locus-tag	class	description
E5Y90_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
E5Y90_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5Y90_00025	ENOG4105E2A	Dehydrogenase
E5Y90_00030	ENOG4105C5H	ABC transporter
E5Y90_00035	ENOG4108821	RND type efflux pump
E5Y90_00040	ENOG4108821	RND type efflux pump
E5Y90_00045	ENOG4108821	RND type efflux pump
E5Y90_00050	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E5Y90_00090	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
E5Y90_00125	ENOG4105D2S	major facilitator superfamily
E5Y90_00130	ENOG4105D2S	major facilitator superfamily
E5Y90_00140	ENOG4107SNB	ankyrin repeat protein YahD
E5Y90_00145	ENOG4107RKG	DJ-1/PfpI family
E5Y90_00160	ENOG4105C8J	)-transporter
E5Y90_00170	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
E5Y90_00180	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E5Y90_00195	ENOG4105C01	Dihydroxy-acid dehydratase
E5Y90_00220	ENOG4105C2W	permease
E5Y90_00235	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5Y90_00285	ENOG4106BRA	Membrane
E5Y90_00300	ENOG4105D9M	gamma-glutamylcysteine synthetase
E5Y90_00305	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
E5Y90_00315	ENOG4105IPS	esterase
E5Y90_00320	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5Y90_00355	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E5Y90_00360	ENOG4105BZU	Histidine kinase
E5Y90_00365	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E5Y90_00380	ENOG4105KUZ	arsenate reductase
E5Y90_00385	ENOG4105CGK	Exodeoxyribonuclease III
E5Y90_00400	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E5Y90_00410	ENOG4108ZAI	phosphatidylglycerophosphatase a
E5Y90_00415	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E5Y90_00430	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E5Y90_00445	ENOG4105D05	Receptor
E5Y90_00495	ENOG4106FTQ	Taurine ABC transporter, periplasmic
E5Y90_00500	ENOG4108IY8	ABC, transporter
E5Y90_00505	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
E5Y90_00515	ENOG4105DAA	L-lactate
E5Y90_00520	ENOG41073TP	transcriptional regulator
E5Y90_00530	ENOG4105CXG	d-lactate dehydrogenase
E5Y90_00580	ENOG4105C0D	helicase
E5Y90_00670	ENOG4107QKA	exodeoxyribonuclease V beta
E5Y90_00685	ENOG4105E5H	Transposase
E5Y90_00695	ENOG4105IYK	transposase
E5Y90_00715	ENOG4105EKQ	RNA-directed DNA polymerase
E5Y90_00730	ENOG41090BB	DNA mismatch endonuclease (vsr)
E5Y90_00735	ENOG4105DVF	Cytosine-specific methyltransferase
E5Y90_00775	ENOG4105ZTP	Protein of unknown function (DUF1376)
E5Y90_00820	ENOG4107QJE	Chromosome Partitioning Protein
E5Y90_00835	ENOG4105DQR	SNARE associated Golgi
E5Y90_00840	ENOG4105H4F	exported protein
E5Y90_00845	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5Y90_00850	ENOG4105BZU	Histidine kinase
E5Y90_00855	ENOG4105EUB	pirin domain protein
E5Y90_00860	ENOG4108RXX	maleylacetoacetate isomerase
E5Y90_00865	ENOG4105BZU	Histidine kinase
E5Y90_00870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5Y90_00885	ENOG4107QJQ	Mate efflux family protein
E5Y90_00935	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E5Y90_00970	ENOG4105CUV	Homoserine Kinase
E5Y90_01005	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E5Y90_01060	ENOG4105CHU	acetyl-coa acetyltransferase
E5Y90_01080	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
E5Y90_01095	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
E5Y90_01115	ENOG4108HRK	Histidine kinase
E5Y90_01120	ENOG4108NEV	two component transcriptional regulator, LytTR family
E5Y90_01125	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E5Y90_01150	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
E5Y90_01165	ENOG4105GVR	general secretion pathway protein D
E5Y90_01175	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5Y90_01215	ENOG4105PM1	preprotein translocase subunit SecE
E5Y90_01220	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
E5Y90_01225	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E5Y90_01230	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E5Y90_01235	ENOG4108VZM	50s ribosomal protein L10
E5Y90_01245	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E5Y90_01275	ENOG4105D3Y	Na H antiporter
E5Y90_01290	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E5Y90_01315	ENOG4107ZXU	DSBA oxidoreductase
E5Y90_01320	ENOG4105CYC	Transferase
E5Y90_01325	ENOG4105E0F	Histidine kinase
E5Y90_01350	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
E5Y90_01360	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E5Y90_01370	ENOG4105CSR	polyphosphate kinase 2
E5Y90_01380	ENOG4105DSY	exodeoxyribonuclease V, gamma
E5Y90_01385	ENOG4107QKA	exodeoxyribonuclease V beta
E5Y90_01390	ENOG4107QYX	exodeoxyribonuclease v alpha
E5Y90_01400	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E5Y90_01405	ENOG4107QUT	magnesium and cobalt transport protein CorA
E5Y90_01410	ENOG4105Z2P	Protein of unknown function (DUF465)
E5Y90_01415	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
E5Y90_01425	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
E5Y90_01435	ENOG4105C25	Primosomal protein n'
E5Y90_01440	ENOG4105D7Q	type ii secretion system
E5Y90_01445	ENOG4108VAU	general secretion pathway protein G
E5Y90_01460	ENOG4108JU5	Magnesium and cobalt efflux protein
E5Y90_01465	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
E5Y90_01470	ENOG4105CS6	Rhs element vgr protein
E5Y90_01485	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E5Y90_01495	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E5Y90_01510	ENOG4105C5X	domain protein
E5Y90_01520	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
E5Y90_01530	ENOG4105BZ8	glutamate synthase
E5Y90_01540	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5Y90_01555	ENOG4105C5I	Dehydrogenase
E5Y90_01575	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
E5Y90_01590	ENOG4105C8P	)-transporter
E5Y90_01600	ENOG41067S9	phage shock protein C, PspC
E5Y90_01625	ENOG4105J5T	Amp-dependent synthetase and ligase
E5Y90_01630	ENOG4105C03	ribonuclease
E5Y90_01640	ENOG4105EI2	Pseudouridine synthase
E5Y90_01645	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5Y90_01650	ENOG4105IKQ	hydratase
E5Y90_01655	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
E5Y90_01660	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
E5Y90_01665	ENOG4105EPF	Outer membrane porin
E5Y90_01675	ENOG4105IYK	transposase
E5Y90_01685	ENOG4105E5H	Transposase
E5Y90_01690	ENOG4108W5M	transcriptional regulator
E5Y90_01695	ENOG4105FUY	alpha subunit
E5Y90_01710	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
E5Y90_01715	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
E5Y90_01720	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
E5Y90_01740	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
E5Y90_01745	ENOG4105CH6	catalase
E5Y90_01750	ENOG4105CSU	acyl-Coa dehydrogenase
E5Y90_01760	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
E5Y90_01785	ENOG4105DUM	transcriptional regulator, lysR family
E5Y90_01795	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E5Y90_01810	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E5Y90_01860	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E5Y90_01865	ENOG4105C5H	ABC transporter
E5Y90_01870	ENOG4105VRX	Protein slyX homolog
E5Y90_01885	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
E5Y90_01900	ENOG4105BZW	Glycerate kinase
E5Y90_01910	ENOG4105VFU	Rna-binding protein
E5Y90_01925	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E5Y90_01940	ENOG4107RGH	Aldehyde dehydrogenase
E5Y90_01945	ENOG41062JF	Transcriptional regulator
E5Y90_01950	ENOG4105CIY	formyltetrahydrofolate deformylase
E5Y90_01990	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E5Y90_02030	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
E5Y90_02045	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E5Y90_02060	ENOG4105DWV	Homoserine O-trans-acetylase
E5Y90_02065	ENOG4105DWV	Homoserine O-trans-acetylase
E5Y90_02070	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E5Y90_02080	ENOG4108ESX	Receptor
E5Y90_02085	ENOG4105D05	Receptor
E5Y90_02095	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E5Y90_02110	ENOG4107GFK	fumarate
E5Y90_02120	ENOG4108FUF	Transcriptional regulator, IclR family
E5Y90_02125	ENOG4105C26	Dehydrogenase
E5Y90_02130	ENOG4105C0A	alcohol dehydrogenase
E5Y90_02135	ENOG4105CY2	Citrate transporter
E5Y90_02140	ENOG4108DNC	Involved in acetate metabolism (By similarity)
E5Y90_02145	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E5Y90_02170	ENOG4105CN1	protease
E5Y90_02195	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5Y90_02200	ENOG4105W8H	transhydrogenase (subunit alpha
E5Y90_02205	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
E5Y90_02210	ENOG4105EMK	carboxylate amino acid amine transporter
E5Y90_02220	ENOG4105VKU	nucleicacid-binding protein
E5Y90_02225	ENOG4105DGW	oligopeptidase A
E5Y90_02235	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E5Y90_02270	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E5Y90_02275	ENOG4107S2Z	UPF0761 membrane protein
E5Y90_02280	ENOG4105CS1	NAD(P)H quinone oxidoreductase
E5Y90_02325	ENOG4105C9A	Phoh family
E5Y90_02335	ENOG4105E4C	Lytic transglycosylase catalytic
E5Y90_02375	ENOG4105D6S	protein involved in catabolism of external DNA
E5Y90_02380	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E5Y90_02445	ENOG4105NAU	thioesterase Superfamily protein
E5Y90_02475	ENOG4105K9H	YciI-like protein
E5Y90_02485	ENOG4105DB7	PHP domain protein
E5Y90_02490	ENOG4105FFC	UPF0187 protein
E5Y90_02495	ENOG4105W5Q	DNA repair protein (RadC
E5Y90_02500	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
E5Y90_02510	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5Y90_02515	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E5Y90_02525	ENOG4108ZJ4	polysaccharide deacetylase
E5Y90_02530	ENOG4105F8V	Hydrolase, tatD family
E5Y90_02535	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E5Y90_02545	ENOG4105VW4	glutaredoxin 3
E5Y90_02555	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E5Y90_02560	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
E5Y90_02565	ENOG4105CUZ	uba thif-type nad fad binding protein
E5Y90_02575	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5Y90_02580	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E5Y90_02585	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
E5Y90_02590	ENOG4105IYK	transposase
E5Y90_02600	ENOG4105E5H	Transposase
E5Y90_02630	ENOG4105C7K	acetolactate synthase
E5Y90_02635	ENOG4108ZP8	Acetolactate synthase small subunit
E5Y90_02675	ENOG4105WVQ	Fe-S assembly protein IscX
E5Y90_02690	ENOG4105CFV	Tetratricopeptide repeat protein
E5Y90_02695	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
E5Y90_02705	ENOG4105CUT	histidyl-tRNA synthetase
E5Y90_02715	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
E5Y90_02740	ENOG4105DXN	mazG family
E5Y90_02745	ENOG4105KQC	Competence protein
E5Y90_02750	ENOG4105DJ0	Poly(A) Polymerase
E5Y90_02755	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E5Y90_02770	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E5Y90_02775	ENOG41080Z8	PHOSPHOCARRIER protein
E5Y90_02780	ENOG4105N42	UPF0307 protein
E5Y90_02785	ENOG4105BZU	Histidine kinase
E5Y90_02790	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
E5Y90_02795	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E5Y90_02805	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5Y90_02825	ENOG4107J0A	lipopolysaccharide biosynthetic process
E5Y90_02830	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E5Y90_02835	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E5Y90_02845	ENOG4108UT6	Transferase hexapeptide repeat containing protein
E5Y90_02855	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5Y90_02860	ENOG41090RK	glycosyl transferase
E5Y90_02885	ENOG4105C9M	aspartyl-trna synthetase
E5Y90_02895	ENOG4105UGU	tonB-dependent Receptor
E5Y90_02920	ENOG4105CSU	acyl-Coa dehydrogenase
E5Y90_02925	ENOG4105CSU	acyl-Coa dehydrogenase
E5Y90_02935	ENOG4105EB3	Histidine kinase
E5Y90_02940	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
E5Y90_02950	ENOG4105CNG	UPF0061 protein
E5Y90_02965	ENOG4108WBT	adenosyltransferase
E5Y90_02970	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E5Y90_02985	ENOG4105C2M	dna polymerase I
E5Y90_03005	ENOG4107QHF	type ii secretion system protein e
E5Y90_03010	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E5Y90_03030	ENOG410903C	(LipO)protein
E5Y90_03080	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E5Y90_03090	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E5Y90_03100	ENOG4105CRQ	synthase (Component I)
E5Y90_03140	ENOG4105P8F	nudix hydrolase
E5Y90_03150	ENOG41072GX	Peptidase M22 Glycoprotease
E5Y90_03155	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E5Y90_03170	ENOG4105C4W	S-formylglutathione hydrolase
E5Y90_03185	ENOG4105DJV	ribulose-phosphate 3-epimerase
E5Y90_03220	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E5Y90_03240	ENOG4108EKN	Biotin protein ligase C terminal domain
E5Y90_03245	ENOG4105HF0	Membrane
E5Y90_03255	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E5Y90_03265	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E5Y90_03275	ENOG4108UWD	Iron-storage protein
E5Y90_03310	ENOG4105FE9	pseudouridine synthase
E5Y90_03315	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E5Y90_03320	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E5Y90_03330	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E5Y90_03335	ENOG4108BPE	-transporting atpase
E5Y90_03340	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
E5Y90_03350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E5Y90_03355	ENOG4105CHR	reductase
E5Y90_03360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E5Y90_03365	ENOG4109066	lysm domain bon superfamily protein
E5Y90_03370	ENOG4105EW9	transcriptional regulator AsnC family
E5Y90_03385	ENOG4105M4H	endoribonuclease L-psp
E5Y90_03395	ENOG4108YXA	Membrane
E5Y90_03410	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E5Y90_03435	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
E5Y90_03450	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E5Y90_03455	ENOG4105C3M	thioredoxin reductase
E5Y90_03460	ENOG4105CNU	cell division protein FtsK
E5Y90_03475	ENOG4107QMS	site-determining protein
E5Y90_03480	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
E5Y90_03490	ENOG4106HNH	Acyl-transferase
E5Y90_03495	ENOG4108ZG0	Ompa motb domain protein
E5Y90_03500	ENOG4105C4R	Atp-dependent dna helicase
E5Y90_03505	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E5Y90_03525	ENOG4107QKV	phosphomannomutase
E5Y90_03530	ENOG4105CAS	nag kinase
E5Y90_03535	ENOG4105E7A	Glutamine amidotransferase
E5Y90_03565	ENOG41090R7	Ferric uptake
E5Y90_03570	ENOG4105CZX	twitching motility protein
E5Y90_03575	ENOG4105CZX	twitching motility protein
E5Y90_03580	ENOG4105DFA	alanine racemase domain protein
E5Y90_03590	ENOG4105EYH	Exonuclease
E5Y90_03595	ENOG4107RH8	nuclease SbcCD subunit D
E5Y90_03605	ENOG4105ECP	epimerase
E5Y90_03610	ENOG4108DN8	FAD dependent oxidoreductase
E5Y90_03615	ENOG4105D52	delta-aminolevulinic acid dehydratase
E5Y90_03620	ENOG4108VUY	thioesterase Superfamily protein
E5Y90_03625	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E5Y90_03665	ENOG4105G6Z	alkaline phosphatase
E5Y90_03670	ENOG4105G6Z	alkaline phosphatase
E5Y90_03680	ENOG4108ZX5	transcriptional regulator
E5Y90_03700	ENOG4105E02	MotA TolQ exbB proton channel
E5Y90_03705	ENOG4105M8F	Biopolymer transport protein exbD tolR
E5Y90_03770	ENOG4105WPN	DNA integration recombination invertion protein
E5Y90_03775	ENOG4105CSH	Transporter
E5Y90_03785	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E5Y90_03790	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E5Y90_03795	ENOG4105HF0	Membrane
E5Y90_03800	ENOG4105DZ2	Transcriptional regulator
E5Y90_03815	ENOG4105CF7	AraC family transcriptional regulator
E5Y90_03820	ENOG4105D2S	major facilitator superfamily
E5Y90_03835	ENOG4105F57	Anthranilate dioxygenase reductase
E5Y90_03840	ENOG4108YS2	small subunit
E5Y90_03845	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
E5Y90_03875	ENOG4105CNM	Receptor
E5Y90_03890	ENOG4105EJC	lysr family transcriptional regulator
E5Y90_03895	ENOG4105C94	Transporter
E5Y90_03900	ENOG4105F2M	alpha beta hydrolase fold-3 domain protein
E5Y90_03905	ENOG4105DVW	rieske (2Fe-2S)
E5Y90_03915	ENOG4105E3J	oxidoreductase
E5Y90_03925	ENOG4107R1I	NAD-dependent malic enzyme
E5Y90_03945	ENOG4105EUV	Phenol 2-monooxygenase
E5Y90_03965	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
E5Y90_03980	ENOG41080HT	Transcriptional regulator, arsr family
E5Y90_04030	ENOG4106UW1	Major Facilitator superfamily
E5Y90_04035	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E5Y90_04040	ENOG4108K4C	ec 3.1.3.12
E5Y90_04095	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E5Y90_04105	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E5Y90_04115	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
E5Y90_04120	ENOG4105VQ7	Rod shape-determining protein MreD
E5Y90_04125	ENOG4108Z03	MAF-like protein
E5Y90_04130	ENOG4105C03	ribonuclease
E5Y90_04135	ENOG4105D8T	Acyltransferase
E5Y90_04145	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
E5Y90_04165	ENOG4105C85	amino acid
E5Y90_04170	ENOG4107R11	Transcriptional regulator
E5Y90_04175	ENOG4108IJ6	ABC transporter
E5Y90_04180	ENOG4105ECW	sulfate abc transporter
E5Y90_04185	ENOG4108I5D	sulfate abc transporter
E5Y90_04195	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E5Y90_04205	ENOG4105HHA	aminodeoxychorismate lyase
E5Y90_04220	ENOG4108IYU	L-aspartate oxidase
E5Y90_04225	ENOG4105C0H	protease
E5Y90_04240	ENOG4105C3F	Signal peptidase i
E5Y90_04250	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E5Y90_04255	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E5Y90_04265	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
E5Y90_04270	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E5Y90_04275	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
E5Y90_04305	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E5Y90_04310	ENOG4105CE9	30S ribosomal protein S2
E5Y90_04330	ENOG4105CVE	Lytic murein transglycosylase
E5Y90_04345	ENOG4105E3A	(ABC) transporter
E5Y90_04350	ENOG4105DA5	(ABC) transporter
E5Y90_04365	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
E5Y90_04375	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E5Y90_04420	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
E5Y90_04425	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
E5Y90_04435	ENOG4105E33	succinate dehydrogenase
E5Y90_04440	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E5Y90_04445	ENOG4105C7S	Dehydrogenase
E5Y90_04450	ENOG4107QN2	dihydrolipoyl dehydrogenase
E5Y90_04460	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E5Y90_04475	ENOG4107BJW	polysaccharide deacetylase
E5Y90_04495	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
E5Y90_04505	ENOG4105DHQ	Histidine kinase
E5Y90_04515	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E5Y90_04525	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
E5Y90_04550	ENOG4105DZ2	Transcriptional regulator
E5Y90_04620	ENOG4108JU3	Alkyl hydroperoxide reductase
E5Y90_04625	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E5Y90_04630	ENOG4105CFP	Peptidase U32
E5Y90_04635	ENOG4108Z6Z	Transcriptional regulator
E5Y90_04645	ENOG4105DP0	ferredoxin-NADP reductase
E5Y90_04650	ENOG4108R96	Methyltransferase, YaeB family
E5Y90_04660	ENOG4107QHF	type ii secretion system protein e
E5Y90_04670	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
E5Y90_04675	ENOG4105DHQ	Histidine kinase
E5Y90_04685	ENOG4105M6F	mutator MutT protein
E5Y90_04695	ENOG4105BZ4	penicillin-binding protein
E5Y90_04700	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E5Y90_04705	ENOG4105VUT	cytoplasmic protein
E5Y90_04715	ENOG4105CK2	sodium dicarboxylate symporter
E5Y90_04720	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_04725	ENOG4107R7Y	intracellular protease Pfpi family
E5Y90_04735	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E5Y90_04740	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E5Y90_04765	ENOG4105C7N	Xanthine uracil vitamin C permease
E5Y90_04770	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
E5Y90_04790	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E5Y90_04800	ENOG4105CFH	Aspartokinase
E5Y90_04810	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E5Y90_04825	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E5Y90_04840	ENOG4108YZY	peptidylprolyl cis-trans isomerase
E5Y90_04850	ENOG4105DZ1	carboxypeptidase
E5Y90_04865	ENOG4108UHE	carbonic anhydrase
E5Y90_04870	ENOG4107ZQV	short-chain dehydrogenase reductase
E5Y90_04880	ENOG4105HSS	phospholipase C
E5Y90_04890	ENOG4105IYK	transposase
E5Y90_04900	ENOG4105E5H	Transposase
E5Y90_04910	ENOG4108R99	pseudouridine synthase
E5Y90_04920	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
E5Y90_04945	ENOG4105CHM	Aminotransferase
E5Y90_04950	ENOG4105E0X	reductase
E5Y90_04955	ENOG4108V06	Glutathione peroxidase
E5Y90_04960	ENOG4105CHM	Aminotransferase
E5Y90_04965	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
E5Y90_04975	ENOG4105ZED	uncharacterized protein ygaH
E5Y90_04980	ENOG4108UMN	azlc family
E5Y90_05000	ENOG4105NX3	Membrane
E5Y90_05015	ENOG4105BZU	Histidine kinase
E5Y90_05030	ENOG4105EUJ	GTP cyclohydrolase i
E5Y90_05045	ENOG4107QYG	anthranilate phosphoribosyltransferase
E5Y90_05050	ENOG4105DDQ	anthranilate synthase
E5Y90_05070	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E5Y90_05115	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5Y90_05120	ENOG4107QNR	UPF0135 protein
E5Y90_05125	ENOG4105C0H	protease
E5Y90_05155	ENOG4107QPN	acyl-Coa dehydrogenase
E5Y90_05160	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5Y90_05165	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
E5Y90_05195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E5Y90_05205	ENOG4105DTR	rard protein
E5Y90_05235	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E5Y90_05240	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E5Y90_05255	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
E5Y90_05270	ENOG4108JU3	Alkyl hydroperoxide reductase
E5Y90_05285	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E5Y90_05290	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
E5Y90_05295	ENOG4105EHM	Aminoglycoside phosphotransferase
E5Y90_05300	ENOG4108S0S	Nucleotidyl transferase
E5Y90_05310	ENOG4107QJE	Chromosome Partitioning Protein
E5Y90_05315	ENOG4105FA0	parb-like partition protein
E5Y90_05330	ENOG4105BZ1	(ABC) transporter
E5Y90_05335	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E5Y90_05345	ENOG4107QRG	dna polymerase iii
E5Y90_05355	ENOG4105F8V	Hydrolase, tatD family
E5Y90_05360	ENOG4105R8C	Transcriptional regulator
E5Y90_05380	ENOG4108RTD	type II secretion system protein K
E5Y90_05390	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E5Y90_05400	ENOG4108Z6B	deaminase
E5Y90_05415	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E5Y90_05420	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
E5Y90_05435	ENOG4105DWU	Membrane
E5Y90_05440	ENOG4107RN6	Monooxygenase
E5Y90_05450	ENOG4105D6Z	AFG1 family ATPase
E5Y90_05455	ENOG4107QP3	malate synthase g
E5Y90_05475	ENOG4105EE5	Membrane protein terC
E5Y90_05490	ENOG4105CD8	aminopeptidase N
E5Y90_05500	ENOG41081QV	Universal stress protein
E5Y90_05515	ENOG4105DKK	Benzoate
E5Y90_05520	ENOG4108NIW	Leucine export protein LeuE
E5Y90_05525	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E5Y90_05530	ENOG4105HEI	LysR family (Transcriptional regulator
E5Y90_05545	ENOG4105CHU	acetyl-coa acetyltransferase
E5Y90_05550	ENOG4105CHR	reductase
E5Y90_05565	ENOG4105IYK	transposase
E5Y90_05575	ENOG4105E5H	Transposase
E5Y90_05580	ENOG4105CAU	Arsenical resistance protein, ArsH
E5Y90_05585	ENOG4105D6J	arsenicaL-resistance protein
E5Y90_05590	ENOG41082YX	Transcriptional regulator, arsr family
E5Y90_05610	ENOG4105D3G	Pseudouridine synthase
E5Y90_05615	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
E5Y90_05630	ENOG4105EJ2	Transcriptional regulator
E5Y90_05660	ENOG4107QIJ	Aconitate hydratase 2
E5Y90_05675	ENOG4105EW9	transcriptional regulator AsnC family
E5Y90_05695	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
E5Y90_05700	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
E5Y90_05705	ENOG4105CC0	LysR family Transcriptional regulator
E5Y90_05710	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E5Y90_05725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5Y90_05755	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E5Y90_05760	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
E5Y90_05770	ENOG4105CNI	cell division protein FtsW
E5Y90_05785	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5Y90_05790	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5Y90_05805	ENOG4107QNJ	CoA-transferase subunit B
E5Y90_05815	ENOG4108M0I	Transcriptional regulator
E5Y90_05820	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E5Y90_05860	ENOG4105C0B	DNA polymerase III (alpha subunit)
E5Y90_05865	ENOG4108UMI	ABC transporter, permease
E5Y90_05870	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
E5Y90_05880	ENOG4105C12	Phosphoribosylglycinamide synthetase
E5Y90_05885	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E5Y90_05890	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
E5Y90_05925	ENOG4108SC4	)-transporter
E5Y90_05935	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5Y90_05940	ENOG4105CUX	Signal transduction histidine kinase
E5Y90_05960	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E5Y90_05965	ENOG4105KNE	Phosphatidate cytidylyltransferase
E5Y90_05975	ENOG4105DZP	Membrane-associated zinc metalloprotease
E5Y90_05980	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5Y90_05990	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5Y90_05995	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E5Y90_06000	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5Y90_06015	ENOG4105Y3E	Modulates RecA activity (By similarity)
E5Y90_06020	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E5Y90_06025	ENOG4105VEJ	Heat shock protein
E5Y90_06030	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
E5Y90_06035	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
E5Y90_06050	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
E5Y90_06055	ENOG4105K4T	epimerase
E5Y90_06060	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E5Y90_06070	ENOG4105EZE	Cupin 4 family protein
E5Y90_06080	ENOG4108UHJ	MAF-like protein
E5Y90_06090	ENOG4105BZA	Phosphoglycerate kinase
E5Y90_06100	ENOG4105D2N	Aldolase
E5Y90_06105	ENOG4108TZV	Membrane
E5Y90_06115	ENOG4108RCM	Nitroreductase
E5Y90_06125	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
E5Y90_06135	ENOG4105CX6	glutaminyL-tRNA synthetase
E5Y90_06140	ENOG4105FFC	UPF0187 protein
E5Y90_06155	ENOG4108JJ7	ABC transporter
E5Y90_06165	ENOG4107QMP	dna polymerase iii subunits gamma and tau
E5Y90_06175	ENOG4105C0A	alcohol dehydrogenase
E5Y90_06180	ENOG4105KJF	protein tyrosine phosphatase
E5Y90_06200	ENOG4105CBC	glutamate synthase
E5Y90_06225	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E5Y90_06230	ENOG4105CDU	Replicative dna helicase
E5Y90_06255	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
E5Y90_06260	ENOG4105CCU	oxidase (Subunit III)
E5Y90_06265	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E5Y90_06270	ENOG4105E2S	oxidase) subunit II
E5Y90_06295	ENOG4105DEN	Luciferase family
E5Y90_06310	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E5Y90_06315	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E5Y90_06335	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_06355	ENOG4105D06	uba thif-type nad fad binding protein
E5Y90_06380	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
E5Y90_06385	ENOG4105CFU	surface antigen
E5Y90_06415	ENOG4107QS8	(LipO)protein
E5Y90_06465	ENOG4105NI8	Cytosine-specific methyltransferase
E5Y90_06705	ENOG4105NVB	glycoside hydrolase, family 19
E5Y90_06730	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E5Y90_06750	ENOG41066VF	YeeE YedE family protein
E5Y90_06765	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E5Y90_06775	ENOG4105F9F	transposase
E5Y90_06780	ENOG4105CV1	Transketolase (EC 2.2.1.1)
E5Y90_06790	ENOG4108YYC	ycei family
E5Y90_06800	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E5Y90_06805	ENOG4108SHQ	Glutathione S-transferase
E5Y90_06825	ENOG4105C2X	Arabinose 5-phosphate isomerase
E5Y90_06840	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
E5Y90_06845	ENOG4108IUZ	ABC transporter
E5Y90_06850	ENOG4105DFG	type I secretion outer membrane protein
E5Y90_06890	ENOG4108Z4U	Ferredoxin
E5Y90_06900	ENOG4105K59	histidine triad (HIT) protein
E5Y90_06910	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E5Y90_06920	ENOG4105C28	cystathionine
E5Y90_06930	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E5Y90_06960	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E5Y90_06965	ENOG41080XP	Cbs domain
E5Y90_07000	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E5Y90_07015	ENOG41068P6	UPF0319 protein
E5Y90_07050	ENOG4107SC1	transglycosylase
E5Y90_07055	ENOG4108MJ3	acetyltransferase
E5Y90_07060	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_07085	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
E5Y90_07125	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5Y90_07130	ENOG4107TSN	permease
E5Y90_07135	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E5Y90_07140	ENOG4105E7U	AraC family transcriptional regulator
E5Y90_07145	ENOG4105EEF	Alkane 1-monooxygenase
E5Y90_07150	ENOG4105CSU	acyl-Coa dehydrogenase
E5Y90_07170	ENOG4105C4M	(Ubiquinol oxidase) subunit I
E5Y90_07175	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
E5Y90_07185	ENOG4105KK6	nuclease
E5Y90_07190	ENOG41064T2	transcriptional regulator, lysR family
E5Y90_07195	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_07230	ENOG4107RZC	phospholipase d
E5Y90_07245	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
E5Y90_07250	ENOG4105CZM	Major Facilitator
E5Y90_07260	ENOG4108R6W	Transcriptional regulator, ARAC family
E5Y90_07265	ENOG4105BZ1	(ABC) transporter
E5Y90_07270	ENOG4105CUY	Mechanosensitive ion channel
E5Y90_07275	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
E5Y90_07295	ENOG41080HT	Transcriptional regulator, arsr family
E5Y90_07300	ENOG4105C6T	cysteine synthase
E5Y90_07320	ENOG41062JF	Transcriptional regulator
E5Y90_07325	ENOG4105CSU	acyl-Coa dehydrogenase
E5Y90_07330	ENOG4105CHU	acetyl-coa acetyltransferase
E5Y90_07335	ENOG4105CYC	Transferase
E5Y90_07350	ENOG4105F2Z	3-oxoadipate enol-lactonase
E5Y90_07355	ENOG4105CHU	acetyl-coa acetyltransferase
E5Y90_07360	ENOG4107QNJ	CoA-transferase subunit B
E5Y90_07365	ENOG4107QP7	CoA-transferase subunit A
E5Y90_07370	ENOG4105DKK	Benzoate
E5Y90_07375	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
E5Y90_07380	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
E5Y90_07385	ENOG4108UKV	benzoate 1,2-dioxygenase
E5Y90_07390	ENOG4105FUY	alpha subunit
E5Y90_07400	ENOG4105NN7	muconolactone delta-isomerase
E5Y90_07405	ENOG4105DTQ	mandelate racemase muconate lactonizing
E5Y90_07410	ENOG4108KB2	LysR family Transcriptional regulator
E5Y90_07415	ENOG4105D2S	major facilitator superfamily
E5Y90_07425	ENOG4105CEY	Amp-dependent synthetase and ligase
E5Y90_07430	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E5Y90_07440	ENOG4107YBY	Hydrolase
E5Y90_07445	ENOG4108PTX	LysR family Transcriptional regulator
E5Y90_07450	ENOG4105DDY	UPF0142 protein ycaO
E5Y90_07455	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
E5Y90_07470	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E5Y90_07485	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E5Y90_07490	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
E5Y90_07505	ENOG4107RR1	TRANSCRIPTIONal
E5Y90_07510	ENOG4105C0A	alcohol dehydrogenase
E5Y90_07520	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E5Y90_07525	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
E5Y90_07535	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E5Y90_07540	ENOG4107R0V	Pyruvate dehydrogenase
E5Y90_07545	ENOG4105CPP	Dehydrogenase, E1 component
E5Y90_07550	ENOG4105C7S	Dehydrogenase
E5Y90_07600	ENOG4105EV9	Alpha Beta Hydrolase
E5Y90_07625	ENOG4105CMR	udp-glucose 4-epimerase
E5Y90_07630	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
E5Y90_07655	ENOG4108Z66	YbaK ebsC protein
E5Y90_07665	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
E5Y90_07670	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E5Y90_07685	ENOG4105D8G	Major Facilitator superfamily
E5Y90_07730	ENOG410620I	Diguanylate cyclase
E5Y90_07750	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E5Y90_07780	ENOG4105BZN	citrate synthase
E5Y90_07785	ENOG4105CR4	methylisocitrate lyase
E5Y90_07810	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5Y90_07815	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
E5Y90_07825	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E5Y90_07840	ENOG4105E66	phosphoriboisomerase A
E5Y90_07845	ENOG4105C7B	Threonine dehydratase
E5Y90_07855	ENOG4105CZN	Potassium uptake protein
E5Y90_07860	ENOG4105HDD	phospholipase
E5Y90_07885	ENOG4105PV3	Inner membrane protein yqiJ
E5Y90_07905	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E5Y90_07910	ENOG4105K70	DNA-binding protein
E5Y90_07925	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
E5Y90_07935	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
E5Y90_07940	ENOG4108Z4V	iron-sulfur cluster assembly
E5Y90_07955	ENOG4108ZIT	Ferredoxin, 2FE-2S
E5Y90_07960	ENOG4105F8J	Adenylate Guanylate cyclase
E5Y90_07970	ENOG4108JA2	transcriptioN-repair coupling factor
E5Y90_07980	ENOG4108IJ0	Aspartate ammonia-lyase
E5Y90_08015	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E5Y90_08030	ENOG4105I7R	Adenylate cyclase
E5Y90_08060	ENOG4105JAB	phenazine biosynthesis protein, phzf family
E5Y90_08065	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E5Y90_08120	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
E5Y90_08135	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E5Y90_08140	ENOG4105CSH	Transporter
E5Y90_08145	ENOG4105EW9	transcriptional regulator AsnC family
E5Y90_08160	ENOG4105KTH	gatB Yqey
E5Y90_08170	ENOG4105ERG	peptidase m48, ste24p
E5Y90_08175	ENOG4105C5I	Dehydrogenase
E5Y90_08190	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E5Y90_08225	ENOG41069NU	Nitroreductase
E5Y90_08235	ENOG4105C1J	atp-dependent rna helicase
E5Y90_08250	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5Y90_08255	ENOG4105M08	Membrane
E5Y90_08280	ENOG4108K3A	Glutathione S-transferase
E5Y90_08285	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E5Y90_08305	ENOG4105CEY	Amp-dependent synthetase and ligase
E5Y90_08310	ENOG4108SGK	Tetr family transcriptional regulator
E5Y90_08315	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_08320	ENOG4107QX3	carboxylase
E5Y90_08325	ENOG4105E39	Enoyl-CoA hydratase
E5Y90_08345	ENOG4107QNJ	CoA-transferase subunit B
E5Y90_08350	ENOG4105CRW	Short chain fatty acid transporter
E5Y90_08360	ENOG4105CD3	dihydroorotase
E5Y90_08365	ENOG4105CXT	aspartate transcarbamylase
E5Y90_08375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E5Y90_08380	ENOG4105CPC	Aldo Keto reductase
E5Y90_08385	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
E5Y90_08390	ENOG4108UKZ	OsmC family
E5Y90_08395	ENOG4107S1Q	Phosphatase
E5Y90_08400	ENOG4105E9K	Isocitrate dehydrogenase
E5Y90_08410	ENOG4105F8C	transglutaminase domain-containing protein
E5Y90_08420	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E5Y90_08430	ENOG4105D22	carbon starvation protein
E5Y90_08435	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E5Y90_08440	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
E5Y90_08460	ENOG4105DHU	Bile acid
E5Y90_08475	ENOG4105DAN	ATP-dependent protease
E5Y90_08480	ENOG4105M2J	Glutaredoxin
E5Y90_08485	ENOG4105C8Y	Acetylornithine aminotransferase
E5Y90_08495	ENOG4105CR8	Transcriptional regulator
E5Y90_08500	ENOG4108K5P	(LipO)protein
E5Y90_08505	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E5Y90_08520	ENOG4105DZ1	carboxypeptidase
E5Y90_08525	ENOG4108Z0R	Transferase
E5Y90_08535	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
E5Y90_08545	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E5Y90_08550	ENOG4105K8N	protein family UPF0079, ATPase
E5Y90_08570	ENOG4105I08	Pseudouridine synthase
E5Y90_08575	ENOG4108VMM	UPF0756 membrane protein
E5Y90_08580	ENOG4105EYW	Ion transport protein
E5Y90_08585	ENOG4107QUV	Domain protein
E5Y90_08600	ENOG4105CQ7	ATP-dependent helicase
E5Y90_08605	ENOG4105D3R	alkyl hydroperoxide reductase
E5Y90_08630	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E5Y90_08635	ENOG41075W9	High frequency lysogenization protein HflD homolog
E5Y90_08640	ENOG4107QTF	adenylosuccinate lyase
E5Y90_08655	ENOG4105ERU	peptidase
E5Y90_08665	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
E5Y90_08675	ENOG4105C8U	phosphate abc transporter
E5Y90_08680	ENOG4105CVA	phosphate
E5Y90_08685	ENOG4105DY8	decarboxylase
E5Y90_08690	ENOG4108JPW	Aminotransferase
E5Y90_08765	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E5Y90_08775	ENOG4105KVH	Transcriptional regulator
E5Y90_08795	ENOG4105E5H	Transposase
E5Y90_08805	ENOG4105IYK	transposase
E5Y90_08815	ENOG4105E39	Enoyl-CoA hydratase
E5Y90_08820	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_08830	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E5Y90_08835	ENOG4105C26	Dehydrogenase
E5Y90_08840	ENOG4107YNJ	LysR family Transcriptional regulator
E5Y90_08850	ENOG41067CV	Integrase
E5Y90_08865	ENOG410626B	catechol 1,2-dioxygenase
E5Y90_08870	ENOG4108MR5	
E5Y90_08875	ENOG4108MZY	
E5Y90_08880	ENOG4108KB2	LysR family Transcriptional regulator
E5Y90_08885	ENOG4105DTQ	mandelate racemase muconate lactonizing
E5Y90_08890	ENOG4105NN7	muconolactone delta-isomerase
E5Y90_08895	ENOG4107QP7	CoA-transferase subunit A
E5Y90_08900	ENOG4107QNJ	CoA-transferase subunit B
E5Y90_08965	ENOG4105FUY	alpha subunit
E5Y90_08970	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E5Y90_08995	ENOG4105E5H	Transposase
E5Y90_09005	ENOG4105IYK	transposase
E5Y90_09065	ENOG4105C3G	gtp-binding protein
E5Y90_09070	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5Y90_09075	ENOG4105C2I	pirin domain protein
E5Y90_09085	ENOG4105M6W	Crispr-associated protein, Csy3 family
E5Y90_09095	ENOG4105ENG	CRISPR-associated protein, Csy1 family
E5Y90_09105	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
E5Y90_09115	ENOG4105F95	Monooxygenase
E5Y90_09130	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
E5Y90_09145	ENOG4107RCV	ABC transporter, permease
E5Y90_09150	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E5Y90_09155	ENOG4105C4Y	ABC transporter
E5Y90_09170	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5Y90_09190	ENOG4105EKE	dihydroorotase
E5Y90_09195	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
E5Y90_09205	ENOG4108IQI	permease
E5Y90_09215	ENOG4108IQI	permease
E5Y90_09250	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
E5Y90_09255	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
E5Y90_09260	ENOG4105E43	Extracellular solute-binding protein, family 5
E5Y90_09265	ENOG4105E9H	Lytic Murein transglycosylase
E5Y90_09270	ENOG4107RZZ	dna polymerase iii epsilon subunit
E5Y90_09280	ENOG4105E09	nadh pyrophosphatase
E5Y90_09290	ENOG4105W4M	Transport-associated protein
E5Y90_09300	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
E5Y90_09305	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
E5Y90_09315	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
E5Y90_09320	ENOG4105D0A	hydroxylase
E5Y90_09325	ENOG4105WG9	Conserved Protein
E5Y90_09330	ENOG4107RAQ	aminopeptidase
E5Y90_09355	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E5Y90_09365	ENOG4107VAM	peptidase, m28
E5Y90_09370	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E5Y90_09375	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E5Y90_09385	ENOG4105D82	Glutamate dehydrogenase
E5Y90_09390	ENOG4108R3D	Electron transport complex
E5Y90_09395	ENOG4105CSM	endonuclease III
E5Y90_09420	ENOG4105CJN	penicillin-binding protein
E5Y90_09425	ENOG4106H78	methyltransferase
E5Y90_09440	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E5Y90_09450	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
E5Y90_09490	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E5Y90_09505	ENOG4105C4K	Nad synthetase
E5Y90_09520	ENOG4107YZX	Universal stress protein
E5Y90_09530	ENOG4105EEQ	Na H antiporter
E5Y90_09540	ENOG4105CGZ	zinc metallopeptidase
E5Y90_09545	ENOG4105CKW	Inner membrane protein yedI
E5Y90_09565	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
E5Y90_09570	ENOG4105VCQ	rubredoxin
E5Y90_09575	ENOG4107QZF	nitrite reductase NADPH large subunit
E5Y90_09585	ENOG4105C5Q	Transcriptional regulator
E5Y90_09600	ENOG4107U91	Rhomboid family
E5Y90_09605	ENOG4105CV6	ABC transporter, permease
E5Y90_09610	ENOG4108I0Y	(ABC) transporter
E5Y90_09615	ENOG4108UJV	acyl-CoA thioesterase i
E5Y90_09650	ENOG4105CJ3	phosphate transporter
E5Y90_09655	ENOG4105C3R	Methionine synthase
E5Y90_09670	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E5Y90_09705	ENOG4107VMU	Membrane
E5Y90_09725	ENOG4105D78	K07001 NTE family protein
E5Y90_09740	ENOG4105CK7	Sodium proline symporter
E5Y90_09745	ENOG4105CTB	Polyprenyl synthetase
E5Y90_09750	ENOG4105C7F	AcnD-accessory protein PrpF
E5Y90_09760	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
E5Y90_09765	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E5Y90_09770	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
E5Y90_09780	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E5Y90_09795	ENOG4108YYC	ycei family
E5Y90_09805	ENOG4108IPT	Naphthoate synthase
E5Y90_09820	ENOG4108ETH	Formylglycinamide ribotide synthetase
E5Y90_09840	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E5Y90_09845	ENOG4107YD3	Thioesterase
E5Y90_09850	ENOG4105E02	MotA TolQ exbB proton channel
E5Y90_09855	ENOG4105M8F	Biopolymer transport protein exbD tolR
E5Y90_09865	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
E5Y90_09870	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E5Y90_09915	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E5Y90_09920	ENOG4105C02	permease
E5Y90_09930	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E5Y90_09945	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
E5Y90_09950	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
E5Y90_09955	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E5Y90_09975	ENOG4108UPT	UPF0178 protein
E5Y90_10010	ENOG4107KET	secretion protein, HlyD family
E5Y90_10030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5Y90_10040	ENOG4105C10	Electron transfer flavoprotein
E5Y90_10045	ENOG4105BZJ	Electron transfer flavoprotein
E5Y90_10060	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5Y90_10065	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E5Y90_10075	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E5Y90_10085	ENOG4105C85	amino acid
E5Y90_10090	ENOG4105BZG	amino acid carrier protein
E5Y90_10095	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E5Y90_10105	ENOG41082ND	Uncharacterized protein yjcO
E5Y90_10110	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E5Y90_10115	ENOG4105SYT	Methylenetetrahydrofolate reductase
E5Y90_10120	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E5Y90_10130	ENOG4105C6K	Malic enzyme
E5Y90_10140	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
E5Y90_10150	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
E5Y90_10155	ENOG4107RGD	Major Facilitator superfamily
E5Y90_10160	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_10165	ENOG4105ETT	transcriptional Regulator, LysR family
E5Y90_10180	ENOG4108RRZ	Transcription elongation factor GreB
E5Y90_10195	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
E5Y90_10200	ENOG4105E4C	Lytic transglycosylase catalytic
E5Y90_10205	ENOG4105D0M	Protease HtpX homolog
E5Y90_10215	ENOG4105CJW	magnesium transporter
E5Y90_10220	ENOG4105BZS	acriflavin resistance protein
E5Y90_10225	ENOG4107RET	Isocitrate lyase
E5Y90_10235	ENOG4105C37	(CBS) domain
E5Y90_10270	ENOG4105EEI	dihydropteroate synthase
E5Y90_10280	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E5Y90_10285	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
E5Y90_10290	ENOG4105HBR	Rna-binding protein
E5Y90_10305	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E5Y90_10310	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E5Y90_10320	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E5Y90_10325	ENOG4105EQK	-acetyltransferase
E5Y90_10345	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E5Y90_10365	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
E5Y90_10370	ENOG4105C34	Pseudouridine synthase
E5Y90_10375	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E5Y90_10380	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E5Y90_10395	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
E5Y90_10425	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E5Y90_10430	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E5Y90_10475	ENOG4107T5V	SNARE associated Golgi
E5Y90_10495	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E5Y90_10500	ENOG41084BA	UPF0250 protein
E5Y90_10505	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E5Y90_10520	ENOG4105CUB	amino acid
E5Y90_10530	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
E5Y90_10535	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E5Y90_10540	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E5Y90_10555	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
E5Y90_10565	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E5Y90_10580	ENOG410841Q	phosphoesterase PA-phosphatase related protein
E5Y90_10585	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E5Y90_10590	ENOG4105BZS	acriflavin resistance protein
E5Y90_10595	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E5Y90_10600	ENOG4105K8R	UPF0145 protein
E5Y90_10605	ENOG4105K8R	UPF0145 protein
E5Y90_10660	ENOG4108VWS	Yaeq family
E5Y90_10665	ENOG4105CKI	cobalamin synthesis protein
E5Y90_10680	ENOG4108W5M	transcriptional regulator
E5Y90_10685	ENOG4105CZM	Major Facilitator
E5Y90_10695	ENOG4108S4H	thioesterase Superfamily protein
E5Y90_10705	ENOG4105D78	K07001 NTE family protein
E5Y90_10715	ENOG4105D6U	Sodium Glutamate Symporter
E5Y90_10725	ENOG4105C2C	drug resistance transporter, Bcr CflA
E5Y90_10730	ENOG4105EM2	membrane
E5Y90_10740	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E5Y90_10800	ENOG4105WD1	Membrane
E5Y90_10830	ENOG4105C8Q	Methyl-accepting chemotaxis
E5Y90_10835	ENOG4108ZGA	chew protein
E5Y90_10840	ENOG4105M3Z	response regulator
E5Y90_10845	ENOG4108UNF	response regulator
E5Y90_10855	ENOG4105D0S	secretion protein (HlyD
E5Y90_10900	ENOG4105H1G	trap transporter solute receptor taxi family
E5Y90_10915	ENOG4105D1F	ATP-binding protein
E5Y90_10925	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E5Y90_10945	ENOG4105K6H	D-cysteine desulfhydrase
E5Y90_10950	ENOG4105CBX	hi0933 family
E5Y90_10975	ENOG4105DP0	ferredoxin-NADP reductase
E5Y90_10980	ENOG4105DUM	transcriptional regulator, lysR family
E5Y90_11000	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E5Y90_11010	ENOG4105C8S	subunit m
E5Y90_11015	ENOG4105D65	subunit l
E5Y90_11020	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5Y90_11025	ENOG4107UFS	subunit j
E5Y90_11030	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
E5Y90_11040	ENOG4108IEH	NADH dehydrogenase subunit g
E5Y90_11045	ENOG4107QIZ	NADH dehydrogenase
E5Y90_11050	ENOG4105GKE	subunit e
E5Y90_11065	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
E5Y90_11075	ENOG4105JJR	Histidine kinase
E5Y90_11080	ENOG4107EXC	regulatoR
E5Y90_11085	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5Y90_11090	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E5Y90_11130	ENOG4107XGZ	Hydrolase
E5Y90_11135	ENOG4105DWF	phosphomethylpyrimidine kinase
E5Y90_11140	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
E5Y90_11155	ENOG4105D3G	Pseudouridine synthase
E5Y90_11185	ENOG4105DTD	Dehydrogenase
E5Y90_11195	ENOG4105CY2	Citrate transporter
E5Y90_11200	ENOG4108I0Z	Aconitate hydratase
E5Y90_11205	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
E5Y90_11215	ENOG4105RK9	auxin efflux carrier
E5Y90_11220	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5Y90_11230	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
E5Y90_11235	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E5Y90_11240	ENOG4105CI3	gtp-binding protein typa
E5Y90_11245	ENOG4105C2W	permease
E5Y90_11255	ENOG4108IQI	permease
E5Y90_11275	ENOG4105CHU	acetyl-coa acetyltransferase
E5Y90_11290	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E5Y90_11300	ENOG4108R6W	Transcriptional regulator, ARAC family
E5Y90_11305	ENOG4105CHU	acetyl-coa acetyltransferase
E5Y90_11310	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
E5Y90_11330	ENOG4108UT2	hemolysin iii
E5Y90_11335	ENOG4105CSH	Transporter
E5Y90_11350	ENOG4107RZC	phospholipase d
E5Y90_11360	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E5Y90_11385	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
E5Y90_11390	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E5Y90_11395	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E5Y90_11405	ENOG4108UJD	30S ribosomal protein S9
E5Y90_11410	ENOG4107MKT	Stringent starvation protein a
E5Y90_11415	ENOG4105KB2	stringent starvation protein b
E5Y90_11455	ENOG4108KHX	Diguanylate cyclase
E5Y90_11460	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
E5Y90_11490	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E5Y90_11495	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E5Y90_11510	ENOG4105D3R	alkyl hydroperoxide reductase
E5Y90_11525	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E5Y90_11530	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E5Y90_11565	ENOG4108VIA	integral membrane protein
E5Y90_11570	ENOG4105II7	pyrroline-5-carboxylate reductase
E5Y90_11575	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E5Y90_11585	ENOG4105C9X	ppx gppa phosphatase
E5Y90_11595	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
E5Y90_11610	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
E5Y90_11615	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E5Y90_11650	ENOG4105W39	Membrane
E5Y90_11660	ENOG4105CYM	Glutathione S-transferase
E5Y90_11670	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E5Y90_11690	ENOG4105CEY	Amp-dependent synthetase and ligase
E5Y90_11705	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E5Y90_11715	ENOG4108V0P	LemA family
E5Y90_11725	ENOG4105VIE	preprotein translocase, subunit YajC
E5Y90_11730	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5Y90_11735	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E5Y90_11750	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5Y90_11765	ENOG4105C6T	cysteine synthase
E5Y90_11770	ENOG4105BZU	Histidine kinase
E5Y90_11780	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
E5Y90_11785	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
E5Y90_11820	ENOG4105C1G	acyl-Coa dehydrogenase
E5Y90_11825	ENOG4105CT3	Monooxygenase
E5Y90_11830	ENOG4108ZT0	50S ribosomal protein l17
E5Y90_11840	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E5Y90_11860	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E5Y90_11875	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E5Y90_11885	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E5Y90_11890	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E5Y90_11895	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E5Y90_11925	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E5Y90_11940	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E5Y90_11950	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E5Y90_11955	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E5Y90_11960	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E5Y90_12005	ENOG4105CK2	sodium dicarboxylate symporter
E5Y90_12010	ENOG4105C29	acyl-CoA thioesterase
E5Y90_12015	ENOG4105E55	glycerol-3-phosphate acyltransferase
E5Y90_12025	ENOG4105CB5	ATP-dependent DNA helicase recG
E5Y90_12030	ENOG4105MJ2	Competence protein
E5Y90_12040	ENOG4108URH	decarboxylase
E5Y90_12045	ENOG4107QUT	magnesium and cobalt transport protein CorA
E5Y90_12055	ENOG4105E3I	toluene tolerance
E5Y90_12060	ENOG4107PE3	Mammalian cell entry related domain protein
E5Y90_12065	ENOG4105CY3	ABC transporter, permease
E5Y90_12070	ENOG4105DHJ	ABC, transporter
E5Y90_12075	ENOG4105C1J	atp-dependent rna helicase
E5Y90_12080	ENOG4105ECY	inositol monophosphatase
E5Y90_12085	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E5Y90_12100	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E5Y90_12115	ENOG4105CSU	acyl-Coa dehydrogenase
E5Y90_12120	ENOG4105VEQ	Cold shock protein
E5Y90_12125	ENOG4105CSA	Coproporphyrinogen iii oxidase
E5Y90_12135	ENOG4107QI1	Mate efflux family protein
E5Y90_12150	ENOG4105WMR	Protein CrcB homolog
E5Y90_12165	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E5Y90_12180	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
E5Y90_12185	ENOG4105IPI	Membrane
E5Y90_12190	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E5Y90_12195	ENOG4105VCH	membrane
E5Y90_12200	ENOG4107QF7	multi-drug
E5Y90_12215	ENOG4105CQB	FAD linked oxidase domain protein
E5Y90_12220	ENOG4108JQ1	Dehydrogenase
E5Y90_12230	ENOG4107AQZ	Membrane
E5Y90_12245	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E5Y90_12250	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
E5Y90_12255	ENOG4107IFA	Lipase (EC 3.1.1.3)
E5Y90_12270	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E5Y90_12275	ENOG4105K5M	30s ribosomal protein S16
E5Y90_12320	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E5Y90_12325	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
E5Y90_12330	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5Y90_12335	ENOG4105KME	endoribonuclease L-psp
E5Y90_12340	ENOG4105W53	bacterioferritin-associated ferredoxin
E5Y90_12345	ENOG4108UQY	Iron-storage protein
E5Y90_12350	ENOG4108YSG	O-Antigen polymerase
E5Y90_12355	ENOG4108YSG	O-Antigen polymerase
E5Y90_12360	ENOG4105X0D	Fimbrial protein
E5Y90_12445	ENOG4108V0P	LemA family
E5Y90_12455	ENOG4105BZ8	glutamate synthase
E5Y90_12460	ENOG4105CBC	glutamate synthase
E5Y90_12480	ENOG4105E4G	Type IV pilus
E5Y90_12505	ENOG4108JQC	penicillin-binding protein 1A
E5Y90_12510	ENOG4105DHI	Methyltransferase
E5Y90_12515	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E5Y90_12520	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
E5Y90_12525	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E5Y90_12530	ENOG4105CJN	penicillin-binding protein
E5Y90_12545	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
E5Y90_12575	ENOG4105C5H	ABC transporter
E5Y90_12585	ENOG4105PDP	Short chain dehydrogenase
E5Y90_12590	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E5Y90_12600	ENOG4105D65	subunit l
E5Y90_12605	ENOG4108ZE9	Monovalent cation H antiporter subunit C
E5Y90_12610	ENOG4107R4Z	monovalent cation h antiporter subunit d
E5Y90_12615	ENOG4105SC1	monovalent cation H antiporter subunit E
E5Y90_12620	ENOG4105W4C	monovalent cation H antiporter subunit F
E5Y90_12625	ENOG4105KJM	monovalent cation h antiporter subunit g
E5Y90_12630	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E5Y90_12640	ENOG4105CHV	Transcription elongation factor NusA
E5Y90_12675	ENOG4107EJC	Preprotein translocase subunit SecG
E5Y90_12680	ENOG4105CP7	Triose-phosphate isomerase
E5Y90_12685	ENOG4107QHF	type ii secretion system protein e
E5Y90_12700	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
E5Y90_12710	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E5Y90_12715	ENOG4105NBK	UPF0345 protein
E5Y90_12720	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E5Y90_12730	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E5Y90_12740	ENOG4105BZ1	(ABC) transporter
E5Y90_12750	ENOG4107QJZ	Glycosyl transferase, family 2
E5Y90_12755	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
E5Y90_12760	ENOG4105DFG	type I secretion outer membrane protein
E5Y90_12775	ENOG41087AY	ADP-Ribose pyrophosphatase
E5Y90_12780	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
E5Y90_12790	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
E5Y90_12800	ENOG4105CNI	cell division protein FtsW
E5Y90_12815	ENOG4105CE1	Ferrous iron transport protein b
E5Y90_12825	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5Y90_12830	ENOG4105T95	Thiol disulfide interChange protein
E5Y90_12835	ENOG4105D6E	homoserine dehydrogenase
E5Y90_12845	ENOG41061WM	D-Alanyl-D-Alanine
E5Y90_12855	ENOG4105BZU	Histidine kinase
E5Y90_12860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E5Y90_12865	ENOG4105CN1	protease
E5Y90_12870	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E5Y90_12875	ENOG4108K5H	permease YjgP YjgQ family protein
E5Y90_12880	ENOG4108M8S	permease YjgP YjgQ family protein
E5Y90_12900	ENOG4105DQR	SNARE associated Golgi
E5Y90_12915	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E5Y90_12925	ENOG4105BZU	Histidine kinase
E5Y90_12940	ENOG4105C0P	Mg chelatase subunit ChlI
E5Y90_12950	ENOG4105J5J	Outer membrane porin
E5Y90_12955	ENOG4105F0N	pyrophosphate phospho-hydrolase
E5Y90_12970	ENOG4105CEY	Amp-dependent synthetase and ligase
E5Y90_12975	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E5Y90_12980	ENOG41079KZ	Major Facilitator Superfamily
E5Y90_12985	ENOG4105EN6	Membrane
E5Y90_12995	ENOG4105EE5	Membrane protein terC
E5Y90_13000	ENOG4108URH	decarboxylase
E5Y90_13010	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E5Y90_13020	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
E5Y90_13035	ENOG4105CCT	upf0313 protein
E5Y90_13040	ENOG4105D94	Major Facilitator Superfamily
E5Y90_13090	ENOG4105C79	DNA protecting protein DprA
E5Y90_13100	ENOG4105SX7	Transporter
E5Y90_13115	ENOG4108V06	Glutathione peroxidase
E5Y90_13140	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E5Y90_13190	ENOG4105FDK	ABC transporter
E5Y90_13195	ENOG4105FAV	ABC, transporter
E5Y90_13200	ENOG4105EWC	Purine nucleoside phosphorylase
E5Y90_13210	ENOG410829K	Lysine exporter protein (Lyse ygga)
E5Y90_13215	ENOG4105EZR	dyp-type peroxidase family protein
E5Y90_13225	ENOG4108QDE	fad dependent oxidoreductase
E5Y90_13230	ENOG4105EUB	pirin domain protein
E5Y90_13245	ENOG4105D3R	alkyl hydroperoxide reductase
E5Y90_13270	ENOG4108UUM	single-stranded DNA-binding protein
E5Y90_13275	ENOG4107RDB	Major Facilitator
E5Y90_13285	ENOG4105DWF	phosphomethylpyrimidine kinase
E5Y90_13295	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E5Y90_13310	ENOG4105C94	Transporter
E5Y90_13320	ENOG4107QN1	sodium solute
E5Y90_13325	ENOG41062QD	Membrane
E5Y90_13330	ENOG4105BZU	Histidine kinase
E5Y90_13345	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
E5Y90_13355	ENOG4105D64	Mechanosensitive ion channel
E5Y90_13365	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E5Y90_13370	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5Y90_13400	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
E5Y90_13415	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E5Y90_13435	ENOG4107QSN	dihydrolipoamide acetyltransferase
E5Y90_13440	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
E5Y90_13445	ENOG41063SB	peptidase
E5Y90_13460	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E5Y90_13465	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E5Y90_13470	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
E5Y90_13480	ENOG4105DFU	Cell wall formation (By similarity)
E5Y90_13490	ENOG4105D7Z	glutathione synthase
E5Y90_13505	ENOG4105E3B	Multicopper oxidase
E5Y90_13520	ENOG4108ZX5	transcriptional regulator
E5Y90_13525	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
E5Y90_13530	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
E5Y90_13535	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E5Y90_13545	ENOG4107QKV	phosphomannomutase
E5Y90_13550	ENOG4105CMR	udp-glucose 4-epimerase
E5Y90_13560	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E5Y90_13565	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
E5Y90_13575	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E5Y90_13580	ENOG4107WZ3	Transferase
E5Y90_13585	ENOG4105D3Q	Sugar transferase
E5Y90_13590	ENOG4105CGN	Glycosyl transferase (Group 1
E5Y90_13605	ENOG4108KMV	Glycosyl transferase (Group 1
E5Y90_13620	ENOG4107QQG	Dehydrogenase
E5Y90_13625	ENOG4105DAY	polysaccharide export protein
E5Y90_13635	ENOG4105D75	Capsular exopolysaccharide family
E5Y90_13640	ENOG4108MRJ	
E5Y90_13645	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5Y90_13650	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E5Y90_13665	ENOG4105CEN	a g-specific adenine glycosylase
E5Y90_13670	ENOG4105FAA	peptidase M23
E5Y90_13695	ENOG4108R3E	Dna-3-methyladenine glycosylase i
E5Y90_13700	ENOG4105DQ4	alcohol dehydrogenase
E5Y90_13710	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E5Y90_13725	ENOG4105KHC	sulfurtransferase
E5Y90_13745	ENOG4105D7V	transposase
E5Y90_13755	ENOG4105EAC	phosphoserine phosphatase
E5Y90_13765	ENOG4105C09	Bile acid
E5Y90_13770	ENOG4108RWI	nicotinamidase
E5Y90_13775	ENOG4108SC4	)-transporter
E5Y90_13780	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E5Y90_13790	ENOG4105C8V	SAICAR synthetase
E5Y90_13795	ENOG4105D1H	recombination factor protein RarA
E5Y90_13805	ENOG4108ZZ3	UPF0260 protein
E5Y90_13815	ENOG4105CJR	Integral membrane protein (MviN
E5Y90_13820	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
E5Y90_13825	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E5Y90_13830	ENOG4105HSS	phospholipase C
E5Y90_13835	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
E5Y90_13840	ENOG4105EJ2	Transcriptional regulator
E5Y90_13845	ENOG4108Z33	Thiol disulfide Interchange Protein
E5Y90_13850	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
E5Y90_13855	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
E5Y90_13860	ENOG4105UBK	short-chain dehydrogenase reductase
E5Y90_13880	ENOG4107QZM	n-acetylglutamate synthase
E5Y90_13885	ENOG4108R86	Transcriptional regulator
E5Y90_13895	ENOG4105DTN	riboflavin biosynthesis protein ribF
E5Y90_13900	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E5Y90_13910	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E5Y90_13950	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E5Y90_13955	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E5Y90_13960	ENOG4105CVE	Lytic murein transglycosylase
E5Y90_13965	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E5Y90_13970	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E5Y90_13980	ENOG4105DFU	Cell wall formation (By similarity)
E5Y90_13990	ENOG4105F27	Major Facilitator
E5Y90_13995	ENOG4105DU1	integral membrane protein, terc
E5Y90_14000	ENOG4107QUY	Guanine deaminase
E5Y90_14005	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E5Y90_14015	ENOG4105T95	Thiol disulfide interChange protein
E5Y90_14030	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E5Y90_14035	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
E5Y90_14040	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E5Y90_14055	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
E5Y90_14070	ENOG4105E39	Enoyl-CoA hydratase
E5Y90_14085	ENOG4105CEY	Amp-dependent synthetase and ligase
E5Y90_14410	ENOG4108UUM	single-stranded DNA-binding protein
E5Y90_14445	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E5Y90_14640	ENOG4108IG5	Transcriptional regulator
E5Y90_14840	ENOG4105M6W	Crispr-associated protein, Csy3 family
E5Y90_14850	ENOG4105ENG	CRISPR-associated protein, Csy1 family
E5Y90_15200	ENOG4105CZX	twitching motility protein
E5Y90_15275	ENOG4105DR5	peptidase
E5Y90_15460	ENOG4108K0D	peptidase, M48
E5Y90_15475	ENOG4105J7D	transcriptional regulator
E5Y90_15495	ENOG4105CHR	reductase
E5Y90_15645	ENOG4108JJ7	ABC transporter
E5Y90_15690	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E5Y90_15705	ENOG410814C	multidrug resistance protein
E5Y90_15715	ENOG4106032	Glutathionylspermidine synthase
E5Y90_15790	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
E5Y90_15815	ENOG4105KK6	nuclease
E5Y90_15945	ENOG4105F5W	AtP-binding protein
E5Y90_16010	ENOG4105CY2	Citrate transporter
E5Y90_16015	ENOG4105C0A	alcohol dehydrogenase
E5Y90_16020	ENOG4105C26	Dehydrogenase
E5Y90_16025	ENOG4108FUF	Transcriptional regulator, IclR family
E5Y90_16075	ENOG4105E4P	ATPase (AAA
E5Y90_16135	ENOG4105C26	Dehydrogenase
E5Y90_16145	ENOG4105C26	Dehydrogenase
E5Y90_16150	ENOG4105C0A	alcohol dehydrogenase
E5Y90_16190	ENOG4108FUF	Transcriptional regulator, IclR family
E5Y90_16205	ENOG4108BUD	transposase
E5Y90_16225	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
E5Y90_16280	ENOG4105EKQ	RNA-directed DNA polymerase
E5Y90_16370	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
E5Y90_16390	ENOG4108BUD	transposase
E5Y90_16400	ENOG4108C33	Resolvase
E5Y90_16410	ENOG4108R0M	Aminoglycoside
E5Y90_16435	ENOG4105W1Y	Transcriptional regulator
E5Y90_16465	ENOG4108C66	Inherit from COG: DNA primase
E5Y90_16490	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
E5Y90_16535	ENOG4105MZU	cell filamentation protein
E5Y90_16550	ENOG4105E5H	Transposase
E5Y90_16610	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
E5Y90_16670	ENOG4105IYK	transposase
E5Y90_16675	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
E5Y90_16680	ENOG4107QJE	Chromosome Partitioning Protein
E5Y90_16820	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
E5Y90_16825	ENOG4107QJE	Chromosome Partitioning Protein
E5Y90_16840	ENOG4108NE4	
E5Y90_16860	ENOG4108HWY	Beta-lactamase
E5Y90_16870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E5Y90_16875	ENOG4105BZU	Histidine kinase
E5Y90_16885	ENOG4105BZS	acriflavin resistance protein
E5Y90_16890	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E5Y90_17005	ENOG4108W2Y	isochorismatase
E5Y90_17010	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
E5Y90_17040	ENOG4105CH6	catalase
E5Y90_17100	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
E5Y90_17125	ENOG4107Z6W	Protein CrcB homolog
E5Y90_17135	ENOG4105CHH	sulfate transporter
E5Y90_17190	ENOG4105WJ3	XRE family Transcriptional regulator
E5Y90_17290	ENOG410814C	multidrug resistance protein
E5Y90_17300	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)