locus-tag class description A0J50_00025 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B A0J50_00055 ENOG4105C2W permease A0J50_00065 ENOG4108IG5 Transcriptional regulator A0J50_00105 ENOG4105F27 Major Facilitator A0J50_00110 ENOG4105CV8 reductase A0J50_00115 ENOG4105HEI LysR family (Transcriptional regulator A0J50_00130 ENOG4105DQ4 alcohol dehydrogenase A0J50_00135 ENOG4108R3E Dna-3-methyladenine glycosylase i A0J50_00150 ENOG4105CEN a g-specific adenine glycosylase A0J50_00165 ENOG4108ZZ3 UPF0260 protein A0J50_00170 ENOG4105D8V Glucose sorbosone dehydrogenase A0J50_00175 ENOG4105D1H recombination factor protein RarA A0J50_00180 ENOG4105S64 Formate nitrite transporter A0J50_00200 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A0J50_00205 ENOG4108RWI nicotinamidase A0J50_00210 ENOG4105C09 Bile acid A0J50_00215 ENOG4105UQX Mate efflux family protein A0J50_00220 ENOG4105EWC Purine nucleoside phosphorylase A0J50_00235 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) A0J50_00240 ENOG4108RXX maleylacetoacetate isomerase A0J50_00250 ENOG4105C85 amino acid A0J50_00270 ENOG4105CZE histidine utilization repressor A0J50_00290 ENOG4105C85 amino acid A0J50_00300 ENOG41088SP formiminoglutamate hydrolase A0J50_00350 ENOG4108JJA ABC, transporter A0J50_00365 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 A0J50_00370 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) A0J50_00380 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) A0J50_00390 ENOG4108ZAI phosphatidylglycerophosphatase a A0J50_00395 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) A0J50_00410 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) A0J50_00445 ENOG4105KHC sulfurtransferase A0J50_00475 ENOG4105BZU Histidine kinase A0J50_00480 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A0J50_00505 ENOG4106BRA Membrane A0J50_00520 ENOG4105D9M gamma-glutamylcysteine synthetase A0J50_00530 ENOG4105CS6 Rhs element vgr protein A0J50_00555 ENOG4105IPS esterase A0J50_00560 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A0J50_00565 ENOG4108Z2U ureidoglycolate hydrolase A0J50_00575 ENOG41061H0 Monooxygenase A0J50_00590 ENOG41084YZ Hydrolase A0J50_00620 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) A0J50_00640 ENOG4105KUZ arsenate reductase A0J50_00645 ENOG4105CGK Exodeoxyribonuclease III A0J50_00665 ENOG4105D7Z glutathione synthase A0J50_00685 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) A0J50_00690 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) A0J50_00695 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) A0J50_00710 ENOG41063SB peptidase A0J50_00715 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) A0J50_00720 ENOG4107QSN dihydrolipoamide acetyltransferase A0J50_00735 ENOG4105E0K tonB-dependent siderophore receptor A0J50_00745 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) A0J50_00760 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) A0J50_00770 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) A0J50_00780 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A0J50_00825 ENOG4108UZX fmn reductase A0J50_00845 ENOG41062QD Membrane A0J50_00850 ENOG4107QN1 sodium solute A0J50_00860 ENOG4105C94 Transporter A0J50_00870 ENOG4105BZU Histidine kinase A0J50_00875 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) A0J50_00880 ENOG4108WUH Transcriptional regulator, TetR family A0J50_00895 ENOG4105RA2 Membrane A0J50_00900 ENOG4108IXY short-chain dehydrogenase reductase A0J50_00910 ENOG4105DWF phosphomethylpyrimidine kinase A0J50_00920 ENOG4107RDB Major Facilitator A0J50_00925 ENOG4108UUM single-stranded DNA-binding protein A0J50_00935 ENOG4108UMN azlc family A0J50_00945 ENOG4105C85 amino acid A0J50_00960 ENOG4105C26 Dehydrogenase A0J50_00970 ENOG4105CHJ isochorismatase hydrolase A0J50_01000 ENOG4105D94 Major Facilitator Superfamily A0J50_01005 ENOG4106NZI LysR family Transcriptional regulator A0J50_01025 ENOG4105CPC Aldo Keto reductase A0J50_01030 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) A0J50_01045 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) A0J50_01055 ENOG4105F9F transposase A0J50_01060 ENOG4105KVH Transcriptional regulator A0J50_01065 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein A0J50_01090 ENOG4105F9F transposase A0J50_01150 ENOG4105CUV Homoserine Kinase A0J50_01165 ENOG41061CK Antibiotic biosynthesis monooxygenase A0J50_01170 ENOG410631K Membrane A0J50_01185 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) A0J50_01195 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) A0J50_01225 ENOG4105CYC Transferase A0J50_01230 ENOG4105E0F Histidine kinase A0J50_01235 ENOG4105DPZ Two component transcriptional regulator (Winged helix family A0J50_01250 ENOG4105PDP Short chain dehydrogenase A0J50_01260 ENOG4105C5H ABC transporter A0J50_01340 ENOG4108IQI permease A0J50_01365 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein A0J50_01380 ENOG4105CJN penicillin-binding protein A0J50_01385 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) A0J50_01390 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) A0J50_01405 ENOG4105DHI Methyltransferase A0J50_01410 ENOG4108JQC penicillin-binding protein 1A A0J50_01435 ENOG4105E4G Type IV pilus A0J50_01455 ENOG4105CBC glutamate synthase A0J50_01470 ENOG4108V0P LemA family A0J50_01475 ENOG4105HA9 of methanol dehydrogenase type A0J50_01500 ENOG4108YSG O-Antigen polymerase A0J50_01505 ENOG4108UQY Iron-storage protein A0J50_01515 ENOG4105KME endoribonuclease L-psp A0J50_01520 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) A0J50_01530 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) A0J50_01580 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) A0J50_01590 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) A0J50_01595 ENOG4107IFA Lipase (EC 3.1.1.3) A0J50_01600 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) A0J50_01605 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) A0J50_01620 ENOG4107AQZ Membrane A0J50_01625 ENOG4107AQZ Membrane A0J50_01630 ENOG4108JQ1 Dehydrogenase A0J50_01635 ENOG4105CQB FAD linked oxidase domain protein A0J50_01645 ENOG4105VRH Antibiotic biosynthesis monooxygenase A0J50_01650 ENOG4105NF4 modulator of drug activity A0J50_01660 ENOG4107QF7 multi-drug A0J50_01665 ENOG4105EM2 membrane A0J50_01670 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A0J50_01675 ENOG4105IPI Membrane A0J50_01680 ENOG4107SKI cobyrinic Acid a,c-diamide synthase A0J50_01710 ENOG4108IQI permease A0J50_01715 ENOG4105D82 Glutamate dehydrogenase A0J50_01720 ENOG4105C8Y Acetylornithine aminotransferase A0J50_01730 ENOG4105C26 Dehydrogenase A0J50_01755 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin A0J50_01795 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit A0J50_01825 ENOG41067S9 phage shock protein C, PspC A0J50_01835 ENOG4105CSU acyl-Coa dehydrogenase A0J50_01850 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) A0J50_01865 ENOG4105ECY inositol monophosphatase A0J50_01870 ENOG4105C1J atp-dependent rna helicase A0J50_01880 ENOG4105DHJ ABC, transporter A0J50_01885 ENOG4105CY3 ABC transporter, permease A0J50_01895 ENOG4105E3I toluene tolerance A0J50_01905 ENOG4105D7N magnesium and cobalt transport protein CorA A0J50_01910 ENOG4108URH decarboxylase A0J50_01920 ENOG4105MJ2 Competence protein A0J50_01940 ENOG4105E55 glycerol-3-phosphate acyltransferase A0J50_01945 ENOG4105C29 acyl-CoA thioesterase A0J50_01950 ENOG4105CK2 sodium dicarboxylate symporter A0J50_01965 ENOG4105KPV Transcriptional regulator A0J50_01970 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) A0J50_01975 ENOG4105D7A ATP-binding protein A0J50_01980 ENOG4105C28 cystathionine A0J50_01985 ENOG41089BK Glutamine amido-transferase A0J50_01995 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) A0J50_02000 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) A0J50_02100 ENOG41067V7 50S ribosomal protein L36 A0J50_02110 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) A0J50_02135 ENOG4105C1G acyl-Coa dehydrogenase A0J50_02170 ENOG4105VKU nucleicacid-binding protein A0J50_02175 ENOG4105DGW oligopeptidase A A0J50_02180 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) A0J50_02230 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase A0J50_02240 ENOG4105CS1 NAD(P)H quinone oxidoreductase A0J50_02310 ENOG4105D6S protein involved in catabolism of external DNA A0J50_02315 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase A0J50_02360 ENOG4105C1G acyl-Coa dehydrogenase A0J50_02365 ENOG4108RZE Tetr family transcriptional regulator A0J50_02380 ENOG4107QX3 carboxylase A0J50_02385 ENOG4105C1G acyl-Coa dehydrogenase A0J50_02425 ENOG4105KB2 stringent starvation protein b A0J50_02430 ENOG4107MKT Stringent starvation protein a A0J50_02435 ENOG4108UJD 30S ribosomal protein S9 A0J50_02440 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) A0J50_02445 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) A0J50_02450 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) A0J50_02455 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) A0J50_02475 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) A0J50_02485 ENOG4107RZC phospholipase d A0J50_02500 ENOG4108KHX Diguanylate cyclase A0J50_02505 ENOG4108WS1 A0J50_02540 ENOG4107QN2 dihydrolipoyl dehydrogenase A0J50_02550 ENOG4107QPB Beta-lactamase domain protein A0J50_02575 ENOG4105NAU thioesterase Superfamily protein A0J50_02610 ENOG4105K9H YciI-like protein A0J50_02625 ENOG4105FFC UPF0187 protein A0J50_02635 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase A0J50_02640 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) A0J50_02645 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) A0J50_02650 ENOG4105VIE preprotein translocase, subunit YajC A0J50_02695 ENOG4105BZU Histidine kinase A0J50_02705 ENOG4105CM2 brancheD-chain amino acid aminotransferase A0J50_02715 ENOG4107BJW polysaccharide deacetylase A0J50_02730 ENOG4107S6X Glycosyl transferase, family 2 A0J50_02755 ENOG4105UGU tonB-dependent Receptor A0J50_02780 ENOG4108K3A Glutathione S-transferase A0J50_02785 ENOG4105EQ2 LysR family Transcriptional regulator A0J50_02795 ENOG4105CSU acyl-Coa dehydrogenase A0J50_02805 ENOG4105EB3 Histidine kinase A0J50_02810 ENOG4105E3W Two component transcriptional regulator (Winged helix family A0J50_02820 ENOG4105CNG UPF0061 protein A0J50_02840 ENOG4108WBT adenosyltransferase A0J50_02855 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) A0J50_02890 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase A0J50_02910 ENOG4105D3R alkyl hydroperoxide reductase A0J50_02925 ENOG4105CSH Transporter A0J50_02930 ENOG4108UT2 hemolysin iii A0J50_02940 ENOG41082BV acetyltransferase A0J50_02960 ENOG4105CHU acetyl-coa acetyltransferase A0J50_02965 ENOG4108R6W Transcriptional regulator, ARAC family A0J50_02975 ENOG4105TW1 Carbohydrate-selective porin OprB A0J50_02980 ENOG4105DZG Dehydrogenase A0J50_02985 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) A0J50_03005 ENOG4105CHU acetyl-coa acetyltransferase A0J50_03010 ENOG4105X0D Fimbrial protein A0J50_03015 ENOG4108WHA ompa motb domain protein A0J50_03020 ENOG4105E0Y RtcB Protein A0J50_03035 ENOG4105C2W permease A0J50_03055 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) A0J50_03065 ENOG4108VX5 3-methyladenine DNA glycosylase A0J50_03080 ENOG4108N2Y auxin Efflux A0J50_03090 ENOG4105T95 Thiol disulfide interChange protein A0J50_03095 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) A0J50_03110 ENOG4105C2W permease A0J50_03115 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) A0J50_03120 ENOG4107YYT May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity) A0J50_03125 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) A0J50_03130 ENOG4105EQP Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity) A0J50_03135 ENOG4108RDT NADH dehydrogenase NAD(P)H nitroreductase) A0J50_03140 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) A0J50_03145 ENOG4105K78 MarR family Transcriptional regulator A0J50_03150 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA A0J50_03155 ENOG4105KWI UPF0339 protein A0J50_03180 ENOG4108UNF response regulator A0J50_03185 ENOG4105M3Z response regulator A0J50_03190 ENOG4108ZGA chew protein A0J50_03195 ENOG4105C8Q Methyl-accepting chemotaxis A0J50_03200 ENOG4105CBS Chea signal transduction histidine kinase A0J50_03215 ENOG4105F9F transposase A0J50_03225 ENOG4106HKS Entericidin EcnA/B family A0J50_03235 ENOG4105WD1 Membrane A0J50_03240 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein A0J50_03280 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) A0J50_03290 ENOG4105EM2 membrane A0J50_03295 ENOG4105C2C drug resistance transporter, Bcr CflA A0J50_03310 ENOG4105BZG amino acid carrier protein A0J50_03320 ENOG4105C7B Threonine dehydratase A0J50_03365 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) A0J50_03370 ENOG4105DFF Rod shape-determining protein mreb A0J50_03380 ENOG4105VQ7 Rod shape-determining protein MreD A0J50_03385 ENOG4108Z03 MAF-like protein A0J50_03395 ENOG4105D8T Acyltransferase A0J50_03405 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein A0J50_03415 ENOG4108X0B nad(p)h dehydrogenase (quinone) A0J50_03440 ENOG4105CF7 AraC family transcriptional regulator A0J50_03465 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein A0J50_03470 ENOG4105E09 nadh pyrophosphatase A0J50_03475 ENOG4105C85 amino acid A0J50_03480 ENOG4105C7F AcnD-accessory protein PrpF A0J50_03485 ENOG4105CTB Polyprenyl synthetase A0J50_03490 ENOG4105MSB protein, conserved in bacteria A0J50_03505 ENOG4105D78 K07001 NTE family protein A0J50_03530 ENOG4105DIJ Phosphoethanolamine transferase A0J50_03535 ENOG4105XJC Two component transcriptional regulator (Winged helix family A0J50_03540 ENOG4105DHQ Histidine kinase A0J50_03555 ENOG4108M0I Transcriptional regulator A0J50_03585 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) A0J50_03605 ENOG41082CH UPF0145 protein A0J50_03610 ENOG4105K8R UPF0145 protein A0J50_03615 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A0J50_03620 ENOG4105BZS acriflavin resistance protein A0J50_03625 ENOG4105C1P efflux transporter, rnd family, mfp subunit A0J50_03630 ENOG410841Q phosphoesterase PA-phosphatase related protein A0J50_03655 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) A0J50_03675 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) A0J50_03710 ENOG4105CUB amino acid A0J50_03725 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) A0J50_03730 ENOG41084BA UPF0250 protein A0J50_03735 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A0J50_03770 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit A0J50_03775 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein A0J50_03785 ENOG4105E33 succinate dehydrogenase A0J50_03795 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 A0J50_03800 ENOG4105C7S Dehydrogenase A0J50_03805 ENOG4107QN2 dihydrolipoyl dehydrogenase A0J50_03815 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha A0J50_03825 ENOG4105CKW Inner membrane protein yedI A0J50_03835 ENOG4105EEQ Na H antiporter A0J50_03850 ENOG4105PNM synthesis protein A0J50_03870 ENOG41080TK Universal stress protein A0J50_03880 ENOG4108UQ8 endoribonuclease L-psp A0J50_03885 ENOG4108Q5F Tetr family transcriptional regulator A0J50_03895 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain A0J50_03900 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain A0J50_03915 ENOG4105HBR Rna-binding protein A0J50_03925 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) A0J50_03930 ENOG4105EEI dihydropteroate synthase A0J50_03980 ENOG4105CSH Transporter A0J50_03990 ENOG4105C6V Glycerol-3-phosphate dehydrogenase A0J50_04005 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) A0J50_04015 ENOG4105MP0 transposase A0J50_04040 ENOG41080IJ Diacylglycerol kinase A0J50_04050 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase A0J50_04070 ENOG4105E4C Lytic transglycosylase catalytic A0J50_04090 ENOG4108RRZ Transcription elongation factor GreB A0J50_04100 ENOG4105CHR reductase A0J50_04110 ENOG410642W LysR family Transcriptional regulator A0J50_04115 ENOG4105D01 (LipO)protein A0J50_04135 ENOG4108TGR phosphatase A0J50_04155 ENOG4105C1P efflux transporter, rnd family, mfp subunit A0J50_04160 ENOG4105BZS acriflavin resistance protein A0J50_04185 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit A0J50_04190 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) A0J50_04205 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) A0J50_04245 ENOG4105N14 lysine exporter protein LysE YggA A0J50_04255 ENOG4105BZJ Electron transfer flavoprotein A0J50_04310 ENOG4105D60 lipoprotein releasing system transmembrane protein A0J50_04315 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) A0J50_04330 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) A0J50_04335 ENOG4107R6F Alpha Beta Hydrolase Fold protein A0J50_04340 ENOG4108V3E phosphoribosylglycinamide formyltransferase A0J50_04350 ENOG4105C02 permease A0J50_04400 ENOG4105KCK Peptidoglycan-associated lipoprotein A0J50_04405 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) A0J50_04415 ENOG4105M8F Biopolymer transport protein exbD tolR A0J50_04420 ENOG4105E02 MotA TolQ exbB proton channel A0J50_04425 ENOG4107YD3 Thioesterase A0J50_04430 ENOG4105CH2 amidohydrolase A0J50_04450 ENOG4108ETH Formylglycinamide ribotide synthetase A0J50_04455 ENOG4105C2C drug resistance transporter, Bcr CflA A0J50_04460 ENOG4105EGD dinuclear metal center protein, YbgI family A0J50_04465 ENOG4108UKI Enoyl-CoA hydratase A0J50_04485 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen A0J50_04500 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) A0J50_04505 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) A0J50_04520 ENOG4107R11 Transcriptional regulator A0J50_04525 ENOG4108IJ6 ABC transporter A0J50_04535 ENOG4108I5D sulfate abc transporter A0J50_04545 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein A0J50_04550 ENOG4105YAZ 4-amino-4-deoxychorismate lyase A0J50_04555 ENOG4105HHA aminodeoxychorismate lyase A0J50_04570 ENOG4108IYU L-aspartate oxidase A0J50_04575 ENOG4105C0H protease A0J50_04585 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) A0J50_04590 ENOG4105C3F Signal peptidase i A0J50_04600 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) A0J50_04605 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) A0J50_04615 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) A0J50_04620 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) A0J50_04625 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase A0J50_04630 ENOG4105EMU Dehydrogenase A0J50_04665 ENOG4105BZU Histidine kinase A0J50_04675 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) A0J50_04685 ENOG4105DTR rard protein A0J50_04720 ENOG4107QS8 (LipO)protein A0J50_04725 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) A0J50_04730 ENOG4105EA8 2-Nitropropane dioxygenase A0J50_04750 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase A0J50_04785 ENOG4108YZY peptidylprolyl cis-trans isomerase A0J50_04790 ENOG4105CEP NADH dehydrogenase A0J50_04795 ENOG4105DZ1 carboxypeptidase A0J50_04805 ENOG4105E9K Isocitrate dehydrogenase A0J50_04810 ENOG4108R99 pseudouridine synthase A0J50_04830 ENOG4108ETY sodium dicarboxylate symporter A0J50_04835 ENOG4105JAB phenazine biosynthesis protein, phzf family A0J50_04880 ENOG4105D3G Pseudouridine synthase A0J50_04900 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) A0J50_04915 ENOG4108JPW Aminotransferase A0J50_04920 ENOG4105DY8 decarboxylase A0J50_04930 ENOG4105F7P transcriptional regulator AsnC family A0J50_04940 ENOG4105C85 amino acid A0J50_04945 ENOG4105CVA phosphate A0J50_04960 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) A0J50_04965 ENOG4105ERU peptidase A0J50_05005 ENOG4105DZ1 carboxypeptidase A0J50_05030 ENOG4105EJC lysr family transcriptional regulator A0J50_05035 ENOG4105DAN ATP-dependent protease A0J50_05045 ENOG4105DHU Bile acid A0J50_05065 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein A0J50_05070 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) A0J50_05075 ENOG4105D22 carbon starvation protein A0J50_05080 ENOG4105VCD cytoplasmic protein A0J50_05115 ENOG4105C2I pirin domain protein A0J50_05130 ENOG4105CEY Amp-dependent synthetase and ligase A0J50_05145 ENOG4108IPW abc transporter atp-binding protein A0J50_05175 ENOG4105WQI isochorismatase A0J50_05185 ENOG4105BZ1 (ABC) transporter A0J50_05205 ENOG4105E4F Isochorismate synthase A0J50_05220 ENOG4105NX3 Membrane A0J50_05240 ENOG4105EUJ GTP cyclohydrolase i A0J50_05260 ENOG4108DG9 Smr protein MutS2 A0J50_05285 ENOG4105DDQ anthranilate synthase A0J50_05295 ENOG4105DUX Transporter A0J50_05300 ENOG4105C5F glutamine synthetase A0J50_05310 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) A0J50_05345 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) A0J50_05350 ENOG4107QNR UPF0135 protein A0J50_05355 ENOG4105C0H protease A0J50_05365 ENOG4105C6K Malic enzyme A0J50_05370 ENOG4105BZU Histidine kinase A0J50_05375 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) A0J50_05380 ENOG4105SYT Methylenetetrahydrofolate reductase A0J50_05405 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) A0J50_05410 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) A0J50_05420 ENOG4107RNU major facilitator superfamily MFS_1 A0J50_05430 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) A0J50_05435 ENOG4105CE9 30S ribosomal protein S2 A0J50_05475 ENOG4105CVE Lytic murein transglycosylase A0J50_05480 ENOG4105CNI cell division protein FtsW A0J50_05495 ENOG4105E3A (ABC) transporter A0J50_05500 ENOG4105DA5 (ABC) transporter A0J50_05530 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A0J50_05540 ENOG4105ENT Efflux transporter rnd family, mfp subunit A0J50_05550 ENOG4105E89 ABC transporter A0J50_05555 ENOG4105DSP amino acid AbC transporter A0J50_05560 ENOG4106YG3 ABC transporter A0J50_05565 ENOG4108JEH abc transporter atp-binding protein A0J50_05575 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding A0J50_05580 ENOG4105CFP Peptidase U32 A0J50_05585 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A0J50_05590 ENOG4105JAB phenazine biosynthesis protein, phzf family A0J50_05595 ENOG4105DP0 ferredoxin-NADP reductase A0J50_05600 ENOG4108R96 Methyltransferase, YaeB family A0J50_05610 ENOG4107QHF type ii secretion system protein e A0J50_05620 ENOG4105XJC Two component transcriptional regulator (Winged helix family A0J50_05625 ENOG4105DHQ Histidine kinase A0J50_05635 ENOG4105M6F mutator MutT protein A0J50_05645 ENOG4105BZ4 penicillin-binding protein A0J50_05650 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) A0J50_05655 ENOG4105VUT cytoplasmic protein A0J50_05660 ENOG4108I0Q anthranilate phosphoribosyltransferase A0J50_05670 ENOG4105C1G acyl-Coa dehydrogenase A0J50_05680 ENOG4105CQC Prephenate dehydratase A0J50_05685 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase A0J50_05695 ENOG4105CIN aminoacyl-histidine dipeptidase A0J50_05700 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) A0J50_05725 ENOG4105M08 Membrane A0J50_05730 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) A0J50_05740 ENOG4105VEQ Cold shock protein A0J50_05745 ENOG4105C1J atp-dependent rna helicase A0J50_05755 ENOG41069NU Nitroreductase A0J50_05790 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase A0J50_05805 ENOG4105C5I Dehydrogenase A0J50_05815 ENOG4105KTH gatB Yqey A0J50_05820 ENOG4105VCC 30S ribosomal protein S21 A0J50_05845 ENOG4105D9P serine threonine protein kinase A0J50_05870 ENOG4105VEQ Cold shock protein A0J50_05895 ENOG4105D6U Sodium Glutamate Symporter A0J50_05900 ENOG4105CKD glutathione-regulated potassium-efflux system protein A0J50_05920 ENOG4105CEB Aspartate aminotransferase A0J50_05935 ENOG4105F1S paraquat-inducible protein a A0J50_05940 ENOG4105DY2 Paraquat-inducible protein b A0J50_05965 ENOG4105VT2 5-hydroxyisourate hydrolase A0J50_06020 ENOG4105DHQ Histidine kinase A0J50_06025 ENOG4105ETX regulatoR A0J50_06045 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein A0J50_06050 ENOG4105E2B Taurine dioxygenase A0J50_06060 ENOG4105F27 Major Facilitator A0J50_06075 ENOG4105HMI Membrane A0J50_06100 ENOG4105F9F transposase A0J50_06115 ENOG4105D2S major facilitator superfamily A0J50_06140 ENOG4105CK2 sodium dicarboxylate symporter A0J50_06150 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) A0J50_06155 ENOG4108UMI ABC transporter, permease A0J50_06160 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A0J50_06165 ENOG4105D01 (LipO)protein A0J50_06170 ENOG4105C12 Phosphoribosylglycinamide synthetase A0J50_06180 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) A0J50_06230 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) A0J50_06235 ENOG4105CDU Replicative dna helicase A0J50_06260 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) A0J50_06265 ENOG4105CCU oxidase (Subunit III) A0J50_06270 ENOG4105BZ9 Cytochrome C oxidase, subunit I A0J50_06275 ENOG4105E2S oxidase) subunit II A0J50_06310 ENOG4105CND Glycosyl transferase, family 2 A0J50_06315 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD A0J50_06325 ENOG4105DEN Luciferase family A0J50_06340 ENOG4105CC0 LysR family Transcriptional regulator A0J50_06355 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) A0J50_06360 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component A0J50_06365 ENOG4105GVF (ABC) transporter A0J50_06390 ENOG4105C1G acyl-Coa dehydrogenase A0J50_06395 ENOG4108MEJ flavin reductase domain protein A0J50_06400 ENOG4105D06 uba thif-type nad fad binding protein A0J50_06410 ENOG4105KRF dihydroneopterin aldolase A0J50_06420 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) A0J50_06425 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) A0J50_06435 ENOG4105C08 Histidine kinase A0J50_06445 ENOG4105CFQ glutamine synthetase A0J50_06485 ENOG4107QIJ Aconitate hydratase 2 A0J50_06495 ENOG4105EYW Ion transport protein A0J50_06500 ENOG4105F27 Major Facilitator A0J50_06515 ENOG4105DZ2 Transcriptional regulator A0J50_06540 ENOG4105I08 Pseudouridine synthase A0J50_06555 ENOG4105C34 Pseudouridine synthase A0J50_06560 ENOG4105K8N protein family UPF0079, ATPase A0J50_06565 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) A0J50_06575 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) A0J50_06580 ENOG4108TZV Membrane A0J50_06585 ENOG4108RCM Nitroreductase A0J50_06595 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) A0J50_06605 ENOG4105CX6 glutaminyL-tRNA synthetase A0J50_06610 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) A0J50_06615 ENOG4107FQ9 ethanolamine ammonia-lyase A0J50_06620 ENOG4105CPD ethanolamine ammonia-lyase A0J50_06635 ENOG4107RR1 TRANSCRIPTIONal A0J50_06645 ENOG4105C0A alcohol dehydrogenase A0J50_06650 ENOG4107QUV Domain protein A0J50_06720 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) A0J50_06735 ENOG4105GAV receptor A0J50_06740 ENOG4108ESX Receptor A0J50_06760 ENOG41089BK Glutamine amido-transferase A0J50_06795 ENOG4105KUS lysozyme A0J50_06840 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium A0J50_06845 ENOG4105C5H ABC transporter A0J50_06850 ENOG41081QV Universal stress protein A0J50_06865 ENOG4105DKK Benzoate A0J50_06870 ENOG4105EW9 transcriptional regulator AsnC family A0J50_06875 ENOG4108NIW Leucine export protein LeuE A0J50_06880 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) A0J50_06885 ENOG4105CC0 LysR family Transcriptional regulator A0J50_06895 ENOG4105CHU acetyl-coa acetyltransferase A0J50_06900 ENOG4105CHR reductase A0J50_06940 ENOG4105HSS phospholipase C A0J50_06950 ENOG4105C0A alcohol dehydrogenase A0J50_06980 ENOG4105MP0 transposase A0J50_07015 ENOG4105CBC glutamate synthase A0J50_07045 ENOG4105D8G Major Facilitator superfamily A0J50_07055 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase A0J50_07060 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein A0J50_07085 ENOG4105DUU IucA IucC family protein A0J50_07095 ENOG4105DJU Siderophore biosynthesis protein A0J50_07100 ENOG4105CIF Ornithine Cyclodeaminase A0J50_07125 ENOG4107QZF nitrite reductase NADPH large subunit A0J50_07130 ENOG4108IFG nitrite reductase, (NAD(P)H) A0J50_07165 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) A0J50_07170 ENOG4105CVM Molybdenum cofactor synthesis domain protein A0J50_07180 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A0J50_07185 ENOG4105T38 integral membrane protein A0J50_07210 ENOG4105CMR udp-glucose 4-epimerase A0J50_07275 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family A0J50_07280 ENOG4105CUX Signal transduction histidine kinase A0J50_07300 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) A0J50_07305 ENOG4105KNE Phosphatidate cytidylyltransferase A0J50_07315 ENOG4105DZP Membrane-associated zinc metalloprotease A0J50_07340 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) A0J50_07355 ENOG4105Y3E Modulates RecA activity (By similarity) A0J50_07365 ENOG4105VEJ Heat shock protein A0J50_07370 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 A0J50_07385 ENOG4105F7P transcriptional regulator AsnC family A0J50_07395 ENOG4105C85 amino acid A0J50_07415 ENOG4105CHH sulfate transporter A0J50_07425 ENOG4105D8V Glucose sorbosone dehydrogenase A0J50_07435 ENOG4105BZU Histidine kinase A0J50_07455 ENOG4105DE4 1-phosphofructokinase A0J50_07460 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) A0J50_07480 ENOG4108ZJF Glcg protein A0J50_07485 ENOG4105CWM branched-chain amino acid transport system II carrier protein A0J50_07490 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) A0J50_07495 ENOG4105CC0 LysR family Transcriptional regulator A0J50_07505 ENOG4105M2J Glutaredoxin A0J50_07510 ENOG4105C8Y Acetylornithine aminotransferase A0J50_07515 ENOG4105C2X Arabinose 5-phosphate isomerase A0J50_07540 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) A0J50_07550 ENOG41068P6 UPF0319 protein A0J50_07570 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii A0J50_07575 ENOG4105C4M (Ubiquinol oxidase) subunit I A0J50_07585 ENOG4105PV3 Inner membrane protein yqiJ A0J50_07605 ENOG4105HDD phospholipase A0J50_07610 ENOG4105CZN Potassium uptake protein A0J50_07620 ENOG4105C7B Threonine dehydratase A0J50_07650 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) A0J50_07655 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit A0J50_07665 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) A0J50_07680 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A0J50_07720 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) A0J50_07725 ENOG4107VMU Membrane A0J50_07740 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) A0J50_07750 ENOG4107QP7 CoA-transferase subunit A A0J50_07755 ENOG4107QNJ CoA-transferase subunit B A0J50_07760 ENOG4105CHU acetyl-coa acetyltransferase A0J50_07770 ENOG4105F2Z 3-oxoadipate enol-lactonase A0J50_07775 ENOG4105D2S major facilitator superfamily A0J50_07780 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase A0J50_07785 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta A0J50_07790 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha A0J50_07795 ENOG4105FF2 Type I DHQase A0J50_07800 ENOG4106JPM 3-dehydroshikimate dehydratase A0J50_07805 ENOG4105TW1 Carbohydrate-selective porin OprB A0J50_07810 ENOG4105DZG Dehydrogenase A0J50_07835 ENOG4107HP6 Transcriptional regulator A0J50_07840 ENOG4108PTX LysR family Transcriptional regulator A0J50_07870 ENOG4105DNH Major Facilitator A0J50_07880 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) A0J50_07900 ENOG4105FUY alpha subunit A0J50_07910 ENOG4105CHR reductase A0J50_07930 ENOG4105F11 amine oxidase A0J50_07940 ENOG4105C26 Dehydrogenase A0J50_07945 ENOG4105F2Z 3-oxoadipate enol-lactonase A0J50_07950 ENOG4105CHU acetyl-coa acetyltransferase A0J50_07955 ENOG4107QNJ CoA-transferase subunit B A0J50_07960 ENOG4107QP7 CoA-transferase subunit A A0J50_07970 ENOG4105NN7 muconolactone delta-isomerase A0J50_07975 ENOG4105DTQ mandelate racemase muconate lactonizing A0J50_07980 ENOG4108KB2 LysR family Transcriptional regulator A0J50_07990 ENOG4107EJG GntR family transcriptional regulator A0J50_08010 ENOG4105CZJ Aldehyde dehydrogenase A0J50_08015 ENOG4105VT2 5-hydroxyisourate hydrolase A0J50_08020 ENOG4105C2W permease A0J50_08030 ENOG41061H0 Monooxygenase A0J50_08035 ENOG41073TP transcriptional regulator A0J50_08050 ENOG4107XKF NMT1 THI5 Like Domain Protein A0J50_08060 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component A0J50_08080 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A0J50_08120 ENOG4107Z3H Transcriptional regulator, TetR family A0J50_08130 ENOG41061TZ Short-chain dehydrogenase reductase Sdr A0J50_08140 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr A0J50_08160 ENOG4105CEY Amp-dependent synthetase and ligase A0J50_08180 ENOG4105F9F transposase A0J50_08190 ENOG4106KR7 LysR family Transcriptional regulator A0J50_08215 ENOG4108JQ1 Dehydrogenase A0J50_08220 ENOG4105JSC dimethylmenaquinone methyltransferase A0J50_08235 ENOG4105EVZ LysR family transcriptional regulator A0J50_08240 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) A0J50_08245 ENOG4105C26 Dehydrogenase A0J50_08270 ENOG4105CZJ Aldehyde dehydrogenase A0J50_08275 ENOG4105C01 Dihydroxy-acid dehydratase A0J50_08285 ENOG4105DDW LysR family Transcriptional regulator A0J50_08290 ENOG4105EXW epimerase dehydratase A0J50_08300 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A0J50_08315 ENOG4105EHG Permease protein A0J50_08320 ENOG4105E0A ABC, transporter A0J50_08340 ENOG4105C5T Phosphoribosyl pyrophosphate synthase A0J50_08430 ENOG4105M03 Domain of unknown function (DUF955) A0J50_08465 ENOG4108R6W Transcriptional regulator, ARAC family A0J50_08470 ENOG4108821 RND type efflux pump A0J50_08540 ENOG4108JJB ABC transporter A0J50_08560 ENOG4105MP0 transposase A0J50_08570 ENOG41088T4 Helicase IV A0J50_08580 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) A0J50_08660 ENOG4105X0I Fimbrial A0J50_08715 ENOG4107RZC phospholipase d A0J50_08725 ENOG4105JJR Histidine kinase A0J50_08730 ENOG4105CK6 Two component transcriptional regulator (Winged helix family A0J50_08735 ENOG4105C1P efflux transporter, rnd family, mfp subunit A0J50_08750 ENOG4108IGT Dipeptidase A0J50_08755 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E A0J50_08765 ENOG41086XE Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity) A0J50_08770 ENOG4105JIE May be involved in the transport of PQQ or its precursor to the periplasm (By similarity) A0J50_08775 ENOG4107T31 5'-nucleotidase A0J50_08785 ENOG4105WQI isochorismatase A0J50_08790 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase A0J50_08795 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) A0J50_08800 ENOG4105E0C molybdate abc transporter A0J50_08805 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein A0J50_08810 ENOG4105F4R Transcriptional regulator mode A0J50_08815 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit A0J50_08820 ENOG4108YS2 small subunit A0J50_08825 ENOG4105F57 Anthranilate dioxygenase reductase A0J50_08850 ENOG4105CHR reductase A0J50_08860 ENOG4105D2S major facilitator superfamily A0J50_08865 ENOG4105CF7 AraC family transcriptional regulator A0J50_08905 ENOG4108M0I Transcriptional regulator A0J50_08920 ENOG4105CRW Short chain fatty acid transporter A0J50_08925 ENOG4105CHU acetyl-coa acetyltransferase A0J50_08935 ENOG4107YNJ LysR family Transcriptional regulator A0J50_08950 ENOG4108IJ0 Aspartate ammonia-lyase A0J50_08960 ENOG4105CSH Transporter A0J50_08970 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) A0J50_08975 ENOG4105KVH Transcriptional regulator A0J50_08980 ENOG4105UEI Transcriptional Regulator AraC Family A0J50_08995 ENOG4108VCT Sulfite exporter TauE/SafE A0J50_09015 ENOG4105FFC UPF0187 protein A0J50_09025 ENOG4105CHR reductase A0J50_09040 ENOG4105CPP Dehydrogenase, E1 component A0J50_09045 ENOG4107R0V Pyruvate dehydrogenase A0J50_09050 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) A0J50_09065 ENOG4105BZU Histidine kinase A0J50_09080 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) A0J50_09085 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) A0J50_09125 ENOG4107U5X Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) A0J50_09135 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) A0J50_09150 ENOG4105C28 cystathionine A0J50_09170 ENOG4105K59 histidine triad (HIT) protein A0J50_09195 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) A0J50_09200 ENOG4105CNM Receptor A0J50_09220 ENOG4107TSN permease A0J50_09225 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) A0J50_09245 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) A0J50_09250 ENOG4108YZT Adenosylcobinamide kinase A0J50_09260 ENOG4107VXZ Hydrolase A0J50_09270 ENOG4108Z66 YbaK ebsC protein A0J50_09285 ENOG4105C1G acyl-Coa dehydrogenase A0J50_09290 ENOG4105C1G acyl-Coa dehydrogenase A0J50_09295 ENOG4105EEF Alkane 1-monooxygenase A0J50_09300 ENOG4105E7U AraC family transcriptional regulator A0J50_09305 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) A0J50_09310 ENOG4105K70 DNA-binding protein A0J50_09325 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family A0J50_09335 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins A0J50_09340 ENOG4108Z4V iron-sulfur cluster assembly A0J50_09355 ENOG4108ZIT Ferredoxin, 2FE-2S A0J50_09360 ENOG4105F8J Adenylate Guanylate cyclase A0J50_09370 ENOG4108JA2 transcriptioN-repair coupling factor A0J50_09390 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) A0J50_09395 ENOG4105K4T epimerase A0J50_09445 ENOG4107QSI ABC, transporter A0J50_09475 ENOG4105SG9 biopolymer transport protein, ExbD A0J50_09485 ENOG4107QP3 malate synthase g A0J50_09490 ENOG4105D6Z AFG1 family ATPase A0J50_09500 ENOG4107RN6 Monooxygenase A0J50_09505 ENOG4105DWU Membrane A0J50_09520 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) A0J50_09525 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) A0J50_09540 ENOG4108Z6B deaminase A0J50_09560 ENOG4108RTD type II secretion system protein K A0J50_09585 ENOG4105F8V Hydrolase, tatD family A0J50_09595 ENOG4107QRG dna polymerase iii A0J50_09605 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) A0J50_09625 ENOG4105FA0 parb-like partition protein A0J50_09630 ENOG4107QJE Chromosome Partitioning Protein A0J50_09640 ENOG4108S0S Nucleotidyl transferase A0J50_09645 ENOG4105EHM Aminoglycoside phosphotransferase A0J50_09650 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) A0J50_09655 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) A0J50_09660 ENOG4105D2N Aldolase A0J50_09680 ENOG4108UHJ MAF-like protein A0J50_09685 ENOG4105EZE Cupin 4 family protein A0J50_09695 ENOG41080HT Transcriptional regulator, arsr family A0J50_09705 ENOG4105XPP Protein of unknown function (DUF1275) A0J50_09710 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme A0J50_09715 ENOG4105BZ1 (ABC) transporter A0J50_09725 ENOG4108ZX5 transcriptional regulator A0J50_09735 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) A0J50_09740 ENOG4105CK7 Sodium proline symporter A0J50_09745 ENOG4105EW9 transcriptional regulator AsnC family A0J50_09750 ENOG4105C26 Dehydrogenase A0J50_09755 ENOG4105YGK Pfam:UPF0157 A0J50_09770 ENOG4108T58 Mg2 transport protein CorA A0J50_09780 ENOG4108YYC ycei family A0J50_09790 ENOG4105CV1 Transketolase (EC 2.2.1.1) A0J50_09815 ENOG4108HWY Beta-lactamase A0J50_09860 ENOG4105X0I Fimbrial A0J50_09900 ENOG4108IPJ Membrane A0J50_09910 ENOG4105ETS cytosine purines uracil thiamine allantoin A0J50_09920 ENOG4105HEI LysR family (Transcriptional regulator A0J50_09935 ENOG41067SE Tetr family transcriptional regulator A0J50_09950 ENOG4105EW9 transcriptional regulator AsnC family A0J50_09960 ENOG4105CDA abc transporter atp-binding protein A0J50_09965 ENOG4105DRP amino acid AbC transporter A0J50_09970 ENOG4105EAD ABC transporter A0J50_09990 ENOG4107T8P acyl-Coa dehydrogenase A0J50_10005 ENOG4105D01 (LipO)protein A0J50_10010 ENOG4105D01 (LipO)protein A0J50_10015 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) A0J50_10020 ENOG4108UMI ABC transporter, permease A0J50_10025 ENOG4105C3G gtp-binding protein A0J50_10050 ENOG4108UMN azlc family A0J50_10055 ENOG4105ZED uncharacterized protein ygaH A0J50_10085 ENOG4106AXJ AraC family transcriptional regulator A0J50_10090 ENOG4108V06 Glutathione peroxidase A0J50_10100 ENOG4105CHM Aminotransferase A0J50_10105 ENOG4105CK2 sodium dicarboxylate symporter A0J50_10120 ENOG4105C0B DNA polymerase III (alpha subunit) A0J50_10145 ENOG4108JU3 Alkyl hydroperoxide reductase A0J50_10160 ENOG4108KB2 LysR family Transcriptional regulator A0J50_10165 ENOG4105CAU Arsenical resistance protein, ArsH A0J50_10170 ENOG4105D6J arsenicaL-resistance protein A0J50_10200 ENOG4105CBN LysR family transcriptional regulator A0J50_10210 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease A0J50_10220 ENOG4105E2B Taurine dioxygenase A0J50_10225 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component A0J50_10230 ENOG4108IY8 ABC, transporter A0J50_10265 ENOG4105C4M (Ubiquinol oxidase) subunit I A0J50_10270 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii A0J50_10275 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A0J50_10280 ENOG4108K70 Transcriptional regulator A0J50_10315 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) A0J50_10320 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase A0J50_10330 ENOG4105ETT transcriptional Regulator, LysR family A0J50_10335 ENOG4107EXU Short-chain dehydrogenase reductase Sdr A0J50_10350 ENOG4105DXI Major Facilitator superfamily A0J50_10355 ENOG4105E1F short-chain dehydrogenase reductase A0J50_10375 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A0J50_10380 ENOG4105F9F transposase A0J50_10390 ENOG41067MG lrgb family A0J50_10395 ENOG4105VAW lrga family A0J50_10400 ENOG4105CMU LysR family (Transcriptional regulator A0J50_10410 ENOG4105CYM Glutathione S-transferase A0J50_10430 ENOG4105CBN LysR family transcriptional regulator A0J50_10435 ENOG4105CHR reductase A0J50_10445 ENOG4105D7W serine acetyltransferase A0J50_10450 ENOG4105ESN nucleotide-binding protein A0J50_10455 ENOG4105C9B Cysteine desulfurase A0J50_10465 ENOG4105EXG Transcriptional regulator A0J50_10470 ENOG4105CT1 (ABC) transporter A0J50_10475 ENOG4107RP9 extracellular solute-binding protein, family 3 A0J50_10485 ENOG4108HW4 amino acid AbC transporter A0J50_10490 ENOG4105EAD ABC transporter A0J50_10500 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase A0J50_10505 ENOG4105BZU Histidine kinase A0J50_10515 ENOG4105EW9 transcriptional regulator AsnC family A0J50_10525 ENOG4105KT5 UmuD protein A0J50_10540 ENOG4105F9F transposase A0J50_10550 ENOG4105CYX Short-chain dehydrogenase reductase Sdr A0J50_10600 ENOG4105HEI LysR family (Transcriptional regulator A0J50_10610 ENOG4105D2S major facilitator superfamily A0J50_10625 ENOG4105CEY Amp-dependent synthetase and ligase A0J50_10630 ENOG4105R8C Transcriptional regulator A0J50_10635 ENOG4105C1G acyl-Coa dehydrogenase A0J50_10640 ENOG4107QX3 carboxylase A0J50_10645 ENOG4105E39 Enoyl-CoA hydratase A0J50_10700 ENOG4107QP7 CoA-transferase subunit A A0J50_10705 ENOG4107RGD Major Facilitator superfamily A0J50_10710 ENOG4105C1G acyl-Coa dehydrogenase A0J50_10720 ENOG4108R85 Short chain dehydrogenase A0J50_10730 ENOG4105CHU acetyl-coa acetyltransferase A0J50_10740 ENOG4105EQ0 Major Facilitator superfamily A0J50_10745 ENOG4105EA8 2-Nitropropane dioxygenase A0J50_10750 ENOG4108UKI Enoyl-CoA hydratase A0J50_10770 ENOG4107RGD Major Facilitator superfamily A0J50_10775 ENOG4108KAZ Involved in phosphonate degradation (By similarity) A0J50_10790 ENOG4107RCV ABC transporter, permease A0J50_10795 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) A0J50_10800 ENOG4105C4Y ABC transporter A0J50_10815 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase A0J50_10820 ENOG4107HP6 Transcriptional regulator A0J50_10830 ENOG4105HEI LysR family (Transcriptional regulator A0J50_10855 ENOG4107YAU phenylacetic acid degradation protein A0J50_10865 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein A0J50_10870 ENOG4105DZS Phenylacetate-CoA ligase A0J50_10875 ENOG4105CHU acetyl-coa acetyltransferase A0J50_10880 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase A0J50_10885 ENOG4108UKI Enoyl-CoA hydratase A0J50_10890 ENOG4105E39 Enoyl-CoA hydratase A0J50_10895 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) A0J50_10900 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit A0J50_10905 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit A0J50_10910 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit A0J50_10915 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit A0J50_10920 ENOG4105DXM phenylacetic acid degradation protein A0J50_10925 ENOG4105EJQ L-serine dehydratase A0J50_10940 ENOG4108Z4X TRANSCRIPTIONal A0J50_10950 ENOG4105WPN DNA integration recombination invertion protein A0J50_10955 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A0J50_10970 ENOG4105DJ2 Major Facilitator Superfamily A0J50_10975 ENOG4107Y2X deaminase A0J50_10985 ENOG4105EMY transcriptional regulator A0J50_10995 ENOG4105E2A Dehydrogenase A0J50_11000 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) A0J50_11035 ENOG4105D5K Hemolysin activator protein A0J50_11040 ENOG4107R4J Chloride channel A0J50_11045 ENOG4108JIK carboxylase A0J50_11065 ENOG4105C5A transporter A0J50_11070 ENOG4108WAV Transcriptional regulator A0J50_11080 ENOG4108WQI RNA Polymerase A0J50_11090 ENOG4105E18 UPF0276 protein A0J50_11145 ENOG4105ECR NmrA family A0J50_11150 ENOG4105KVH Transcriptional regulator A0J50_11170 ENOG4105BZU Histidine kinase A0J50_11180 ENOG4108S3W Anti-feci sigma factor, fecr A0J50_11210 ENOG4105D2S major facilitator superfamily A0J50_11215 ENOG4105CPW cytochrome b561 A0J50_11220 ENOG4107VGR Catalase A0J50_11225 ENOG4105KVH Transcriptional regulator A0J50_11240 ENOG4105DZA Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity) A0J50_11250 ENOG4105CD3 dihydroorotase A0J50_11270 ENOG4105D5Q Arginine ornithine antiporter A0J50_11275 ENOG4105CRN Aminoglycoside phosphotransferase A0J50_11285 ENOG4108ZX5 transcriptional regulator A0J50_11305 ENOG4108Z4U Ferredoxin A0J50_11315 ENOG4107ZBN O-methyltransferase A0J50_11325 ENOG4105EQK -acetyltransferase A0J50_11335 ENOG4105C42 Type I secretion membrane fusion protein (HlyD A0J50_11345 ENOG4105DFG type I secretion outer membrane protein A0J50_11350 ENOG4108IUZ ABC transporter A0J50_11355 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA A0J50_11365 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase A0J50_11370 ENOG4105C2X Arabinose 5-phosphate isomerase A0J50_11405 ENOG4107YPT transcriptional regulator A0J50_11420 ENOG4105CUY Mechanosensitive ion channel A0J50_11460 ENOG4105R8C Transcriptional regulator A0J50_11485 ENOG4105F2W methyltransferase A0J50_11490 ENOG4105EW9 transcriptional regulator AsnC family A0J50_11495 ENOG4105II7 pyrroline-5-carboxylate reductase A0J50_11505 ENOG410829K Lysine exporter protein (Lyse ygga) A0J50_11540 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) A0J50_11600 ENOG4105EUV Phenol 2-monooxygenase A0J50_11620 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein A0J50_11630 ENOG4108KB2 LysR family Transcriptional regulator A0J50_11635 ENOG4105FUY alpha subunit A0J50_11640 ENOG4108UKV benzoate 1,2-dioxygenase A0J50_11645 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein A0J50_11650 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase A0J50_11655 ENOG4105DKK Benzoate A0J50_11660 ENOG4105D2S major facilitator superfamily A0J50_11680 ENOG4105D3R alkyl hydroperoxide reductase A0J50_11700 ENOG4108JU3 Alkyl hydroperoxide reductase A0J50_11710 ENOG4108K3A Glutathione S-transferase A0J50_11720 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) A0J50_11730 ENOG4108TGY Glutathione S-transferase A0J50_11740 ENOG4108ZG0 Ompa motb domain protein A0J50_11745 ENOG4105CD3 dihydroorotase A0J50_11775 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit A0J50_11790 ENOG4108UKZ OsmC family A0J50_11795 ENOG4107RYR Transcriptional regulator, Crp Fnr family A0J50_11800 ENOG4105CPC Aldo Keto reductase A0J50_11825 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase A0J50_11835 ENOG4105CFH Aspartokinase A0J50_11845 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) A0J50_11855 ENOG4105CPW cytochrome b561 A0J50_11865 ENOG4105C7N Xanthine uracil vitamin C permease A0J50_11895 ENOG4105F95 Monooxygenase A0J50_11900 ENOG4105JQZ Methyltransferase A0J50_11910 ENOG4107RN6 Monooxygenase A0J50_11930 ENOG4105DDY UPF0142 protein ycaO A0J50_11935 ENOG4105EPF Outer membrane porin A0J50_11940 ENOG4105D2S major facilitator superfamily A0J50_11945 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) A0J50_11950 ENOG4105E6M Sulphatase-modifying factor protein A0J50_11965 ENOG4105E3J oxidoreductase A0J50_11980 ENOG4108SC4 )-transporter A0J50_11995 ENOG4105C85 amino acid A0J50_12035 ENOG4105CUB amino acid A0J50_12055 ENOG4107Y60 (LipO)protein A0J50_12065 ENOG4106B0W Curli production assembly transport component CsgG A0J50_12085 ENOG4108M3P Membrane A0J50_12125 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) A0J50_12150 ENOG4108JQ5 ABC transporter A0J50_12155 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component A0J50_12160 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component A0J50_12165 ENOG4105E43 Extracellular solute-binding protein, family 5 A0J50_12170 ENOG4105E9H Lytic Murein transglycosylase A0J50_12175 ENOG4108JDX DNA polymerase iii, epsilon subunit A0J50_12185 ENOG4105E09 nadh pyrophosphatase A0J50_12195 ENOG4105W4M Transport-associated protein A0J50_12205 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) A0J50_12215 ENOG4108ZUB Lysine exporter protein (Lyse ygga) A0J50_12225 ENOG4105W1Y Transcriptional regulator A0J50_12235 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family A0J50_12240 ENOG4105D0A hydroxylase A0J50_12245 ENOG4107RAQ aminopeptidase A0J50_12295 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b A0J50_12305 ENOG4105D82 Glutamate dehydrogenase A0J50_12310 ENOG4108R3D Electron transport complex A0J50_12315 ENOG4105CSM endonuclease III A0J50_12335 ENOG4105CJN penicillin-binding protein A0J50_12340 ENOG4106H78 methyltransferase A0J50_12355 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) A0J50_12365 ENOG4105CQM Urea amidohydrolase subunit alpha A0J50_12395 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion A0J50_12400 ENOG4107RET Isocitrate lyase A0J50_12410 ENOG4105C37 (CBS) domain A0J50_12415 ENOG4105D4T Citrate transporter A0J50_12430 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) A0J50_12440 ENOG4108MRJ A0J50_12460 ENOG4105VCQ rubredoxin A0J50_12465 ENOG4107QZF nitrite reductase NADPH large subunit A0J50_12470 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) A0J50_12475 ENOG4105C5Q Transcriptional regulator A0J50_12495 ENOG4107U91 Rhomboid family A0J50_12505 ENOG4108I0Y (ABC) transporter A0J50_12510 ENOG4108UJV acyl-CoA thioesterase i A0J50_12530 ENOG4107RNH Outer membrane receptor FepA A0J50_12545 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) A0J50_12550 ENOG4105E6M Sulphatase-modifying factor protein A0J50_12565 ENOG4105CJ3 phosphate transporter A0J50_12605 ENOG4105CSP Major Facilitator Superfamily A0J50_12615 ENOG4108PZW LysR family Transcriptional regulator A0J50_12625 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) A0J50_12630 ENOG4105EU0 Major facilitator Superfamily A0J50_12635 ENOG4108R6W Transcriptional regulator, ARAC family A0J50_12640 ENOG4105CSV Glutaminase A0J50_12645 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) A0J50_12650 ENOG4105CSH Transporter A0J50_12660 ENOG4105C7K acetolactate synthase A0J50_12675 ENOG4105CHR reductase A0J50_12680 ENOG4108MXF Alpha Beta Hydrolase A0J50_12690 ENOG4105DJB Major Facilitator Superfamily A0J50_12705 ENOG4105CHR reductase A0J50_12725 ENOG41069M3 Transcriptional regulator A0J50_12740 ENOG4105E9F Enoyl-CoA hydratase A0J50_12750 ENOG4105CND Glycosyl transferase, family 2 A0J50_12755 ENOG4107BJW polysaccharide deacetylase A0J50_12765 ENOG4108VWS Yaeq family A0J50_12885 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) A0J50_12890 ENOG4105C54 Major Facilitator superfamily A0J50_12925 ENOG4105CVR type I restriction-modification system A0J50_12930 ENOG4107SCJ type I restriction enzyme EcoKI subunit R A0J50_12970 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) A0J50_12975 ENOG4105C0R drug resistance transporter emrb qaca subfamily A0J50_12980 ENOG4105CW7 secretion protein, HlyD family A0J50_12985 ENOG4108VUY thioesterase Superfamily protein A0J50_12990 ENOG4105D52 delta-aminolevulinic acid dehydratase A0J50_12995 ENOG4105MWK D-amino acid dehydrogenase, small subunit A0J50_13000 ENOG4105ECP epimerase A0J50_13020 ENOG4107RH8 nuclease SbcCD subunit D A0J50_13025 ENOG4105EYH Exonuclease A0J50_13030 ENOG4105DFA alanine racemase domain protein A0J50_13035 ENOG4105CZX twitching motility protein A0J50_13040 ENOG4105CZX twitching motility protein A0J50_13045 ENOG41090R7 Ferric uptake A0J50_13055 ENOG4105VDB UPF0125 protein A0J50_13070 ENOG4105E7A Glutamine amidotransferase A0J50_13085 ENOG4107QKV phosphomannomutase A0J50_13095 ENOG4105C4R Atp-dependent dna helicase A0J50_13100 ENOG4108ZG0 Ompa motb domain protein A0J50_13105 ENOG4106HNH Acyl-transferase A0J50_13120 ENOG4107QMS site-determining protein A0J50_13140 ENOG4105CNU cell division protein FtsK A0J50_13145 ENOG4105C3M thioredoxin reductase A0J50_13150 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) A0J50_13160 ENOG4105KEG ribosomal-protein-alanine acetyltransferase A0J50_13175 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) A0J50_13180 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) A0J50_13190 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) A0J50_13205 ENOG4108YXA Membrane A0J50_13215 ENOG4105C4K Nad synthetase A0J50_13230 ENOG4105E3J oxidoreductase A0J50_13235 ENOG4105C26 Dehydrogenase A0J50_13240 ENOG4105DVW rieske (2Fe-2S) A0J50_13250 ENOG4105C94 Transporter A0J50_13255 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) A0J50_13260 ENOG4105EJC lysr family transcriptional regulator A0J50_13280 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding A0J50_13300 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase A0J50_13305 ENOG4105C34 Pseudouridine synthase A0J50_13310 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane A0J50_13330 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) A0J50_13360 ENOG4105C5T Phosphoribosyl pyrophosphate synthase A0J50_13390 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) A0J50_13400 ENOG4105DWF phosphomethylpyrimidine kinase A0J50_13405 ENOG4109066 lysm domain bon superfamily protein A0J50_13415 ENOG4105CHR reductase A0J50_13420 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase A0J50_13430 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein A0J50_13435 ENOG4108BPE -transporting atpase A0J50_13440 ENOG4107RTD sua5 ycio yrdc ywlc family protein A0J50_13445 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) A0J50_13450 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) A0J50_13455 ENOG4105FE9 pseudouridine synthase A0J50_13465 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A0J50_13470 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) A0J50_13480 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) A0J50_13490 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase A0J50_13495 ENOG4106UW1 Major Facilitator superfamily A0J50_13515 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) A0J50_13525 ENOG4105HF0 Membrane A0J50_13540 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY A0J50_13550 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) A0J50_13600 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) A0J50_13605 ENOG4105D1F ATP-binding protein A0J50_13650 ENOG4105K6H D-cysteine desulfhydrase A0J50_13655 ENOG4105CBX hi0933 family A0J50_13675 ENOG4105DP0 ferredoxin-NADP reductase A0J50_13680 ENOG4105DUM transcriptional regulator, lysR family A0J50_13700 ENOG4105C8S subunit m A0J50_13705 ENOG4105D65 subunit l A0J50_13715 ENOG4107UFS subunit j A0J50_13730 ENOG4108IEH NADH dehydrogenase subunit g A0J50_13735 ENOG4107QIZ NADH dehydrogenase A0J50_13740 ENOG4105GKE subunit e A0J50_13760 ENOG4105BZU Histidine kinase A0J50_13770 ENOG4105E0F Histidine kinase A0J50_13775 ENOG4107EXC regulatoR A0J50_13780 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) A0J50_13785 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) A0J50_13835 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) A0J50_13840 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) A0J50_13850 ENOG4105ETT transcriptional Regulator, LysR family A0J50_13895 ENOG4106P55 Transcriptional regulator A0J50_13900 ENOG4107EFR Flavocytochrome c A0J50_13940 ENOG4105ETT transcriptional Regulator, LysR family A0J50_13975 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) A0J50_13980 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) A0J50_13985 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) A0J50_14005 ENOG4105E3B Multicopper oxidase A0J50_14015 ENOG4108HCJ Hydrolase A0J50_14020 ENOG4105DJV ribulose-phosphate 3-epimerase A0J50_14045 ENOG41072GX Peptidase M22 Glycoprotease A0J50_14050 ENOG4108Z0R Transferase A0J50_14095 ENOG4105CRQ synthase (Component I) A0J50_14105 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) A0J50_14110 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) A0J50_14115 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) A0J50_14185 ENOG4105K56 Transcriptional regulator A0J50_14190 ENOG4108ZHJ Organic hydroperoxide resistance protein A0J50_14215 ENOG4105C2M dna polymerase I A0J50_14220 ENOG4108VIA integral membrane protein A0J50_14225 ENOG4105II7 pyrroline-5-carboxylate reductase A0J50_14230 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) A0J50_14240 ENOG4105C9X ppx gppa phosphatase A0J50_14250 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) A0J50_14265 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) A0J50_14280 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) A0J50_14285 ENOG41082NX 50s ribosomal protein l35 A0J50_14300 ENOG4105W39 Membrane A0J50_14305 ENOG4105CYM Glutathione S-transferase A0J50_14325 ENOG4105CEY Amp-dependent synthetase and ligase A0J50_14330 ENOG4105N42 UPF0307 protein A0J50_14335 ENOG41080Z8 PHOSPHOCARRIER protein A0J50_14355 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase A0J50_14360 ENOG4105DJ0 Poly(A) Polymerase A0J50_14365 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein A0J50_14370 ENOG4105DXN mazG family A0J50_14375 ENOG4105EMU Dehydrogenase A0J50_14380 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) A0J50_14395 ENOG4105C6T cysteine synthase A0J50_14400 ENOG4105BZU Histidine kinase A0J50_14405 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase A0J50_14410 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A0J50_14415 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) A0J50_14435 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) A0J50_14440 ENOG4105W8H transhydrogenase (subunit alpha A0J50_14445 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) A0J50_14450 ENOG4106UX7 integral membrane protein A0J50_14485 ENOG4105H3G oxidoreductase A0J50_14490 ENOG4105C3M thioredoxin reductase A0J50_14495 ENOG4105CAU Arsenical resistance protein, ArsH A0J50_14500 ENOG4105D6J arsenicaL-resistance protein A0J50_14510 ENOG4105KBH arsR family transcriptional regulator A0J50_14535 ENOG4105CE1 Ferrous iron transport protein b A0J50_14545 ENOG4108IJF Heavy metal efflux pump, CzcA A0J50_14570 ENOG4105E3B Multicopper oxidase A0J50_14585 ENOG4105GR3 Histidine kinase A0J50_14665 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) A0J50_14675 ENOG4107RSM transcriptional regulator A0J50_14680 ENOG4105CUZ uba thif-type nad fad binding protein A0J50_14690 ENOG4105F8V Hydrolase, tatD family A0J50_14705 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) A0J50_14710 ENOG4107R3N Filamentation induced by cAMP protein fic A0J50_14725 ENOG4107QMH DNA methylase A0J50_14745 ENOG4105F9F transposase A0J50_14755 ENOG4105EUZ Beta-lactamase domain protein A0J50_14760 ENOG4105F9F transposase A0J50_14860 ENOG4105BZU Histidine kinase A0J50_14865 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase A0J50_14870 ENOG4108ZP8 Acetolactate synthase small subunit A0J50_14875 ENOG4105C7K acetolactate synthase A0J50_14895 ENOG4105DJY efflux transporter, rnd family, mfp subunit A0J50_14900 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) A0J50_14905 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A0J50_14910 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH A0J50_14920 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) A0J50_14925 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) A0J50_14935 ENOG4105VW4 glutaredoxin 3 A0J50_14955 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) A0J50_14975 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) A0J50_14995 ENOG4105WVQ Fe-S assembly protein IscX A0J50_15010 ENOG4105CN1 protease A0J50_15025 ENOG4106HB6 Alpha beta hydrolase A0J50_15035 ENOG4105C26 Dehydrogenase A0J50_15040 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family A0J50_15045 ENOG4105C6Z Gluconate A0J50_15050 ENOG4108UHU Aldolase A0J50_15055 ENOG4105C01 Dihydroxy-acid dehydratase A0J50_15060 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) A0J50_15065 ENOG4108DNC Involved in acetate metabolism (By similarity) A0J50_15070 ENOG4107GFK fumarate A0J50_15090 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) A0J50_15100 ENOG4108ESX Receptor A0J50_15110 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) A0J50_15120 ENOG4105DWV Homoserine O-trans-acetylase A0J50_15220 ENOG4105CIY formyltetrahydrofolate deformylase A0J50_15230 ENOG4107RGH Aldehyde dehydrogenase A0J50_15235 ENOG4105KDC 50s ribosomal protein l28 A0J50_15240 ENOG4105W0E 50S ribosomal protein L33 A0J50_15245 ENOG4105CKD glutathione-regulated potassium-efflux system protein A0J50_15250 ENOG4105CKD glutathione-regulated potassium-efflux system protein A0J50_15270 ENOG4105VFU Rna-binding protein A0J50_15275 ENOG4105C4R Atp-dependent dna helicase A0J50_15290 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) A0J50_15300 ENOG4105KVH Transcriptional regulator A0J50_15310 ENOG41069P5 Protein slyX homolog A0J50_15315 ENOG4105C5H ABC transporter A0J50_15325 ENOG4105D1S lipid A biosynthesis A0J50_15335 ENOG4105CK2 sodium dicarboxylate symporter A0J50_15390 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) A0J50_15440 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase A0J50_15455 ENOG4108W5M transcriptional regulator A0J50_15470 ENOG4105D29 Helix-turn-helix type 11 domain protein A0J50_15475 ENOG4107XGZ Hydrolase A0J50_15480 ENOG4105EI2 Pseudouridine synthase A0J50_15485 ENOG4105C03 ribonuclease A0J50_15515 ENOG4105CSA Coproporphyrinogen iii oxidase A0J50_15525 ENOG4107QI1 Mate efflux family protein A0J50_15535 ENOG4107T8P acyl-Coa dehydrogenase A0J50_15565 ENOG4105BZ8 glutamate synthase A0J50_15575 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) A0J50_15580 ENOG4105C5X domain protein A0J50_15595 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) A0J50_15605 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase A0J50_15615 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) A0J50_15620 ENOG4108JU5 Magnesium and cobalt efflux protein A0J50_15625 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) A0J50_15630 ENOG4108Z7R Chaperone CsaA A0J50_15640 ENOG4108VAU general secretion pathway protein G A0J50_15645 ENOG4105D7Q type ii secretion system A0J50_15660 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) A0J50_15675 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) A0J50_15680 ENOG4107QUT magnesium and cobalt transport protein CorA A0J50_15685 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) A0J50_15700 ENOG4107QYX exodeoxyribonuclease v alpha A0J50_15705 ENOG4107QKA exodeoxyribonuclease V beta A0J50_15710 ENOG4105DSY exodeoxyribonuclease V, gamma A0J50_15720 ENOG4105CSR polyphosphate kinase 2 A0J50_15730 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) A0J50_15750 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase A0J50_15775 ENOG4108ZE9 Monovalent cation H antiporter subunit C A0J50_15780 ENOG4107R4Z monovalent cation h antiporter subunit d A0J50_15785 ENOG4105SC1 monovalent cation H antiporter subunit E A0J50_15790 ENOG4105W4C monovalent cation H antiporter subunit F A0J50_15795 ENOG4105KJM monovalent cation h antiporter subunit g A0J50_15800 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) A0J50_15810 ENOG4105CHV Transcription elongation factor NusA A0J50_15835 ENOG4107EJC Preprotein translocase subunit SecG A0J50_15845 ENOG4107QHF type ii secretion system protein e A0J50_15860 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) A0J50_15870 ENOG4105C2N RNA methyltransferase TrmH family group 3 A0J50_15885 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) A0J50_15895 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) A0J50_15925 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) A0J50_15930 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase A0J50_16000 ENOG4108Z6Z Transcriptional regulator A0J50_16010 ENOG4107ZXU DSBA oxidoreductase A0J50_16025 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) A0J50_16040 ENOG4105D3Y Na H antiporter A0J50_16095 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) A0J50_16100 ENOG4105PM1 preprotein translocase subunit SecE A0J50_16110 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) A0J50_16140 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) A0J50_16165 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS A0J50_16170 ENOG4105F9F transposase A0J50_16195 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) A0J50_16200 ENOG4108NEV two component transcriptional regulator, LytTR family A0J50_16205 ENOG4108HRK Histidine kinase A0J50_16220 ENOG4108UTW Plays a role in the regulation of phosphate uptake A0J50_16225 ENOG4105DFG type I secretion outer membrane protein A0J50_16230 ENOG4108RNG Permease of the drug metabolite transporter A0J50_16255 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) A0J50_16260 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters A0J50_16265 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) A0J50_16270 ENOG4105CNI cell division protein FtsW A0J50_16285 ENOG4105CE1 Ferrous iron transport protein b A0J50_16295 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) A0J50_16300 ENOG4105T95 Thiol disulfide interChange protein A0J50_16305 ENOG4105D6E homoserine dehydrogenase A0J50_16315 ENOG41061WM D-Alanyl-D-Alanine A0J50_16325 ENOG4107TUY Histidine kinase A0J50_16330 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family A0J50_16335 ENOG4105CN1 protease A0J50_16340 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) A0J50_16345 ENOG4108K5H permease YjgP YjgQ family protein A0J50_16385 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) A0J50_16395 ENOG4105BZU Histidine kinase A0J50_16460 ENOG4105PGM cation diffusion facilitator family transporter A0J50_16475 ENOG4105ENJ RND efflux system, outer membrane lipoprotein A0J50_16485 ENOG4105C1P efflux transporter, rnd family, mfp subunit A0J50_16490 ENOG4105PGM cation diffusion facilitator family transporter A0J50_16540 ENOG4107Y80 Major Facilitator superfamily A0J50_16580 ENOG4108ZIT Ferredoxin, 2FE-2S A0J50_16630 ENOG4108YYH Nadph-dependent fmn reductase A0J50_16640 ENOG4105FB2 class II Aldolase A0J50_16660 ENOG41090KI Outer membrane porin A0J50_16665 ENOG4105F0N pyrophosphate phospho-hydrolase A0J50_16680 ENOG4105CEY Amp-dependent synthetase and ligase A0J50_16695 ENOG4105EN6 Membrane A0J50_16705 ENOG4105EE5 Membrane protein terC A0J50_16710 ENOG4108URH decarboxylase A0J50_16725 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) A0J50_16740 ENOG4105CCT upf0313 protein A0J50_16760 ENOG4105CS1 NAD(P)H quinone oxidoreductase A0J50_16805 ENOG4105Y7M Transcriptional regulator, TetR family A0J50_16840 ENOG4105C79 DNA protecting protein DprA A0J50_16860 ENOG4107RTG Major Facilitator superfamily A0J50_16870 ENOG4108V06 Glutathione peroxidase A0J50_16885 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) A0J50_16895 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) A0J50_16910 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) A0J50_16935 ENOG4105FDK ABC transporter A0J50_16940 ENOG4105FAV ABC, transporter A0J50_16950 ENOG4105EZR dyp-type peroxidase family protein A0J50_16955 ENOG4107R1I NAD-dependent malic enzyme A0J50_16980 ENOG4105EUB pirin domain protein A0J50_17005 ENOG4106MP8 UPF0754 membrane protein A0J50_17010 ENOG4108VBZ doxx family A0J50_17015 ENOG4105DQR SNARE associated Golgi A0J50_17030 ENOG4107QJE Chromosome Partitioning Protein A0J50_17040 ENOG4107PSF BolA-like protein A0J50_17115 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family A0J50_17125 ENOG4105CJP fad dependent oxidoreductase A0J50_17130 ENOG4105C85 amino acid A0J50_17135 ENOG4108594 Permease of the drug metabolite transporter A0J50_17140 ENOG4105CSH Transporter A0J50_17145 ENOG4105E39 Enoyl-CoA hydratase A0J50_17150 ENOG4105E39 Enoyl-CoA hydratase A0J50_17155 ENOG4105C1G acyl-Coa dehydrogenase A0J50_17165 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase A0J50_17170 ENOG4105C26 Dehydrogenase A0J50_17180 ENOG4105C85 amino acid A0J50_17185 ENOG4105C85 amino acid A0J50_17190 ENOG4105M4H endoribonuclease L-psp A0J50_17230 ENOG4105D3G Pseudouridine synthase A0J50_17250 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) A0J50_17255 ENOG4105CIS alcohol dehydrogenase A0J50_17295 ENOG4108I0Z Aconitate hydratase A0J50_17300 ENOG4105BZN citrate synthase A0J50_17305 ENOG4105CR4 methylisocitrate lyase A0J50_17310 ENOG4105DRR Transcriptional regulator, GntR family A0J50_17315 ENOG4105CGF Aromatic amino acid aminotransferase A0J50_17320 ENOG4105CXG d-lactate dehydrogenase A0J50_17330 ENOG41073TP transcriptional regulator A0J50_17335 ENOG4105DAA L-lactate A0J50_17340 ENOG4107QKV phosphomannomutase A0J50_17350 ENOG4105C6Y Udp-glucose 6-dehydrogenase A0J50_17355 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase A0J50_17360 ENOG4105D3Q Sugar transferase A0J50_17390 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase A0J50_17400 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase A0J50_17415 ENOG4105PSV Polysaccharide Biosynthesis Protein A0J50_17430 ENOG4107QQG Dehydrogenase A0J50_17435 ENOG4105DAY polysaccharide export protein A0J50_17445 ENOG4105D75 Capsular exopolysaccharide family A0J50_17450 ENOG4108V1T peptidylprolyl cis-trans isomerase A0J50_17455 ENOG4108V1T peptidylprolyl cis-trans isomerase A0J50_17460 ENOG4105CJR Integral membrane protein (MviN A0J50_17465 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase A0J50_17470 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase A0J50_17475 ENOG4105HSS phospholipase C A0J50_17500 ENOG41062JF Transcriptional regulator A0J50_17515 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) A0J50_17520 ENOG4105UBK short-chain dehydrogenase reductase A0J50_17535 ENOG4107QZM n-acetylglutamate synthase A0J50_17540 ENOG4105GVF (ABC) transporter A0J50_17545 ENOG4105GVF (ABC) transporter A0J50_17550 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) A0J50_17555 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component A0J50_17560 ENOG4108VM9 ABC, transporter A0J50_17565 ENOG4108R86 Transcriptional regulator A0J50_17570 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) A0J50_17580 ENOG4105DTN riboflavin biosynthesis protein ribF A0J50_17585 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) A0J50_17595 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase A0J50_17635 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) A0J50_17695 ENOG4105CVE Lytic murein transglycosylase A0J50_17700 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit A0J50_17705 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) A0J50_17715 ENOG4105DFU Cell wall formation (By similarity) A0J50_17725 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase A0J50_17730 ENOG4105DU1 integral membrane protein, terc A0J50_17740 ENOG4106032 Glutathionylspermidine synthase A0J50_17750 ENOG4107QUY Guanine deaminase A0J50_17755 ENOG4108UGV hypoxanthine phosphoribosyltransferase A0J50_17765 ENOG4105T95 Thiol disulfide interChange protein A0J50_17785 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins A0J50_17800 ENOG4105VG0 50S ribosomal protein l34 A0J50_17810 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) A0J50_17820 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) A0J50_17835 ENOG4105C5H ABC transporter A0J50_17840 ENOG4108821 RND type efflux pump A0J50_17845 ENOG4108821 RND type efflux pump A0J50_17850 ENOG4108821 RND type efflux pump A0J50_17860 ENOG4105D74 hydrolase A0J50_17865 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) A0J50_17870 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) A0J50_17910 ENOG4105C8J )-transporter A0J50_17915 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B A0J50_17945 ENOG4105C2W permease A0J50_17955 ENOG4108IG5 Transcriptional regulator A0J50_17960 ENOG4105DJY efflux transporter, rnd family, mfp subunit A0J50_18055 ENOG4105MRD Phage derived protein Gp49-like (DUF891) A0J50_18095 ENOG4105XUP Phage derived protein Gp49-like (DUF891) A0J50_18125 ENOG4105EMU Dehydrogenase A0J50_18130 ENOG4108PZW LysR family Transcriptional regulator A0J50_18135 ENOG4107QPD alcohol dehydrogenase A0J50_18140 ENOG4108JA1 polyketide synthase A0J50_18155 ENOG4105C4W S-formylglutathione hydrolase A0J50_18165 ENOG4108I6A alcohol dehydrogenase A0J50_18175 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A0J50_18185 ENOG4108WUH Transcriptional regulator, TetR family A0J50_18190 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein A0J50_18200 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium A0J50_18310 ENOG4105VT2 5-hydroxyisourate hydrolase A0J50_18315 ENOG4105C2W permease A0J50_18330 ENOG4105DHG Allantoate amidinohydrolase A0J50_18335 ENOG41061H0 Monooxygenase A0J50_18340 ENOG4105SKE transcriptional Regulator LysR family A0J50_18350 ENOG4105C2W permease A0J50_18355 ENOG4105DRB nucleoside-specific channel-forming protein A0J50_18370 ENOG4105RQF LysR family Transcriptional regulator A0J50_18410 ENOG4105MP0 transposase A0J50_18455 ENOG4108R6W Transcriptional regulator, ARAC family A0J50_18460 ENOG4107Z7P Ferredoxin A0J50_18490 ENOG4108RZE Tetr family transcriptional regulator A0J50_18625 ENOG4105E4P ATPase (AAA A0J50_18725 ENOG4105MZU cell filamentation protein A0J50_18800 ENOG4105G6Z alkaline phosphatase A0J50_18805 ENOG4105FA0 parb-like partition protein A0J50_18810 ENOG4107QJE Chromosome Partitioning Protein A0J50_18835 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family A0J50_18865 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium A0J50_18875 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein A0J50_18880 ENOG4108WUH Transcriptional regulator, TetR family A0J50_18890 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase A0J50_18900 ENOG4108I6A alcohol dehydrogenase A0J50_18910 ENOG4105C4W S-formylglutathione hydrolase A0J50_18925 ENOG4105ECQ AraC Family Transcriptional Regulator A0J50_18935 ENOG4105CSH Transporter A0J50_18940 ENOG4105RPH Inner membrane protein YddG A0J50_18945 ENOG4108JA1 polyketide synthase A0J50_18950 ENOG4107QPD alcohol dehydrogenase A0J50_18955 ENOG4105EJC lysr family transcriptional regulator A0J50_18960 ENOG4105EMU Dehydrogenase A0J50_19030 ENOG4105MRD Phage derived protein Gp49-like (DUF891) A0J50_19070 ENOG4105XUP Phage derived protein Gp49-like (DUF891) A0J50_19130 ENOG4105XUP Phage derived protein Gp49-like (DUF891) A0J50_19160 ENOG4105CHH sulfate transporter