locus-tag	class	description
BEN76_00010	COG2969	positive regulation of protein catabolic process
BEN76_00015	COG0625	glutathione transferase activity
BEN76_00020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BEN76_00025	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BEN76_00035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BEN76_00040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BEN76_00055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BEN76_00065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEN76_00070	COG1408	metallophosphoesterase
BEN76_00080	COG0477	Major facilitator Superfamily
BEN76_00085	COG1272	protein, Hemolysin III
BEN76_00100	COG4667	esterase of the alpha-beta hydrolase superfamily
BEN76_00115	COG0183	Belongs to the thiolase family
BEN76_00120	COG2207	Transcriptional regulator
BEN76_00150	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN76_00170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BEN76_00175	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BEN76_00185	COG2205	protein histidine kinase activity
BEN76_00190	COG0745	RESPONSE REGULATOR receiver
BEN76_00205	COG3046	protein related to deoxyribodipyrimidine photolyase
BEN76_00225	COG2351	hydroxyisourate hydrolase activity
BEN76_00240	COG1113	amino acid transport
BEN76_00245	COG0142	geranyltranstransferase activity
BEN76_00260	COG1752	Esterase of the alpha-beta hydrolase superfamily
BEN76_00270	COG2814	Major facilitator Superfamily
BEN76_00275	COG0745	RESPONSE REGULATOR receiver
BEN76_00280	COG0642	Histidine kinase
BEN76_00290	COG0004	ammonium transporteR
BEN76_00325	COG0525	valine-tRNA ligase activity
BEN76_00335	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_00345	COG0393	Putative heavy-metal-binding
BEN76_00350	COG1538	Outer membrane efflux protein
BEN76_00360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN76_00365	COG0671	phosphoesterase, PA-phosphatase related
BEN76_00380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BEN76_00385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BEN76_00390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BEN76_00400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BEN76_00405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BEN76_00405	COG1648	precorrin-2 dehydrogenase activity
BEN76_00410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BEN76_00415	COG0531	amino acid
BEN76_00430	COG0321	lipoyl(octanoyl) transferase activity
BEN76_00435	COG2921	Belongs to the UPF0250 family
BEN76_00455	COG0500	methyltransferase
BEN76_00470	COG0586	Pfam SNARE associated Golgi protein
BEN76_00495	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BEN76_00500	COG0193	aminoacyl-tRNA hydrolase activity
BEN76_00505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BEN76_00510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BEN76_00535	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BEN76_00540	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BEN76_00550	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BEN76_00555	COG0358	DNA primase activity
BEN76_00565	COG0564	pseudouridine synthase activity
BEN76_00580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BEN76_00585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BEN76_00590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BEN76_00620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEN76_00620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BEN76_00635	COG2009	succinate dehydrogenase
BEN76_00640	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BEN76_00645	COG1053	succinate dehydrogenase
BEN76_00650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BEN76_00665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEN76_00670	COG0045	succinate-CoA ligase (ADP-forming) activity
BEN76_00675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BEN76_00685	COG2354	Protein conserved in bacteria
BEN76_00690	COG2321	neutral zinc metallopeptidase
BEN76_00710	COG0589	response to stress
BEN76_00715	COG3695	enzyme binding
BEN76_00730	COG0505	Belongs to the CarA family
BEN76_00750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BEN76_00755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BEN76_00760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BEN76_00775	COG1929	Belongs to the glycerate kinase type-1 family
BEN76_00790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BEN76_00810	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BEN76_00825	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BEN76_00830	COG0459	protein refolding
BEN76_00845	COG2239	Acts as a magnesium transporter
BEN76_00860	COG0741	lytic transglycosylase activity
BEN76_00865	COG0037	tRNA processing
BEN76_00875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BEN76_00880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BEN76_00890	COG1309	transcriptional regulator
BEN76_00900	COG1053	succinate dehydrogenase
BEN76_00905	COG0583	DNA-binding transcription factor activity
BEN76_00930	COG0583	DNA-binding transcription factor activity
BEN76_00935	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_00940	COG2271	Major facilitator Superfamily
BEN76_00945	COG3959	Transketolase, thiamine diphosphate binding domain
BEN76_00950	COG3958	Transketolase
BEN76_00955	COG1802	Transcriptional regulator
BEN76_00990	COG2267	carboxylic ester hydrolase activity
BEN76_01005	COG1280	lysine exporter protein (LysE YggA)
BEN76_01015	COG1309	transcriptional regulator
BEN76_01030	COG2995	paraquat-inducible protein a
BEN76_01035	COG2995	paraquat-inducible protein a
BEN76_01040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BEN76_01040	COG3008	intermembrane lipid transfer
BEN76_01065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEN76_01070	COG2828	Protein conserved in bacteria
BEN76_01155	COG2885	chlorophyll binding
BEN76_01165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEN76_01180	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_01205	COG0543	2 iron, 2 sulfur cluster binding
BEN76_01205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEN76_01210	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BEN76_01215	COG4638	Rieske (2fe-2S)
BEN76_01225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BEN76_01245	COG1115	amino acid carrier protein
BEN76_01250	COG1113	amino acid transport
BEN76_01265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BEN76_01275	COG1280	lysine exporter protein (LysE YggA)
BEN76_01280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BEN76_01310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN76_01320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BEN76_01330	COG1671	Belongs to the UPF0178 family
BEN76_01340	COG4591	ABC-type transport system involved in lipoprotein release permease component
BEN76_01345	COG1136	(ABC) transporter
BEN76_01350	COG2333	competence protein COMEC
BEN76_01350	COG0658	competence protein
BEN76_01365	COG0596	Alpha beta hydrolase
BEN76_01370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BEN76_01375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BEN76_01380	COG0628	permease
BEN76_01415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEN76_01420	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BEN76_01435	COG0823	Involved in the tonB-independent uptake of proteins
BEN76_01445	COG0848	biopolymer transport protein
BEN76_01455	COG0824	Thioesterase
BEN76_01460	COG1473	amidohydrolase
BEN76_01465	COG2255	four-way junction helicase activity
BEN76_01480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BEN76_01480	COG0047	phosphoribosylformylglycinamidine synthase activity
BEN76_01490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BEN76_01500	COG1024	Enoyl-CoA hydratase
BEN76_01505	COG1051	belongs to the nudix hydrolase family
BEN76_01505	COG1056	cytidyltransferase-related domain
BEN76_01510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BEN76_01520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BEN76_01525	COG0602	queuosine metabolic process
BEN76_01530	COG2171	N-acyltransferase activity
BEN76_01535	COG4625	pathogenesis
BEN76_01540	COG0583	DNA-binding transcription factor activity
BEN76_01545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BEN76_01550	COG4208	sulfate ABC transporter
BEN76_01555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BEN76_01565	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BEN76_01570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BEN76_01575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BEN76_01580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BEN76_01590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEN76_01595	COG0174	glutamine synthetase
BEN76_01605	COG0481	GTPase activity
BEN76_01620	COG0571	ribonuclease III activity
BEN76_01625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BEN76_01640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BEN76_01685	COG0556	nucleotide-excision repair
BEN76_01715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BEN76_01720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BEN76_01860	COG5410	chromosome segregation
BEN76_01865	COG3567	Phage-associated protein, HI1409 family
BEN76_02000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEN76_02020	COG1309	transcriptional regulator
BEN76_02045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BEN76_02060	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEN76_02060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BEN76_02075	COG1802	Transcriptional regulator
BEN76_02085	COG2267	carboxylic ester hydrolase activity
BEN76_02090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN76_02095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEN76_02100	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_02105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BEN76_02115	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_02120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BEN76_02125	COG0004	ammonium transporteR
BEN76_02130	COG0583	DNA-binding transcription factor activity
BEN76_02135	COG2814	Major facilitator Superfamily
BEN76_02150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BEN76_02155	COG2218	PFAM glutamate synthase alpha subunit domain protein
BEN76_02160	COG0069	glutamate synthase activity
BEN76_02165	COG0583	DNA-binding transcription factor activity
BEN76_02170	COG1914	H( )-stimulated, divalent metal cation uptake system
BEN76_02175	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BEN76_02180	COG4336	lyase activity
BEN76_02190	COG4770	biotin carboxylase activity
BEN76_02200	COG2031	fatty acid transporter
BEN76_02205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN76_02215	COG0583	DNA-binding transcription factor activity
BEN76_02220	COG2610	gluconate transmembrane transporter activity
BEN76_02225	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_02235	COG0535	radical SAM domain protein
BEN76_02245	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BEN76_02250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BEN76_02275	COG1741	Belongs to the pirin family
BEN76_02285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BEN76_02290	COG3739	integral membrane protein
BEN76_02295	COG0586	Pfam SNARE associated Golgi protein
BEN76_02310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BEN76_02315	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BEN76_02315	COG3608	succinylglutamate desuccinylase aspartoacylase
BEN76_02330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BEN76_02335	COG0512	Glutamine amidotransferase of anthranilate synthase
BEN76_02340	COG0697	spore germination
BEN76_02355	COG3161	chorismate lyase activity
BEN76_02360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BEN76_02375	COG2011	ABC-type metal ion transport system permease component
BEN76_02380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEN76_02390	COG0151	Belongs to the GarS family
BEN76_02395	COG0138	bifunctional purine biosynthesis protein purh
BEN76_02400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BEN76_02410	COG2264	protein methyltransferase activity
BEN76_02425	COG0445	tRNA wobble uridine modification
BEN76_02435	COG2308	Evidence 4 Homologs of previously reported genes of
BEN76_02445	COG1305	Transglutaminase-like
BEN76_02455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BEN76_02460	COG0305	Participates in initiation and elongation during chromosome replication
BEN76_02465	COG2314	TM2 domain
BEN76_02470	COG0359	binds to the 23S rRNA
BEN76_02475	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BEN76_02480	COG0360	Binds together with S18 to 16S ribosomal RNA
BEN76_02485	COG0109	protoheme IX farnesyltransferase activity
BEN76_02490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BEN76_02495	COG1845	cytochrome c oxidase, subunit III
BEN76_02500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BEN76_02505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BEN76_02520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BEN76_02525	COG3300	MHYT domain
BEN76_02525	COG5001	Diguanylate cyclase
BEN76_02530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEN76_02540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BEN76_02545	COG2890	protein-(glutamine-N5) methyltransferase activity
BEN76_02560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEN76_02565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN76_02575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BEN76_02585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BEN76_02595	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BEN76_02600	COG0477	Major facilitator Superfamily
BEN76_02605	COG0729	surface antigen
BEN76_02620	COG2217	Heavy metal translocating P-type atpase
BEN76_02625	COG1937	Protein conserved in bacteria
BEN76_02645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BEN76_02655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BEN76_02665	COG1957	nucleoside hydrolase
BEN76_02670	COG2814	Major facilitator Superfamily
BEN76_02675	COG0583	DNA-binding transcription factor activity
BEN76_02680	COG2707	UPF0756 membrane protein
BEN76_02705	COG0802	atpase or kinase
BEN76_02710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BEN76_02715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BEN76_02720	COG1923	regulation of RNA biosynthetic process
BEN76_02725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEN76_02730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BEN76_02740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BEN76_02745	COG0357	Ribosomal RNA small subunit methyltransferase G
BEN76_02750	COG1192	Involved in chromosome partitioning
BEN76_02755	COG1475	DNA binding
BEN76_02760	COG1132	(ABC) transporter
BEN76_02765	COG1663	tetraacyldisaccharide 4'-kinase activity
BEN76_02770	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BEN76_02785	COG0084	hydrolase, TatD family'
BEN76_02795	COG2165	general secretion pathway protein
BEN76_02805	COG4795	General secretion pathway protein
BEN76_02810	COG3156	type II secretion system protein K
BEN76_02820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BEN76_02830	COG0590	tRNA wobble adenosine to inosine editing
BEN76_02850	COG0776	regulation of translation
BEN76_02875	COG0284	orotidine-5'-phosphate decarboxylase activity
BEN76_02880	COG2431	L-lysine efflux transmembrane transporter activity
BEN76_02890	COG2207	Transcriptional regulator
BEN76_02895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BEN76_02900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BEN76_02930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEN76_03190	COG0582	viral genome integration into host DNA
BEN76_03205	COG1253	flavin adenine dinucleotide binding
BEN76_03210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BEN76_03215	COG0730	response to heat
BEN76_03235	COG4773	Receptor
BEN76_03240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN76_03265	COG0537	adenosine 5'-monophosphoramidase activity
BEN76_03300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BEN76_03310	COG3100	YcgL domain-containing protein
BEN76_03320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BEN76_03330	COG0517	IMP dehydrogenase activity
BEN76_03360	COG0612	Peptidase, M16
BEN76_03365	COG0552	protein localization to endoplasmic reticulum
BEN76_03385	COG3790	cyd operon protein YbgE
BEN76_03390	COG4890	Cyd operon protein YbgT
BEN76_03395	COG1294	oxidase, subunit
BEN76_03410	COG0617	tRNA 3'-terminal CCA addition
BEN76_03415	COG0281	malic enzyme
BEN76_03415	COG0280	phosphate acetyltransferase
BEN76_03420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BEN76_03425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BEN76_03430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BEN76_03445	COG2199	diguanylate cyclase activity
BEN76_03455	COG1960	acyl-CoA dehydrogenase activity
BEN76_03460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BEN76_03470	COG2175	clavaminate synthase activity
BEN76_03480	COG0024	Methionine aminopeptidase
BEN76_03485	COG0052	Belongs to the universal ribosomal protein uS2 family
BEN76_03490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BEN76_03510	COG2951	lytic endotransglycosylase activity
BEN76_03515	COG0772	Belongs to the SEDS family
BEN76_03525	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BEN76_03525	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BEN76_03530	COG0842	Transport permease protein
BEN76_03535	COG1131	(ABC) transporter
BEN76_03570	COG3038	cytochrome b561
BEN76_03590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEN76_03600	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BEN76_03620	COG3634	alkyl hydroperoxide reductase activity
BEN76_03625	COG3384	dioxygenase
BEN76_03630	COG2801	Transposase and inactivated derivatives
BEN76_03645	COG1720	tRNA m6t6A37 methyltransferase activity
BEN76_03650	COG2203	Gaf domain
BEN76_03650	COG2199	diguanylate cyclase activity
BEN76_03655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BEN76_03665	COG0745	RESPONSE REGULATOR receiver
BEN76_03670	COG0642	Histidine kinase
BEN76_03680	COG0494	nUDIX hydrolase
BEN76_03690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEN76_03695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BEN76_03700	COG3139	Protein of unknown function (DUF1315)
BEN76_03710	COG1301	dicarboxylic acid transport
BEN76_03715	COG1960	acyl-CoA dehydrogenase activity
BEN76_03720	COG0693	protein deglycase activity
BEN76_03735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BEN76_03745	COG2195	Cleaves the N-terminal amino acid of tripeptides
BEN76_03755	COG3022	response to hydroperoxide
BEN76_03760	COG1067	ATP-dependent peptidase activity
BEN76_03800	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BEN76_03805	COG1966	Carbon starvation protein
BEN76_03810	COG2879	small protein
BEN76_03815	COG0714	Associated with various cellular activities
BEN76_03845	COG3299	homolog of phage Mu protein gp47
BEN76_03930	COG4397	Mu-like prophage major head subunit gpT
BEN76_03950	COG2369	cell adhesion
BEN76_03955	COG4383	Mu-like prophage protein gp29
BEN76_03980	COG4373	Mu-like prophage FluMu protein gp28
BEN76_04110	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_04120	COG2801	Transposase and inactivated derivatives
BEN76_04125	COG0450	alkyl hydroperoxide reductase
BEN76_04130	COG1643	Atp-dependent helicase
BEN76_04155	COG0583	DNA-binding transcription factor activity
BEN76_04190	COG1278	Cold shock
BEN76_04200	COG0215	cysteine-tRNA ligase activity
BEN76_04210	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BEN76_04220	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BEN76_04225	COG1137	ATPase activity
BEN76_04235	COG1132	(ABC) transporter
BEN76_04240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN76_04275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BEN76_04285	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BEN76_04315	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BEN76_04320	COG3052	prosthetic group binding
BEN76_04380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BEN76_04390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BEN76_04395	COG0642	Histidine kinase
BEN76_04425	COG1968	undecaprenyl-diphosphatase activity
BEN76_04440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BEN76_04455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEN76_04460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BEN76_04465	COG0477	Major facilitator Superfamily
BEN76_04480	COG1902	pentaerythritol trinitrate reductase activity
BEN76_04480	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEN76_04490	COG0583	DNA-binding transcription factor activity
BEN76_04495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BEN76_04505	COG0583	DNA-binding transcription factor activity
BEN76_04545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BEN76_04560	COG4589	Belongs to the CDS family
BEN76_04575	COG2453	phosphatase
BEN76_04575	COG0671	phosphoesterase, PA-phosphatase related
BEN76_04580	COG2267	carboxylic ester hydrolase activity
BEN76_04585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BEN76_04590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BEN76_04615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BEN76_04620	COG0406	alpha-ribazole phosphatase activity
BEN76_04630	COG1346	cytolysis
BEN76_04635	COG1380	Effector of murein hydrolase LrgA
BEN76_04640	COG0583	DNA-binding transcription factor activity
BEN76_04665	COG2814	Major facilitator Superfamily
BEN76_04680	COG2814	Major facilitator Superfamily
BEN76_04695	COG0183	Belongs to the thiolase family
BEN76_04700	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEN76_04705	COG1024	Enoyl-CoA hydratase
BEN76_04710	COG1960	acyl-CoA dehydrogenase activity
BEN76_04715	COG2814	Major facilitator Superfamily
BEN76_04720	COG2814	Major facilitator Superfamily
BEN76_04730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN76_04740	COG2814	Major facilitator Superfamily
BEN76_04750	COG1960	acyl-CoA dehydrogenase activity
BEN76_04755	COG1414	Transcriptional regulator
BEN76_04760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BEN76_04765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN76_04770	COG0183	Belongs to the thiolase family
BEN76_04775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BEN76_04780	COG0596	Alpha beta hydrolase
BEN76_04785	COG2271	Major facilitator Superfamily
BEN76_04790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BEN76_04795	COG3485	protocatechuate 3,4-dioxygenase
BEN76_04800	COG3485	protocatechuate 3,4-dioxygenase
BEN76_04810	COG3420	alginic acid biosynthetic process
BEN76_04815	COG3659	wide pore channel activity
BEN76_04820	COG4993	Dehydrogenase
BEN76_04825	COG4325	translation initiation factor activity
BEN76_04830	COG1414	Transcriptional regulator
BEN76_04835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEN76_04860	COG1960	acyl-CoA dehydrogenase activity
BEN76_04875	COG1024	Enoyl-CoA hydratase
BEN76_04880	COG2814	Major facilitator Superfamily
BEN76_04890	COG1309	transcriptional regulator
BEN76_04915	COG0439	Biotin carboxylase
BEN76_04925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BEN76_04930	COG1469	GTP cyclohydrolase I activity
BEN76_04935	COG0523	cobalamin synthesis protein
BEN76_04945	COG1940	carbohydrate kinase activity
BEN76_04955	COG1027	Aspartate ammonia-lyase
BEN76_04960	COG0583	DNA-binding transcription factor activity
BEN76_04965	COG0154	amidase activity
BEN76_04995	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_05005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN76_05025	COG0411	ABC transporter
BEN76_05030	COG0410	ABC transporter
BEN76_05055	COG1294	oxidase, subunit
BEN76_05060	COG1271	oxidase subunit
BEN76_05075	COG2721	sulfolactate sulfo-lyase activity
BEN76_05080	COG2271	Major facilitator Superfamily
BEN76_05085	COG4948	Mandelate Racemase Muconate Lactonizing
BEN76_05090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEN76_05095	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_05100	COG2186	Transcriptional regulator
BEN76_05115	COG1045	serine acetyltransferase
BEN76_05120	COG4774	siderophore transport
BEN76_05130	COG0559	Belongs to the binding-protein-dependent transport system permease family
BEN76_05145	COG0410	ABC transporter
BEN76_05170	COG0668	transmembrane transport
BEN76_05175	COG3122	Protein conserved in bacteria
BEN76_05185	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BEN76_05190	COG0640	Transcriptional regulator
BEN76_05210	COG3501	Rhs element vgr protein
BEN76_05240	COG1024	Enoyl-CoA hydratase
BEN76_05245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BEN76_05250	COG1960	acyl-CoA dehydrogenase activity
BEN76_05255	COG1309	transcriptional regulator
BEN76_05260	COG0318	PFAM AMP-dependent synthetase and ligase
BEN76_05275	COG2814	Major facilitator Superfamily
BEN76_05280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BEN76_05280	COG2755	lipolytic protein G-D-S-L family
BEN76_05285	COG1733	regulation of RNA biosynthetic process
BEN76_05330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEN76_05335	COG1960	acyl-CoA dehydrogenase activity
BEN76_05340	COG1024	Enoyl-CoA hydratase
BEN76_05350	COG0477	Major facilitator Superfamily
BEN76_05355	COG4628	conserved protein (DUF2132)
BEN76_05425	COG2116	formate transmembrane transporter activity
BEN76_05430	COG1132	(ABC) transporter
BEN76_05445	COG0509	glycine decarboxylation via glycine cleavage system
BEN76_05450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BEN76_05460	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BEN76_05470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEN76_05525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BEN76_05530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BEN76_05550	COG0697	spore germination
BEN76_05560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BEN76_05565	COG4149	molybdate abc transporter
BEN76_05570	COG0725	ABC transporter, periplasmic molybdate-binding protein
BEN76_05575	COG0303	'Molybdopterin
BEN76_05580	COG0315	cyclic pyranopterin monophosphate synthase activity
BEN76_05585	COG0314	molybdopterin synthase activity
BEN76_05605	COG0243	molybdopterin cofactor binding
BEN76_05610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN76_05615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN76_05620	COG2223	nitrite transmembrane transporter activity
BEN76_05625	COG0745	RESPONSE REGULATOR receiver
BEN76_05630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEN76_05630	COG1116	anion transmembrane transporter activity
BEN76_05635	COG0243	molybdopterin cofactor binding
BEN76_05640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BEN76_05650	COG3698	Phosphodiester glycosidase
BEN76_05660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEN76_05670	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN76_05680	COG0697	spore germination
BEN76_05700	COG2801	Transposase and inactivated derivatives
BEN76_05715	COG0424	maF-like protein
BEN76_05720	COG2851	Citrate transporter
BEN76_05725	COG2850	peptidyl-arginine hydroxylation
BEN76_05730	COG0069	glutamate synthase activity
BEN76_05745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BEN76_05750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEN76_05755	COG1454	alcohol dehydrogenase
BEN76_05760	COG0824	Thioesterase
BEN76_05795	COG0183	Belongs to the thiolase family
BEN76_05805	COG0583	DNA-binding transcription factor activity
BEN76_05810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BEN76_05820	COG3135	benzoate transporter
BEN76_05830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BEN76_05845	COG1714	RDD family
BEN76_05850	COG0024	Methionine aminopeptidase
BEN76_05855	COG1114	Component of the transport system for branched-chain amino acids
BEN76_05870	COG1105	Belongs to the carbohydrate kinase PfkB family
BEN76_05875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEN76_05875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BEN76_05875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEN76_05885	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BEN76_05900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BEN76_05910	COG0148	phosphopyruvate hydratase activity
BEN76_05915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BEN76_05920	COG0504	CTP synthase activity
BEN76_05930	COG0589	response to stress
BEN76_05945	COG0308	aminopeptidase N
BEN76_05960	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BEN76_05975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN76_05980	COG1454	alcohol dehydrogenase
BEN76_06000	COG0505	Belongs to the CarA family
BEN76_06040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BEN76_06055	COG2353	YceI-like domain
BEN76_06060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BEN76_06065	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BEN76_06085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BEN76_06090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BEN76_06090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BEN76_06100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BEN76_06215	COG1063	alcohol dehydrogenase
BEN76_06220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEN76_06225	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEN76_06230	COG0022	dehydrogenase e1 component
BEN76_06235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BEN76_06240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BEN76_06255	COG0640	Transcriptional regulator
BEN76_06265	COG0798	PFAM Bile acid sodium symporter
BEN76_06270	COG0431	NADPH-dependent FMN reductase
BEN76_06275	COG0786	glutamate:sodium symporter activity
BEN76_06280	COG0745	RESPONSE REGULATOR receiver
BEN76_06285	COG5002	protein histidine kinase activity
BEN76_06295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEN76_06300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN76_06320	COG2130	NADP-dependent
BEN76_06365	COG1595	DNA-templated transcription, initiation
BEN76_06375	COG3220	belongs to the UPF0276 family
BEN76_06405	COG0217	transcriptional regulatory protein
BEN76_06420	COG1126	abc transporter atp-binding protein
BEN76_06425	COG0765	amino acid transport
BEN76_06430	COG0765	amino acid transport
BEN76_06460	COG1464	Belongs to the NlpA lipoprotein family
BEN76_06465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEN76_06470	COG2011	ABC-type metal ion transport system permease component
BEN76_06475	COG0012	GTP binding
BEN76_06495	COG1979	alcohol dehydrogenase
BEN76_06520	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BEN76_06525	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BEN76_06530	COG0436	Aminotransferase
BEN76_06545	COG1917	Cupin 2, conserved barrel domain protein
BEN76_06545	COG2207	Transcriptional regulator
BEN76_06550	COG0386	Belongs to the glutathione peroxidase family
BEN76_06555	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BEN76_06560	COG0436	Aminotransferase
BEN76_06580	COG1045	serine acetyltransferase
BEN76_06600	COG3706	GGDEF domain
BEN76_06605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BEN76_06610	COG0596	Alpha beta hydrolase
BEN76_06620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BEN76_06630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEN76_06635	COG2186	Transcriptional regulator
BEN76_06650	COG0531	amino acid
BEN76_06675	COG1733	regulation of RNA biosynthetic process
BEN76_06680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BEN76_06710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN76_06715	COG0183	Belongs to the thiolase family
BEN76_06720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BEN76_06725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BEN76_06730	COG4829	muconolactone delta-isomerase
BEN76_06735	COG4948	Mandelate Racemase Muconate Lactonizing
BEN76_06740	COG0583	DNA-binding transcription factor activity
BEN76_06745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BEN76_06750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BEN76_06755	COG3485	protocatechuate 3,4-dioxygenase
BEN76_06760	COG3135	benzoate transporter
BEN76_06765	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_06770	COG0633	Ferredoxin
BEN76_06770	COG0543	2 iron, 2 sulfur cluster binding
BEN76_06775	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BEN76_06780	COG4638	Rieske (2fe-2S)
BEN76_06785	COG0583	DNA-binding transcription factor activity
BEN76_06790	COG2814	Major facilitator Superfamily
BEN76_06800	COG3284	Transcriptional regulator
BEN76_06845	COG0745	RESPONSE REGULATOR receiver
BEN76_06860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BEN76_06865	COG2040	homocysteine
BEN76_06870	COG0531	amino acid
BEN76_06890	COG1960	acyl-CoA dehydrogenase activity
BEN76_06895	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEN76_06900	COG2207	Transcriptional regulator
BEN76_06905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEN76_06910	COG0776	regulation of translation
BEN76_06935	COG0822	iron-sulfur transferase activity
BEN76_06940	COG0316	Belongs to the HesB IscA family
BEN76_06945	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BEN76_06950	COG0443	Heat shock 70 kDa protein
BEN76_06955	COG0633	Ferredoxin
BEN76_06970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BEN76_06985	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BEN76_06990	COG0702	epimerase
BEN76_06995	COG0268	Binds directly to 16S ribosomal RNA
BEN76_07005	COG1218	3'(2'),5'-bisphosphate nucleotidase
BEN76_07010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BEN76_07015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BEN76_07020	COG2137	regulation of response to DNA damage stimulus
BEN76_07035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN76_07040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BEN76_07045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BEN76_07070	COG0575	Belongs to the CDS family
BEN76_07075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BEN76_07080	COG0233	cytoplasmic translational termination
BEN76_07085	COG0528	UMP kinase activity
BEN76_07090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BEN76_07095	COG3852	Histidine kinase
BEN76_07110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BEN76_07120	COG0542	response to heat
BEN76_07125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BEN76_07135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BEN76_07145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BEN76_07150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BEN76_07155	COG0569	domain protein
BEN76_07160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BEN76_07175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BEN76_07185	COG1585	Membrane protein implicated in regulation of membrane protease activity
BEN76_07190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEN76_07195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BEN76_07200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BEN76_07220	COG1522	sequence-specific DNA binding
BEN76_07225	COG1113	amino acid transport
BEN76_07245	COG1301	dicarboxylic acid transport
BEN76_07285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BEN76_07290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BEN76_07305	COG4783	chaperone-mediated protein folding
BEN76_07335	COG0167	dihydroorotate dehydrogenase activity
BEN76_07355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BEN76_07360	COG0778	Nitroreductase
BEN76_07370	COG0513	Belongs to the DEAD box helicase family
BEN76_07390	COG2363	Small membrane protein
BEN76_07400	COG2022	thiamine diphosphate biosynthetic process
BEN76_07415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BEN76_07430	COG0540	Belongs to the ATCase OTCase family
BEN76_07435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BEN76_07435	COG0116	Belongs to the methyltransferase superfamily
BEN76_07445	COG0129	dihydroxy-acid dehydratase activity
BEN76_07460	COG1113	amino acid transport
BEN76_07475	COG1765	OsmC-like protein
BEN76_07485	COG0667	Aldo Keto reductase
BEN76_07490	COG0501	Belongs to the peptidase M48B family
BEN76_07500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BEN76_07505	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BEN76_07510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BEN76_07515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BEN76_07520	COG0527	aspartate kinase activity
BEN76_07530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BEN76_07540	COG3038	cytochrome b561
BEN76_07545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BEN76_07550	COG2252	PERMEase
BEN76_07565	COG0659	secondary active sulfate transmembrane transporter activity
BEN76_07580	COG0589	response to stress
BEN76_07595	COG3634	alkyl hydroperoxide reductase activity
BEN76_07605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BEN76_07610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BEN76_07615	COG0583	DNA-binding transcription factor activity
BEN76_07625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BEN76_07635	COG1686	Belongs to the peptidase S11 family
BEN76_07640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BEN76_07645	COG1476	TRANSCRIPTIONal
BEN76_07660	COG0482	sulfurtransferase activity
BEN76_07665	COG2915	High frequency lysogenization protein hflD homolog
BEN76_07675	COG0616	signal peptide processing
BEN76_07680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BEN76_07690	COG0573	inorganic phosphate transmembrane transporter activity
BEN76_07695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BEN76_07705	COG3327	negative regulation of DNA-templated transcription, initiation
BEN76_07710	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BEN76_07715	COG1024	Enoyl-CoA hydratase
BEN76_07720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEN76_07725	COG2151	metal-sulfur cluster biosynthetic enzyme
BEN76_07730	COG3396	Phenylacetate-CoA oxygenase
BEN76_07735	COG3460	Phenylacetate-CoA oxygenase
BEN76_07740	COG3396	Phenylacetate-CoA oxygenase
BEN76_07745	COG2030	dehydratase
BEN76_07745	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_07750	COG1113	amino acid transport
BEN76_07755	COG3961	Belongs to the TPP enzyme family
BEN76_07760	COG1522	sequence-specific DNA binding
BEN76_07765	COG0076	glutamate decarboxylase activity
BEN76_07770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BEN76_07795	COG0783	Belongs to the Dps family
BEN76_07805	COG0564	pseudouridine synthase activity
BEN76_07815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BEN76_07820	COG0352	thiamine-phosphate diphosphorylase activity
BEN76_07835	COG3025	triphosphatase activity
BEN76_07850	COG0612	Peptidase, M16
BEN76_07855	COG0038	chloride channel
BEN76_07870	COG1187	pseudouridine synthase activity
BEN76_07875	COG2351	hydroxyisourate hydrolase activity
BEN76_07880	COG2801	Transposase and inactivated derivatives
BEN76_07900	COG1686	Belongs to the peptidase S11 family
BEN76_07910	COG0415	Belongs to the DNA photolyase family
BEN76_07930	COG0010	Belongs to the arginase family
BEN76_07960	COG2188	Transcriptional regulator
BEN76_07965	COG2807	transmembrane transport
BEN76_07970	COG0583	DNA-binding transcription factor activity
BEN76_07985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEN76_07990	COG2814	Major facilitator Superfamily
BEN76_07995	COG1278	Cold shock
BEN76_08010	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEN76_08010	COG1902	pentaerythritol trinitrate reductase activity
BEN76_08015	COG0697	spore germination
BEN76_08020	COG0583	DNA-binding transcription factor activity
BEN76_08030	COG0418	dihydroorotase activity
BEN76_08035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEN76_08050	COG0833	amino acid
BEN76_08080	COG4172	Belongs to the ABC transporter superfamily
BEN76_08085	COG4239	(ABC) transporter, permease
BEN76_08090	COG4174	ABC transporter (Permease)
BEN76_08095	COG4166	transmembrane transport
BEN76_08100	COG1388	LysM domain
BEN76_08100	COG1388	LysM domain
BEN76_08100	COG0741	lytic transglycosylase activity
BEN76_08100	COG0741	lytic transglycosylase activity
BEN76_08105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEN76_08130	COG0792	nuclease activity
BEN76_08150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEN76_08155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEN76_08160	COG0006	proline dipeptidase activity
BEN76_08175	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BEN76_08190	COG0463	Glycosyl transferase, family 2
BEN76_08200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BEN76_08205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BEN76_08220	COG3384	dioxygenase
BEN76_08230	COG2878	Part of a membrane complex involved in electron transport
BEN76_08235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BEN76_08240	COG0563	adenylate kinase activity
BEN76_08255	COG0768	penicillin binding
BEN76_08260	COG0742	ribosomal rna small subunit methyltransferase
BEN76_08280	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BEN76_08290	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BEN76_08295	COG0804	urea catabolic process
BEN76_08300	COG0832	Belongs to the urease beta subunit family
BEN76_08305	COG0831	urea catabolic process
BEN76_08310	COG0829	nickel cation binding
BEN76_08335	COG1253	flavin adenine dinucleotide binding
BEN76_08345	COG2851	Citrate transporter
BEN76_08360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BEN76_08365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BEN76_08375	COG1773	rubredoxin
BEN76_08380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEN76_08390	COG0583	DNA-binding transcription factor activity
BEN76_08400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEN76_08410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BEN76_08415	COG4181	ATPase activity
BEN76_08455	COG3048	D-serine ammonia-lyase activity
BEN76_08460	COG0306	phosphate transporter
BEN76_08485	COG2223	nitrite transmembrane transporter activity
BEN76_08495	COG0242	peptide deformylase activity
BEN76_08500	COG0561	phosphatase activity
BEN76_08525	COG1215	transferase activity, transferring glycosyl groups
BEN76_08530	COG0726	polysaccharide deacetylase
BEN76_08530	COG1649	PFAM Uncharacterised BCR, COG1649
BEN76_08540	COG4681	YaeQ
BEN76_08550	COG0523	cobalamin synthesis protein
BEN76_08560	COG1607	acyl-coa hydrolase
BEN76_08575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BEN76_08580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BEN76_08585	COG1309	transcriptional regulator
BEN76_08590	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_08595	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BEN76_08600	COG0579	oxidoreductase
BEN76_08640	COG0028	Belongs to the TPP enzyme family
BEN76_08650	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BEN76_08655	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_08660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN76_08670	COG2271	Major facilitator Superfamily
BEN76_08685	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_08700	COG2146	nitrite reductase [NAD(P)H] activity
BEN76_08705	COG1414	Transcriptional regulator
BEN76_08725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEN76_08750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEN76_08755	COG1120	ATPase activity
BEN76_08760	COG1802	Transcriptional regulator
BEN76_08765	COG0583	DNA-binding transcription factor activity
BEN76_08785	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_08790	COG2814	Major facilitator Superfamily
BEN76_08810	COG0534	Mate efflux family protein
BEN76_08825	COG4774	siderophore transport
BEN76_08845	COG0019	diaminopimelate decarboxylase activity
BEN76_08850	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BEN76_08855	COG1021	2,3-dihydroxybenzoate-AMP ligase
BEN76_08860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEN76_08875	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_08880	COG1535	isochorismatase
BEN76_08880	COG3433	isochorismatase activity
BEN76_08885	COG1169	isochorismate synthase
BEN76_08930	COG3210	domain, Protein
BEN76_08935	COG2831	hemolysin activation secretion protein
BEN76_08945	COG0477	Major facilitator Superfamily
BEN76_08965	COG2084	Dehydrogenase
BEN76_08975	COG1473	amidohydrolase
BEN76_08990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BEN76_08995	COG0405	Gamma-glutamyltransferase
BEN76_09000	COG2814	Major facilitator Superfamily
BEN76_09005	COG1566	PFAM secretion protein HlyD family protein
BEN76_09010	COG2050	protein possibly involved in aromatic compounds catabolism
BEN76_09025	COG1090	epimerase
BEN76_09040	COG0420	3'-5' exonuclease activity
BEN76_09055	COG1968	undecaprenyl-diphosphatase activity
BEN76_09075	COG0735	belongs to the Fur family
BEN76_09080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BEN76_09085	COG2914	Belongs to the UPF0125 (RnfH) family
BEN76_09095	COG0121	glutamine amidotransferase
BEN76_09105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BEN76_09110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEN76_09125	COG2885	chlorophyll binding
BEN76_09130	COG0204	Acyl-transferase
BEN76_09140	COG0850	regulation of cytokinetic process
BEN76_09150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BEN76_09165	COG1674	ftsk spoiiie
BEN76_09165	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BEN76_09170	COG0492	ferredoxin-NADP+ reductase activity
BEN76_09175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BEN76_09180	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BEN76_09185	COG0456	acetyltransferase
BEN76_09195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BEN76_09205	COG0049	tRNA binding
BEN76_09210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BEN76_09240	COG0351	phosphomethylpyrimidine kinase
BEN76_09240	COG0352	thiamine-phosphate diphosphorylase activity
BEN76_09240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BEN76_09245	COG1652	LysM domain
BEN76_09255	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_09260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BEN76_09265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BEN76_09270	COG1399	metal-binding, possibly nucleic acid-binding protein
BEN76_09275	COG3101	peptidyl-lysine hydroxylation
BEN76_09280	COG0009	L-threonylcarbamoyladenylate synthase
BEN76_09290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BEN76_09295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BEN76_09310	COG4106	trans-aconitate 2-methyltransferase activity
BEN76_09330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BEN76_09350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BEN76_09360	COG1196	nuclear chromosome segregation
BEN76_09370	COG0730	response to heat
BEN76_09380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BEN76_09385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BEN76_09395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEN76_09405	COG0560	Phosphoserine phosphatase
BEN76_09415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEN76_09420	COG1530	ribonuclease E activity
BEN76_09425	COG0424	maF-like protein
BEN76_09435	COG1792	Involved in formation and maintenance of cell shape
BEN76_09440	COG1077	Cell shape determining protein MreB Mrl
BEN76_09445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEN76_09450	COG0154	amidase activity
BEN76_09455	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEN76_09510	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BEN76_09515	COG0693	protein deglycase activity
BEN76_09520	COG1752	Esterase of the alpha-beta hydrolase superfamily
BEN76_09525	COG1115	amino acid carrier protein
BEN76_09530	COG0786	glutamate:sodium symporter activity
BEN76_09540	COG2814	Major facilitator Superfamily
BEN76_09545	COG1289	transmembrane transporter activity
BEN76_09605	COG2832	Protein of unknown function (DUF454)
BEN76_09620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEN76_09625	COG2198	Histidine kinase
BEN76_09625	COG0643	Histidine kinase
BEN76_09630	COG0840	transmembrane signaling receptor activity
BEN76_09665	COG0442	prolyl-tRNA aminoacylation
BEN76_09700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BEN76_09705	COG0489	protein tyrosine kinase activity
BEN76_09720	COG3248	Nucleoside-binding outer membrane protein
BEN76_09725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEN76_09725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEN76_09740	COG2233	PERMEase
BEN76_09745	COG0833	amino acid
BEN76_09755	COG3724	N-succinylarginine dihydrolase activity
BEN76_09760	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_09775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEN76_09790	COG1280	lysine exporter protein (LysE YggA)
BEN76_09795	COG2226	methyltransferase
BEN76_09825	COG2081	HI0933 family
BEN76_09835	COG0668	transmembrane transport
BEN76_09855	COG0583	DNA-binding transcription factor activity
BEN76_09860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BEN76_09870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN76_09875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEN76_09880	COG0713	ATP synthesis coupled electron transport
BEN76_09890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN76_09895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BEN76_09905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BEN76_09915	COG0649	NAD binding
BEN76_09915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN76_09920	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN76_09925	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BEN76_09930	COG2199	diguanylate cyclase activity
BEN76_09940	COG2205	protein histidine kinase activity
BEN76_09945	COG0745	RESPONSE REGULATOR receiver
BEN76_09950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEN76_09950	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BEN76_09955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEN76_09960	COG3422	double-strand break repair
BEN76_09965	COG0494	nUDIX hydrolase
BEN76_09970	COG2824	Alkylphosphonate utilization operon protein PhnA
BEN76_09985	COG0564	pseudouridine synthase activity
BEN76_09995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BEN76_10005	COG1953	Uracil, thiamine, allantoin
BEN76_10020	COG1902	pentaerythritol trinitrate reductase activity
BEN76_10025	COG4772	TonB-dependent receptor
BEN76_10030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BEN76_10035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEN76_10045	COG1970	mechanosensitive ion channel activity
BEN76_10055	COG2233	PERMEase
BEN76_10060	COG2813	Specifically methylates the guanine in position
BEN76_10065	COG0833	amino acid
BEN76_10070	COG2885	chlorophyll binding
BEN76_10070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BEN76_10080	COG0183	Belongs to the thiolase family
BEN76_10105	COG2132	Multicopper oxidase
BEN76_10115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BEN76_10135	COG0742	ribosomal rna small subunit methyltransferase
BEN76_10140	COG1214	PFAM Peptidase M22, glycoprotease
BEN76_10195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BEN76_10200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BEN76_10210	COG2801	Transposase and inactivated derivatives
BEN76_10215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BEN76_10220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BEN76_10280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEN76_10285	COG1846	Transcriptional regulator
BEN76_10290	COG1764	response to oxidative stress
BEN76_10330	COG0037	tRNA processing
BEN76_10360	COG0776	regulation of translation
BEN76_10365	COG0072	phenylalanine-tRNA ligase activity
BEN76_10370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BEN76_10385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BEN76_10390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BEN76_10405	COG1238	metal cluster binding
BEN76_10410	COG0625	glutathione transferase activity
BEN76_10420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BEN76_10425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BEN76_10430	COG0318	PFAM AMP-dependent synthetase and ligase
BEN76_10435	COG3028	Belongs to the UPF0307 family
BEN76_10440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEN76_10445	COG1660	Displays ATPase and GTPase activities
BEN76_10450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BEN76_10455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BEN76_10460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BEN76_10465	COG0617	tRNA 3'-terminal CCA addition
BEN76_10470	COG1596	polysaccharide export
BEN76_10470	COG1555	photosystem II stabilization
BEN76_10475	COG3956	TIGRFAM MazG family protein
BEN76_10485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BEN76_10490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BEN76_10505	COG2205	protein histidine kinase activity
BEN76_10505	COG5002	protein histidine kinase activity
BEN76_10505	COG0784	Response regulator, receiver
BEN76_10515	COG2084	Dehydrogenase
BEN76_10520	COG3622	Belongs to the hyi family
BEN76_10535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BEN76_10540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BEN76_10545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BEN76_10555	COG0789	Transcriptional regulator
BEN76_10565	COG2814	Major facilitator Superfamily
BEN76_10570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEN76_10580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BEN76_10590	COG0084	hydrolase, TatD family'
BEN76_10605	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BEN76_10615	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BEN76_10625	COG0028	Belongs to the TPP enzyme family
BEN76_10635	COG0495	leucyl-tRNA aminoacylation
BEN76_10650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEN76_10655	COG1136	(ABC) transporter
BEN76_10655	COG0577	efflux transmembrane transporter activity
BEN76_10660	COG1538	Outer membrane efflux protein
BEN76_10670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BEN76_10675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BEN76_10680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BEN76_10690	COG3501	Rhs element vgr protein
BEN76_10705	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BEN76_10710	COG1162	GTPase activity
BEN76_10725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BEN76_10730	COG3783	Cytochrome b(562)
BEN76_10735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BEN76_10740	COG2003	Belongs to the UPF0758 family
BEN76_10745	COG3781	membrane
BEN76_10760	COG2350	Protein conserved in bacteria
BEN76_10770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BEN76_10770	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BEN76_10780	COG1666	GTP binding
BEN76_10790	COG1607	acyl-coa hydrolase
BEN76_10805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEN76_10805	COG3453	Protein conserved in bacteria
BEN76_10815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEN76_10855	COG1183	phosphatidylcholine synthase activity
BEN76_10860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BEN76_10890	COG0741	lytic transglycosylase activity
BEN76_10890	COG0739	heme binding
BEN76_10890	COG1196	nuclear chromosome segregation
BEN76_10895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BEN76_10900	COG1702	phosphate starvation-inducible protein PhoH
BEN76_10905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BEN76_10920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEN76_10940	COG1295	ribonuclease BN
BEN76_10945	COG0583	DNA-binding transcription factor activity
BEN76_10950	COG2814	Major facilitator Superfamily
BEN76_10955	COG0179	Fumarylacetoacetate (FAA) hydrolase
BEN76_10990	COG0557	exoribonuclease II activity
BEN76_10995	COG0339	signal peptide processing
BEN76_11000	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BEN76_11025	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BEN76_11030	COG1960	acyl-CoA dehydrogenase activity
BEN76_11035	COG2072	flavoprotein involved in K transport
BEN76_11045	COG0202	RNA polymerase activity
BEN76_11050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BEN76_11055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BEN76_11065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BEN76_11075	COG0200	Binds to the 23S rRNA
BEN76_11080	COG1841	ribosomal large subunit assembly
BEN76_11085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BEN76_11090	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BEN76_11095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BEN76_11100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BEN76_11110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BEN76_11115	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BEN76_11120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BEN76_11125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BEN76_11135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BEN76_11140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BEN76_11150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BEN76_11155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BEN76_11160	COG0089	rRNA binding
BEN76_11165	COG0088	Forms part of the polypeptide exit tunnel
BEN76_11170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BEN76_11175	COG0051	transcription antitermination factor activity, RNA binding
BEN76_11180	COG0505	Belongs to the CarA family
BEN76_11190	COG0433	COG0433 Predicted ATPase
BEN76_11195	COG1017	nitric oxide dioxygenase activity
BEN76_11195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEN76_11200	COG1959	2 iron, 2 sulfur cluster binding
BEN76_11215	COG1301	dicarboxylic acid transport
BEN76_11220	COG1946	Acyl-CoA thioesterase
BEN76_11225	COG2937	Belongs to the GPAT DAPAT family
BEN76_11245	COG1040	competence protein
BEN76_11260	COG0598	Magnesium transport protein CorA
BEN76_11280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BEN76_11285	COG1127	ABC transporter
BEN76_11290	COG0513	Belongs to the DEAD box helicase family
BEN76_11300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BEN76_11305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BEN76_11310	COG0408	coproporphyrinogen oxidase activity
BEN76_11320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEN76_11325	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BEN76_11335	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BEN76_11345	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BEN76_11345	COG0644	oxidoreductase
BEN76_11355	COG1960	acyl-CoA dehydrogenase activity
BEN76_11365	COG1983	PspC domain protein
BEN76_11380	COG0752	glycyl-tRNA synthetase alpha subunit
BEN76_11385	COG0751	glycine-tRNA ligase activity
BEN76_11395	COG3104	oligopeptide transport
BEN76_11405	COG0583	DNA-binding transcription factor activity
BEN76_11420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BEN76_11435	COG0656	L-ascorbic acid biosynthetic process
BEN76_11460	COG1192	Involved in chromosome partitioning
BEN76_11465	COG0628	permease
BEN76_11475	COG1289	transmembrane transporter activity
BEN76_11485	COG2249	NAD(P)H dehydrogenase (quinone) activity
BEN76_11490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BEN76_11495	COG2131	deaminase
BEN76_11520	COG0277	FAD linked oxidase domain protein
BEN76_11525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BEN76_11530	COG5006	permease, DMT superfamily
BEN76_11550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BEN76_11555	COG5380	lipid catabolic process
BEN76_11560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BEN76_11565	COG0335	large ribosomal subunit rRNA binding
BEN76_11570	COG0336	Belongs to the RNA methyltransferase TrmD family
BEN76_11575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BEN76_11580	COG0228	four-way junction DNA binding
BEN76_11620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BEN76_11625	COG0194	GDP metabolic process
BEN76_11630	COG1758	RNA polymerase activity
BEN76_11640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BEN76_11660	COG3307	-O-antigen
BEN76_11665	COG4969	Belongs to the N-Me-Phe pilin family
BEN76_11670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEN76_11675	COG1982	Orn Lys Arg decarboxylase major
BEN76_11680	COG1181	Belongs to the D-alanine--D-alanine ligase family
BEN76_11695	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BEN76_11700	COG1704	LemA family
BEN76_11710	COG0493	'glutamate synthase
BEN76_11715	COG0069	glutamate synthase activity
BEN76_11715	COG0070	glutamate synthase
BEN76_11715	COG0067	glutamate synthase
BEN76_11725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BEN76_11730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BEN76_11765	COG2226	methyltransferase
BEN76_11770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BEN76_11775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BEN76_11780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BEN76_11795	COG0275	rRNA processing
BEN76_11810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEN76_11855	COG0488	(ABC) transporter
BEN76_11860	COG0028	Belongs to the TPP enzyme family
BEN76_11870	COG4221	oxidoreductase activity
BEN76_11885	COG0745	RESPONSE REGULATOR receiver
BEN76_11890	COG2205	protein histidine kinase activity
BEN76_11895	COG0427	acetyl-CoA hydrolase
BEN76_11925	COG0131	Imidazoleglycerol-phosphate dehydratase
BEN76_11930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BEN76_11940	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BEN76_11945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEN76_11950	COG1132	(ABC) transporter
BEN76_11965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEN76_11970	COG0107	imidazoleglycerol-phosphate synthase activity
BEN76_12000	COG3158	transport of potassium into the cell
BEN76_12030	COG1401	restriction endodeoxyribonuclease activity
BEN76_12065	COG0475	glutathione-regulated potassium exporter activity
BEN76_12065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BEN76_12085	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BEN76_12095	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_12100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BEN76_12120	COG2814	Major facilitator Superfamily
BEN76_12130	COG0352	thiamine-phosphate diphosphorylase activity
BEN76_12130	COG0351	phosphomethylpyrimidine kinase
BEN76_12130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BEN76_12150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BEN76_12155	COG3706	GGDEF domain
BEN76_12165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BEN76_12180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEN76_12185	COG3162	membrane
BEN76_12190	COG2205	protein histidine kinase activity
BEN76_12190	COG0784	Response regulator, receiver
BEN76_12215	COG1335	isochorismatase
BEN76_12225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEN76_12230	COG3152	Membrane
BEN76_12235	COG0668	transmembrane transport
BEN76_12245	COG1519	Transferase
BEN76_12250	COG1902	pentaerythritol trinitrate reductase activity
BEN76_12255	COG0640	Transcriptional regulator
BEN76_12270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BEN76_12275	COG0259	pyridoxamine-phosphate oxidase activity
BEN76_12280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEN76_12295	COG2119	membrane
BEN76_12300	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEN76_12320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BEN76_12325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BEN76_12335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BEN76_12340	COG1181	Belongs to the D-alanine--D-alanine ligase family
BEN76_12345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BEN76_12350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BEN76_12355	COG0189	ligase activity
BEN76_12360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BEN76_12380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN76_12385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BEN76_12395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BEN76_12400	COG0708	Exodeoxyribonuclease III
BEN76_12420	COG3706	GGDEF domain
BEN76_12465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEN76_12470	COG4266	Belongs to the allantoicase family
BEN76_12475	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BEN76_12495	COG3150	esterase
BEN76_12505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BEN76_12510	COG2918	glutathione biosynthetic process
BEN76_12525	COG2733	membrane
BEN76_12530	COG0436	Aminotransferase
BEN76_12535	COG0534	Mate efflux family protein
BEN76_12560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BEN76_12570	COG0688	phosphatidylethanolamine metabolic process
BEN76_12580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BEN76_12585	COG1490	D-aminoacyl-tRNA deacylase activity
BEN76_12605	COG3830	Belongs to the UPF0237 family
BEN76_12605	COG0560	Phosphoserine phosphatase
BEN76_12625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BEN76_12630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BEN76_12635	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BEN76_12640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BEN76_12645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BEN76_12650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BEN76_12695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEN76_12700	COG4605	iron ion homeostasis
BEN76_12705	COG4604	ABC transporter, ATP-binding protein
BEN76_12710	COG4607	ABC-type enterochelin transport system periplasmic component
BEN76_12715	COG4774	siderophore transport
BEN76_12720	COG0735	belongs to the Fur family
BEN76_12730	COG1196	nuclear chromosome segregation
BEN76_12735	COG1074	ATP-dependent DNA helicase activity
BEN76_12745	COG0625	glutathione transferase activity
BEN76_12760	COG1683	Conserved Protein
BEN76_12785	COG0385	Bile acid
BEN76_12790	COG1335	isochorismatase
BEN76_12795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEN76_12805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BEN76_12810	COG2801	Transposase and inactivated derivatives
BEN76_12825	COG0765	amino acid transport
BEN76_12830	COG0765	amino acid transport
BEN76_12840	COG2116	formate transmembrane transporter activity
BEN76_12855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BEN76_12865	COG2133	pyrroloquinoline quinone binding
BEN76_12880	COG2983	Belongs to the UPF0260 family
BEN76_12885	COG5487	UPF0391 membrane protein
BEN76_12915	COG2818	Glycosylase
BEN76_12920	COG1064	alcohol dehydrogenase
BEN76_12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEN76_12935	COG0583	DNA-binding transcription factor activity
BEN76_12940	COG0656	L-ascorbic acid biosynthetic process
BEN76_12945	COG2814	Major facilitator Superfamily
BEN76_12955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BEN76_12960	COG0484	heat shock protein binding
BEN76_12985	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BEN76_12990	COG2233	PERMEase
BEN76_13005	COG1252	NADH dehydrogenase
BEN76_13015	COG0129	dihydroxy-acid dehydratase activity
BEN76_13020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BEN76_13030	COG0428	transporter
BEN76_13040	COG0733	neurotransmitter:sodium symporter activity
BEN76_13050	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_13060	COG0693	protein deglycase activity
BEN76_13090	COG0737	Belongs to the 5'-nucleotidase family
BEN76_13100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BEN76_13105	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BEN76_13110	COG0316	Belongs to the HesB IscA family
BEN76_13125	COG0488	(ABC) transporter
BEN76_13130	COG0187	DNA topoisomerase II activity
BEN76_13135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BEN76_13140	COG0592	DNA-directed DNA polymerase activity
BEN76_13145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BEN76_13150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BEN76_13155	COG0594	ribonuclease P activity
BEN76_13160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BEN76_13165	COG0706	membrane insertase activity
BEN76_13170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BEN76_13205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BEN76_13220	COG0402	S-adenosylhomocysteine deaminase activity
BEN76_13230	COG0861	Integral membrane protein TerC family
BEN76_13235	COG0671	phosphoesterase, PA-phosphatase related
BEN76_13240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BEN76_13260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BEN76_13265	COG2951	lytic endotransglycosylase activity
BEN76_13285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BEN76_13315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BEN76_13355	COG1047	Peptidyl-prolyl cis-trans
BEN76_13360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BEN76_13365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BEN76_13370	COG0196	riboflavin kinase activity
BEN76_13375	COG0596	Alpha beta hydrolase
BEN76_13380	COG1309	transcriptional regulator
BEN76_13385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEN76_13390	COG1335	isochorismatase
BEN76_13395	COG0251	oxidation-reduction process
BEN76_13400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEN76_13405	COG2233	PERMEase
BEN76_13410	COG1116	anion transmembrane transporter activity
BEN76_13415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BEN76_13420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEN76_13425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEN76_13430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEN76_13435	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BEN76_13435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BEN76_13450	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_13460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BEN76_13480	COG1017	nitric oxide dioxygenase activity
BEN76_13480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEN76_13490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BEN76_13505	COG3023	N-Acetylmuramoyl-L-alanine amidase
BEN76_13535	COG1596	polysaccharide export
BEN76_13540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BEN76_13555	COG2244	polysaccharide biosynthetic process
BEN76_13560	COG1088	dTDP-glucose 4,6-dehydratase activity
BEN76_13565	COG1091	dTDP-4-dehydrorhamnose reductase activity
BEN76_13600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BEN76_13625	COG0438	transferase activity, transferring glycosyl groups
BEN76_13630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BEN76_13640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BEN76_13655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEN76_13665	COG0166	Belongs to the GPI family
BEN76_13670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BEN76_13675	COG3307	-O-antigen
BEN76_13680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEN76_13690	COG1620	l-lactate permease
BEN76_13695	COG2186	Transcriptional regulator
BEN76_13705	COG0277	FAD linked oxidase domain protein
BEN76_13725	COG1113	amino acid transport
BEN76_13740	COG1522	sequence-specific DNA binding
BEN76_13745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BEN76_13755	COG0251	oxidation-reduction process
BEN76_13760	COG1113	amino acid transport
BEN76_13790	COG5007	Belongs to the BolA IbaG family
BEN76_13800	COG1192	Involved in chromosome partitioning
BEN76_13815	COG0586	Pfam SNARE associated Golgi protein
BEN76_13820	COG2259	Doxx family
BEN76_13825	COG3111	PFAM Bacterial OB fold (BOF) protein
BEN76_13830	COG0519	Catalyzes the synthesis of GMP from XMP
BEN76_13830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BEN76_13870	COG0018	arginyl-trna synthetase
BEN76_13875	COG0281	malic enzyme
BEN76_13885	COG3179	chitinase
BEN76_13905	COG2837	iron assimilation
BEN76_13915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEN76_13920	COG1121	(ABC) transporter
BEN76_13940	COG0356	it plays a direct role in the translocation of protons across the membrane
BEN76_13950	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BEN76_13955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BEN76_13960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BEN76_13965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BEN76_13970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BEN76_13980	COG0676	glucose-6-phosphate 1-epimerase activity
BEN76_13990	COG0386	Belongs to the glutathione peroxidase family
BEN76_14005	COG1309	transcriptional regulator
BEN76_14010	COG0697	spore germination
BEN76_14025	COG0009	L-threonylcarbamoyladenylate synthase
BEN76_14030	COG0758	DNA mediated transformation
BEN76_14035	COG1652	LysM domain
BEN76_14065	COG1309	transcriptional regulator
BEN76_14095	COG0584	glycerophosphoryl diester phosphodiesterase
BEN76_14120	COG0477	Major facilitator Superfamily
BEN76_14125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEN76_14145	COG1253	flavin adenine dinucleotide binding
BEN76_14155	COG2860	membrane
BEN76_14160	COG0477	Major facilitator Superfamily
BEN76_14170	COG0318	PFAM AMP-dependent synthetase and ligase
BEN76_14185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BEN76_14245	COG2217	Heavy metal translocating P-type atpase
BEN76_14250	COG2205	protein histidine kinase activity
BEN76_14265	COG2132	Multicopper oxidase
BEN76_14290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEN76_14335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BEN76_14380	COG0347	Belongs to the P(II) protein family
BEN76_14385	COG0004	ammonium transporteR
BEN76_14395	COG2801	Transposase and inactivated derivatives
BEN76_14400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BEN76_14405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEN76_14405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEN76_14430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BEN76_14440	COG0795	lipopolysaccharide-transporting ATPase activity
BEN76_14445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BEN76_14450	COG0793	Belongs to the peptidase S41A family
BEN76_14460	COG5002	protein histidine kinase activity
BEN76_14475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BEN76_14485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BEN76_14490	COG4974	Belongs to the 'phage' integrase family
BEN76_14510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BEN76_14515	COG0772	Belongs to the SEDS family
BEN76_14520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEN76_14525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BEN76_14535	COG0494	nUDIX hydrolase
BEN76_14540	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BEN76_14545	COG1538	Outer membrane efflux protein
BEN76_14560	COG0165	Argininosuccinate lyase
BEN76_14575	COG0181	hydroxymethylbilane synthase activity
BEN76_14595	COG0824	Thioesterase
BEN76_14625	COG0546	phosphoglycolate phosphatase activity
BEN76_14655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BEN76_14665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BEN76_14675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BEN76_14680	COG0081	regulation of translation
BEN76_14695	COG0085	RNA polymerase activity
BEN76_14700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BEN76_14720	COG2056	Na+-H+ antiporter family
BEN76_14735	COG0326	Molecular chaperone. Has ATPase activity
BEN76_14755	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BEN76_14770	COG0183	Belongs to the thiolase family
BEN76_14775	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEN76_14775	COG1024	Enoyl-CoA hydratase
BEN76_14790	COG0322	excinuclease ABC activity
BEN76_14800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BEN76_14805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BEN76_14805	COG2169	Transcriptional regulator
BEN76_14835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BEN76_14840	COG1678	Uncharacterized ACR, COG1678
BEN76_14845	COG0497	DNA recombination
BEN76_14855	COG3123	guanosine phosphorylase activity
BEN76_14860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEN76_14865	COG0697	spore germination
BEN76_14870	COG0237	dephospho-CoA kinase activity
BEN76_14890	COG0149	triose-phosphate isomerase activity
BEN76_14915	COG0779	Required for maturation of 30S ribosomal subunits
BEN76_14920	COG0195	Participates in both transcription termination and antitermination
BEN76_14925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BEN76_14930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BEN76_14940	COG2212	antiporter activity
BEN76_14950	COG0651	ATP synthesis coupled electron transport
BEN76_14955	COG1006	Multisubunit Na H antiporter MnhC subunit
BEN76_14960	COG2111	Na H antiporter
BEN76_14960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEN76_14975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BEN76_14980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BEN76_15010	COG3121	Chaperone
BEN76_15040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BEN76_15045	COG1074	ATP-dependent DNA helicase activity
BEN76_15050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEN76_15065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BEN76_15070	COG1185	polyribonucleotide nucleotidyltransferase activity
BEN76_15075	COG4773	Receptor
BEN76_15085	COG0598	Magnesium transport protein CorA
BEN76_15090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BEN76_15105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BEN76_15115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BEN76_15140	COG4535	Mg2 and Co2 transporter CorC
BEN76_15145	COG0425	Belongs to the sulfur carrier protein TusA family
BEN76_15150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BEN76_15155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BEN76_15165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BEN76_15165	COG0493	'glutamate synthase
BEN76_15175	COG1522	sequence-specific DNA binding
BEN76_15180	COG0626	cystathionine gamma-synthase activity
BEN76_15190	COG0254	rRNA binding
BEN76_15195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BEN76_15210	COG0534	Mate efflux family protein
BEN76_15220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BEN76_15225	COG0450	alkyl hydroperoxide reductase
BEN76_15245	COG1530	ribonuclease E activity
BEN76_15255	COG0564	pseudouridine synthase activity
BEN76_15260	COG0546	phosphoglycolate phosphatase activity
BEN76_15270	COG0625	glutathione transferase activity
BEN76_15280	COG0583	DNA-binding transcription factor activity
BEN76_15290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BEN76_15300	COG0494	nUDIX hydrolase
BEN76_15310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BEN76_15315	COG0583	DNA-binding transcription factor activity
BEN76_15325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BEN76_15330	COG0066	3-isopropylmalate dehydratase activity
BEN76_15340	COG0473	3-isopropylmalate dehydrogenase activity
BEN76_15350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BEN76_15360	COG0101	tRNA pseudouridine synthase activity
BEN76_15375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BEN76_15385	COG1301	dicarboxylic acid transport
BEN76_15390	COG0438	transferase activity, transferring glycosyl groups
BEN76_15395	COG1560	Kdo2-lipid A biosynthetic process
BEN76_15425	COG0210	DNA helicase
BEN76_15430	COG0724	RNA recognition motif
BEN76_15450	COG4651	solute:proton antiporter activity
BEN76_15450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BEN76_15455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BEN76_15460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BEN76_15475	COG0788	formyltetrahydrofolate deformylase activity
BEN76_15515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BEN76_15530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BEN76_15555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BEN76_15570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BEN76_15580	COG2813	Specifically methylates the guanine in position
BEN76_15580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN76_15585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BEN76_15590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BEN76_15595	COG3128	pkhd-type hydroxylase
BEN76_15600	COG4774	siderophore transport
BEN76_15605	COG0544	peptidyl-prolyl cis-trans isomerase activity
BEN76_15610	COG0740	serine-type endopeptidase activity
BEN76_15615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BEN76_15625	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BEN76_15625	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BEN76_15635	COG0857	belongs to the CobB CobQ family
BEN76_15635	COG0280	phosphate acetyltransferase
BEN76_15640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BEN76_15650	COG0800	Aldolase
BEN76_15655	COG2610	gluconate transmembrane transporter activity
BEN76_15660	COG3265	gluconokinase activity
BEN76_15670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BEN76_15690	COG0793	Belongs to the peptidase S41A family
BEN76_15705	COG2975	iron-sulfur cluster assembly
BEN76_15710	COG0105	UTP biosynthetic process
BEN76_15715	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BEN76_15720	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BEN76_15725	COG1426	Protein conserved in bacteria
BEN76_15730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BEN76_15735	COG0124	histidyl-tRNA synthetase
BEN76_15765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BEN76_15775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BEN76_15830	COG1028	Short-chain dehydrogenase reductase Sdr
BEN76_15855	COG1862	Preprotein translocase
BEN76_15860	COG0343	queuine tRNA-ribosyltransferase activity
BEN76_15865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BEN76_15875	COG0477	Major facilitator Superfamily
BEN76_15880	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_15890	COG5002	protein histidine kinase activity
BEN76_15895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BEN76_15915	COG0726	polysaccharide deacetylase
BEN76_15920	COG0463	Glycosyl transferase, family 2
BEN76_15925	COG0438	transferase activity, transferring glycosyl groups
BEN76_15965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BEN76_16010	COG3223	Belongs to the PsiE family
BEN76_16015	COG1960	acyl-CoA dehydrogenase activity
BEN76_16020	COG1960	acyl-CoA dehydrogenase activity
BEN76_16030	COG2205	protein histidine kinase activity
BEN76_16035	COG0745	RESPONSE REGULATOR receiver
BEN76_16040	COG2315	Protein conserved in bacteria
BEN76_16075	COG2096	Adenosyltransferase
BEN76_16080	COG4206	TonB-dependent receptor
BEN76_16090	COG0133	tryptophan synthase activity
BEN76_16115	COG0159	tryptophan synthase activity
BEN76_16120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BEN76_16125	COG0285	dihydrofolate synthase activity
BEN76_16135	COG1301	dicarboxylic acid transport
BEN76_16145	COG0450	alkyl hydroperoxide reductase
BEN76_16150	COG0653	protein targeting
BEN76_16160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BEN76_16165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BEN76_16190	COG2885	chlorophyll binding
BEN76_16195	COG2199	diguanylate cyclase activity
BEN76_16285	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BEN76_16285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEN76_16295	COG4680	protein conserved in bacteria
BEN76_16330	COG1570	exodeoxyribonuclease VII activity
BEN76_16360	COG0582	viral genome integration into host DNA
BEN76_16430	COG1024	Enoyl-CoA hydratase
BEN76_16435	COG0183	Belongs to the thiolase family
BEN76_16445	COG1024	Enoyl-CoA hydratase
BEN76_16450	COG0318	PFAM AMP-dependent synthetase and ligase
BEN76_16455	COG0183	Belongs to the thiolase family
BEN76_16460	COG1960	acyl-CoA dehydrogenase activity
BEN76_16485	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_16540	COG3724	N-succinylarginine dihydrolase activity
BEN76_16545	COG1012	belongs to the aldehyde dehydrogenase family
BEN76_16555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BEN76_16560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEN76_16565	COG1113	amino acid transport
BEN76_16575	COG1522	sequence-specific DNA binding
BEN76_16630	COG1475	DNA binding
BEN76_16680	COG1192	Involved in chromosome partitioning
BEN76_16770	COG1132	(ABC) transporter
BEN76_16905	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BEN76_17015	COG1280	lysine exporter protein (LysE YggA)
BEN76_17020	COG1309	transcriptional regulator
BEN76_17060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BEN76_17105	COG0531	amino acid
BEN76_17110	COG2040	homocysteine
BEN76_17150	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BEN76_17200	COG1335	isochorismatase