765_03620	COG1376	ErfK ybiS ycfS ynhG family protein
IC765_03665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IC765_03680	COG2814	Major facilitator Superfamily
IC765_03710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC765_03715	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC765_03755	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC765_03765	COG1792	Involved in formation and maintenance of cell shape
IC765_03770	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC765_03775	COG0424	maF-like protein
IC765_03780	COG1530	ribonuclease E activity
IC765_03790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC765_03810	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC765_03855	COG0464	growth
IC765_03895	COG0305	Participates in initiation and elongation during chromosome replication
IC765_03945	COG3046	protein related to deoxyribodipyrimidine photolyase
IC765_03950	COG2816	NAD+ diphosphatase activity
IC765_03955	COG1113	amino acid transport
IC765_03965	COG0142	geranyltranstransferase activity
IC765_03970	COG2315	Protein conserved in bacteria
IC765_03985	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC765_04010	COG2194	sulfuric ester hydrolase activity
IC765_04015	COG0745	RESPONSE REGULATOR receiver
IC765_04020	COG0642	Histidine kinase
IC765_04030	COG0004	ammonium transporteR
IC765_04065	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_04075	COG0393	Putative heavy-metal-binding
IC765_04080	COG0393	Putative heavy-metal-binding
IC765_04085	COG1538	Outer membrane efflux protein
IC765_04095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_04100	COG0671	phosphoesterase, PA-phosphatase related
IC765_04145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC765_04145	COG1648	precorrin-2 dehydrogenase activity
IC765_04150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC765_04155	COG1733	regulation of RNA biosynthetic process
IC765_04165	COG0531	amino acid
IC765_04180	COG0321	lipoyl(octanoyl) transferase activity
IC765_04185	COG2921	Belongs to the UPF0250 family
IC765_04220	COG2009	succinate dehydrogenase
IC765_04225	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC765_04230	COG1053	succinate dehydrogenase
IC765_04235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC765_04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC765_04280	COG2354	Protein conserved in bacteria
IC765_04330	COG0589	response to stress
IC765_04350	COG0505	Belongs to the CarA family
IC765_04375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC765_04430	COG0477	Major facilitator Superfamily
IC765_04450	COG1597	lipid kinase activity
IC765_04495	COG2801	Transposase and inactivated derivatives
IC765_04570	COG2814	Major facilitator Superfamily
IC765_04620	COG0584	glycerophosphoryl diester phosphodiesterase
IC765_04660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC765_04665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC765_04680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_04735	COG3811	Belongs to the UPF0386 family
IC765_04785	COG1309	transcriptional regulator
IC765_04790	COG1902	pentaerythritol trinitrate reductase activity
IC765_04795	COG0596	Alpha beta hydrolase
IC765_04795	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC765_04800	COG0596	Alpha beta hydrolase
IC765_04800	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC765_04815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_04825	COG0778	Nitroreductase
IC765_04840	COG1929	Belongs to the glycerate kinase type-1 family
IC765_04845	COG0243	molybdopterin cofactor binding
IC765_04850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC765_04880	COG1115	amino acid carrier protein
IC765_04885	COG1113	amino acid transport
IC765_04895	COG0019	diaminopimelate decarboxylase activity
IC765_04915	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC765_04945	COG0463	Glycosyl transferase, family 2
IC765_04965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_05000	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC765_05005	COG1136	(ABC) transporter
IC765_05010	COG0658	competence protein
IC765_05010	COG2333	competence protein COMEC
IC765_05020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC765_05020	COG0616	signal peptide processing
IC765_05025	COG0596	Alpha beta hydrolase
IC765_05030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC765_05090	COG2885	chlorophyll binding
IC765_05095	COG0823	Involved in the tonB-independent uptake of proteins
IC765_05115	COG0824	Thioesterase
IC765_05120	COG1473	amidohydrolase
IC765_05170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC765_05175	COG1024	Enoyl-CoA hydratase
IC765_05180	COG1056	cytidyltransferase-related domain
IC765_05180	COG1051	belongs to the nudix hydrolase family
IC765_05205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC765_05220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC765_05225	COG0602	queuosine metabolic process
IC765_05235	COG4625	pathogenesis
IC765_05240	COG0583	DNA-binding transcription factor activity
IC765_05245	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC765_05250	COG4208	sulfate ABC transporter
IC765_05255	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC765_05265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC765_05270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC765_05275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC765_05295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC765_05305	COG0481	GTPase activity
IC765_05310	COG0681	Belongs to the peptidase S26 family
IC765_05325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC765_05340	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC765_05350	COG4221	oxidoreductase activity
IC765_05375	COG0436	Aminotransferase
IC765_05395	COG3706	GGDEF domain
IC765_05510	COG1252	NADH dehydrogenase
IC765_05530	COG1187	pseudouridine synthase activity
IC765_05555	COG0477	Major facilitator Superfamily
IC765_05560	COG0583	DNA-binding transcription factor activity
IC765_05565	COG1823	symporter activity
IC765_05575	COG0612	Peptidase, M16
IC765_05635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC765_05650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC765_05655	COG0076	glutamate decarboxylase activity
IC765_05665	COG1522	sequence-specific DNA binding
IC765_05670	COG3961	Belongs to the TPP enzyme family
IC765_05675	COG1113	amino acid transport
IC765_05680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC765_05685	COG0573	inorganic phosphate transmembrane transporter activity
IC765_05695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC765_05700	COG0616	signal peptide processing
IC765_05800	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC765_05815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC765_05820	COG1966	Carbon starvation protein
IC765_05870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC765_05895	COG1741	Belongs to the pirin family
IC765_05930	COG0302	gtp cyclohydrolase
IC765_05940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC765_05965	COG0512	Glutamine amidotransferase of anthranilate synthase
IC765_05980	COG0174	glutamine synthetase
IC765_05990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC765_06025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC765_06030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC765_06035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC765_06060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC765_06065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC765_06085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC765_06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC765_06100	COG2223	nitrite transmembrane transporter activity
IC765_06110	COG0024	Methionine aminopeptidase
IC765_06115	COG0052	Belongs to the universal ribosomal protein uS2 family
IC765_06130	COG2207	Transcriptional regulator
IC765_06155	COG2951	lytic endotransglycosylase activity
IC765_06160	COG0772	Belongs to the SEDS family
IC765_06175	COG0842	Transport permease protein
IC765_06180	COG1131	(ABC) transporter
IC765_06185	COG0582	viral genome integration into host DNA
IC765_06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_06525	COG4215	(ABC) transporter
IC765_06530	COG4160	amino acid transport
IC765_06535	COG4598	ABC transporter
IC765_06545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC765_06555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC765_06580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IC765_06620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC765_06625	COG3139	Protein of unknown function (DUF1315)
IC765_06635	COG1301	dicarboxylic acid transport
IC765_06640	COG1960	acyl-CoA dehydrogenase activity
IC765_06660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC765_06670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC765_06675	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC765_06700	COG1234	tRNA 3'-trailer cleavage
IC765_06705	COG4650	regulator
IC765_06730	COG2363	Small membrane protein
IC765_06750	COG0513	Belongs to the DEAD box helicase family
IC765_06760	COG0778	Nitroreductase
IC765_06820	COG1610	YqeY-like protein
IC765_06850	COG2815	serine threonine protein kinase
IC765_06850	COG0515	serine threonine protein kinase
IC765_06875	COG2831	hemolysin activation secretion protein
IC765_06945	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IC765_07045	COG0786	glutamate:sodium symporter activity
IC765_07050	COG0475	glutathione-regulated potassium exporter activity
IC765_07050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC765_07055	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_07115	COG1309	transcriptional regulator
IC765_07125	COG2169	Transcriptional regulator
IC765_07125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC765_07165	COG2995	paraquat-inducible protein a
IC765_07180	COG2351	hydroxyisourate hydrolase activity
IC765_07195	COG5002	protein histidine kinase activity
IC765_07220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC765_07230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC765_07235	COG0642	Histidine kinase
IC765_07240	COG0745	RESPONSE REGULATOR receiver
IC765_07260	COG1794	racemase activity, acting on amino acids and derivatives
IC765_07300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC765_07305	COG2011	ABC-type metal ion transport system permease component
IC765_07310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC765_07315	COG1464	Belongs to the NlpA lipoprotein family
IC765_07320	COG0151	Belongs to the GarS family
IC765_07325	COG0138	bifunctional purine biosynthesis protein purh
IC765_07330	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC765_07360	COG2308	Evidence 4 Homologs of previously reported genes of
IC765_07370	COG1305	Transglutaminase-like
IC765_07410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC765_07420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC765_07450	COG0726	polysaccharide deacetylase
IC765_07450	COG1649	PFAM Uncharacterised BCR, COG1649
IC765_07455	COG1215	transferase activity, transferring glycosyl groups
IC765_07460	COG3658	cytochrome
IC765_07505	COG1960	acyl-CoA dehydrogenase activity
IC765_07515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC765_07540	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC765_07550	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC765_07555	COG2205	protein histidine kinase activity
IC765_07560	COG0745	RESPONSE REGULATOR receiver
IC765_07565	COG0174	glutamine synthetase
IC765_07580	COG0477	Major facilitator Superfamily
IC765_07620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC765_07635	COG0583	DNA-binding transcription factor activity
IC765_07650	COG1187	pseudouridine synthase activity
IC765_07675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC765_07685	COG1923	regulation of RNA biosynthetic process
IC765_07690	COG0697	spore germination
IC765_07715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC765_07720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC765_07720	COG0519	Catalyzes the synthesis of GMP from XMP
IC765_07725	COG4302	ethanolamine ammonia-lyase activity
IC765_07730	COG4303	Ethanolamine ammonia lyase large subunit
IC765_07735	COG0531	amino acid
IC765_07770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC765_07815	COG0625	glutathione transferase activity
IC765_07840	COG1280	lysine exporter protein (LysE YggA)
IC765_07865	COG2801	Transposase and inactivated derivatives
IC765_07905	COG4264	IucA IucC family
IC765_07910	COG2423	ornithine cyclodeaminase activity
IC765_07925	COG0668	transmembrane transport
IC765_07980	COG0488	(ABC) transporter
IC765_07985	COG0589	response to stress
IC765_08015	COG3135	benzoate transporter
IC765_08020	COG1522	sequence-specific DNA binding
IC765_08035	COG0583	DNA-binding transcription factor activity
IC765_08045	COG0183	Belongs to the thiolase family
IC765_08055	COG2030	dehydratase
IC765_08085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC765_08095	COG0824	Thioesterase
IC765_08100	COG1454	alcohol dehydrogenase
IC765_08125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC765_08155	COG0069	glutamate synthase activity
IC765_08210	COG0511	ligase activity, forming carbon-carbon bonds
IC765_08225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC765_08225	COG1116	anion transmembrane transporter activity
IC765_08240	COG2146	nitrite reductase [NAD(P)H] activity
IC765_08240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC765_08245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC765_08250	COG0243	molybdopterin cofactor binding
IC765_08280	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC765_08280	COG0315	cyclic pyranopterin monophosphate synthase activity
IC765_08285	COG0303	'Molybdopterin
IC765_08320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC765_08325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC765_08385	COG3852	Histidine kinase
IC765_08405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC765_08410	COG0575	Belongs to the CDS family
IC765_08425	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC765_08445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC765_08460	COG2137	regulation of response to DNA damage stimulus
IC765_08470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC765_08475	COG1011	Hydrolase
IC765_08490	COG1522	sequence-specific DNA binding
IC765_08590	COG0024	Methionine aminopeptidase
IC765_08595	COG0583	DNA-binding transcription factor activity
IC765_08605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC765_08610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC765_08615	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC765_08640	COG0552	protein localization to endoplasmic reticulum
IC765_08665	COG4890	Cyd operon protein YbgT
IC765_08685	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC765_08695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC765_08720	COG0569	domain protein
IC765_08725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC765_08755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC765_08760	COG0542	response to heat
IC765_08825	COG0148	phosphopyruvate hydratase activity
IC765_08840	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC765_08850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC765_08855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC765_08860	COG0183	Belongs to the thiolase family
IC765_08865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC765_08875	COG2271	Major facilitator Superfamily
IC765_08880	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC765_08890	COG3485	protocatechuate 3,4-dioxygenase
IC765_08895	COG0710	3-dehydroquinate dehydratase activity
IC765_08900	COG3420	alginic acid biosynthetic process
IC765_08905	COG3659	wide pore channel activity
IC765_08910	COG4993	Dehydrogenase
IC765_08920	COG2391	methyltransferase activity
IC765_08935	COG1414	Transcriptional regulator
IC765_08940	COG0583	DNA-binding transcription factor activity
IC765_08945	COG1960	acyl-CoA dehydrogenase activity
IC765_08970	COG2814	Major facilitator Superfamily
IC765_08980	COG0154	amidase activity
IC765_09000	COG4638	Rieske (2fe-2S)
IC765_09010	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_09020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC765_09030	COG3733	amine oxidase
IC765_09040	COG1012	belongs to the aldehyde dehydrogenase family
IC765_09045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC765_09050	COG0183	Belongs to the thiolase family
IC765_09055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC765_09060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC765_09070	COG4829	muconolactone delta-isomerase
IC765_09075	COG4948	Mandelate Racemase Muconate Lactonizing
IC765_09080	COG0583	DNA-binding transcription factor activity
IC765_09095	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IC765_09115	COG0583	DNA-binding transcription factor activity
IC765_09125	COG4638	Rieske (2fe-2S)
IC765_09130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC765_09145	COG3384	dioxygenase
IC765_09155	COG2814	Major facilitator Superfamily
IC765_09160	COG2814	Major facilitator Superfamily
IC765_09165	COG0583	DNA-binding transcription factor activity
IC765_09195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC765_09235	COG1309	transcriptional regulator
IC765_09240	COG4774	siderophore transport
IC765_09255	COG4689	acetoacetate decarboxylase
IC765_09310	COG1566	PFAM secretion protein HlyD family protein
IC765_09340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC765_09345	COG1120	ATPase activity
IC765_09365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC765_09455	COG2207	Transcriptional regulator
IC765_09460	COG1073	alpha beta
IC765_09465	COG1902	pentaerythritol trinitrate reductase activity
IC765_09470	COG2207	Transcriptional regulator
IC765_09515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC765_09530	COG5002	protein histidine kinase activity
IC765_09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC765_09560	COG3539	Fimbrial protein
IC765_09585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC765_09605	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC765_09610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC765_09620	COG2205	protein histidine kinase activity
IC765_09625	COG0745	RESPONSE REGULATOR receiver
IC765_09630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_09635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC765_09695	COG4771	TonB-dependent receptor
IC765_09700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC765_09720	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_09730	COG3251	PFAM MbtH domain protein
IC765_09760	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC765_09765	COG4149	molybdate abc transporter
IC765_09770	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC765_09780	COG4638	Rieske (2fe-2S)
IC765_09785	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC765_09790	COG0543	2 iron, 2 sulfur cluster binding
IC765_09790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC765_09805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC765_09815	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_09835	COG2207	Transcriptional regulator
IC765_09840	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_09845	COG2610	gluconate transmembrane transporter activity
IC765_09850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC765_09875	COG0583	DNA-binding transcription factor activity
IC765_09890	COG2031	fatty acid transporter
IC765_09900	COG0583	DNA-binding transcription factor activity
IC765_09905	COG0583	DNA-binding transcription factor activity
IC765_09935	COG0477	Major facilitator Superfamily
IC765_09945	COG1609	Transcriptional regulator
IC765_09945	COG2207	Transcriptional regulator
IC765_09985	COG3781	membrane
IC765_09990	COG1063	alcohol dehydrogenase
IC765_10000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC765_10005	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC765_10010	COG0022	dehydrogenase e1 component
IC765_10015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC765_10025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC765_10055	COG0133	tryptophan synthase activity
IC765_10065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC765_10105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC765_10130	COG2226	methyltransferase
IC765_10180	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC765_10185	COG4773	Receptor
IC765_10200	COG0730	response to heat
IC765_10205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC765_10225	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC765_10240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC765_10245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC765_10260	COG1960	acyl-CoA dehydrogenase activity
IC765_10270	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC765_10275	COG2207	Transcriptional regulator
IC765_10280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC765_10285	COG0776	regulation of translation
IC765_10310	COG0822	iron-sulfur transferase activity
IC765_10315	COG0316	Belongs to the HesB IscA family
IC765_10345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC765_10365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC765_10370	COG0702	epimerase
IC765_10405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC765_10415	COG0339	signal peptide processing
IC765_10465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC765_10470	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC765_10485	COG2431	L-lysine efflux transmembrane transporter activity
IC765_10500	COG0776	regulation of translation
IC765_10565	COG0084	hydrolase, TatD family'
IC765_10590	COG1132	(ABC) transporter
IC765_10600	COG0811	peptide transport
IC765_10605	COG1475	DNA binding
IC765_10610	COG1192	Involved in chromosome partitioning
IC765_10620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC765_10635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC765_10660	COG0424	maF-like protein
IC765_10665	COG2850	peptidyl-arginine hydroxylation
IC765_10675	COG0640	Transcriptional regulator
IC765_10685	COG3619	membrane
IC765_10690	COG3122	Protein conserved in bacteria
IC765_10715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC765_10730	COG0506	proline dehydrogenase activity
IC765_10730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC765_10730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC765_10735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC765_10750	COG3698	Phosphodiester glycosidase
IC765_10760	COG2353	YceI-like domain
IC765_10775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC765_10905	COG2197	response regulator
IC765_10940	COG1126	abc transporter atp-binding protein
IC765_10950	COG0765	amino acid transport
IC765_10990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC765_10995	COG2011	ABC-type metal ion transport system permease component
IC765_11000	COG0012	GTP binding
IC765_11025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC765_11075	COG0436	Aminotransferase
IC765_11080	COG1301	dicarboxylic acid transport
IC765_11115	COG3634	alkyl hydroperoxide reductase activity
IC765_11135	COG0431	NADPH-dependent FMN reductase
IC765_11140	COG0798	PFAM Bile acid sodium symporter
IC765_11145	COG0640	Transcriptional regulator
IC765_11170	COG0583	DNA-binding transcription factor activity
IC765_11180	COG1953	Uracil, thiamine, allantoin
IC765_11190	COG2175	clavaminate synthase activity
IC765_11195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC765_11200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC765_11215	COG0477	Major facilitator Superfamily
IC765_11245	COG1294	oxidase, subunit
IC765_11255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC765_11275	COG1346	cytolysis
IC765_11285	COG0583	DNA-binding transcription factor activity
IC765_11290	COG0625	glutathione transferase activity
IC765_11295	COG0625	glutathione transferase activity
IC765_11315	COG0583	DNA-binding transcription factor activity
IC765_11320	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_11330	COG1045	serine acetyltransferase
IC765_11335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC765_11340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC765_11345	COG1280	lysine exporter protein (LysE YggA)
IC765_11360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC765_11365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC765_11375	COG0765	amino acid transport
IC765_11380	COG0765	amino acid transport
IC765_11470	COG0583	DNA-binding transcription factor activity
IC765_11480	COG2814	Major facilitator Superfamily
IC765_11495	COG0318	PFAM AMP-dependent synthetase and ligase
IC765_11500	COG1309	transcriptional regulator
IC765_11505	COG1960	acyl-CoA dehydrogenase activity
IC765_11510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC765_11515	COG1024	Enoyl-CoA hydratase
IC765_11520	COG4770	biotin carboxylase activity
IC765_11545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC765_11565	COG3842	ATPase activity
IC765_11595	COG1414	Transcriptional regulator
IC765_11605	COG0583	DNA-binding transcription factor activity
IC765_11610	COG1309	transcriptional regulator
IC765_11620	COG2801	Transposase and inactivated derivatives
IC765_11625	COG1073	alpha beta
IC765_11630	COG1073	alpha beta
IC765_11640	COG0531	amino acid
IC765_11645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC765_11660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC765_11680	COG2801	Transposase and inactivated derivatives
IC765_11710	COG0406	alpha-ribazole phosphatase activity
IC765_11720	COG2050	protein possibly involved in aromatic compounds catabolism
IC765_11740	COG0183	Belongs to the thiolase family
IC765_11745	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC765_11750	COG1024	Enoyl-CoA hydratase
IC765_11760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC765_11765	COG0633	Ferredoxin
IC765_11765	COG0543	2 iron, 2 sulfur cluster binding
IC765_11770	COG2151	metal-sulfur cluster biosynthetic enzyme
IC765_11775	COG3396	Phenylacetate-CoA oxygenase
IC765_11780	COG3460	Phenylacetate-CoA oxygenase
IC765_11785	COG3396	Phenylacetate-CoA oxygenase
IC765_11795	COG1760	l-serine dehydratase
IC765_11810	COG0789	Transcriptional regulator
IC765_11845	COG0590	tRNA wobble adenosine to inosine editing
IC765_11890	COG2885	chlorophyll binding
IC765_11925	COG1733	regulation of RNA biosynthetic process
IC765_11930	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC765_11985	COG4770	biotin carboxylase activity
IC765_12005	COG1914	H( )-stimulated, divalent metal cation uptake system
IC765_12010	COG0583	DNA-binding transcription factor activity
IC765_12020	COG1595	DNA-templated transcription, initiation
IC765_12030	COG3220	belongs to the UPF0276 family
IC765_12045	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_12060	COG2076	Multidrug Resistance protein
IC765_12075	COG3713	MltA-interacting MipA family protein
IC765_12080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC765_12155	COG2801	Transposase and inactivated derivatives
IC765_12205	COG1309	transcriptional regulator
IC765_12210	COG1278	Cold shock
IC765_12225	COG0626	cystathionine gamma-synthase activity
IC765_12230	COG1522	sequence-specific DNA binding
IC765_12250	COG2814	Major facilitator Superfamily
IC765_12265	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
IC765_12285	COG1271	oxidase subunit
IC765_12300	COG1469	GTP cyclohydrolase I activity
IC765_12320	COG1560	Kdo2-lipid A biosynthetic process
IC765_12375	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC765_12385	COG4122	O-methyltransferase activity
IC765_12415	COG1538	Outer membrane efflux protein
IC765_12420	COG1137	ATPase activity
IC765_12425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC765_12435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC765_12470	COG0667	Aldo Keto reductase
IC765_12480	COG2814	Major facilitator Superfamily
IC765_12510	COG1278	Cold shock
IC765_12515	COG1280	lysine exporter protein (LysE YggA)
IC765_12635	COG2871	sodium ion transport
IC765_12645	COG0583	DNA-binding transcription factor activity
IC765_12655	COG4638	Rieske (2fe-2S)
IC765_12660	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC765_12665	COG0633	Ferredoxin
IC765_12665	COG0543	2 iron, 2 sulfur cluster binding
IC765_12670	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_12675	COG3135	benzoate transporter
IC765_12710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC765_12730	COG3634	alkyl hydroperoxide reductase activity
IC765_12750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC765_12755	COG0625	glutathione transferase activity
IC765_12800	COG0542	response to heat
IC765_12820	COG1765	OsmC-like protein
IC765_12830	COG0667	Aldo Keto reductase
IC765_12860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC765_12880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC765_12900	COG2252	PERMEase
IC765_12925	COG1741	Belongs to the pirin family
IC765_12930	COG1309	transcriptional regulator
IC765_12945	COG2072	flavoprotein involved in K transport
IC765_12950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC765_13015	COG2814	Major facilitator Superfamily
IC765_13025	COG1012	belongs to the aldehyde dehydrogenase family
IC765_13060	COG0697	spore germination
IC765_13080	COG1113	amino acid transport
IC765_13100	COG1012	belongs to the aldehyde dehydrogenase family
IC765_13120	COG0531	amino acid
IC765_13220	COG2801	Transposase and inactivated derivatives
IC765_13280	COG0251	oxidation-reduction process
IC765_13305	COG5001	Diguanylate cyclase
IC765_13305	COG4251	negative regulation of phosphorylation
IC765_13305	COG3706	GGDEF domain
IC765_13305	COG2203	Gaf domain
IC765_13315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC765_13345	COG4172	Belongs to the ABC transporter superfamily
IC765_13355	COG4174	ABC transporter (Permease)
IC765_13360	COG4166	transmembrane transport
IC765_13365	COG0741	lytic transglycosylase activity
IC765_13365	COG1388	LysM domain
IC765_13365	COG1388	LysM domain
IC765_13365	COG0741	lytic transglycosylase activity
IC765_13410	COG0583	DNA-binding transcription factor activity
IC765_13415	COG1279	arginine transmembrane transporter activity
IC765_13435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC765_13440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC765_13445	COG0006	proline dipeptidase activity
IC765_13480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC765_13560	COG3384	dioxygenase
IC765_13575	COG2878	Part of a membrane complex involved in electron transport
IC765_13580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC765_13605	COG0768	penicillin binding
IC765_13610	COG0742	ribosomal rna small subunit methyltransferase
IC765_13630	COG0830	nickel cation binding
IC765_13680	COG1253	flavin adenine dinucleotide binding
IC765_13685	COG2851	Citrate transporter
IC765_13735	COG1773	rubredoxin
IC765_13740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC765_13825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC765_13845	COG0306	phosphate transporter
IC765_13875	COG2223	nitrite transmembrane transporter activity
IC765_13880	COG2207	Transcriptional regulator
IC765_13890	COG0242	peptide deformylase activity
IC765_13895	COG0477	Major facilitator Superfamily
IC765_13925	COG2267	carboxylic ester hydrolase activity
IC765_13950	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_13965	COG2146	nitrite reductase [NAD(P)H] activity
IC765_13970	COG1414	Transcriptional regulator
IC765_14000	COG1024	Enoyl-CoA hydratase
IC765_14015	COG1649	PFAM Uncharacterised BCR, COG1649
IC765_14015	COG0726	polysaccharide deacetylase
IC765_14045	COG1607	acyl-coa hydrolase
IC765_14055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC765_14060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC765_14065	COG1309	transcriptional regulator
IC765_14090	COG2040	homocysteine
IC765_14150	COG1595	DNA-templated transcription, initiation
IC765_14160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC765_14260	COG2814	Major facilitator Superfamily
IC765_14270	COG2050	protein possibly involved in aromatic compounds catabolism
IC765_14285	COG1090	epimerase
IC765_14305	COG0420	3'-5' exonuclease activity
IC765_14315	COG1968	undecaprenyl-diphosphatase activity
IC765_14335	COG0735	belongs to the Fur family
IC765_14340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC765_14360	COG0121	glutamine amidotransferase
IC765_14375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC765_14390	COG2885	chlorophyll binding
IC765_14410	COG2894	cell division
IC765_14430	COG1674	ftsk spoiiie
IC765_14435	COG0492	ferredoxin-NADP+ reductase activity
IC765_14440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC765_14450	COG0456	acetyltransferase
IC765_14470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC765_14480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC765_14495	COG1981	membrane
IC765_14505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC765_14505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC765_14540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC765_14590	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC765_14620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC765_14650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC765_14660	COG0351	phosphomethylpyrimidine kinase
IC765_14660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC765_14660	COG0352	thiamine-phosphate diphosphorylase activity
IC765_14665	COG1652	LysM domain
IC765_14690	COG1399	metal-binding, possibly nucleic acid-binding protein
IC765_14700	COG0009	L-threonylcarbamoyladenylate synthase
IC765_14705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC765_14710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC765_14745	COG1877	trehalose-phosphatase activity
IC765_14785	COG0730	response to heat
IC765_14800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC765_14855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC765_14860	COG0489	protein tyrosine kinase activity
IC765_14870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC765_14870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC765_14905	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC765_14910	COG2081	HI0933 family
IC765_14920	COG0668	transmembrane transport
IC765_14940	COG0583	DNA-binding transcription factor activity
IC765_14965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC765_14985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC765_15040	COG0745	RESPONSE REGULATOR receiver
IC765_15060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC765_15095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC765_15100	COG0583	DNA-binding transcription factor activity
IC765_15170	COG0583	DNA-binding transcription factor activity
IC765_15225	COG1309	transcriptional regulator
IC765_15235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC765_15245	COG1960	acyl-CoA dehydrogenase activity
IC765_15250	COG0583	DNA-binding transcription factor activity
IC765_15255	COG1063	alcohol dehydrogenase
IC765_15290	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC765_15295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC765_15325	COG0561	phosphatase activity
IC765_15330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC765_15340	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC765_15355	COG1214	PFAM Peptidase M22, glycoprotease
IC765_15415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC765_15420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC765_15425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC765_15485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC765_15495	COG1846	Transcriptional regulator
IC765_15500	COG1764	response to oxidative stress
IC765_15540	COG0037	tRNA processing
IC765_15550	COG0248	Ppx GppA phosphatase
IC765_15580	COG0072	phenylalanine-tRNA ligase activity
IC765_15610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC765_15620	COG1238	metal cluster binding
IC765_15640	COG0318	PFAM AMP-dependent synthetase and ligase
IC765_15645	COG3028	Belongs to the UPF0307 family
IC765_15670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC765_15715	COG2205	protein histidine kinase activity
IC765_15715	COG5002	protein histidine kinase activity
IC765_15715	COG0784	Response regulator, receiver
IC765_15720	COG1024	Enoyl-CoA hydratase
IC765_15725	COG2084	Dehydrogenase
IC765_15730	COG3622	Belongs to the hyi family
IC765_15770	COG2814	Major facilitator Superfamily
IC765_15775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC765_15785	COG0583	DNA-binding transcription factor activity
IC765_15795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC765_15810	COG0084	hydrolase, TatD family'
IC765_15825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC765_15855	COG0440	acetolactate synthase activity
IC765_15860	COG0028	Belongs to the TPP enzyme family
IC765_15885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC765_15890	COG0577	efflux transmembrane transporter activity
IC765_15890	COG1136	(ABC) transporter
IC765_15910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC765_15925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC765_15950	COG1028	Short-chain dehydrogenase reductase Sdr
IC765_15990	COG2986	histidine ammonia-lyase
IC765_16000	COG1216	Glycosyl transferase, family 2
IC765_16060	COG1426	Protein conserved in bacteria
IC765_16120	COG1012	belongs to the aldehyde dehydrogenase family
IC765_16125	COG3265	gluconokinase activity
IC765_16175	COG0740	serine-type endopeptidase activity
IC765_16185	COG4774	siderophore transport
IC765_16195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC765_16205	COG2813	Specifically methylates the guanine in position
IC765_16205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC765_16300	COG0788	formyltetrahydrofolate deformylase activity
IC765_16325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC765_16325	COG4651	solute:proton antiporter activity
IC765_16345	COG0724	RNA recognition motif
IC765_16380	COG1733	regulation of RNA biosynthetic process
IC765_16385	COG0604	alcohol dehydrogenase
IC765_16390	COG2900	Belongs to the SlyX family
IC765_16395	COG0488	(ABC) transporter
IC765_16405	COG1280	lysine exporter protein (LysE YggA)
IC765_16420	COG1301	dicarboxylic acid transport
IC765_16475	COG0473	3-isopropylmalate dehydrogenase activity
IC765_16565	COG0625	glutathione transferase activity
IC765_16570	COG2378	regulation of single-species biofilm formation
IC765_16585	COG1530	ribonuclease E activity
IC765_16605	COG0583	DNA-binding transcription factor activity
IC765_16610	COG4221	oxidoreductase activity
IC765_16625	COG0534	Mate efflux family protein
IC765_16640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC765_16675	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC765_16695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC765_16705	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC765_16705	COG0644	oxidoreductase
IC765_16720	COG4535	Mg2 and Co2 transporter CorC
IC765_16730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC765_16760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC765_16760	COG0475	glutathione-regulated potassium exporter activity
IC765_16775	COG0484	heat shock protein binding
IC765_16780	COG0789	Transcriptional regulator
IC765_16785	COG0598	Magnesium transport protein CorA
IC765_16790	COG1185	polyribonucleotide nucleotidyltransferase activity
IC765_16805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC765_16815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC765_16840	COG2226	methyltransferase
IC765_16860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC765_16885	COG0651	ATP synthesis coupled electron transport
IC765_16890	COG1863	multisubunit Na H antiporter MnhE subunit
IC765_16895	COG2212	antiporter activity
IC765_16900	COG1320	monovalent cation:proton antiporter activity
IC765_16905	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC765_16955	COG0237	dephospho-CoA kinase activity
IC765_16965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC765_16990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC765_17005	COG1289	transmembrane transporter activity
IC765_17020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC765_17080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC765_17095	COG0326	Molecular chaperone. Has ATPase activity
IC765_17110	COG2056	Na+-H+ antiporter family
IC765_17210	COG0546	phosphoglycolate phosphatase activity
IC765_17215	COG1716	ATPase activity
IC765_17270	COG3275	phosphorelay sensor kinase activity
IC765_17290	COG1538	Outer membrane efflux protein
IC765_17295	COG0697	spore germination
IC765_17325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC765_17335	COG0772	Belongs to the SEDS family
IC765_17360	COG4974	Belongs to the 'phage' integrase family
IC765_17365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC765_17375	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC765_17385	COG2197	response regulator
IC765_17400	COG0793	Belongs to the peptidase S41A family
IC765_17410	COG0795	lipopolysaccharide-transporting ATPase activity
IC765_17415	COG0795	lipopolysaccharide-transporting ATPase activity
IC765_17450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC765_17450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC765_17465	COG0347	Belongs to the P(II) protein family
IC765_17475	COG0606	chelatase, subunit chli
IC765_17505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC765_17530	COG0477	Major facilitator Superfamily
IC765_17535	COG2860	membrane
IC765_17545	COG1253	flavin adenine dinucleotide binding
IC765_17565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC765_17570	COG0745	RESPONSE REGULATOR receiver
IC765_17575	COG2205	protein histidine kinase activity
IC765_17580	COG4452	Inner membrane protein CreD
IC765_17620	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC765_17670	COG1309	transcriptional regulator
IC765_17705	COG0758	DNA mediated transformation
IC765_17715	COG0697	spore germination
IC765_17720	COG1309	transcriptional regulator
IC765_17735	COG0386	Belongs to the glutathione peroxidase family
IC765_17745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC765_17800	COG1121	(ABC) transporter
IC765_17805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC765_17810	COG1280	lysine exporter protein (LysE YggA)
IC765_17815	COG2837	iron assimilation
IC765_17825	COG0281	malic enzyme
IC765_17860	COG0735	belongs to the Fur family
IC765_17870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC765_17880	COG4399	Belongs to the UPF0754 family
IC765_17880	COG4399	Belongs to the UPF0754 family
IC765_17885	COG2259	Doxx family
IC765_17890	COG0586	Pfam SNARE associated Golgi protein
IC765_17905	COG1192	Involved in chromosome partitioning
IC765_17955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC765_17955	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC765_17955	COG3321	synthase
IC765_17955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC765_17970	COG2197	response regulator
IC765_17995	COG1024	Enoyl-CoA hydratase
IC765_18000	COG1024	Enoyl-CoA hydratase
IC765_18005	COG1960	acyl-CoA dehydrogenase activity
IC765_18080	COG0564	pseudouridine synthase activity
IC765_18115	COG2801	Transposase and inactivated derivatives
IC765_18150	COG1051	belongs to the nudix hydrolase family
IC765_18200	COG1802	Transcriptional regulator
IC765_18210	COG1448	Aminotransferase
IC765_18215	COG0277	FAD linked oxidase domain protein
IC765_18235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC765_18245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC765_18265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC765_18280	COG0110	maltose O-acetyltransferase activity
IC765_18285	COG0463	Glycosyl transferase, family 2
IC765_18310	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC765_18315	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC765_18325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC765_18330	COG1596	polysaccharide export
IC765_18360	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC765_18415	COG0546	phosphoglycolate phosphatase activity
IC765_18435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC765_18435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC765_18440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC765_18445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC765_18450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC765_18455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC765_18460	COG1116	anion transmembrane transporter activity
IC765_18465	COG1309	transcriptional regulator
IC765_18470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC765_18480	COG0196	riboflavin kinase activity
IC765_18495	COG1047	Peptidyl-prolyl cis-trans
IC765_18540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC765_18545	COG0657	acetylesterase activity
IC765_18600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC765_18625	COG0671	phosphoesterase, PA-phosphatase related
IC765_18630	COG0861	Integral membrane protein TerC family
IC765_18645	COG0402	S-adenosylhomocysteine deaminase activity
IC765_18660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC765_18920	COG2132	Multicopper oxidase
IC765_18935	COG2205	protein histidine kinase activity
IC765_19100	COG0582	viral genome integration into host DNA
IC765_19120	COG1309	transcriptional regulator
IC765_19185	COG0477	Major facilitator Superfamily
IC765_19190	COG0697	spore germination
IC765_19200	COG3321	synthase
IC765_19200	COG0604	alcohol dehydrogenase
IC765_19205	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC765_19215	COG4221	oxidoreductase activity
IC765_19250	COG3077	Addiction module antitoxin, RelB DinJ family
IC765_19265	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC765_19290	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC765_19325	COG2184	nucleotidyltransferase activity
IC765_19360	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC765_19570	COG0582	viral genome integration into host DNA
IC765_19720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC765_19730	COG1846	Transcriptional regulator
IC765_19785	COG1192	Involved in chromosome partitioning
IC765_19825	COG0477	Major facilitator Superfamily
IC765_19830	COG0697	spore germination
IC765_19945	COG3706	GGDEF domain