locus-tag	class	description
IC766_00010	COG0592	DNA-directed DNA polymerase activity
IC766_00020	COG0187	DNA topoisomerase II activity
IC766_00030	COG0586	Pfam SNARE associated Golgi protein
IC766_00035	COG0488	(ABC) transporter
IC766_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC766_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC766_00100	COG0625	glutathione transferase activity
IC766_00110	COG0733	neurotransmitter:sodium symporter activity
IC766_00150	COG2233	PERMEase
IC766_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_00200	COG2814	Major facilitator Superfamily
IC766_00205	COG0656	L-ascorbic acid biosynthetic process
IC766_00210	COG0583	DNA-binding transcription factor activity
IC766_00230	COG1064	alcohol dehydrogenase
IC766_00235	COG2818	Glycosylase
IC766_00250	COG1194	a g-specific adenine glycosylase
IC766_00265	COG5487	UPF0391 membrane protein
IC766_00270	COG2983	Belongs to the UPF0260 family
IC766_00275	COG2133	pyrroloquinoline quinone binding
IC766_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC766_00285	COG2116	formate transmembrane transporter activity
IC766_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC766_00310	COG1335	isochorismatase
IC766_00315	COG0385	Bile acid
IC766_00320	COG0534	Mate efflux family protein
IC766_00325	COG1683	Conserved Protein
IC766_00340	COG0346	lactoylglutathione lyase activity
IC766_00345	COG0625	glutathione transferase activity
IC766_00355	COG1113	amino acid transport
IC766_00365	COG0523	cobalamin synthesis protein
IC766_00375	COG2188	Transcriptional regulator
IC766_00405	COG0010	Belongs to the arginase family
IC766_00415	COG0546	phosphoglycolate phosphatase activity
IC766_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC766_00425	COG1280	lysine exporter protein (LysE YggA)
IC766_00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC766_00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC766_00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC766_00565	COG0534	Mate efflux family protein
IC766_00570	COG0436	Aminotransferase
IC766_00575	COG2733	membrane
IC766_00590	COG2918	glutathione biosynthetic process
IC766_00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC766_00605	COG1388	LysM domain
IC766_00645	COG3150	esterase
IC766_00655	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IC766_00675	COG2233	PERMEase
IC766_00680	COG2351	hydroxyisourate hydrolase activity
IC766_00700	COG0666	response to abiotic stimulus
IC766_00700	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC766_00715	COG3706	GGDEF domain
IC766_00730	COG1393	Belongs to the ArsC family
IC766_00735	COG0708	Exodeoxyribonuclease III
IC766_00760	COG0189	ligase activity
IC766_00780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IC766_00790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IC766_00805	COG4942	peptidase
IC766_00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC766_00825	COG2119	membrane
IC766_00830	COG0426	domain, Protein
IC766_00830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC766_00855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IC766_00875	COG1902	pentaerythritol trinitrate reductase activity
IC766_00880	COG1519	Transferase
IC766_00885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC766_00890	COG0668	transmembrane transport
IC766_00900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC766_00905	COG1335	isochorismatase
IC766_00910	COG1522	sequence-specific DNA binding
IC766_00935	COG2205	protein histidine kinase activity
IC766_00935	COG0784	Response regulator, receiver
IC766_00935	COG2198	Histidine kinase
IC766_00940	COG3162	membrane
IC766_00945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC766_00955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC766_00975	COG1309	transcriptional regulator
IC766_00995	COG4221	oxidoreductase activity
IC766_01005	COG0351	phosphomethylpyrimidine kinase
IC766_01005	COG0352	thiamine-phosphate diphosphorylase activity
IC766_01005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC766_01015	COG2814	Major facilitator Superfamily
IC766_01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC766_01040	COG1113	amino acid transport
IC766_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC766_01055	COG1012	belongs to the aldehyde dehydrogenase family
IC766_01065	COG1335	isochorismatase
IC766_01100	COG2814	Major facilitator Superfamily
IC766_01105	COG0583	DNA-binding transcription factor activity
IC766_01125	COG0667	Aldo Keto reductase
IC766_01145	COG1733	regulation of RNA biosynthetic process
IC766_01170	COG1733	regulation of RNA biosynthetic process
IC766_01175	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC766_01240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC766_01285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC766_01315	COG0427	acetyl-CoA hydrolase
IC766_01345	COG0659	secondary active sulfate transmembrane transporter activity
IC766_01350	COG4221	oxidoreductase activity
IC766_01360	COG0028	Belongs to the TPP enzyme family
IC766_01365	COG0488	(ABC) transporter
IC766_01440	COG0833	amino acid
IC766_01485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC766_01490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IC766_01505	COG2226	methyltransferase
IC766_01555	COG0070	glutamate synthase
IC766_01555	COG0067	glutamate synthase
IC766_01555	COG0069	glutamate synthase activity
IC766_01560	COG0493	'glutamate synthase
IC766_01570	COG1704	LemA family
IC766_01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IC766_01585	COG4969	Belongs to the N-Me-Phe pilin family
IC766_01595	COG3307	-O-antigen
IC766_01615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC766_01630	COG0194	GDP metabolic process
IC766_01645	COG4969	Belongs to the N-Me-Phe pilin family
IC766_01670	COG4969	Belongs to the N-Me-Phe pilin family
IC766_01685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC766_01695	COG0335	large ribosomal subunit rRNA binding
IC766_01705	COG5380	lipid catabolic process
IC766_01710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC766_01730	COG5006	permease, DMT superfamily
IC766_01735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IC766_01740	COG0277	FAD linked oxidase domain protein
IC766_01750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC766_01755	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC766_01770	COG1289	transmembrane transporter activity
IC766_01780	COG0628	permease
IC766_01785	COG1192	Involved in chromosome partitioning
IC766_01815	COG0833	amino acid
IC766_01820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC766_01825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC766_01835	COG1012	belongs to the aldehyde dehydrogenase family
IC766_01875	COG0583	DNA-binding transcription factor activity
IC766_01880	COG1794	racemase activity, acting on amino acids and derivatives
IC766_01885	COG0583	DNA-binding transcription factor activity
IC766_01905	COG0752	glycyl-tRNA synthetase alpha subunit
IC766_01930	COG0517	IMP dehydrogenase activity
IC766_01935	COG1983	PspC domain protein
IC766_01945	COG1960	acyl-CoA dehydrogenase activity
IC766_01960	COG0408	coproporphyrinogen oxidase activity
IC766_01980	COG0513	Belongs to the DEAD box helicase family
IC766_01985	COG1127	ABC transporter
IC766_01990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC766_02000	COG2854	intermembrane phospholipid transfer
IC766_02010	COG0598	Magnesium transport protein CorA
IC766_02020	COG0494	nUDIX hydrolase
IC766_02025	COG1040	competence protein
IC766_02030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IC766_02045	COG2937	Belongs to the GPAT DAPAT family
IC766_02050	COG1946	Acyl-CoA thioesterase
IC766_02055	COG1301	dicarboxylic acid transport
IC766_02070	COG1959	2 iron, 2 sulfur cluster binding
IC766_02075	COG1017	nitric oxide dioxygenase activity
IC766_02075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC766_02080	COG0433	COG0433 Predicted ATPase
IC766_02085	COG0626	cystathionine gamma-synthase activity
IC766_02100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC766_02105	COG0088	Forms part of the polypeptide exit tunnel
IC766_02240	COG1960	acyl-CoA dehydrogenase activity
IC766_02245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC766_02275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IC766_02280	COG0339	signal peptide processing
IC766_02285	COG0557	exoribonuclease II activity
IC766_02330	COG0179	Fumarylacetoacetate (FAA) hydrolase
IC766_02335	COG2169	Transcriptional regulator
IC766_02345	COG1295	ribonuclease BN
IC766_02380	COG1702	phosphate starvation-inducible protein PhoH
IC766_02390	COG0741	lytic transglycosylase activity
IC766_02390	COG0739	heme binding
IC766_02390	COG1196	nuclear chromosome segregation
IC766_02420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC766_02425	COG1183	phosphatidylcholine synthase activity
IC766_02475	COG1960	acyl-CoA dehydrogenase activity
IC766_02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC766_02485	COG1309	transcriptional regulator
IC766_02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC766_02505	COG1960	acyl-CoA dehydrogenase activity
IC766_02510	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC766_02510	COG1024	Enoyl-CoA hydratase
IC766_02550	COG2969	positive regulation of protein catabolic process
IC766_02560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC766_02565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC766_02570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IC766_02575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IC766_02580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IC766_02600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC766_02610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC766_02615	COG1408	metallophosphoesterase
IC766_02625	COG2199	diguanylate cyclase activity
IC766_02660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC766_02685	COG1607	acyl-coa hydrolase
IC766_02720	COG2350	Protein conserved in bacteria
IC766_02730	COG0613	PHP domain protein
IC766_02735	COG3781	membrane
IC766_02745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC766_02750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC766_02760	COG1862	Preprotein translocase
IC766_02795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC766_02805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IC766_02820	COG2194	sulfuric ester hydrolase activity
IC766_02830	COG0726	polysaccharide deacetylase
IC766_02835	COG0463	Glycosyl transferase, family 2
IC766_02840	COG0438	transferase activity, transferring glycosyl groups
IC766_02880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC766_02915	COG1960	acyl-CoA dehydrogenase activity
IC766_02920	COG1960	acyl-CoA dehydrogenase activity
IC766_02930	COG2205	protein histidine kinase activity
IC766_02935	COG0745	RESPONSE REGULATOR receiver
IC766_02945	COG3328	transposase activity
IC766_02950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IC766_02970	COG2096	Adenosyltransferase
IC766_02975	COG4206	TonB-dependent receptor
IC766_03025	COG0285	dihydrofolate synthase activity
IC766_03045	COG0450	alkyl hydroperoxide reductase
IC766_03060	COG0477	Major facilitator Superfamily
IC766_03065	COG1272	protein, Hemolysin III
IC766_03075	COG2153	protein acetylation
IC766_03095	COG0183	Belongs to the thiolase family
IC766_03100	COG2207	Transcriptional regulator
IC766_03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC766_03135	COG0183	Belongs to the thiolase family
IC766_03145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IC766_03145	COG2885	chlorophyll binding
IC766_03155	COG1690	Belongs to the RtcB family
IC766_03160	COG0833	amino acid
IC766_03170	COG2233	PERMEase
IC766_03175	COG1217	gtp-binding protein TYPA
IC766_03200	COG2094	Belongs to the DNA glycosylase MPG family
IC766_03210	COG1902	pentaerythritol trinitrate reductase activity
IC766_03215	COG0679	Auxin Efflux Carrier
IC766_03225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC766_03230	COG0354	folic acid binding
IC766_03245	COG2233	PERMEase
IC766_03250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC766_03255	COG0251	oxidation-reduction process
IC766_03260	COG1335	isochorismatase
IC766_03265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_03275	COG0596	Alpha beta hydrolase
IC766_03280	COG3189	MarR family transcriptional regulator
IC766_03285	COG2824	Alkylphosphonate utilization operon protein PhnA
IC766_03290	COG3422	double-strand break repair
IC766_03330	COG0840	transmembrane signaling receptor activity
IC766_03345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC766_03370	COG2832	Protein of unknown function (DUF454)
IC766_03375	COG1376	ErfK ybiS ycfS ynhG family protein
IC766_03425	COG1289	transmembrane transporter activity
IC766_03430	COG2814	Major facilitator Superfamily
IC766_03450	COG1115	amino acid carrier protein
IC766_03455	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC766_03460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC766_03465	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IC766_03495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC766_03505	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IC766_03510	COG1077	Cell shape determining protein MreB Mrl
IC766_03515	COG1792	Involved in formation and maintenance of cell shape
IC766_03520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC766_03525	COG0424	maF-like protein
IC766_03530	COG1530	ribonuclease E activity
IC766_03540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC766_03560	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC766_03585	COG2207	Transcriptional regulator
IC766_03615	COG3046	protein related to deoxyribodipyrimidine photolyase
IC766_03620	COG2816	NAD+ diphosphatase activity
IC766_03625	COG1113	amino acid transport
IC766_03630	COG2828	Protein conserved in bacteria
IC766_03635	COG0142	geranyltranstransferase activity
IC766_03640	COG2315	Protein conserved in bacteria
IC766_03655	COG1752	Esterase of the alpha-beta hydrolase superfamily
IC766_03675	COG2194	sulfuric ester hydrolase activity
IC766_03680	COG0745	RESPONSE REGULATOR receiver
IC766_03685	COG0642	Histidine kinase
IC766_03695	COG0004	ammonium transporteR
IC766_03700	COG0583	DNA-binding transcription factor activity
IC766_03720	COG0525	valine-tRNA ligase activity
IC766_03730	COG0525	valine-tRNA ligase activity
IC766_03740	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_03750	COG0393	Putative heavy-metal-binding
IC766_03755	COG0393	Putative heavy-metal-binding
IC766_03760	COG1538	Outer membrane efflux protein
IC766_03770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_03775	COG0671	phosphoesterase, PA-phosphatase related
IC766_03805	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IC766_03820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC766_03820	COG1648	precorrin-2 dehydrogenase activity
IC766_03825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC766_03830	COG1733	regulation of RNA biosynthetic process
IC766_03840	COG0531	amino acid
IC766_03855	COG0321	lipoyl(octanoyl) transferase activity
IC766_03860	COG2921	Belongs to the UPF0250 family
IC766_03895	COG2009	succinate dehydrogenase
IC766_03900	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC766_03905	COG1053	succinate dehydrogenase
IC766_03910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC766_03935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC766_03955	COG2354	Protein conserved in bacteria
IC766_03960	COG2321	neutral zinc metallopeptidase
IC766_03980	COG2843	Capsule synthesis protein
IC766_04000	COG0589	response to stress
IC766_04020	COG0505	Belongs to the CarA family
IC766_04045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC766_04050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IC766_04100	COG0477	Major facilitator Superfamily
IC766_04105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IC766_04120	COG1597	lipid kinase activity
IC766_04125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IC766_04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC766_04150	COG0584	glycerophosphoryl diester phosphodiesterase
IC766_04170	COG0741	lytic transglycosylase activity
IC766_04190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IC766_04195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC766_04210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_04215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC766_04230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC766_04250	COG3811	Belongs to the UPF0386 family
IC766_04305	COG1309	transcriptional regulator
IC766_04310	COG1902	pentaerythritol trinitrate reductase activity
IC766_04315	COG0596	Alpha beta hydrolase
IC766_04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC766_04320	COG0596	Alpha beta hydrolase
IC766_04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC766_04325	COG0596	Alpha beta hydrolase
IC766_04330	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_04335	COG0583	DNA-binding transcription factor activity
IC766_04340	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IC766_04345	COG1012	belongs to the aldehyde dehydrogenase family
IC766_04365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_04370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC766_04375	COG0778	Nitroreductase
IC766_04390	COG1929	Belongs to the glycerate kinase type-1 family
IC766_04400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IC766_04405	COG3339	Conserved Protein
IC766_04430	COG1115	amino acid carrier protein
IC766_04435	COG1113	amino acid transport
IC766_04445	COG0019	diaminopimelate decarboxylase activity
IC766_04460	COG1280	lysine exporter protein (LysE YggA)
IC766_04465	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC766_04485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC766_04495	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC766_04505	COG0463	Glycosyl transferase, family 2
IC766_04525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_04560	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC766_04565	COG1136	(ABC) transporter
IC766_04580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC766_04580	COG0616	signal peptide processing
IC766_04585	COG0596	Alpha beta hydrolase
IC766_04590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IC766_04600	COG0628	permease
IC766_04635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC766_04655	COG0823	Involved in the tonB-independent uptake of proteins
IC766_04675	COG0824	Thioesterase
IC766_04680	COG1473	amidohydrolase
IC766_04705	COG0047	phosphoribosylformylglycinamidine synthase activity
IC766_04705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IC766_04710	COG2814	Major facilitator Superfamily
IC766_04725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC766_04730	COG1024	Enoyl-CoA hydratase
IC766_04735	COG1056	cytidyltransferase-related domain
IC766_04735	COG1051	belongs to the nudix hydrolase family
IC766_04750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC766_04765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC766_04770	COG0602	queuosine metabolic process
IC766_04780	COG4625	pathogenesis
IC766_04785	COG0583	DNA-binding transcription factor activity
IC766_04790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IC766_04795	COG4208	sulfate ABC transporter
IC766_04800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IC766_04810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IC766_04815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC766_04820	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IC766_04840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC766_04850	COG0481	GTPase activity
IC766_04855	COG0681	Belongs to the peptidase S26 family
IC766_04870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC766_04880	COG1381	Involved in DNA repair and RecF pathway recombination
IC766_04885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC766_04895	COG4221	oxidoreductase activity
IC766_04940	COG3706	GGDEF domain
IC766_04945	COG0556	nucleotide-excision repair
IC766_05000	COG2070	2-Nitropropane dioxygenase
IC766_05015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC766_05030	COG1215	transferase activity, transferring glycosyl groups
IC766_05045	COG0415	Belongs to the DNA photolyase family
IC766_05055	COG1252	NADH dehydrogenase
IC766_05075	COG1187	pseudouridine synthase activity
IC766_05100	COG0477	Major facilitator Superfamily
IC766_05105	COG0583	DNA-binding transcription factor activity
IC766_05110	COG1823	symporter activity
IC766_05120	COG0612	Peptidase, M16
IC766_05145	COG0352	thiamine-phosphate diphosphorylase activity
IC766_05180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC766_05205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC766_05210	COG0076	glutamate decarboxylase activity
IC766_05220	COG1522	sequence-specific DNA binding
IC766_05225	COG3961	Belongs to the TPP enzyme family
IC766_05230	COG1113	amino acid transport
IC766_05235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC766_05240	COG0573	inorganic phosphate transmembrane transporter activity
IC766_05250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC766_05255	COG0616	signal peptide processing
IC766_05270	COG3647	Membrane
IC766_05295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC766_05300	COG1686	Belongs to the peptidase S11 family
IC766_05325	COG0583	DNA-binding transcription factor activity
IC766_05330	COG1067	ATP-dependent peptidase activity
IC766_05355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IC766_05370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC766_05375	COG1966	Carbon starvation protein
IC766_05380	COG2879	small protein
IC766_05390	COG0582	viral genome integration into host DNA
IC766_05420	COG2026	Addiction module toxin, RelE StbE family
IC766_05435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC766_05470	COG2814	Major facilitator Superfamily
IC766_05510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC766_05515	COG2423	ornithine cyclodeaminase activity
IC766_05525	COG2964	Protein conserved in bacteria
IC766_05530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IC766_05540	COG1741	Belongs to the pirin family
IC766_05555	COG3739	integral membrane protein
IC766_05575	COG0302	gtp cyclohydrolase
IC766_05585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IC766_05595	COG2840	Smr protein MutS2
IC766_05610	COG0512	Glutamine amidotransferase of anthranilate synthase
IC766_05625	COG0174	glutamine synthetase
IC766_05635	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC766_05670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IC766_05675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC766_05680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IC766_05700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IC766_05705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IC766_05710	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IC766_05725	COG1960	acyl-CoA dehydrogenase activity
IC766_05730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC766_05735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC766_05745	COG2223	nitrite transmembrane transporter activity
IC766_05755	COG0024	Methionine aminopeptidase
IC766_05760	COG0052	Belongs to the universal ribosomal protein uS2 family
IC766_05775	COG2207	Transcriptional regulator
IC766_05800	COG2951	lytic endotransglycosylase activity
IC766_05805	COG0772	Belongs to the SEDS family
IC766_05820	COG0842	Transport permease protein
IC766_05825	COG1131	(ABC) transporter
IC766_05865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_05880	COG4215	(ABC) transporter
IC766_05885	COG4160	amino acid transport
IC766_05890	COG4598	ABC transporter
IC766_05900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC766_05905	COG0826	peptidase U32
IC766_05910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC766_05915	COG0384	phenazine biosynthesis protein PhzF
IC766_05925	COG1720	tRNA m6t6A37 methyltransferase activity
IC766_05950	COG0642	Histidine kinase
IC766_05960	COG0494	nUDIX hydrolase
IC766_05970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IC766_05975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC766_05980	COG3139	Protein of unknown function (DUF1315)
IC766_05990	COG1301	dicarboxylic acid transport
IC766_05995	COG1960	acyl-CoA dehydrogenase activity
IC766_06015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IC766_06025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC766_06030	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC766_06050	COG1690	Belongs to the RtcB family
IC766_06055	COG1234	tRNA 3'-trailer cleavage
IC766_06060	COG4650	regulator
IC766_06085	COG2363	Small membrane protein
IC766_06105	COG0513	Belongs to the DEAD box helicase family
IC766_06115	COG0778	Nitroreductase
IC766_06175	COG1610	YqeY-like protein
IC766_06205	COG0515	serine threonine protein kinase
IC766_06205	COG2815	serine threonine protein kinase
IC766_06310	COG1335	isochorismatase
IC766_06315	COG0583	DNA-binding transcription factor activity
IC766_06335	COG0596	Alpha beta hydrolase
IC766_06345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IC766_06355	COG0786	glutamate:sodium symporter activity
IC766_06360	COG0475	glutathione-regulated potassium exporter activity
IC766_06360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC766_06365	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_06440	COG1309	transcriptional regulator
IC766_06450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC766_06450	COG2169	Transcriptional regulator
IC766_06465	COG2985	domain, Protein
IC766_06490	COG2995	paraquat-inducible protein a
IC766_06495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IC766_06495	COG3008	intermembrane lipid transfer
IC766_06505	COG2351	hydroxyisourate hydrolase activity
IC766_06520	COG5002	protein histidine kinase activity
IC766_06545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC766_06555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IC766_06560	COG0642	Histidine kinase
IC766_06565	COG0745	RESPONSE REGULATOR receiver
IC766_06590	COG2175	clavaminate synthase activity
IC766_06595	COG3246	L-lysine catabolic process to acetate
IC766_06600	COG2814	Major facilitator Superfamily
IC766_06615	COG2855	membrane
IC766_06660	COG1301	dicarboxylic acid transport
IC766_06675	COG2011	ABC-type metal ion transport system permease component
IC766_06680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC766_06685	COG1464	Belongs to the NlpA lipoprotein family
IC766_06690	COG0151	Belongs to the GarS family
IC766_06695	COG0138	bifunctional purine biosynthesis protein purh
IC766_06700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC766_06730	COG2308	Evidence 4 Homologs of previously reported genes of
IC766_06740	COG1305	Transglutaminase-like
IC766_06750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC766_06755	COG0305	Participates in initiation and elongation during chromosome replication
IC766_06780	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC766_06790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IC766_06820	COG0726	polysaccharide deacetylase
IC766_06820	COG1649	PFAM Uncharacterised BCR, COG1649
IC766_06825	COG1215	transferase activity, transferring glycosyl groups
IC766_06830	COG3658	cytochrome
IC766_06840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_06860	COG2890	protein-(glutamine-N5) methyltransferase activity
IC766_06865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC766_06870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC766_06885	COG1960	acyl-CoA dehydrogenase activity
IC766_06890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC766_06895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC766_06920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IC766_06925	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IC766_06930	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IC766_06935	COG2205	protein histidine kinase activity
IC766_06940	COG0745	RESPONSE REGULATOR receiver
IC766_06945	COG0174	glutamine synthetase
IC766_06965	COG0729	surface antigen
IC766_06995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC766_07000	COG2814	Major facilitator Superfamily
IC766_07010	COG0583	DNA-binding transcription factor activity
IC766_07025	COG1187	pseudouridine synthase activity
IC766_07045	COG0802	atpase or kinase
IC766_07050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IC766_07060	COG1923	regulation of RNA biosynthetic process
IC766_07065	COG0697	spore germination
IC766_07090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC766_07095	COG0519	Catalyzes the synthesis of GMP from XMP
IC766_07095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC766_07100	COG4302	ethanolamine ammonia-lyase activity
IC766_07105	COG4303	Ethanolamine ammonia lyase large subunit
IC766_07110	COG0531	amino acid
IC766_07130	COG1454	alcohol dehydrogenase
IC766_07135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC766_07145	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IC766_07165	COG0308	aminopeptidase N
IC766_07195	COG0625	glutathione transferase activity
IC766_07210	COG1605	Chorismate mutase
IC766_07255	COG4264	IucA IucC family
IC766_07265	COG4264	IucA IucC family
IC766_07270	COG2423	ornithine cyclodeaminase activity
IC766_07275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC766_07285	COG0668	transmembrane transport
IC766_07330	COG0488	(ABC) transporter
IC766_07335	COG0589	response to stress
IC766_07365	COG3135	benzoate transporter
IC766_07370	COG1522	sequence-specific DNA binding
IC766_07380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IC766_07385	COG0583	DNA-binding transcription factor activity
IC766_07395	COG0183	Belongs to the thiolase family
IC766_07400	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_07405	COG2030	dehydratase
IC766_07410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC766_07435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IC766_07450	COG0824	Thioesterase
IC766_07455	COG1454	alcohol dehydrogenase
IC766_07465	COG1335	isochorismatase
IC766_07480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC766_07510	COG0069	glutamate synthase activity
IC766_07535	COG3328	transposase activity
IC766_07565	COG2814	Major facilitator Superfamily
IC766_07580	COG0511	ligase activity, forming carbon-carbon bonds
IC766_07600	COG1116	anion transmembrane transporter activity
IC766_07600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC766_07605	COG0745	RESPONSE REGULATOR receiver
IC766_07615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC766_07615	COG2146	nitrite reductase [NAD(P)H] activity
IC766_07620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC766_07625	COG0243	molybdopterin cofactor binding
IC766_07635	COG0243	molybdopterin cofactor binding
IC766_07640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC766_07655	COG0315	cyclic pyranopterin monophosphate synthase activity
IC766_07655	COG0521	Mo-molybdopterin cofactor biosynthetic process
IC766_07660	COG0303	'Molybdopterin
IC766_07670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC766_07675	COG0697	spore germination
IC766_07695	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC766_07700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IC766_07755	COG2204	response regulator
IC766_07760	COG3852	Histidine kinase
IC766_07785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC766_07790	COG0575	Belongs to the CDS family
IC766_07805	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC766_07825	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC766_07840	COG2137	regulation of response to DNA damage stimulus
IC766_07850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC766_07855	COG1011	Hydrolase
IC766_07870	COG3328	transposase activity
IC766_07890	COG0659	secondary active sulfate transmembrane transporter activity
IC766_07905	COG3300	MHYT domain
IC766_07905	COG5001	Diguanylate cyclase
IC766_07925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC766_07925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC766_07925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC766_07930	COG1105	Belongs to the carbohydrate kinase PfkB family
IC766_07935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC766_07935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC766_07965	COG0024	Methionine aminopeptidase
IC766_07970	COG0583	DNA-binding transcription factor activity
IC766_07980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IC766_07985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC766_07990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IC766_08015	COG0552	protein localization to endoplasmic reticulum
IC766_08040	COG4890	Cyd operon protein YbgT
IC766_08045	COG1294	oxidase, subunit
IC766_08060	COG1585	Membrane protein implicated in regulation of membrane protease activity
IC766_08070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC766_08075	COG4774	siderophore transport
IC766_08090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC766_08095	COG0569	domain protein
IC766_08100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IC766_08130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC766_08135	COG0542	response to heat
IC766_08160	COG1902	pentaerythritol trinitrate reductase activity
IC766_08160	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC766_08200	COG0148	phosphopyruvate hydratase activity
IC766_08205	COG2323	membrane
IC766_08215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC766_08225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC766_08230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC766_08235	COG0183	Belongs to the thiolase family
IC766_08240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC766_08245	COG0596	Alpha beta hydrolase
IC766_08250	COG2271	Major facilitator Superfamily
IC766_08255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IC766_08260	COG3485	protocatechuate 3,4-dioxygenase
IC766_08265	COG3485	protocatechuate 3,4-dioxygenase
IC766_08270	COG0710	3-dehydroquinate dehydratase activity
IC766_08275	COG3420	alginic acid biosynthetic process
IC766_08280	COG3659	wide pore channel activity
IC766_08285	COG4993	Dehydrogenase
IC766_08295	COG2391	methyltransferase activity
IC766_08310	COG1414	Transcriptional regulator
IC766_08315	COG0583	DNA-binding transcription factor activity
IC766_08320	COG1960	acyl-CoA dehydrogenase activity
IC766_08345	COG2814	Major facilitator Superfamily
IC766_08355	COG0154	amidase activity
IC766_08375	COG4638	Rieske (2fe-2S)
IC766_08385	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_08395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC766_08405	COG3733	amine oxidase
IC766_08420	COG1012	belongs to the aldehyde dehydrogenase family
IC766_08425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC766_08430	COG0183	Belongs to the thiolase family
IC766_08435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC766_08440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC766_08450	COG4829	muconolactone delta-isomerase
IC766_08455	COG4948	Mandelate Racemase Muconate Lactonizing
IC766_08460	COG0583	DNA-binding transcription factor activity
IC766_08490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC766_08515	COG1309	transcriptional regulator
IC766_08600	COG2188	Transcriptional regulator
IC766_08615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC766_08630	COG2271	Major facilitator Superfamily
IC766_08640	COG1566	PFAM secretion protein HlyD family protein
IC766_08670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC766_08675	COG1120	ATPase activity
IC766_08695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC766_08815	COG2175	clavaminate synthase activity
IC766_08820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC766_08835	COG0667	Aldo Keto reductase
IC766_08840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_08855	COG2175	clavaminate synthase activity
IC766_08885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC766_08890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_08895	COG4771	TonB-dependent receptor
IC766_08925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_08930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC766_08935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC766_08940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC766_08955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC766_08960	COG0805	protein transport
IC766_08970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_08990	COG1132	(ABC) transporter
IC766_08995	COG1132	(ABC) transporter
IC766_09015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC766_09020	COG0601	transmembrane transport
IC766_09050	COG3539	Fimbrial protein
IC766_09075	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC766_09085	COG0753	catalase activity
IC766_09095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC766_09100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC766_09110	COG2205	protein histidine kinase activity
IC766_09115	COG0745	RESPONSE REGULATOR receiver
IC766_09120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_09125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC766_09185	COG4771	TonB-dependent receptor
IC766_09190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC766_09195	COG1535	isochorismatase
IC766_09195	COG3433	isochorismatase activity
IC766_09200	COG1021	2,3-dihydroxybenzoate-AMP ligase
IC766_09205	COG1169	isochorismate synthase
IC766_09210	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_09220	COG3251	PFAM MbtH domain protein
IC766_09225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IC766_09250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC766_09255	COG4149	molybdate abc transporter
IC766_09260	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC766_09270	COG4638	Rieske (2fe-2S)
IC766_09275	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC766_09280	COG0543	2 iron, 2 sulfur cluster binding
IC766_09280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC766_09295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC766_09305	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_09325	COG2207	Transcriptional regulator
IC766_09330	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_09335	COG2610	gluconate transmembrane transporter activity
IC766_09340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC766_09370	COG2814	Major facilitator Superfamily
IC766_09395	COG0583	DNA-binding transcription factor activity
IC766_09410	COG2031	fatty acid transporter
IC766_09415	COG0183	Belongs to the thiolase family
IC766_09420	COG0583	DNA-binding transcription factor activity
IC766_09425	COG0583	DNA-binding transcription factor activity
IC766_09440	COG1027	Aspartate ammonia-lyase
IC766_09450	COG0477	Major facilitator Superfamily
IC766_09460	COG3708	Transcriptional regulator
IC766_09460	COG2207	Transcriptional regulator
IC766_09475	COG0730	response to heat
IC766_09485	COG3453	Protein conserved in bacteria
IC766_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC766_09495	COG3781	membrane
IC766_09500	COG1063	alcohol dehydrogenase
IC766_09510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC766_09515	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC766_09520	COG0022	dehydrogenase e1 component
IC766_09525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IC766_09530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IC766_09545	COG3706	GGDEF domain
IC766_09560	COG0133	tryptophan synthase activity
IC766_09570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IC766_09605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC766_09630	COG2226	methyltransferase
IC766_09680	COG0842	Transport permease protein
IC766_09685	COG0842	Transport permease protein
IC766_09690	COG3328	transposase activity
IC766_09700	COG3328	transposase activity
IC766_09720	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC766_09725	COG4773	Receptor
IC766_09745	COG0730	response to heat
IC766_09750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC766_09765	COG0406	alpha-ribazole phosphatase activity
IC766_09770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC766_09785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC766_09790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC766_09805	COG1960	acyl-CoA dehydrogenase activity
IC766_09810	COG1960	acyl-CoA dehydrogenase activity
IC766_09815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC766_09820	COG2207	Transcriptional regulator
IC766_09825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC766_09830	COG0776	regulation of translation
IC766_09855	COG0822	iron-sulfur transferase activity
IC766_09860	COG0316	Belongs to the HesB IscA family
IC766_09890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IC766_09910	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IC766_09915	COG0702	epimerase
IC766_09945	COG4172	Belongs to the ABC transporter superfamily
IC766_09950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC766_09955	COG0601	transmembrane transport
IC766_09980	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC766_10005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IC766_10010	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC766_10025	COG2431	L-lysine efflux transmembrane transporter activity
IC766_10040	COG0776	regulation of translation
IC766_10105	COG0084	hydrolase, TatD family'
IC766_10125	COG1663	tetraacyldisaccharide 4'-kinase activity
IC766_10130	COG1132	(ABC) transporter
IC766_10140	COG0811	peptide transport
IC766_10145	COG1475	DNA binding
IC766_10150	COG1192	Involved in chromosome partitioning
IC766_10160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC766_10200	COG0424	maF-like protein
IC766_10205	COG2850	peptidyl-arginine hydroxylation
IC766_10225	COG3619	membrane
IC766_10230	COG3122	Protein conserved in bacteria
IC766_10235	COG1132	(ABC) transporter
IC766_10255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC766_10260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC766_10270	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC766_10270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IC766_10270	COG0506	proline dehydrogenase activity
IC766_10275	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC766_10290	COG3698	Phosphodiester glycosidase
IC766_10300	COG2353	YceI-like domain
IC766_10315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IC766_10355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IC766_10355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IC766_10380	COG3539	Fimbrial protein
IC766_10385	COG3121	Chaperone
IC766_10405	COG0697	spore germination
IC766_10415	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC766_10425	COG0583	DNA-binding transcription factor activity
IC766_10445	COG2197	response regulator
IC766_10470	COG1522	sequence-specific DNA binding
IC766_10480	COG1126	abc transporter atp-binding protein
IC766_10485	COG0765	amino acid transport
IC766_10490	COG0765	amino acid transport
IC766_10520	COG1464	Belongs to the NlpA lipoprotein family
IC766_10530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IC766_10535	COG2011	ABC-type metal ion transport system permease component
IC766_10540	COG0012	GTP binding
IC766_10565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IC766_10600	COG2207	Transcriptional regulator
IC766_10600	COG1917	Cupin 2, conserved barrel domain protein
IC766_10605	COG0386	Belongs to the glutathione peroxidase family
IC766_10615	COG0436	Aminotransferase
IC766_10620	COG1301	dicarboxylic acid transport
IC766_10655	COG3634	alkyl hydroperoxide reductase activity
IC766_10670	COG0583	DNA-binding transcription factor activity
IC766_10675	COG0431	NADPH-dependent FMN reductase
IC766_10680	COG0798	PFAM Bile acid sodium symporter
IC766_10685	COG0640	Transcriptional regulator
IC766_10700	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IC766_10710	COG0583	DNA-binding transcription factor activity
IC766_10720	COG1953	Uracil, thiamine, allantoin
IC766_10730	COG2175	clavaminate synthase activity
IC766_10735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC766_10740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IC766_10745	COG4521	taurine ABC transporter
IC766_10755	COG0477	Major facilitator Superfamily
IC766_10775	COG1271	oxidase subunit
IC766_10780	COG1294	oxidase, subunit
IC766_10790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC766_10810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IC766_10830	COG3052	prosthetic group binding
IC766_10835	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IC766_10860	COG1346	cytolysis
IC766_10870	COG0583	DNA-binding transcription factor activity
IC766_10875	COG0625	glutathione transferase activity
IC766_10880	COG0625	glutathione transferase activity
IC766_10885	COG0583	DNA-binding transcription factor activity
IC766_10900	COG1045	serine acetyltransferase
IC766_10905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC766_10910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC766_10915	COG1280	lysine exporter protein (LysE YggA)
IC766_10925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC766_10930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC766_10940	COG0765	amino acid transport
IC766_10945	COG0765	amino acid transport
IC766_10985	COG0784	Response regulator, receiver
IC766_10985	COG2205	protein histidine kinase activity
IC766_11005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC766_11025	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_11070	COG0583	DNA-binding transcription factor activity
IC766_11090	COG0318	PFAM AMP-dependent synthetase and ligase
IC766_11095	COG1309	transcriptional regulator
IC766_11100	COG1960	acyl-CoA dehydrogenase activity
IC766_11105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC766_11110	COG1024	Enoyl-CoA hydratase
IC766_11115	COG4770	biotin carboxylase activity
IC766_11125	COG0583	DNA-binding transcription factor activity
IC766_11140	COG1960	acyl-CoA dehydrogenase activity
IC766_11150	COG2814	Major facilitator Superfamily
IC766_11160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IC766_11165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IC766_11170	COG2814	Major facilitator Superfamily
IC766_11175	COG1960	acyl-CoA dehydrogenase activity
IC766_11180	COG1024	Enoyl-CoA hydratase
IC766_11185	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_11190	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC766_11195	COG0183	Belongs to the thiolase family
IC766_11205	COG2814	Major facilitator Superfamily
IC766_11220	COG1024	Enoyl-CoA hydratase
IC766_11230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC766_11235	COG1960	acyl-CoA dehydrogenase activity
IC766_11240	COG2814	Major facilitator Superfamily
IC766_11245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC766_11250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC766_11265	COG3842	ATPase activity
IC766_11270	COG1840	ABC-type Fe3 transport system, periplasmic component
IC766_11285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC766_11290	COG1414	Transcriptional regulator
IC766_11300	COG0583	DNA-binding transcription factor activity
IC766_11315	COG3038	cytochrome b561
IC766_11320	COG0753	catalase activity
IC766_11325	COG0531	amino acid
IC766_11330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC766_11345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IC766_11350	COG1309	transcriptional regulator
IC766_11385	COG3179	chitinase
IC766_11405	COG0406	alpha-ribazole phosphatase activity
IC766_11415	COG2050	protein possibly involved in aromatic compounds catabolism
IC766_11425	COG3327	negative regulation of DNA-templated transcription, initiation
IC766_11430	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IC766_11440	COG1250	3-hydroxyacyl-CoA dehydrogenase
IC766_11445	COG1024	Enoyl-CoA hydratase
IC766_11450	COG1024	Enoyl-CoA hydratase
IC766_11455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC766_11460	COG2151	metal-sulfur cluster biosynthetic enzyme
IC766_11465	COG3396	Phenylacetate-CoA oxygenase
IC766_11470	COG3460	Phenylacetate-CoA oxygenase
IC766_11475	COG3396	Phenylacetate-CoA oxygenase
IC766_11480	COG2030	dehydratase
IC766_11480	COG1012	belongs to the aldehyde dehydrogenase family
IC766_11485	COG1760	l-serine dehydratase
IC766_11495	COG0789	Transcriptional regulator
IC766_11505	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC766_11510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC766_11525	COG2807	transmembrane transport
IC766_11530	COG0590	tRNA wobble adenosine to inosine editing
IC766_11635	COG0477	Major facilitator Superfamily
IC766_11650	COG1116	anion transmembrane transporter activity
IC766_11655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC766_11665	COG0864	Transcriptional regulator
IC766_11680	COG1733	regulation of RNA biosynthetic process
IC766_11685	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC766_11690	COG0439	Biotin carboxylase
IC766_11705	COG1063	alcohol dehydrogenase
IC766_11750	COG0038	chloride channel
IC766_11755	COG4770	biotin carboxylase activity
IC766_11775	COG1914	H( )-stimulated, divalent metal cation uptake system
IC766_11780	COG0583	DNA-binding transcription factor activity
IC766_11790	COG1595	DNA-templated transcription, initiation
IC766_11800	COG3220	belongs to the UPF0276 family
IC766_11815	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_11830	COG2076	Multidrug Resistance protein
IC766_11845	COG3713	MltA-interacting MipA family protein
IC766_11850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC766_11895	COG3209	COG3209 Rhs family protein
IC766_11985	COG1309	transcriptional regulator
IC766_11990	COG1278	Cold shock
IC766_12005	COG1522	sequence-specific DNA binding
IC766_12015	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_12025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC766_12030	COG4774	siderophore transport
IC766_12050	COG2814	Major facilitator Superfamily
IC766_12065	COG0402	S-adenosylhomocysteine deaminase activity
IC766_12070	COG0583	DNA-binding transcription factor activity
IC766_12080	COG1271	oxidase subunit
IC766_12085	COG1294	oxidase, subunit
IC766_12090	COG1469	GTP cyclohydrolase I activity
IC766_12110	COG1560	Kdo2-lipid A biosynthetic process
IC766_12155	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC766_12165	COG4122	O-methyltransferase activity
IC766_12195	COG1538	Outer membrane efflux protein
IC766_12200	COG3328	transposase activity
IC766_12210	COG1137	ATPase activity
IC766_12215	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IC766_12225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IC766_12230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC766_12230	COG0517	IMP dehydrogenase activity
IC766_12250	COG0667	Aldo Keto reductase
IC766_12260	COG2814	Major facilitator Superfamily
IC766_12290	COG1278	Cold shock
IC766_12295	COG1280	lysine exporter protein (LysE YggA)
IC766_12330	COG1570	exodeoxyribonuclease VII activity
IC766_12415	COG2871	sodium ion transport
IC766_12425	COG0583	DNA-binding transcription factor activity
IC766_12435	COG4638	Rieske (2fe-2S)
IC766_12440	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IC766_12445	COG0543	2 iron, 2 sulfur cluster binding
IC766_12445	COG0633	Ferredoxin
IC766_12450	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_12455	COG3135	benzoate transporter
IC766_12460	COG2814	Major facilitator Superfamily
IC766_12475	COG1643	Atp-dependent helicase
IC766_12490	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IC766_12510	COG3634	alkyl hydroperoxide reductase activity
IC766_12530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC766_12535	COG0625	glutathione transferase activity
IC766_12580	COG0542	response to heat
IC766_12595	COG1765	OsmC-like protein
IC766_12605	COG0667	Aldo Keto reductase
IC766_12620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC766_12635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC766_12645	COG0527	aspartate kinase activity
IC766_12655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC766_12665	COG3038	cytochrome b561
IC766_12670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IC766_12675	COG2252	PERMEase
IC766_12685	COG2072	flavoprotein involved in K transport
IC766_12700	COG1741	Belongs to the pirin family
IC766_12705	COG1309	transcriptional regulator
IC766_12720	COG2072	flavoprotein involved in K transport
IC766_12725	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC766_12730	COG0583	DNA-binding transcription factor activity
IC766_12745	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC766_12775	COG1944	ATP diphosphatase activity
IC766_12795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC766_12810	COG2814	Major facilitator Superfamily
IC766_12815	COG1024	Enoyl-CoA hydratase
IC766_12820	COG1012	belongs to the aldehyde dehydrogenase family
IC766_12830	COG1960	acyl-CoA dehydrogenase activity
IC766_12850	COG0697	spore germination
IC766_12870	COG1113	amino acid transport
IC766_12890	COG1012	belongs to the aldehyde dehydrogenase family
IC766_12910	COG0531	amino acid
IC766_12920	COG1113	amino acid transport
IC766_12955	COG3209	COG3209 Rhs family protein
IC766_12970	COG1846	Transcriptional regulator
IC766_13020	COG4269	membrane
IC766_13040	COG0583	DNA-binding transcription factor activity
IC766_13050	COG0251	oxidation-reduction process
IC766_13065	COG0446	pyridine nucleotide-disulphide oxidoreductase
IC766_13065	COG1902	pentaerythritol trinitrate reductase activity
IC766_13075	COG4251	negative regulation of phosphorylation
IC766_13075	COG2203	Gaf domain
IC766_13075	COG5001	Diguanylate cyclase
IC766_13075	COG3706	GGDEF domain
IC766_13085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC766_13110	COG4172	Belongs to the ABC transporter superfamily
IC766_13115	COG4239	(ABC) transporter, permease
IC766_13120	COG4174	ABC transporter (Permease)
IC766_13130	COG0741	lytic transglycosylase activity
IC766_13130	COG1388	LysM domain
IC766_13175	COG0583	DNA-binding transcription factor activity
IC766_13200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC766_13205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC766_13210	COG0006	proline dipeptidase activity
IC766_13245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IC766_13280	COG3384	dioxygenase
IC766_13290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IC766_13295	COG2878	Part of a membrane complex involved in electron transport
IC766_13300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IC766_13325	COG0768	penicillin binding
IC766_13330	COG0742	ribosomal rna small subunit methyltransferase
IC766_13350	COG0830	nickel cation binding
IC766_13360	COG0804	urea catabolic process
IC766_13400	COG1253	flavin adenine dinucleotide binding
IC766_13405	COG2851	Citrate transporter
IC766_13455	COG1773	rubredoxin
IC766_13460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC766_13470	COG0583	DNA-binding transcription factor activity
IC766_13495	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IC766_13500	COG4181	ATPase activity
IC766_13545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IC766_13565	COG0306	phosphate transporter
IC766_13600	COG2223	nitrite transmembrane transporter activity
IC766_13605	COG2207	Transcriptional regulator
IC766_13610	COG2066	Belongs to the glutaminase family
IC766_13615	COG0242	peptide deformylase activity
IC766_13620	COG0477	Major facilitator Superfamily
IC766_13630	COG0028	Belongs to the TPP enzyme family
IC766_13645	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_13650	COG2267	carboxylic ester hydrolase activity
IC766_13660	COG2271	Major facilitator Superfamily
IC766_13695	COG1414	Transcriptional regulator
IC766_13725	COG1024	Enoyl-CoA hydratase
IC766_13735	COG1215	transferase activity, transferring glycosyl groups
IC766_13740	COG0726	polysaccharide deacetylase
IC766_13740	COG1649	PFAM Uncharacterised BCR, COG1649
IC766_13750	COG4681	YaeQ
IC766_13760	COG0523	cobalamin synthesis protein
IC766_13770	COG1607	acyl-coa hydrolase
IC766_13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC766_13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IC766_13790	COG1309	transcriptional regulator
IC766_13815	COG2040	homocysteine
IC766_13820	COG0531	amino acid
IC766_13840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC766_13845	COG0477	Major facilitator Superfamily
IC766_13875	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IC766_13880	COG3586	endonuclease activity
IC766_13940	COG0405	Gamma-glutamyltransferase
IC766_13945	COG2814	Major facilitator Superfamily
IC766_13955	COG2050	protein possibly involved in aromatic compounds catabolism
IC766_13970	COG1090	epimerase
IC766_13990	COG0420	3'-5' exonuclease activity
IC766_14000	COG1968	undecaprenyl-diphosphatase activity
IC766_14020	COG0735	belongs to the Fur family
IC766_14025	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC766_14030	COG2914	Belongs to the UPF0125 (RnfH) family
IC766_14045	COG0121	glutamine amidotransferase
IC766_14060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC766_14070	COG0210	DNA helicase
IC766_14075	COG2885	chlorophyll binding
IC766_14080	COG0204	Acyl-transferase
IC766_14095	COG2894	cell division
IC766_14110	COG1280	lysine exporter protein (LysE YggA)
IC766_14115	COG1674	ftsk spoiiie
IC766_14120	COG0492	ferredoxin-NADP+ reductase activity
IC766_14125	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC766_14135	COG0456	acetyltransferase
IC766_14155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IC766_14165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IC766_14180	COG1981	membrane
IC766_14190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC766_14190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IC766_14210	COG1012	belongs to the aldehyde dehydrogenase family
IC766_14215	COG4638	Rieske (2fe-2S)
IC766_14220	COG0657	acetylesterase activity
IC766_14230	COG0473	3-isopropylmalate dehydrogenase activity
IC766_14235	COG0583	DNA-binding transcription factor activity
IC766_14255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC766_14265	COG0582	viral genome integration into host DNA
IC766_14450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC766_14525	COG0564	pseudouridine synthase activity
IC766_14535	COG0358	DNA primase activity
IC766_14550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC766_14580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC766_14610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC766_14620	COG0352	thiamine-phosphate diphosphorylase activity
IC766_14620	COG0351	phosphomethylpyrimidine kinase
IC766_14620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC766_14625	COG1652	LysM domain
IC766_14650	COG1399	metal-binding, possibly nucleic acid-binding protein
IC766_14655	COG3101	peptidyl-lysine hydroxylation
IC766_14660	COG0009	L-threonylcarbamoyladenylate synthase
IC766_14665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IC766_14670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IC766_14685	COG4106	trans-aconitate 2-methyltransferase activity
IC766_14700	COG0596	Alpha beta hydrolase
IC766_14700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC766_14700	COG2226	methyltransferase
IC766_14705	COG1877	trehalose-phosphatase activity
IC766_14710	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IC766_14715	COG2223	nitrite transmembrane transporter activity
IC766_14735	COG1196	nuclear chromosome segregation
IC766_14745	COG0730	response to heat
IC766_14760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IC766_14770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC766_14815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC766_14820	COG0489	protein tyrosine kinase activity
IC766_14830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC766_14830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC766_14865	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IC766_14870	COG2081	HI0933 family
IC766_14880	COG0668	transmembrane transport
IC766_14900	COG0583	DNA-binding transcription factor activity
IC766_14925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC766_14930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC766_14945	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IC766_14960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IC766_14985	COG3706	GGDEF domain
IC766_15000	COG0745	RESPONSE REGULATOR receiver
IC766_15020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC766_15050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IC766_15055	COG0583	DNA-binding transcription factor activity
IC766_15075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IC766_15090	COG0583	DNA-binding transcription factor activity
IC766_15100	COG0583	DNA-binding transcription factor activity
IC766_15115	COG0583	DNA-binding transcription factor activity
IC766_15120	COG1053	succinate dehydrogenase
IC766_15135	COG1309	transcriptional regulator
IC766_15145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IC766_15150	COG2814	Major facilitator Superfamily
IC766_15155	COG1960	acyl-CoA dehydrogenase activity
IC766_15160	COG0583	DNA-binding transcription factor activity
IC766_15195	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IC766_15200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC766_15220	COG2132	Multicopper oxidase
IC766_15230	COG0561	phosphatase activity
IC766_15235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC766_15245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC766_15260	COG1214	PFAM Peptidase M22, glycoprotease
IC766_15310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC766_15320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC766_15325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IC766_15330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IC766_15390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC766_15400	COG1846	Transcriptional regulator
IC766_15405	COG1764	response to oxidative stress
IC766_15445	COG0037	tRNA processing
IC766_15455	COG0248	Ppx GppA phosphatase
IC766_15485	COG0072	phenylalanine-tRNA ligase activity
IC766_15515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC766_15525	COG1238	metal cluster binding
IC766_15530	COG0625	glutathione transferase activity
IC766_15545	COG0318	PFAM AMP-dependent synthetase and ligase
IC766_15550	COG3028	Belongs to the UPF0307 family
IC766_15575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC766_15580	COG0617	tRNA 3'-terminal CCA addition
IC766_15585	COG1555	photosystem II stabilization
IC766_15590	COG3956	TIGRFAM MazG family protein
IC766_15600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IC766_15620	COG0784	Response regulator, receiver
IC766_15620	COG5002	protein histidine kinase activity
IC766_15620	COG2205	protein histidine kinase activity
IC766_15625	COG1024	Enoyl-CoA hydratase
IC766_15630	COG2084	Dehydrogenase
IC766_15635	COG3622	Belongs to the hyi family
IC766_15670	COG0697	spore germination
IC766_15680	COG2814	Major facilitator Superfamily
IC766_15685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC766_15815	COG4695	Portal protein
IC766_15820	COG1802	Transcriptional regulator
IC766_15820	COG4626	Terminase
IC766_15870	COG3620	sequence-specific DNA binding
IC766_15930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC766_15940	COG0583	DNA-binding transcription factor activity
IC766_15950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC766_15960	COG0084	hydrolase, TatD family'
IC766_15975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IC766_16100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IC766_16105	COG0440	acetolactate synthase activity
IC766_16110	COG0028	Belongs to the TPP enzyme family
IC766_16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC766_16140	COG1136	(ABC) transporter
IC766_16140	COG0577	efflux transmembrane transporter activity
IC766_16145	COG1538	Outer membrane efflux protein
IC766_16160	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC766_16165	COG1162	GTPase activity
IC766_16175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC766_16215	COG1426	Protein conserved in bacteria
IC766_16250	COG0793	Belongs to the peptidase S41A family
IC766_16265	COG2267	carboxylic ester hydrolase activity
IC766_16275	COG1012	belongs to the aldehyde dehydrogenase family
IC766_16280	COG3265	gluconokinase activity
IC766_16290	COG0800	Aldolase
IC766_16300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC766_16305	COG0280	phosphate acetyltransferase
IC766_16305	COG0857	belongs to the CobB CobQ family
IC766_16310	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IC766_16310	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IC766_16330	COG0740	serine-type endopeptidase activity
IC766_16340	COG4774	siderophore transport
IC766_16350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IC766_16360	COG2813	Specifically methylates the guanine in position
IC766_16360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IC766_16455	COG0788	formyltetrahydrofolate deformylase activity
IC766_16480	COG4651	solute:proton antiporter activity
IC766_16480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC766_16500	COG0724	RNA recognition motif
IC766_16505	COG0210	DNA helicase
IC766_16530	COG1733	regulation of RNA biosynthetic process
IC766_16540	COG2900	Belongs to the SlyX family
IC766_16545	COG0488	(ABC) transporter
IC766_16555	COG1280	lysine exporter protein (LysE YggA)
IC766_16560	COG1560	Kdo2-lipid A biosynthetic process
IC766_16570	COG1301	dicarboxylic acid transport
IC766_16625	COG0473	3-isopropylmalate dehydrogenase activity
IC766_16650	COG0583	DNA-binding transcription factor activity
IC766_16695	COG0583	DNA-binding transcription factor activity
IC766_16705	COG0625	glutathione transferase activity
IC766_16710	COG2378	regulation of single-species biofilm formation
IC766_16725	COG1530	ribonuclease E activity
IC766_16730	COG0318	PFAM AMP-dependent synthetase and ligase
IC766_16745	COG0583	DNA-binding transcription factor activity
IC766_16750	COG4221	oxidoreductase activity
IC766_16755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC766_16765	COG0534	Mate efflux family protein
IC766_16780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC766_16810	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC766_16810	COG0493	'glutamate synthase
IC766_16820	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IC766_16825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC766_16840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC766_16850	COG0644	oxidoreductase
IC766_16850	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IC766_16865	COG4535	Mg2 and Co2 transporter CorC
IC766_16875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC766_16900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IC766_16905	COG0475	glutathione-regulated potassium exporter activity
IC766_16905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IC766_16910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC766_16920	COG0484	heat shock protein binding
IC766_16925	COG0789	Transcriptional regulator
IC766_16930	COG0598	Magnesium transport protein CorA
IC766_16935	COG1185	polyribonucleotide nucleotidyltransferase activity
IC766_16945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IC766_16950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC766_16955	COG1074	ATP-dependent DNA helicase activity
IC766_16960	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IC766_16985	COG2226	methyltransferase
IC766_17000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IC766_17015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IC766_17030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IC766_17030	COG2111	Na H antiporter
IC766_17035	COG1006	Multisubunit Na H antiporter MnhC subunit
IC766_17040	COG0651	ATP synthesis coupled electron transport
IC766_17045	COG1863	multisubunit Na H antiporter MnhE subunit
IC766_17050	COG2212	antiporter activity
IC766_17055	COG1320	monovalent cation:proton antiporter activity
IC766_17060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC766_17070	COG0195	Participates in both transcription termination and antitermination
IC766_17120	COG0237	dephospho-CoA kinase activity
IC766_17130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC766_17140	COG0497	DNA recombination
IC766_17150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC766_17165	COG1289	transmembrane transporter activity
IC766_17180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC766_17240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IC766_17255	COG0326	Molecular chaperone. Has ATPase activity
IC766_17270	COG2056	Na+-H+ antiporter family
IC766_17275	COG0596	Alpha beta hydrolase
IC766_17370	COG0546	phosphoglycolate phosphatase activity
IC766_17375	COG1716	ATPase activity
IC766_17420	COG0181	hydroxymethylbilane synthase activity
IC766_17430	COG3275	phosphorelay sensor kinase activity
IC766_17450	COG1538	Outer membrane efflux protein
IC766_17460	COG0697	spore germination
IC766_17480	COG0494	nUDIX hydrolase
IC766_17490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC766_17495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC766_17525	COG4974	Belongs to the 'phage' integrase family
IC766_17530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC766_17540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC766_17550	COG2197	response regulator
IC766_17565	COG0793	Belongs to the peptidase S41A family
IC766_17570	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IC766_17575	COG0795	lipopolysaccharide-transporting ATPase activity
IC766_17580	COG0795	lipopolysaccharide-transporting ATPase activity
IC766_17615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC766_17615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC766_17625	COG0004	ammonium transporteR
IC766_17630	COG0347	Belongs to the P(II) protein family
IC766_17640	COG0606	chelatase, subunit chli
IC766_17645	COG0431	NADPH-dependent FMN reductase
IC766_17650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC766_17655	COG0235	Class ii aldolase
IC766_17660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC766_17675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC766_17690	COG0318	PFAM AMP-dependent synthetase and ligase
IC766_17700	COG0477	Major facilitator Superfamily
IC766_17705	COG2860	membrane
IC766_17715	COG1253	flavin adenine dinucleotide binding
IC766_17725	COG2814	Major facilitator Superfamily
IC766_17735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IC766_17770	COG0655	NAD(P)H dehydrogenase (quinone) activity
IC766_17785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC766_17820	COG1309	transcriptional regulator
IC766_17855	COG0758	DNA mediated transformation
IC766_17865	COG0697	spore germination
IC766_17870	COG1309	transcriptional regulator
IC766_17885	COG0386	Belongs to the glutathione peroxidase family
IC766_17895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IC766_17900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IC766_17950	COG1121	(ABC) transporter
IC766_17955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC766_17960	COG1280	lysine exporter protein (LysE YggA)
IC766_17965	COG2837	iron assimilation
IC766_17975	COG0281	malic enzyme
IC766_18010	COG0735	belongs to the Fur family
IC766_18020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC766_18025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC766_18025	COG0519	Catalyzes the synthesis of GMP from XMP
IC766_18030	COG4399	Belongs to the UPF0754 family
IC766_18035	COG2259	Doxx family
IC766_18040	COG0586	Pfam SNARE associated Golgi protein
IC766_18055	COG1192	Involved in chromosome partitioning
IC766_18065	COG0271	Belongs to the BolA IbaG family
IC766_18105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC766_18105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC766_18105	COG3321	synthase
IC766_18105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IC766_18110	COG1960	acyl-CoA dehydrogenase activity
IC766_18120	COG2197	response regulator
IC766_18130	COG3916	Acyl-homoserine-lactone synthase
IC766_18135	COG0477	Major facilitator Superfamily
IC766_18140	COG1024	Enoyl-CoA hydratase
IC766_18145	COG1024	Enoyl-CoA hydratase
IC766_18150	COG1960	acyl-CoA dehydrogenase activity
IC766_18155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC766_18175	COG1113	amino acid transport
IC766_18180	COG1113	amino acid transport
IC766_18185	COG0251	oxidation-reduction process
IC766_18225	COG0564	pseudouridine synthase activity
IC766_18295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IC766_18310	COG1802	Transcriptional regulator
IC766_18320	COG1448	Aminotransferase
IC766_18325	COG0277	FAD linked oxidase domain protein
IC766_18335	COG2186	Transcriptional regulator
IC766_18345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC766_18365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IC766_18370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC766_18385	COG0110	maltose O-acetyltransferase activity
IC766_18390	COG0463	Glycosyl transferase, family 2
IC766_18390	COG1216	Glycosyl transferase, family 2
IC766_18425	COG1086	Polysaccharide biosynthesis protein
IC766_18435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IC766_18440	COG1091	dTDP-4-dehydrorhamnose reductase activity
IC766_18450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IC766_18455	COG1596	polysaccharide export
IC766_18480	COG0728	peptidoglycan biosynthetic process
IC766_18485	COG3023	N-Acetylmuramoyl-L-alanine amidase
IC766_18540	COG0546	phosphoglycolate phosphatase activity
IC766_18545	COG1028	Short-chain dehydrogenase reductase Sdr
IC766_18560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC766_18560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC766_18565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC766_18570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC766_18575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IC766_18580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC766_18585	COG1116	anion transmembrane transporter activity
IC766_18590	COG1309	transcriptional regulator
IC766_18595	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC766_18605	COG0196	riboflavin kinase activity
IC766_18610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC766_18620	COG1047	Peptidyl-prolyl cis-trans
IC766_18660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC766_18665	COG0657	acetylesterase activity
IC766_18680	COG3328	transposase activity
IC766_18720	COG2951	lytic endotransglycosylase activity
IC766_18725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC766_18740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC766_18750	COG0671	phosphoesterase, PA-phosphatase related
IC766_18755	COG0861	Integral membrane protein TerC family
IC766_18765	COG0754	glutathionylspermidine amidase activity
IC766_18775	COG0402	S-adenosylhomocysteine deaminase activity
IC766_18790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IC766_18840	COG2132	Multicopper oxidase
IC766_18905	COG0789	Transcriptional regulator
IC766_19070	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
IC766_19105	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IC766_19110	COG0659	secondary active sulfate transmembrane transporter activity
IC766_19125	COG3328	transposase activity
IC766_19130	COG0583	DNA-binding transcription factor activity
IC766_19135	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC766_19140	COG3321	synthase
IC766_19140	COG0604	alcohol dehydrogenase
IC766_19150	COG0697	spore germination
IC766_19185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IC766_19200	COG1979	alcohol dehydrogenase
IC766_19210	COG1902	pentaerythritol trinitrate reductase activity
IC766_19220	COG1309	transcriptional regulator
IC766_19225	COG2130	NADP-dependent
IC766_19240	COG0582	viral genome integration into host DNA
IC766_19285	COG0210	DNA helicase
IC766_19305	COG0210	DNA helicase
IC766_19395	COG2217	Heavy metal translocating P-type atpase