locus-tag	class	description
G8E00_00015	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G8E00_00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G8E00_00025	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G8E00_00050	ENOG4105PGM	cation diffusion facilitator family transporter
G8E00_00055	ENOG4105T95	Thiol disulfide interChange protein
G8E00_00060	ENOG4107BMA	Transglycosylase associated protein
G8E00_00065	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G8E00_00070	ENOG4107QUY	Guanine deaminase
G8E00_00090	ENOG4106032	Glutathionylspermidine synthase
G8E00_00110	ENOG4105DU1	integral membrane protein, terc
G8E00_00120	ENOG410830R	acetyltransferase
G8E00_00130	ENOG4105DFU	Cell wall formation (By similarity)
G8E00_00145	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G8E00_00150	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G8E00_00155	ENOG4105CVE	Lytic murein transglycosylase
G8E00_00200	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G8E00_00210	ENOG4108XC3	NADH ubiquinone oxidoreductase
G8E00_00215	ENOG4105C8J	)-transporter
G8E00_00225	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
G8E00_00230	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G8E00_00320	ENOG4105C01	Dihydroxy-acid dehydratase
G8E00_00335	ENOG4107W19	lmbE family
G8E00_00345	ENOG4108KAM	Transcriptional regulator
G8E00_00350	ENOG4105C2W	permease
G8E00_00355	ENOG4105BZU	Histidine kinase
G8E00_00370	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G8E00_00395	ENOG4105UBK	short-chain dehydrogenase reductase
G8E00_00400	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8E00_00405	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G8E00_00410	ENOG4108Z33	Thiol disulfide Interchange Protein
G8E00_00415	ENOG4105EJ2	Transcriptional regulator
G8E00_00420	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
G8E00_00445	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G8E00_00450	ENOG4105HSS	phospholipase C
G8E00_00455	ENOG4107T7U	Sulfatase
G8E00_00460	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G8E00_00465	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
G8E00_00470	ENOG4105CJR	Integral membrane protein (MviN
G8E00_00475	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G8E00_00480	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G8E00_00485	ENOG4105D75	Capsular exopolysaccharide family
G8E00_00500	ENOG4107QQG	Dehydrogenase
G8E00_00505	ENOG4107R5Z	Oxidoreductase domain protein
G8E00_00510	ENOG4105J5G	Transferase hexapeptide repeat containing protein
G8E00_00515	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G8E00_00520	ENOG4105CPK	Glycosyl transferase (Group 1
G8E00_00555	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G8E00_00560	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G8E00_00570	ENOG4105CMR	udp-glucose 4-epimerase
G8E00_00575	ENOG4107QKV	phosphomannomutase
G8E00_00580	ENOG41090SZ	ABC-2 type transporter
G8E00_00590	ENOG4105ECX	polysaccharide export
G8E00_00595	ENOG4107V1M	polysaccharide export protein
G8E00_00610	ENOG4105E12	capsule polysaccharide
G8E00_00615	ENOG41084CK	capsule polysaccharide
G8E00_00630	ENOG4105M85	Bola protein
G8E00_00640	ENOG4107QJE	Chromosome Partitioning Protein
G8E00_00655	ENOG4105DQR	SNARE associated Golgi
G8E00_00665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G8E00_00670	ENOG4106H3A	restriction
G8E00_00675	ENOG4105BZU	Histidine kinase
G8E00_00680	ENOG4105EUB	pirin domain protein
G8E00_00700	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
G8E00_00705	ENOG4105C32	Amino acid ABC transporter (Permease)
G8E00_00715	ENOG4105C0Z	ABC transporter
G8E00_00720	ENOG4108IV0	ABC, transporter
G8E00_00745	ENOG4105DHG	Allantoate amidinohydrolase
G8E00_00750	ENOG41061H0	Monooxygenase
G8E00_00765	ENOG4105C2W	permease
G8E00_00770	ENOG4105VT2	5-hydroxyisourate hydrolase
G8E00_00815	ENOG4105KUZ	arsenate reductase
G8E00_00820	ENOG4105CGK	Exodeoxyribonuclease III
G8E00_00830	ENOG4105K5X	acetyltransferase
G8E00_00850	ENOG4107RBI	VanW family
G8E00_00855	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G8E00_00860	ENOG4105D7Z	glutathione synthase
G8E00_00880	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G8E00_00885	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G8E00_00890	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G8E00_00910	ENOG41063SB	peptidase
G8E00_00915	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G8E00_00920	ENOG4107QSN	dihydrolipoamide acetyltransferase
G8E00_00945	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G8E00_00960	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G8E00_01025	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8E00_01030	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G8E00_01040	ENOG4105D64	Mechanosensitive ion channel
G8E00_01045	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G8E00_01050	ENOG4107T8P	acyl-Coa dehydrogenase
G8E00_01070	ENOG4105FBW	Monooxygenase
G8E00_01075	ENOG4108UZX	fmn reductase
G8E00_01090	ENOG4105BZU	Histidine kinase
G8E00_01095	ENOG41062QD	Membrane
G8E00_01100	ENOG4107QN1	sodium solute
G8E00_01115	ENOG4108HWY	Beta-lactamase
G8E00_01120	ENOG4105BZU	Histidine kinase
G8E00_01135	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G8E00_01145	ENOG4105ETU	transcriptional activator (TenA
G8E00_01155	ENOG4107RDB	Major Facilitator
G8E00_01160	ENOG4108UUM	single-stranded DNA-binding protein
G8E00_01165	ENOG4108FPN	Integrase
G8E00_01210	ENOG4108RCM	Nitroreductase
G8E00_01220	ENOG4105KVH	Transcriptional regulator
G8E00_01225	ENOG4105D3R	alkyl hydroperoxide reductase
G8E00_01230	ENOG4105JQN	Transcriptional regulator
G8E00_01235	ENOG4105CHJ	isochorismatase hydrolase
G8E00_01240	ENOG4105EUB	pirin domain protein
G8E00_01245	ENOG4105BZ8	glutamate synthase
G8E00_01270	ENOG4105DFH	Transport of potassium into the cell (By similarity)
G8E00_01295	ENOG4108R6W	Transcriptional regulator, ARAC family
G8E00_01300	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G8E00_01305	ENOG4105CUV	Homoserine Kinase
G8E00_01320	ENOG41061CK	Antibiotic biosynthesis monooxygenase
G8E00_01355	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G8E00_01385	ENOG4108R6G	acetyltransferase
G8E00_01395	ENOG4105CYC	Transferase
G8E00_01400	ENOG4105E0F	Histidine kinase
G8E00_01435	ENOG4105CHH	sulfate transporter
G8E00_01450	ENOG4105CBN	LysR family transcriptional regulator
G8E00_01455	ENOG4105PDP	Short chain dehydrogenase
G8E00_01465	ENOG4105C5H	ABC transporter
G8E00_01500	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8E00_01510	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8E00_01535	ENOG4105CJN	penicillin-binding protein
G8E00_01540	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G8E00_01545	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G8E00_01555	ENOG4105DHI	Methyltransferase
G8E00_01560	ENOG4108JQC	penicillin-binding protein 1A
G8E00_01585	ENOG4105E4G	Type IV pilus
G8E00_01605	ENOG4105CBC	glutamate synthase
G8E00_01610	ENOG4105BZ8	glutamate synthase
G8E00_01620	ENOG4108R6K	riboflavin synthase, subunit alpha
G8E00_01625	ENOG4105KJM	monovalent cation h antiporter subunit g
G8E00_01630	ENOG4105W4C	monovalent cation H antiporter subunit F
G8E00_01635	ENOG4105SC1	monovalent cation H antiporter subunit E
G8E00_01640	ENOG4107R4Z	monovalent cation h antiporter subunit d
G8E00_01645	ENOG4108ZE9	Monovalent cation H antiporter subunit C
G8E00_01650	ENOG4105D65	subunit l
G8E00_01655	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G8E00_01665	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G8E00_01680	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G8E00_01690	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G8E00_01700	ENOG4105CSR	polyphosphate kinase 2
G8E00_01710	ENOG4105DSY	exodeoxyribonuclease V, gamma
G8E00_01715	ENOG4107QKA	exodeoxyribonuclease V beta
G8E00_01720	ENOG4107QYX	exodeoxyribonuclease v alpha
G8E00_01735	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G8E00_01740	ENOG4107QUT	magnesium and cobalt transport protein CorA
G8E00_01745	ENOG4105Z2P	Protein of unknown function (DUF465)
G8E00_01760	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G8E00_01770	ENOG4105C25	Primosomal protein n'
G8E00_01775	ENOG4105D7Q	type ii secretion system
G8E00_01780	ENOG4108VAU	general secretion pathway protein G
G8E00_01790	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G8E00_01795	ENOG4108JU5	Magnesium and cobalt efflux protein
G8E00_01805	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
G8E00_01810	ENOG4105CS6	Rhs element vgr protein
G8E00_01835	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G8E00_01845	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G8E00_01860	ENOG4105C5X	domain protein
G8E00_01865	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
G8E00_01875	ENOG4105BZ8	glutamate synthase
G8E00_01890	ENOG4105WMR	Protein CrcB homolog
G8E00_01895	ENOG4105NRA	50s ribosomal protein l31 type b
G8E00_01905	ENOG4107QI1	Mate efflux family protein
G8E00_01915	ENOG4105CSA	Coproporphyrinogen iii oxidase
G8E00_01920	ENOG4108I6E	Sulfatase
G8E00_01925	ENOG4105C94	Transporter
G8E00_01935	ENOG4105CSU	acyl-Coa dehydrogenase
G8E00_01950	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G8E00_01955	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
G8E00_01965	ENOG4105ECY	inositol monophosphatase
G8E00_01970	ENOG4105C1J	atp-dependent rna helicase
G8E00_01975	ENOG4105DHJ	ABC, transporter
G8E00_01980	ENOG4105CY3	ABC transporter, permease
G8E00_01985	ENOG4107PE3	Mammalian cell entry related domain protein
G8E00_01990	ENOG4105E3I	toluene tolerance
G8E00_02000	ENOG4105D7N	magnesium and cobalt transport protein CorA
G8E00_02005	ENOG4108URH	decarboxylase
G8E00_02015	ENOG4105MJ2	Competence protein
G8E00_02020	ENOG4105CB5	ATP-dependent DNA helicase recG
G8E00_02040	ENOG4105E55	glycerol-3-phosphate acyltransferase
G8E00_02045	ENOG4105C29	acyl-CoA thioesterase
G8E00_02055	ENOG4105CK2	sodium dicarboxylate symporter
G8E00_02070	ENOG4105DZG	Dehydrogenase
G8E00_02075	ENOG4105KPV	Transcriptional regulator
G8E00_02085	ENOG4105D7A	ATP-binding protein
G8E00_02090	ENOG4105C28	cystathionine
G8E00_02100	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G8E00_02105	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G8E00_02110	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G8E00_02125	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G8E00_02155	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G8E00_02175	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G8E00_02180	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G8E00_02190	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G8E00_02205	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G8E00_02225	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G8E00_02230	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8E00_02235	ENOG4108ZT0	50S ribosomal protein l17
G8E00_02240	ENOG4105CT3	Monooxygenase
G8E00_02245	ENOG4105IKQ	hydratase
G8E00_02250	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
G8E00_02255	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
G8E00_02270	ENOG4108W5M	transcriptional regulator
G8E00_02275	ENOG4105FUY	alpha subunit
G8E00_02290	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
G8E00_02295	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
G8E00_02300	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
G8E00_02340	ENOG4105CSU	acyl-Coa dehydrogenase
G8E00_02345	ENOG4105E1F	short-chain dehydrogenase reductase
G8E00_02365	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
G8E00_02370	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G8E00_02400	ENOG4105DUM	transcriptional regulator, lysR family
G8E00_02415	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G8E00_02435	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G8E00_02460	ENOG4105HDK	L-asparaginase
G8E00_02500	ENOG4105D1S	lipid A biosynthesis
G8E00_02505	ENOG4106HWW	Acyltransferase family
G8E00_02530	ENOG4105CQM	Urea amidohydrolase subunit alpha
G8E00_02565	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G8E00_02580	ENOG4105C5H	ABC transporter
G8E00_02595	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
G8E00_02600	ENOG4105KVH	Transcriptional regulator
G8E00_02610	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G8E00_02625	ENOG4105BZW	Glycerate kinase
G8E00_02635	ENOG4105C4R	Atp-dependent dna helicase
G8E00_02670	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G8E00_02685	ENOG4107RGH	Aldehyde dehydrogenase
G8E00_02690	ENOG41062JF	Transcriptional regulator
G8E00_02695	ENOG4105CIY	formyltetrahydrofolate deformylase
G8E00_02710	ENOG4105M8F	Biopolymer transport protein exbD tolR
G8E00_02805	ENOG4105DWV	Homoserine O-trans-acetylase
G8E00_02810	ENOG4105DWV	Homoserine O-trans-acetylase
G8E00_02815	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G8E00_02830	ENOG4108ESX	Receptor
G8E00_02835	ENOG4108ESX	Receptor
G8E00_02845	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G8E00_02865	ENOG4107GFK	fumarate
G8E00_02875	ENOG4108DNC	Involved in acetate metabolism (By similarity)
G8E00_02880	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
G8E00_02905	ENOG4105CN1	protease
G8E00_02910	ENOG4105BZU	Histidine kinase
G8E00_02915	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G8E00_02930	ENOG4105F8V	Hydrolase, tatD family
G8E00_02935	ENOG4107QM5	aconitate hydratase
G8E00_02945	ENOG4105CUZ	uba thif-type nad fad binding protein
G8E00_02955	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G8E00_03050	ENOG4108Z4X	TRANSCRIPTIONal
G8E00_03060	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G8E00_03065	ENOG4105W8H	transhydrogenase (subunit alpha
G8E00_03070	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G8E00_03075	ENOG4108KB2	LysR family Transcriptional regulator
G8E00_03080	ENOG4107EFR	Flavocytochrome c
G8E00_03110	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G8E00_03115	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8E00_03120	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
G8E00_03125	ENOG4105BZU	Histidine kinase
G8E00_03130	ENOG4105C6T	cysteine synthase
G8E00_03145	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8E00_03160	ENOG4105DXN	mazG family
G8E00_03165	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
G8E00_03170	ENOG4105DJ0	Poly(A) Polymerase
G8E00_03175	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G8E00_03190	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G8E00_03195	ENOG41080Z8	PHOSPHOCARRIER protein
G8E00_03200	ENOG4105N42	UPF0307 protein
G8E00_03210	ENOG4105CEY	Amp-dependent synthetase and ligase
G8E00_03225	ENOG4105CBC	glutamate synthase
G8E00_03245	ENOG4105CYM	Glutathione S-transferase
G8E00_03250	ENOG4105W39	Membrane
G8E00_03300	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G8E00_03305	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G8E00_03315	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G8E00_03325	ENOG4105C9X	ppx gppa phosphatase
G8E00_03335	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G8E00_03340	ENOG4105II7	pyrroline-5-carboxylate reductase
G8E00_03345	ENOG4108VIA	integral membrane protein
G8E00_03365	ENOG4105C2M	dna polymerase I
G8E00_03385	ENOG4107QHF	type ii secretion system protein e
G8E00_03395	ENOG4108ZHJ	Organic hydroperoxide resistance protein
G8E00_03415	ENOG410903C	(LipO)protein
G8E00_03450	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_03455	ENOG4108RZE	Tetr family transcriptional regulator
G8E00_03470	ENOG4107QX3	carboxylase
G8E00_03475	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_03480	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8E00_03515	ENOG4105KB2	stringent starvation protein b
G8E00_03520	ENOG4107MKT	Stringent starvation protein a
G8E00_03530	ENOG4108UJD	30S ribosomal protein S9
G8E00_03535	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G8E00_03540	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G8E00_03545	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G8E00_03550	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
G8E00_03575	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G8E00_03585	ENOG4107RZC	phospholipase d
G8E00_03595	ENOG4105CSH	Transporter
G8E00_03600	ENOG4108UT2	hemolysin iii
G8E00_03615	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
G8E00_03620	ENOG4105PAD	Hydrolase
G8E00_03630	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8E00_03635	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_03645	ENOG4108R6W	Transcriptional regulator, ARAC family
G8E00_03675	ENOG4108ZX5	transcriptional regulator
G8E00_03695	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G8E00_03715	ENOG4105D3R	alkyl hydroperoxide reductase
G8E00_03730	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G8E00_03735	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G8E00_03760	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
G8E00_03765	ENOG4108KHX	Diguanylate cyclase
G8E00_03800	ENOG4105D2S	major facilitator superfamily
G8E00_03805	ENOG4105CDA	abc transporter atp-binding protein
G8E00_03810	ENOG4105DRP	amino acid AbC transporter
G8E00_03815	ENOG4105EAD	ABC transporter
G8E00_03845	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G8E00_03855	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G8E00_03905	ENOG4105P8F	nudix hydrolase
G8E00_03910	ENOG4108Z0R	Transferase
G8E00_03915	ENOG41072GX	Peptidase M22 Glycoprotease
G8E00_03920	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G8E00_03935	ENOG4105C4W	S-formylglutathione hydrolase
G8E00_03955	ENOG4105DJV	ribulose-phosphate 3-epimerase
G8E00_03965	ENOG4105E3B	Multicopper oxidase
G8E00_03970	ENOG4105VR0	copper resistance
G8E00_03995	ENOG4105C7K	acetolactate synthase
G8E00_04000	ENOG4105DWF	phosphomethylpyrimidine kinase
G8E00_04005	ENOG4107XGZ	Hydrolase
G8E00_04010	ENOG4105EW9	transcriptional regulator AsnC family
G8E00_04025	ENOG4105M4H	endoribonuclease L-psp
G8E00_04035	ENOG4105EXC	Acyl-transferase
G8E00_04040	ENOG4108YXA	Membrane
G8E00_04055	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G8E00_04080	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
G8E00_04090	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G8E00_04095	ENOG4105C3M	thioredoxin reductase
G8E00_04100	ENOG4105CNU	cell division protein FtsK
G8E00_04120	ENOG4107QMS	site-determining protein
G8E00_04135	ENOG4106HNH	Acyl-transferase
G8E00_04140	ENOG4108ZG0	Ompa motb domain protein
G8E00_04145	ENOG4108ZG0	Ompa motb domain protein
G8E00_04150	ENOG4105C4R	Atp-dependent dna helicase
G8E00_04155	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G8E00_04160	ENOG4107QKV	phosphomannomutase
G8E00_04165	ENOG4105CAS	nag kinase
G8E00_04170	ENOG4105E7A	Glutamine amidotransferase
G8E00_04185	ENOG4105VDB	UPF0125 protein
G8E00_04195	ENOG41090R7	Ferric uptake
G8E00_04200	ENOG4105CZX	twitching motility protein
G8E00_04205	ENOG4105DFA	alanine racemase domain protein
G8E00_04225	ENOG4105EYH	Exonuclease
G8E00_04230	ENOG4107RH8	nuclease SbcCD subunit D
G8E00_04240	ENOG4105BZU	Histidine kinase
G8E00_04245	ENOG4105D52	delta-aminolevulinic acid dehydratase
G8E00_04250	ENOG4108VUY	thioesterase Superfamily protein
G8E00_04255	ENOG4105CW7	secretion protein, HlyD family
G8E00_04260	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G8E00_04265	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G8E00_04275	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
G8E00_04290	ENOG4105D05	Receptor
G8E00_04295	ENOG4105CTK	cobaltochelatase, cobn subunit
G8E00_04310	ENOG4105E0K	tonB-dependent siderophore receptor
G8E00_04325	ENOG4105E0K	tonB-dependent siderophore receptor
G8E00_04330	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
G8E00_04380	ENOG4105BZU	Histidine kinase
G8E00_04395	ENOG4105BZU	Histidine kinase
G8E00_04400	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G8E00_04410	ENOG4105CSV	Glutaminase
G8E00_04420	ENOG4105CMT	Dihydroxyacetone kinase
G8E00_04440	ENOG4105C3R	Methionine synthase
G8E00_04445	ENOG4105CJ3	phosphate transporter
G8E00_04475	ENOG4105D05	Receptor
G8E00_04495	ENOG4108UJV	acyl-CoA thioesterase i
G8E00_04500	ENOG4108I0Y	(ABC) transporter
G8E00_04505	ENOG4105CV6	ABC transporter, permease
G8E00_04510	ENOG4107U91	Rhomboid family
G8E00_04525	ENOG4105C5Q	Transcriptional regulator
G8E00_04530	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G8E00_04535	ENOG4107QZF	nitrite reductase NADPH large subunit
G8E00_04540	ENOG4105VCQ	rubredoxin
G8E00_04545	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G8E00_04560	ENOG4108MRJ	
G8E00_04575	ENOG4105C11	sulfate adenylyltransferase), subunit 2
G8E00_04580	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
G8E00_04595	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
G8E00_04610	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
G8E00_04625	ENOG4108UHE	carbonic anhydrase
G8E00_04660	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G8E00_04680	ENOG4105K8R	UPF0145 protein
G8E00_04685	ENOG4105K8R	UPF0145 protein
G8E00_04690	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8E00_04695	ENOG4105BZS	acriflavin resistance protein
G8E00_04700	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G8E00_04705	ENOG4105EYK	Phosphatidylglycerophosphatase B
G8E00_04720	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G8E00_04730	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
G8E00_04740	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G8E00_04745	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G8E00_04750	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G8E00_04760	ENOG4105CUB	amino acid
G8E00_04775	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G8E00_04795	ENOG4108Z43	UPF0250 protein
G8E00_04820	ENOG4105C72	UPF0176 protein
G8E00_04830	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G8E00_04860	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G8E00_04890	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
G8E00_04905	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G8E00_04910	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E00_04915	ENOG4105C34	Pseudouridine synthase
G8E00_04920	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G8E00_04940	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G8E00_04950	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G8E00_04985	ENOG4105C4K	Nad synthetase
G8E00_04995	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
G8E00_05000	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
G8E00_05020	ENOG4105F95	Monooxygenase
G8E00_05035	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
G8E00_05040	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
G8E00_05050	ENOG4105E33	succinate dehydrogenase
G8E00_05055	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G8E00_05060	ENOG4105C7S	Dehydrogenase
G8E00_05065	ENOG4107QN2	dihydrolipoyl dehydrogenase
G8E00_05075	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G8E00_05085	ENOG4106H78	methyltransferase
G8E00_05090	ENOG4105CJN	penicillin-binding protein
G8E00_05115	ENOG4105CSM	endonuclease III
G8E00_05120	ENOG4108R3D	Electron transport complex
G8E00_05125	ENOG4105D82	Glutamate dehydrogenase
G8E00_05135	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
G8E00_05145	ENOG4107VAM	peptidase, m28
G8E00_05155	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G8E00_05165	ENOG4105C59	p-type ATPase
G8E00_05170	ENOG4108821	RND type efflux pump
G8E00_05180	ENOG4107R0V	Pyruvate dehydrogenase
G8E00_05185	ENOG4105CPP	Dehydrogenase, E1 component
G8E00_05200	ENOG4105CHR	reductase
G8E00_05210	ENOG41080HT	Transcriptional regulator, arsr family
G8E00_05250	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
G8E00_05280	ENOG4105C6K	Malic enzyme
G8E00_05285	ENOG4105BZU	Histidine kinase
G8E00_05290	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G8E00_05295	ENOG4105SYT	Methylenetetrahydrofolate reductase
G8E00_05300	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G8E00_05330	ENOG4108W5M	transcriptional regulator
G8E00_05335	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
G8E00_05340	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
G8E00_05345	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
G8E00_05350	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
G8E00_05355	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
G8E00_05360	ENOG4105C2W	permease
G8E00_05375	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_05380	ENOG4107QPN	acyl-Coa dehydrogenase
G8E00_05410	ENOG4108IQI	permease
G8E00_05425	ENOG4108IQI	permease
G8E00_05430	ENOG4108UPT	UPF0178 protein
G8E00_05450	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G8E00_05455	ENOG4108EC8	DNA internalization-related competence protein ComEC
G8E00_05480	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G8E00_05485	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G8E00_05490	ENOG4105C02	permease
G8E00_05535	ENOG4108JU3	Alkyl hydroperoxide reductase
G8E00_05540	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G8E00_05545	ENOG4105CFP	Peptidase U32
G8E00_05550	ENOG41082YX	Transcriptional regulator, arsr family
G8E00_05555	ENOG4107WAU	Protein tyrosine phosphatase
G8E00_05560	ENOG4105D6J	arsenicaL-resistance protein
G8E00_05565	ENOG4105CAU	Arsenical resistance protein, ArsH
G8E00_05570	ENOG4108Z6Z	Transcriptional regulator
G8E00_05585	ENOG4105DP0	ferredoxin-NADP reductase
G8E00_05590	ENOG4108R96	Methyltransferase, YaeB family
G8E00_05600	ENOG4107QHF	type ii secretion system protein e
G8E00_05615	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8E00_05620	ENOG4105DHQ	Histidine kinase
G8E00_05640	ENOG4105BZ4	penicillin-binding protein
G8E00_05645	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G8E00_05650	ENOG4105VUT	cytoplasmic protein
G8E00_05655	ENOG4108I0Q	anthranilate phosphoribosyltransferase
G8E00_05680	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
G8E00_05685	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_05695	ENOG4105CQC	Prephenate dehydratase
G8E00_05700	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G8E00_05715	ENOG4108YXU	transcriptional regulator AsnC family
G8E00_05750	ENOG4105CNA	YD repeat protein
G8E00_05775	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G8E00_05780	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G8E00_05785	ENOG4105CEP	NADH dehydrogenase
G8E00_05790	ENOG4108ZG0	Ompa motb domain protein
G8E00_05795	ENOG4105DZ1	carboxypeptidase
G8E00_05810	ENOG4105VT2	5-hydroxyisourate hydrolase
G8E00_05815	ENOG4108R99	pseudouridine synthase
G8E00_05835	ENOG4105JAB	phenazine biosynthesis protein, phzf family
G8E00_05865	ENOG4107RTG	Major Facilitator superfamily
G8E00_05870	ENOG4108IND	Tetr family transcriptional regulator
G8E00_05875	ENOG4105BZ1	(ABC) transporter
G8E00_05900	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G8E00_05920	ENOG4105D3G	Pseudouridine synthase
G8E00_05925	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
G8E00_05940	ENOG4108IQE	Amp-dependent synthetase and ligase
G8E00_05950	ENOG4105ETT	transcriptional Regulator, LysR family
G8E00_05955	ENOG4105EJ2	Transcriptional regulator
G8E00_05975	ENOG4108JPW	Aminotransferase
G8E00_05980	ENOG4105DY8	decarboxylase
G8E00_06000	ENOG4105C8U	phosphate abc transporter
G8E00_06010	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G8E00_06015	ENOG4105DRP	amino acid AbC transporter
G8E00_06025	ENOG4105CDA	abc transporter atp-binding protein
G8E00_06030	ENOG4105CT1	(ABC) transporter
G8E00_06035	ENOG4105CT1	(ABC) transporter
G8E00_06040	ENOG4105IIU	Aminopeptidase
G8E00_06045	ENOG4108ETH	Formylglycinamide ribotide synthetase
G8E00_06065	ENOG4108W5M	transcriptional regulator
G8E00_06070	ENOG4105EGD	dinuclear metal center protein, YbgI family
G8E00_06080	ENOG4105E39	Enoyl-CoA hydratase
G8E00_06100	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8E00_06110	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G8E00_06115	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G8E00_06130	ENOG4107R11	Transcriptional regulator
G8E00_06135	ENOG4108IJ6	ABC transporter
G8E00_06145	ENOG4108I5D	sulfate abc transporter
G8E00_06155	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G8E00_06160	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
G8E00_06165	ENOG4105HHA	aminodeoxychorismate lyase
G8E00_06180	ENOG4108IYU	L-aspartate oxidase
G8E00_06185	ENOG4105C0H	protease
G8E00_06205	ENOG4105C3F	Signal peptidase i
G8E00_06215	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G8E00_06220	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G8E00_06230	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G8E00_06235	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
G8E00_06240	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
G8E00_06310	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G8E00_06315	ENOG4105QNF	Outer membrane lipoprotein
G8E00_06320	ENOG4105DTR	rard protein
G8E00_06345	ENOG4105ECR	NmrA family
G8E00_06350	ENOG4105KVH	Transcriptional regulator
G8E00_06360	ENOG4105VEQ	Cold shock protein
G8E00_06365	ENOG4105EQ0	Major Facilitator superfamily
G8E00_06395	ENOG4107QS8	(LipO)protein
G8E00_06400	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G8E00_06405	ENOG4105SF0	DinB family
G8E00_06465	ENOG4105D3R	alkyl hydroperoxide reductase
G8E00_06470	ENOG4105CQ7	ATP-dependent helicase
G8E00_06485	ENOG4105EUB	pirin domain protein
G8E00_06490	ENOG4105CHR	reductase
G8E00_06505	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G8E00_06540	ENOG4108JQ9	ABC transporter
G8E00_06555	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G8E00_06560	ENOG4106FTQ	Taurine ABC transporter, periplasmic
G8E00_06565	ENOG4108IY8	ABC, transporter
G8E00_06570	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G8E00_06585	ENOG4105ESN	nucleotide-binding protein
G8E00_06590	ENOG4105C9B	Cysteine desulfurase
G8E00_06620	ENOG4107RNU	major facilitator superfamily MFS_1
G8E00_06625	ENOG4107QZF	nitrite reductase NADPH large subunit
G8E00_06630	ENOG4108IFG	nitrite reductase, (NAD(P)H)
G8E00_06645	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G8E00_06655	ENOG4108ZAF	Molybdopterin
G8E00_06660	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G8E00_06665	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G8E00_06670	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G8E00_06675	ENOG4105E0C	molybdate abc transporter
G8E00_06680	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
G8E00_06695	ENOG4105C2X	Arabinose 5-phosphate isomerase
G8E00_06710	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
G8E00_06715	ENOG4108IUZ	ABC transporter
G8E00_06720	ENOG4105DFG	type I secretion outer membrane protein
G8E00_06725	ENOG4105BZ1	(ABC) transporter
G8E00_06730	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
G8E00_06760	ENOG4108Z4U	Ferredoxin
G8E00_06800	ENOG4105C0B	DNA polymerase III (alpha subunit)
G8E00_06810	ENOG4105CHM	Aminotransferase
G8E00_06815	ENOG4105E0X	reductase
G8E00_06820	ENOG4108V06	Glutathione peroxidase
G8E00_06830	ENOG4105DWU	Membrane
G8E00_06835	ENOG4107RN6	Monooxygenase
G8E00_06840	ENOG4105D6Z	AFG1 family ATPase
G8E00_06845	ENOG4107QP3	malate synthase g
G8E00_06870	ENOG4105EE5	Membrane protein terC
G8E00_06890	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
G8E00_06895	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G8E00_06900	ENOG4105DKK	Benzoate
G8E00_06905	ENOG4108NIW	Leucine export protein LeuE
G8E00_06910	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G8E00_06915	ENOG4105F52	Transcriptional regulator
G8E00_06930	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_06935	ENOG4105CHR	reductase
G8E00_06955	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G8E00_06965	ENOG4105C0A	alcohol dehydrogenase
G8E00_06995	ENOG4105CBC	glutamate synthase
G8E00_07000	ENOG4105EZE	Cupin 4 family protein
G8E00_07020	ENOG4105BZA	Phosphoglycerate kinase
G8E00_07035	ENOG4105D2N	Aldolase
G8E00_07040	ENOG4108TZV	Membrane
G8E00_07065	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G8E00_07070	ENOG4107TSN	permease
G8E00_07090	ENOG4105CNM	Receptor
G8E00_07095	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8E00_07120	ENOG4108VEV	chaperone
G8E00_07175	ENOG4105D2S	major facilitator superfamily
G8E00_07205	ENOG4108HPI	phosphatidate Cytidylyltransferase
G8E00_07220	ENOG41077RS	Phosphatase
G8E00_07225	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
G8E00_07230	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
G8E00_07235	ENOG4108Z66	YbaK ebsC protein
G8E00_07250	ENOG4108YZT	Adenosylcobinamide kinase
G8E00_07255	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G8E00_07275	ENOG4105K59	histidine triad (HIT) protein
G8E00_07295	ENOG4105C28	cystathionine
G8E00_07305	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G8E00_07325	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G8E00_07335	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G8E00_07350	ENOG41080XP	Cbs domain
G8E00_07385	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G8E00_07425	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G8E00_07430	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G8E00_07440	ENOG4105PV3	Inner membrane protein yqiJ
G8E00_07455	ENOG41082BV	acetyltransferase
G8E00_07460	ENOG4105X0I	Fimbrial
G8E00_07490	ENOG4105HDD	phospholipase
G8E00_07520	ENOG4105CRW	Short chain fatty acid transporter
G8E00_07525	ENOG4107QNJ	CoA-transferase subunit B
G8E00_07545	ENOG4105E39	Enoyl-CoA hydratase
G8E00_07550	ENOG4107QX3	carboxylase
G8E00_07555	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_07560	ENOG4105R8C	Transcriptional regulator
G8E00_07565	ENOG4105CEY	Amp-dependent synthetase and ligase
G8E00_07570	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G8E00_07575	ENOG4105C6T	cysteine synthase
G8E00_07600	ENOG4105CEY	Amp-dependent synthetase and ligase
G8E00_07605	ENOG4105H3G	oxidoreductase
G8E00_07615	ENOG4107XM9	(LipO)protein
G8E00_07625	ENOG4105DHQ	Histidine kinase
G8E00_07630	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G8E00_07635	ENOG4105DIJ	Phosphoethanolamine transferase
G8E00_07670	ENOG4106UW1	Major Facilitator superfamily
G8E00_07675	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
G8E00_07680	ENOG4108K4C	ec 3.1.3.12
G8E00_07690	ENOG4105E39	Enoyl-CoA hydratase
G8E00_07695	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8E00_07700	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_07705	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_07710	ENOG4108SY4	MarR family Transcriptional regulator
G8E00_07720	ENOG4108IPT	Naphthoate synthase
G8E00_07730	ENOG4105CEY	Amp-dependent synthetase and ligase
G8E00_07755	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G8E00_07760	ENOG4105ESI	atpase involved in dna repair
G8E00_07765	ENOG4105MRR	Transcriptional regulator (By similarity)
G8E00_07780	ENOG4107YNJ	LysR family Transcriptional regulator
G8E00_07785	ENOG4105C26	Dehydrogenase
G8E00_07790	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G8E00_07800	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_07805	ENOG4105E39	Enoyl-CoA hydratase
G8E00_07815	ENOG4105CSH	Transporter
G8E00_07820	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
G8E00_07865	ENOG410810E	transcriptional regulator, lysR family
G8E00_07880	ENOG4105EUB	pirin domain protein
G8E00_07885	ENOG4105CHJ	isochorismatase hydrolase
G8E00_07890	ENOG4108SB3	DoxX Family
G8E00_07895	ENOG4105EUB	pirin domain protein
G8E00_07965	ENOG4105CNA	YD repeat protein
G8E00_07980	ENOG4105DDY	UPF0142 protein ycaO
G8E00_07985	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8E00_08020	ENOG4105CNA	YD repeat protein
G8E00_08050	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
G8E00_08075	ENOG4105C94	Transporter
G8E00_08105	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
G8E00_08125	ENOG4105BZ1	(ABC) transporter
G8E00_08135	ENOG4108R6W	Transcriptional regulator, ARAC family
G8E00_08145	ENOG4105CZX	twitching motility protein
G8E00_08150	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G8E00_08155	ENOG4105BZU	Histidine kinase
G8E00_08160	ENOG4105EV9	Alpha Beta Hydrolase
G8E00_08165	ENOG4105CGF	Aromatic amino acid aminotransferase
G8E00_08175	ENOG4107RZC	phospholipase d
G8E00_08185	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G8E00_08190	ENOG4105T38	integral membrane protein
G8E00_08235	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_08240	ENOG4105DQS	Transcriptional regulator
G8E00_08245	ENOG4105KAF	membrAne
G8E00_08255	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G8E00_08260	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G8E00_08275	ENOG4105CZM	Major Facilitator
G8E00_08290	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
G8E00_08305	ENOG4105CMR	udp-glucose 4-epimerase
G8E00_08345	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G8E00_08355	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G8E00_08360	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G8E00_08370	ENOG4105BZU	Histidine kinase
G8E00_08375	ENOG4105D8G	Major Facilitator superfamily
G8E00_08380	ENOG4105UCG	Domain of unknown function (DUF333)
G8E00_08410	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G8E00_08415	ENOG4105VEQ	Cold shock protein
G8E00_08435	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_08440	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_08445	ENOG4108MJ3	acetyltransferase
G8E00_08470	ENOG4105EEF	Alkane 1-monooxygenase
G8E00_08475	ENOG4105E7U	AraC family transcriptional regulator
G8E00_08480	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G8E00_08500	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
G8E00_08510	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
G8E00_08515	ENOG4108Z4V	iron-sulfur cluster assembly
G8E00_08530	ENOG4108ZIT	Ferredoxin, 2FE-2S
G8E00_08535	ENOG4105F8J	Adenylate Guanylate cyclase
G8E00_08545	ENOG4108JA2	transcriptioN-repair coupling factor
G8E00_08565	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
G8E00_08570	ENOG4105K4T	epimerase
G8E00_08585	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
G8E00_08590	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
G8E00_08595	ENOG4105VEJ	Heat shock protein
G8E00_08600	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G8E00_08605	ENOG4105Y3E	Modulates RecA activity (By similarity)
G8E00_08620	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8E00_08630	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G8E00_08640	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8E00_08645	ENOG4105DZP	Membrane-associated zinc metalloprotease
G8E00_08655	ENOG4105KNE	Phosphatidate cytidylyltransferase
G8E00_08660	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G8E00_08680	ENOG4105CUX	Signal transduction histidine kinase
G8E00_08685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8E00_08700	ENOG4105BZN	citrate synthase
G8E00_08705	ENOG4105CR4	methylisocitrate lyase
G8E00_08730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8E00_08735	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G8E00_08760	ENOG4105E66	phosphoriboisomerase A
G8E00_08765	ENOG4105C7B	Threonine dehydratase
G8E00_08775	ENOG4107ZYR	domain protein
G8E00_08780	ENOG4105CZN	Potassium uptake protein
G8E00_08790	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8E00_08795	ENOG4105EJC	lysr family transcriptional regulator
G8E00_08820	ENOG4105CPC	Aldo Keto reductase
G8E00_08825	ENOG4105EJC	lysr family transcriptional regulator
G8E00_08875	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
G8E00_08885	ENOG4105CNV	Aldolase
G8E00_08890	ENOG4108RCM	Nitroreductase
G8E00_08900	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G8E00_08910	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G8E00_08915	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G8E00_08950	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8E00_08960	ENOG4108MXF	Alpha Beta Hydrolase
G8E00_08975	ENOG4107RGD	Major Facilitator superfamily
G8E00_08980	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_08985	ENOG4105ETT	transcriptional Regulator, LysR family
G8E00_08990	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G8E00_09000	ENOG4108IJ0	Aspartate ammonia-lyase
G8E00_09005	ENOG4105CK7	Sodium proline symporter
G8E00_09010	ENOG4105EW9	transcriptional regulator AsnC family
G8E00_09015	ENOG4105C26	Dehydrogenase
G8E00_09025	ENOG4105CD8	aminopeptidase N
G8E00_09060	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
G8E00_09070	ENOG4107QUV	Domain protein
G8E00_09090	ENOG4107RR1	TRANSCRIPTIONal
G8E00_09100	ENOG4107R55	ethanolamine transporter
G8E00_09105	ENOG4105CPD	ethanolamine ammonia-lyase
G8E00_09110	ENOG4107FQ9	ethanolamine ammonia-lyase
G8E00_09130	ENOG4105DQ4	alcohol dehydrogenase
G8E00_09145	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G8E00_09150	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G8E00_09155	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
G8E00_09175	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G8E00_09185	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G8E00_09200	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
G8E00_09225	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
G8E00_09230	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G8E00_09235	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G8E00_09260	ENOG4105WQI	isochorismatase
G8E00_09265	ENOG4105WQI	isochorismatase
G8E00_09270	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
G8E00_09275	ENOG4105E4F	Isochorismate synthase
G8E00_09280	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
G8E00_09300	ENOG4105E8G	Major facilitator Superfamily
G8E00_09330	ENOG4105D05	Receptor
G8E00_09345	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
G8E00_09375	ENOG4107T8P	acyl-Coa dehydrogenase
G8E00_09390	ENOG4105D01	(LipO)protein
G8E00_09395	ENOG4105D01	(LipO)protein
G8E00_09400	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G8E00_09405	ENOG4108UMI	ABC transporter, permease
G8E00_09410	ENOG4105C3G	gtp-binding protein
G8E00_09420	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8E00_09430	ENOG4108UMN	azlc family
G8E00_09435	ENOG4105ZED	uncharacterized protein ygaH
G8E00_09440	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
G8E00_09450	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
G8E00_09465	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G8E00_09470	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G8E00_09485	ENOG4108Z6B	deaminase
G8E00_09495	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G8E00_09505	ENOG4108RTD	type II secretion system protein K
G8E00_09520	ENOG4108VAU	general secretion pathway protein G
G8E00_09530	ENOG4105F8V	Hydrolase, tatD family
G8E00_09540	ENOG4107QRG	dna polymerase iii
G8E00_09550	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G8E00_09555	ENOG4105BZ1	(ABC) transporter
G8E00_09570	ENOG4105FA0	parb-like partition protein
G8E00_09575	ENOG4107QJE	Chromosome Partitioning Protein
G8E00_09585	ENOG4108S0S	Nucleotidyl transferase
G8E00_09590	ENOG4105EHM	Aminoglycoside phosphotransferase
G8E00_09595	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G8E00_09600	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G8E00_09605	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G8E00_09615	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G8E00_09620	ENOG4105K8N	protein family UPF0079, ATPase
G8E00_09640	ENOG4105I08	Pseudouridine synthase
G8E00_09655	ENOG4108VMM	UPF0756 membrane protein
G8E00_09660	ENOG4105CUY	Mechanosensitive ion channel
G8E00_09665	ENOG4105DZ2	Transcriptional regulator
G8E00_09675	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
G8E00_09680	ENOG4105D6U	Sodium Glutamate Symporter
G8E00_09695	ENOG4107STQ	Multicopper oxidase
G8E00_09715	ENOG4107QIJ	Aconitate hydratase 2
G8E00_09730	ENOG4105MA0	exported protein
G8E00_09735	ENOG4105CFU	surface antigen
G8E00_09775	ENOG4105D06	uba thif-type nad fad binding protein
G8E00_09785	ENOG4105GVF	(ABC) transporter
G8E00_09790	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8E00_09795	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G8E00_09815	ENOG4105DEN	Luciferase family
G8E00_09820	ENOG4108Z12	YiaAB two helix domain-containing protein
G8E00_09840	ENOG4105CND	Glycosyl transferase, family 2
G8E00_09845	ENOG4107BJW	polysaccharide deacetylase
G8E00_09870	ENOG4105E2S	oxidase) subunit II
G8E00_09875	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G8E00_09880	ENOG4105CCU	oxidase (Subunit III)
G8E00_09885	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
G8E00_09915	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G8E00_09925	ENOG4105CDU	Replicative dna helicase
G8E00_09935	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G8E00_09970	ENOG4108SC4	)-transporter
G8E00_10000	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G8E00_10005	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G8E00_10010	ENOG4105C12	Phosphoribosylglycinamide synthetase
G8E00_10040	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G8E00_10045	ENOG4108UMI	ABC transporter, permease
G8E00_10090	ENOG4105D9P	serine threonine protein kinase
G8E00_10125	ENOG4105KTH	gatB Yqey
G8E00_10135	ENOG4105ERG	peptidase m48, ste24p
G8E00_10155	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G8E00_10190	ENOG41069NU	Nitroreductase
G8E00_10200	ENOG4105C1J	atp-dependent rna helicase
G8E00_10215	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G8E00_10220	ENOG4105M08	Membrane
G8E00_10225	ENOG4108K3A	Glutathione S-transferase
G8E00_10230	ENOG4105CHH	sulfate transporter
G8E00_10235	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G8E00_10270	ENOG4105CD3	dihydroorotase
G8E00_10275	ENOG4105CXT	aspartate transcarbamylase
G8E00_10315	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8E00_10325	ENOG4108UKZ	OsmC family
G8E00_10330	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
G8E00_10335	ENOG4105CPC	Aldo Keto reductase
G8E00_10350	ENOG4105ERG	peptidase m48, ste24p
G8E00_10355	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G8E00_10365	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G8E00_10375	ENOG4105CFH	Aspartokinase
G8E00_10385	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G8E00_10395	ENOG4105CPW	cytochrome b561
G8E00_10405	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
G8E00_10410	ENOG4105C7N	Xanthine uracil vitamin C permease
G8E00_10415	ENOG4105E9K	Isocitrate dehydrogenase
G8E00_10430	ENOG4105M6W	Crispr-associated protein, Csy3 family
G8E00_10440	ENOG4105ENG	CRISPR-associated protein, Csy1 family
G8E00_10460	ENOG4105F8C	transglutaminase domain-containing protein
G8E00_10470	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G8E00_10480	ENOG4105D22	carbon starvation protein
G8E00_10485	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G8E00_10490	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
G8E00_10510	ENOG4105DHU	Bile acid
G8E00_10520	ENOG4105EYM	Major Facilitator superfamily
G8E00_10525	ENOG4105DAN	ATP-dependent protease
G8E00_10535	ENOG4105M2J	Glutaredoxin
G8E00_10540	ENOG4105C8Y	Acetylornithine aminotransferase
G8E00_10545	ENOG4105EJC	lysr family transcriptional regulator
G8E00_10550	ENOG4108K5P	(LipO)protein
G8E00_10570	ENOG4105DZ1	carboxypeptidase
G8E00_10575	ENOG4108Z0R	Transferase
G8E00_10595	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G8E00_10605	ENOG4107QTF	adenylosuccinate lyase
G8E00_10620	ENOG4105ERU	peptidase
G8E00_10640	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G8E00_10650	ENOG4107YD3	Thioesterase
G8E00_10655	ENOG4105E02	MotA TolQ exbB proton channel
G8E00_10660	ENOG4105M8F	Biopolymer transport protein exbD tolR
G8E00_10670	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G8E00_10675	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G8E00_10720	ENOG4105QNF	Outer membrane lipoprotein
G8E00_10765	ENOG4105DA5	(ABC) transporter
G8E00_10770	ENOG4105E3A	(ABC) transporter
G8E00_10785	ENOG4105CNI	cell division protein FtsW
G8E00_10790	ENOG4105CVE	Lytic murein transglycosylase
G8E00_10810	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G8E00_10815	ENOG4105CE9	30S ribosomal protein S2
G8E00_10820	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G8E00_10840	ENOG4105EJC	lysr family transcriptional regulator
G8E00_10845	ENOG4105EUB	pirin domain protein
G8E00_10855	ENOG4105DSW	Fusaric acid resistance protein
G8E00_10860	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
G8E00_10865	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G8E00_10870	ENOG4107S01	Repressor protein MetJ
G8E00_10885	ENOG4108JQ5	ABC transporter
G8E00_10890	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
G8E00_10895	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
G8E00_10905	ENOG4105E9H	Lytic Murein transglycosylase
G8E00_10910	ENOG4107RZZ	dna polymerase iii epsilon subunit
G8E00_10920	ENOG4105E09	nadh pyrophosphatase
G8E00_10925	ENOG4105EBR	Carboxylesterase
G8E00_10930	ENOG4105W4M	Transport-associated protein
G8E00_10940	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
G8E00_10945	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G8E00_10955	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
G8E00_10960	ENOG4105D0A	hydroxylase
G8E00_10975	ENOG4107RAQ	aminopeptidase
G8E00_11000	ENOG4105HF0	Membrane
G8E00_11005	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
G8E00_11010	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
G8E00_11020	ENOG4108IGT	Dipeptidase
G8E00_11025	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G8E00_11080	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
G8E00_11095	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_11100	ENOG4107QNJ	CoA-transferase subunit B
G8E00_11105	ENOG4107QP7	CoA-transferase subunit A
G8E00_11130	ENOG4105DFW	ABC transporter
G8E00_11140	ENOG4108HWW	ABC transporter
G8E00_11165	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8E00_11170	ENOG4105CXG	d-lactate dehydrogenase
G8E00_11180	ENOG41073TP	transcriptional regulator
G8E00_11185	ENOG4105DAA	L-lactate
G8E00_11190	ENOG4105CGH	5'-nucleotidase
G8E00_11220	ENOG4105EKE	dihydroorotase
G8E00_11225	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
G8E00_11250	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G8E00_11260	ENOG4107V40	secretion protein, HlyD family
G8E00_11275	ENOG4105CK2	sodium dicarboxylate symporter
G8E00_11285	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8E00_11295	ENOG4105C10	Electron transfer flavoprotein
G8E00_11300	ENOG4105BZJ	Electron transfer flavoprotein
G8E00_11305	ENOG4105N14	lysine exporter protein LysE YggA
G8E00_11310	ENOG4108YXU	transcriptional regulator AsnC family
G8E00_11315	ENOG4108YYQ	gCN5-related N-acetyltransferase
G8E00_11345	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G8E00_11360	ENOG4105BZG	amino acid carrier protein
G8E00_11370	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G8E00_11385	ENOG4105C0H	protease
G8E00_11390	ENOG4107QNR	UPF0135 protein
G8E00_11395	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8E00_11430	ENOG4105CNI	cell division protein FtsW
G8E00_11435	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G8E00_11475	ENOG4105DDQ	anthranilate synthase
G8E00_11480	ENOG4107QYG	anthranilate phosphoribosyltransferase
G8E00_11485	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G8E00_11505	ENOG4105EUJ	GTP cyclohydrolase i
G8E00_11515	ENOG4105BZU	Histidine kinase
G8E00_11530	ENOG4105NX3	Membrane
G8E00_11535	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G8E00_11545	ENOG4105C2I	pirin domain protein
G8E00_11555	ENOG4108RRZ	Transcription elongation factor GreB
G8E00_11590	ENOG4105CPN	adenine deaminase
G8E00_11600	ENOG4105HEI	LysR family (Transcriptional regulator
G8E00_11605	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
G8E00_11615	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G8E00_11620	ENOG4105E4C	Lytic transglycosylase catalytic
G8E00_11625	ENOG4105D0M	Protease HtpX homolog
G8E00_11640	ENOG4105CJW	magnesium transporter
G8E00_11645	ENOG4105BZS	acriflavin resistance protein
G8E00_11650	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
G8E00_11655	ENOG41080IJ	Diacylglycerol kinase
G8E00_11670	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G8E00_11680	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G8E00_11685	ENOG4105CSH	Transporter
G8E00_11700	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G8E00_11735	ENOG4105CP2	von willebrand factor, type a
G8E00_11740	ENOG4105EEI	dihydropteroate synthase
G8E00_11745	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G8E00_11755	ENOG4105HBR	Rna-binding protein
G8E00_11770	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G8E00_11775	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G8E00_11785	ENOG4105EQK	-acetyltransferase
G8E00_11825	ENOG4105EEQ	Na H antiporter
G8E00_11830	ENOG4105CGZ	zinc metallopeptidase
G8E00_11835	ENOG4105CKW	Inner membrane protein yedI
G8E00_11845	ENOG4105PV3	Inner membrane protein yqiJ
G8E00_11850	ENOG4107S78	Band 7 protein
G8E00_11865	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
G8E00_11880	ENOG4107RET	Isocitrate lyase
G8E00_11890	ENOG4105C37	(CBS) domain
G8E00_11900	ENOG4108JJA	ABC, transporter
G8E00_11905	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
G8E00_11920	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G8E00_11975	ENOG4105D78	K07001 NTE family protein
G8E00_11990	ENOG4105CK7	Sodium proline symporter
G8E00_11995	ENOG4105CTB	Polyprenyl synthetase
G8E00_12005	ENOG4105C7F	AcnD-accessory protein PrpF
G8E00_12010	ENOG4105C85	amino acid
G8E00_12040	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
G8E00_12050	ENOG4105D8T	Acyltransferase
G8E00_12060	ENOG4105C03	ribonuclease
G8E00_12065	ENOG4108Z03	MAF-like protein
G8E00_12070	ENOG4105VQ7	Rod shape-determining protein MreD
G8E00_12075	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G8E00_12085	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G8E00_12095	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G8E00_12165	ENOG4105CND	Glycosyl transferase, family 2
G8E00_12170	ENOG4107BJW	polysaccharide deacetylase
G8E00_12185	ENOG4108VWS	Yaeq family
G8E00_12190	ENOG4105CK2	sodium dicarboxylate symporter
G8E00_12195	ENOG4105CKI	cobalamin synthesis protein
G8E00_12210	ENOG4108S4H	thioesterase Superfamily protein
G8E00_12220	ENOG4105D78	K07001 NTE family protein
G8E00_12225	ENOG4105D6U	Sodium Glutamate Symporter
G8E00_12240	ENOG4105C2C	drug resistance transporter, Bcr CflA
G8E00_12245	ENOG4105EM2	membrane
G8E00_12255	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
G8E00_12315	ENOG4105WD1	Membrane
G8E00_12345	ENOG4105C8Q	Methyl-accepting chemotaxis
G8E00_12350	ENOG4108ZGA	chew protein
G8E00_12355	ENOG4105M3Z	response regulator
G8E00_12360	ENOG4108UNF	response regulator
G8E00_12370	ENOG4105D0S	secretion protein (HlyD
G8E00_12380	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G8E00_12410	ENOG4105D7W	serine acetyltransferase
G8E00_12425	ENOG4105D1F	ATP-binding protein
G8E00_12450	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G8E00_12460	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8E00_12510	ENOG4105CBX	hi0933 family
G8E00_12540	ENOG4105DP0	ferredoxin-NADP reductase
G8E00_12545	ENOG4105DUM	transcriptional regulator, lysR family
G8E00_12555	ENOG4105VEQ	Cold shock protein
G8E00_12565	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G8E00_12575	ENOG4105C8S	subunit m
G8E00_12580	ENOG4105D65	subunit l
G8E00_12585	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8E00_12590	ENOG4107UFS	subunit j
G8E00_12595	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G8E00_12605	ENOG4108IEH	NADH dehydrogenase subunit g
G8E00_12610	ENOG4107QIZ	NADH dehydrogenase
G8E00_12615	ENOG4105GKE	subunit e
G8E00_12645	ENOG4107EXC	regulatoR
G8E00_12650	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G8E00_12655	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G8E00_12705	ENOG4105KAF	membrAne
G8E00_12710	ENOG4105YB8	TM2 domain containing protein
G8E00_12715	ENOG4109066	lysm domain bon superfamily protein
G8E00_12725	ENOG4105CHR	reductase
G8E00_12730	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G8E00_12735	ENOG4105VGS	50s ribosomal protein l32
G8E00_12740	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G8E00_12745	ENOG4108BPE	-transporting atpase
G8E00_12750	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
G8E00_12760	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G8E00_12765	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G8E00_12770	ENOG4105FE9	pseudouridine synthase
G8E00_12785	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G8E00_12790	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G8E00_12810	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8E00_12815	ENOG4108UWD	Iron-storage protein
G8E00_12820	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
G8E00_12830	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G8E00_12840	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G8E00_12850	ENOG4105HF0	Membrane
G8E00_12855	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G8E00_12860	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G8E00_12870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G8E00_12875	ENOG4106KVJ	cytochrome C assembly protein
G8E00_12880	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
G8E00_12895	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G8E00_12910	ENOG4105KWI	UPF0339 protein
G8E00_12915	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G8E00_12925	ENOG4105DSF	transport protein
G8E00_12940	ENOG4105D3G	Pseudouridine synthase
G8E00_12945	ENOG4105BZU	Histidine kinase
G8E00_12965	ENOG4105XMH	SpoVT AbrB domain protein
G8E00_12985	ENOG4108I0Z	Aconitate hydratase
G8E00_13000	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G8E00_13035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G8E00_13040	ENOG4105CHB	tonB-dependent Receptor
G8E00_13045	ENOG4105TW1	Carbohydrate-selective porin OprB
G8E00_13055	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
G8E00_13065	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G8E00_13070	ENOG4105CI3	gtp-binding protein typa
G8E00_13075	ENOG4105C2W	permease
G8E00_13085	ENOG4108IQI	permease
G8E00_13090	ENOG4105CDV	Ompa motb domain protein
G8E00_13105	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_13115	ENOG410814C	multidrug resistance protein
G8E00_13125	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G8E00_13135	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
G8E00_13145	ENOG4105DZG	Dehydrogenase
G8E00_13150	ENOG4105TW1	Carbohydrate-selective porin OprB
G8E00_13180	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G8E00_13185	ENOG4108WBT	adenosyltransferase
G8E00_13205	ENOG4105CNG	UPF0061 protein
G8E00_13215	ENOG4105MSB	protein, conserved in bacteria
G8E00_13220	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G8E00_13225	ENOG4105EB3	Histidine kinase
G8E00_13235	ENOG4105CSU	acyl-Coa dehydrogenase
G8E00_13240	ENOG4105CSU	acyl-Coa dehydrogenase
G8E00_13270	ENOG4105UGU	tonB-dependent Receptor
G8E00_13275	ENOG4105PF3	O-Antigen polymerase
G8E00_13285	ENOG4105C9M	aspartyl-trna synthetase
G8E00_13325	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G8E00_13335	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
G8E00_13340	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G8E00_13370	ENOG4108I69	Glycosyl transferases group 1
G8E00_13380	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G8E00_13390	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G8E00_13395	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G8E00_13400	ENOG4105BZU	Histidine kinase
G8E00_13410	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G8E00_13440	ENOG4105VIE	preprotein translocase, subunit YajC
G8E00_13445	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G8E00_13450	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G8E00_13465	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G8E00_13485	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
G8E00_13505	ENOG4105WVQ	Fe-S assembly protein IscX
G8E00_13535	ENOG4108ZP8	Acetolactate synthase small subunit
G8E00_13540	ENOG4105C7K	acetolactate synthase
G8E00_13565	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
G8E00_13570	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G8E00_13575	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G8E00_13585	ENOG4105E6M	Sulphatase-modifying factor protein
G8E00_13590	ENOG4105E6M	Sulphatase-modifying factor protein
G8E00_13600	ENOG4105CS6	Rhs element vgr protein
G8E00_13605	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G8E00_13615	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G8E00_13620	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G8E00_13630	ENOG4105VW4	glutaredoxin 3
G8E00_13645	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G8E00_13650	ENOG4105W5Q	DNA repair protein (RadC
G8E00_13655	ENOG4105FFC	UPF0187 protein
G8E00_13670	ENOG4105K9H	YciI-like protein
G8E00_13685	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
G8E00_13705	ENOG4105NAU	thioesterase Superfamily protein
G8E00_13770	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G8E00_13775	ENOG4105D6S	protein involved in catabolism of external DNA
G8E00_13810	ENOG4105E4C	Lytic transglycosylase catalytic
G8E00_13815	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G8E00_13820	ENOG4105C9A	Phoh family
G8E00_13830	ENOG4105D64	Mechanosensitive ion channel
G8E00_13860	ENOG4105GVF	(ABC) transporter
G8E00_13870	ENOG4105CS1	NAD(P)H quinone oxidoreductase
G8E00_13875	ENOG4107S2Z	UPF0761 membrane protein
G8E00_13880	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
G8E00_13925	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G8E00_13935	ENOG4105DGW	oligopeptidase A
G8E00_13940	ENOG4105VKU	nucleicacid-binding protein
G8E00_13975	ENOG4105C1G	acyl-Coa dehydrogenase
G8E00_13980	ENOG4107XGZ	Hydrolase
G8E00_13985	ENOG4105EI2	Pseudouridine synthase
G8E00_13990	ENOG4105C03	ribonuclease
G8E00_13995	ENOG4105J5T	Amp-dependent synthetase and ligase
G8E00_14020	ENOG41067S9	phage shock protein C, PspC
G8E00_14040	ENOG4105C8P	)-transporter
G8E00_14065	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G8E00_14075	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G8E00_14105	ENOG4105C5I	Dehydrogenase
G8E00_14155	ENOG4105IPI	Membrane
G8E00_14160	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G8E00_14165	ENOG4105VCH	membrane
G8E00_14180	ENOG4107QF7	multi-drug
G8E00_14185	ENOG4105EUB	pirin domain protein
G8E00_14210	ENOG4105CQB	FAD linked oxidase domain protein
G8E00_14215	ENOG4108JQ1	Dehydrogenase
G8E00_14220	ENOG4107AQZ	Membrane
G8E00_14240	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G8E00_14245	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
G8E00_14250	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8E00_14255	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8E00_14260	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8E00_14265	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8E00_14270	ENOG4107IFA	Lipase (EC 3.1.1.3)
G8E00_14275	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G8E00_14285	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G8E00_14290	ENOG4105K5M	30s ribosomal protein S16
G8E00_14295	ENOG4105X0D	Fimbrial protein
G8E00_14300	ENOG4108ZUW	Major pilin subunit
G8E00_14330	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G8E00_14335	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G8E00_14340	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G8E00_14345	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G8E00_14350	ENOG4105KME	endoribonuclease L-psp
G8E00_14360	ENOG4108UQY	Iron-storage protein
G8E00_14365	ENOG4108YSG	O-Antigen polymerase
G8E00_14370	ENOG4108YSG	O-Antigen polymerase
G8E00_14385	ENOG4105HA9	of methanol dehydrogenase type
G8E00_14390	ENOG4108V0P	LemA family
G8E00_14400	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G8E00_14405	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G8E00_14410	ENOG4105CHV	Transcription elongation factor NusA
G8E00_14415	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G8E00_14440	ENOG4107EJC	Preprotein translocase subunit SecG
G8E00_14450	ENOG4107QHF	type ii secretion system protein e
G8E00_14465	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G8E00_14475	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G8E00_14485	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G8E00_14500	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G8E00_14530	ENOG4105BZ1	(ABC) transporter
G8E00_14545	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G8E00_14560	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
G8E00_14580	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G8E00_14585	ENOG4105CHU	acetyl-coa acetyltransferase
G8E00_14590	ENOG4105BZU	Histidine kinase
G8E00_14610	ENOG4107ZXU	DSBA oxidoreductase
G8E00_14630	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
G8E00_14645	ENOG4105D3Y	Na H antiporter
G8E00_14675	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G8E00_14690	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G8E00_14700	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G8E00_14705	ENOG4105PM1	preprotein translocase subunit SecE
G8E00_14745	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G8E00_14755	ENOG4105GVR	general secretion pathway protein D
G8E00_14770	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
G8E00_14795	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G8E00_14800	ENOG4108NEV	two component transcriptional regulator, LytTR family
G8E00_14805	ENOG4108HRK	Histidine kinase
G8E00_14820	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G8E00_14825	ENOG4105DFG	type I secretion outer membrane protein
G8E00_14840	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G8E00_14850	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G8E00_14860	ENOG4105CNI	cell division protein FtsW
G8E00_14880	ENOG4105CE1	Ferrous iron transport protein b
G8E00_14890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G8E00_14895	ENOG4105T95	Thiol disulfide interChange protein
G8E00_14900	ENOG4105D6E	homoserine dehydrogenase
G8E00_14915	ENOG41061WM	D-Alanyl-D-Alanine
G8E00_14925	ENOG4107TUY	Histidine kinase
G8E00_14930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G8E00_14935	ENOG4105CN1	protease
G8E00_14940	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G8E00_14945	ENOG4108K5H	permease YjgP YjgQ family protein
G8E00_14950	ENOG4108M8S	permease YjgP YjgQ family protein
G8E00_14970	ENOG4105DQR	SNARE associated Golgi
G8E00_14985	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G8E00_14990	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G8E00_14995	ENOG4105BZU	Histidine kinase
G8E00_15000	ENOG4108YZA	Nitrogen regulatory protein pii
G8E00_15010	ENOG4105C0P	Mg chelatase subunit ChlI
G8E00_15020	ENOG4105CHH	sulfate transporter
G8E00_15035	ENOG41082YX	Transcriptional regulator, arsr family
G8E00_15045	ENOG4105D6J	arsenicaL-resistance protein
G8E00_15050	ENOG4105CAU	Arsenical resistance protein, ArsH
G8E00_15055	ENOG4105C3M	thioredoxin reductase
G8E00_15060	ENOG4105H3G	oxidoreductase
G8E00_15090	ENOG4105C0P	Mg chelatase subunit ChlI
G8E00_15105	ENOG4105J5J	Outer membrane porin
G8E00_15110	ENOG4105F0N	pyrophosphate phospho-hydrolase
G8E00_15125	ENOG4105CEY	Amp-dependent synthetase and ligase
G8E00_15130	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8E00_15135	ENOG41079KZ	Major Facilitator Superfamily
G8E00_15140	ENOG4105EN6	Membrane
G8E00_15145	ENOG4105K5B	UPF0225 protein
G8E00_15150	ENOG4105EE5	Membrane protein terC
G8E00_15155	ENOG4108URH	decarboxylase
G8E00_15160	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G8E00_15170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G8E00_15175	ENOG4105CSH	Transporter
G8E00_15195	ENOG4105CCT	upf0313 protein
G8E00_15205	ENOG4105D94	Major Facilitator Superfamily
G8E00_15270	ENOG4105C79	DNA protecting protein DprA
G8E00_15290	ENOG4108V06	Glutathione peroxidase
G8E00_15320	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
G8E00_15350	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G8E00_15400	ENOG4105FDK	ABC transporter
G8E00_15405	ENOG4105FAV	ABC, transporter
G8E00_15410	ENOG4105CUY	Mechanosensitive ion channel
G8E00_15415	ENOG4108NIW	Leucine export protein LeuE
G8E00_15420	ENOG410829K	Lysine exporter protein (Lyse ygga)
G8E00_15425	ENOG4105EZR	dyp-type peroxidase family protein
G8E00_15455	ENOG4107R1I	NAD-dependent malic enzyme
G8E00_15480	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8E00_15485	ENOG4105IPS	esterase
G8E00_15510	ENOG4105D9M	gamma-glutamylcysteine synthetase
G8E00_15525	ENOG4106BRA	Membrane
G8E00_15530	ENOG4105EXC	Acyl-transferase
G8E00_15535	ENOG4105EXC	Acyl-transferase
G8E00_15540	ENOG4105CHM	Aminotransferase
G8E00_15545	ENOG4107QJQ	Mate efflux family protein
G8E00_15565	ENOG4107SM7	Transcriptional regulator
G8E00_15570	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8E00_15580	ENOG4105I5W	Transporter
G8E00_15585	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8E00_15625	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G8E00_15630	ENOG4105BZU	Histidine kinase
G8E00_15640	ENOG4105KHC	sulfurtransferase
G8E00_15685	ENOG4105EAC	phosphoserine phosphatase
G8E00_15695	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G8E00_15710	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G8E00_15715	ENOG4108ZAI	phosphatidylglycerophosphatase a
G8E00_15725	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G8E00_15760	ENOG4105D85	methylase
G8E00_15765	ENOG4105F6A	helicase
G8E00_15775	ENOG4105ECI	YeeC-like protein
G8E00_15790	ENOG4107TSN	permease
G8E00_15810	ENOG4105EWC	Purine nucleoside phosphorylase
G8E00_15820	ENOG4105C09	Bile acid
G8E00_15825	ENOG4108RWI	nicotinamidase
G8E00_15830	ENOG4108SC4	)-transporter
G8E00_15835	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G8E00_15855	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
G8E00_15865	ENOG4105D1H	recombination factor protein RarA
G8E00_15875	ENOG4108ZZ3	UPF0260 protein
G8E00_15890	ENOG4105K59	histidine triad (HIT) protein
G8E00_15895	ENOG4105CEN	a g-specific adenine glycosylase
G8E00_15910	ENOG4108R3E	Dna-3-methyladenine glycosylase i
G8E00_15925	ENOG4105F27	Major Facilitator
G8E00_15950	ENOG4107QZM	n-acetylglutamate synthase
G8E00_15955	ENOG4105GVF	(ABC) transporter
G8E00_15960	ENOG4105GVF	(ABC) transporter
G8E00_15965	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
G8E00_15970	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G8E00_15975	ENOG4108VM9	ABC, transporter
G8E00_15980	ENOG4108W9H	Tetr family transcriptional regulator
G8E00_15990	ENOG4105DTN	riboflavin biosynthesis protein ribF
G8E00_15995	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G8E00_16005	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G8E00_16105	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G8E00_16165	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
G8E00_16185	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G8E00_16195	ENOG4105VUF	Transcriptional regulator
G8E00_16210	ENOG4105C5H	ABC transporter
G8E00_16215	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G8E00_16220	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G8E00_16225	ENOG4105N0V	mono-oxygenase ydhR
G8E00_16235	ENOG4105EXG	Transcriptional regulator
G8E00_16250	ENOG4108821	RND type efflux pump
G8E00_16255	ENOG4108821	RND type efflux pump
G8E00_16260	ENOG4108821	RND type efflux pump
G8E00_16270	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G8E00_16280	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)