locus-tag	class	description
BE1S18E01_00020	COG0592	DNA-directed DNA polymerase activity
BE1S18E01_00040	COG0187	DNA topoisomerase II activity
BE1S18E01_00070	COG0488	(ABC) transporter
BE1S18E01_00120	COG0596	Alpha beta hydrolase
BE1S18E01_00130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BE1S18E01_00140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BE1S18E01_00150	COG0625	glutathione transferase activity
BE1S18E01_00170	COG0733	neurotransmitter:sodium symporter activity
BE1S18E01_00250	COG2233	PERMEase
BE1S18E01_00280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_00350	COG2814	Major facilitator Superfamily
BE1S18E01_00360	COG0656	L-ascorbic acid biosynthetic process
BE1S18E01_00370	COG0583	DNA-binding transcription factor activity
BE1S18E01_00390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_00400	COG1064	alcohol dehydrogenase
BE1S18E01_00410	COG2818	Glycosylase
BE1S18E01_00440	COG1194	a g-specific adenine glycosylase
BE1S18E01_00470	COG5487	UPF0391 membrane protein
BE1S18E01_00480	COG2983	Belongs to the UPF0260 family
BE1S18E01_00500	COG2133	pyrroloquinoline quinone binding
BE1S18E01_00510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BE1S18E01_00520	COG2116	formate transmembrane transporter activity
BE1S18E01_00560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE1S18E01_00570	COG1335	isochorismatase
BE1S18E01_00580	COG0385	Bile acid
BE1S18E01_00590	COG0534	Mate efflux family protein
BE1S18E01_00600	COG1683	Conserved Protein
BE1S18E01_00630	COG0346	lactoylglutathione lyase activity
BE1S18E01_00640	COG0625	glutathione transferase activity
BE1S18E01_00660	COG1113	amino acid transport
BE1S18E01_00680	COG0523	cobalamin synthesis protein
BE1S18E01_00700	COG2188	Transcriptional regulator
BE1S18E01_00760	COG0010	Belongs to the arginase family
BE1S18E01_00880	COG0546	phosphoglycolate phosphatase activity
BE1S18E01_00890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BE1S18E01_00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BE1S18E01_00930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BE1S18E01_00940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BE1S18E01_01140	COG0534	Mate efflux family protein
BE1S18E01_01150	COG0436	Aminotransferase
BE1S18E01_01160	COG2733	membrane
BE1S18E01_01190	COG2918	glutathione biosynthetic process
BE1S18E01_01210	COG3501	Rhs element vgr protein
BE1S18E01_01220	COG1388	LysM domain
BE1S18E01_01220	COG1705	Flagellar rod assembly protein muramidase FlgJ
BE1S18E01_01260	COG3150	esterase
BE1S18E01_01280	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BE1S18E01_01300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BE1S18E01_01320	COG2233	PERMEase
BE1S18E01_01330	COG2351	hydroxyisourate hydrolase activity
BE1S18E01_01400	COG3706	GGDEF domain
BE1S18E01_01430	COG1393	Belongs to the ArsC family
BE1S18E01_01440	COG0708	Exodeoxyribonuclease III
BE1S18E01_01510	COG0189	ligase activity
BE1S18E01_01550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BE1S18E01_01570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BE1S18E01_01600	COG4942	peptidase
BE1S18E01_01620	COG0508	dehydrogenase complex catalyzes the overall conversion of
BE1S18E01_01640	COG2119	membrane
BE1S18E01_01650	COG4774	siderophore transport
BE1S18E01_01660	COG0426	domain, Protein
BE1S18E01_01660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE1S18E01_01700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BE1S18E01_01740	COG1902	pentaerythritol trinitrate reductase activity
BE1S18E01_01750	COG1519	Transferase
BE1S18E01_01760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BE1S18E01_01770	COG0668	transmembrane transport
BE1S18E01_01790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BE1S18E01_01800	COG1335	isochorismatase
BE1S18E01_01810	COG1522	sequence-specific DNA binding
BE1S18E01_01860	COG0784	Response regulator, receiver
BE1S18E01_01860	COG2198	Histidine kinase
BE1S18E01_01860	COG2205	protein histidine kinase activity
BE1S18E01_01870	COG3162	membrane
BE1S18E01_01880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BE1S18E01_01900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE1S18E01_01920	COG3706	GGDEF domain
BE1S18E01_01940	COG1309	transcriptional regulator
BE1S18E01_01980	COG0300	oxidoreductase activity
BE1S18E01_01990	COG0789	Transcriptional regulator
BE1S18E01_02000	COG0351	phosphomethylpyrimidine kinase
BE1S18E01_02000	COG0352	thiamine-phosphate diphosphorylase activity
BE1S18E01_02000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BE1S18E01_02020	COG2814	Major facilitator Superfamily
BE1S18E01_02050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BE1S18E01_02070	COG1113	amino acid transport
BE1S18E01_02090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BE1S18E01_02100	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_02120	COG1335	isochorismatase
BE1S18E01_02180	COG2814	Major facilitator Superfamily
BE1S18E01_02190	COG0583	DNA-binding transcription factor activity
BE1S18E01_02230	COG0667	Aldo Keto reductase
BE1S18E01_02300	COG1733	regulation of RNA biosynthetic process
BE1S18E01_02310	COG2249	NAD(P)H dehydrogenase (quinone) activity
BE1S18E01_02440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BE1S18E01_02470	COG2329	Antibiotic biosynthesis monooxygenase
BE1S18E01_02480	COG0697	spore germination
BE1S18E01_02510	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BE1S18E01_02530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BE1S18E01_02570	COG0427	acetyl-CoA hydrolase
BE1S18E01_02580	COG2205	protein histidine kinase activity
BE1S18E01_02590	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_02610	COG0659	secondary active sulfate transmembrane transporter activity
BE1S18E01_02620	COG4221	oxidoreductase activity
BE1S18E01_02630	COG2873	o-acetylhomoserine
BE1S18E01_02640	COG0488	(ABC) transporter
BE1S18E01_02790	COG0833	amino acid
BE1S18E01_02860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BE1S18E01_02870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BE1S18E01_02900	COG2226	methyltransferase
BE1S18E01_03000	COG0067	glutamate synthase
BE1S18E01_03000	COG0070	glutamate synthase
BE1S18E01_03000	COG0069	glutamate synthase activity
BE1S18E01_03010	COG0493	'glutamate synthase
BE1S18E01_03030	COG1704	LemA family
BE1S18E01_03040	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BE1S18E01_03080	COG3307	-O-antigen
BE1S18E01_03120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BE1S18E01_03140	COG0194	GDP metabolic process
BE1S18E01_03240	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BE1S18E01_03260	COG0335	large ribosomal subunit rRNA binding
BE1S18E01_03280	COG5380	lipid catabolic process
BE1S18E01_03290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BE1S18E01_03320	COG5006	permease, DMT superfamily
BE1S18E01_03340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BE1S18E01_03350	COG0277	FAD linked oxidase domain protein
BE1S18E01_03370	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BE1S18E01_03380	COG2249	NAD(P)H dehydrogenase (quinone) activity
BE1S18E01_03410	COG1289	transmembrane transporter activity
BE1S18E01_03430	COG0628	permease
BE1S18E01_03500	COG0833	amino acid
BE1S18E01_03510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BE1S18E01_03520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BE1S18E01_03540	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_03620	COG0583	DNA-binding transcription factor activity
BE1S18E01_03670	COG0752	glycyl-tRNA synthetase alpha subunit
BE1S18E01_03720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BE1S18E01_03720	COG0517	IMP dehydrogenase activity
BE1S18E01_03720	COG0617	tRNA 3'-terminal CCA addition
BE1S18E01_03730	COG1983	PspC domain protein
BE1S18E01_03750	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_03780	COG0408	coproporphyrinogen oxidase activity
BE1S18E01_03820	COG0513	Belongs to the DEAD box helicase family
BE1S18E01_03830	COG1127	ABC transporter
BE1S18E01_03840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BE1S18E01_03860	COG2854	intermembrane phospholipid transfer
BE1S18E01_03880	COG0598	Magnesium transport protein CorA
BE1S18E01_03900	COG0494	nUDIX hydrolase
BE1S18E01_03910	COG1040	competence protein
BE1S18E01_03920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BE1S18E01_03960	COG1946	Acyl-CoA thioesterase
BE1S18E01_03970	COG1301	dicarboxylic acid transport
BE1S18E01_04000	COG1959	2 iron, 2 sulfur cluster binding
BE1S18E01_04010	COG1017	nitric oxide dioxygenase activity
BE1S18E01_04010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BE1S18E01_04020	COG0433	COG0433 Predicted ATPase
BE1S18E01_04030	COG0626	cystathionine gamma-synthase activity
BE1S18E01_04060	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BE1S18E01_04070	COG0088	Forms part of the polypeptide exit tunnel
BE1S18E01_04340	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_04350	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BE1S18E01_04420	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BE1S18E01_04430	COG0339	signal peptide processing
BE1S18E01_04440	COG0557	exoribonuclease II activity
BE1S18E01_04490	COG0179	Fumarylacetoacetate (FAA) hydrolase
BE1S18E01_04500	COG1295	ribonuclease BN
BE1S18E01_04570	COG1702	phosphate starvation-inducible protein PhoH
BE1S18E01_04590	COG1196	nuclear chromosome segregation
BE1S18E01_04590	COG0739	heme binding
BE1S18E01_04590	COG0741	lytic transglycosylase activity
BE1S18E01_04650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BE1S18E01_04660	COG1183	phosphatidylcholine synthase activity
BE1S18E01_04700	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_04710	COG1309	transcriptional regulator
BE1S18E01_04740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BE1S18E01_04750	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_04830	COG2969	positive regulation of protein catabolic process
BE1S18E01_04850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BE1S18E01_04860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BE1S18E01_04870	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BE1S18E01_04880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BE1S18E01_04890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BE1S18E01_04930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BE1S18E01_04950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BE1S18E01_04960	COG1408	metallophosphoesterase
BE1S18E01_04970	COG2885	chlorophyll binding
BE1S18E01_04970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BE1S18E01_04980	COG2199	diguanylate cyclase activity
BE1S18E01_05060	COG1607	acyl-coa hydrolase
BE1S18E01_05130	COG2350	Protein conserved in bacteria
BE1S18E01_05160	COG3781	membrane
BE1S18E01_05180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BE1S18E01_05190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BE1S18E01_05210	COG1862	Preprotein translocase
BE1S18E01_05290	COG0784	Response regulator, receiver
BE1S18E01_05290	COG2205	protein histidine kinase activity
BE1S18E01_05290	COG5002	protein histidine kinase activity
BE1S18E01_05300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BE1S18E01_05330	COG0726	polysaccharide deacetylase
BE1S18E01_05360	COG1216	Glycosyl transferase, family 2
BE1S18E01_05460	COG0625	glutathione transferase activity
BE1S18E01_05470	COG0583	DNA-binding transcription factor activity
BE1S18E01_05480	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_05490	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_05510	COG2205	protein histidine kinase activity
BE1S18E01_05520	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_05540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BE1S18E01_05580	COG2096	Adenosyltransferase
BE1S18E01_05590	COG4206	TonB-dependent receptor
BE1S18E01_05680	COG0285	dihydrofolate synthase activity
BE1S18E01_05720	COG0450	alkyl hydroperoxide reductase
BE1S18E01_05750	COG0477	Major facilitator Superfamily
BE1S18E01_05760	COG1272	protein, Hemolysin III
BE1S18E01_05780	COG2153	protein acetylation
BE1S18E01_05820	COG0183	Belongs to the thiolase family
BE1S18E01_05830	COG2207	Transcriptional regulator
BE1S18E01_05870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BE1S18E01_05910	COG0183	Belongs to the thiolase family
BE1S18E01_05930	COG2885	chlorophyll binding
BE1S18E01_05930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BE1S18E01_05960	COG1690	Belongs to the RtcB family
BE1S18E01_05970	COG0833	amino acid
BE1S18E01_05990	COG2233	PERMEase
BE1S18E01_06050	COG2094	Belongs to the DNA glycosylase MPG family
BE1S18E01_06060	COG4772	TonB-dependent receptor
BE1S18E01_06070	COG1902	pentaerythritol trinitrate reductase activity
BE1S18E01_06080	COG0679	Auxin Efflux Carrier
BE1S18E01_06100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BE1S18E01_06110	COG0354	folic acid binding
BE1S18E01_06140	COG2233	PERMEase
BE1S18E01_06150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE1S18E01_06160	COG0251	oxidation-reduction process
BE1S18E01_06170	COG1335	isochorismatase
BE1S18E01_06180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE1S18E01_06190	COG0778	Nitroreductase
BE1S18E01_06200	COG0596	Alpha beta hydrolase
BE1S18E01_06210	COG3189	MarR family transcriptional regulator
BE1S18E01_06220	COG2824	Alkylphosphonate utilization operon protein PhnA
BE1S18E01_06230	COG3422	double-strand break repair
BE1S18E01_06310	COG0840	transmembrane signaling receptor activity
BE1S18E01_06360	COG5510	response to toxic substance
BE1S18E01_06380	COG2832	Protein of unknown function (DUF454)
BE1S18E01_06390	COG1376	ErfK ybiS ycfS ynhG family protein
BE1S18E01_06410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BE1S18E01_06430	COG1289	transmembrane transporter activity
BE1S18E01_06440	COG2814	Major facilitator Superfamily
BE1S18E01_06470	COG1115	amino acid carrier protein
BE1S18E01_06480	COG1752	Esterase of the alpha-beta hydrolase superfamily
BE1S18E01_06490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BE1S18E01_06500	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BE1S18E01_06510	COG3590	peptidase
BE1S18E01_06560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BE1S18E01_06580	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BE1S18E01_06590	COG1077	Cell shape determining protein MreB Mrl
BE1S18E01_06600	COG1792	Involved in formation and maintenance of cell shape
BE1S18E01_06610	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BE1S18E01_06620	COG0424	maF-like protein
BE1S18E01_06630	COG1530	ribonuclease E activity
BE1S18E01_06650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BE1S18E01_06690	COG2249	NAD(P)H dehydrogenase (quinone) activity
BE1S18E01_06740	COG2207	Transcriptional regulator
BE1S18E01_06770	COG3328	transposase activity
BE1S18E01_06790	COG0464	growth
BE1S18E01_06890	COG0305	Participates in initiation and elongation during chromosome replication
BE1S18E01_06970	COG0582	viral genome integration into host DNA
BE1S18E01_06990	COG3046	protein related to deoxyribodipyrimidine photolyase
BE1S18E01_07010	COG1113	amino acid transport
BE1S18E01_07020	COG2828	Protein conserved in bacteria
BE1S18E01_07030	COG0142	geranyltranstransferase activity
BE1S18E01_07040	COG2315	Protein conserved in bacteria
BE1S18E01_07070	COG1752	Esterase of the alpha-beta hydrolase superfamily
BE1S18E01_07110	COG2194	sulfuric ester hydrolase activity
BE1S18E01_07120	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_07130	COG0642	Histidine kinase
BE1S18E01_07150	COG0004	ammonium transporteR
BE1S18E01_07160	COG0583	DNA-binding transcription factor activity
BE1S18E01_07200	COG0525	valine-tRNA ligase activity
BE1S18E01_07220	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_07240	COG0393	Putative heavy-metal-binding
BE1S18E01_07250	COG0393	Putative heavy-metal-binding
BE1S18E01_07260	COG1538	Outer membrane efflux protein
BE1S18E01_07280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_07290	COG0671	phosphoesterase, PA-phosphatase related
BE1S18E01_07340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BE1S18E01_07370	COG1648	precorrin-2 dehydrogenase activity
BE1S18E01_07370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BE1S18E01_07380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BE1S18E01_07450	COG0531	amino acid
BE1S18E01_07480	COG0321	lipoyl(octanoyl) transferase activity
BE1S18E01_07490	COG2921	Belongs to the UPF0250 family
BE1S18E01_07570	COG2009	succinate dehydrogenase
BE1S18E01_07580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BE1S18E01_07590	COG1053	succinate dehydrogenase
BE1S18E01_07600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BE1S18E01_07630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BE1S18E01_07670	COG2354	Protein conserved in bacteria
BE1S18E01_07680	COG2321	neutral zinc metallopeptidase
BE1S18E01_07720	COG2843	Capsule synthesis protein
BE1S18E01_07760	COG0589	response to stress
BE1S18E01_07780	COG0251	oxidation-reduction process
BE1S18E01_07790	COG1309	transcriptional regulator
BE1S18E01_07820	COG0505	Belongs to the CarA family
BE1S18E01_07870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BE1S18E01_07880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BE1S18E01_07950	COG0477	Major facilitator Superfamily
BE1S18E01_07960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BE1S18E01_07990	COG1597	lipid kinase activity
BE1S18E01_08000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BE1S18E01_08060	COG0584	glycerophosphoryl diester phosphodiesterase
BE1S18E01_08100	COG0741	lytic transglycosylase activity
BE1S18E01_08140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BE1S18E01_08150	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_08170	COG0583	DNA-binding transcription factor activity
BE1S18E01_08220	COG0406	alpha-ribazole phosphatase activity
BE1S18E01_08260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_08280	COG0778	Nitroreductase
BE1S18E01_08310	COG1929	Belongs to the glycerate kinase type-1 family
BE1S18E01_08320	COG0243	molybdopterin cofactor binding
BE1S18E01_08330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BE1S18E01_08360	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BE1S18E01_08390	COG1115	amino acid carrier protein
BE1S18E01_08400	COG1113	amino acid transport
BE1S18E01_08420	COG0019	diaminopimelate decarboxylase activity
BE1S18E01_08440	COG1280	lysine exporter protein (LysE YggA)
BE1S18E01_08450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BE1S18E01_08510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_08570	COG4591	ABC-type transport system involved in lipoprotein release permease component
BE1S18E01_08580	COG1136	(ABC) transporter
BE1S18E01_08590	COG0658	competence protein
BE1S18E01_08590	COG2333	competence protein COMEC
BE1S18E01_08610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BE1S18E01_08610	COG0616	signal peptide processing
BE1S18E01_08620	COG0596	Alpha beta hydrolase
BE1S18E01_08630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BE1S18E01_08650	COG0628	permease
BE1S18E01_08720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BE1S18E01_08760	COG0823	Involved in the tonB-independent uptake of proteins
BE1S18E01_08800	COG0824	Thioesterase
BE1S18E01_08810	COG1473	amidohydrolase
BE1S18E01_08850	COG0047	phosphoribosylformylglycinamidine synthase activity
BE1S18E01_08850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BE1S18E01_08860	COG2814	Major facilitator Superfamily
BE1S18E01_08880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BE1S18E01_08890	COG1024	Enoyl-CoA hydratase
BE1S18E01_08900	COG1051	belongs to the nudix hydrolase family
BE1S18E01_08900	COG1056	cytidyltransferase-related domain
BE1S18E01_08930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BE1S18E01_08960	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BE1S18E01_08990	COG4625	pathogenesis
BE1S18E01_09000	COG0583	DNA-binding transcription factor activity
BE1S18E01_09010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BE1S18E01_09020	COG4208	sulfate ABC transporter
BE1S18E01_09030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BE1S18E01_09050	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BE1S18E01_09060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BE1S18E01_09070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BE1S18E01_09110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BE1S18E01_09130	COG0481	GTPase activity
BE1S18E01_09140	COG0681	Belongs to the peptidase S26 family
BE1S18E01_09160	COG0571	ribonuclease III activity
BE1S18E01_09170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BE1S18E01_09190	COG1381	Involved in DNA repair and RecF pathway recombination
BE1S18E01_09200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BE1S18E01_09220	COG4221	oxidoreductase activity
BE1S18E01_09260	COG0436	Aminotransferase
BE1S18E01_09300	COG0556	nucleotide-excision repair
BE1S18E01_09320	COG2962	Rard protein
BE1S18E01_09410	COG2070	2-Nitropropane dioxygenase
BE1S18E01_09440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BE1S18E01_09470	COG1215	transferase activity, transferring glycosyl groups
BE1S18E01_09500	COG0415	Belongs to the DNA photolyase family
BE1S18E01_09520	COG1252	NADH dehydrogenase
BE1S18E01_09530	COG1686	Belongs to the peptidase S11 family
BE1S18E01_09560	COG1187	pseudouridine synthase activity
BE1S18E01_09580	COG0477	Major facilitator Superfamily
BE1S18E01_09590	COG0583	DNA-binding transcription factor activity
BE1S18E01_09620	COG0612	Peptidase, M16
BE1S18E01_09670	COG0352	thiamine-phosphate diphosphorylase activity
BE1S18E01_09740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BE1S18E01_09770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BE1S18E01_09780	COG0076	glutamate decarboxylase activity
BE1S18E01_09800	COG1522	sequence-specific DNA binding
BE1S18E01_09810	COG3961	Belongs to the TPP enzyme family
BE1S18E01_09820	COG1113	amino acid transport
BE1S18E01_09830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BE1S18E01_09840	COG0573	inorganic phosphate transmembrane transporter activity
BE1S18E01_09860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BE1S18E01_09870	COG0616	signal peptide processing
BE1S18E01_09950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BE1S18E01_09960	COG1686	Belongs to the peptidase S11 family
BE1S18E01_10010	COG0583	DNA-binding transcription factor activity
BE1S18E01_10020	COG1067	ATP-dependent peptidase activity
BE1S18E01_10030	COG2211	Major facilitator Superfamily
BE1S18E01_10100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BE1S18E01_10110	COG1966	Carbon starvation protein
BE1S18E01_10120	COG2879	small protein
BE1S18E01_10160	COG1741	Belongs to the pirin family
BE1S18E01_10190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BE1S18E01_10220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BE1S18E01_10230	COG4605	iron ion homeostasis
BE1S18E01_10240	COG4604	ABC transporter, ATP-binding protein
BE1S18E01_10250	COG4607	ABC-type enterochelin transport system periplasmic component
BE1S18E01_10260	COG4774	siderophore transport
BE1S18E01_10280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BE1S18E01_10290	COG1021	2,3-dihydroxybenzoate-AMP ligase
BE1S18E01_10300	COG3433	isochorismatase activity
BE1S18E01_10300	COG1535	isochorismatase
BE1S18E01_10320	COG1132	(ABC) transporter
BE1S18E01_10340	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BE1S18E01_10360	COG1169	isochorismate synthase
BE1S18E01_10390	COG3739	integral membrane protein
BE1S18E01_10450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BE1S18E01_10470	COG2840	Smr protein MutS2
BE1S18E01_10520	COG0512	Glutamine amidotransferase of anthranilate synthase
BE1S18E01_10540	COG3104	oligopeptide transport
BE1S18E01_10550	COG0174	glutamine synthetase
BE1S18E01_10570	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BE1S18E01_10610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BE1S18E01_10620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BE1S18E01_10630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BE1S18E01_10670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BE1S18E01_10680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BE1S18E01_10690	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BE1S18E01_10720	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_10730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BE1S18E01_10740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BE1S18E01_10770	COG2223	nitrite transmembrane transporter activity
BE1S18E01_10790	COG0024	Methionine aminopeptidase
BE1S18E01_10800	COG0052	Belongs to the universal ribosomal protein uS2 family
BE1S18E01_10830	COG2207	Transcriptional regulator
BE1S18E01_10880	COG2951	lytic endotransglycosylase activity
BE1S18E01_10890	COG0772	Belongs to the SEDS family
BE1S18E01_10920	COG0842	Transport permease protein
BE1S18E01_10930	COG1131	(ABC) transporter
BE1S18E01_11000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_11020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE1S18E01_11030	COG4215	(ABC) transporter
BE1S18E01_11040	COG4160	amino acid transport
BE1S18E01_11050	COG4598	ABC transporter
BE1S18E01_11070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BE1S18E01_11090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_11100	COG0384	phenazine biosynthesis protein PhzF
BE1S18E01_11120	COG1720	tRNA m6t6A37 methyltransferase activity
BE1S18E01_11160	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_11170	COG0642	Histidine kinase
BE1S18E01_11190	COG0494	nUDIX hydrolase
BE1S18E01_11210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BE1S18E01_11220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BE1S18E01_11230	COG3139	Protein of unknown function (DUF1315)
BE1S18E01_11240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BE1S18E01_11250	COG1301	dicarboxylic acid transport
BE1S18E01_11260	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_11290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BE1S18E01_11310	COG2195	Cleaves the N-terminal amino acid of tripeptides
BE1S18E01_11320	COG1234	tRNA 3'-trailer cleavage
BE1S18E01_11370	COG2363	Small membrane protein
BE1S18E01_11410	COG0513	Belongs to the DEAD box helicase family
BE1S18E01_11430	COG0778	Nitroreductase
BE1S18E01_11490	COG1286	toxin biosynthetic process
BE1S18E01_11540	COG4783	chaperone-mediated protein folding
BE1S18E01_11550	COG1610	YqeY-like protein
BE1S18E01_11610	COG0515	serine threonine protein kinase
BE1S18E01_11610	COG2815	serine threonine protein kinase
BE1S18E01_11620	COG1278	Cold shock
BE1S18E01_11650	COG3243	poly(R)-hydroxyalkanoic acid synthase
BE1S18E01_11660	COG0786	glutamate:sodium symporter activity
BE1S18E01_11670	COG0475	glutathione-regulated potassium exporter activity
BE1S18E01_11670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BE1S18E01_11680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BE1S18E01_11680	COG0475	glutathione-regulated potassium exporter activity
BE1S18E01_11750	COG2985	domain, Protein
BE1S18E01_11770	COG2995	paraquat-inducible protein a
BE1S18E01_11780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BE1S18E01_11780	COG3008	intermembrane lipid transfer
BE1S18E01_11830	COG2351	hydroxyisourate hydrolase activity
BE1S18E01_11910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BE1S18E01_11930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BE1S18E01_11940	COG0642	Histidine kinase
BE1S18E01_11950	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_11980	COG1794	racemase activity, acting on amino acids and derivatives
BE1S18E01_12000	COG2175	clavaminate synthase activity
BE1S18E01_12010	COG3246	L-lysine catabolic process to acetate
BE1S18E01_12020	COG2814	Major facilitator Superfamily
BE1S18E01_12050	COG2855	membrane
BE1S18E01_12120	COG2814	Major facilitator Superfamily
BE1S18E01_12170	COG1301	dicarboxylic acid transport
BE1S18E01_12190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BE1S18E01_12200	COG2011	ABC-type metal ion transport system permease component
BE1S18E01_12210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BE1S18E01_12230	COG0151	Belongs to the GarS family
BE1S18E01_12250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BE1S18E01_12310	COG2308	Evidence 4 Homologs of previously reported genes of
BE1S18E01_12330	COG1305	Transglutaminase-like
BE1S18E01_12350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BE1S18E01_12360	COG0305	Participates in initiation and elongation during chromosome replication
BE1S18E01_12410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BE1S18E01_12420	COG1845	cytochrome c oxidase, subunit III
BE1S18E01_12430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BE1S18E01_12490	COG1649	PFAM Uncharacterised BCR, COG1649
BE1S18E01_12490	COG0726	polysaccharide deacetylase
BE1S18E01_12500	COG1215	transferase activity, transferring glycosyl groups
BE1S18E01_12510	COG3658	cytochrome
BE1S18E01_12530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE1S18E01_12560	COG0583	DNA-binding transcription factor activity
BE1S18E01_12590	COG2890	protein-(glutamine-N5) methyltransferase activity
BE1S18E01_12600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BE1S18E01_12610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BE1S18E01_12640	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_12650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE1S18E01_12680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BE1S18E01_12700	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BE1S18E01_12710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BE1S18E01_12730	COG2205	protein histidine kinase activity
BE1S18E01_12740	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_12750	COG0174	glutamine synthetase
BE1S18E01_12780	COG0477	Major facilitator Superfamily
BE1S18E01_12790	COG0729	surface antigen
BE1S18E01_12860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BE1S18E01_12870	COG2814	Major facilitator Superfamily
BE1S18E01_12900	COG0583	DNA-binding transcription factor activity
BE1S18E01_12930	COG1187	pseudouridine synthase activity
BE1S18E01_12960	COG0564	pseudouridine synthase activity
BE1S18E01_12970	COG0802	atpase or kinase
BE1S18E01_12980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BE1S18E01_13000	COG1923	regulation of RNA biosynthetic process
BE1S18E01_13010	COG0697	spore germination
BE1S18E01_13040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BE1S18E01_13060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BE1S18E01_13070	COG0519	Catalyzes the synthesis of GMP from XMP
BE1S18E01_13070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BE1S18E01_13080	COG4302	ethanolamine ammonia-lyase activity
BE1S18E01_13090	COG4303	Ethanolamine ammonia lyase large subunit
BE1S18E01_13100	COG0531	amino acid
BE1S18E01_13150	COG1454	alcohol dehydrogenase
BE1S18E01_13160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BE1S18E01_13230	COG0308	aminopeptidase N
BE1S18E01_13310	COG1605	Chorismate mutase
BE1S18E01_13340	COG4772	TonB-dependent receptor
BE1S18E01_13350	COG4774	siderophore transport
BE1S18E01_13460	COG3772	lysozyme
BE1S18E01_13510	COG0583	DNA-binding transcription factor activity
BE1S18E01_13570	COG0488	(ABC) transporter
BE1S18E01_13580	COG0589	response to stress
BE1S18E01_13620	COG3135	benzoate transporter
BE1S18E01_13630	COG1522	sequence-specific DNA binding
BE1S18E01_13650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BE1S18E01_13660	COG0583	DNA-binding transcription factor activity
BE1S18E01_13680	COG0183	Belongs to the thiolase family
BE1S18E01_13700	COG2030	dehydratase
BE1S18E01_13760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BE1S18E01_13780	COG0824	Thioesterase
BE1S18E01_13790	COG1454	alcohol dehydrogenase
BE1S18E01_13840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BE1S18E01_13900	COG0069	glutamate synthase activity
BE1S18E01_13970	COG2814	Major facilitator Superfamily
BE1S18E01_14000	COG0511	ligase activity, forming carbon-carbon bonds
BE1S18E01_14050	COG4264	IucA IucC family
BE1S18E01_14070	COG4264	IucA IucC family
BE1S18E01_14080	COG2423	ornithine cyclodeaminase activity
BE1S18E01_14090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BE1S18E01_14100	COG1116	anion transmembrane transporter activity
BE1S18E01_14100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BE1S18E01_14130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BE1S18E01_14130	COG2146	nitrite reductase [NAD(P)H] activity
BE1S18E01_14140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BE1S18E01_14150	COG0243	molybdopterin cofactor binding
BE1S18E01_14170	COG0243	molybdopterin cofactor binding
BE1S18E01_14180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BE1S18E01_14210	COG0315	cyclic pyranopterin monophosphate synthase activity
BE1S18E01_14210	COG0521	Mo-molybdopterin cofactor biosynthetic process
BE1S18E01_14220	COG0303	'Molybdopterin
BE1S18E01_14240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_14250	COG0697	spore germination
BE1S18E01_14300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BE1S18E01_14430	COG2204	response regulator
BE1S18E01_14440	COG3852	Histidine kinase
BE1S18E01_14480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BE1S18E01_14490	COG0575	Belongs to the CDS family
BE1S18E01_14560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BE1S18E01_14580	COG2137	regulation of response to DNA damage stimulus
BE1S18E01_14600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BE1S18E01_14610	COG1011	Hydrolase
BE1S18E01_14640	COG1522	sequence-specific DNA binding
BE1S18E01_14660	COG1113	amino acid transport
BE1S18E01_14700	COG0659	secondary active sulfate transmembrane transporter activity
BE1S18E01_14830	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BE1S18E01_14830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BE1S18E01_14830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BE1S18E01_14840	COG1105	Belongs to the carbohydrate kinase PfkB family
BE1S18E01_14850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE1S18E01_14850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BE1S18E01_14890	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BE1S18E01_14910	COG0024	Methionine aminopeptidase
BE1S18E01_14920	COG0583	DNA-binding transcription factor activity
BE1S18E01_14940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BE1S18E01_14950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BE1S18E01_14960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BE1S18E01_14960	COG0517	IMP dehydrogenase activity
BE1S18E01_15010	COG0552	protein localization to endoplasmic reticulum
BE1S18E01_15030	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BE1S18E01_15060	COG4890	Cyd operon protein YbgT
BE1S18E01_15070	COG1294	oxidase, subunit
BE1S18E01_15100	COG1585	Membrane protein implicated in regulation of membrane protease activity
BE1S18E01_15120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE1S18E01_15150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BE1S18E01_15160	COG0569	domain protein
BE1S18E01_15170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BE1S18E01_15230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BE1S18E01_15240	COG0542	response to heat
BE1S18E01_15290	COG1902	pentaerythritol trinitrate reductase activity
BE1S18E01_15290	COG0446	pyridine nucleotide-disulphide oxidoreductase
BE1S18E01_15370	COG0148	phosphopyruvate hydratase activity
BE1S18E01_15380	COG2323	membrane
BE1S18E01_15400	COG4773	Receptor
BE1S18E01_15410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BE1S18E01_15430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BE1S18E01_15440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BE1S18E01_15450	COG0183	Belongs to the thiolase family
BE1S18E01_15460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BE1S18E01_15470	COG0596	Alpha beta hydrolase
BE1S18E01_15480	COG2271	Major facilitator Superfamily
BE1S18E01_15490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BE1S18E01_15500	COG3485	protocatechuate 3,4-dioxygenase
BE1S18E01_15510	COG3485	protocatechuate 3,4-dioxygenase
BE1S18E01_15520	COG0710	3-dehydroquinate dehydratase activity
BE1S18E01_15530	COG3420	alginic acid biosynthetic process
BE1S18E01_15540	COG3659	wide pore channel activity
BE1S18E01_15550	COG4993	Dehydrogenase
BE1S18E01_15570	COG2391	methyltransferase activity
BE1S18E01_15600	COG1414	Transcriptional regulator
BE1S18E01_15610	COG0583	DNA-binding transcription factor activity
BE1S18E01_15620	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_15670	COG2814	Major facilitator Superfamily
BE1S18E01_15690	COG0154	amidase activity
BE1S18E01_15730	COG4638	Rieske (2fe-2S)
BE1S18E01_15750	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_15770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE1S18E01_15810	COG3733	amine oxidase
BE1S18E01_15830	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_15840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BE1S18E01_15850	COG0183	Belongs to the thiolase family
BE1S18E01_15860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BE1S18E01_15870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BE1S18E01_15890	COG4829	muconolactone delta-isomerase
BE1S18E01_15900	COG4948	Mandelate Racemase Muconate Lactonizing
BE1S18E01_15910	COG0583	DNA-binding transcription factor activity
BE1S18E01_15940	COG2186	Transcriptional regulator
BE1S18E01_15980	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_15990	COG2351	hydroxyisourate hydrolase activity
BE1S18E01_16000	COG2233	PERMEase
BE1S18E01_16020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BE1S18E01_16030	COG2186	Transcriptional regulator
BE1S18E01_16050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BE1S18E01_16070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BE1S18E01_16110	COG0446	pyridine nucleotide-disulphide oxidoreductase
BE1S18E01_16110	COG1902	pentaerythritol trinitrate reductase activity
BE1S18E01_16190	COG1309	transcriptional regulator
BE1S18E01_16200	COG0583	DNA-binding transcription factor activity
BE1S18E01_16210	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_16220	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_16230	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_16250	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_16270	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_16330	COG0583	DNA-binding transcription factor activity
BE1S18E01_16380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BE1S18E01_16390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BE1S18E01_16480	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_16490	COG0129	dihydroxy-acid dehydratase activity
BE1S18E01_16510	COG0583	DNA-binding transcription factor activity
BE1S18E01_16520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BE1S18E01_16540	COG2084	Dehydrogenase
BE1S18E01_16580	COG1120	ATPase activity
BE1S18E01_16620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BE1S18E01_16720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BE1S18E01_16770	COG2856	Zn peptidase
BE1S18E01_16840	COG2207	Transcriptional regulator
BE1S18E01_16870	COG3539	Fimbrial protein
BE1S18E01_16920	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BE1S18E01_16940	COG0753	catalase activity
BE1S18E01_16970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BE1S18E01_16990	COG2205	protein histidine kinase activity
BE1S18E01_17000	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_17010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_17020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BE1S18E01_17120	COG1535	isochorismatase
BE1S18E01_17120	COG3433	isochorismatase activity
BE1S18E01_17130	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_17140	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BE1S18E01_17150	COG4149	molybdate abc transporter
BE1S18E01_17160	COG0725	ABC transporter, periplasmic molybdate-binding protein
BE1S18E01_17180	COG4638	Rieske (2fe-2S)
BE1S18E01_17190	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BE1S18E01_17200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BE1S18E01_17200	COG0543	2 iron, 2 sulfur cluster binding
BE1S18E01_17230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE1S18E01_17250	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_17280	COG2207	Transcriptional regulator
BE1S18E01_17290	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_17300	COG2610	gluconate transmembrane transporter activity
BE1S18E01_17350	COG0583	DNA-binding transcription factor activity
BE1S18E01_17380	COG2031	fatty acid transporter
BE1S18E01_17390	COG0183	Belongs to the thiolase family
BE1S18E01_17400	COG0583	DNA-binding transcription factor activity
BE1S18E01_17410	COG0583	DNA-binding transcription factor activity
BE1S18E01_17440	COG1027	Aspartate ammonia-lyase
BE1S18E01_17460	COG0477	Major facilitator Superfamily
BE1S18E01_17480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BE1S18E01_17490	COG1733	regulation of RNA biosynthetic process
BE1S18E01_17500	COG2207	Transcriptional regulator
BE1S18E01_17500	COG3708	Transcriptional regulator
BE1S18E01_17530	COG0730	response to heat
BE1S18E01_17570	COG3781	membrane
BE1S18E01_17580	COG1063	alcohol dehydrogenase
BE1S18E01_17600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BE1S18E01_17610	COG0508	dehydrogenase complex catalyzes the overall conversion of
BE1S18E01_17620	COG0022	dehydrogenase e1 component
BE1S18E01_17630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BE1S18E01_17640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BE1S18E01_17670	COG3706	GGDEF domain
BE1S18E01_17710	COG0133	tryptophan synthase activity
BE1S18E01_17730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BE1S18E01_17790	COG0583	DNA-binding transcription factor activity
BE1S18E01_17800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BE1S18E01_17820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BE1S18E01_17940	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BE1S18E01_17950	COG4773	Receptor
BE1S18E01_17980	COG0730	response to heat
BE1S18E01_17990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BE1S18E01_18030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BE1S18E01_18060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BE1S18E01_18080	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BE1S18E01_18110	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_18120	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_18130	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BE1S18E01_18140	COG2207	Transcriptional regulator
BE1S18E01_18150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BE1S18E01_18160	COG0776	regulation of translation
BE1S18E01_18210	COG0822	iron-sulfur transferase activity
BE1S18E01_18220	COG0316	Belongs to the HesB IscA family
BE1S18E01_18280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BE1S18E01_18320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BE1S18E01_18330	COG0702	epimerase
BE1S18E01_18420	COG0339	signal peptide processing
BE1S18E01_18430	COG4166	transmembrane transport
BE1S18E01_18510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BE1S18E01_18520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BE1S18E01_18550	COG2431	L-lysine efflux transmembrane transporter activity
BE1S18E01_18580	COG0776	regulation of translation
BE1S18E01_18710	COG0084	hydrolase, TatD family'
BE1S18E01_18750	COG1663	tetraacyldisaccharide 4'-kinase activity
BE1S18E01_18760	COG1132	(ABC) transporter
BE1S18E01_18780	COG0811	peptide transport
BE1S18E01_18790	COG1475	DNA binding
BE1S18E01_18800	COG1192	Involved in chromosome partitioning
BE1S18E01_18820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BE1S18E01_18830	COG3178	'Phosphotransferase
BE1S18E01_18850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BE1S18E01_18900	COG0424	maF-like protein
BE1S18E01_18910	COG2850	peptidyl-arginine hydroxylation
BE1S18E01_18930	COG0640	Transcriptional regulator
BE1S18E01_18950	COG3619	membrane
BE1S18E01_18980	COG3122	Protein conserved in bacteria
BE1S18E01_19000	COG1132	(ABC) transporter
BE1S18E01_19040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BE1S18E01_19050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BE1S18E01_19070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BE1S18E01_19070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BE1S18E01_19070	COG0506	proline dehydrogenase activity
BE1S18E01_19080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BE1S18E01_19110	COG3698	Phosphodiester glycosidase
BE1S18E01_19130	COG2353	YceI-like domain
BE1S18E01_19150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BE1S18E01_19240	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BE1S18E01_19240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BE1S18E01_19290	COG3539	Fimbrial protein
BE1S18E01_19350	COG0583	DNA-binding transcription factor activity
BE1S18E01_19360	COG0697	spore germination
BE1S18E01_19380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BE1S18E01_19400	COG0583	DNA-binding transcription factor activity
BE1S18E01_19420	COG1309	transcriptional regulator
BE1S18E01_19450	COG1522	sequence-specific DNA binding
BE1S18E01_19470	COG1126	abc transporter atp-binding protein
BE1S18E01_19480	COG0765	amino acid transport
BE1S18E01_19490	COG0765	amino acid transport
BE1S18E01_19550	COG1464	Belongs to the NlpA lipoprotein family
BE1S18E01_19570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BE1S18E01_19580	COG2011	ABC-type metal ion transport system permease component
BE1S18E01_19590	COG0012	GTP binding
BE1S18E01_19640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BE1S18E01_19710	COG2207	Transcriptional regulator
BE1S18E01_19710	COG1917	Cupin 2, conserved barrel domain protein
BE1S18E01_19720	COG0386	Belongs to the glutathione peroxidase family
BE1S18E01_19740	COG0436	Aminotransferase
BE1S18E01_19750	COG1301	dicarboxylic acid transport
BE1S18E01_19820	COG3634	alkyl hydroperoxide reductase activity
BE1S18E01_19850	COG0583	DNA-binding transcription factor activity
BE1S18E01_19860	COG0431	NADPH-dependent FMN reductase
BE1S18E01_19870	COG0798	PFAM Bile acid sodium symporter
BE1S18E01_19920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BE1S18E01_19940	COG0583	DNA-binding transcription factor activity
BE1S18E01_19960	COG1953	Uracil, thiamine, allantoin
BE1S18E01_19980	COG2175	clavaminate synthase activity
BE1S18E01_19990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BE1S18E01_20000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BE1S18E01_20010	COG4521	taurine ABC transporter
BE1S18E01_20030	COG0477	Major facilitator Superfamily
BE1S18E01_20070	COG1271	oxidase subunit
BE1S18E01_20080	COG1294	oxidase, subunit
BE1S18E01_20090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_20130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BE1S18E01_20170	COG3052	prosthetic group binding
BE1S18E01_20180	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BE1S18E01_20200	COG0583	DNA-binding transcription factor activity
BE1S18E01_20210	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_20220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BE1S18E01_20240	COG2814	Major facilitator Superfamily
BE1S18E01_20250	COG0300	oxidoreductase activity
BE1S18E01_20300	COG1346	cytolysis
BE1S18E01_20320	COG0583	DNA-binding transcription factor activity
BE1S18E01_20330	COG0625	glutathione transferase activity
BE1S18E01_20340	COG0625	glutathione transferase activity
BE1S18E01_20380	COG0583	DNA-binding transcription factor activity
BE1S18E01_20390	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_20410	COG1045	serine acetyltransferase
BE1S18E01_20420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BE1S18E01_20430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BE1S18E01_20440	COG1280	lysine exporter protein (LysE YggA)
BE1S18E01_20460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE1S18E01_20470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE1S18E01_20490	COG0765	amino acid transport
BE1S18E01_20500	COG0765	amino acid transport
BE1S18E01_20530	COG2205	protein histidine kinase activity
BE1S18E01_20530	COG0784	Response regulator, receiver
BE1S18E01_20570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BE1S18E01_20610	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_20710	COG0583	DNA-binding transcription factor activity
BE1S18E01_20740	COG2814	Major facilitator Superfamily
BE1S18E01_20770	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_20780	COG3328	transposase activity
BE1S18E01_20790	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_20800	COG1309	transcriptional regulator
BE1S18E01_20810	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_20820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BE1S18E01_20830	COG1024	Enoyl-CoA hydratase
BE1S18E01_20840	COG4770	biotin carboxylase activity
BE1S18E01_20860	COG0583	DNA-binding transcription factor activity
BE1S18E01_20890	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_20910	COG2814	Major facilitator Superfamily
BE1S18E01_20930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BE1S18E01_20940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BE1S18E01_20950	COG2814	Major facilitator Superfamily
BE1S18E01_20960	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_20970	COG1024	Enoyl-CoA hydratase
BE1S18E01_20980	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_20990	COG1250	3-hydroxyacyl-CoA dehydrogenase
BE1S18E01_21000	COG0183	Belongs to the thiolase family
BE1S18E01_21020	COG2814	Major facilitator Superfamily
BE1S18E01_21040	COG1024	Enoyl-CoA hydratase
BE1S18E01_21060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BE1S18E01_21070	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_21080	COG2814	Major facilitator Superfamily
BE1S18E01_21090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BE1S18E01_21100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BE1S18E01_21130	COG3842	ATPase activity
BE1S18E01_21140	COG1840	ABC-type Fe3 transport system, periplasmic component
BE1S18E01_21170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BE1S18E01_21180	COG1414	Transcriptional regulator
BE1S18E01_21200	COG0583	DNA-binding transcription factor activity
BE1S18E01_21240	COG2050	protein possibly involved in aromatic compounds catabolism
BE1S18E01_21260	COG3327	negative regulation of DNA-templated transcription, initiation
BE1S18E01_21270	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BE1S18E01_21280	COG0183	Belongs to the thiolase family
BE1S18E01_21290	COG1250	3-hydroxyacyl-CoA dehydrogenase
BE1S18E01_21300	COG1024	Enoyl-CoA hydratase
BE1S18E01_21310	COG1024	Enoyl-CoA hydratase
BE1S18E01_21320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BE1S18E01_21330	COG2151	metal-sulfur cluster biosynthetic enzyme
BE1S18E01_21340	COG3396	Phenylacetate-CoA oxygenase
BE1S18E01_21350	COG3460	Phenylacetate-CoA oxygenase
BE1S18E01_21360	COG3396	Phenylacetate-CoA oxygenase
BE1S18E01_21370	COG2030	dehydratase
BE1S18E01_21370	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_21380	COG1760	l-serine dehydratase
BE1S18E01_21420	COG0789	Transcriptional regulator
BE1S18E01_21440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BE1S18E01_21450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_21480	COG2807	transmembrane transport
BE1S18E01_21590	COG1116	anion transmembrane transporter activity
BE1S18E01_21620	COG0864	Transcriptional regulator
BE1S18E01_21640	COG1733	regulation of RNA biosynthetic process
BE1S18E01_21650	COG2249	NAD(P)H dehydrogenase (quinone) activity
BE1S18E01_21660	COG0439	Biotin carboxylase
BE1S18E01_21690	COG1063	alcohol dehydrogenase
BE1S18E01_21700	COG1250	3-hydroxyacyl-CoA dehydrogenase
BE1S18E01_21740	COG3328	transposase activity
BE1S18E01_21800	COG3210	domain, Protein
BE1S18E01_21810	COG2831	hemolysin activation secretion protein
BE1S18E01_21820	COG0038	chloride channel
BE1S18E01_21830	COG4770	biotin carboxylase activity
BE1S18E01_21870	COG1914	H( )-stimulated, divalent metal cation uptake system
BE1S18E01_21880	COG0583	DNA-binding transcription factor activity
BE1S18E01_21900	COG1595	DNA-templated transcription, initiation
BE1S18E01_21920	COG3220	belongs to the UPF0276 family
BE1S18E01_22020	COG0702	epimerase
BE1S18E01_22030	COG1733	regulation of RNA biosynthetic process
BE1S18E01_22060	COG1051	belongs to the nudix hydrolase family
BE1S18E01_22100	COG1595	DNA-templated transcription, initiation
BE1S18E01_22110	COG3712	iron ion homeostasis
BE1S18E01_22180	COG3038	cytochrome b561
BE1S18E01_22190	COG0753	catalase activity
BE1S18E01_22200	COG1733	regulation of RNA biosynthetic process
BE1S18E01_22220	COG1469	GTP cyclohydrolase I activity
BE1S18E01_22240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BE1S18E01_22270	COG1522	sequence-specific DNA binding
BE1S18E01_22280	COG0531	amino acid
BE1S18E01_22290	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BE1S18E01_22320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BE1S18E01_22350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BE1S18E01_22370	COG4122	O-methyltransferase activity
BE1S18E01_22390	COG0110	maltose O-acetyltransferase activity
BE1S18E01_22420	COG1137	ATPase activity
BE1S18E01_22430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BE1S18E01_22450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BE1S18E01_22510	COG0668	transmembrane transport
BE1S18E01_22590	COG1309	transcriptional regulator
BE1S18E01_22620	COG2226	methyltransferase
BE1S18E01_22670	COG1278	Cold shock
BE1S18E01_22680	COG1560	Kdo2-lipid A biosynthetic process
BE1S18E01_22690	COG1280	lysine exporter protein (LysE YggA)
BE1S18E01_22750	COG1570	exodeoxyribonuclease VII activity
BE1S18E01_22910	COG2871	sodium ion transport
BE1S18E01_22930	COG0583	DNA-binding transcription factor activity
BE1S18E01_22940	COG4638	Rieske (2fe-2S)
BE1S18E01_22950	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BE1S18E01_22960	COG0633	Ferredoxin
BE1S18E01_22960	COG0543	2 iron, 2 sulfur cluster binding
BE1S18E01_22970	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_22980	COG3135	benzoate transporter
BE1S18E01_22990	COG2814	Major facilitator Superfamily
BE1S18E01_23020	COG1643	Atp-dependent helicase
BE1S18E01_23070	COG3634	alkyl hydroperoxide reductase activity
BE1S18E01_23110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BE1S18E01_23130	COG0625	glutathione transferase activity
BE1S18E01_23150	COG2885	chlorophyll binding
BE1S18E01_23220	COG0542	response to heat
BE1S18E01_23250	COG1765	OsmC-like protein
BE1S18E01_23270	COG0667	Aldo Keto reductase
BE1S18E01_23300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BE1S18E01_23320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BE1S18E01_23340	COG0582	viral genome integration into host DNA
BE1S18E01_23360	COG2194	sulfuric ester hydrolase activity
BE1S18E01_23450	COG0739	heme binding
BE1S18E01_23450	COG0741	lytic transglycosylase activity
BE1S18E01_23450	COG1196	nuclear chromosome segregation
BE1S18E01_23480	COG1598	PFAM Uncharacterised protein family UPF0150
BE1S18E01_23700	COG0527	aspartate kinase activity
BE1S18E01_23720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BE1S18E01_23740	COG3038	cytochrome b561
BE1S18E01_23750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BE1S18E01_23760	COG2252	PERMEase
BE1S18E01_23780	COG1741	Belongs to the pirin family
BE1S18E01_23790	COG1309	transcriptional regulator
BE1S18E01_23820	COG2072	flavoprotein involved in K transport
BE1S18E01_23830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BE1S18E01_23890	COG1944	ATP diphosphatase activity
BE1S18E01_23930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BE1S18E01_23960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BE1S18E01_23990	COG2814	Major facilitator Superfamily
BE1S18E01_24000	COG1024	Enoyl-CoA hydratase
BE1S18E01_24010	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_24030	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_24080	COG2186	Transcriptional regulator
BE1S18E01_24090	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_24110	COG4948	Mandelate Racemase Muconate Lactonizing
BE1S18E01_24120	COG2271	Major facilitator Superfamily
BE1S18E01_24130	COG2721	sulfolactate sulfo-lyase activity
BE1S18E01_24140	COG0697	spore germination
BE1S18E01_24190	COG1113	amino acid transport
BE1S18E01_24260	COG4269	membrane
BE1S18E01_24290	COG0582	viral genome integration into host DNA
BE1S18E01_24340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BE1S18E01_24400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BE1S18E01_24490	COG0789	Transcriptional regulator
BE1S18E01_24610	COG2059	Chromate
BE1S18E01_24640	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BE1S18E01_24670	COG1230	cation diffusion facilitator family transporter
BE1S18E01_24710	COG2814	Major facilitator Superfamily
BE1S18E01_24830	COG3328	transposase activity
BE1S18E01_24940	COG0582	viral genome integration into host DNA
BE1S18E01_24950	COG0446	pyridine nucleotide-disulphide oxidoreductase
BE1S18E01_24950	COG1902	pentaerythritol trinitrate reductase activity
BE1S18E01_24970	COG4251	negative regulation of phosphorylation
BE1S18E01_24970	COG5001	Diguanylate cyclase
BE1S18E01_24970	COG3706	GGDEF domain
BE1S18E01_24970	COG2203	Gaf domain
BE1S18E01_24990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BE1S18E01_25030	COG4172	Belongs to the ABC transporter superfamily
BE1S18E01_25040	COG4239	(ABC) transporter, permease
BE1S18E01_25050	COG4174	ABC transporter (Permease)
BE1S18E01_25060	COG4166	transmembrane transport
BE1S18E01_25070	COG0741	lytic transglycosylase activity
BE1S18E01_25070	COG1388	LysM domain
BE1S18E01_25150	COG0583	DNA-binding transcription factor activity
BE1S18E01_25160	COG1279	arginine transmembrane transporter activity
BE1S18E01_25180	COG0789	Transcriptional regulator
BE1S18E01_25200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BE1S18E01_25210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BE1S18E01_25220	COG0006	proline dipeptidase activity
BE1S18E01_25280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BE1S18E01_25310	COG3384	dioxygenase
BE1S18E01_25330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BE1S18E01_25340	COG2878	Part of a membrane complex involved in electron transport
BE1S18E01_25350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BE1S18E01_25400	COG0768	penicillin binding
BE1S18E01_25410	COG0742	ribosomal rna small subunit methyltransferase
BE1S18E01_25440	COG0830	nickel cation binding
BE1S18E01_25460	COG0804	urea catabolic process
BE1S18E01_25520	COG3015	lipoprotein NlpE involved in copper resistance
BE1S18E01_25550	COG1253	flavin adenine dinucleotide binding
BE1S18E01_25560	COG2851	Citrate transporter
BE1S18E01_25660	COG1773	rubredoxin
BE1S18E01_25670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BE1S18E01_25680	COG0596	Alpha beta hydrolase
BE1S18E01_25690	COG0583	DNA-binding transcription factor activity
BE1S18E01_25740	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BE1S18E01_25750	COG4181	ATPase activity
BE1S18E01_25840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BE1S18E01_25880	COG0306	phosphate transporter
BE1S18E01_25920	COG3958	Transketolase
BE1S18E01_25930	COG3959	Transketolase, thiamine diphosphate binding domain
BE1S18E01_25940	COG2271	Major facilitator Superfamily
BE1S18E01_25950	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_25960	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_25970	COG0583	DNA-binding transcription factor activity
BE1S18E01_26000	COG2223	nitrite transmembrane transporter activity
BE1S18E01_26010	COG2207	Transcriptional regulator
BE1S18E01_26020	COG2066	Belongs to the glutaminase family
BE1S18E01_26030	COG0242	peptide deformylase activity
BE1S18E01_26040	COG0477	Major facilitator Superfamily
BE1S18E01_26060	COG0028	Belongs to the TPP enzyme family
BE1S18E01_26090	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_26100	COG2267	carboxylic ester hydrolase activity
BE1S18E01_26120	COG2271	Major facilitator Superfamily
BE1S18E01_26150	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_26190	COG1414	Transcriptional regulator
BE1S18E01_26220	COG1024	Enoyl-CoA hydratase
BE1S18E01_26240	COG1215	transferase activity, transferring glycosyl groups
BE1S18E01_26250	COG1649	PFAM Uncharacterised BCR, COG1649
BE1S18E01_26250	COG0726	polysaccharide deacetylase
BE1S18E01_26270	COG4681	YaeQ
BE1S18E01_26290	COG0523	cobalamin synthesis protein
BE1S18E01_26310	COG1607	acyl-coa hydrolase
BE1S18E01_26330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE1S18E01_26340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BE1S18E01_26350	COG1309	transcriptional regulator
BE1S18E01_26400	COG2040	homocysteine
BE1S18E01_26410	COG0531	amino acid
BE1S18E01_26510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE1S18E01_26520	COG0477	Major facilitator Superfamily
BE1S18E01_26610	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BE1S18E01_26810	COG0739	heme binding
BE1S18E01_26810	COG1196	nuclear chromosome segregation
BE1S18E01_26810	COG0741	lytic transglycosylase activity
BE1S18E01_26830	COG1598	PFAM Uncharacterised protein family UPF0150
BE1S18E01_27440	COG0405	Gamma-glutamyltransferase
BE1S18E01_27450	COG2814	Major facilitator Superfamily
BE1S18E01_27470	COG2050	protein possibly involved in aromatic compounds catabolism
BE1S18E01_27500	COG1090	epimerase
BE1S18E01_27540	COG0420	3'-5' exonuclease activity
BE1S18E01_27590	COG0735	belongs to the Fur family
BE1S18E01_27600	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BE1S18E01_27610	COG2914	Belongs to the UPF0125 (RnfH) family
BE1S18E01_27640	COG0121	glutamine amidotransferase
BE1S18E01_27670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BE1S18E01_27690	COG0210	DNA helicase
BE1S18E01_27710	COG2885	chlorophyll binding
BE1S18E01_27720	COG0204	Acyl-transferase
BE1S18E01_27750	COG2894	cell division
BE1S18E01_27780	COG1280	lysine exporter protein (LysE YggA)
BE1S18E01_27790	COG1674	ftsk spoiiie
BE1S18E01_27800	COG0492	ferredoxin-NADP+ reductase activity
BE1S18E01_27810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BE1S18E01_27830	COG0456	acetyltransferase
BE1S18E01_27860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BE1S18E01_27870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BE1S18E01_27890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BE1S18E01_27940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BE1S18E01_27940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BE1S18E01_27970	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_27980	COG4638	Rieske (2fe-2S)
BE1S18E01_28010	COG0473	3-isopropylmalate dehydrogenase activity
BE1S18E01_28020	COG0583	DNA-binding transcription factor activity
BE1S18E01_28040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BE1S18E01_28110	COG0358	DNA primase activity
BE1S18E01_28140	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BE1S18E01_28160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BE1S18E01_28220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BE1S18E01_28240	COG0351	phosphomethylpyrimidine kinase
BE1S18E01_28240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BE1S18E01_28240	COG0352	thiamine-phosphate diphosphorylase activity
BE1S18E01_28250	COG1652	LysM domain
BE1S18E01_28300	COG1399	metal-binding, possibly nucleic acid-binding protein
BE1S18E01_28310	COG3101	peptidyl-lysine hydroxylation
BE1S18E01_28320	COG0009	L-threonylcarbamoyladenylate synthase
BE1S18E01_28330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BE1S18E01_28340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BE1S18E01_28370	COG4106	trans-aconitate 2-methyltransferase activity
BE1S18E01_28400	COG0596	Alpha beta hydrolase
BE1S18E01_28400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BE1S18E01_28400	COG2226	methyltransferase
BE1S18E01_28420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BE1S18E01_28430	COG2223	nitrite transmembrane transporter activity
BE1S18E01_28470	COG1196	nuclear chromosome segregation
BE1S18E01_28490	COG0730	response to heat
BE1S18E01_28520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BE1S18E01_28540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BE1S18E01_28650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BE1S18E01_28660	COG0489	protein tyrosine kinase activity
BE1S18E01_28680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BE1S18E01_28680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BE1S18E01_28750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BE1S18E01_28760	COG2081	HI0933 family
BE1S18E01_28780	COG0668	transmembrane transport
BE1S18E01_28820	COG0583	DNA-binding transcription factor activity
BE1S18E01_28860	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BE1S18E01_28870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BE1S18E01_28930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BE1S18E01_28980	COG2199	diguanylate cyclase activity
BE1S18E01_29000	COG2205	protein histidine kinase activity
BE1S18E01_29010	COG0745	RESPONSE REGULATOR receiver
BE1S18E01_29040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BE1S18E01_29140	COG0110	maltose O-acetyltransferase activity
BE1S18E01_29150	COG0438	transferase activity, transferring glycosyl groups
BE1S18E01_29170	COG3328	transposase activity
BE1S18E01_29310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BE1S18E01_29340	COG0583	DNA-binding transcription factor activity
BE1S18E01_29400	COG0583	DNA-binding transcription factor activity
BE1S18E01_29430	COG0583	DNA-binding transcription factor activity
BE1S18E01_29440	COG1053	succinate dehydrogenase
BE1S18E01_29470	COG1309	transcriptional regulator
BE1S18E01_29490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BE1S18E01_29500	COG2814	Major facilitator Superfamily
BE1S18E01_29510	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_29520	COG0583	DNA-binding transcription factor activity
BE1S18E01_29530	COG1063	alcohol dehydrogenase
BE1S18E01_29550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BE1S18E01_29560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BE1S18E01_29570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BE1S18E01_29610	COG2132	Multicopper oxidase
BE1S18E01_29630	COG0561	phosphatase activity
BE1S18E01_29640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BE1S18E01_29660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BE1S18E01_29690	COG1214	PFAM Peptidase M22, glycoprotease
BE1S18E01_29810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BE1S18E01_29820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BE1S18E01_29830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BE1S18E01_29900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BE1S18E01_29920	COG1846	Transcriptional regulator
BE1S18E01_29930	COG1764	response to oxidative stress
BE1S18E01_30010	COG0037	tRNA processing
BE1S18E01_30030	COG0248	Ppx GppA phosphatase
BE1S18E01_30080	COG0072	phenylalanine-tRNA ligase activity
BE1S18E01_30120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BE1S18E01_30150	COG1238	metal cluster binding
BE1S18E01_30160	COG0625	glutathione transferase activity
BE1S18E01_30190	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_30200	COG3028	Belongs to the UPF0307 family
BE1S18E01_30210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BE1S18E01_30250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BE1S18E01_30260	COG0617	tRNA 3'-terminal CCA addition
BE1S18E01_30270	COG1555	photosystem II stabilization
BE1S18E01_30280	COG3956	TIGRFAM MazG family protein
BE1S18E01_30290	COG4221	oxidoreductase activity
BE1S18E01_30300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BE1S18E01_30330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BE1S18E01_30340	COG0784	Response regulator, receiver
BE1S18E01_30340	COG2205	protein histidine kinase activity
BE1S18E01_30340	COG5002	protein histidine kinase activity
BE1S18E01_30350	COG1024	Enoyl-CoA hydratase
BE1S18E01_30360	COG2084	Dehydrogenase
BE1S18E01_30370	COG3622	Belongs to the hyi family
BE1S18E01_30440	COG0697	spore germination
BE1S18E01_30460	COG2814	Major facilitator Superfamily
BE1S18E01_30510	COG2072	flavoprotein involved in K transport
BE1S18E01_30520	COG0492	ferredoxin-NADP+ reductase activity
BE1S18E01_30530	COG0431	NADPH-dependent FMN reductase
BE1S18E01_30540	COG0798	PFAM Bile acid sodium symporter
BE1S18E01_30560	COG0640	Transcriptional regulator
BE1S18E01_30630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BE1S18E01_30680	COG2132	Multicopper oxidase
BE1S18E01_30710	COG2205	protein histidine kinase activity
BE1S18E01_30910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BE1S18E01_30930	COG0583	DNA-binding transcription factor activity
BE1S18E01_30940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BE1S18E01_30960	COG0084	hydrolase, TatD family'
BE1S18E01_30990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BE1S18E01_31030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BE1S18E01_31040	COG0440	acetolactate synthase activity
BE1S18E01_31050	COG0028	Belongs to the TPP enzyme family
BE1S18E01_31090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BE1S18E01_31100	COG0577	efflux transmembrane transporter activity
BE1S18E01_31100	COG1136	(ABC) transporter
BE1S18E01_31140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BE1S18E01_31150	COG1162	GTPase activity
BE1S18E01_31170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BE1S18E01_31210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BE1S18E01_31250	COG1426	Protein conserved in bacteria
BE1S18E01_31320	COG0793	Belongs to the peptidase S41A family
BE1S18E01_31350	COG2267	carboxylic ester hydrolase activity
BE1S18E01_31370	COG1012	belongs to the aldehyde dehydrogenase family
BE1S18E01_31380	COG3265	gluconokinase activity
BE1S18E01_31400	COG0800	Aldolase
BE1S18E01_31420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BE1S18E01_31430	COG0280	phosphate acetyltransferase
BE1S18E01_31430	COG0857	belongs to the CobB CobQ family
BE1S18E01_31440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BE1S18E01_31440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BE1S18E01_31480	COG0740	serine-type endopeptidase activity
BE1S18E01_31500	COG4774	siderophore transport
BE1S18E01_31520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BE1S18E01_31540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BE1S18E01_31540	COG2813	Specifically methylates the guanine in position
BE1S18E01_31740	COG0788	formyltetrahydrofolate deformylase activity
BE1S18E01_31790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BE1S18E01_31790	COG4651	solute:proton antiporter activity
BE1S18E01_31830	COG0724	RNA recognition motif
BE1S18E01_31840	COG0210	DNA helicase
BE1S18E01_31890	COG1733	regulation of RNA biosynthetic process
BE1S18E01_31910	COG2900	Belongs to the SlyX family
BE1S18E01_31940	COG1560	Kdo2-lipid A biosynthetic process
BE1S18E01_31960	COG1301	dicarboxylic acid transport
BE1S18E01_32070	COG0473	3-isopropylmalate dehydrogenase activity
BE1S18E01_32120	COG0583	DNA-binding transcription factor activity
BE1S18E01_32200	COG0583	DNA-binding transcription factor activity
BE1S18E01_32220	COG0625	glutathione transferase activity
BE1S18E01_32230	COG2378	regulation of single-species biofilm formation
BE1S18E01_32240	COG0546	phosphoglycolate phosphatase activity
BE1S18E01_32260	COG1530	ribonuclease E activity
BE1S18E01_32270	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_32280	COG0583	DNA-binding transcription factor activity
BE1S18E01_32290	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_32300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BE1S18E01_32320	COG0534	Mate efflux family protein
BE1S18E01_32350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BE1S18E01_32400	COG0493	'glutamate synthase
BE1S18E01_32420	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BE1S18E01_32430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BE1S18E01_32460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BE1S18E01_32480	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BE1S18E01_32480	COG0644	oxidoreductase
BE1S18E01_32510	COG4535	Mg2 and Co2 transporter CorC
BE1S18E01_32530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BE1S18E01_32570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BE1S18E01_32590	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BE1S18E01_32610	COG0484	heat shock protein binding
BE1S18E01_32620	COG0789	Transcriptional regulator
BE1S18E01_32630	COG0598	Magnesium transport protein CorA
BE1S18E01_32640	COG1185	polyribonucleotide nucleotidyltransferase activity
BE1S18E01_32670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BE1S18E01_32680	COG1074	ATP-dependent DNA helicase activity
BE1S18E01_32690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BE1S18E01_32730	COG2226	methyltransferase
BE1S18E01_32760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BE1S18E01_32780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BE1S18E01_32810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BE1S18E01_32810	COG2111	Na H antiporter
BE1S18E01_32820	COG1006	Multisubunit Na H antiporter MnhC subunit
BE1S18E01_32830	COG0651	ATP synthesis coupled electron transport
BE1S18E01_32850	COG2212	antiporter activity
BE1S18E01_32870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BE1S18E01_32890	COG0195	Participates in both transcription termination and antitermination
BE1S18E01_32960	COG0237	dephospho-CoA kinase activity
BE1S18E01_32980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BE1S18E01_33010	COG0497	DNA recombination
BE1S18E01_33030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BE1S18E01_33090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BE1S18E01_33090	COG2169	Transcriptional regulator
BE1S18E01_33100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BE1S18E01_33230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BE1S18E01_33260	COG0326	Molecular chaperone. Has ATPase activity
BE1S18E01_33290	COG2056	Na+-H+ antiporter family
BE1S18E01_33420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BE1S18E01_33440	COG0546	phosphoglycolate phosphatase activity
BE1S18E01_33450	COG1716	ATPase activity
BE1S18E01_33540	COG0181	hydroxymethylbilane synthase activity
BE1S18E01_33560	COG3275	phosphorelay sensor kinase activity
BE1S18E01_33600	COG1538	Outer membrane efflux protein
BE1S18E01_33610	COG0697	spore germination
BE1S18E01_33660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BE1S18E01_33670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BE1S18E01_33680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BE1S18E01_33690	COG0772	Belongs to the SEDS family
BE1S18E01_33740	COG4974	Belongs to the 'phage' integrase family
BE1S18E01_33750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BE1S18E01_33770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BE1S18E01_33790	COG2197	response regulator
BE1S18E01_33820	COG0793	Belongs to the peptidase S41A family
BE1S18E01_33830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BE1S18E01_33840	COG0795	lipopolysaccharide-transporting ATPase activity
BE1S18E01_33920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BE1S18E01_33920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BE1S18E01_33940	COG0004	ammonium transporteR
BE1S18E01_33950	COG0347	Belongs to the P(II) protein family
BE1S18E01_33970	COG0606	chelatase, subunit chli
BE1S18E01_33980	COG0431	NADPH-dependent FMN reductase
BE1S18E01_33990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_34000	COG0235	Class ii aldolase
BE1S18E01_34010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE1S18E01_34050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BE1S18E01_34080	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_34100	COG0477	Major facilitator Superfamily
BE1S18E01_34110	COG2860	membrane
BE1S18E01_34130	COG1253	flavin adenine dinucleotide binding
BE1S18E01_34150	COG2814	Major facilitator Superfamily
BE1S18E01_34170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BE1S18E01_34240	COG0655	NAD(P)H dehydrogenase (quinone) activity
BE1S18E01_34270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BE1S18E01_34280	COG1309	transcriptional regulator
BE1S18E01_34350	COG0758	DNA mediated transformation
BE1S18E01_34370	COG0697	spore germination
BE1S18E01_34380	COG1309	transcriptional regulator
BE1S18E01_34410	COG0386	Belongs to the glutathione peroxidase family
BE1S18E01_34440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BE1S18E01_34460	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BE1S18E01_34540	COG1121	(ABC) transporter
BE1S18E01_34550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BE1S18E01_34560	COG1280	lysine exporter protein (LysE YggA)
BE1S18E01_34570	COG2837	iron assimilation
BE1S18E01_34580	COG0281	malic enzyme
BE1S18E01_34660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BE1S18E01_34660	COG0519	Catalyzes the synthesis of GMP from XMP
BE1S18E01_34670	COG4399	Belongs to the UPF0754 family
BE1S18E01_34680	COG2259	Doxx family
BE1S18E01_34690	COG0586	Pfam SNARE associated Golgi protein
BE1S18E01_34720	COG1192	Involved in chromosome partitioning
BE1S18E01_34740	COG0271	Belongs to the BolA IbaG family
BE1S18E01_34800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BE1S18E01_34800	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BE1S18E01_34800	COG3321	synthase
BE1S18E01_34800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BE1S18E01_34810	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_34820	COG0318	PFAM AMP-dependent synthetase and ligase
BE1S18E01_34830	COG2197	response regulator
BE1S18E01_34850	COG3916	Acyl-homoserine-lactone synthase
BE1S18E01_34860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE1S18E01_34880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BE1S18E01_34890	COG1113	amino acid transport
BE1S18E01_34900	COG0697	spore germination
BE1S18E01_34910	COG0477	Major facilitator Superfamily
BE1S18E01_34920	COG1024	Enoyl-CoA hydratase
BE1S18E01_34930	COG1024	Enoyl-CoA hydratase
BE1S18E01_34940	COG1960	acyl-CoA dehydrogenase activity
BE1S18E01_34950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BE1S18E01_34990	COG1113	amino acid transport
BE1S18E01_35000	COG1113	amino acid transport
BE1S18E01_35010	COG0251	oxidation-reduction process
BE1S18E01_35090	COG0564	pseudouridine synthase activity
BE1S18E01_35210	COG2357	RelA SpoT domain protein
BE1S18E01_35230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BE1S18E01_35260	COG1802	Transcriptional regulator
BE1S18E01_35270	COG1448	Aminotransferase
BE1S18E01_35280	COG0277	FAD linked oxidase domain protein
BE1S18E01_35300	COG2186	Transcriptional regulator
BE1S18E01_35320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BE1S18E01_35350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BE1S18E01_35360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BE1S18E01_35430	COG1091	dTDP-4-dehydrorhamnose reductase activity
BE1S18E01_35500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BE1S18E01_35560	COG0728	peptidoglycan biosynthetic process
BE1S18E01_35570	COG3023	N-Acetylmuramoyl-L-alanine amidase
BE1S18E01_35680	COG0546	phosphoglycolate phosphatase activity
BE1S18E01_35690	COG1028	Short-chain dehydrogenase reductase Sdr
BE1S18E01_35720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BE1S18E01_35720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BE1S18E01_35730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BE1S18E01_35740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BE1S18E01_35750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BE1S18E01_35760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BE1S18E01_35770	COG1116	anion transmembrane transporter activity
BE1S18E01_35780	COG1309	transcriptional regulator
BE1S18E01_35790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BE1S18E01_35810	COG0196	riboflavin kinase activity
BE1S18E01_35820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BE1S18E01_35840	COG1047	Peptidyl-prolyl cis-trans
BE1S18E01_35870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BE1S18E01_35920	COG0583	DNA-binding transcription factor activity
BE1S18E01_35980	COG2951	lytic endotransglycosylase activity
BE1S18E01_35990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BE1S18E01_36020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BE1S18E01_36040	COG0671	phosphoesterase, PA-phosphatase related
BE1S18E01_36050	COG0861	Integral membrane protein TerC family
BE1S18E01_36070	COG0754	glutathionylspermidine amidase activity
BE1S18E01_36090	COG0402	S-adenosylhomocysteine deaminase activity
BE1S18E01_36130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BE1S18E01_36140	COG1230	cation diffusion facilitator family transporter
BE1S18E01_36170	COG0706	membrane insertase activity
BE1S18E01_P10030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BE1S18E01_P10260	COG1373	ATPase (AAA superfamily
BE1S18E01_P10330	COG1309	transcriptional regulator
BE1S18E01_P10380	COG0633	Ferredoxin
BE1S18E01_P10390	COG2207	Transcriptional regulator
BE1S18E01_P10490	COG0789	Transcriptional regulator
BE1S18E01_P10520	COG0582	viral genome integration into host DNA
BE1S18E01_P10550	COG2130	NADP-dependent
BE1S18E01_P10560	COG1309	transcriptional regulator
BE1S18E01_P10580	COG1902	pentaerythritol trinitrate reductase activity
BE1S18E01_P10600	COG1979	alcohol dehydrogenase
BE1S18E01_P10620	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BE1S18E01_P10670	COG0477	Major facilitator Superfamily
BE1S18E01_P10680	COG0697	spore germination
BE1S18E01_P10690	COG0604	alcohol dehydrogenase
BE1S18E01_P10690	COG3321	synthase
BE1S18E01_P10700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BE1S18E01_P10710	COG0583	DNA-binding transcription factor activity
BE1S18E01_P10720	COG4221	oxidoreductase activity
BE1S18E01_P10780	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BE1S18E01_P20030	COG0589	response to stress
BE1S18E01_P20040	COG0659	secondary active sulfate transmembrane transporter activity
BE1S18E01_P20100	COG4683	PFAM Phage derived protein Gp49-like (DUF891)