locus-tag	class	description
C3F22_00010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3F22_00020	COG0237	dephospho-CoA kinase activity
C3F22_00040	COG0149	triose-phosphate isomerase activity
C3F22_00075	COG0779	Required for maturation of 30S ribosomal subunits
C3F22_00080	COG0195	Participates in both transcription termination and antitermination
C3F22_00090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C3F22_00100	COG2212	antiporter activity
C3F22_00110	COG0651	ATP synthesis coupled electron transport
C3F22_00115	COG1006	Multisubunit Na H antiporter MnhC subunit
C3F22_00120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3F22_00120	COG2111	Na H antiporter
C3F22_00135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C3F22_00140	COG4221	oxidoreductase activity
C3F22_00150	COG0488	(ABC) transporter
C3F22_00190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_00200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_00205	COG0275	rRNA processing
C3F22_00220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C3F22_00225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3F22_00230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C3F22_00235	COG2226	methyltransferase
C3F22_00285	COG0069	glutamate synthase activity
C3F22_00285	COG0067	glutamate synthase
C3F22_00285	COG0070	glutamate synthase
C3F22_00290	COG0493	'glutamate synthase
C3F22_00295	COG1704	LemA family
C3F22_00350	COG3620	sequence-specific DNA binding
C3F22_00430	COG3307	-O-antigen
C3F22_00440	COG2906	2 iron, 2 sulfur cluster binding
C3F22_00450	COG0675	Transposase, IS605 OrfB family
C3F22_00455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3F22_00460	COG1758	RNA polymerase activity
C3F22_00465	COG0194	GDP metabolic process
C3F22_00510	COG0228	four-way junction DNA binding
C3F22_00515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C3F22_00525	COG0335	large ribosomal subunit rRNA binding
C3F22_00535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C3F22_00540	COG5380	lipid catabolic process
C3F22_00545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C3F22_00580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3F22_00585	COG0277	FAD linked oxidase domain protein
C3F22_00610	COG2814	Major facilitator Superfamily
C3F22_00615	COG1289	transmembrane transporter activity
C3F22_00625	COG0628	permease
C3F22_00630	COG1192	Involved in chromosome partitioning
C3F22_00660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3F22_00665	COG0254	rRNA binding
C3F22_00670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C3F22_00680	COG0534	Mate efflux family protein
C3F22_00690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3F22_00700	COG1278	Cold shock
C3F22_00705	COG1960	acyl-CoA dehydrogenase activity
C3F22_00720	COG0408	coproporphyrinogen oxidase activity
C3F22_00725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3F22_00735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C3F22_00745	COG0513	Belongs to the DEAD box helicase family
C3F22_00750	COG1127	ABC transporter
C3F22_00755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C3F22_00760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C3F22_00765	COG2854	intermembrane phospholipid transfer
C3F22_00775	COG0598	Magnesium transport protein CorA
C3F22_00790	COG1040	competence protein
C3F22_00795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3F22_00810	COG2937	Belongs to the GPAT DAPAT family
C3F22_00815	COG1946	Acyl-CoA thioesterase
C3F22_00820	COG1301	dicarboxylic acid transport
C3F22_00855	COG1959	2 iron, 2 sulfur cluster binding
C3F22_00860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C3F22_00860	COG1017	nitric oxide dioxygenase activity
C3F22_00865	COG0433	COG0433 Predicted ATPase
C3F22_00870	COG0626	cystathionine gamma-synthase activity
C3F22_00885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C3F22_00890	COG0088	Forms part of the polypeptide exit tunnel
C3F22_00905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C3F22_00950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C3F22_00955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C3F22_00960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C3F22_00970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C3F22_00990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C3F22_00995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C3F22_01000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C3F22_01005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C3F22_01010	COG0202	RNA polymerase activity
C3F22_01015	COG0203	ribosomal protein L17
C3F22_01020	COG2072	flavoprotein involved in K transport
C3F22_01025	COG1960	acyl-CoA dehydrogenase activity
C3F22_01030	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C3F22_01065	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C3F22_01070	COG0339	signal peptide processing
C3F22_01080	COG0557	exoribonuclease II activity
C3F22_01120	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3F22_01130	COG1295	ribonuclease BN
C3F22_01195	COG1702	phosphate starvation-inducible protein PhoH
C3F22_01200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3F22_01205	COG1196	nuclear chromosome segregation
C3F22_01205	COG0741	lytic transglycosylase activity
C3F22_01205	COG0739	heme binding
C3F22_01245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C3F22_01250	COG1183	phosphatidylcholine synthase activity
C3F22_01305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_01305	COG3453	Protein conserved in bacteria
C3F22_01320	COG1607	acyl-coa hydrolase
C3F22_01350	COG2350	Protein conserved in bacteria
C3F22_01365	COG3781	membrane
C3F22_01370	COG2003	Belongs to the UPF0758 family
C3F22_01375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3F22_01385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3F22_01395	COG2814	Major facilitator Superfamily
C3F22_01405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C3F22_01410	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C3F22_01415	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C3F22_01425	COG3622	Belongs to the hyi family
C3F22_01430	COG2084	Dehydrogenase
C3F22_01435	COG1024	Enoyl-CoA hydratase
C3F22_01440	COG0784	Response regulator, receiver
C3F22_01440	COG5002	protein histidine kinase activity
C3F22_01440	COG2205	protein histidine kinase activity
C3F22_01445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3F22_01460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3F22_01475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3F22_01485	COG1862	Preprotein translocase
C3F22_01500	COG1704	LemA family
C3F22_01510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C3F22_01520	COG3293	Transposase
C3F22_01525	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_01550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C3F22_01575	COG0625	glutathione transferase activity
C3F22_01585	COG1238	metal cluster binding
C3F22_01600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C3F22_01610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C3F22_01615	COG0072	phenylalanine-tRNA ligase activity
C3F22_01650	COG0037	tRNA processing
C3F22_01695	COG1764	response to oxidative stress
C3F22_01700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3F22_01775	COG2969	positive regulation of protein catabolic process
C3F22_01780	COG0625	glutathione transferase activity
C3F22_01785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C3F22_01790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C3F22_01795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C3F22_01800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C3F22_01805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3F22_01835	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3F22_01845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3F22_01850	COG1408	metallophosphoesterase
C3F22_01860	COG0477	Major facilitator Superfamily
C3F22_01865	COG1272	protein, Hemolysin III
C3F22_01885	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3F22_01885	COG1024	Enoyl-CoA hydratase
C3F22_01890	COG0183	Belongs to the thiolase family
C3F22_01895	COG2207	Transcriptional regulator
C3F22_01905	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_01920	COG0183	Belongs to the thiolase family
C3F22_01930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C3F22_01930	COG2885	chlorophyll binding
C3F22_01940	COG0833	amino acid
C3F22_01950	COG2233	PERMEase
C3F22_01980	COG1902	pentaerythritol trinitrate reductase activity
C3F22_01995	COG0354	folic acid binding
C3F22_02000	COG2132	Multicopper oxidase
C3F22_02005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C3F22_02050	COG0564	pseudouridine synthase activity
C3F22_02070	COG2824	Alkylphosphonate utilization operon protein PhnA
C3F22_02085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3F22_02085	COG0351	phosphomethylpyrimidine kinase
C3F22_02085	COG0352	thiamine-phosphate diphosphorylase activity
C3F22_02110	COG3152	Membrane
C3F22_02150	COG2223	nitrite transmembrane transporter activity
C3F22_02205	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_02215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3F22_02225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C3F22_02225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3F22_02230	COG0745	RESPONSE REGULATOR receiver
C3F22_02235	COG2205	protein histidine kinase activity
C3F22_02245	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3F22_02265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C3F22_02280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3F22_02285	COG0839	Belongs to the complex I subunit 6 family
C3F22_02290	COG0713	ATP synthesis coupled electron transport
C3F22_02295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3F22_02300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3F22_02335	COG0583	DNA-binding transcription factor activity
C3F22_02355	COG0668	transmembrane transport
C3F22_02360	COG2081	HI0933 family
C3F22_02370	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C3F22_02385	COG0004	ammonium transporteR
C3F22_02390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_02430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3F22_02430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3F22_02440	COG0489	protein tyrosine kinase activity
C3F22_02530	COG0840	transmembrane signaling receptor activity
C3F22_02560	COG2832	Protein of unknown function (DUF454)
C3F22_02620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C3F22_02630	COG1289	transmembrane transporter activity
C3F22_02635	COG2814	Major facilitator Superfamily
C3F22_02645	COG0786	glutamate:sodium symporter activity
C3F22_02650	COG1115	amino acid carrier protein
C3F22_02660	COG2059	Chromate
C3F22_02665	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3F22_02670	COG1607	acyl-coa hydrolase
C3F22_02685	COG0583	DNA-binding transcription factor activity
C3F22_02690	COG0625	glutathione transferase activity
C3F22_02705	COG0523	cobalamin synthesis protein
C3F22_02710	COG4681	YaeQ
C3F22_02715	COG1285	pathogenesis
C3F22_02725	COG2199	diguanylate cyclase activity
C3F22_02725	COG2203	Gaf domain
C3F22_02765	COG0393	Putative heavy-metal-binding
C3F22_02770	COG0393	Putative heavy-metal-binding
C3F22_02775	COG1538	Outer membrane efflux protein
C3F22_02785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_02790	COG0671	phosphoesterase, PA-phosphatase related
C3F22_02805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C3F22_02815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C3F22_02830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C3F22_02835	COG1648	precorrin-2 dehydrogenase activity
C3F22_02835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C3F22_02840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3F22_02845	COG4372	Transposase
C3F22_02855	COG2963	transposase activity
C3F22_02865	COG0531	amino acid
C3F22_02885	COG0321	lipoyl(octanoyl) transferase activity
C3F22_02895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3F22_02915	COG0586	Pfam SNARE associated Golgi protein
C3F22_02940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3F22_02965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C3F22_02970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C3F22_03000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C3F22_03010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C3F22_03015	COG0358	DNA primase activity
C3F22_03025	COG0564	pseudouridine synthase activity
C3F22_03050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3F22_03070	COG0110	maltose O-acetyltransferase activity
C3F22_03075	COG0251	oxidation-reduction process
C3F22_03080	COG1309	transcriptional regulator
C3F22_03090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C3F22_03095	COG0505	Belongs to the CarA family
C3F22_03120	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C3F22_03125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3F22_03135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3F22_03170	COG1253	flavin adenine dinucleotide binding
C3F22_03190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3F22_03200	COG2239	Acts as a magnesium transporter
C3F22_03210	COG0501	Belongs to the peptidase M48B family
C3F22_03215	COG0739	heme binding
C3F22_03215	COG0741	lytic transglycosylase activity
C3F22_03215	COG1196	nuclear chromosome segregation
C3F22_03220	COG0037	tRNA processing
C3F22_03230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C3F22_03235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C3F22_03250	COG0583	DNA-binding transcription factor activity
C3F22_03255	COG1960	acyl-CoA dehydrogenase activity
C3F22_03265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C3F22_03275	COG4372	Transposase
C3F22_03315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3F22_03320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C3F22_03325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C3F22_03355	COG1115	amino acid carrier protein
C3F22_03360	COG1113	amino acid transport
C3F22_03385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C3F22_03395	COG1522	sequence-specific DNA binding
C3F22_03400	COG1280	lysine exporter protein (LysE YggA)
C3F22_03440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_03460	COG1671	Belongs to the UPF0178 family
C3F22_03480	COG1136	(ABC) transporter
C3F22_03485	COG2333	competence protein COMEC
C3F22_03485	COG0658	competence protein
C3F22_03500	COG2267	carboxylic ester hydrolase activity
C3F22_03505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3F22_03510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C3F22_03515	COG0628	permease
C3F22_03550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3F22_03575	COG0823	Involved in the tonB-independent uptake of proteins
C3F22_03595	COG0824	Thioesterase
C3F22_03600	COG1473	amidohydrolase
C3F22_03605	COG2255	four-way junction helicase activity
C3F22_03625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C3F22_03625	COG0047	phosphoribosylformylglycinamidine synthase activity
C3F22_03635	COG0583	DNA-binding transcription factor activity
C3F22_03685	COG0778	Nitroreductase
C3F22_03690	COG1024	Enoyl-CoA hydratase
C3F22_03695	COG1056	cytidyltransferase-related domain
C3F22_03695	COG1051	belongs to the nudix hydrolase family
C3F22_03700	COG2353	YceI-like domain
C3F22_03710	COG1279	arginine transmembrane transporter activity
C3F22_03715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3F22_03725	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C3F22_03730	COG0602	queuosine metabolic process
C3F22_03750	COG0583	DNA-binding transcription factor activity
C3F22_03755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C3F22_03760	COG4208	sulfate ABC transporter
C3F22_03765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C3F22_03775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_03780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C3F22_03790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3F22_03815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3F22_03840	COG0571	ribonuclease III activity
C3F22_03845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C3F22_03855	COG1381	Involved in DNA repair and RecF pathway recombination
C3F22_03860	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C3F22_03890	COG0534	Mate efflux family protein
C3F22_03900	COG0024	Methionine aminopeptidase
C3F22_03905	COG0052	Belongs to the universal ribosomal protein uS2 family
C3F22_03930	COG2951	lytic endotransglycosylase activity
C3F22_03945	COG0842	Transport permease protein
C3F22_03950	COG1131	(ABC) transporter
C3F22_04010	COG2862	Uncharacterized protein family, UPF0114
C3F22_04030	COG3634	alkyl hydroperoxide reductase activity
C3F22_04035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C3F22_04075	COG1720	tRNA m6t6A37 methyltransferase activity
C3F22_04100	COG3293	Transposase
C3F22_04115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3F22_04125	COG0745	RESPONSE REGULATOR receiver
C3F22_04130	COG0642	Histidine kinase
C3F22_04145	COG0494	nUDIX hydrolase
C3F22_04155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3F22_04160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C3F22_04165	COG3139	Protein of unknown function (DUF1315)
C3F22_04175	COG1301	dicarboxylic acid transport
C3F22_04185	COG1960	acyl-CoA dehydrogenase activity
C3F22_04190	COG0693	protein deglycase activity
C3F22_04200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C3F22_04205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C3F22_04235	COG2252	PERMEase
C3F22_04240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C3F22_04255	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C3F22_04265	COG0527	aspartate kinase activity
C3F22_04270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3F22_04280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3F22_04310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C3F22_04335	COG1252	NADH dehydrogenase
C3F22_04340	COG1686	Belongs to the peptidase S11 family
C3F22_04355	COG2351	hydroxyisourate hydrolase activity
C3F22_04375	COG1187	pseudouridine synthase activity
C3F22_04400	COG0436	Aminotransferase
C3F22_04405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_04410	COG0386	Belongs to the glutathione peroxidase family
C3F22_04420	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C3F22_04440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C3F22_04455	COG0012	GTP binding
C3F22_04460	COG2011	ABC-type metal ion transport system permease component
C3F22_04465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C3F22_04470	COG1464	Belongs to the NlpA lipoprotein family
C3F22_04510	COG0204	Acyl-transferase
C3F22_04570	COG0804	urea catabolic process
C3F22_04590	COG2351	hydroxyisourate hydrolase activity
C3F22_04595	COG2233	PERMEase
C3F22_04610	COG4266	Belongs to the allantoicase family
C3F22_04615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_04620	COG0583	DNA-binding transcription factor activity
C3F22_04650	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C3F22_04675	COG1401	restriction endodeoxyribonuclease activity
C3F22_04675	COG1401	restriction endodeoxyribonuclease activity
C3F22_04685	COG0210	DNA helicase
C3F22_04690	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C3F22_04695	COG1484	DNA-dependent DNA replication
C3F22_04700	COG4584	PFAM Integrase catalytic
C3F22_04700	COG2390	Transcriptional regulator
C3F22_04790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C3F22_04790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C3F22_04795	COG1254	Belongs to the acylphosphatase family
C3F22_04830	COG3634	alkyl hydroperoxide reductase activity
C3F22_04850	COG0450	alkyl hydroperoxide reductase
C3F22_04855	COG1643	Atp-dependent helicase
C3F22_04875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3F22_04880	COG2707	UPF0756 membrane protein
C3F22_04905	COG0802	atpase or kinase
C3F22_04910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C3F22_04920	COG1923	regulation of RNA biosynthetic process
C3F22_04925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3F22_04935	COG3178	'Phosphotransferase
C3F22_04940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3F22_04950	COG1192	Involved in chromosome partitioning
C3F22_04955	COG1475	DNA binding
C3F22_04960	COG0811	peptide transport
C3F22_04970	COG1132	(ABC) transporter
C3F22_04975	COG1663	tetraacyldisaccharide 4'-kinase activity
C3F22_04995	COG0084	hydrolase, TatD family'
C3F22_05000	COG1309	transcriptional regulator
C3F22_05030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C3F22_05040	COG0590	tRNA wobble adenosine to inosine editing
C3F22_05050	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C3F22_05060	COG0776	regulation of translation
C3F22_05080	COG2431	L-lysine efflux transmembrane transporter activity
C3F22_05095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C3F22_05100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C3F22_05135	COG1253	flavin adenine dinucleotide binding
C3F22_05155	COG0308	aminopeptidase N
C3F22_05165	COG0589	response to stress
C3F22_05170	COG0589	response to stress
C3F22_05185	COG3135	benzoate transporter
C3F22_05195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C3F22_05210	COG0183	Belongs to the thiolase family
C3F22_05235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3F22_05240	COG0824	Thioesterase
C3F22_05245	COG1454	alcohol dehydrogenase
C3F22_05250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C3F22_05270	COG0069	glutamate synthase activity
C3F22_05280	COG2308	Evidence 4 Homologs of previously reported genes of
C3F22_05290	COG1305	Transglutaminase-like
C3F22_05305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3F22_05310	COG0305	Participates in initiation and elongation during chromosome replication
C3F22_05325	COG0360	Binds together with S18 to 16S ribosomal RNA
C3F22_05340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C3F22_05345	COG1845	cytochrome c oxidase, subunit III
C3F22_05350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C3F22_05355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C3F22_05385	COG2963	transposase activity
C3F22_05395	COG4372	Transposase
C3F22_05400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_05415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C3F22_05420	COG2890	protein-(glutamine-N5) methyltransferase activity
C3F22_05425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3F22_05430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3F22_05455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3F22_05470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3F22_05480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C3F22_05500	COG0477	Major facilitator Superfamily
C3F22_05505	COG0729	surface antigen
C3F22_05520	COG1570	exodeoxyribonuclease VII activity
C3F22_05560	COG0786	glutamate:sodium symporter activity
C3F22_05585	COG1114	Component of the transport system for branched-chain amino acids
C3F22_05590	COG0024	Methionine aminopeptidase
C3F22_05595	COG0583	DNA-binding transcription factor activity
C3F22_05600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C3F22_05615	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3F22_05615	COG1902	pentaerythritol trinitrate reductase activity
C3F22_05650	COG0148	phosphopyruvate hydratase activity
C3F22_05665	COG0772	Belongs to the SEDS family
C3F22_05680	COG4890	Cyd operon protein YbgT
C3F22_05685	COG1294	oxidase, subunit
C3F22_05735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C3F22_05755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3F22_05765	COG0133	tryptophan synthase activity
C3F22_05770	COG0516	GMP reductase activity
C3F22_05770	COG0517	IMP dehydrogenase activity
C3F22_05805	COG0612	Peptidase, M16
C3F22_05810	COG0552	protein localization to endoplasmic reticulum
C3F22_05825	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C3F22_05865	COG1960	acyl-CoA dehydrogenase activity
C3F22_05950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C3F22_05955	COG0730	response to heat
C3F22_05960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3F22_05965	COG2207	Transcriptional regulator
C3F22_05970	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3F22_05975	COG3293	Transposase
C3F22_05980	COG1960	acyl-CoA dehydrogenase activity
C3F22_05995	COG1476	TRANSCRIPTIONal
C3F22_06020	COG1271	oxidase subunit
C3F22_06025	COG1294	oxidase, subunit
C3F22_06035	COG1525	nuclease
C3F22_06095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3F22_06100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C3F22_06110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C3F22_06125	COG2814	Major facilitator Superfamily
C3F22_06130	COG0509	glycine decarboxylation via glycine cleavage system
C3F22_06140	COG1132	(ABC) transporter
C3F22_06150	COG0668	transmembrane transport
C3F22_06165	COG3122	Protein conserved in bacteria
C3F22_06180	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_06190	COG0640	Transcriptional regulator
C3F22_06195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3F22_06205	COG0789	Transcriptional regulator
C3F22_06220	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_06230	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C3F22_06235	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_06250	COG0183	Belongs to the thiolase family
C3F22_06270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3F22_06275	COG0183	Belongs to the thiolase family
C3F22_06280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3F22_06285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C3F22_06290	COG3135	benzoate transporter
C3F22_06295	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_06300	COG0543	2 iron, 2 sulfur cluster binding
C3F22_06300	COG0633	Ferredoxin
C3F22_06305	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C3F22_06310	COG4638	Rieske (2fe-2S)
C3F22_06320	COG4829	muconolactone delta-isomerase
C3F22_06325	COG4948	Mandelate Racemase Muconate Lactonizing
C3F22_06330	COG0583	DNA-binding transcription factor activity
C3F22_06335	COG2814	Major facilitator Superfamily
C3F22_06345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3F22_06355	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_06375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C3F22_06405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3F22_06410	COG1309	transcriptional regulator
C3F22_06440	COG1944	ATP diphosphatase activity
C3F22_06450	COG1960	acyl-CoA dehydrogenase activity
C3F22_06455	COG1960	acyl-CoA dehydrogenase activity
C3F22_06460	COG2814	Major facilitator Superfamily
C3F22_06470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3F22_06480	COG2814	Major facilitator Superfamily
C3F22_06490	COG2814	Major facilitator Superfamily
C3F22_06500	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3F22_06505	COG0183	Belongs to the thiolase family
C3F22_06515	COG0235	Class ii aldolase
C3F22_06520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3F22_06525	COG1024	Enoyl-CoA hydratase
C3F22_06535	COG1960	acyl-CoA dehydrogenase activity
C3F22_06540	COG2267	carboxylic ester hydrolase activity
C3F22_06555	COG2814	Major facilitator Superfamily
C3F22_06560	COG2814	Major facilitator Superfamily
C3F22_06575	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_06580	COG1136	(ABC) transporter
C3F22_06585	COG0640	Transcriptional regulator
C3F22_06615	COG2132	Multicopper oxidase
C3F22_06645	COG4773	Receptor
C3F22_06650	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
C3F22_06655	COG2116	formate transmembrane transporter activity
C3F22_06660	COG0515	serine threonine protein kinase
C3F22_06720	COG1289	transmembrane transporter activity
C3F22_06760	COG2801	Transposase and inactivated derivatives
C3F22_06765	COG4772	TonB-dependent receptor
C3F22_06810	COG1129	ABC transporter
C3F22_06835	COG0583	DNA-binding transcription factor activity
C3F22_06845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_06850	COG4266	Belongs to the allantoicase family
C3F22_06865	COG2233	PERMEase
C3F22_06870	COG2351	hydroxyisourate hydrolase activity
C3F22_06900	COG0804	urea catabolic process
C3F22_06915	COG0829	nickel cation binding
C3F22_06930	COG0830	nickel cation binding
C3F22_06945	COG0410	ABC transporter
C3F22_06960	COG0559	Belongs to the binding-protein-dependent transport system permease family
C3F22_07065	COG0596	Alpha beta hydrolase
C3F22_07100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3F22_07140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C3F22_07155	COG0439	Biotin carboxylase
C3F22_07165	COG3706	GGDEF domain
C3F22_07175	COG2814	Major facilitator Superfamily
C3F22_07205	COG5499	transcription regulator containing HTH domain
C3F22_07210	COG4680	protein conserved in bacteria
C3F22_07230	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_07240	COG1058	Belongs to the CinA family
C3F22_07240	COG1546	Belongs to the CinA family
C3F22_07250	COG0372	Belongs to the citrate synthase family
C3F22_07265	COG3293	Transposase
C3F22_07285	COG0542	response to heat
C3F22_07290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C3F22_07310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C3F22_07315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C3F22_07320	COG0569	domain protein
C3F22_07325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3F22_07345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3F22_07355	COG1585	Membrane protein implicated in regulation of membrane protease activity
C3F22_07375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3F22_07395	COG1959	2 iron, 2 sulfur cluster binding
C3F22_07405	COG0822	iron-sulfur transferase activity
C3F22_07410	COG0316	Belongs to the HesB IscA family
C3F22_07440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3F22_07450	COG1027	Aspartate ammonia-lyase
C3F22_07460	COG1522	sequence-specific DNA binding
C3F22_07475	COG0506	proline dehydrogenase activity
C3F22_07475	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C3F22_07475	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C3F22_07495	COG3781	membrane
C3F22_07500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C3F22_07540	COG0697	spore germination
C3F22_07565	COG0424	maF-like protein
C3F22_07570	COG2850	peptidyl-arginine hydroxylation
C3F22_07590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C3F22_07595	COG0702	epimerase
C3F22_07600	COG0268	Binds directly to 16S ribosomal RNA
C3F22_07610	COG1218	3'(2'),5'-bisphosphate nucleotidase
C3F22_07615	COG1011	Hydrolase
C3F22_07620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3F22_07630	COG2137	regulation of response to DNA damage stimulus
C3F22_07650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C3F22_07655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3F22_07670	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3F22_07685	COG0575	Belongs to the CDS family
C3F22_07690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C3F22_07710	COG3852	Histidine kinase
C3F22_07725	COG0445	tRNA wobble uridine modification
C3F22_07760	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C3F22_07765	COG0138	bifunctional purine biosynthesis protein purh
C3F22_07785	COG1464	Belongs to the NlpA lipoprotein family
C3F22_07790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C3F22_07795	COG2011	ABC-type metal ion transport system permease component
C3F22_07830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C3F22_07875	COG2963	transposase activity
C3F22_07885	COG4372	Transposase
C3F22_07895	COG1137	ATPase activity
C3F22_07900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C3F22_07910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C3F22_07915	COG0517	IMP dehydrogenase activity
C3F22_07915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C3F22_07950	COG0625	glutathione transferase activity
C3F22_07955	COG0519	Catalyzes the synthesis of GMP from XMP
C3F22_07955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C3F22_07975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C3F22_07995	COG2391	methyltransferase activity
C3F22_08055	COG2267	carboxylic ester hydrolase activity
C3F22_08095	COG0352	thiamine-phosphate diphosphorylase activity
C3F22_08110	COG3025	triphosphatase activity
C3F22_08130	COG0612	Peptidase, M16
C3F22_08160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_08230	COG3293	Transposase
C3F22_08245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C3F22_08250	COG1610	YqeY-like protein
C3F22_08260	COG4783	chaperone-mediated protein folding
C3F22_08265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3F22_08315	COG0778	Nitroreductase
C3F22_08325	COG0513	Belongs to the DEAD box helicase family
C3F22_08345	COG2363	Small membrane protein
C3F22_08370	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3F22_08380	COG0659	secondary active sulfate transmembrane transporter activity
C3F22_08385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C3F22_08405	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_08410	COG1309	transcriptional regulator
C3F22_08415	COG1960	acyl-CoA dehydrogenase activity
C3F22_08420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C3F22_08425	COG1024	Enoyl-CoA hydratase
C3F22_08445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3F22_08450	COG2031	fatty acid transporter
C3F22_08465	COG0540	Belongs to the ATCase OTCase family
C3F22_08495	COG0667	Aldo Keto reductase
C3F22_08505	COG1765	OsmC-like protein
C3F22_08510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3F22_08535	COG0714	Associated with various cellular activities
C3F22_08540	COG2879	small protein
C3F22_08545	COG1966	Carbon starvation protein
C3F22_08550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C3F22_08590	COG1067	ATP-dependent peptidase activity
C3F22_08595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C3F22_08600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3F22_08605	COG0583	DNA-binding transcription factor activity
C3F22_08630	COG1686	Belongs to the peptidase S11 family
C3F22_08635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C3F22_08645	COG0488	(ABC) transporter
C3F22_08650	COG3293	Transposase
C3F22_08660	COG0488	(ABC) transporter
C3F22_08665	COG2755	lipolytic protein G-D-S-L family
C3F22_08665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3F22_08675	COG0482	sulfurtransferase activity
C3F22_08695	COG3385	transposase activity
C3F22_08710	COG0616	signal peptide processing
C3F22_08720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C3F22_08735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3F22_08740	COG1113	amino acid transport
C3F22_08745	COG3961	Belongs to the TPP enzyme family
C3F22_08750	COG1522	sequence-specific DNA binding
C3F22_08755	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_08765	COG0076	glutamate decarboxylase activity
C3F22_08770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3F22_08780	COG0671	phosphoesterase, PA-phosphatase related
C3F22_08785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3F22_08805	COG1733	regulation of RNA biosynthetic process
C3F22_08825	COG3040	lipid binding
C3F22_08830	COG0556	nucleotide-excision repair
C3F22_08870	COG2175	clavaminate synthase activity
C3F22_08885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C3F22_08890	COG1960	acyl-CoA dehydrogenase activity
C3F22_08900	COG2084	Dehydrogenase
C3F22_08905	COG2233	PERMEase
C3F22_08910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3F22_08915	COG0251	oxidation-reduction process
C3F22_08920	COG1335	isochorismatase
C3F22_08925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_08930	COG0596	Alpha beta hydrolase
C3F22_08940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3F22_08945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3F22_08950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3F22_08990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C3F22_08995	COG3161	chorismate lyase activity
C3F22_09015	COG0512	Glutamine amidotransferase of anthranilate synthase
C3F22_09020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C3F22_09055	COG3706	GGDEF domain
C3F22_09070	COG3739	integral membrane protein
C3F22_09085	COG1741	Belongs to the pirin family
C3F22_09115	COG1546	Belongs to the CinA family
C3F22_09115	COG1058	Belongs to the CinA family
C3F22_09135	COG0281	malic enzyme
C3F22_09175	COG3706	GGDEF domain
C3F22_09190	COG1785	Belongs to the alkaline phosphatase family
C3F22_09195	COG1785	Belongs to the alkaline phosphatase family
C3F22_09215	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3F22_09215	COG1902	pentaerythritol trinitrate reductase activity
C3F22_09230	COG3706	GGDEF domain
C3F22_09235	COG0418	dihydroorotase activity
C3F22_09240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3F22_09260	COG0833	amino acid
C3F22_09300	COG4239	(ABC) transporter, permease
C3F22_09305	COG4174	ABC transporter (Permease)
C3F22_09310	COG4166	transmembrane transport
C3F22_09315	COG0741	lytic transglycosylase activity
C3F22_09315	COG1388	LysM domain
C3F22_09330	COG2816	NAD+ diphosphatase activity
C3F22_09350	COG3107	peptidoglycan biosynthetic process
C3F22_09365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_09370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3F22_09390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3F22_09400	COG2155	Conserved Protein
C3F22_09405	COG0006	proline dipeptidase activity
C3F22_09430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C3F22_09440	COG2234	aminopeptidase activity
C3F22_09445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C3F22_09450	COG3384	dioxygenase
C3F22_09460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3F22_09465	COG2878	Part of a membrane complex involved in electron transport
C3F22_09470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3F22_09495	COG0768	penicillin binding
C3F22_09500	COG0742	ribosomal rna small subunit methyltransferase
C3F22_09515	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_09550	COG0459	protein refolding
C3F22_09565	COG1803	Methylglyoxal synthase
C3F22_09565	COG1597	lipid kinase activity
C3F22_09580	COG0477	Major facilitator Superfamily
C3F22_09595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C3F22_09630	COG3118	belongs to the thioredoxin family
C3F22_09660	COG0175	sulfate reduction
C3F22_09675	COG2268	Band 7 protein
C3F22_09680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3F22_09690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3F22_09705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3F22_09710	COG1053	succinate dehydrogenase
C3F22_09715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C3F22_09720	COG2009	succinate dehydrogenase
C3F22_09735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3F22_09735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C3F22_09750	COG0589	response to stress
C3F22_09775	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_09810	COG3328	transposase activity
C3F22_09820	COG2321	neutral zinc metallopeptidase
C3F22_09825	COG2354	Protein conserved in bacteria
C3F22_09830	COG3293	Transposase
C3F22_09860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3F22_09865	COG1773	rubredoxin
C3F22_09870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_09880	COG0583	DNA-binding transcription factor activity
C3F22_09900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3F22_09910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C3F22_09915	COG4181	ATPase activity
C3F22_09945	COG3293	Transposase
C3F22_09950	COG4771	TonB-dependent receptor
C3F22_09965	COG4607	ABC-type enterochelin transport system periplasmic component
C3F22_09975	COG0306	phosphate transporter
C3F22_10000	COG3328	transposase activity
C3F22_10020	COG2376	Dihydroxyacetone kinase
C3F22_10025	COG2066	Belongs to the glutaminase family
C3F22_10030	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_10040	COG0525	valine-tRNA ligase activity
C3F22_10050	COG2852	Protein conserved in bacteria
C3F22_10065	COG2323	membrane
C3F22_10070	COG0546	phosphoglycolate phosphatase activity
C3F22_10090	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3F22_10105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3F22_10110	COG0142	geranyltranstransferase activity
C3F22_10115	COG2828	Protein conserved in bacteria
C3F22_10120	COG1113	amino acid transport
C3F22_10140	COG0560	Phosphoserine phosphatase
C3F22_10150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3F22_10155	COG1530	ribonuclease E activity
C3F22_10160	COG0424	maF-like protein
C3F22_10165	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C3F22_10170	COG1792	Involved in formation and maintenance of cell shape
C3F22_10175	COG1077	Cell shape determining protein MreB Mrl
C3F22_10180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C3F22_10190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C3F22_10210	COG0697	spore germination
C3F22_10220	COG3590	peptidase
C3F22_10225	COG3590	peptidase
C3F22_10245	COG3293	Transposase
C3F22_10250	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C3F22_10260	COG3328	transposase activity
C3F22_10270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C3F22_10275	COG2223	nitrite transmembrane transporter activity
C3F22_10285	COG0500	methyltransferase
C3F22_10310	COG0783	Belongs to the Dps family
C3F22_10335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C3F22_10340	COG4149	molybdate abc transporter
C3F22_10345	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3F22_10350	COG0303	'Molybdopterin
C3F22_10355	COG0315	cyclic pyranopterin monophosphate synthase activity
C3F22_10355	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3F22_10360	COG0314	molybdopterin synthase activity
C3F22_10370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3F22_10380	COG0243	molybdopterin cofactor binding
C3F22_10385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_10390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3F22_10395	COG2223	nitrite transmembrane transporter activity
C3F22_10405	COG0582	viral genome integration into host DNA
C3F22_10450	COG4372	Transposase
C3F22_10465	COG0629	single-stranded DNA binding
C3F22_10495	COG3617	BRO family, N-terminal domain
C3F22_10535	COG0582	viral genome integration into host DNA
C3F22_10545	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_10565	COG2186	Transcriptional regulator
C3F22_10570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3F22_10580	COG2084	Dehydrogenase
C3F22_10590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3F22_10600	COG0583	DNA-binding transcription factor activity
C3F22_10610	COG0129	dihydroxy-acid dehydratase activity
C3F22_10615	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_10640	COG3177	Filamentation induced by cAMP protein fic
C3F22_10675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3F22_10695	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_10705	COG3293	Transposase
C3F22_10765	COG0131	Imidazoleglycerol-phosphate dehydratase
C3F22_10765	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C3F22_10780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C3F22_10785	COG2814	Major facilitator Superfamily
C3F22_10790	COG1566	PFAM secretion protein HlyD family protein
C3F22_10795	COG2050	protein possibly involved in aromatic compounds catabolism
C3F22_10805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3F22_10810	COG1090	epimerase
C3F22_10820	COG0420	3'-5' exonuclease activity
C3F22_10850	COG0735	belongs to the Fur family
C3F22_10855	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C3F22_10860	COG2914	Belongs to the UPF0125 (RnfH) family
C3F22_10875	COG0121	glutamine amidotransferase
C3F22_10910	COG0756	dUTP diphosphatase activity
C3F22_10920	COG2885	chlorophyll binding
C3F22_10925	COG0204	Acyl-transferase
C3F22_10935	COG0850	regulation of cytokinetic process
C3F22_10940	COG2894	cell division
C3F22_10955	COG1674	ftsk spoiiie
C3F22_10955	COG0531	amino acid
C3F22_10965	COG0492	ferredoxin-NADP+ reductase activity
C3F22_10970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C3F22_10980	COG0456	acetyltransferase
C3F22_11005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C3F22_11025	COG1113	amino acid transport
C3F22_11030	COG0251	oxidation-reduction process
C3F22_11045	COG1522	sequence-specific DNA binding
C3F22_11050	COG1652	LysM domain
C3F22_11055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3F22_11060	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_11070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C3F22_11075	COG1399	metal-binding, possibly nucleic acid-binding protein
C3F22_11080	COG3101	peptidyl-lysine hydroxylation
C3F22_11085	COG0009	L-threonylcarbamoyladenylate synthase
C3F22_11100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C3F22_11105	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C3F22_11135	COG0339	signal peptide processing
C3F22_11145	COG4166	transmembrane transport
C3F22_11155	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C3F22_11175	COG2193	ferroxidase activity
C3F22_11180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3F22_11185	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C3F22_11190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C3F22_11200	COG1196	nuclear chromosome segregation
C3F22_11215	COG0730	response to heat
C3F22_11230	COG3545	Serine hydrolase
C3F22_11240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3F22_11250	COG2226	methyltransferase
C3F22_11260	COG3327	negative regulation of DNA-templated transcription, initiation
C3F22_11265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C3F22_11270	COG0183	Belongs to the thiolase family
C3F22_11275	COG1024	Enoyl-CoA hydratase
C3F22_11280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C3F22_11285	COG2151	metal-sulfur cluster biosynthetic enzyme
C3F22_11290	COG3396	Phenylacetate-CoA oxygenase
C3F22_11295	COG3460	Phenylacetate-CoA oxygenase
C3F22_11300	COG3396	Phenylacetate-CoA oxygenase
C3F22_11305	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_11305	COG2030	dehydratase
C3F22_11310	COG2814	Major facilitator Superfamily
C3F22_11330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3F22_11335	COG2076	Multidrug Resistance protein
C3F22_11340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3F22_11360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C3F22_11375	COG1968	undecaprenyl-diphosphatase activity
C3F22_11380	COG1214	PFAM Peptidase M22, glycoprotease
C3F22_11390	COG0494	nUDIX hydrolase
C3F22_11480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C3F22_11485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C3F22_11570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C3F22_11575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C3F22_11590	COG0450	alkyl hydroperoxide reductase
C3F22_11605	COG0285	dihydrofolate synthase activity
C3F22_11640	COG0133	tryptophan synthase activity
C3F22_11650	COG4206	TonB-dependent receptor
C3F22_11655	COG2096	Adenosyltransferase
C3F22_11670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C3F22_11675	COG2315	Protein conserved in bacteria
C3F22_11685	COG1113	amino acid transport
C3F22_11695	COG0745	RESPONSE REGULATOR receiver
C3F22_11700	COG2205	protein histidine kinase activity
C3F22_11710	COG1960	acyl-CoA dehydrogenase activity
C3F22_11715	COG1960	acyl-CoA dehydrogenase activity
C3F22_11760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C3F22_11815	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C3F22_11820	COG2205	protein histidine kinase activity
C3F22_11835	COG1660	Displays ATPase and GTPase activities
C3F22_11850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3F22_11855	COG0617	tRNA 3'-terminal CCA addition
C3F22_11860	COG1596	polysaccharide export
C3F22_11860	COG1555	photosystem II stabilization
C3F22_11865	COG3956	TIGRFAM MazG family protein
C3F22_11870	COG4221	oxidoreductase activity
C3F22_11880	COG0675	Transposase, IS605 OrfB family
C3F22_11885	COG1943	Transposase
C3F22_11925	COG1426	Protein conserved in bacteria
C3F22_11945	COG2975	iron-sulfur cluster assembly
C3F22_11970	COG0028	Belongs to the TPP enzyme family
C3F22_11980	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_12015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_12020	COG1136	(ABC) transporter
C3F22_12020	COG0577	efflux transmembrane transporter activity
C3F22_12025	COG1538	Outer membrane efflux protein
C3F22_12035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3F22_12045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C3F22_12050	COG1162	GTPase activity
C3F22_12060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C3F22_12080	COG0084	hydrolase, TatD family'
C3F22_12095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C3F22_12125	COG2203	Gaf domain
C3F22_12125	COG3706	GGDEF domain
C3F22_12125	COG4251	negative regulation of phosphorylation
C3F22_12125	COG5001	Diguanylate cyclase
C3F22_12175	COG0793	Belongs to the peptidase S41A family
C3F22_12200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C3F22_12205	COG0857	belongs to the CobB CobQ family
C3F22_12205	COG0280	phosphate acetyltransferase
C3F22_12215	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C3F22_12215	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C3F22_12230	COG0740	serine-type endopeptidase activity
C3F22_12240	COG4774	siderophore transport
C3F22_12250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C3F22_12255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3F22_12260	COG2813	Specifically methylates the guanine in position
C3F22_12260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3F22_12320	COG3040	lipid binding
C3F22_12330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3F22_12365	COG0788	formyltetrahydrofolate deformylase activity
C3F22_12380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C3F22_12385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C3F22_12390	COG4651	solute:proton antiporter activity
C3F22_12390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3F22_12405	COG0724	RNA recognition motif
C3F22_12410	COG0210	DNA helicase
C3F22_12415	COG1929	Belongs to the glycerate kinase type-1 family
C3F22_12465	COG2900	Belongs to the SlyX family
C3F22_12475	COG1560	Kdo2-lipid A biosynthetic process
C3F22_12535	COG0473	3-isopropylmalate dehydrogenase activity
C3F22_12550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C3F22_12605	COG0753	catalase activity
C3F22_12645	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3F22_12650	COG3384	dioxygenase
C3F22_12655	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_12670	COG4638	Rieske (2fe-2S)
C3F22_12675	COG0583	DNA-binding transcription factor activity
C3F22_12695	COG4569	acetaldehyde dehydrogenase (acetylating) activity
C3F22_12700	COG3971	2-oxopent-4-enoate hydratase activity
C3F22_12705	COG0546	phosphoglycolate phosphatase activity
C3F22_12720	COG1530	ribonuclease E activity
C3F22_12725	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_12750	COG1983	PspC domain protein
C3F22_12760	COG0471	metal ion transport
C3F22_12780	COG0751	glycine-tRNA ligase activity
C3F22_12805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3F22_12820	COG2226	methyltransferase
C3F22_12830	COG0644	oxidoreductase
C3F22_12840	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C3F22_12850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3F22_12865	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C3F22_12875	COG0644	oxidoreductase
C3F22_12875	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C3F22_12890	COG3501	Rhs element vgr protein
C3F22_12910	COG0425	Belongs to the sulfur carrier protein TusA family
C3F22_12915	COG4535	Mg2 and Co2 transporter CorC
C3F22_12940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3F22_12950	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C3F22_12975	COG0789	Transcriptional regulator
C3F22_12980	COG2841	Protein conserved in bacteria
C3F22_12990	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C3F22_12995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3F22_13000	COG1074	ATP-dependent DNA helicase activity
C3F22_13005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C3F22_13025	COG2226	methyltransferase
C3F22_13035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C3F22_13065	COG0745	RESPONSE REGULATOR receiver
C3F22_13080	COG0427	acetyl-CoA hydrolase
C3F22_13085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3F22_13115	COG0326	Molecular chaperone. Has ATPase activity
C3F22_13125	COG3047	cAMP biosynthetic process
C3F22_13130	COG2056	Na+-H+ antiporter family
C3F22_13150	COG4372	Transposase
C3F22_13170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C3F22_13175	COG0085	RNA polymerase activity
C3F22_13185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C3F22_13245	COG0546	phosphoglycolate phosphatase activity
C3F22_13275	COG0824	Thioesterase
C3F22_13295	COG0181	hydroxymethylbilane synthase activity
C3F22_13305	COG3275	phosphorelay sensor kinase activity
C3F22_13335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3F22_13365	COG1024	Enoyl-CoA hydratase
C3F22_13365	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3F22_13440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C3F22_13485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3F22_13535	COG3158	transport of potassium into the cell
C3F22_13585	COG0450	alkyl hydroperoxide reductase
C3F22_13600	COG0629	single-stranded DNA binding
C3F22_13605	COG2814	Major facilitator Superfamily
C3F22_13625	COG0351	phosphomethylpyrimidine kinase
C3F22_13625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3F22_13625	COG0352	thiamine-phosphate diphosphorylase activity
C3F22_13660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3F22_13670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3F22_13675	COG3162	membrane
C3F22_13680	COG0784	Response regulator, receiver
C3F22_13680	COG2198	Histidine kinase
C3F22_13680	COG2205	protein histidine kinase activity
C3F22_13695	COG0431	NADPH-dependent FMN reductase
C3F22_13705	COG0307	riboflavin synthase, alpha
C3F22_13720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3F22_13730	COG0668	transmembrane transport
C3F22_13735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3F22_13740	COG1519	Transferase
C3F22_13745	COG1902	pentaerythritol trinitrate reductase activity
C3F22_13770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3F22_13795	COG0426	domain, Protein
C3F22_13795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3F22_13800	COG2119	membrane
C3F22_13830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C3F22_13840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C3F22_13850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C3F22_13865	COG0189	ligase activity
C3F22_13885	COG0708	Exodeoxyribonuclease III
C3F22_13905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C3F22_13960	COG3150	esterase
C3F22_13970	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C3F22_13975	COG2918	glutathione biosynthetic process
C3F22_13990	COG2733	membrane
C3F22_14030	COG0753	catalase activity
C3F22_14050	COG0560	Phosphoserine phosphatase
C3F22_14050	COG3830	Belongs to the UPF0237 family
C3F22_14065	COG0385	Bile acid
C3F22_14070	COG1335	isochorismatase
C3F22_14080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3F22_14090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C3F22_14095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C3F22_14100	COG3300	MHYT domain
C3F22_14100	COG5001	Diguanylate cyclase
C3F22_14105	COG2983	Belongs to the UPF0260 family
C3F22_14110	COG5487	UPF0391 membrane protein
C3F22_14120	COG3023	N-Acetylmuramoyl-L-alanine amidase
C3F22_14130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C3F22_14140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3F22_14145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C3F22_14150	COG0546	phosphoglycolate phosphatase activity
C3F22_14155	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_14180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C3F22_14180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C3F22_14185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3F22_14190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3F22_14195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3F22_14200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3F22_14205	COG1116	anion transmembrane transporter activity
C3F22_14210	COG1309	transcriptional regulator
C3F22_14220	COG0196	riboflavin kinase activity
C3F22_14225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C3F22_14235	COG1047	Peptidyl-prolyl cis-trans
C3F22_14255	COG2133	pyrroloquinoline quinone binding
C3F22_14260	COG3706	GGDEF domain
C3F22_14260	COG5001	Diguanylate cyclase
C3F22_14260	COG2203	Gaf domain
C3F22_14260	COG4251	negative regulation of phosphorylation
C3F22_14310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3F22_14380	COG0488	(ABC) transporter
C3F22_14385	COG1063	alcohol dehydrogenase
C3F22_14395	COG0187	DNA topoisomerase II activity
C3F22_14405	COG0592	DNA-directed DNA polymerase activity
C3F22_14410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C3F22_14415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C3F22_14420	COG0594	ribonuclease P activity
C3F22_14425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C3F22_14430	COG0706	membrane insertase activity
C3F22_14475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3F22_14490	COG0402	S-adenosylhomocysteine deaminase activity
C3F22_14495	COG0861	Integral membrane protein TerC family
C3F22_14500	COG2814	Major facilitator Superfamily
C3F22_14530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C3F22_14545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C3F22_14550	COG2951	lytic endotransglycosylase activity
C3F22_14555	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C3F22_14560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C3F22_14595	COG2814	Major facilitator Superfamily
C3F22_14600	COG2814	Major facilitator Superfamily
C3F22_14615	COG0693	protein deglycase activity
C3F22_14630	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_14635	COG0733	neurotransmitter:sodium symporter activity
C3F22_14645	COG0428	transporter
C3F22_14660	COG0129	dihydroxy-acid dehydratase activity
C3F22_14665	COG0129	dihydroxy-acid dehydratase activity
C3F22_14690	COG2233	PERMEase
C3F22_14710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_14760	COG0675	Transposase, IS605 OrfB family
C3F22_14770	COG1064	alcohol dehydrogenase
C3F22_14775	COG2818	Glycosylase
C3F22_14785	COG0739	heme binding
C3F22_14790	COG1194	a g-specific adenine glycosylase
C3F22_14820	COG1596	polysaccharide export
C3F22_14830	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C3F22_14860	COG0463	Glycosyl transferase, family 2
C3F22_14875	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_14900	COG4372	Transposase
C3F22_14910	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_14925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3F22_14955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C3F22_15000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3F22_15010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3F22_15020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C3F22_15030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3F22_15045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3F22_15050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3F22_15095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C3F22_15105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3F22_15110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C3F22_15120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C3F22_15160	COG4716	Myosin-crossreactive antigen
C3F22_15175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C3F22_15175	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3F22_15180	COG1105	Belongs to the carbohydrate kinase PfkB family
C3F22_15185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C3F22_15185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3F22_15185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3F22_15195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3F22_15200	COG3550	peptidyl-serine autophosphorylation
C3F22_15255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3F22_15270	COG0531	amino acid
C3F22_15305	COG1203	CRISPR-associated helicase, Cas3
C3F22_15330	COG3756	Protein conserved in bacteria
C3F22_15375	COG1192	Involved in chromosome partitioning
C3F22_15390	COG0586	Pfam SNARE associated Golgi protein
C3F22_15395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C3F22_15395	COG0519	Catalyzes the synthesis of GMP from XMP
C3F22_15405	COG3706	GGDEF domain
C3F22_15455	COG0534	Mate efflux family protein
C3F22_15460	COG0436	Aminotransferase
C3F22_15465	COG3501	Rhs element vgr protein
C3F22_15520	COG3328	transposase activity
C3F22_15530	COG2837	iron assimilation
C3F22_15535	COG1280	lysine exporter protein (LysE YggA)
C3F22_15545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3F22_15550	COG1121	(ABC) transporter
C3F22_15600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C3F22_15610	COG1012	belongs to the aldehyde dehydrogenase family
C3F22_15625	COG0386	Belongs to the glutathione peroxidase family
C3F22_15630	COG0386	Belongs to the glutathione peroxidase family
C3F22_15635	COG0697	spore germination
C3F22_15650	COG0758	DNA mediated transformation
C3F22_15705	COG2814	Major facilitator Superfamily
C3F22_15725	COG0477	Major facilitator Superfamily
C3F22_15730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3F22_15755	COG1253	flavin adenine dinucleotide binding
C3F22_15765	COG2860	membrane
C3F22_15770	COG0477	Major facilitator Superfamily
C3F22_15780	COG0318	PFAM AMP-dependent synthetase and ligase
C3F22_15795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C3F22_15815	COG0606	chelatase, subunit chli
C3F22_15825	COG0347	Belongs to the P(II) protein family
C3F22_15830	COG0004	ammonium transporteR
C3F22_15840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3F22_15840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3F22_15855	COG0586	Pfam SNARE associated Golgi protein
C3F22_15875	COG0795	lipopolysaccharide-transporting ATPase activity
C3F22_15880	COG0795	lipopolysaccharide-transporting ATPase activity
C3F22_15885	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C3F22_15890	COG0793	Belongs to the peptidase S41A family
C3F22_15905	COG2197	response regulator
C3F22_15910	COG1686	Belongs to the peptidase S11 family
C3F22_15915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C3F22_15925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3F22_15930	COG4974	Belongs to the 'phage' integrase family
C3F22_15955	COG0772	Belongs to the SEDS family
C3F22_15965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C3F22_15970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3F22_15975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C3F22_15980	COG0494	nUDIX hydrolase
C3F22_15995	COG1538	Outer membrane efflux protein
C3F22_16035	COG0675	Transposase, IS605 OrfB family
C3F22_16045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C3F22_16070	COG0497	DNA recombination
C3F22_16085	COG3328	transposase activity
C3F22_16115	COG1252	NADH dehydrogenase
C3F22_16120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C3F22_16145	COG4372	Transposase
C3F22_16195	COG1063	alcohol dehydrogenase
C3F22_16260	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_16270	COG1373	ATPase (AAA superfamily
C3F22_16290	COG1475	DNA binding
C3F22_16295	COG1192	Involved in chromosome partitioning
C3F22_16340	COG3188	usher protein
C3F22_16440	COG2963	transposase activity
C3F22_16450	COG4372	Transposase
C3F22_16490	COG1846	Transcriptional regulator
C3F22_16495	COG1764	response to oxidative stress
C3F22_16505	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C3F22_16510	COG3706	GGDEF domain
C3F22_16540	COG1192	Involved in chromosome partitioning
C3F22_16600	COG0739	heme binding
C3F22_16600	COG0741	lytic transglycosylase activity
C3F22_16600	COG1196	nuclear chromosome segregation
C3F22_16615	COG1196	nuclear chromosome segregation
C3F22_16615	COG0741	lytic transglycosylase activity
C3F22_16615	COG0739	heme binding
C3F22_16640	COG1525	nuclease
C3F22_16670	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_16700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3F22_16765	COG4106	trans-aconitate 2-methyltransferase activity
C3F22_16810	COG1215	transferase activity, transferring glycosyl groups
C3F22_16825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3F22_16870	COG4774	siderophore transport
C3F22_16885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C3F22_16925	COG1454	alcohol dehydrogenase
C3F22_16945	COG4372	Transposase
C3F22_16955	COG2963	transposase activity
C3F22_16965	COG4774	siderophore transport
C3F22_17025	COG1192	Involved in chromosome partitioning
C3F22_17060	COG1346	cytolysis
C3F22_17065	COG1380	Effector of murein hydrolase LrgA
C3F22_17070	COG0583	DNA-binding transcription factor activity
C3F22_17075	COG1309	transcriptional regulator
C3F22_17080	COG0604	alcohol dehydrogenase
C3F22_17110	COG2826	transposase and inactivated derivatives, IS30 family
C3F22_17150	COG4372	Transposase
C3F22_17170	COG3706	GGDEF domain
C3F22_17180	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
C3F22_17190	COG3316	Transposase and inactivated derivatives
C3F22_17240	COG2072	flavoprotein involved in K transport
C3F22_17245	COG0431	NADPH-dependent FMN reductase
C3F22_17250	COG0798	PFAM Bile acid sodium symporter
C3F22_17260	COG0640	Transcriptional regulator
C3F22_17345	COG3174	membrane
C3F22_17350	COG2205	protein histidine kinase activity
C3F22_17365	COG2132	Multicopper oxidase
C3F22_17385	COG0431	NADPH-dependent FMN reductase
C3F22_17390	COG3316	Transposase and inactivated derivatives
C3F22_17400	COG3316	Transposase and inactivated derivatives
C3F22_17415	COG2963	transposase activity
C3F22_17425	COG4372	Transposase
C3F22_17490	COG4372	Transposase
C3F22_17505	COG4372	Transposase
C3F22_17525	COG1373	ATPase (AAA superfamily
C3F22_17555	COG2009	succinate dehydrogenase
C3F22_17575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C3F22_17585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C3F22_17625	COG0625	glutathione transferase activity
C3F22_17630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_17655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3F22_17695	COG3706	GGDEF domain
C3F22_17700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_17705	COG0183	Belongs to the thiolase family
C3F22_17720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_17725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C3F22_17730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3F22_17765	COG0475	glutathione-regulated potassium exporter activity
C3F22_17765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3F22_17780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C3F22_17790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3F22_17795	COG0022	dehydrogenase e1 component
C3F22_17800	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3F22_17825	COG1063	alcohol dehydrogenase
C3F22_17830	COG1802	Transcriptional regulator
C3F22_17865	COG1120	ATPase activity
C3F22_17895	COG0642	Histidine kinase
C3F22_17900	COG0745	RESPONSE REGULATOR receiver
C3F22_17905	COG2194	sulfuric ester hydrolase activity
C3F22_17915	COG0583	DNA-binding transcription factor activity
C3F22_17920	COG0730	response to heat
C3F22_17925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3F22_17930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C3F22_17965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3F22_18025	COG1028	Short-chain dehydrogenase reductase Sdr
C3F22_18050	COG0579	oxidoreductase
C3F22_18080	COG2130	NADP-dependent
C3F22_18085	COG1309	transcriptional regulator
C3F22_18095	COG1902	pentaerythritol trinitrate reductase activity
C3F22_18105	COG1979	alcohol dehydrogenase
C3F22_18130	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C3F22_18145	COG3321	synthase
C3F22_18145	COG0604	alcohol dehydrogenase
C3F22_18150	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C3F22_18155	COG0583	DNA-binding transcription factor activity
C3F22_18160	COG4221	oxidoreductase activity
C3F22_18225	COG0659	secondary active sulfate transmembrane transporter activity