locus-tag class description C3F34_00005 ENOG4107HP6 Transcriptional regulator C3F34_00010 ENOG4105D5Q Arginine ornithine antiporter C3F34_00015 ENOG4105C3R Methionine synthase C3F34_00055 ENOG4105MRR Transcriptional regulator (By similarity) C3F34_00060 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase C3F34_00075 ENOG4105BZU Histidine kinase C3F34_00080 ENOG4108SC4 )-transporter C3F34_00090 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) C3F34_00120 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) C3F34_00125 ENOG4105DC1 bifunctional purine biosynthesis protein purh C3F34_00130 ENOG4105C12 Phosphoribosylglycinamide synthetase C3F34_00140 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase C3F34_00150 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) C3F34_00155 ENOG4108UMI ABC transporter, permease C3F34_00165 ENOG4105C0B DNA polymerase III (alpha subunit) C3F34_00175 ENOG4105D7W serine acetyltransferase C3F34_00190 ENOG4105CHR reductase C3F34_00195 ENOG41061ZR Transcriptional regulator C3F34_00205 ENOG4105CEY Amp-dependent synthetase and ligase C3F34_00225 ENOG4105C94 Transporter C3F34_00230 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) C3F34_00235 ENOG4105C26 Dehydrogenase C3F34_00250 ENOG4105DWT malate dehydrogenase (quinone) C3F34_00295 ENOG4105C26 Dehydrogenase C3F34_00300 ENOG4105E5D amino acid C3F34_00305 ENOG4105CUB amino acid C3F34_00310 ENOG4105CJP fad dependent oxidoreductase C3F34_00325 ENOG4105M6W Crispr-associated protein, Csy3 family C3F34_00335 ENOG4105ENG CRISPR-associated protein, Csy1 family C3F34_00350 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase C3F34_00365 ENOG4108RXX maleylacetoacetate isomerase C3F34_00370 ENOG4107T8P acyl-Coa dehydrogenase C3F34_00385 ENOG4105D01 (LipO)protein C3F34_00390 ENOG4105D01 (LipO)protein C3F34_00395 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) C3F34_00400 ENOG4108UMI ABC transporter, permease C3F34_00405 ENOG4105C3G gtp-binding protein C3F34_00410 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) C3F34_00430 ENOG4108UMN azlc family C3F34_00435 ENOG4105ZED uncharacterized protein ygaH C3F34_00440 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR C3F34_00460 ENOG4108NIW Leucine export protein LeuE C3F34_00465 ENOG4106AXJ AraC family transcriptional regulator C3F34_00470 ENOG4108V06 Glutathione peroxidase C3F34_00475 ENOG4105E0X reductase C3F34_00480 ENOG4105CHM Aminotransferase C3F34_00525 ENOG4107TIF Phenazine biosynthesis protein, PhzF family C3F34_00530 ENOG4108ETY sodium dicarboxylate symporter C3F34_00535 ENOG4108MEJ flavin reductase domain protein C3F34_00565 ENOG4108R99 pseudouridine synthase C3F34_00610 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) C3F34_00635 ENOG4105E9K Isocitrate dehydrogenase C3F34_00640 ENOG4108ZJI phenylacetic acid degradation protein C3F34_00645 ENOG4105VT2 5-hydroxyisourate hydrolase C3F34_00655 ENOG4105DZ1 carboxypeptidase C3F34_00665 ENOG4108YZY peptidylprolyl cis-trans isomerase C3F34_00670 ENOG4105CVP deoxyribo-dipyrimidine photolyase C3F34_00695 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase C3F34_00700 ENOG4105CQC Prephenate dehydratase C3F34_00705 ENOG4107R7Y intracellular protease Pfpi family C3F34_00710 ENOG4105C1G acyl-Coa dehydrogenase C3F34_00715 ENOG4105CK2 sodium dicarboxylate symporter C3F34_00725 ENOG4105VUT cytoplasmic protein C3F34_00730 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) C3F34_00735 ENOG4105BZ4 penicillin-binding protein C3F34_00755 ENOG4105DHQ Histidine kinase C3F34_00760 ENOG4105XJC Two component transcriptional regulator (Winged helix family C3F34_00780 ENOG4107QHF type ii secretion system protein e C3F34_00790 ENOG410620I Diguanylate cyclase C3F34_00795 ENOG4108R96 Methyltransferase, YaeB family C3F34_00800 ENOG4105DP0 ferredoxin-NADP reductase C3F34_00830 ENOG4105W1Y Transcriptional regulator C3F34_00835 ENOG4105CFP Peptidase U32 C3F34_00840 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding C3F34_00845 ENOG4108JU3 Alkyl hydroperoxide reductase C3F34_00875 ENOG4105CQ7 ATP-dependent helicase C3F34_00880 ENOG4105D3R alkyl hydroperoxide reductase C3F34_00920 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) C3F34_00925 ENOG4105D3G Pseudouridine synthase C3F34_00940 ENOG4107S5G Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) C3F34_00945 ENOG4105NXH GreA GreB family elongation factor C3F34_00975 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) C3F34_00995 ENOG4105CEB Aspartate aminotransferase C3F34_01010 ENOG4105D2S major facilitator superfamily C3F34_01015 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) C3F34_01055 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) C3F34_01060 ENOG41076HS cation diffusion facilitator family transporter C3F34_01065 ENOG4105CPW cytochrome b561 C3F34_01070 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) C3F34_01090 ENOG4105E09 nadh pyrophosphatase C3F34_01110 ENOG4105DA5 (ABC) transporter C3F34_01115 ENOG4105E3A (ABC) transporter C3F34_01130 ENOG4105CNI cell division protein FtsW C3F34_01135 ENOG4105CVE Lytic murein transglycosylase C3F34_01145 ENOG4105EFZ amidohydrolase C3F34_01190 ENOG4105CE9 30S ribosomal protein S2 C3F34_01195 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) C3F34_01205 ENOG4107RNU major facilitator superfamily MFS_1 C3F34_01220 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) C3F34_01225 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) C3F34_01245 ENOG4105DTD Dehydrogenase C3F34_01250 ENOG4105CY2 Citrate transporter C3F34_01255 ENOG4108M0I Transcriptional regulator C3F34_01265 ENOG4107QNJ CoA-transferase subunit B C3F34_01270 ENOG4105CHU acetyl-coa acetyltransferase C3F34_01285 ENOG4108ETH Formylglycinamide ribotide synthetase C3F34_01300 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) C3F34_01455 ENOG4105EFC phage portal protein HK97 family C3F34_01460 ENOG4105CAR Terminase, large subunit C3F34_01520 ENOG4105MEW serine threonine protein phosphatase C3F34_01595 ENOG4105H40 C3F34_01645 ENOG4107YD3 Thioesterase C3F34_01650 ENOG4105E02 MotA TolQ exbB proton channel C3F34_01655 ENOG4105M8F Biopolymer transport protein exbD tolR C3F34_01665 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) C3F34_01670 ENOG4105KCK Peptidoglycan-associated lipoprotein C3F34_01730 ENOG4105C02 permease C3F34_01740 ENOG4108V3E phosphoribosylglycinamide formyltransferase C3F34_01760 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 C3F34_01765 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) C3F34_01770 ENOG4105D60 lipoprotein releasing system transmembrane protein C3F34_01785 ENOG4108UPT UPF0178 protein C3F34_01805 ENOG4107KET secretion protein, HlyD family C3F34_01825 ENOG4105CK2 sodium dicarboxylate symporter C3F34_01835 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) C3F34_01840 ENOG4105C10 Electron transfer flavoprotein C3F34_01845 ENOG4105BZJ Electron transfer flavoprotein C3F34_01850 ENOG4105N14 lysine exporter protein LysE YggA C3F34_01855 ENOG4108YXU transcriptional regulator AsnC family C3F34_01860 ENOG4108YYQ gCN5-related N-acetyltransferase C3F34_01870 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) C3F34_01885 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) C3F34_01895 ENOG4105C85 amino acid C3F34_01900 ENOG4105BZG amino acid carrier protein C3F34_01905 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) C3F34_01920 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) C3F34_01925 ENOG4105C11 sulfate adenylyltransferase), subunit 2 C3F34_01940 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) C3F34_01955 ENOG4105C5F glutamine synthetase C3F34_01965 ENOG4105RPH Inner membrane protein YddG C3F34_01990 ENOG4108I0Z Aconitate hydratase C3F34_01995 ENOG4105BZN citrate synthase C3F34_02000 ENOG4105CR4 methylisocitrate lyase C3F34_02005 ENOG4105DRR Transcriptional regulator, GntR family C3F34_02010 ENOG4105C59 p-type ATPase C3F34_02020 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase C3F34_02035 ENOG4107VAM peptidase, m28 C3F34_02045 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b C3F34_02055 ENOG4105D82 Glutamate dehydrogenase C3F34_02060 ENOG4108R3D Electron transport complex C3F34_02105 ENOG4106H78 methyltransferase C3F34_02135 ENOG4108W5M transcriptional regulator C3F34_02140 ENOG4105CZM Major Facilitator C3F34_02145 ENOG4105YIP Tetr family transcriptional regulator C3F34_02155 ENOG4105D78 K07001 NTE family protein C3F34_02160 ENOG4105BZG amino acid carrier protein C3F34_02165 ENOG4105D6U Sodium Glutamate Symporter C3F34_02180 ENOG4105CGZ zinc metallopeptidase C3F34_02185 ENOG4105CKW Inner membrane protein yedI C3F34_02195 ENOG4105PV3 Inner membrane protein yqiJ C3F34_02200 ENOG4107S78 Band 7 protein C3F34_02220 ENOG4105F11 amine oxidase C3F34_02230 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha C3F34_02240 ENOG4107QN2 dihydrolipoyl dehydrogenase C3F34_02245 ENOG4105C7S Dehydrogenase C3F34_02250 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 C3F34_02255 ENOG4105E33 succinate dehydrogenase C3F34_02265 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein C3F34_02270 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit C3F34_02280 ENOG4105F95 Monooxygenase C3F34_02300 ENOG4105C4K Nad synthetase C3F34_02320 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding C3F34_02340 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase C3F34_02345 ENOG4105C34 Pseudouridine synthase C3F34_02350 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane C3F34_02355 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) C3F34_02370 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) C3F34_02400 ENOG4105C5T Phosphoribosyl pyrophosphate synthase C3F34_02420 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) C3F34_02425 ENOG4108NIW Leucine export protein LeuE C3F34_02450 ENOG4107T5V SNARE associated Golgi C3F34_02460 ENOG4105ETT transcriptional Regulator, LysR family C3F34_02485 ENOG4108Z43 UPF0250 protein C3F34_02490 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) C3F34_02505 ENOG4105CUB amino acid C3F34_02515 ENOG4107EXU Short-chain dehydrogenase reductase Sdr C3F34_02525 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) C3F34_02530 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) C3F34_02535 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) C3F34_02545 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) C3F34_02555 ENOG4105K46 50S ribosomal protein l27 C3F34_02575 ENOG410841Q phosphoesterase PA-phosphatase related protein C3F34_02580 ENOG4105C1P efflux transporter, rnd family, mfp subunit C3F34_02585 ENOG4105BZS acriflavin resistance protein C3F34_02590 ENOG4105ENJ RND efflux system, outer membrane lipoprotein C3F34_02595 ENOG4105K8R UPF0145 protein C3F34_02610 ENOG4105CHR reductase C3F34_02620 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) C3F34_02665 ENOG4105EAD ABC transporter C3F34_02670 ENOG4105DRP amino acid AbC transporter C3F34_02675 ENOG4105CDA abc transporter atp-binding protein C3F34_02685 ENOG4105PAD Hydrolase C3F34_02695 ENOG4105DHQ Histidine kinase C3F34_02700 ENOG4105XJC Two component transcriptional regulator (Winged helix family C3F34_02705 ENOG4105DIJ Phosphoethanolamine transferase C3F34_02720 ENOG4105EYM Major Facilitator superfamily C3F34_02730 ENOG4105D78 K07001 NTE family protein C3F34_02750 ENOG4105CK7 Sodium proline symporter C3F34_02755 ENOG4105CTB Polyprenyl synthetase C3F34_02760 ENOG4105BZU Histidine kinase C3F34_02765 ENOG4105C7F AcnD-accessory protein PrpF C3F34_02770 ENOG4105C85 amino acid C3F34_02790 ENOG4105EEX Two component transcriptional regulator (Winged helix family C3F34_02795 ENOG4105C08 Histidine kinase C3F34_02800 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) C3F34_02805 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) C3F34_02810 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) C3F34_02830 ENOG4105CY0 Metallo-Beta-Lactamase C3F34_02865 ENOG4105K6H D-cysteine desulfhydrase C3F34_02870 ENOG4105CBX hi0933 family C3F34_02885 ENOG4105CPD ethanolamine ammonia-lyase C3F34_02890 ENOG4107R55 ethanolamine transporter C3F34_02900 ENOG4105DP0 ferredoxin-NADP reductase C3F34_02905 ENOG4105DUM transcriptional regulator, lysR family C3F34_02910 ENOG4105VEQ Cold shock protein C3F34_02930 ENOG4105C8S subunit m C3F34_02935 ENOG4105D65 subunit l C3F34_02940 ENOG41080EA NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) C3F34_02945 ENOG4107UFS subunit j C3F34_02950 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) C3F34_02960 ENOG4108IEH NADH dehydrogenase subunit g C3F34_02965 ENOG4107QIZ NADH dehydrogenase C3F34_02970 ENOG4105GKE subunit e C3F34_02975 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) C3F34_02995 ENOG4105JJR Histidine kinase C3F34_03000 ENOG4107EXC regulatoR C3F34_03005 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) C3F34_03015 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) C3F34_03025 ENOG4105UYK outer membrane protein a C3F34_03035 ENOG4108JJA ABC, transporter C3F34_03050 ENOG4105CHR reductase C3F34_03055 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase C3F34_03060 ENOG4105VGS 50s ribosomal protein l32 C3F34_03065 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein C3F34_03070 ENOG4108BPE -transporting atpase C3F34_03075 ENOG4107RTD sua5 ycio yrdc ywlc family protein C3F34_03080 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) C3F34_03085 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) C3F34_03090 ENOG4105FE9 pseudouridine synthase C3F34_03095 ENOG4108JQ6 ABC transporter C3F34_03100 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component C3F34_03110 ENOG4105DGW oligopeptidase A C3F34_03120 ENOG4107QSI ABC, transporter C3F34_03145 ENOG4105SG9 biopolymer transport protein, ExbD C3F34_03160 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) C3F34_03165 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) C3F34_03170 ENOG4105C8Y Acetylornithine aminotransferase C3F34_03175 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) C3F34_03180 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen C3F34_03190 ENOG4108UWD Iron-storage protein C3F34_03195 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase C3F34_03200 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) C3F34_03210 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) C3F34_03220 ENOG4105HF0 Membrane C3F34_03225 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase C3F34_03240 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY C3F34_03275 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) C3F34_03285 ENOG4105KWI UPF0339 protein C3F34_03295 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA C3F34_03305 ENOG4105K78 MarR family Transcriptional regulator C3F34_03325 ENOG4105D3G Pseudouridine synthase C3F34_03360 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) C3F34_03375 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein C3F34_03385 ENOG4105D8T Acyltransferase C3F34_03390 ENOG4105C03 ribonuclease C3F34_03395 ENOG4108Z03 MAF-like protein C3F34_03400 ENOG4105VQ7 Rod shape-determining protein MreD C3F34_03405 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) C3F34_03410 ENOG4105DFF Rod shape-determining protein mreb C3F34_03415 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) C3F34_03425 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) C3F34_03445 ENOG4108KB2 LysR family Transcriptional regulator C3F34_03495 ENOG4108N2Y auxin Efflux C3F34_03500 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase C3F34_03510 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) C3F34_03520 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) C3F34_03530 ENOG4105C2W permease C3F34_03535 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) C3F34_03540 ENOG4108IQI permease C3F34_03545 ENOG4105DFA alanine racemase domain protein C3F34_03550 ENOG4105CZX twitching motility protein C3F34_03555 ENOG4105CZX twitching motility protein C3F34_03560 ENOG4108WHA ompa motb domain protein C3F34_03570 ENOG4105CHU acetyl-coa acetyltransferase C3F34_03590 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) C3F34_03595 ENOG4105DZG Dehydrogenase C3F34_03600 ENOG4105TW1 Carbohydrate-selective porin OprB C3F34_03610 ENOG4108R6W Transcriptional regulator, ARAC family C3F34_03625 ENOG4105CHU acetyl-coa acetyltransferase C3F34_03655 ENOG4108UT2 hemolysin iii C3F34_03660 ENOG4105CSH Transporter C3F34_03665 ENOG4105DIN metallophosphoesterase C3F34_03670 ENOG4107RZC phospholipase d C3F34_03680 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) C3F34_03705 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) C3F34_03710 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) C3F34_03715 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) C3F34_03720 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) C3F34_03725 ENOG4108UJD 30S ribosomal protein S9 C3F34_03730 ENOG4107MKT Stringent starvation protein a C3F34_03735 ENOG4105KB2 stringent starvation protein b C3F34_03795 ENOG4108KHX Diguanylate cyclase C3F34_03825 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) C3F34_03830 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) C3F34_03845 ENOG4105D3R alkyl hydroperoxide reductase C3F34_03865 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase C3F34_03870 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) C3F34_03905 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) C3F34_03915 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) C3F34_03920 ENOG4108WBT adenosyltransferase C3F34_03940 ENOG4105CNG UPF0061 protein C3F34_03945 ENOG4105MSB protein, conserved in bacteria C3F34_03950 ENOG4105C85 amino acid C3F34_03955 ENOG4105E3W Two component transcriptional regulator (Winged helix family C3F34_03960 ENOG4105EB3 Histidine kinase C3F34_03970 ENOG4105CSU acyl-Coa dehydrogenase C3F34_03975 ENOG4105CSU acyl-Coa dehydrogenase C3F34_03980 ENOG4108VY7 phosphate-starvation-inducible protein PsiE C3F34_04000 ENOG4105UGU tonB-dependent Receptor C3F34_04010 ENOG4105C9M aspartyl-trna synthetase C3F34_04035 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase C3F34_04045 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase C3F34_04050 ENOG4105C1B dTDP-glucose 4-6-dehydratase C3F34_04065 ENOG4107BJW polysaccharide deacetylase C3F34_04075 ENOG4105CM2 brancheD-chain amino acid aminotransferase C3F34_04080 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) C3F34_04085 ENOG4105BZU Histidine kinase C3F34_04090 ENOG4105BZU Histidine kinase C3F34_04095 ENOG4105BZU Histidine kinase C3F34_04100 ENOG4105CN1 protease C3F34_04130 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) C3F34_04135 ENOG4108DNC Involved in acetate metabolism (By similarity) C3F34_04145 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) C3F34_04150 ENOG4105DWP Membrane C3F34_04160 ENOG4107GFK fumarate C3F34_04180 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) C3F34_04190 ENOG4105D05 Receptor C3F34_04195 ENOG4108ESX Receptor C3F34_04205 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) C3F34_04215 ENOG4105DWV Homoserine O-trans-acetylase C3F34_04325 ENOG4105CIY formyltetrahydrofolate deformylase C3F34_04330 ENOG41062JF Transcriptional regulator C3F34_04335 ENOG4107RGH Aldehyde dehydrogenase C3F34_04340 ENOG4105KDC 50s ribosomal protein l28 C3F34_04345 ENOG4105W0E 50S ribosomal protein L33 C3F34_04350 ENOG4105CKD glutathione-regulated potassium-efflux system protein C3F34_04370 ENOG4105VFU Rna-binding protein C3F34_04380 ENOG4105BZW Glycerate kinase C3F34_04400 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) C3F34_04420 ENOG4105C5H ABC transporter C3F34_04435 ENOG4105D1S lipid A biosynthesis C3F34_04470 ENOG4105HDK L-asparaginase C3F34_04495 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) C3F34_04520 ENOG4105DUM transcriptional regulator, lysR family C3F34_04545 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase C3F34_04555 ENOG4105K56 Transcriptional regulator C3F34_04565 ENOG4105CSU acyl-Coa dehydrogenase C3F34_04575 ENOG4108NIW Leucine export protein LeuE C3F34_04580 ENOG4105EXG Transcriptional regulator C3F34_04585 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) C3F34_04590 ENOG4105KIR Thiol-disulfide oxidoreductase dcc C3F34_04605 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase C3F34_04610 ENOG4105MI0 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity) C3F34_04615 ENOG4108QJ2 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase C3F34_04625 ENOG4108SBK dioxygenase, subunit beta C3F34_04630 ENOG4105FUY alpha subunit C3F34_04635 ENOG4108W5M transcriptional regulator C3F34_04650 ENOG4105EPF Outer membrane porin C3F34_04655 ENOG4105DF3 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity) C3F34_04660 ENOG4105DIV Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity) C3F34_04665 ENOG4105IKQ hydratase C3F34_04680 ENOG4105D29 Helix-turn-helix type 11 domain protein C3F34_04685 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) C3F34_04690 ENOG4105EI2 Pseudouridine synthase C3F34_04700 ENOG4105C03 ribonuclease C3F34_04705 ENOG4105J5T Amp-dependent synthetase and ligase C3F34_04730 ENOG41067S9 phage shock protein C, PspC C3F34_04750 ENOG4105C38 Glycyl-tRNA synthetase beta subunit C3F34_04775 ENOG4105C5I Dehydrogenase C3F34_04800 ENOG4105BZ8 glutamate synthase C3F34_04820 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) C3F34_04835 ENOG4105C5X domain protein C3F34_04850 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) C3F34_04860 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase C3F34_04875 ENOG4108JU5 Magnesium and cobalt efflux protein C3F34_04880 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) C3F34_04890 ENOG4108VAU general secretion pathway protein G C3F34_04895 ENOG4105D7Q type ii secretion system C3F34_04900 ENOG4105C25 Primosomal protein n' C3F34_04910 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) C3F34_04920 ENOG4105DVC DnaJ domain protein C3F34_04925 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) C3F34_04930 ENOG4105Z2P Protein of unknown function (DUF465) C3F34_04935 ENOG4105D7N magnesium and cobalt transport protein CorA C3F34_04945 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) C3F34_04950 ENOG4107QYX exodeoxyribonuclease v alpha C3F34_04955 ENOG4107QKA exodeoxyribonuclease V beta C3F34_04960 ENOG4105DSY exodeoxyribonuclease V, gamma C3F34_04970 ENOG4105CSR polyphosphate kinase 2 C3F34_04980 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) C3F34_04990 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) C3F34_05000 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase C3F34_05020 ENOG4105D65 subunit l C3F34_05025 ENOG4108ZE9 Monovalent cation H antiporter subunit C C3F34_05030 ENOG4107R4Z monovalent cation h antiporter subunit d C3F34_05035 ENOG4105SC1 monovalent cation H antiporter subunit E C3F34_05040 ENOG4105W4C monovalent cation H antiporter subunit F C3F34_05045 ENOG4105KJM monovalent cation h antiporter subunit g C3F34_05050 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) C3F34_05055 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) C3F34_05060 ENOG4105CHV Transcription elongation factor NusA C3F34_05065 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) C3F34_05090 ENOG4107EJC Preprotein translocase subunit SecG C3F34_05100 ENOG4107QHF type ii secretion system protein e C3F34_05115 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) C3F34_05125 ENOG4105C2N RNA methyltransferase TrmH family group 3 C3F34_05130 ENOG4105NBK UPF0345 protein C3F34_05135 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) C3F34_05145 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) C3F34_05160 ENOG4107Z11 Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity) C3F34_05170 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase C3F34_05185 ENOG4105KVH Transcriptional regulator C3F34_05240 ENOG4107ZXU DSBA oxidoreductase C3F34_05270 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) C3F34_05285 ENOG4105D3Y Na H antiporter C3F34_05330 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) C3F34_05340 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) C3F34_05345 ENOG4105PM1 preprotein translocase subunit SecE C3F34_05355 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) C3F34_05385 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) C3F34_05390 ENOG4105TV9 FHA Domain-Containing protein C3F34_05395 ENOG4105GVR general secretion pathway protein D C3F34_05410 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS C3F34_05435 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) C3F34_05440 ENOG4108NEV two component transcriptional regulator, LytTR family C3F34_05445 ENOG4108HRK Histidine kinase C3F34_05460 ENOG4108UTW Plays a role in the regulation of phosphate uptake C3F34_05465 ENOG4105DFG type I secretion outer membrane protein C3F34_05480 ENOG41087AY ADP-Ribose pyrophosphatase C3F34_05490 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters C3F34_05495 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) C3F34_05500 ENOG4105CNI cell division protein FtsW C3F34_05515 ENOG4105CE1 Ferrous iron transport protein b C3F34_05525 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) C3F34_05530 ENOG4105T95 Thiol disulfide interChange protein C3F34_05535 ENOG4105D6E homoserine dehydrogenase C3F34_05555 ENOG41061WM D-Alanyl-D-Alanine C3F34_05565 ENOG4105BZU Histidine kinase C3F34_05570 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family C3F34_05575 ENOG4105CN1 protease C3F34_05580 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) C3F34_05585 ENOG4108K5H permease YjgP YjgQ family protein C3F34_05590 ENOG4108M8S permease YjgP YjgQ family protein C3F34_05615 ENOG4105DQR SNARE associated Golgi C3F34_05630 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) C3F34_05640 ENOG4105BZU Histidine kinase C3F34_05655 ENOG4105C0P Mg chelatase subunit ChlI C3F34_05665 ENOG4105EPF Outer membrane porin C3F34_05670 ENOG4105F0N pyrophosphate phospho-hydrolase C3F34_05685 ENOG4105CEY Amp-dependent synthetase and ligase C3F34_05690 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) C3F34_05695 ENOG41079KZ Major Facilitator Superfamily C3F34_05700 ENOG4105EN6 Membrane C3F34_05710 ENOG4105EE5 Membrane protein terC C3F34_05715 ENOG4108URH decarboxylase C3F34_05725 ENOG4105C0R drug resistance transporter emrb qaca subfamily C3F34_05735 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) C3F34_05750 ENOG4105CCT upf0313 protein C3F34_05755 ENOG4105D2S major facilitator superfamily C3F34_05810 ENOG4108WZM domain protein C3F34_05815 ENOG4105C79 DNA protecting protein DprA C3F34_05835 ENOG4108V06 Glutathione peroxidase C3F34_05865 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) C3F34_05875 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) C3F34_05890 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) C3F34_05915 ENOG4105FDK ABC transporter C3F34_05920 ENOG4105FAV ABC, transporter C3F34_05925 ENOG410829K Lysine exporter protein (Lyse ygga) C3F34_05930 ENOG4105EZR dyp-type peroxidase family protein C3F34_05965 ENOG4107R1I NAD-dependent malic enzyme C3F34_05995 ENOG4105EUB pirin domain protein C3F34_06000 ENOG4105BZU Histidine kinase C3F34_06020 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) C3F34_06025 ENOG4108VBZ doxx family C3F34_06030 ENOG4105DQR SNARE associated Golgi C3F34_06045 ENOG4107QJE Chromosome Partitioning Protein C3F34_06055 ENOG4107PSF BolA-like protein C3F34_06090 ENOG4105ZTP Protein of unknown function (DUF1376) C3F34_06125 ENOG4105CMI transporter C3F34_06130 ENOG4105CJ1 ABC, transporter C3F34_06135 ENOG4105D0S secretion protein (HlyD C3F34_06170 ENOG4105CSR polyphosphate kinase 2 C3F34_06230 ENOG4105C85 amino acid C3F34_06240 ENOG4105EY2 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity) C3F34_06245 ENOG4105C26 Dehydrogenase C3F34_06260 ENOG4105D82 Glutamate dehydrogenase C3F34_06270 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) C3F34_06275 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) C3F34_06280 ENOG4107YIM Involved in the transcription termination process (By similarity) C3F34_06285 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) C3F34_06290 ENOG4108ZAI phosphatidylglycerophosphatase a C3F34_06300 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) C3F34_06330 ENOG4107QKV phosphomannomutase C3F34_06335 ENOG4105CMR udp-glucose 4-epimerase C3F34_06340 ENOG4107QP8 phosphohexose isomerase C3F34_06345 ENOG4105C6Y Udp-glucose 6-dehydrogenase C3F34_06350 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase C3F34_06355 ENOG4105D3Q Sugar transferase C3F34_06360 ENOG4108RYC glycosyltransferase C3F34_06365 ENOG4105CG5 Glycosyl transferase (Group 1 C3F34_06375 ENOG4105P7J Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D- glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide C3F34_06380 ENOG4108MY6 biosynthesis protein C3F34_06400 ENOG4105F0R Cytidylyltransferase C3F34_06405 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase C3F34_06410 ENOG4105C5E polysaccharide biosynthesis protein C3F34_06415 ENOG4107QQG Dehydrogenase C3F34_06430 ENOG4105D75 Capsular exopolysaccharide family C3F34_06435 ENOG4108V1T peptidylprolyl cis-trans isomerase C3F34_06440 ENOG4108V1T peptidylprolyl cis-trans isomerase C3F34_06445 ENOG4105CJR Integral membrane protein (MviN C3F34_06455 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase C3F34_06465 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) C3F34_06480 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) C3F34_06485 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) C3F34_06490 ENOG4105UBK short-chain dehydrogenase reductase C3F34_06505 ENOG4107QZM n-acetylglutamate synthase C3F34_06510 ENOG4105GVF (ABC) transporter C3F34_06515 ENOG4105GVF (ABC) transporter C3F34_06520 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) C3F34_06525 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component C3F34_06530 ENOG4108VM9 ABC, transporter C3F34_06535 ENOG4108R86 Transcriptional regulator C3F34_06540 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) C3F34_06560 ENOG4105DTN riboflavin biosynthesis protein ribF C3F34_06565 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) C3F34_06575 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase C3F34_06595 ENOG4105C01 Dihydroxy-acid dehydratase C3F34_06610 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B C3F34_06615 ENOG4105DUN Mediates zinc uptake. May also transport other divalent cations (By similarity) C3F34_06625 ENOG4105C8J )-transporter C3F34_06680 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) C3F34_06700 ENOG4105DDW LysR family Transcriptional regulator C3F34_06725 ENOG4105CVE Lytic murein transglycosylase C3F34_06730 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit C3F34_06735 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) C3F34_06745 ENOG4105DFU Cell wall formation (By similarity) C3F34_06760 ENOG4105DU1 integral membrane protein, terc C3F34_06765 ENOG4107QUY Guanine deaminase C3F34_06770 ENOG4108UGV hypoxanthine phosphoribosyltransferase C3F34_06780 ENOG4105T95 Thiol disulfide interChange protein C3F34_06785 ENOG4105PGM cation diffusion facilitator family transporter C3F34_06810 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins C3F34_06815 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) C3F34_06820 ENOG4105NVJ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) C3F34_06825 ENOG4105VG0 50S ribosomal protein l34 C3F34_06830 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) C3F34_06835 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) C3F34_06845 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) C3F34_06855 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) C3F34_06860 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) C3F34_06870 ENOG4108821 RND type efflux pump C3F34_06875 ENOG4108821 RND type efflux pump C3F34_06880 ENOG4108821 RND type efflux pump C3F34_06885 ENOG4105C5H ABC transporter C3F34_06915 ENOG4105D2S major facilitator superfamily C3F34_06935 ENOG4105C2W permease C3F34_06945 ENOG4108IG5 Transcriptional regulator C3F34_06950 ENOG4105DJY efflux transporter, rnd family, mfp subunit C3F34_06975 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) C3F34_06985 ENOG4105F27 Major Facilitator C3F34_06990 ENOG4105CV8 reductase C3F34_06995 ENOG4105HEI LysR family (Transcriptional regulator C3F34_07010 ENOG4105DQ4 alcohol dehydrogenase C3F34_07015 ENOG4108R3E Dna-3-methyladenine glycosylase i C3F34_07030 ENOG4105CEN a g-specific adenine glycosylase C3F34_07050 ENOG4108ZZ3 UPF0260 protein C3F34_07055 ENOG4105NIV Esterase C3F34_07060 ENOG4105D1H recombination factor protein RarA C3F34_07065 ENOG4108JEH abc transporter atp-binding protein C3F34_07070 ENOG4106YG3 ABC transporter C3F34_07075 ENOG4105DSP amino acid AbC transporter C3F34_07080 ENOG4105E89 ABC transporter C3F34_07090 ENOG4105F7P transcriptional regulator AsnC family C3F34_07095 ENOG4105C8V SAICAR synthetase C3F34_07105 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) C3F34_07115 ENOG4108RWI nicotinamidase C3F34_07120 ENOG4105C09 Bile acid C3F34_07135 ENOG4105EAC phosphoserine phosphatase C3F34_07170 ENOG4105KHC sulfurtransferase C3F34_07180 ENOG4105BZU Histidine kinase C3F34_07185 ENOG4105CK6 Two component transcriptional regulator (Winged helix family C3F34_07200 ENOG4107QJQ Mate efflux family protein C3F34_07205 ENOG4105CHM Aminotransferase C3F34_07210 ENOG4106BRA Membrane C3F34_07225 ENOG4105D9M gamma-glutamylcysteine synthetase C3F34_07230 ENOG41080I0 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) C3F34_07240 ENOG4105IPS esterase C3F34_07245 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) C3F34_07255 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein C3F34_07260 ENOG4105C32 Amino acid ABC transporter (Permease) C3F34_07270 ENOG4105C0Z ABC transporter C3F34_07275 ENOG4108IV0 ABC, transporter C3F34_07310 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) C3F34_07320 ENOG4105BZU Histidine kinase C3F34_07325 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) C3F34_07345 ENOG4105CGK Exodeoxyribonuclease III C3F34_07355 ENOG4105CC0 LysR family Transcriptional regulator C3F34_07360 ENOG4105CHJ isochorismatase hydrolase C3F34_07380 ENOG4105D7Z glutathione synthase C3F34_07390 ENOG4105DFU Cell wall formation (By similarity) C3F34_07400 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) C3F34_07405 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) C3F34_07410 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) C3F34_07430 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) C3F34_07435 ENOG4107QSN dihydrolipoamide acetyltransferase C3F34_07455 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) C3F34_07470 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) C3F34_07495 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase C3F34_07500 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase C3F34_07510 ENOG4105D64 Mechanosensitive ion channel C3F34_07520 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) C3F34_07530 ENOG4105FBW Monooxygenase C3F34_07535 ENOG4108UZX fmn reductase C3F34_07550 ENOG4105BZU Histidine kinase C3F34_07555 ENOG41062QD Membrane C3F34_07570 ENOG4105C94 Transporter C3F34_07585 ENOG4108HWY Beta-lactamase C3F34_07600 ENOG4105BZU Histidine kinase C3F34_07635 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) C3F34_07640 ENOG4108WUH Transcriptional regulator, TetR family C3F34_07645 ENOG4105CPQ Dehydrogenase C3F34_07655 ENOG4105RA2 Membrane C3F34_07660 ENOG4108IXY short-chain dehydrogenase reductase C3F34_07670 ENOG4105DWF phosphomethylpyrimidine kinase C3F34_07680 ENOG4107RDB Major Facilitator C3F34_07685 ENOG4108UUM single-stranded DNA-binding protein C3F34_07690 ENOG4105C85 amino acid C3F34_07700 ENOG4108JPW Aminotransferase C3F34_07705 ENOG4105C26 Dehydrogenase C3F34_07710 ENOG4105D3R alkyl hydroperoxide reductase C3F34_07715 ENOG4105JQN Transcriptional regulator C3F34_07720 ENOG4105CHJ isochorismatase hydrolase C3F34_07725 ENOG4105EUB pirin domain protein C3F34_07750 ENOG4105D94 Major Facilitator Superfamily C3F34_07755 ENOG4107RSM transcriptional regulator C3F34_07770 ENOG4105C26 Dehydrogenase C3F34_07775 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase C3F34_07785 ENOG4105C1G acyl-Coa dehydrogenase C3F34_07790 ENOG4105E39 Enoyl-CoA hydratase C3F34_07815 ENOG4105C0D helicase C3F34_07900 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) C3F34_07920 ENOG4105CUV Homoserine Kinase C3F34_07940 ENOG4105CUB amino acid C3F34_07945 ENOG4105CJP fad dependent oxidoreductase C3F34_07965 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) C3F34_07970 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) C3F34_08005 ENOG4105CYC Transferase C3F34_08010 ENOG4105E0F Histidine kinase C3F34_08015 ENOG4105DPZ Two component transcriptional regulator (Winged helix family C3F34_08020 ENOG4105BZM domain protein C3F34_08030 ENOG4105PDP Short chain dehydrogenase C3F34_08040 ENOG4105C5H ABC transporter C3F34_08105 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein C3F34_08110 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) C3F34_08120 ENOG4105CJN penicillin-binding protein C3F34_08125 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) C3F34_08130 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) C3F34_08140 ENOG4105DHI Methyltransferase C3F34_08145 ENOG4108JQC penicillin-binding protein 1A C3F34_08170 ENOG4105E4G Type IV pilus C3F34_08190 ENOG4105CBC glutamate synthase C3F34_08195 ENOG4105BZ8 glutamate synthase C3F34_08205 ENOG4108V0P LemA family C3F34_08210 ENOG4105HA9 of methanol dehydrogenase type C3F34_08220 ENOG4105KHS type IV fimbrial pilin protein C3F34_08225 ENOG4105KHS type IV fimbrial pilin protein C3F34_08230 ENOG4108YSG O-Antigen polymerase C3F34_08235 ENOG4108YSG O-Antigen polymerase C3F34_08240 ENOG4108UQY Iron-storage protein C3F34_08245 ENOG4105W53 bacterioferritin-associated ferredoxin C3F34_08250 ENOG4105KME endoribonuclease L-psp C3F34_08255 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) C3F34_08260 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) C3F34_08265 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) C3F34_08310 ENOG4105K5M 30s ribosomal protein S16 C3F34_08315 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) C3F34_08325 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) C3F34_08335 ENOG4107IFA Lipase (EC 3.1.1.3) C3F34_08340 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) C3F34_08345 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) C3F34_08365 ENOG4107AQZ Membrane C3F34_08370 ENOG4108JQ1 Dehydrogenase C3F34_08375 ENOG4105CQB FAD linked oxidase domain protein C3F34_08395 ENOG4105CSH Transporter C3F34_08400 ENOG4107QF7 multi-drug C3F34_08405 ENOG4105VCH membrane C3F34_08410 ENOG4105EM2 membrane C3F34_08415 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) C3F34_08420 ENOG4105IPI Membrane C3F34_08425 ENOG4107SKI cobyrinic Acid a,c-diamide synthase C3F34_08450 ENOG4105WMR Protein CrcB homolog C3F34_08455 ENOG4105NRA 50s ribosomal protein l31 type b C3F34_08465 ENOG4107QI1 Mate efflux family protein C3F34_08475 ENOG4105CSA Coproporphyrinogen iii oxidase C3F34_08495 ENOG4105CSU acyl-Coa dehydrogenase C3F34_08515 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) C3F34_08535 ENOG4105ECY inositol monophosphatase C3F34_08540 ENOG4105C1J atp-dependent rna helicase C3F34_08545 ENOG4105DHJ ABC, transporter C3F34_08550 ENOG4105CY3 ABC transporter, permease C3F34_08555 ENOG4107PE3 Mammalian cell entry related domain protein C3F34_08570 ENOG4107QUT magnesium and cobalt transport protein CorA C3F34_08575 ENOG4108URH decarboxylase C3F34_08585 ENOG4105MJ2 Competence protein C3F34_08590 ENOG4105CB5 ATP-dependent DNA helicase recG C3F34_08610 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) C3F34_08615 ENOG4105E55 glycerol-3-phosphate acyltransferase C3F34_08620 ENOG4105C29 acyl-CoA thioesterase C3F34_08625 ENOG4105CK2 sodium dicarboxylate symporter C3F34_08650 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) C3F34_08655 ENOG4105D7A ATP-binding protein C3F34_08660 ENOG4105C28 cystathionine C3F34_08665 ENOG41089BK Glutamine amido-transferase C3F34_08680 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) C3F34_08685 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) C3F34_08695 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) C3F34_08735 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits C3F34_08745 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) C3F34_08750 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) C3F34_08760 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) C3F34_08775 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) C3F34_08780 ENOG41067V7 50S ribosomal protein L36 C3F34_08785 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits C3F34_08790 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) C3F34_08795 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) C3F34_08805 ENOG4108ZT0 50S ribosomal protein l17 C3F34_08810 ENOG4105CT3 Monooxygenase C3F34_08815 ENOG4105C1G acyl-Coa dehydrogenase C3F34_08845 ENOG4105EMK carboxylate amino acid amine transporter C3F34_08860 ENOG4105DGW oligopeptidase A C3F34_08870 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) C3F34_08905 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase C3F34_08935 ENOG4107S2Z UPF0761 membrane protein C3F34_08945 ENOG4105CS1 NAD(P)H quinone oxidoreductase C3F34_08955 ENOG4105BZU Histidine kinase C3F34_08985 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) C3F34_08990 ENOG4105C9A Phoh family C3F34_09000 ENOG4105E4C Lytic transglycosylase catalytic C3F34_09035 ENOG4105D6S protein involved in catabolism of external DNA C3F34_09040 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase C3F34_09095 ENOG4107QPB Beta-lactamase domain protein C3F34_09110 ENOG4105NAU thioesterase Superfamily protein C3F34_09120 ENOG4108VPT UPF0234 protein C3F34_09140 ENOG4105K9H YciI-like protein C3F34_09155 ENOG4107MKT Stringent starvation protein a C3F34_09160 ENOG4105FFC UPF0187 protein C3F34_09165 ENOG4105W5Q DNA repair protein (RadC C3F34_09170 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase C3F34_09175 ENOG4108XVM Cytochrome b(562) C3F34_09195 ENOG4105VW4 glutaredoxin 3 C3F34_09205 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) C3F34_09210 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) C3F34_09220 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH C3F34_09225 ENOG4105ENJ RND efflux system, outer membrane lipoprotein C3F34_09230 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) C3F34_09235 ENOG4105DJY efflux transporter, rnd family, mfp subunit C3F34_09260 ENOG4105C7K acetolactate synthase C3F34_09265 ENOG4108ZP8 Acetolactate synthase small subunit C3F34_09305 ENOG4105WVQ Fe-S assembly protein IscX C3F34_09345 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) C3F34_09360 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) C3F34_09365 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) C3F34_09370 ENOG4105VIE preprotein translocase, subunit YajC C3F34_09385 ENOG4108V0P LemA family C3F34_09395 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) C3F34_09455 ENOG4105CGF Aromatic amino acid aminotransferase C3F34_09460 ENOG4105C85 amino acid C3F34_09470 ENOG4108RXX maleylacetoacetate isomerase C3F34_09495 ENOG4105F7P transcriptional regulator AsnC family C3F34_09500 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) C3F34_09515 ENOG4105F8V Hydrolase, tatD family C3F34_09520 ENOG4107QM5 aconitate hydratase C3F34_09530 ENOG4105CUZ uba thif-type nad fad binding protein C3F34_09540 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) C3F34_09550 ENOG4105C4X radical SAM domain protein C3F34_09555 ENOG4105ENH Sulfatase C3F34_09575 ENOG4108Z4X TRANSCRIPTIONal C3F34_09580 ENOG4106UX7 integral membrane protein C3F34_09590 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) C3F34_09595 ENOG4105W8H transhydrogenase (subunit alpha C3F34_09600 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) C3F34_09610 ENOG4105E0K tonB-dependent siderophore receptor C3F34_09635 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) C3F34_09640 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase C3F34_09645 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase C3F34_09650 ENOG4105BZU Histidine kinase C3F34_09655 ENOG4105C6T cysteine synthase C3F34_09670 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) C3F34_09675 ENOG4105DXN mazG family C3F34_09680 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein C3F34_09685 ENOG4105DJ0 Poly(A) Polymerase C3F34_09690 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase C3F34_09705 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) C3F34_09715 ENOG4105N42 UPF0307 protein C3F34_09720 ENOG4105CEY Amp-dependent synthetase and ligase C3F34_09735 ENOG4105CYM Glutathione S-transferase C3F34_09755 ENOG4105W39 Membrane C3F34_09775 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) C3F34_09790 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) C3F34_09795 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) C3F34_09810 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) C3F34_09820 ENOG4105C9X ppx gppa phosphatase C3F34_09830 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) C3F34_09835 ENOG4105II7 pyrroline-5-carboxylate reductase C3F34_09840 ENOG4108VIA integral membrane protein C3F34_09845 ENOG4105C2M dna polymerase I C3F34_09865 ENOG4107QHF type ii secretion system protein e C3F34_09875 ENOG4108ZHJ Organic hydroperoxide resistance protein C3F34_09945 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) C3F34_09955 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) C3F34_10020 ENOG4108Z0R Transferase C3F34_10025 ENOG41072GX Peptidase M22 Glycoprotease C3F34_10030 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) C3F34_10045 ENOG4105C4W S-formylglutathione hydrolase C3F34_10055 ENOG4105DJV ribulose-phosphate 3-epimerase C3F34_10065 ENOG4105E3B Multicopper oxidase C3F34_10085 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) C3F34_10095 ENOG4105DWF phosphomethylpyrimidine kinase C3F34_10100 ENOG4107XGZ Hydrolase C3F34_10110 ENOG4105EW9 transcriptional regulator AsnC family C3F34_10125 ENOG4105M4H endoribonuclease L-psp C3F34_10130 ENOG4105C85 amino acid C3F34_10135 ENOG4105EXC Acyl-transferase C3F34_10140 ENOG4108YXA Membrane C3F34_10155 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) C3F34_10165 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) C3F34_10170 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) C3F34_10180 ENOG4105KEG ribosomal-protein-alanine acetyltransferase C3F34_10190 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) C3F34_10195 ENOG4105C3M thioredoxin reductase C3F34_10200 ENOG4105CNU cell division protein FtsK C3F34_10205 ENOG4105DUM transcriptional regulator, lysR family C3F34_10225 ENOG4107QMS site-determining protein C3F34_10230 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) C3F34_10240 ENOG4106HNH Acyl-transferase C3F34_10245 ENOG4108ZG0 Ompa motb domain protein C3F34_10250 ENOG4105C4R Atp-dependent dna helicase C3F34_10255 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) C3F34_10260 ENOG4107QKV phosphomannomutase C3F34_10265 ENOG4105CAS nag kinase C3F34_10275 ENOG4105E7A Glutamine amidotransferase C3F34_10290 ENOG4105VDB UPF0125 protein C3F34_10300 ENOG41090R7 Ferric uptake C3F34_10305 ENOG4105EYH Exonuclease C3F34_10310 ENOG4107RH8 nuclease SbcCD subunit D C3F34_10325 ENOG4105ECP epimerase C3F34_10330 ENOG4105MWK D-amino acid dehydrogenase, small subunit C3F34_10335 ENOG4105D52 delta-aminolevulinic acid dehydratase C3F34_10340 ENOG4108VUY thioesterase Superfamily protein C3F34_10345 ENOG4105CW7 secretion protein, HlyD family C3F34_10350 ENOG4105C0R drug resistance transporter emrb qaca subfamily C3F34_10355 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) C3F34_10365 ENOG4105DFP Integrase C3F34_10375 ENOG4108UUM single-stranded DNA-binding protein C3F34_10590 ENOG4105ED4 portal protein C3F34_10595 ENOG4105DFP Integrase C3F34_10645 ENOG4105ETT transcriptional Regulator, LysR family C3F34_10660 ENOG4105C26 Dehydrogenase C3F34_10665 ENOG4107QZF nitrite reductase NADPH large subunit C3F34_10715 ENOG4107R3N Filamentation induced by cAMP protein fic C3F34_10760 ENOG4105UYK outer membrane protein a C3F34_10780 ENOG4105DFG type I secretion outer membrane protein C3F34_10790 ENOG4105C42 Type I secretion membrane fusion protein (HlyD C3F34_10820 ENOG4105C0R drug resistance transporter emrb qaca subfamily C3F34_10825 ENOG4105DUU IucA IucC family protein C3F34_10830 ENOG4105DJU Siderophore biosynthesis protein C3F34_10890 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase C3F34_10900 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase C3F34_10905 ENOG4105DHQ Histidine kinase C3F34_10910 ENOG4105CK6 Two component transcriptional regulator (Winged helix family C3F34_10935 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein C3F34_10940 ENOG4105BZC d-serine deaminase C3F34_10945 ENOG4105W8I Transcriptional regulator C3F34_10960 ENOG4107HP6 Transcriptional regulator C3F34_10965 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase C3F34_10970 ENOG4108Z7F N-acetyltransferase C3F34_10985 ENOG4105DNH Major Facilitator C3F34_10990 ENOG4105DXM phenylacetic acid degradation protein C3F34_10995 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit C3F34_11000 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit C3F34_11005 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit C3F34_11010 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit C3F34_11015 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) C3F34_11020 ENOG4105E39 Enoyl-CoA hydratase C3F34_11025 ENOG4108UKI Enoyl-CoA hydratase C3F34_11030 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase C3F34_11035 ENOG4105CHU acetyl-coa acetyltransferase C3F34_11040 ENOG4105DZS Phenylacetate-CoA ligase C3F34_11045 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein C3F34_11050 ENOG4108Z0R Transferase C3F34_11065 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) C3F34_11075 ENOG4105D1F ATP-binding protein C3F34_11115 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) C3F34_11125 ENOG4105D0S secretion protein (HlyD C3F34_11135 ENOG4108UNF response regulator C3F34_11140 ENOG4105M3Z response regulator C3F34_11145 ENOG4108ZGA chew protein C3F34_11150 ENOG4105C8Q Methyl-accepting chemotaxis C3F34_11155 ENOG4105CBS Chea signal transduction histidine kinase C3F34_11165 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) C3F34_11180 ENOG4105WD1 Membrane C3F34_11185 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein C3F34_11240 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) C3F34_11250 ENOG4105EM2 membrane C3F34_11255 ENOG4105C2C drug resistance transporter, Bcr CflA C3F34_11265 ENOG4105EEQ Na H antiporter C3F34_11280 ENOG4105EQK -acetyltransferase C3F34_11285 ENOG4105JQZ Methyltransferase C3F34_11295 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain C3F34_11300 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain C3F34_11315 ENOG4105HBR Rna-binding protein C3F34_11325 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) C3F34_11330 ENOG4105EEI dihydropteroate synthase C3F34_11370 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) C3F34_11385 ENOG4105CSH Transporter C3F34_11400 ENOG4105C0M Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity) C3F34_11405 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) C3F34_11410 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) C3F34_11425 ENOG41080IJ Diacylglycerol kinase C3F34_11430 ENOG4105BZS acriflavin resistance protein C3F34_11445 ENOG4105E4C Lytic transglycosylase catalytic C3F34_11450 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) C3F34_11460 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) C3F34_11465 ENOG4108RRZ Transcription elongation factor GreB C3F34_11605 ENOG4105D5K Hemolysin activator protein C3F34_11610 ENOG4105CKT filamentous hemagglutinin C3F34_11645 ENOG4105C26 Dehydrogenase C3F34_11675 ENOG4107RAQ aminopeptidase C3F34_11680 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) C3F34_11685 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) C3F34_11715 ENOG4105D0A hydroxylase C3F34_11720 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family C3F34_11730 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) C3F34_11740 ENOG4105W4M Transport-associated protein C3F34_11745 ENOG4105EBR Carboxylesterase C3F34_11750 ENOG4105E09 nadh pyrophosphatase C3F34_11760 ENOG4107RZZ dna polymerase iii epsilon subunit C3F34_11765 ENOG4105E9H Lytic Murein transglycosylase C3F34_11775 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component C3F34_11780 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component C3F34_11785 ENOG4108JQ5 ABC transporter C3F34_11815 ENOG4108IQI permease C3F34_11830 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) C3F34_11835 ENOG4105EKE dihydroorotase C3F34_11845 ENOG4105DAA L-lactate C3F34_11850 ENOG41073TP transcriptional regulator C3F34_11860 ENOG4105CXG d-lactate dehydrogenase C3F34_11865 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase C3F34_11900 ENOG4107EFR Flavocytochrome c C3F34_11905 ENOG4106P55 Transcriptional regulator C3F34_11925 ENOG4106P55 Transcriptional regulator C3F34_11935 ENOG41090B9 response to stress C3F34_11940 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) C3F34_11950 ENOG4105EU0 Major facilitator Superfamily C3F34_11970 ENOG4105WDY DNA (cytosine-5-)-methyltransferase C3F34_11980 ENOG4105C3R Methionine synthase C3F34_11985 ENOG4105CJ3 phosphate transporter C3F34_11995 ENOG4105CND Glycosyl transferase, family 2 C3F34_12000 ENOG4107BJW polysaccharide deacetylase C3F34_12010 ENOG4105C5Q Transcriptional regulator C3F34_12020 ENOG4107QZF nitrite reductase NADPH large subunit C3F34_12025 ENOG4105VCQ rubredoxin C3F34_12030 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) C3F34_12050 ENOG4108MRJ C3F34_12055 ENOG4105C2I pirin domain protein C3F34_12065 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) C3F34_12070 ENOG4105NX3 Membrane C3F34_12085 ENOG4105K89 arsenate reductase C3F34_12090 ENOG41082YX Transcriptional regulator, arsr family C3F34_12095 ENOG4105D6J arsenicaL-resistance protein C3F34_12100 ENOG4105CAU Arsenical resistance protein, ArsH C3F34_12105 ENOG4105EUJ GTP cyclohydrolase i C3F34_12125 ENOG4107QYG anthranilate phosphoribosyltransferase C3F34_12130 ENOG4105DDQ anthranilate synthase C3F34_12145 ENOG4105NF4 modulator of drug activity C3F34_12175 ENOG4105CKI cobalamin synthesis protein C3F34_12180 ENOG4108VWS Yaeq family C3F34_12200 ENOG4105BZU Histidine kinase C3F34_12215 ENOG4107XDY Nicotinamide Mononucleotide Transporter C3F34_12245 ENOG4107RNH Outer membrane receptor FepA C3F34_12265 ENOG4108UJV acyl-CoA thioesterase i C3F34_12270 ENOG4108I0Y (ABC) transporter C3F34_12275 ENOG4105CV6 ABC transporter, permease C3F34_12280 ENOG4107ZXI Rhomboid family C3F34_12285 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase C3F34_12325 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) C3F34_12330 ENOG4107QNR UPF0135 protein C3F34_12335 ENOG4105C0H protease C3F34_12350 ENOG4105C37 (CBS) domain C3F34_12360 ENOG4107RET Isocitrate lyase C3F34_12385 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) C3F34_12395 ENOG4105C6K Malic enzyme C3F34_12400 ENOG4105BZU Histidine kinase C3F34_12405 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) C3F34_12410 ENOG4105SYT Methylenetetrahydrofolate reductase C3F34_12415 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) C3F34_12455 ENOG4105EGD dinuclear metal center protein, YbgI family C3F34_12465 ENOG4108IPT Naphthoate synthase C3F34_12475 ENOG4108YYC ycei family C3F34_12485 ENOG4108ZUB Lysine exporter protein (Lyse ygga) C3F34_12490 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen C3F34_12505 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) C3F34_12510 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) C3F34_12530 ENOG4107R11 Transcriptional regulator C3F34_12535 ENOG4108IJ6 ABC transporter C3F34_12545 ENOG4108I5D sulfate abc transporter C3F34_12555 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein C3F34_12560 ENOG4105YAZ 4-amino-4-deoxychorismate lyase C3F34_12565 ENOG4105HHA aminodeoxychorismate lyase C3F34_12580 ENOG4108IYU L-aspartate oxidase C3F34_12585 ENOG4105C0H protease C3F34_12595 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) C3F34_12600 ENOG4105C3F Signal peptidase i C3F34_12610 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) C3F34_12615 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) C3F34_12625 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) C3F34_12630 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) C3F34_12635 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase C3F34_12680 ENOG4108KHP Diguanylate cyclase C3F34_12695 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) C3F34_12725 ENOG4105KVH Transcriptional regulator C3F34_12740 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase C3F34_12745 ENOG4105GAV receptor C3F34_12755 ENOG4108JPW Aminotransferase C3F34_12760 ENOG4105DY8 decarboxylase C3F34_12765 ENOG4105F7P transcriptional regulator AsnC family C3F34_12770 ENOG4107RA9 decarboxylase C3F34_12775 ENOG4105C85 amino acid C3F34_12780 ENOG4105CVA phosphate C3F34_12785 ENOG4105C8U phosphate abc transporter C3F34_12795 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) C3F34_12800 ENOG4105ERU peptidase C3F34_12810 ENOG4107QTF adenylosuccinate lyase C3F34_12835 ENOG4108Z0R Transferase C3F34_12840 ENOG4105DZ1 carboxypeptidase C3F34_12855 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) C3F34_12860 ENOG4108K5P (LipO)protein C3F34_12865 ENOG4105EJC lysr family transcriptional regulator C3F34_12870 ENOG4105C8Y Acetylornithine aminotransferase C3F34_12875 ENOG4105M2J Glutaredoxin C3F34_12885 ENOG4107QS8 (LipO)protein C3F34_12930 ENOG4105C84 Histidine ammonia-lyase C3F34_12950 ENOG4107T3I fad-binding protein C3F34_12960 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) C3F34_12970 ENOG4105C2D reductase C3F34_12975 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) C3F34_12990 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) C3F34_12995 ENOG4105EA8 2-Nitropropane dioxygenase C3F34_13030 ENOG4105DAN ATP-dependent protease C3F34_13045 ENOG4105DHU Bile acid C3F34_13065 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein C3F34_13070 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) C3F34_13075 ENOG4105D22 carbon starvation protein C3F34_13080 ENOG4105VCD cytoplasmic protein C3F34_13085 ENOG4105C7R Atpase associated with various cellular activities aaa_3 C3F34_13095 ENOG4105F8C transglutaminase domain-containing protein C3F34_13140 ENOG4108NF7 phage-type endonuclease C3F34_13210 ENOG4106CVF DNA replication protein C3F34_13370 ENOG41080ET plasmid maintenance system killer protein C3F34_13375 ENOG41082AG Plasmid maintenance system antidote protein C3F34_13445 ENOG4108P8R C3F34_13460 ENOG4105CVR type I restriction-modification system C3F34_13485 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 C3F34_13500 ENOG4105C7N Xanthine uracil vitamin C permease C3F34_13505 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) C3F34_13510 ENOG4105DS1 cytochrome b561 C3F34_13525 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) C3F34_13535 ENOG4105CFH Aspartokinase C3F34_13545 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase C3F34_13565 ENOG4108UMN azlc family C3F34_13570 ENOG4108XM1 transcriptional regulator AsnC family C3F34_13580 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis C3F34_13595 ENOG4105CPC Aldo Keto reductase C3F34_13600 ENOG4107RYR Transcriptional regulator, Crp Fnr family C3F34_13605 ENOG4108UKZ OsmC family C3F34_13610 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit C3F34_13635 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) C3F34_13650 ENOG4105CXT aspartate transcarbamylase C3F34_13655 ENOG4105CD3 dihydroorotase C3F34_13680 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) C3F34_13685 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) C3F34_13690 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 C3F34_13710 ENOG4105CCF Lysine exporter protein (Lyse ygga) C3F34_13725 ENOG4105N0V mono-oxygenase ydhR C3F34_13730 ENOG41062JF Transcriptional regulator C3F34_13740 ENOG4105E0K tonB-dependent siderophore receptor C3F34_13745 ENOG4105CZE histidine utilization repressor C3F34_13760 ENOG4105C85 amino acid C3F34_13770 ENOG41088SP formiminoglutamate hydrolase C3F34_13775 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 C3F34_13785 ENOG4105CFQ glutamine synthetase C3F34_13805 ENOG4105DDY UPF0142 protein ycaO C3F34_13810 ENOG4105CEP NADH dehydrogenase C3F34_13815 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein C3F34_13820 ENOG4105E2B Taurine dioxygenase C3F34_13825 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme C3F34_13845 ENOG4105HMI Membrane C3F34_13870 ENOG4105W1Y Transcriptional regulator C3F34_14235 ENOG4105C2X Arabinose 5-phosphate isomerase C3F34_14240 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase C3F34_14250 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA C3F34_14255 ENOG4108IUZ ABC transporter C3F34_14285 ENOG4108Z4U Ferredoxin C3F34_14315 ENOG4105HEI LysR family (Transcriptional regulator C3F34_14320 ENOG4105C57 major facilitator superfamily C3F34_14335 ENOG4107U2T alpha beta C3F34_14360 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family C3F34_14370 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii C3F34_14375 ENOG4105C4M (Ubiquinol oxidase) subunit I C3F34_14385 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) C3F34_14390 ENOG4105VAW lrga family C3F34_14395 ENOG41067MG lrgb family C3F34_14405 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family C3F34_14435 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) C3F34_14440 ENOG4105FB2 class II Aldolase C3F34_14445 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family C3F34_14455 ENOG4105DKK Benzoate C3F34_14480 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family C3F34_14485 ENOG4105CF7 AraC family transcriptional regulator C3F34_14490 ENOG4105D2S major facilitator superfamily C3F34_14500 ENOG41061TZ Short-chain dehydrogenase reductase Sdr C3F34_14525 ENOG4105F2Z 3-oxoadipate enol-lactonase C3F34_14530 ENOG4105CHU acetyl-coa acetyltransferase C3F34_14535 ENOG4107QNJ CoA-transferase subunit B C3F34_14540 ENOG4107QP7 CoA-transferase subunit A C3F34_14550 ENOG4105NN7 muconolactone delta-isomerase C3F34_14555 ENOG4105DTQ mandelate racemase muconate lactonizing C3F34_14560 ENOG4108KB2 LysR family Transcriptional regulator C3F34_14580 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) C3F34_14600 ENOG4105FUY alpha subunit C3F34_14610 ENOG4105CHR reductase C3F34_14625 ENOG4105F57 Anthranilate dioxygenase reductase C3F34_14630 ENOG4108YS2 small subunit C3F34_14635 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit C3F34_14650 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family C3F34_14660 ENOG4107S76 domain protein C3F34_14675 ENOG4107RGH Aldehyde dehydrogenase C3F34_14690 ENOG4105ZIA Phage protein gp16 C3F34_14710 ENOG4105K70 DNA-binding protein C3F34_14790 ENOG4105CF2 Mu-like prophage FluMu protein GP28 C3F34_14815 ENOG4105QIB mu-like prophage Flumu protein gp29 C3F34_14840 ENOG4105EFV Major head subunit C3F34_14910 ENOG4108T86 baseplate J family protein C3F34_14950 ENOG4105DRR Transcriptional regulator, GntR family C3F34_15035 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) C3F34_15040 ENOG4105CDU Replicative dna helicase C3F34_15060 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) C3F34_15065 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) C3F34_15070 ENOG4105CCU oxidase (Subunit III) C3F34_15075 ENOG4105BZ9 Cytochrome C oxidase, subunit I C3F34_15080 ENOG4105E2S oxidase) subunit II C3F34_15105 ENOG4105DEN Luciferase family C3F34_15120 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) C3F34_15125 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) C3F34_15130 ENOG4105FFC UPF0187 protein C3F34_15150 ENOG4105C1G acyl-Coa dehydrogenase C3F34_15185 ENOG4105D06 uba thif-type nad fad binding protein C3F34_15195 ENOG4105KRF dihydroneopterin aldolase C3F34_15215 ENOG4107S74 Lysophospholipid transporter LplT C3F34_15220 ENOG4105CFU surface antigen C3F34_15225 ENOG4105MA0 exported protein C3F34_15250 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase C3F34_15285 ENOG4107QIJ Aconitate hydratase 2 C3F34_15300 ENOG4107QPK )-transporter C3F34_15310 ENOG4105EW9 transcriptional regulator AsnC family C3F34_15340 ENOG4105CD8 aminopeptidase N C3F34_15355 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH C3F34_15390 ENOG4105DKK Benzoate C3F34_15395 ENOG4108NIW Leucine export protein LeuE C3F34_15400 ENOG4107QV2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) C3F34_15405 ENOG4105HEI LysR family (Transcriptional regulator C3F34_15415 ENOG4108KF1 Membrane C3F34_15425 ENOG4105CHR reductase C3F34_15440 ENOG4107QMP dna polymerase iii subunits gamma and tau C3F34_15450 ENOG4105C0A alcohol dehydrogenase C3F34_15475 ENOG4105CBC glutamate synthase C3F34_15480 ENOG4105WH1 Two component transcriptional regulator luxr family C3F34_15485 ENOG4105BZU Histidine kinase C3F34_15490 ENOG4105EZE Cupin 4 family protein C3F34_15495 ENOG4108UHJ MAF-like protein C3F34_15515 ENOG4105D2N Aldolase C3F34_15520 ENOG4108TZV Membrane C3F34_15525 ENOG4108RCM Nitroreductase C3F34_15535 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) C3F34_15545 ENOG4105CX6 glutaminyL-tRNA synthetase C3F34_15555 ENOG4108T58 Mg2 transport protein CorA C3F34_15575 ENOG4105EW9 transcriptional regulator AsnC family C3F34_15580 ENOG4105CK7 Sodium proline symporter C3F34_15590 ENOG4108JA2 transcriptioN-repair coupling factor C3F34_15600 ENOG4105F8J Adenylate Guanylate cyclase C3F34_15605 ENOG4108ZIT Ferredoxin, 2FE-2S C3F34_15620 ENOG4108Z4V iron-sulfur cluster assembly C3F34_15625 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins C3F34_15635 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family C3F34_15650 ENOG4105K70 DNA-binding protein C3F34_15655 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) C3F34_15680 ENOG4105K59 histidine triad (HIT) protein C3F34_15705 ENOG4105C28 cystathionine C3F34_15715 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) C3F34_15745 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) C3F34_15750 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) C3F34_15780 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) C3F34_15835 ENOG4105D8G Major Facilitator superfamily C3F34_15845 ENOG4105BZU Histidine kinase C3F34_15855 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase C3F34_15860 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein C3F34_15910 ENOG4105CMR udp-glucose 4-epimerase C3F34_15930 ENOG41064T2 transcriptional regulator, lysR family C3F34_15935 ENOG4105C1G acyl-Coa dehydrogenase C3F34_15955 ENOG4107QJZ Glycosyl transferase, family 2 C3F34_15990 ENOG4105T38 integral membrane protein C3F34_15995 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family C3F34_16000 ENOG4107RZC phospholipase d C3F34_16020 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) C3F34_16025 ENOG4105CZM Major Facilitator C3F34_16030 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) C3F34_16035 ENOG4108ZX5 transcriptional regulator C3F34_16045 ENOG4105BZ1 (ABC) transporter C3F34_16060 ENOG4105N14 lysine exporter protein LysE YggA C3F34_16070 ENOG4105CUY Mechanosensitive ion channel C3F34_16075 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme C3F34_16095 ENOG41080HT Transcriptional regulator, arsr family C3F34_16100 ENOG4105E55 glycerol-3-phosphate acyltransferase C3F34_16105 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) C3F34_16110 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) C3F34_16115 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) C3F34_16120 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) C3F34_16125 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) C3F34_16130 ENOG4105C2W permease C3F34_16135 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase C3F34_16140 ENOG4105C6T cysteine synthase C3F34_16145 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase C3F34_16155 ENOG4105E39 Enoyl-CoA hydratase C3F34_16160 ENOG4107QX3 carboxylase C3F34_16165 ENOG4105C1G acyl-Coa dehydrogenase C3F34_16170 ENOG4108SGK Tetr family transcriptional regulator C3F34_16175 ENOG4105CEY Amp-dependent synthetase and ligase C3F34_16185 ENOG4105DVA methyltransferase C3F34_16205 ENOG4107RNU major facilitator superfamily MFS_1 C3F34_16210 ENOG4107QZF nitrite reductase NADPH large subunit C3F34_16215 ENOG4108IFG nitrite reductase, (NAD(P)H) C3F34_16230 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) C3F34_16245 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) C3F34_16250 ENOG4105CVM Molybdenum cofactor synthesis domain protein C3F34_16255 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein C3F34_16260 ENOG4105E0C molybdate abc transporter C3F34_16265 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) C3F34_16275 ENOG4105CKD glutathione-regulated potassium-efflux system protein C3F34_16295 ENOG4105CJ1 ABC, transporter C3F34_16300 ENOG4107QWP ABC-2 type transporter C3F34_16305 ENOG4107QWP ABC-2 type transporter C3F34_16310 ENOG4108IJ0 Aspartate ammonia-lyase C3F34_16315 ENOG4107YNJ LysR family Transcriptional regulator C3F34_16320 ENOG4105EXG Transcriptional regulator C3F34_16345 ENOG4105NI3 Protein of unknown function (DUF3237) C3F34_16350 ENOG4105J5J Outer membrane porin C3F34_16355 ENOG4105C1G acyl-Coa dehydrogenase C3F34_16360 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase C3F34_16370 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase C3F34_16375 ENOG4108SC4 )-transporter C3F34_16390 ENOG4105E3J oxidoreductase C3F34_16405 ENOG4105E6M Sulphatase-modifying factor protein C3F34_16410 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) C3F34_16415 ENOG4105D2S major facilitator superfamily C3F34_16420 ENOG4105EPF Outer membrane porin C3F34_16435 ENOG4105EW9 transcriptional regulator AsnC family C3F34_16440 ENOG4105C8Y Acetylornithine aminotransferase C3F34_16460 ENOG4105C85 amino acid C3F34_16480 ENOG4105CK2 sodium dicarboxylate symporter C3F34_16500 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family C3F34_16520 ENOG4105CEY Amp-dependent synthetase and ligase C3F34_16530 ENOG4105DJV ribulose-phosphate 3-epimerase C3F34_16535 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) C3F34_16545 ENOG41082F9 transcriptional regulator C3F34_16565 ENOG4105CC0 LysR family Transcriptional regulator C3F34_16570 ENOG4105ENJ RND efflux system, outer membrane lipoprotein C3F34_16585 ENOG4105CBN LysR family transcriptional regulator C3F34_16595 ENOG4105EEF Alkane 1-monooxygenase C3F34_16600 ENOG4105VCQ rubredoxin C3F34_16620 ENOG4105SG9 biopolymer transport protein, ExbD C3F34_16630 ENOG4105WQ5 TonB family C3F34_16635 ENOG4108TGY Glutathione S-transferase C3F34_16640 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) C3F34_16645 ENOG4105DEN Luciferase family C3F34_16650 ENOG4105CH2 amidohydrolase C3F34_16660 ENOG4105EAB amino acid AbC transporter C3F34_16665 ENOG4105F87 Dehydratase C3F34_16675 ENOG4105E5Q amino acid AbC transporter C3F34_16680 ENOG4105CDA abc transporter atp-binding protein C3F34_16695 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) C3F34_16700 ENOG4107R0V Pyruvate dehydrogenase C3F34_16705 ENOG4105CPP Dehydrogenase, E1 component C3F34_16720 ENOG4105CHR reductase C3F34_16750 ENOG4105VYA Uncharacterized conserved protein (DUF2132) C3F34_16755 ENOG4108WUH Transcriptional regulator, TetR family C3F34_16760 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family C3F34_16840 ENOG4105EV9 Alpha Beta Hydrolase C3F34_16860 ENOG4105CMU LysR family (Transcriptional regulator C3F34_16865 ENOG4105VAW lrga family C3F34_16870 ENOG41067MG lrgb family C3F34_16885 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) C3F34_16890 ENOG4108YZT Adenosylcobinamide kinase C3F34_16900 ENOG4107VXZ Hydrolase C3F34_16915 ENOG4105VEQ Cold shock protein C3F34_16930 ENOG4108Z66 YbaK ebsC protein C3F34_16935 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase C3F34_16940 ENOG4105E8V Alpha Beta Hydrolase Fold protein C3F34_16945 ENOG41077RS Phosphatase C3F34_16960 ENOG4108HPI phosphatidate Cytidylyltransferase C3F34_17005 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit C3F34_17010 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) C3F34_17025 ENOG4105BZU Histidine kinase C3F34_17035 ENOG4105E66 phosphoriboisomerase A C3F34_17040 ENOG4105C7B Threonine dehydratase C3F34_17055 ENOG4105CZN Potassium uptake protein C3F34_17060 ENOG4105HDD phospholipase C3F34_17085 ENOG4105PV3 Inner membrane protein yqiJ C3F34_17100 ENOG4105C4M (Ubiquinol oxidase) subunit I C3F34_17105 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii C3F34_17130 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) C3F34_17145 ENOG4105C1G acyl-Coa dehydrogenase C3F34_17150 ENOG4105C1G acyl-Coa dehydrogenase C3F34_17155 ENOG4108MJ3 acetyltransferase C3F34_17160 ENOG4105EEF Alkane 1-monooxygenase C3F34_17165 ENOG4105E7U AraC family transcriptional regulator C3F34_17170 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) C3F34_17175 ENOG4105CNM Receptor C3F34_17195 ENOG4107TSN permease C3F34_17200 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) C3F34_17225 ENOG4105CNI cell division protein FtsW C3F34_17235 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) C3F34_17240 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) C3F34_17275 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase C3F34_17290 ENOG4108KB2 LysR family Transcriptional regulator C3F34_17295 ENOG4105DTQ mandelate racemase muconate lactonizing C3F34_17300 ENOG4105NN7 muconolactone delta-isomerase C3F34_17310 ENOG4105FUY alpha subunit C3F34_17315 ENOG4108UKV benzoate 1,2-dioxygenase C3F34_17320 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein C3F34_17325 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase C3F34_17330 ENOG4105DKK Benzoate C3F34_17335 ENOG4107QP7 CoA-transferase subunit A C3F34_17340 ENOG4107QNJ CoA-transferase subunit B C3F34_17345 ENOG4105CHU acetyl-coa acetyltransferase C3F34_17350 ENOG4105F2Z 3-oxoadipate enol-lactonase C3F34_17360 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F C3F34_17365 ENOG4105C1G acyl-Coa dehydrogenase C3F34_17370 ENOG4105ETT transcriptional Regulator, LysR family C3F34_17375 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) C3F34_17400 ENOG4105K4T epimerase C3F34_17420 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase C3F34_17425 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 C3F34_17430 ENOG4105VEJ Heat shock protein C3F34_17440 ENOG4105Y3E Modulates RecA activity (By similarity) C3F34_17455 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) C3F34_17475 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane C3F34_17480 ENOG4105DZP Membrane-associated zinc metalloprotease C3F34_17490 ENOG4105KNE Phosphatidate cytidylyltransferase C3F34_17495 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) C3F34_17515 ENOG4105CUX Signal transduction histidine kinase C3F34_17520 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family C3F34_17530 ENOG4105CC0 LysR family Transcriptional regulator C3F34_17535 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) C3F34_17545 ENOG4105CWM branched-chain amino acid transport system II carrier protein C3F34_17565 ENOG4105EE5 Membrane protein terC C3F34_17585 ENOG4107QP3 malate synthase g C3F34_17590 ENOG4105D6Z AFG1 family ATPase C3F34_17600 ENOG4105DWU Membrane C3F34_17620 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) C3F34_17625 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) C3F34_17640 ENOG4108Z6B deaminase C3F34_17680 ENOG4105R8C Transcriptional regulator C3F34_17685 ENOG4105F8V Hydrolase, tatD family C3F34_17695 ENOG4107QRG dna polymerase iii C3F34_17705 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) C3F34_17710 ENOG4105BZ1 (ABC) transporter C3F34_17725 ENOG4105FA0 parb-like partition protein C3F34_17730 ENOG4107QJE Chromosome Partitioning Protein C3F34_17735 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) C3F34_17740 ENOG4108S0S Nucleotidyl transferase C3F34_17745 ENOG4105EHM Aminoglycoside phosphotransferase C3F34_17750 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) C3F34_17760 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) C3F34_17765 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) C3F34_17775 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) C3F34_17780 ENOG4105K8N protein family UPF0079, ATPase C3F34_17800 ENOG4105I08 Pseudouridine synthase C3F34_17805 ENOG4108VMM UPF0756 membrane protein C3F34_17810 ENOG4105DZ2 Transcriptional regulator C3F34_17815 ENOG4105F27 Major Facilitator C3F34_17820 ENOG4105EYW Ion transport protein C3F34_17825 ENOG4107QUV Domain protein C3F34_17835 ENOG4105C0A alcohol dehydrogenase C3F34_17845 ENOG4107RR1 TRANSCRIPTIONal C3F34_17855 ENOG4107Y9U Membrane C3F34_17880 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) C3F34_17890 ENOG4105CV1 Transketolase (EC 2.2.1.1) C3F34_17925 ENOG4105D9P serine threonine protein kinase C3F34_17945 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) C3F34_17950 ENOG4105VCC 30S ribosomal protein S21 C3F34_17955 ENOG4105KTH gatB Yqey C3F34_17970 ENOG4105ERG peptidase m48, ste24p C3F34_17990 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase C3F34_18025 ENOG41069NU Nitroreductase C3F34_18035 ENOG4105C1J atp-dependent rna helicase C3F34_18040 ENOG4105VEQ Cold shock protein C3F34_18050 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) C3F34_18055 ENOG4105M08 Membrane C3F34_18075 ENOG4108K3A Glutathione S-transferase C3F34_18085 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) C3F34_18105 ENOG4105CHB tonB-dependent Receptor C3F34_18110 ENOG4105DZG Dehydrogenase C3F34_18115 ENOG4105TW1 Carbohydrate-selective porin OprB C3F34_18120 ENOG4106JPM 3-dehydroshikimate dehydratase C3F34_18125 ENOG4105FF2 Type I DHQase C3F34_18130 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha C3F34_18135 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta C3F34_18140 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase C3F34_18145 ENOG4105D2S major facilitator superfamily C3F34_18150 ENOG4105F2Z 3-oxoadipate enol-lactonase C3F34_18155 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase C3F34_18160 ENOG4105CHU acetyl-coa acetyltransferase C3F34_18165 ENOG4107QNJ CoA-transferase subunit B C3F34_18170 ENOG4107QP7 CoA-transferase subunit A C3F34_18185 ENOG410814C multidrug resistance protein C3F34_18205 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH C3F34_18305 ENOG4105QHH Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that counteracts the effect of the YafQ toxin. YafQ and DinJ together bind their own promoter, and by analogy to other TA modules probably repress its expression C3F34_18465 ENOG4105MZU cell filamentation protein C3F34_18485 ENOG4105G6Z alkaline phosphatase C3F34_18490 ENOG4105G6Z alkaline phosphatase C3F34_18540 ENOG4105CPW cytochrome b561 C3F34_18555 ENOG410841Q phosphoesterase PA-phosphatase related protein C3F34_18600 ENOG4105DHQ Histidine kinase C3F34_18620 ENOG4105XUP Phage derived protein Gp49-like (DUF891) C3F34_18715 ENOG4105E4P ATPase (AAA C3F34_18740 ENOG4105PGM cation diffusion facilitator family transporter C3F34_18765 ENOG41081QV Universal stress protein C3F34_18770 ENOG4105KBH arsR family transcriptional regulator C3F34_18780 ENOG4105D6J arsenicaL-resistance protein C3F34_18785 ENOG4105CAU Arsenical resistance protein, ArsH C3F34_18790 ENOG4105C3M thioredoxin reductase C3F34_18795 ENOG4105H3G oxidoreductase C3F34_18805 ENOG4105CHH sulfate transporter C3F34_18815 ENOG4108YXA Membrane C3F34_18835 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) C3F34_18860 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii C3F34_18865 ENOG4105C4M (Ubiquinol oxidase) subunit I C3F34_18950 ENOG41080HT Transcriptional regulator, arsr family C3F34_19045 ENOG4105C94 Transporter C3F34_19050 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) C3F34_19055 ENOG4105C26 Dehydrogenase C3F34_19090 ENOG4105FA0 parb-like partition protein C3F34_19095 ENOG4107QJE Chromosome Partitioning Protein C3F34_19170 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) C3F34_19195 ENOG4108C66 Inherit from COG: DNA primase C3F34_19225 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) C3F34_19240 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) C3F34_19245 ENOG4108YZ9 Urea amidohydrolase subunit gamma C3F34_19260 ENOG4105CQM Urea amidohydrolase subunit alpha C3F34_19275 ENOG4105VT2 5-hydroxyisourate hydrolase C3F34_19280 ENOG4105C2W permease C3F34_19295 ENOG4105DHG Allantoate amidinohydrolase C3F34_19300 ENOG41061H0 Monooxygenase C3F34_19305 ENOG4105SKE transcriptional Regulator LysR family C3F34_19320 ENOG4105C2W permease C3F34_19325 ENOG4105DRB nucleoside-specific channel-forming protein C3F34_19340 ENOG4105EMY transcriptional regulator C3F34_19390 ENOG4105C4W S-formylglutathione hydrolase C3F34_19405 ENOG4108I6A alcohol dehydrogenase C3F34_19415 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase C3F34_19425 ENOG4108WUH Transcriptional regulator, TetR family C3F34_19430 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein C3F34_19465 ENOG4105E4P ATPase (AAA C3F34_19505 ENOG4107QPK )-transporter C3F34_19545 ENOG4105C59 p-type ATPase C3F34_19550 ENOG4107PU6 Membrane C3F34_19555 ENOG4105GR3 Histidine kinase C3F34_19570 ENOG4105E3B Multicopper oxidase C3F34_19600 ENOG4105H3G oxidoreductase C3F34_19605 ENOG4105CE1 Ferrous iron transport protein b C3F34_19650 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) C3F34_19710 ENOG4105W1Y Transcriptional regulator C3F34_19720 ENOG4105CHH sulfate transporter C3F34_19740 ENOG4105VUH addiction module killer protein C3F34_19745 ENOG4105YES addiction module antidote protein C3F34_19885 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) C3F34_20010 ENOG4108NF7 phage-type endonuclease C3F34_20080 ENOG4106CVF DNA replication protein