locus-tag	class	description
F2A31_00010	COG0592	DNA-directed DNA polymerase activity
F2A31_00020	COG0187	DNA topoisomerase II activity
F2A31_00025	COG0586	Pfam SNARE associated Golgi protein
F2A31_00030	COG0488	(ABC) transporter
F2A31_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F2A31_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F2A31_00100	COG3273	potassium ion transport
F2A31_00100	COG0471	metal ion transport
F2A31_00110	COG1012	belongs to the aldehyde dehydrogenase family
F2A31_00115	COG3738	Protein conserved in bacteria
F2A31_00125	COG0733	neurotransmitter:sodium symporter activity
F2A31_00165	COG2233	PERMEase
F2A31_00175	COG1309	transcriptional regulator
F2A31_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F2A31_00210	COG2814	Major facilitator Superfamily
F2A31_00215	COG0656	L-ascorbic acid biosynthetic process
F2A31_00220	COG0583	DNA-binding transcription factor activity
F2A31_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F2A31_00235	COG1064	alcohol dehydrogenase
F2A31_00240	COG2818	Glycosylase
F2A31_00255	COG1194	a g-specific adenine glycosylase
F2A31_00265	COG5487	UPF0391 membrane protein
F2A31_00270	COG2983	Belongs to the UPF0260 family
F2A31_00275	COG2133	pyrroloquinoline quinone binding
F2A31_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F2A31_00300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F2A31_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F2A31_00315	COG1335	isochorismatase
F2A31_00320	COG1522	sequence-specific DNA binding
F2A31_00330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F2A31_00340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F2A31_00345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F2A31_00350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F2A31_00370	COG0560	Phosphoserine phosphatase
F2A31_00370	COG3830	Belongs to the UPF0237 family
F2A31_00390	COG0753	catalase activity
F2A31_00415	COG0384	phenazine biosynthesis protein PhzF
F2A31_00420	COG1278	Cold shock
F2A31_00455	COG0534	Mate efflux family protein
F2A31_00460	COG0436	Aminotransferase
F2A31_00465	COG2733	membrane
F2A31_00480	COG2918	glutathione biosynthetic process
F2A31_00495	COG3150	esterase
F2A31_00510	COG0559	Belongs to the binding-protein-dependent transport system permease family
F2A31_00525	COG0410	ABC transporter
F2A31_00535	COG1247	-acetyltransferase
F2A31_00565	COG0625	glutathione transferase activity
F2A31_00570	COG1132	(ABC) transporter
F2A31_00590	COG1393	Belongs to the ArsC family
F2A31_00595	COG0708	Exodeoxyribonuclease III
F2A31_00605	COG1181	Belongs to the D-alanine--D-alanine ligase family
F2A31_00615	COG0300	oxidoreductase activity
F2A31_00630	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_00645	COG0386	Belongs to the glutathione peroxidase family
F2A31_00650	COG0189	ligase activity
F2A31_00670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F2A31_00680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F2A31_00705	COG0508	dehydrogenase complex catalyzes the overall conversion of
F2A31_00720	COG2119	membrane
F2A31_00725	COG4774	siderophore transport
F2A31_00730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F2A31_00730	COG0426	domain, Protein
F2A31_00755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F2A31_00780	COG1902	pentaerythritol trinitrate reductase activity
F2A31_00785	COG1519	Transferase
F2A31_00795	COG0668	transmembrane transport
F2A31_00800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F2A31_00830	COG3706	GGDEF domain
F2A31_00855	COG0300	oxidoreductase activity
F2A31_00865	COG0351	phosphomethylpyrimidine kinase
F2A31_00865	COG0352	thiamine-phosphate diphosphorylase activity
F2A31_00865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F2A31_00875	COG2814	Major facilitator Superfamily
F2A31_00900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F2A31_00905	COG1012	belongs to the aldehyde dehydrogenase family
F2A31_00915	COG1335	isochorismatase
F2A31_00925	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
F2A31_00940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F2A31_01005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F2A31_01030	COG0659	secondary active sulfate transmembrane transporter activity
F2A31_01050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F2A31_01085	COG0427	acetyl-CoA hydrolase
F2A31_01090	COG2205	protein histidine kinase activity
F2A31_01095	COG0745	RESPONSE REGULATOR receiver
F2A31_01135	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_01140	COG0583	DNA-binding transcription factor activity
F2A31_01160	COG4221	oxidoreductase activity
F2A31_01170	COG0488	(ABC) transporter
F2A31_01245	COG0833	amino acid
F2A31_01285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F2A31_01290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F2A31_01300	COG2226	methyltransferase
F2A31_01350	COG0070	glutamate synthase
F2A31_01350	COG0067	glutamate synthase
F2A31_01350	COG0069	glutamate synthase activity
F2A31_01355	COG0493	'glutamate synthase
F2A31_01365	COG1704	LemA family
F2A31_01370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F2A31_01395	COG3307	-O-antigen
F2A31_01405	COG2906	2 iron, 2 sulfur cluster binding
F2A31_01415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F2A31_01425	COG0194	GDP metabolic process
F2A31_01435	COG4969	Belongs to the N-Me-Phe pilin family
F2A31_01500	COG0228	four-way junction DNA binding
F2A31_01505	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F2A31_01515	COG0335	large ribosomal subunit rRNA binding
F2A31_01525	COG5380	lipid catabolic process
F2A31_01530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F2A31_01550	COG5006	permease, DMT superfamily
F2A31_01555	COG1196	nuclear chromosome segregation
F2A31_01555	COG0739	heme binding
F2A31_01555	COG0741	lytic transglycosylase activity
F2A31_01565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F2A31_01570	COG0277	FAD linked oxidase domain protein
F2A31_01595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F2A31_01600	COG2249	NAD(P)H dehydrogenase (quinone) activity
F2A31_01615	COG1289	transmembrane transporter activity
F2A31_01620	COG0628	permease
F2A31_01625	COG1192	Involved in chromosome partitioning
F2A31_01635	COG2226	methyltransferase
F2A31_01670	COG1404	Belongs to the peptidase S8 family
F2A31_01680	COG2072	flavoprotein involved in K transport
F2A31_01725	COG0471	metal ion transport
F2A31_01735	COG1983	PspC domain protein
F2A31_01745	COG1960	acyl-CoA dehydrogenase activity
F2A31_01770	COG0408	coproporphyrinogen oxidase activity
F2A31_01810	COG1127	ABC transporter
F2A31_01815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F2A31_01820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F2A31_01825	COG2854	intermembrane phospholipid transfer
F2A31_01840	COG0598	Magnesium transport protein CorA
F2A31_01855	COG1040	competence protein
F2A31_01860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F2A31_01880	COG1946	Acyl-CoA thioesterase
F2A31_01885	COG1301	dicarboxylic acid transport
F2A31_01905	COG1959	2 iron, 2 sulfur cluster binding
F2A31_01910	COG1017	nitric oxide dioxygenase activity
F2A31_01910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F2A31_01915	COG0433	COG0433 Predicted ATPase
F2A31_01935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F2A31_01955	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F2A31_02040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F2A31_02050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F2A31_02065	COG0203	ribosomal protein L17
F2A31_02085	COG1960	acyl-CoA dehydrogenase activity
F2A31_02090	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F2A31_02115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F2A31_02135	COG0339	signal peptide processing
F2A31_02140	COG0557	exoribonuclease II activity
F2A31_02215	COG0179	Fumarylacetoacetate (FAA) hydrolase
F2A31_02225	COG2207	Transcriptional regulator
F2A31_02235	COG1295	ribonuclease BN
F2A31_02265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F2A31_02290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F2A31_02290	COG2813	Specifically methylates the guanine in position
F2A31_02300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F2A31_02310	COG4771	TonB-dependent receptor
F2A31_02320	COG0740	serine-type endopeptidase activity
F2A31_02340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F2A31_02340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F2A31_02345	COG2207	Transcriptional regulator
F2A31_02345	COG1917	Cupin 2, conserved barrel domain protein
F2A31_02350	COG0697	spore germination
F2A31_02365	COG0857	belongs to the CobB CobQ family
F2A31_02365	COG0280	phosphate acetyltransferase
F2A31_02370	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F2A31_02395	COG0793	Belongs to the peptidase S41A family
F2A31_02415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F2A31_02425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F2A31_02430	COG1408	metallophosphoesterase
F2A31_02440	COG2199	diguanylate cyclase activity
F2A31_02480	COG0628	permease
F2A31_02485	COG1960	acyl-CoA dehydrogenase activity
F2A31_02505	COG1309	transcriptional regulator
F2A31_02525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F2A31_02530	COG1960	acyl-CoA dehydrogenase activity
F2A31_02585	COG2969	positive regulation of protein catabolic process
F2A31_02590	COG0625	glutathione transferase activity
F2A31_02600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F2A31_02605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F2A31_02615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F2A31_02620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F2A31_02625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F2A31_02640	COG2975	iron-sulfur cluster assembly
F2A31_02660	COG1426	Protein conserved in bacteria
F2A31_02705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F2A31_02730	COG2986	histidine ammonia-lyase
F2A31_02770	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_02775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F2A31_02790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F2A31_02800	COG1862	Preprotein translocase
F2A31_02830	COG5002	protein histidine kinase activity
F2A31_02835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F2A31_02845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F2A31_02880	COG3306	glycosyltransferase involved in LPS biosynthesis
F2A31_02905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F2A31_02945	COG0625	glutathione transferase activity
F2A31_02950	COG0583	DNA-binding transcription factor activity
F2A31_02955	COG1960	acyl-CoA dehydrogenase activity
F2A31_02960	COG1960	acyl-CoA dehydrogenase activity
F2A31_02970	COG2205	protein histidine kinase activity
F2A31_02975	COG0745	RESPONSE REGULATOR receiver
F2A31_03005	COG2096	Adenosyltransferase
F2A31_03010	COG4206	TonB-dependent receptor
F2A31_03020	COG0133	tryptophan synthase activity
F2A31_03035	COG3501	Rhs element vgr protein
F2A31_03085	COG0285	dihydrofolate synthase activity
F2A31_03100	COG0450	alkyl hydroperoxide reductase
F2A31_03120	COG0477	Major facilitator Superfamily
F2A31_03125	COG1272	protein, Hemolysin III
F2A31_03160	COG0183	Belongs to the thiolase family
F2A31_03170	COG2207	Transcriptional regulator
F2A31_03175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F2A31_03190	COG3501	Rhs element vgr protein
F2A31_03210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F2A31_03225	COG0183	Belongs to the thiolase family
F2A31_03235	COG2885	chlorophyll binding
F2A31_03235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F2A31_03240	COG2885	chlorophyll binding
F2A31_03240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F2A31_03245	COG1690	Belongs to the RtcB family
F2A31_03250	COG0833	amino acid
F2A31_03260	COG2233	PERMEase
F2A31_03275	COG1970	mechanosensitive ion channel activity
F2A31_03295	COG4772	TonB-dependent receptor
F2A31_03315	COG0354	folic acid binding
F2A31_03325	COG2824	Alkylphosphonate utilization operon protein PhnA
F2A31_03330	COG3422	double-strand break repair
F2A31_03360	COG0840	transmembrane signaling receptor activity
F2A31_03365	COG2198	Histidine kinase
F2A31_03365	COG2198	Histidine kinase
F2A31_03365	COG0643	Histidine kinase
F2A31_03365	COG0643	Histidine kinase
F2A31_03380	COG5510	response to toxic substance
F2A31_03390	COG2832	Protein of unknown function (DUF454)
F2A31_03395	COG1376	ErfK ybiS ycfS ynhG family protein
F2A31_03450	COG1289	transmembrane transporter activity
F2A31_03455	COG2814	Major facilitator Superfamily
F2A31_03470	COG0786	glutamate:sodium symporter activity
F2A31_03475	COG1115	amino acid carrier protein
F2A31_03480	COG1752	Esterase of the alpha-beta hydrolase superfamily
F2A31_03485	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F2A31_03530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F2A31_03540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F2A31_03545	COG1077	Cell shape determining protein MreB Mrl
F2A31_03550	COG1792	Involved in formation and maintenance of cell shape
F2A31_03560	COG0424	maF-like protein
F2A31_03565	COG1530	ribonuclease E activity
F2A31_03575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F2A31_03585	COG0560	Phosphoserine phosphatase
F2A31_03600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F2A31_03605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F2A31_03610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F2A31_03615	COG2205	protein histidine kinase activity
F2A31_03620	COG0745	RESPONSE REGULATOR receiver
F2A31_03630	COG0671	phosphoesterase, PA-phosphatase related
F2A31_03640	COG4771	TonB-dependent receptor
F2A31_03655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F2A31_03670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F2A31_03695	COG1113	amino acid transport
F2A31_03700	COG2828	Protein conserved in bacteria
F2A31_03705	COG0142	geranyltranstransferase activity
F2A31_03720	COG1752	Esterase of the alpha-beta hydrolase superfamily
F2A31_03740	COG2194	sulfuric ester hydrolase activity
F2A31_03745	COG0745	RESPONSE REGULATOR receiver
F2A31_03750	COG0642	Histidine kinase
F2A31_03760	COG1126	abc transporter atp-binding protein
F2A31_03765	COG0765	amino acid transport
F2A31_03770	COG0765	amino acid transport
F2A31_03780	COG0004	ammonium transporteR
F2A31_03795	COG2852	Protein conserved in bacteria
F2A31_03810	COG0525	valine-tRNA ligase activity
F2A31_03825	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_03835	COG0393	Putative heavy-metal-binding
F2A31_03840	COG0393	Putative heavy-metal-binding
F2A31_03845	COG1538	Outer membrane efflux protein
F2A31_03855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F2A31_03860	COG0671	phosphoesterase, PA-phosphatase related
F2A31_03890	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F2A31_03905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F2A31_03905	COG1648	precorrin-2 dehydrogenase activity
F2A31_03910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F2A31_03920	COG1733	regulation of RNA biosynthetic process
F2A31_03935	COG0531	amino acid
F2A31_03950	COG0321	lipoyl(octanoyl) transferase activity
F2A31_03975	COG1280	lysine exporter protein (LysE YggA)
F2A31_03985	COG0500	methyltransferase
F2A31_04005	COG2009	succinate dehydrogenase
F2A31_04010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F2A31_04015	COG1053	succinate dehydrogenase
F2A31_04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F2A31_04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F2A31_04050	COG2268	Band 7 protein
F2A31_04055	COG1585	Membrane protein implicated in regulation of membrane protease activity
F2A31_04065	COG2354	Protein conserved in bacteria
F2A31_04070	COG2321	neutral zinc metallopeptidase
F2A31_04105	COG0438	transferase activity, transferring glycosyl groups
F2A31_04145	COG0110	maltose O-acetyltransferase activity
F2A31_04160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F2A31_04165	COG0505	Belongs to the CarA family
F2A31_04190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F2A31_04205	COG2304	oxidoreductase activity
F2A31_04230	COG0584	glycerophosphoryl diester phosphodiesterase
F2A31_04235	COG2194	sulfuric ester hydrolase activity
F2A31_04240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F2A31_04245	COG2239	Acts as a magnesium transporter
F2A31_04255	COG0501	Belongs to the peptidase M48B family
F2A31_04260	COG0741	lytic transglycosylase activity
F2A31_04265	COG0037	tRNA processing
F2A31_04275	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F2A31_04280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F2A31_04290	COG1301	dicarboxylic acid transport
F2A31_04295	COG0583	DNA-binding transcription factor activity
F2A31_04410	COG0725	ABC transporter, periplasmic molybdate-binding protein
F2A31_04415	COG4149	molybdate abc transporter
F2A31_04430	COG1230	cation diffusion facilitator family transporter
F2A31_04445	COG4521	taurine ABC transporter
F2A31_04450	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F2A31_04455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F2A31_04460	COG2175	clavaminate synthase activity
F2A31_04490	COG0589	response to stress
F2A31_04505	COG0242	peptide deformylase activity
F2A31_04510	COG2852	Protein conserved in bacteria
F2A31_04535	COG0306	phosphate transporter
F2A31_04550	COG1115	amino acid carrier protein
F2A31_04560	COG0019	diaminopimelate decarboxylase activity
F2A31_04565	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F2A31_04575	COG1280	lysine exporter protein (LysE YggA)
F2A31_04580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F2A31_04600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F2A31_04630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F2A31_04650	COG1671	Belongs to the UPF0178 family
F2A31_04665	COG4591	ABC-type transport system involved in lipoprotein release permease component
F2A31_04670	COG1136	(ABC) transporter
F2A31_04675	COG2333	competence protein COMEC
F2A31_04675	COG0658	competence protein
F2A31_04685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F2A31_04685	COG0616	signal peptide processing
F2A31_04695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F2A31_04705	COG0628	permease
F2A31_04745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F2A31_04765	COG0823	Involved in the tonB-independent uptake of proteins
F2A31_04785	COG0824	Thioesterase
F2A31_04790	COG1473	amidohydrolase
F2A31_04795	COG2255	four-way junction helicase activity
F2A31_04810	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F2A31_04810	COG0047	phosphoribosylformylglycinamidine synthase activity
F2A31_04825	COG3323	Protein of unknown function (DUF1653)
F2A31_04825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F2A31_04830	COG0778	Nitroreductase
F2A31_04835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F2A31_04835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F2A31_04835	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F2A31_04845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F2A31_04845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F2A31_04850	COG1024	Enoyl-CoA hydratase
F2A31_04855	COG1056	cytidyltransferase-related domain
F2A31_04855	COG1051	belongs to the nudix hydrolase family
F2A31_04860	COG0583	DNA-binding transcription factor activity
F2A31_04865	COG1942	4-Oxalocrotonate Tautomerase
F2A31_04885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F2A31_04900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F2A31_04905	COG0602	queuosine metabolic process
F2A31_04920	COG0583	DNA-binding transcription factor activity
F2A31_04925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F2A31_04930	COG4208	sulfate ABC transporter
F2A31_04935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F2A31_04945	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F2A31_04950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F2A31_04955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F2A31_04970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F2A31_04980	COG0481	GTPase activity
F2A31_04995	COG0571	ribonuclease III activity
F2A31_05000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F2A31_05015	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F2A31_05070	COG0556	nucleotide-excision repair
F2A31_05075	COG3040	lipid binding
F2A31_05115	COG1840	ABC-type Fe3 transport system, periplasmic component
F2A31_05120	COG3842	ATPase activity
F2A31_05140	COG0583	DNA-binding transcription factor activity
F2A31_05145	COG0596	Alpha beta hydrolase
F2A31_05150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F2A31_05155	COG1773	rubredoxin
F2A31_05165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F2A31_05175	COG0175	sulfate reduction
F2A31_05190	COG0222	ribosome binding
F2A31_05195	COG1253	flavin adenine dinucleotide binding
F2A31_05210	COG3015	lipoprotein NlpE involved in copper resistance
F2A31_05225	COG0517	IMP dehydrogenase activity
F2A31_05225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F2A31_05230	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F2A31_05240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F2A31_05245	COG1137	ATPase activity
F2A31_05250	COG1538	Outer membrane efflux protein
F2A31_05290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F2A31_05305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F2A31_05320	COG0583	DNA-binding transcription factor activity
F2A31_05350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F2A31_05385	COG0204	Acyl-transferase
F2A31_05390	COG4783	chaperone-mediated protein folding
F2A31_05405	COG1610	YqeY-like protein
F2A31_05410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F2A31_05470	COG2815	serine threonine protein kinase
F2A31_05470	COG0515	serine threonine protein kinase
F2A31_05495	COG3501	Rhs element vgr protein
F2A31_05510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F2A31_05555	COG1215	transferase activity, transferring glycosyl groups
F2A31_05565	COG0726	polysaccharide deacetylase
F2A31_05565	COG1649	PFAM Uncharacterised BCR, COG1649
F2A31_05570	COG1414	Transcriptional regulator
F2A31_05575	COG2146	nitrite reductase [NAD(P)H] activity
F2A31_05590	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_05600	COG0446	pyridine nucleotide-disulphide oxidoreductase
F2A31_05605	COG2271	Major facilitator Superfamily
F2A31_05620	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_05635	COG0028	Belongs to the TPP enzyme family
F2A31_05655	COG0482	sulfurtransferase activity
F2A31_05670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F2A31_05675	COG1686	Belongs to the peptidase S11 family
F2A31_05695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F2A31_05705	COG0583	DNA-binding transcription factor activity
F2A31_05710	COG1067	ATP-dependent peptidase activity
F2A31_05730	COG0254	rRNA binding
F2A31_05750	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F2A31_05755	COG1966	Carbon starvation protein
F2A31_05760	COG2879	small protein
F2A31_05765	COG0714	Associated with various cellular activities
F2A31_05835	COG2856	Zn peptidase
F2A31_05865	COG1741	Belongs to the pirin family
F2A31_05880	COG1902	pentaerythritol trinitrate reductase activity
F2A31_05880	COG0446	pyridine nucleotide-disulphide oxidoreductase
F2A31_05895	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_05900	COG4689	acetoacetate decarboxylase
F2A31_05910	COG1902	pentaerythritol trinitrate reductase activity
F2A31_05935	COG0583	DNA-binding transcription factor activity
F2A31_05940	COG1902	pentaerythritol trinitrate reductase activity
F2A31_05970	COG3501	Rhs element vgr protein
F2A31_05975	COG3209	COG3209 Rhs family protein
F2A31_06000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F2A31_06010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F2A31_06015	COG1469	GTP cyclohydrolase I activity
F2A31_06030	COG0523	cobalamin synthesis protein
F2A31_06035	COG1414	Transcriptional regulator
F2A31_06040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F2A31_06045	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F2A31_06050	COG0183	Belongs to the thiolase family
F2A31_06055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F2A31_06060	COG0596	Alpha beta hydrolase
F2A31_06065	COG2271	Major facilitator Superfamily
F2A31_06070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F2A31_06075	COG3485	protocatechuate 3,4-dioxygenase
F2A31_06080	COG3485	protocatechuate 3,4-dioxygenase
F2A31_06085	COG0710	3-dehydroquinate dehydratase activity
F2A31_06090	COG3420	alginic acid biosynthetic process
F2A31_06095	COG3659	wide pore channel activity
F2A31_06100	COG4993	Dehydrogenase
F2A31_06110	COG2351	hydroxyisourate hydrolase activity
F2A31_06115	COG2233	PERMEase
F2A31_06125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F2A31_06130	COG2186	Transcriptional regulator
F2A31_06135	COG4266	Belongs to the allantoicase family
F2A31_06150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F2A31_06160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F2A31_06175	COG0583	DNA-binding transcription factor activity
F2A31_06185	COG2188	Transcriptional regulator
F2A31_06205	COG0010	Belongs to the arginase family
F2A31_06210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F2A31_06215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F2A31_06225	COG0243	molybdopterin cofactor binding
F2A31_06230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F2A31_06235	COG2837	iron assimilation
F2A31_06245	COG1538	Outer membrane efflux protein
F2A31_06250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F2A31_06255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F2A31_06260	COG0745	RESPONSE REGULATOR receiver
F2A31_06265	COG5002	protein histidine kinase activity
F2A31_06270	COG3040	lipid binding
F2A31_06290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F2A31_06300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F2A31_06305	COG0642	Histidine kinase
F2A31_06325	COG1309	transcriptional regulator
F2A31_06345	COG2072	flavoprotein involved in K transport
F2A31_06350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
F2A31_06355	COG1560	Kdo2-lipid A biosynthetic process
F2A31_06360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F2A31_06365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F2A31_06370	COG4770	biotin carboxylase activity
F2A31_06375	COG0501	Belongs to the peptidase M48B family
F2A31_06385	COG1765	OsmC-like protein
F2A31_06435	COG4133	protoheme IX ABC transporter activity
F2A31_06465	COG0308	aminopeptidase N
F2A31_06470	COG1760	l-serine dehydratase
F2A31_06480	COG1714	RDD family
F2A31_06490	COG0475	glutathione-regulated potassium exporter activity
F2A31_06490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F2A31_06495	COG3135	benzoate transporter
F2A31_06510	COG0583	DNA-binding transcription factor activity
F2A31_06525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F2A31_06555	COG0316	Belongs to the HesB IscA family
F2A31_06560	COG0822	iron-sulfur transferase activity
F2A31_06585	COG0776	regulation of translation
F2A31_06590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F2A31_06605	COG2137	regulation of response to DNA damage stimulus
F2A31_06615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F2A31_06620	COG1011	Hydrolase
F2A31_06625	COG1218	3'(2'),5'-bisphosphate nucleotidase
F2A31_06645	COG0268	Binds directly to 16S ribosomal RNA
F2A31_06650	COG0702	epimerase
F2A31_06655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F2A31_06700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F2A31_06705	COG0583	DNA-binding transcription factor activity
F2A31_06710	COG0424	maF-like protein
F2A31_06735	COG0778	Nitroreductase
F2A31_06765	COG1286	toxin biosynthetic process
F2A31_06810	COG3634	alkyl hydroperoxide reductase activity
F2A31_06845	COG0436	Aminotransferase
F2A31_06850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F2A31_06855	COG0386	Belongs to the glutathione peroxidase family
F2A31_06865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F2A31_06870	COG1522	sequence-specific DNA binding
F2A31_06880	COG0436	Aminotransferase
F2A31_06905	COG1253	flavin adenine dinucleotide binding
F2A31_06910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F2A31_06920	COG0012	GTP binding
F2A31_06925	COG2011	ABC-type metal ion transport system permease component
F2A31_06930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F2A31_06935	COG1464	Belongs to the NlpA lipoprotein family
F2A31_06965	COG2195	Cleaves the N-terminal amino acid of tripeptides
F2A31_06985	COG1690	Belongs to the RtcB family
F2A31_06990	COG1234	tRNA 3'-trailer cleavage
F2A31_06995	COG4650	regulator
F2A31_07035	COG2363	Small membrane protein
F2A31_07055	COG0513	Belongs to the DEAD box helicase family
F2A31_07060	COG0191	fructose-bisphosphate aldolase activity
F2A31_07065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F2A31_07075	COG3178	'Phosphotransferase
F2A31_07080	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F2A31_07090	COG1192	Involved in chromosome partitioning
F2A31_07095	COG1475	DNA binding
F2A31_07100	COG0811	peptide transport
F2A31_07110	COG1132	(ABC) transporter
F2A31_07115	COG1663	tetraacyldisaccharide 4'-kinase activity
F2A31_07140	COG0084	hydrolase, TatD family'
F2A31_07185	COG0590	tRNA wobble adenosine to inosine editing
F2A31_07205	COG0776	regulation of translation
F2A31_07220	COG2431	L-lysine efflux transmembrane transporter activity
F2A31_07235	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F2A31_07240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F2A31_07280	COG0024	Methionine aminopeptidase
F2A31_07285	COG0583	DNA-binding transcription factor activity
F2A31_07295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F2A31_07300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F2A31_07305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F2A31_07305	COG0517	IMP dehydrogenase activity
F2A31_07330	COG0552	protein localization to endoplasmic reticulum
F2A31_07355	COG4890	Cyd operon protein YbgT
F2A31_07360	COG1294	oxidase, subunit
F2A31_07385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F2A31_07405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F2A31_07410	COG0569	domain protein
F2A31_07415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F2A31_07420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F2A31_07435	COG1785	Belongs to the alkaline phosphatase family
F2A31_07455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F2A31_07460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F2A31_07465	COG0542	response to heat
F2A31_07475	COG0488	(ABC) transporter
F2A31_07480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F2A31_07485	COG2267	carboxylic ester hydrolase activity
F2A31_07495	COG1902	pentaerythritol trinitrate reductase activity
F2A31_07495	COG0446	pyridine nucleotide-disulphide oxidoreductase
F2A31_07530	COG0148	phosphopyruvate hydratase activity
F2A31_07535	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F2A31_07595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F2A31_07605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F2A31_07620	COG1802	Transcriptional regulator
F2A31_07630	COG2207	Transcriptional regulator
F2A31_07680	COG1944	ATP diphosphatase activity
F2A31_07700	COG1522	sequence-specific DNA binding
F2A31_07715	COG0439	Biotin carboxylase
F2A31_07720	COG0864	Transcriptional regulator
F2A31_07725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F2A31_07735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F2A31_07760	COG1960	acyl-CoA dehydrogenase activity
F2A31_07765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F2A31_07775	COG1024	Enoyl-CoA hydratase
F2A31_07790	COG0183	Belongs to the thiolase family
F2A31_07795	COG1250	3-hydroxyacyl-CoA dehydrogenase
F2A31_07800	COG1024	Enoyl-CoA hydratase
F2A31_07805	COG1960	acyl-CoA dehydrogenase activity
F2A31_07810	COG2814	Major facilitator Superfamily
F2A31_07815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F2A31_07820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F2A31_07830	COG2814	Major facilitator Superfamily
F2A31_07840	COG1960	acyl-CoA dehydrogenase activity
F2A31_07845	COG0235	Class ii aldolase
F2A31_07860	COG0583	DNA-binding transcription factor activity
F2A31_07875	COG1024	Enoyl-CoA hydratase
F2A31_07880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F2A31_07885	COG1960	acyl-CoA dehydrogenase activity
F2A31_07890	COG1309	transcriptional regulator
F2A31_07895	COG0318	PFAM AMP-dependent synthetase and ligase
F2A31_07910	COG2814	Major facilitator Superfamily
F2A31_07915	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_07920	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_07930	COG1960	acyl-CoA dehydrogenase activity
F2A31_07950	COG0583	DNA-binding transcription factor activity
F2A31_07960	COG4774	siderophore transport
F2A31_07990	COG2831	hemolysin activation secretion protein
F2A31_07995	COG3210	domain, Protein
F2A31_08110	COG3706	GGDEF domain
F2A31_08130	COG2205	protein histidine kinase activity
F2A31_08150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F2A31_08170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F2A31_08210	COG0537	adenosine 5'-monophosphoramidase activity
F2A31_08240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F2A31_08260	COG0730	response to heat
F2A31_08265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F2A31_08275	COG4771	TonB-dependent receptor
F2A31_08290	COG0406	alpha-ribazole phosphatase activity
F2A31_08295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F2A31_08310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F2A31_08340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F2A31_08350	COG4264	IucA IucC family
F2A31_08355	COG4264	IucA IucC family
F2A31_08360	COG2814	Major facilitator Superfamily
F2A31_08390	COG1960	acyl-CoA dehydrogenase activity
F2A31_08395	COG1960	acyl-CoA dehydrogenase activity
F2A31_08410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F2A31_08415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F2A31_08420	COG2207	Transcriptional regulator
F2A31_08425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F2A31_08435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F2A31_08460	COG0575	Belongs to the CDS family
F2A31_08465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F2A31_08470	COG0233	cytoplasmic translational termination
F2A31_08475	COG0528	UMP kinase activity
F2A31_08485	COG3852	Histidine kinase
F2A31_08495	COG1309	transcriptional regulator
F2A31_08540	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F2A31_08560	COG0697	spore germination
F2A31_08565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F2A31_08575	COG0303	'Molybdopterin
F2A31_08580	COG0521	Mo-molybdopterin cofactor biosynthetic process
F2A31_08580	COG0315	cyclic pyranopterin monophosphate synthase activity
F2A31_08600	COG0243	molybdopterin cofactor binding
F2A31_08615	COG0243	molybdopterin cofactor binding
F2A31_08620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F2A31_08625	COG2146	nitrite reductase [NAD(P)H] activity
F2A31_08625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F2A31_08630	COG2223	nitrite transmembrane transporter activity
F2A31_08640	COG1116	anion transmembrane transporter activity
F2A31_08640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F2A31_08655	COG0439	Biotin carboxylase
F2A31_08680	COG0069	glutamate synthase activity
F2A31_08700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F2A31_08705	COG1454	alcohol dehydrogenase
F2A31_08710	COG0824	Thioesterase
F2A31_08720	COG2850	peptidyl-arginine hydroxylation
F2A31_08740	COG0640	Transcriptional regulator
F2A31_08760	COG3122	Protein conserved in bacteria
F2A31_08765	COG0668	transmembrane transport
F2A31_08775	COG1132	(ABC) transporter
F2A31_08795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F2A31_08805	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F2A31_08805	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F2A31_08805	COG0506	proline dehydrogenase activity
F2A31_08810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F2A31_08815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F2A31_08825	COG3698	Phosphodiester glycosidase
F2A31_08840	COG3153	acetyltransferase
F2A31_08845	COG2353	YceI-like domain
F2A31_08870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F2A31_08875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F2A31_08890	COG3042	response to heat
F2A31_08895	COG1278	Cold shock
F2A31_08900	COG1278	Cold shock
F2A31_08920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F2A31_08920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F2A31_08945	COG3539	Fimbrial protein
F2A31_08995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F2A31_09015	COG1960	acyl-CoA dehydrogenase activity
F2A31_09020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F2A31_09040	COG3501	Rhs element vgr protein
F2A31_09045	COG3139	Protein of unknown function (DUF1315)
F2A31_09050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F2A31_09055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F2A31_09065	COG0494	nUDIX hydrolase
F2A31_09075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F2A31_09080	COG1720	tRNA m6t6A37 methyltransferase activity
F2A31_09090	COG1309	transcriptional regulator
F2A31_09115	COG0583	DNA-binding transcription factor activity
F2A31_09120	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F2A31_09125	COG0569	domain protein
F2A31_09130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F2A31_09140	COG2814	Major facilitator Superfamily
F2A31_09145	COG4607	ABC-type enterochelin transport system periplasmic component
F2A31_09150	COG4604	ABC transporter, ATP-binding protein
F2A31_09155	COG4605	iron ion homeostasis
F2A31_09160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F2A31_09170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F2A31_09200	COG0729	surface antigen
F2A31_09205	COG0477	Major facilitator Superfamily
F2A31_09225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F2A31_09235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F2A31_09270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F2A31_09330	COG1131	(ABC) transporter
F2A31_09335	COG0842	Transport permease protein
F2A31_09350	COG0772	Belongs to the SEDS family
F2A31_09355	COG2951	lytic endotransglycosylase activity
F2A31_09375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F2A31_09380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F2A31_09395	COG1643	Atp-dependent helicase
F2A31_09405	COG0450	alkyl hydroperoxide reductase
F2A31_09415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F2A31_09435	COG3634	alkyl hydroperoxide reductase activity
F2A31_09455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F2A31_09470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F2A31_09480	COG0531	amino acid
F2A31_09485	COG4303	Ethanolamine ammonia lyase large subunit
F2A31_09490	COG4302	ethanolamine ammonia-lyase activity
F2A31_09495	COG0519	Catalyzes the synthesis of GMP from XMP
F2A31_09495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F2A31_09500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F2A31_09510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F2A31_09520	COG2249	NAD(P)H dehydrogenase (quinone) activity
F2A31_09530	COG0697	spore germination
F2A31_09535	COG1923	regulation of RNA biosynthetic process
F2A31_09545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F2A31_09550	COG0802	atpase or kinase
F2A31_09580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F2A31_09585	COG3300	MHYT domain
F2A31_09585	COG5001	Diguanylate cyclase
F2A31_09605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F2A31_09610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F2A31_09615	COG1845	cytochrome c oxidase, subunit III
F2A31_09620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F2A31_09645	COG2249	NAD(P)H dehydrogenase (quinone) activity
F2A31_09650	COG1733	regulation of RNA biosynthetic process
F2A31_09655	COG0305	Participates in initiation and elongation during chromosome replication
F2A31_09660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F2A31_09675	COG1305	Transglutaminase-like
F2A31_09685	COG2308	Evidence 4 Homologs of previously reported genes of
F2A31_09695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F2A31_09715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F2A31_09725	COG0527	aspartate kinase activity
F2A31_09735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F2A31_09745	COG3038	cytochrome b561
F2A31_09750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F2A31_09755	COG2252	PERMEase
F2A31_09810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F2A31_09815	COG0138	bifunctional purine biosynthesis protein purh
F2A31_09820	COG0151	Belongs to the GarS family
F2A31_09825	COG1464	Belongs to the NlpA lipoprotein family
F2A31_09830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F2A31_09835	COG2011	ABC-type metal ion transport system permease component
F2A31_09860	COG0318	PFAM AMP-dependent synthetase and ligase
F2A31_09865	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F2A31_09870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F2A31_09875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F2A31_09905	COG0052	Belongs to the universal ribosomal protein uS2 family
F2A31_09910	COG0024	Methionine aminopeptidase
F2A31_09920	COG2223	nitrite transmembrane transporter activity
F2A31_09930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F2A31_09935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F2A31_09940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F2A31_09975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F2A31_09980	COG3161	chorismate lyase activity
F2A31_10000	COG0512	Glutamine amidotransferase of anthranilate synthase
F2A31_10010	COG3217	Mosc domain protein beta barrel domain protein
F2A31_10010	COG0633	Ferredoxin
F2A31_10030	COG0302	gtp cyclohydrolase
F2A31_10050	COG3739	integral membrane protein
F2A31_10065	COG2203	Gaf domain
F2A31_10065	COG3706	GGDEF domain
F2A31_10065	COG4251	negative regulation of phosphorylation
F2A31_10065	COG5001	Diguanylate cyclase
F2A31_10075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F2A31_10090	COG4172	Belongs to the ABC transporter superfamily
F2A31_10095	COG4239	(ABC) transporter, permease
F2A31_10100	COG4174	ABC transporter (Permease)
F2A31_10105	COG4166	transmembrane transport
F2A31_10110	COG1388	LysM domain
F2A31_10110	COG0741	lytic transglycosylase activity
F2A31_10110	COG0741	lytic transglycosylase activity
F2A31_10110	COG1388	LysM domain
F2A31_10115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F2A31_10155	COG0583	DNA-binding transcription factor activity
F2A31_10160	COG1279	arginine transmembrane transporter activity
F2A31_10180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F2A31_10185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F2A31_10190	COG0006	proline dipeptidase activity
F2A31_10220	COG2217	Heavy metal translocating P-type atpase
F2A31_10240	COG3552	Protein containing von Willebrand factor type A (VWA) domain
F2A31_10250	COG0714	Associated with various cellular activities
F2A31_10255	COG3831	ATPase activity
F2A31_10270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F2A31_10285	COG3384	dioxygenase
F2A31_10330	COG2878	Part of a membrane complex involved in electron transport
F2A31_10335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F2A31_10360	COG0768	penicillin binding
F2A31_10365	COG0742	ribosomal rna small subunit methyltransferase
F2A31_10390	COG0616	signal peptide processing
F2A31_10395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F2A31_10405	COG0573	inorganic phosphate transmembrane transporter activity
F2A31_10420	COG0076	glutamate decarboxylase activity
F2A31_10425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F2A31_10435	COG4772	TonB-dependent receptor
F2A31_10445	COG1309	transcriptional regulator
F2A31_10460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F2A31_10500	COG0564	pseudouridine synthase activity
F2A31_10515	COG0352	thiamine-phosphate diphosphorylase activity
F2A31_10570	COG0612	Peptidase, M16
F2A31_10575	COG0384	phenazine biosynthesis protein PhzF
F2A31_10595	COG2351	hydroxyisourate hydrolase activity
F2A31_10605	COG1686	Belongs to the peptidase S11 family
F2A31_10610	COG1252	NADH dehydrogenase
F2A31_10620	COG0415	Belongs to the DNA photolyase family
F2A31_10635	COG1215	transferase activity, transferring glycosyl groups
F2A31_10660	COG1271	oxidase subunit
F2A31_10665	COG1294	oxidase, subunit
F2A31_10695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F2A31_10700	COG4181	ATPase activity
F2A31_10710	COG0456	acetyltransferase
F2A31_10730	COG4771	TonB-dependent receptor
F2A31_10745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F2A31_10770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F2A31_10775	COG1597	lipid kinase activity
F2A31_10780	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
F2A31_10790	COG3210	domain, Protein
F2A31_10795	COG2831	hemolysin activation secretion protein
F2A31_10815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F2A31_10825	COG2388	GCN5-related N-acetyl-transferase
F2A31_10870	COG4681	YaeQ
F2A31_10875	COG0523	cobalamin synthesis protein
F2A31_10910	COG1024	Enoyl-CoA hydratase
F2A31_10925	COG1960	acyl-CoA dehydrogenase activity
F2A31_10950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F2A31_10955	COG1414	Transcriptional regulator
F2A31_10980	COG1012	belongs to the aldehyde dehydrogenase family
F2A31_10990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F2A31_10995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F2A31_11005	COG1960	acyl-CoA dehydrogenase activity
F2A31_11010	COG1454	alcohol dehydrogenase
F2A31_11035	COG0625	glutathione transferase activity
F2A31_11065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F2A31_11085	COG2072	flavoprotein involved in K transport
F2A31_11100	COG1252	NADH dehydrogenase
F2A31_11120	COG0251	oxidation-reduction process
F2A31_11125	COG2814	Major facilitator Superfamily
F2A31_11140	COG0183	Belongs to the thiolase family
F2A31_11145	COG1960	acyl-CoA dehydrogenase activity
F2A31_11155	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_11160	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_11180	COG0583	DNA-binding transcription factor activity
F2A31_11185	COG0318	PFAM AMP-dependent synthetase and ligase
F2A31_11190	COG1946	Acyl-CoA thioesterase
F2A31_11195	COG1960	acyl-CoA dehydrogenase activity
F2A31_11210	COG0405	Gamma-glutamyltransferase
F2A31_11215	COG2814	Major facilitator Superfamily
F2A31_11220	COG1566	PFAM secretion protein HlyD family protein
F2A31_11225	COG2050	protein possibly involved in aromatic compounds catabolism
F2A31_11235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F2A31_11240	COG1090	epimerase
F2A31_11255	COG1024	Enoyl-CoA hydratase
F2A31_11260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F2A31_11265	COG0420	3'-5' exonuclease activity
F2A31_11295	COG0735	belongs to the Fur family
F2A31_11300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F2A31_11320	COG0121	glutamine amidotransferase
F2A31_11340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F2A31_11345	COG0756	dUTP diphosphatase activity
F2A31_11350	COG0210	DNA helicase
F2A31_11355	COG2885	chlorophyll binding
F2A31_11360	COG0204	Acyl-transferase
F2A31_11375	COG2894	cell division
F2A31_11390	COG1280	lysine exporter protein (LysE YggA)
F2A31_11395	COG1674	ftsk spoiiie
F2A31_11400	COG0492	ferredoxin-NADP+ reductase activity
F2A31_11405	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F2A31_11415	COG0456	acetyltransferase
F2A31_11470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F2A31_11470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F2A31_11495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F2A31_11520	COG0564	pseudouridine synthase activity
F2A31_11530	COG0358	DNA primase activity
F2A31_11545	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F2A31_11575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F2A31_11585	COG0193	aminoacyl-tRNA hydrolase activity
F2A31_11610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F2A31_11620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F2A31_11620	COG0351	phosphomethylpyrimidine kinase
F2A31_11620	COG0352	thiamine-phosphate diphosphorylase activity
F2A31_11630	COG1652	LysM domain
F2A31_11650	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F2A31_11655	COG1399	metal-binding, possibly nucleic acid-binding protein
F2A31_11660	COG3101	peptidyl-lysine hydroxylation
F2A31_11665	COG0009	L-threonylcarbamoyladenylate synthase
F2A31_11680	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F2A31_11685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F2A31_11720	COG4166	transmembrane transport
F2A31_11770	COG4106	trans-aconitate 2-methyltransferase activity
F2A31_11790	COG2226	methyltransferase
F2A31_11790	COG0596	Alpha beta hydrolase
F2A31_11790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F2A31_11795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F2A31_11810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F2A31_11820	COG1196	nuclear chromosome segregation
F2A31_11830	COG0730	response to heat
F2A31_11845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F2A31_11920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F2A31_11925	COG0489	protein tyrosine kinase activity
F2A31_11950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F2A31_11950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F2A31_11960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F2A31_11980	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F2A31_11985	COG2081	HI0933 family
F2A31_11990	COG0668	transmembrane transport
F2A31_12010	COG0583	DNA-binding transcription factor activity
F2A31_12030	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F2A31_12035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F2A31_12040	COG0713	ATP synthesis coupled electron transport
F2A31_12050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F2A31_12065	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F2A31_12085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F2A31_12090	COG2199	diguanylate cyclase activity
F2A31_12100	COG2205	protein histidine kinase activity
F2A31_12105	COG0745	RESPONSE REGULATOR receiver
F2A31_12120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F2A31_12130	COG0732	type I restriction modification DNA specificity domain
F2A31_12155	COG1131	(ABC) transporter
F2A31_12165	COG1113	amino acid transport
F2A31_12175	COG0625	glutathione transferase activity
F2A31_12200	COG2814	Major facilitator Superfamily
F2A31_12210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F2A31_12215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F2A31_12220	COG1309	transcriptional regulator
F2A31_12240	COG1063	alcohol dehydrogenase
F2A31_12245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F2A31_12290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F2A31_12295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F2A31_12300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F2A31_12305	COG2076	Multidrug Resistance protein
F2A31_12325	COG2132	Multicopper oxidase
F2A31_12335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F2A31_12360	COG1968	undecaprenyl-diphosphatase activity
F2A31_12365	COG1214	PFAM Peptidase M22, glycoprotease
F2A31_12425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F2A31_12435	COG1595	DNA-templated transcription, initiation
F2A31_12440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F2A31_12445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F2A31_12510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F2A31_12520	COG1764	response to oxidative stress
F2A31_12545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F2A31_12545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F2A31_12560	COG0037	tRNA processing
F2A31_12570	COG0248	Ppx GppA phosphatase
F2A31_12595	COG0072	phenylalanine-tRNA ligase activity
F2A31_12620	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F2A31_12630	COG1238	metal cluster binding
F2A31_12645	COG0625	glutathione transferase activity
F2A31_12665	COG0318	PFAM AMP-dependent synthetase and ligase
F2A31_12670	COG3028	Belongs to the UPF0307 family
F2A31_12695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F2A31_12700	COG0617	tRNA 3'-terminal CCA addition
F2A31_12705	COG1555	photosystem II stabilization
F2A31_12710	COG3956	TIGRFAM MazG family protein
F2A31_12725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F2A31_12745	COG2205	protein histidine kinase activity
F2A31_12745	COG5002	protein histidine kinase activity
F2A31_12745	COG0784	Response regulator, receiver
F2A31_12750	COG1024	Enoyl-CoA hydratase
F2A31_12755	COG2084	Dehydrogenase
F2A31_12760	COG3622	Belongs to the hyi family
F2A31_12770	COG1051	belongs to the nudix hydrolase family
F2A31_12785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F2A31_12790	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F2A31_12795	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F2A31_12800	COG0789	Transcriptional regulator
F2A31_12810	COG2814	Major facilitator Superfamily
F2A31_12815	COG5285	phytanoyl-CoA dioxygenase
F2A31_12825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F2A31_12830	COG0456	acetyltransferase
F2A31_12840	COG0431	NADPH-dependent FMN reductase
F2A31_12845	COG0798	PFAM Bile acid sodium symporter
F2A31_12855	COG0640	Transcriptional regulator
F2A31_12870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F2A31_12880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F2A31_12895	COG0084	hydrolase, TatD family'
F2A31_12910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F2A31_12945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F2A31_12950	COG0440	acetolactate synthase activity
F2A31_12955	COG0028	Belongs to the TPP enzyme family
F2A31_12975	COG1466	dna polymerase III delta subunit
F2A31_12980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F2A31_12985	COG1136	(ABC) transporter
F2A31_12985	COG0577	efflux transmembrane transporter activity
F2A31_12990	COG1538	Outer membrane efflux protein
F2A31_13015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F2A31_13020	COG1162	GTPase activity
F2A31_13030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F2A31_13065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F2A31_13075	COG3781	membrane
F2A31_13110	COG1666	GTP binding
F2A31_13120	COG1956	GAF domain-containing protein
F2A31_13125	COG1607	acyl-coa hydrolase
F2A31_13140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F2A31_13140	COG3453	Protein conserved in bacteria
F2A31_13180	COG1183	phosphatidylcholine synthase activity
F2A31_13185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F2A31_13215	COG0739	heme binding
F2A31_13215	COG1196	nuclear chromosome segregation
F2A31_13215	COG0741	lytic transglycosylase activity
F2A31_13225	COG1702	phosphate starvation-inducible protein PhoH
F2A31_13240	COG4773	Receptor
F2A31_13310	COG0788	formyltetrahydrofolate deformylase activity
F2A31_13325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F2A31_13330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F2A31_13335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F2A31_13335	COG4651	solute:proton antiporter activity
F2A31_13355	COG0724	RNA recognition motif
F2A31_13360	COG0210	DNA helicase
F2A31_13385	COG1733	regulation of RNA biosynthetic process
F2A31_13390	COG0604	alcohol dehydrogenase
F2A31_13415	COG1560	Kdo2-lipid A biosynthetic process
F2A31_13490	COG0473	3-isopropylmalate dehydrogenase activity
F2A31_13525	COG0494	nUDIX hydrolase
F2A31_13535	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F2A31_13540	COG3011	Protein conserved in bacteria
F2A31_13555	COG0625	glutathione transferase activity
F2A31_13570	COG0564	pseudouridine synthase activity
F2A31_13580	COG1530	ribonuclease E activity
F2A31_13600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F2A31_13610	COG0534	Mate efflux family protein
F2A31_13615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F2A31_13650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F2A31_13675	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F2A31_13715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F2A31_13730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F2A31_13740	COG0644	oxidoreductase
F2A31_13740	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F2A31_13750	COG1595	DNA-templated transcription, initiation
F2A31_13760	COG3220	belongs to the UPF0276 family
F2A31_13775	COG0425	Belongs to the sulfur carrier protein TusA family
F2A31_13780	COG4535	Mg2 and Co2 transporter CorC
F2A31_13785	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F2A31_13805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F2A31_13815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F2A31_13825	COG0789	Transcriptional regulator
F2A31_13830	COG0598	Magnesium transport protein CorA
F2A31_13840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F2A31_13850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F2A31_13855	COG1074	ATP-dependent DNA helicase activity
F2A31_13860	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F2A31_13885	COG2226	methyltransferase
F2A31_13895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F2A31_13900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F2A31_13910	COG1116	anion transmembrane transporter activity
F2A31_13925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F2A31_13940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F2A31_13940	COG2111	Na H antiporter
F2A31_13945	COG1006	Multisubunit Na H antiporter MnhC subunit
F2A31_13950	COG0651	ATP synthesis coupled electron transport
F2A31_13960	COG2212	antiporter activity
F2A31_13970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F2A31_13980	COG0195	Participates in both transcription termination and antitermination
F2A31_14030	COG0237	dephospho-CoA kinase activity
F2A31_14045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F2A31_14055	COG0497	DNA recombination
F2A31_14065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F2A31_14095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F2A31_14155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F2A31_14170	COG0326	Molecular chaperone. Has ATPase activity
F2A31_14185	COG2056	Na+-H+ antiporter family
F2A31_14240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F2A31_14290	COG0546	phosphoglycolate phosphatase activity
F2A31_14340	COG0181	hydroxymethylbilane synthase activity
F2A31_14350	COG3275	phosphorelay sensor kinase activity
F2A31_14385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F2A31_14390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F2A31_14395	COG0772	Belongs to the SEDS family
F2A31_14420	COG4974	Belongs to the 'phage' integrase family
F2A31_14425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F2A31_14435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F2A31_14440	COG1686	Belongs to the peptidase S11 family
F2A31_14445	COG2197	response regulator
F2A31_14460	COG0793	Belongs to the peptidase S41A family
F2A31_14465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F2A31_14470	COG0795	lipopolysaccharide-transporting ATPase activity
F2A31_14475	COG0795	lipopolysaccharide-transporting ATPase activity
F2A31_14510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F2A31_14510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F2A31_14515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F2A31_14520	COG0004	ammonium transporteR
F2A31_14525	COG0347	Belongs to the P(II) protein family
F2A31_14550	COG0494	nUDIX hydrolase
F2A31_14570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F2A31_14605	COG0606	chelatase, subunit chli
F2A31_14625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F2A31_14640	COG0318	PFAM AMP-dependent synthetase and ligase
F2A31_14655	COG2860	membrane
F2A31_14665	COG1253	flavin adenine dinucleotide binding
F2A31_14680	COG2814	Major facilitator Superfamily
F2A31_14690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F2A31_14715	COG2814	Major facilitator Superfamily
F2A31_14725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F2A31_14730	COG1283	sodium-dependent phosphate transmembrane transporter activity
F2A31_14760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F2A31_14775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F2A31_14780	COG3162	membrane
F2A31_14785	COG2205	protein histidine kinase activity
F2A31_14810	COG1652	LysM domain
F2A31_14815	COG0758	DNA mediated transformation
F2A31_14830	COG1309	transcriptional regulator
F2A31_14835	COG2814	Major facilitator Superfamily
F2A31_14845	COG0386	Belongs to the glutathione peroxidase family
F2A31_14870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F2A31_14880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F2A31_14920	COG1121	(ABC) transporter
F2A31_14925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F2A31_14930	COG1280	lysine exporter protein (LysE YggA)
F2A31_14935	COG2837	iron assimilation
F2A31_14970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F2A31_14975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F2A31_14990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F2A31_14995	COG0519	Catalyzes the synthesis of GMP from XMP
F2A31_14995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F2A31_15005	COG4399	Belongs to the UPF0754 family
F2A31_15010	COG2259	Doxx family
F2A31_15015	COG0586	Pfam SNARE associated Golgi protein
F2A31_15030	COG1192	Involved in chromosome partitioning
F2A31_15040	COG0271	Belongs to the BolA IbaG family
F2A31_15060	COG0477	Major facilitator Superfamily
F2A31_15065	COG1024	Enoyl-CoA hydratase
F2A31_15070	COG1024	Enoyl-CoA hydratase
F2A31_15075	COG1960	acyl-CoA dehydrogenase activity
F2A31_15080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F2A31_15100	COG1113	amino acid transport
F2A31_15105	COG0251	oxidation-reduction process
F2A31_15120	COG1522	sequence-specific DNA binding
F2A31_15135	COG0456	acetyltransferase
F2A31_15145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F2A31_15160	COG1204	response to ionizing radiation
F2A31_15170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F2A31_15195	COG1802	Transcriptional regulator
F2A31_15205	COG0277	FAD linked oxidase domain protein
F2A31_15220	COG2186	Transcriptional regulator
F2A31_15230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F2A31_15235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F2A31_15250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F2A31_15265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F2A31_15280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F2A31_15285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F2A31_15290	COG0438	transferase activity, transferring glycosyl groups
F2A31_15340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F2A31_15345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F2A31_15385	COG3023	N-Acetylmuramoyl-L-alanine amidase
F2A31_15445	COG0546	phosphoglycolate phosphatase activity
F2A31_15450	COG1028	Short-chain dehydrogenase reductase Sdr
F2A31_15460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F2A31_15460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F2A31_15465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F2A31_15470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F2A31_15475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F2A31_15480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F2A31_15485	COG1116	anion transmembrane transporter activity
F2A31_15490	COG1309	transcriptional regulator
F2A31_15495	COG4680	protein conserved in bacteria
F2A31_15510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F2A31_15520	COG0196	riboflavin kinase activity
F2A31_15525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F2A31_15535	COG1047	Peptidyl-prolyl cis-trans
F2A31_15575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F2A31_15600	COG0583	DNA-binding transcription factor activity
F2A31_15615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F2A31_15640	COG2951	lytic endotransglycosylase activity
F2A31_15645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F2A31_15665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F2A31_15690	COG0583	DNA-binding transcription factor activity
F2A31_15695	COG0861	Integral membrane protein TerC family
F2A31_15710	COG0402	S-adenosylhomocysteine deaminase activity
F2A31_15725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F2A31_15735	COG0706	membrane insertase activity
F2A31_15750	COG0230	Belongs to the bacterial ribosomal protein bL34 family