locus-tag	class	description
A0J50_00055	COG2233	PERMEase
A0J50_00105	COG2814	Major facilitator Superfamily
A0J50_00110	COG0656	L-ascorbic acid biosynthetic process
A0J50_00115	COG0583	DNA-binding transcription factor activity
A0J50_00125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_00130	COG1064	alcohol dehydrogenase
A0J50_00135	COG2818	Glycosylase
A0J50_00150	COG1194	a g-specific adenine glycosylase
A0J50_00165	COG2983	Belongs to the UPF0260 family
A0J50_00170	COG2133	pyrroloquinoline quinone binding
A0J50_00175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A0J50_00180	COG2116	formate transmembrane transporter activity
A0J50_00200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0J50_00205	COG1335	isochorismatase
A0J50_00210	COG0385	Bile acid
A0J50_00215	COG0534	Mate efflux family protein
A0J50_00220	COG1683	Conserved Protein
A0J50_00235	COG0346	lactoylglutathione lyase activity
A0J50_00240	COG0625	glutathione transferase activity
A0J50_00250	COG1113	amino acid transport
A0J50_00270	COG2188	Transcriptional regulator
A0J50_00300	COG0010	Belongs to the arginase family
A0J50_00365	COG0546	phosphoglycolate phosphatase activity
A0J50_00370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0J50_00380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A0J50_00390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A0J50_00395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A0J50_00505	COG2733	membrane
A0J50_00520	COG2918	glutathione biosynthetic process
A0J50_00530	COG3501	Rhs element vgr protein
A0J50_00535	COG1705	Flagellar rod assembly protein muramidase FlgJ
A0J50_00535	COG1388	LysM domain
A0J50_00555	COG3150	esterase
A0J50_00565	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
A0J50_00575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0J50_00585	COG2233	PERMEase
A0J50_00590	COG2351	hydroxyisourate hydrolase activity
A0J50_00640	COG1393	Belongs to the ArsC family
A0J50_00645	COG0708	Exodeoxyribonuclease III
A0J50_00665	COG0189	ligase activity
A0J50_00685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A0J50_00695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A0J50_00710	COG4942	peptidase
A0J50_00720	COG0508	dehydrogenase complex catalyzes the overall conversion of
A0J50_00730	COG2119	membrane
A0J50_00735	COG4774	siderophore transport
A0J50_00740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0J50_00740	COG0426	domain, Protein
A0J50_00760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A0J50_00780	COG1902	pentaerythritol trinitrate reductase activity
A0J50_00790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A0J50_00815	COG1522	sequence-specific DNA binding
A0J50_00845	COG3162	membrane
A0J50_00850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0J50_00860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A0J50_00870	COG3706	GGDEF domain
A0J50_00880	COG1309	transcriptional regulator
A0J50_00900	COG0300	oxidoreductase activity
A0J50_00905	COG0789	Transcriptional regulator
A0J50_00910	COG0351	phosphomethylpyrimidine kinase
A0J50_00910	COG0352	thiamine-phosphate diphosphorylase activity
A0J50_00910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A0J50_00920	COG2814	Major facilitator Superfamily
A0J50_00935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A0J50_00945	COG1113	amino acid transport
A0J50_00960	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_00970	COG1335	isochorismatase
A0J50_01000	COG2814	Major facilitator Superfamily
A0J50_01005	COG0583	DNA-binding transcription factor activity
A0J50_01025	COG0667	Aldo Keto reductase
A0J50_01055	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_01060	COG1733	regulation of RNA biosynthetic process
A0J50_01065	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0J50_01090	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_01150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A0J50_01165	COG2329	Antibiotic biosynthesis monooxygenase
A0J50_01170	COG0697	spore germination
A0J50_01185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A0J50_01195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A0J50_01225	COG0427	acetyl-CoA hydrolase
A0J50_01230	COG2205	protein histidine kinase activity
A0J50_01235	COG0745	RESPONSE REGULATOR receiver
A0J50_01250	COG4221	oxidoreductase activity
A0J50_01260	COG0488	(ABC) transporter
A0J50_01340	COG0833	amino acid
A0J50_01385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A0J50_01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A0J50_01405	COG2226	methyltransferase
A0J50_01455	COG0067	glutamate synthase
A0J50_01455	COG0070	glutamate synthase
A0J50_01455	COG0069	glutamate synthase activity
A0J50_01470	COG1704	LemA family
A0J50_01475	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A0J50_01500	COG3307	-O-antigen
A0J50_01520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A0J50_01530	COG0194	GDP metabolic process
A0J50_01580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A0J50_01590	COG0335	large ribosomal subunit rRNA binding
A0J50_01600	COG5380	lipid catabolic process
A0J50_01605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A0J50_01620	COG5006	permease, DMT superfamily
A0J50_01625	COG5006	permease, DMT superfamily
A0J50_01630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0J50_01635	COG0277	FAD linked oxidase domain protein
A0J50_01645	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A0J50_01650	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0J50_01665	COG1289	transmembrane transporter activity
A0J50_01675	COG0628	permease
A0J50_01680	COG1192	Involved in chromosome partitioning
A0J50_01710	COG0833	amino acid
A0J50_01715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0J50_01720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0J50_01730	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_01770	COG0583	DNA-binding transcription factor activity
A0J50_01795	COG0752	glycyl-tRNA synthetase alpha subunit
A0J50_01825	COG1983	PspC domain protein
A0J50_01835	COG1960	acyl-CoA dehydrogenase activity
A0J50_01850	COG0408	coproporphyrinogen oxidase activity
A0J50_01870	COG0513	Belongs to the DEAD box helicase family
A0J50_01880	COG1127	ABC transporter
A0J50_01885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A0J50_01895	COG2854	intermembrane phospholipid transfer
A0J50_01905	COG0598	Magnesium transport protein CorA
A0J50_01915	COG0494	nUDIX hydrolase
A0J50_01920	COG1040	competence protein
A0J50_01940	COG2937	Belongs to the GPAT DAPAT family
A0J50_01945	COG1946	Acyl-CoA thioesterase
A0J50_01950	COG1301	dicarboxylic acid transport
A0J50_01965	COG1959	2 iron, 2 sulfur cluster binding
A0J50_01970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0J50_01970	COG1017	nitric oxide dioxygenase activity
A0J50_01975	COG0433	COG0433 Predicted ATPase
A0J50_01980	COG0626	cystathionine gamma-synthase activity
A0J50_01995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A0J50_02000	COG0088	Forms part of the polypeptide exit tunnel
A0J50_02100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A0J50_02110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A0J50_02135	COG1960	acyl-CoA dehydrogenase activity
A0J50_02140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A0J50_02170	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A0J50_02175	COG0339	signal peptide processing
A0J50_02180	COG0557	exoribonuclease II activity
A0J50_02230	COG0179	Fumarylacetoacetate (FAA) hydrolase
A0J50_02310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A0J50_02315	COG1183	phosphatidylcholine synthase activity
A0J50_02360	COG1960	acyl-CoA dehydrogenase activity
A0J50_02365	COG1309	transcriptional regulator
A0J50_02380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0J50_02385	COG1960	acyl-CoA dehydrogenase activity
A0J50_02425	COG2969	positive regulation of protein catabolic process
A0J50_02435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A0J50_02440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A0J50_02445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A0J50_02450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A0J50_02455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A0J50_02475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A0J50_02485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A0J50_02490	COG1408	metallophosphoesterase
A0J50_02495	COG2885	chlorophyll binding
A0J50_02495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A0J50_02500	COG2199	diguanylate cyclase activity
A0J50_02550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0J50_02550	COG3453	Protein conserved in bacteria
A0J50_02575	COG1607	acyl-coa hydrolase
A0J50_02610	COG2350	Protein conserved in bacteria
A0J50_02625	COG3781	membrane
A0J50_02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A0J50_02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A0J50_02650	COG1862	Preprotein translocase
A0J50_02695	COG0784	Response regulator, receiver
A0J50_02695	COG2205	protein histidine kinase activity
A0J50_02695	COG5002	protein histidine kinase activity
A0J50_02715	COG0726	polysaccharide deacetylase
A0J50_02730	COG1216	Glycosyl transferase, family 2
A0J50_02780	COG0625	glutathione transferase activity
A0J50_02785	COG0583	DNA-binding transcription factor activity
A0J50_02795	COG1960	acyl-CoA dehydrogenase activity
A0J50_02805	COG2205	protein histidine kinase activity
A0J50_02810	COG0745	RESPONSE REGULATOR receiver
A0J50_02820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A0J50_02840	COG2096	Adenosyltransferase
A0J50_02855	COG0133	tryptophan synthase activity
A0J50_02890	COG0285	dihydrofolate synthase activity
A0J50_02910	COG0450	alkyl hydroperoxide reductase
A0J50_02925	COG0477	Major facilitator Superfamily
A0J50_02930	COG1272	protein, Hemolysin III
A0J50_02940	COG2153	protein acetylation
A0J50_02960	COG0183	Belongs to the thiolase family
A0J50_02965	COG2207	Transcriptional regulator
A0J50_02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0J50_03005	COG0183	Belongs to the thiolase family
A0J50_03015	COG2885	chlorophyll binding
A0J50_03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A0J50_03020	COG1690	Belongs to the RtcB family
A0J50_03035	COG2233	PERMEase
A0J50_03065	COG2094	Belongs to the DNA glycosylase MPG family
A0J50_03080	COG0679	Auxin Efflux Carrier
A0J50_03090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A0J50_03095	COG0354	folic acid binding
A0J50_03110	COG2233	PERMEase
A0J50_03115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0J50_03120	COG0251	oxidation-reduction process
A0J50_03125	COG1335	isochorismatase
A0J50_03130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0J50_03140	COG0596	Alpha beta hydrolase
A0J50_03145	COG3189	MarR family transcriptional regulator
A0J50_03150	COG2824	Alkylphosphonate utilization operon protein PhnA
A0J50_03155	COG3422	double-strand break repair
A0J50_03195	COG0840	transmembrane signaling receptor activity
A0J50_03215	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_03225	COG5510	response to toxic substance
A0J50_03235	COG2832	Protein of unknown function (DUF454)
A0J50_03240	COG1376	ErfK ybiS ycfS ynhG family protein
A0J50_03280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A0J50_03290	COG1289	transmembrane transporter activity
A0J50_03295	COG2814	Major facilitator Superfamily
A0J50_03310	COG1115	amino acid carrier protein
A0J50_03320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A0J50_03325	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A0J50_03365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A0J50_03370	COG1077	Cell shape determining protein MreB Mrl
A0J50_03380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A0J50_03385	COG0424	maF-like protein
A0J50_03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0J50_03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
A0J50_03440	COG2207	Transcriptional regulator
A0J50_03465	COG3046	protein related to deoxyribodipyrimidine photolyase
A0J50_03475	COG1113	amino acid transport
A0J50_03485	COG0142	geranyltranstransferase activity
A0J50_03490	COG2315	Protein conserved in bacteria
A0J50_03505	COG1752	Esterase of the alpha-beta hydrolase superfamily
A0J50_03530	COG2194	sulfuric ester hydrolase activity
A0J50_03535	COG0745	RESPONSE REGULATOR receiver
A0J50_03540	COG0642	Histidine kinase
A0J50_03550	COG0004	ammonium transporteR
A0J50_03555	COG0583	DNA-binding transcription factor activity
A0J50_03585	COG0525	valine-tRNA ligase activity
A0J50_03595	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_03605	COG0393	Putative heavy-metal-binding
A0J50_03610	COG0393	Putative heavy-metal-binding
A0J50_03615	COG1538	Outer membrane efflux protein
A0J50_03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_03630	COG0671	phosphoesterase, PA-phosphatase related
A0J50_03655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A0J50_03675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A0J50_03710	COG0531	amino acid
A0J50_03725	COG0321	lipoyl(octanoyl) transferase activity
A0J50_03730	COG2921	Belongs to the UPF0250 family
A0J50_03770	COG2009	succinate dehydrogenase
A0J50_03775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A0J50_03780	COG1053	succinate dehydrogenase
A0J50_03785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A0J50_03805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0J50_03825	COG2354	Protein conserved in bacteria
A0J50_03850	COG2843	Capsule synthesis protein
A0J50_03870	COG0589	response to stress
A0J50_03880	COG0251	oxidation-reduction process
A0J50_03885	COG1309	transcriptional regulator
A0J50_03900	COG0505	Belongs to the CarA family
A0J50_03925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0J50_03930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A0J50_03980	COG0477	Major facilitator Superfamily
A0J50_04005	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A0J50_04050	COG0584	glycerophosphoryl diester phosphodiesterase
A0J50_04070	COG0741	lytic transglycosylase activity
A0J50_04090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A0J50_04100	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_04110	COG0583	DNA-binding transcription factor activity
A0J50_04135	COG0406	alpha-ribazole phosphatase activity
A0J50_04155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_04165	COG0778	Nitroreductase
A0J50_04185	COG0243	molybdopterin cofactor binding
A0J50_04190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A0J50_04205	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A0J50_04245	COG1280	lysine exporter protein (LysE YggA)
A0J50_04310	COG4591	ABC-type transport system involved in lipoprotein release permease component
A0J50_04315	COG1136	(ABC) transporter
A0J50_04330	COG0616	signal peptide processing
A0J50_04330	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A0J50_04335	COG0596	Alpha beta hydrolase
A0J50_04340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A0J50_04350	COG0628	permease
A0J50_04385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0J50_04405	COG0823	Involved in the tonB-independent uptake of proteins
A0J50_04425	COG0824	Thioesterase
A0J50_04430	COG1473	amidohydrolase
A0J50_04450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A0J50_04450	COG0047	phosphoribosylformylglycinamidine synthase activity
A0J50_04455	COG2814	Major facilitator Superfamily
A0J50_04460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A0J50_04465	COG1024	Enoyl-CoA hydratase
A0J50_04470	COG1056	cytidyltransferase-related domain
A0J50_04470	COG1051	belongs to the nudix hydrolase family
A0J50_04485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0J50_04500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A0J50_04515	COG4625	pathogenesis
A0J50_04520	COG0583	DNA-binding transcription factor activity
A0J50_04525	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A0J50_04530	COG4208	sulfate ABC transporter
A0J50_04535	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A0J50_04545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A0J50_04550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A0J50_04555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A0J50_04575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0J50_04585	COG0481	GTPase activity
A0J50_04590	COG0681	Belongs to the peptidase S26 family
A0J50_04600	COG0571	ribonuclease III activity
A0J50_04605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A0J50_04615	COG1381	Involved in DNA repair and RecF pathway recombination
A0J50_04620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A0J50_04630	COG4221	oxidoreductase activity
A0J50_04675	COG0556	nucleotide-excision repair
A0J50_04685	COG2962	Rard protein
A0J50_04730	COG2070	2-Nitropropane dioxygenase
A0J50_04750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A0J50_04790	COG1252	NADH dehydrogenase
A0J50_04795	COG1686	Belongs to the peptidase S11 family
A0J50_04810	COG1187	pseudouridine synthase activity
A0J50_04825	COG0583	DNA-binding transcription factor activity
A0J50_04840	COG0612	Peptidase, M16
A0J50_04900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0J50_04915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A0J50_04920	COG0076	glutamate decarboxylase activity
A0J50_04930	COG1522	sequence-specific DNA binding
A0J50_04940	COG1113	amino acid transport
A0J50_04945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A0J50_04960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A0J50_04965	COG0616	signal peptide processing
A0J50_05005	COG1686	Belongs to the peptidase S11 family
A0J50_05030	COG0583	DNA-binding transcription factor activity
A0J50_05035	COG1067	ATP-dependent peptidase activity
A0J50_05070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A0J50_05075	COG1966	Carbon starvation protein
A0J50_05080	COG2879	small protein
A0J50_05115	COG1741	Belongs to the pirin family
A0J50_05130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A0J50_05135	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A0J50_05140	COG4605	iron ion homeostasis
A0J50_05145	COG4604	ABC transporter, ATP-binding protein
A0J50_05150	COG4607	ABC-type enterochelin transport system periplasmic component
A0J50_05155	COG4774	siderophore transport
A0J50_05175	COG1535	isochorismatase
A0J50_05175	COG3433	isochorismatase activity
A0J50_05185	COG1132	(ABC) transporter
A0J50_05195	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A0J50_05205	COG1169	isochorismate synthase
A0J50_05220	COG3739	integral membrane protein
A0J50_05240	COG0302	gtp cyclohydrolase
A0J50_05260	COG2840	Smr protein MutS2
A0J50_05285	COG0512	Glutamine amidotransferase of anthranilate synthase
A0J50_05295	COG3104	oligopeptide transport
A0J50_05310	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A0J50_05345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A0J50_05350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A0J50_05355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A0J50_05375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A0J50_05380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A0J50_05405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A0J50_05410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0J50_05420	COG2223	nitrite transmembrane transporter activity
A0J50_05430	COG0024	Methionine aminopeptidase
A0J50_05435	COG0052	Belongs to the universal ribosomal protein uS2 family
A0J50_05450	COG2207	Transcriptional regulator
A0J50_05475	COG2951	lytic endotransglycosylase activity
A0J50_05480	COG0772	Belongs to the SEDS family
A0J50_05495	COG0842	Transport permease protein
A0J50_05500	COG1131	(ABC) transporter
A0J50_05530	COG1538	Outer membrane efflux protein
A0J50_05540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0J50_05555	COG4215	(ABC) transporter
A0J50_05560	COG4160	amino acid transport
A0J50_05565	COG4598	ABC transporter
A0J50_05575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A0J50_05585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_05590	COG0384	phenazine biosynthesis protein PhzF
A0J50_05600	COG1720	tRNA m6t6A37 methyltransferase activity
A0J50_05620	COG0745	RESPONSE REGULATOR receiver
A0J50_05625	COG0642	Histidine kinase
A0J50_05635	COG0494	nUDIX hydrolase
A0J50_05645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A0J50_05650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A0J50_05655	COG3139	Protein of unknown function (DUF1315)
A0J50_05660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A0J50_05670	COG1960	acyl-CoA dehydrogenase activity
A0J50_05685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A0J50_05695	COG2195	Cleaves the N-terminal amino acid of tripeptides
A0J50_05700	COG1234	tRNA 3'-trailer cleavage
A0J50_05725	COG2363	Small membrane protein
A0J50_05745	COG0513	Belongs to the DEAD box helicase family
A0J50_05755	COG0778	Nitroreductase
A0J50_05815	COG1610	YqeY-like protein
A0J50_05820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A0J50_05845	COG2815	serine threonine protein kinase
A0J50_05845	COG0515	serine threonine protein kinase
A0J50_05870	COG1278	Cold shock
A0J50_05890	COG3243	poly(R)-hydroxyalkanoic acid synthase
A0J50_05895	COG0786	glutamate:sodium symporter activity
A0J50_05900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A0J50_05900	COG0475	glutathione-regulated potassium exporter activity
A0J50_05925	COG2985	domain, Protein
A0J50_05935	COG2995	paraquat-inducible protein a
A0J50_05940	COG3008	intermembrane lipid transfer
A0J50_05940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A0J50_05965	COG2351	hydroxyisourate hydrolase activity
A0J50_06020	COG0642	Histidine kinase
A0J50_06025	COG0745	RESPONSE REGULATOR receiver
A0J50_06040	COG1794	racemase activity, acting on amino acids and derivatives
A0J50_06050	COG2175	clavaminate synthase activity
A0J50_06055	COG3246	L-lysine catabolic process to acetate
A0J50_06060	COG2814	Major facilitator Superfamily
A0J50_06075	COG2855	membrane
A0J50_06100	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_06115	COG2814	Major facilitator Superfamily
A0J50_06140	COG1301	dicarboxylic acid transport
A0J50_06150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0J50_06155	COG2011	ABC-type metal ion transport system permease component
A0J50_06160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A0J50_06170	COG0151	Belongs to the GarS family
A0J50_06180	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A0J50_06210	COG2308	Evidence 4 Homologs of previously reported genes of
A0J50_06220	COG1305	Transglutaminase-like
A0J50_06230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A0J50_06235	COG0305	Participates in initiation and elongation during chromosome replication
A0J50_06260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A0J50_06265	COG1845	cytochrome c oxidase, subunit III
A0J50_06270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A0J50_06310	COG1215	transferase activity, transferring glycosyl groups
A0J50_06315	COG3658	cytochrome
A0J50_06325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0J50_06340	COG0583	DNA-binding transcription factor activity
A0J50_06355	COG2890	protein-(glutamine-N5) methyltransferase activity
A0J50_06360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0J50_06365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0J50_06390	COG1960	acyl-CoA dehydrogenase activity
A0J50_06395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0J50_06410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A0J50_06420	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A0J50_06425	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A0J50_06435	COG2205	protein histidine kinase activity
A0J50_06445	COG0174	glutamine synthetase
A0J50_06495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0J50_06500	COG2814	Major facilitator Superfamily
A0J50_06515	COG0583	DNA-binding transcription factor activity
A0J50_06540	COG1187	pseudouridine synthase activity
A0J50_06555	COG0564	pseudouridine synthase activity
A0J50_06560	COG0802	atpase or kinase
A0J50_06565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A0J50_06575	COG1923	regulation of RNA biosynthetic process
A0J50_06580	COG0697	spore germination
A0J50_06595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0J50_06605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0J50_06610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A0J50_06610	COG0519	Catalyzes the synthesis of GMP from XMP
A0J50_06615	COG4302	ethanolamine ammonia-lyase activity
A0J50_06620	COG4303	Ethanolamine ammonia lyase large subunit
A0J50_06645	COG1454	alcohol dehydrogenase
A0J50_06650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A0J50_06720	COG1605	Chorismate mutase
A0J50_06735	COG4772	TonB-dependent receptor
A0J50_06740	COG4774	siderophore transport
A0J50_06795	COG3772	lysozyme
A0J50_06820	COG0583	DNA-binding transcription factor activity
A0J50_06845	COG0488	(ABC) transporter
A0J50_06850	COG0589	response to stress
A0J50_06865	COG3135	benzoate transporter
A0J50_06870	COG1522	sequence-specific DNA binding
A0J50_06880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A0J50_06885	COG0583	DNA-binding transcription factor activity
A0J50_06895	COG0183	Belongs to the thiolase family
A0J50_06945	COG0824	Thioesterase
A0J50_06950	COG1454	alcohol dehydrogenase
A0J50_06985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A0J50_07015	COG0069	glutamate synthase activity
A0J50_07045	COG2814	Major facilitator Superfamily
A0J50_07060	COG0511	ligase activity, forming carbon-carbon bonds
A0J50_07085	COG4264	IucA IucC family
A0J50_07095	COG4264	IucA IucC family
A0J50_07100	COG2423	ornithine cyclodeaminase activity
A0J50_07105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0J50_07110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0J50_07110	COG1116	anion transmembrane transporter activity
A0J50_07125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0J50_07125	COG2146	nitrite reductase [NAD(P)H] activity
A0J50_07130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0J50_07135	COG0243	molybdopterin cofactor binding
A0J50_07150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A0J50_07165	COG0315	cyclic pyranopterin monophosphate synthase activity
A0J50_07165	COG0521	Mo-molybdopterin cofactor biosynthetic process
A0J50_07170	COG0303	'Molybdopterin
A0J50_07180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_07185	COG0697	spore germination
A0J50_07210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A0J50_07275	COG2204	response regulator
A0J50_07280	COG3852	Histidine kinase
A0J50_07300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A0J50_07305	COG0575	Belongs to the CDS family
A0J50_07340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0J50_07355	COG2137	regulation of response to DNA damage stimulus
A0J50_07365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A0J50_07370	COG1011	Hydrolase
A0J50_07385	COG1522	sequence-specific DNA binding
A0J50_07395	COG1113	amino acid transport
A0J50_07415	COG0659	secondary active sulfate transmembrane transporter activity
A0J50_07455	COG1105	Belongs to the carbohydrate kinase PfkB family
A0J50_07460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A0J50_07460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A0J50_07480	COG3193	protein, possibly involved in utilization of glycolate and propanediol
A0J50_07490	COG0024	Methionine aminopeptidase
A0J50_07495	COG0583	DNA-binding transcription factor activity
A0J50_07505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A0J50_07510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A0J50_07515	COG0517	IMP dehydrogenase activity
A0J50_07515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A0J50_07540	COG0552	protein localization to endoplasmic reticulum
A0J50_07550	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A0J50_07565	COG4890	Cyd operon protein YbgT
A0J50_07570	COG1294	oxidase, subunit
A0J50_07585	COG1585	Membrane protein implicated in regulation of membrane protease activity
A0J50_07595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A0J50_07610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A0J50_07615	COG0569	domain protein
A0J50_07620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A0J50_07650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A0J50_07655	COG0542	response to heat
A0J50_07665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A0J50_07680	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0J50_07680	COG1902	pentaerythritol trinitrate reductase activity
A0J50_07720	COG0148	phosphopyruvate hydratase activity
A0J50_07725	COG2323	membrane
A0J50_07740	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A0J50_07750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A0J50_07755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A0J50_07760	COG0183	Belongs to the thiolase family
A0J50_07770	COG0596	Alpha beta hydrolase
A0J50_07775	COG2271	Major facilitator Superfamily
A0J50_07780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0J50_07785	COG3485	protocatechuate 3,4-dioxygenase
A0J50_07790	COG3485	protocatechuate 3,4-dioxygenase
A0J50_07795	COG0710	3-dehydroquinate dehydratase activity
A0J50_07800	COG3420	alginic acid biosynthetic process
A0J50_07805	COG3659	wide pore channel activity
A0J50_07810	COG4993	Dehydrogenase
A0J50_07835	COG1414	Transcriptional regulator
A0J50_07840	COG0583	DNA-binding transcription factor activity
A0J50_07870	COG2814	Major facilitator Superfamily
A0J50_07880	COG0154	amidase activity
A0J50_07900	COG4638	Rieske (2fe-2S)
A0J50_07910	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_07920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0J50_07930	COG3733	amine oxidase
A0J50_07940	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_07945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0J50_07950	COG0183	Belongs to the thiolase family
A0J50_07955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A0J50_07960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A0J50_07970	COG4829	muconolactone delta-isomerase
A0J50_07975	COG4948	Mandelate Racemase Muconate Lactonizing
A0J50_07980	COG0583	DNA-binding transcription factor activity
A0J50_07990	COG2186	Transcriptional regulator
A0J50_08010	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_08015	COG2351	hydroxyisourate hydrolase activity
A0J50_08020	COG2233	PERMEase
A0J50_08030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0J50_08035	COG2186	Transcriptional regulator
A0J50_08050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0J50_08060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0J50_08080	COG1902	pentaerythritol trinitrate reductase activity
A0J50_08080	COG0446	pyridine nucleotide-disulphide oxidoreductase
A0J50_08120	COG1309	transcriptional regulator
A0J50_08130	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_08140	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_08160	COG0318	PFAM AMP-dependent synthetase and ligase
A0J50_08180	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_08190	COG0583	DNA-binding transcription factor activity
A0J50_08215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A0J50_08220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A0J50_08270	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_08275	COG0129	dihydroxy-acid dehydratase activity
A0J50_08285	COG0583	DNA-binding transcription factor activity
A0J50_08290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A0J50_08300	COG2084	Dehydrogenase
A0J50_08320	COG1120	ATPase activity
A0J50_08340	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0J50_08430	COG2856	Zn peptidase
A0J50_08465	COG2207	Transcriptional regulator
A0J50_08540	COG1122	ATPase activity
A0J50_08570	COG0210	DNA helicase
A0J50_08580	COG1570	exodeoxyribonuclease VII activity
A0J50_08660	COG3539	Fimbrial protein
A0J50_08685	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A0J50_08695	COG0753	catalase activity
A0J50_08715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A0J50_08725	COG2205	protein histidine kinase activity
A0J50_08730	COG0745	RESPONSE REGULATOR receiver
A0J50_08735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_08785	COG1535	isochorismatase
A0J50_08785	COG3433	isochorismatase activity
A0J50_08790	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_08795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A0J50_08800	COG4149	molybdate abc transporter
A0J50_08805	COG0725	ABC transporter, periplasmic molybdate-binding protein
A0J50_08815	COG4638	Rieske (2fe-2S)
A0J50_08820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A0J50_08825	COG0543	2 iron, 2 sulfur cluster binding
A0J50_08825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0J50_08840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0J50_08850	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_08855	COG0412	Dienelactone hydrolase
A0J50_08865	COG2207	Transcriptional regulator
A0J50_08905	COG0583	DNA-binding transcription factor activity
A0J50_08920	COG2031	fatty acid transporter
A0J50_08925	COG0183	Belongs to the thiolase family
A0J50_08930	COG0583	DNA-binding transcription factor activity
A0J50_08935	COG0583	DNA-binding transcription factor activity
A0J50_08950	COG1027	Aspartate ammonia-lyase
A0J50_08960	COG0477	Major facilitator Superfamily
A0J50_08970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0J50_08975	COG1733	regulation of RNA biosynthetic process
A0J50_08980	COG2207	Transcriptional regulator
A0J50_08980	COG3708	Transcriptional regulator
A0J50_08995	COG0730	response to heat
A0J50_09015	COG3781	membrane
A0J50_09020	COG1063	alcohol dehydrogenase
A0J50_09030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A0J50_09040	COG0022	dehydrogenase e1 component
A0J50_09045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A0J50_09050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A0J50_09065	COG3706	GGDEF domain
A0J50_09085	COG0133	tryptophan synthase activity
A0J50_09095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A0J50_09120	COG0583	DNA-binding transcription factor activity
A0J50_09125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0J50_09135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A0J50_09195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A0J50_09200	COG4773	Receptor
A0J50_09220	COG0730	response to heat
A0J50_09225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A0J50_09245	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A0J50_09260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A0J50_09270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A0J50_09285	COG1960	acyl-CoA dehydrogenase activity
A0J50_09290	COG1960	acyl-CoA dehydrogenase activity
A0J50_09295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0J50_09300	COG2207	Transcriptional regulator
A0J50_09305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0J50_09310	COG0776	regulation of translation
A0J50_09335	COG0822	iron-sulfur transferase activity
A0J50_09340	COG0316	Belongs to the HesB IscA family
A0J50_09370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A0J50_09390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A0J50_09395	COG0702	epimerase
A0J50_09445	COG4166	transmembrane transport
A0J50_09485	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A0J50_09490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A0J50_09505	COG2431	L-lysine efflux transmembrane transporter activity
A0J50_09520	COG0776	regulation of translation
A0J50_09540	COG0590	tRNA wobble adenosine to inosine editing
A0J50_09585	COG0084	hydrolase, TatD family'
A0J50_09605	COG1663	tetraacyldisaccharide 4'-kinase activity
A0J50_09620	COG0811	peptide transport
A0J50_09625	COG1475	DNA binding
A0J50_09630	COG1192	Involved in chromosome partitioning
A0J50_09640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A0J50_09645	COG3178	'Phosphotransferase
A0J50_09655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A0J50_09680	COG0424	maF-like protein
A0J50_09685	COG2850	peptidyl-arginine hydroxylation
A0J50_09695	COG0640	Transcriptional regulator
A0J50_09705	COG3619	membrane
A0J50_09710	COG3122	Protein conserved in bacteria
A0J50_09715	COG1132	(ABC) transporter
A0J50_09735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A0J50_09740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A0J50_09750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A0J50_09750	COG0506	proline dehydrogenase activity
A0J50_09750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A0J50_09755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A0J50_09770	COG3698	Phosphodiester glycosidase
A0J50_09780	COG2353	YceI-like domain
A0J50_09790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A0J50_09860	COG3539	Fimbrial protein
A0J50_09900	COG0697	spore germination
A0J50_09910	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A0J50_09920	COG0583	DNA-binding transcription factor activity
A0J50_09935	COG1309	transcriptional regulator
A0J50_09950	COG1522	sequence-specific DNA binding
A0J50_09960	COG1126	abc transporter atp-binding protein
A0J50_09965	COG0765	amino acid transport
A0J50_09970	COG0765	amino acid transport
A0J50_10005	COG1464	Belongs to the NlpA lipoprotein family
A0J50_10015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A0J50_10020	COG2011	ABC-type metal ion transport system permease component
A0J50_10025	COG0012	GTP binding
A0J50_10050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A0J50_10085	COG1917	Cupin 2, conserved barrel domain protein
A0J50_10085	COG2207	Transcriptional regulator
A0J50_10090	COG0386	Belongs to the glutathione peroxidase family
A0J50_10100	COG0436	Aminotransferase
A0J50_10105	COG1301	dicarboxylic acid transport
A0J50_10145	COG3634	alkyl hydroperoxide reductase activity
A0J50_10160	COG0583	DNA-binding transcription factor activity
A0J50_10165	COG0431	NADPH-dependent FMN reductase
A0J50_10170	COG0798	PFAM Bile acid sodium symporter
A0J50_10200	COG0583	DNA-binding transcription factor activity
A0J50_10210	COG1953	Uracil, thiamine, allantoin
A0J50_10220	COG2175	clavaminate synthase activity
A0J50_10225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0J50_10230	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A0J50_10265	COG1271	oxidase subunit
A0J50_10270	COG1294	oxidase, subunit
A0J50_10275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_10295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A0J50_10315	COG3052	prosthetic group binding
A0J50_10320	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A0J50_10330	COG0583	DNA-binding transcription factor activity
A0J50_10335	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_10340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A0J50_10350	COG2814	Major facilitator Superfamily
A0J50_10355	COG0300	oxidoreductase activity
A0J50_10375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_10380	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_10390	COG1346	cytolysis
A0J50_10400	COG0583	DNA-binding transcription factor activity
A0J50_10410	COG0625	glutathione transferase activity
A0J50_10430	COG0583	DNA-binding transcription factor activity
A0J50_10435	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_10445	COG1045	serine acetyltransferase
A0J50_10450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A0J50_10455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A0J50_10460	COG1280	lysine exporter protein (LysE YggA)
A0J50_10470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0J50_10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A0J50_10485	COG0765	amino acid transport
A0J50_10490	COG0765	amino acid transport
A0J50_10505	COG0784	Response regulator, receiver
A0J50_10505	COG2205	protein histidine kinase activity
A0J50_10525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A0J50_10540	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_10550	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_10600	COG0583	DNA-binding transcription factor activity
A0J50_10610	COG2814	Major facilitator Superfamily
A0J50_10625	COG0318	PFAM AMP-dependent synthetase and ligase
A0J50_10630	COG1309	transcriptional regulator
A0J50_10635	COG1960	acyl-CoA dehydrogenase activity
A0J50_10640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A0J50_10645	COG1024	Enoyl-CoA hydratase
A0J50_10700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A0J50_10705	COG2814	Major facilitator Superfamily
A0J50_10710	COG1960	acyl-CoA dehydrogenase activity
A0J50_10720	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_10730	COG0183	Belongs to the thiolase family
A0J50_10740	COG2814	Major facilitator Superfamily
A0J50_10750	COG1024	Enoyl-CoA hydratase
A0J50_10770	COG2814	Major facilitator Superfamily
A0J50_10775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A0J50_10795	COG3842	ATPase activity
A0J50_10800	COG1840	ABC-type Fe3 transport system, periplasmic component
A0J50_10815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0J50_10820	COG1414	Transcriptional regulator
A0J50_10830	COG0583	DNA-binding transcription factor activity
A0J50_10855	COG2050	protein possibly involved in aromatic compounds catabolism
A0J50_10865	COG3327	negative regulation of DNA-templated transcription, initiation
A0J50_10870	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A0J50_10875	COG0183	Belongs to the thiolase family
A0J50_10880	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0J50_10885	COG1024	Enoyl-CoA hydratase
A0J50_10890	COG1024	Enoyl-CoA hydratase
A0J50_10895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0J50_10900	COG2151	metal-sulfur cluster biosynthetic enzyme
A0J50_10905	COG3396	Phenylacetate-CoA oxygenase
A0J50_10910	COG3460	Phenylacetate-CoA oxygenase
A0J50_10915	COG3396	Phenylacetate-CoA oxygenase
A0J50_10920	COG2030	dehydratase
A0J50_10920	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_10925	COG1760	l-serine dehydratase
A0J50_10940	COG0789	Transcriptional regulator
A0J50_10950	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A0J50_10955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_10970	COG2807	transmembrane transport
A0J50_10975	COG0590	tRNA wobble adenosine to inosine editing
A0J50_10985	COG0583	DNA-binding transcription factor activity
A0J50_10995	COG1063	alcohol dehydrogenase
A0J50_11000	COG1250	3-hydroxyacyl-CoA dehydrogenase
A0J50_11035	COG2831	hemolysin activation secretion protein
A0J50_11040	COG0038	chloride channel
A0J50_11045	COG4770	biotin carboxylase activity
A0J50_11065	COG1914	H( )-stimulated, divalent metal cation uptake system
A0J50_11070	COG0583	DNA-binding transcription factor activity
A0J50_11080	COG1595	DNA-templated transcription, initiation
A0J50_11090	COG3220	belongs to the UPF0276 family
A0J50_11145	COG0702	epimerase
A0J50_11150	COG1733	regulation of RNA biosynthetic process
A0J50_11165	COG1051	belongs to the nudix hydrolase family
A0J50_11175	COG1595	DNA-templated transcription, initiation
A0J50_11180	COG3712	iron ion homeostasis
A0J50_11215	COG3038	cytochrome b561
A0J50_11220	COG0753	catalase activity
A0J50_11225	COG1733	regulation of RNA biosynthetic process
A0J50_11240	COG1469	GTP cyclohydrolase I activity
A0J50_11250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A0J50_11265	COG1522	sequence-specific DNA binding
A0J50_11270	COG0531	amino acid
A0J50_11275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A0J50_11290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A0J50_11305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A0J50_11315	COG4122	O-methyltransferase activity
A0J50_11325	COG0110	maltose O-acetyltransferase activity
A0J50_11345	COG1538	Outer membrane efflux protein
A0J50_11350	COG1137	ATPase activity
A0J50_11355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A0J50_11365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A0J50_11405	COG1733	regulation of RNA biosynthetic process
A0J50_11410	COG2814	Major facilitator Superfamily
A0J50_11420	COG0668	transmembrane transport
A0J50_11460	COG1309	transcriptional regulator
A0J50_11485	COG2226	methyltransferase
A0J50_11505	COG1280	lysine exporter protein (LysE YggA)
A0J50_11540	COG1570	exodeoxyribonuclease VII activity
A0J50_11620	COG2871	sodium ion transport
A0J50_11630	COG0583	DNA-binding transcription factor activity
A0J50_11635	COG4638	Rieske (2fe-2S)
A0J50_11640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A0J50_11645	COG0633	Ferredoxin
A0J50_11645	COG0543	2 iron, 2 sulfur cluster binding
A0J50_11650	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_11655	COG3135	benzoate transporter
A0J50_11660	COG2814	Major facilitator Superfamily
A0J50_11680	COG0450	alkyl hydroperoxide reductase
A0J50_11700	COG3634	alkyl hydroperoxide reductase activity
A0J50_11720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A0J50_11730	COG0625	glutathione transferase activity
A0J50_11740	COG2885	chlorophyll binding
A0J50_11775	COG0542	response to heat
A0J50_11790	COG1765	OsmC-like protein
A0J50_11800	COG0667	Aldo Keto reductase
A0J50_11825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A0J50_11845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A0J50_11855	COG3038	cytochrome b561
A0J50_11865	COG2252	PERMEase
A0J50_11875	COG1741	Belongs to the pirin family
A0J50_11880	COG1309	transcriptional regulator
A0J50_11895	COG2072	flavoprotein involved in K transport
A0J50_11900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A0J50_11930	COG1944	ATP diphosphatase activity
A0J50_11950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A0J50_11965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A0J50_11980	COG2814	Major facilitator Superfamily
A0J50_11995	COG1113	amino acid transport
A0J50_12035	COG0531	amino acid
A0J50_12085	COG4269	membrane
A0J50_12115	COG5001	Diguanylate cyclase
A0J50_12115	COG4251	negative regulation of phosphorylation
A0J50_12115	COG3706	GGDEF domain
A0J50_12115	COG2203	Gaf domain
A0J50_12125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A0J50_12150	COG4172	Belongs to the ABC transporter superfamily
A0J50_12155	COG4239	(ABC) transporter, permease
A0J50_12160	COG4174	ABC transporter (Permease)
A0J50_12165	COG4166	transmembrane transport
A0J50_12170	COG0741	lytic transglycosylase activity
A0J50_12170	COG1388	LysM domain
A0J50_12175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A0J50_12210	COG0583	DNA-binding transcription factor activity
A0J50_12215	COG1279	arginine transmembrane transporter activity
A0J50_12225	COG0789	Transcriptional regulator
A0J50_12235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0J50_12240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0J50_12245	COG0006	proline dipeptidase activity
A0J50_12295	COG3384	dioxygenase
A0J50_12305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A0J50_12310	COG2878	Part of a membrane complex involved in electron transport
A0J50_12315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A0J50_12335	COG0768	penicillin binding
A0J50_12340	COG0742	ribosomal rna small subunit methyltransferase
A0J50_12355	COG0830	nickel cation binding
A0J50_12365	COG0804	urea catabolic process
A0J50_12395	COG3015	lipoprotein NlpE involved in copper resistance
A0J50_12410	COG1253	flavin adenine dinucleotide binding
A0J50_12415	COG2851	Citrate transporter
A0J50_12460	COG1773	rubredoxin
A0J50_12465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A0J50_12470	COG0596	Alpha beta hydrolase
A0J50_12475	COG0583	DNA-binding transcription factor activity
A0J50_12505	COG4181	ATPase activity
A0J50_12550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A0J50_12565	COG0306	phosphate transporter
A0J50_12595	COG3958	Transketolase
A0J50_12600	COG3959	Transketolase, thiamine diphosphate binding domain
A0J50_12605	COG2271	Major facilitator Superfamily
A0J50_12610	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_12615	COG0583	DNA-binding transcription factor activity
A0J50_12630	COG2223	nitrite transmembrane transporter activity
A0J50_12635	COG2207	Transcriptional regulator
A0J50_12640	COG2066	Belongs to the glutaminase family
A0J50_12645	COG0242	peptide deformylase activity
A0J50_12650	COG0477	Major facilitator Superfamily
A0J50_12660	COG0028	Belongs to the TPP enzyme family
A0J50_12675	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_12680	COG2267	carboxylic ester hydrolase activity
A0J50_12690	COG2271	Major facilitator Superfamily
A0J50_12705	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_12725	COG1414	Transcriptional regulator
A0J50_12740	COG1024	Enoyl-CoA hydratase
A0J50_12750	COG1215	transferase activity, transferring glycosyl groups
A0J50_12755	COG0726	polysaccharide deacetylase
A0J50_12755	COG1649	PFAM Uncharacterised BCR, COG1649
A0J50_12765	COG4681	YaeQ
A0J50_12785	COG1607	acyl-coa hydrolase
A0J50_12885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A0J50_12890	COG0477	Major facilitator Superfamily
A0J50_12930	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
A0J50_12970	COG0405	Gamma-glutamyltransferase
A0J50_12975	COG2814	Major facilitator Superfamily
A0J50_12985	COG2050	protein possibly involved in aromatic compounds catabolism
A0J50_13000	COG1090	epimerase
A0J50_13020	COG0420	3'-5' exonuclease activity
A0J50_13045	COG0735	belongs to the Fur family
A0J50_13050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A0J50_13055	COG2914	Belongs to the UPF0125 (RnfH) family
A0J50_13070	COG0121	glutamine amidotransferase
A0J50_13085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0J50_13095	COG0210	DNA helicase
A0J50_13100	COG2885	chlorophyll binding
A0J50_13105	COG0204	Acyl-transferase
A0J50_13120	COG2894	cell division
A0J50_13135	COG1280	lysine exporter protein (LysE YggA)
A0J50_13140	COG1674	ftsk spoiiie
A0J50_13145	COG0492	ferredoxin-NADP+ reductase activity
A0J50_13150	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A0J50_13160	COG0456	acetyltransferase
A0J50_13175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0J50_13180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A0J50_13190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A0J50_13215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A0J50_13215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A0J50_13235	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_13240	COG4638	Rieske (2fe-2S)
A0J50_13255	COG0473	3-isopropylmalate dehydrogenase activity
A0J50_13260	COG0583	DNA-binding transcription factor activity
A0J50_13280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A0J50_13330	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
A0J50_13360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A0J50_13390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A0J50_13400	COG0351	phosphomethylpyrimidine kinase
A0J50_13400	COG0352	thiamine-phosphate diphosphorylase activity
A0J50_13400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A0J50_13405	COG1652	LysM domain
A0J50_13415	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_13430	COG1399	metal-binding, possibly nucleic acid-binding protein
A0J50_13435	COG3101	peptidyl-lysine hydroxylation
A0J50_13440	COG0009	L-threonylcarbamoyladenylate synthase
A0J50_13445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A0J50_13450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A0J50_13465	COG4106	trans-aconitate 2-methyltransferase activity
A0J50_13480	COG0596	Alpha beta hydrolase
A0J50_13480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0J50_13480	COG2226	methyltransferase
A0J50_13490	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A0J50_13495	COG2223	nitrite transmembrane transporter activity
A0J50_13515	COG1196	nuclear chromosome segregation
A0J50_13525	COG0730	response to heat
A0J50_13540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A0J50_13600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A0J50_13605	COG0489	protein tyrosine kinase activity
A0J50_13650	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A0J50_13655	COG2081	HI0933 family
A0J50_13660	COG0668	transmembrane transport
A0J50_13680	COG0583	DNA-binding transcription factor activity
A0J50_13700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A0J50_13705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A0J50_13735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A0J50_13760	COG2199	diguanylate cyclase activity
A0J50_13770	COG2205	protein histidine kinase activity
A0J50_13775	COG0745	RESPONSE REGULATOR receiver
A0J50_13785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A0J50_13835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A0J50_13840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A0J50_13850	COG0583	DNA-binding transcription factor activity
A0J50_13895	COG0583	DNA-binding transcription factor activity
A0J50_13900	COG1053	succinate dehydrogenase
A0J50_13915	COG1309	transcriptional regulator
A0J50_13940	COG0583	DNA-binding transcription factor activity
A0J50_13945	COG1063	alcohol dehydrogenase
A0J50_13975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A0J50_13980	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A0J50_13985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0J50_14005	COG2132	Multicopper oxidase
A0J50_14015	COG0561	phosphatase activity
A0J50_14020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A0J50_14045	COG1214	PFAM Peptidase M22, glycoprotease
A0J50_14105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A0J50_14110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A0J50_14115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A0J50_14185	COG1846	Transcriptional regulator
A0J50_14190	COG1764	response to oxidative stress
A0J50_14230	COG0037	tRNA processing
A0J50_14240	COG0248	Ppx GppA phosphatase
A0J50_14265	COG0072	phenylalanine-tRNA ligase activity
A0J50_14280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A0J50_14285	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A0J50_14300	COG1238	metal cluster binding
A0J50_14305	COG0625	glutathione transferase activity
A0J50_14325	COG0318	PFAM AMP-dependent synthetase and ligase
A0J50_14330	COG3028	Belongs to the UPF0307 family
A0J50_14335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A0J50_14355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A0J50_14360	COG0617	tRNA 3'-terminal CCA addition
A0J50_14365	COG1555	photosystem II stabilization
A0J50_14370	COG3956	TIGRFAM MazG family protein
A0J50_14375	COG4221	oxidoreductase activity
A0J50_14380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A0J50_14395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A0J50_14400	COG5002	protein histidine kinase activity
A0J50_14400	COG0784	Response regulator, receiver
A0J50_14400	COG2205	protein histidine kinase activity
A0J50_14405	COG1024	Enoyl-CoA hydratase
A0J50_14410	COG2084	Dehydrogenase
A0J50_14415	COG3622	Belongs to the hyi family
A0J50_14435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A0J50_14440	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A0J50_14445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A0J50_14450	COG0697	spore germination
A0J50_14460	COG2814	Major facilitator Superfamily
A0J50_14485	COG2072	flavoprotein involved in K transport
A0J50_14490	COG0492	ferredoxin-NADP+ reductase activity
A0J50_14495	COG0431	NADPH-dependent FMN reductase
A0J50_14500	COG0798	PFAM Bile acid sodium symporter
A0J50_14510	COG0640	Transcriptional regulator
A0J50_14545	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A0J50_14570	COG2132	Multicopper oxidase
A0J50_14585	COG2205	protein histidine kinase activity
A0J50_14665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A0J50_14675	COG0583	DNA-binding transcription factor activity
A0J50_14680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A0J50_14690	COG0084	hydrolase, TatD family'
A0J50_14705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A0J50_14745	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_14755	COG2015	COG2015, Alkyl sulfatase and related hydrolases
A0J50_14760	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_14865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A0J50_14870	COG0440	acetolactate synthase activity
A0J50_14875	COG0028	Belongs to the TPP enzyme family
A0J50_14895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_14900	COG0577	efflux transmembrane transporter activity
A0J50_14900	COG1136	(ABC) transporter
A0J50_14920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A0J50_14925	COG1162	GTPase activity
A0J50_14935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A0J50_14955	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A0J50_14975	COG1426	Protein conserved in bacteria
A0J50_15010	COG0793	Belongs to the peptidase S41A family
A0J50_15025	COG2267	carboxylic ester hydrolase activity
A0J50_15035	COG1012	belongs to the aldehyde dehydrogenase family
A0J50_15040	COG3265	gluconokinase activity
A0J50_15050	COG0800	Aldolase
A0J50_15060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A0J50_15065	COG0280	phosphate acetyltransferase
A0J50_15065	COG0857	belongs to the CobB CobQ family
A0J50_15070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A0J50_15070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A0J50_15090	COG0740	serine-type endopeptidase activity
A0J50_15100	COG4774	siderophore transport
A0J50_15110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A0J50_15120	COG2813	Specifically methylates the guanine in position
A0J50_15120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A0J50_15220	COG0788	formyltetrahydrofolate deformylase activity
A0J50_15235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A0J50_15240	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A0J50_15250	COG4651	solute:proton antiporter activity
A0J50_15250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A0J50_15270	COG0724	RNA recognition motif
A0J50_15275	COG0210	DNA helicase
A0J50_15300	COG1733	regulation of RNA biosynthetic process
A0J50_15310	COG2900	Belongs to the SlyX family
A0J50_15325	COG1560	Kdo2-lipid A biosynthetic process
A0J50_15335	COG1301	dicarboxylic acid transport
A0J50_15390	COG0473	3-isopropylmalate dehydrogenase activity
A0J50_15415	COG0583	DNA-binding transcription factor activity
A0J50_15455	COG0583	DNA-binding transcription factor activity
A0J50_15465	COG0625	glutathione transferase activity
A0J50_15470	COG2378	regulation of single-species biofilm formation
A0J50_15475	COG0546	phosphoglycolate phosphatase activity
A0J50_15485	COG1530	ribonuclease E activity
A0J50_15515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A0J50_15525	COG0534	Mate efflux family protein
A0J50_15540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A0J50_15565	COG0493	'glutamate synthase
A0J50_15575	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A0J50_15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A0J50_15595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A0J50_15605	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A0J50_15605	COG0644	oxidoreductase
A0J50_15620	COG4535	Mg2 and Co2 transporter CorC
A0J50_15630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A0J50_15660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A0J50_15675	COG0789	Transcriptional regulator
A0J50_15680	COG0598	Magnesium transport protein CorA
A0J50_15685	COG1185	polyribonucleotide nucleotidyltransferase activity
A0J50_15700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A0J50_15705	COG1074	ATP-dependent DNA helicase activity
A0J50_15710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A0J50_15730	COG2226	methyltransferase
A0J50_15775	COG1006	Multisubunit Na H antiporter MnhC subunit
A0J50_15780	COG0651	ATP synthesis coupled electron transport
A0J50_15790	COG2212	antiporter activity
A0J50_15800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A0J50_15810	COG0195	Participates in both transcription termination and antitermination
A0J50_15860	COG0237	dephospho-CoA kinase activity
A0J50_15870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A0J50_15885	COG0497	DNA recombination
A0J50_15895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A0J50_15925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A0J50_15925	COG2169	Transcriptional regulator
A0J50_15930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A0J50_16010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A0J50_16025	COG0326	Molecular chaperone. Has ATPase activity
A0J50_16040	COG2056	Na+-H+ antiporter family
A0J50_16110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A0J50_16140	COG0546	phosphoglycolate phosphatase activity
A0J50_16170	COG2826	transposase and inactivated derivatives, IS30 family
A0J50_16195	COG0181	hydroxymethylbilane synthase activity
A0J50_16205	COG3275	phosphorelay sensor kinase activity
A0J50_16225	COG1538	Outer membrane efflux protein
A0J50_16230	COG0697	spore germination
A0J50_16255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A0J50_16260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A0J50_16265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A0J50_16270	COG0772	Belongs to the SEDS family
A0J50_16295	COG4974	Belongs to the 'phage' integrase family
A0J50_16300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A0J50_16310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A0J50_16320	COG2197	response regulator
A0J50_16335	COG0793	Belongs to the peptidase S41A family
A0J50_16340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A0J50_16345	COG0795	lipopolysaccharide-transporting ATPase activity
A0J50_16385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0J50_16385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A0J50_16395	COG0004	ammonium transporteR
A0J50_16400	COG0347	Belongs to the P(II) protein family
A0J50_16475	COG1538	Outer membrane efflux protein
A0J50_16485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_16490	COG1230	cation diffusion facilitator family transporter
A0J50_16510	COG0789	Transcriptional regulator
A0J50_16540	COG2814	Major facilitator Superfamily
A0J50_16580	COG0633	Ferredoxin
A0J50_16630	COG0431	NADPH-dependent FMN reductase
A0J50_16640	COG0235	Class ii aldolase
A0J50_16665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A0J50_16680	COG0318	PFAM AMP-dependent synthetase and ligase
A0J50_16695	COG2860	membrane
A0J50_16705	COG1253	flavin adenine dinucleotide binding
A0J50_16725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A0J50_16760	COG0655	NAD(P)H dehydrogenase (quinone) activity
A0J50_16805	COG1309	transcriptional regulator
A0J50_16840	COG0758	DNA mediated transformation
A0J50_16850	COG0697	spore germination
A0J50_16870	COG0386	Belongs to the glutathione peroxidase family
A0J50_16885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A0J50_16895	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A0J50_16935	COG1121	(ABC) transporter
A0J50_16940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A0J50_16945	COG1280	lysine exporter protein (LysE YggA)
A0J50_16950	COG2837	iron assimilation
A0J50_16955	COG0281	malic enzyme
A0J50_17005	COG4399	Belongs to the UPF0754 family
A0J50_17010	COG2259	Doxx family
A0J50_17015	COG0586	Pfam SNARE associated Golgi protein
A0J50_17030	COG1192	Involved in chromosome partitioning
A0J50_17040	COG0271	Belongs to the BolA IbaG family
A0J50_17080	COG3321	synthase
A0J50_17080	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A0J50_17080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A0J50_17080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A0J50_17100	COG2197	response regulator
A0J50_17110	COG3916	Acyl-homoserine-lactone synthase
A0J50_17115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A0J50_17125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A0J50_17130	COG1113	amino acid transport
A0J50_17135	COG0697	spore germination
A0J50_17140	COG0477	Major facilitator Superfamily
A0J50_17145	COG1024	Enoyl-CoA hydratase
A0J50_17150	COG1024	Enoyl-CoA hydratase
A0J50_17155	COG1960	acyl-CoA dehydrogenase activity
A0J50_17160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A0J50_17180	COG1113	amino acid transport
A0J50_17185	COG1113	amino acid transport
A0J50_17190	COG0251	oxidation-reduction process
A0J50_17230	COG0564	pseudouridine synthase activity
A0J50_17250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A0J50_17295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A0J50_17310	COG1802	Transcriptional regulator
A0J50_17315	COG1448	Aminotransferase
A0J50_17320	COG0277	FAD linked oxidase domain protein
A0J50_17330	COG2186	Transcriptional regulator
A0J50_17340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A0J50_17355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A0J50_17360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A0J50_17400	COG1091	dTDP-4-dehydrorhamnose reductase activity
A0J50_17415	COG2244	polysaccharide biosynthetic process
A0J50_17430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A0J50_17460	COG0728	peptidoglycan biosynthetic process
A0J50_17465	COG3023	N-Acetylmuramoyl-L-alanine amidase
A0J50_17515	COG0546	phosphoglycolate phosphatase activity
A0J50_17520	COG1028	Short-chain dehydrogenase reductase Sdr
A0J50_17535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A0J50_17535	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A0J50_17540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0J50_17545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A0J50_17550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A0J50_17555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A0J50_17560	COG1116	anion transmembrane transporter activity
A0J50_17565	COG1309	transcriptional regulator
A0J50_17570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A0J50_17580	COG0196	riboflavin kinase activity
A0J50_17585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A0J50_17595	COG1047	Peptidyl-prolyl cis-trans
A0J50_17635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A0J50_17660	COG0583	DNA-binding transcription factor activity
A0J50_17695	COG2951	lytic endotransglycosylase activity
A0J50_17700	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A0J50_17715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A0J50_17725	COG0671	phosphoesterase, PA-phosphatase related
A0J50_17730	COG0861	Integral membrane protein TerC family
A0J50_17740	COG0754	glutathionylspermidine amidase activity
A0J50_17750	COG0402	S-adenosylhomocysteine deaminase activity
A0J50_17765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A0J50_17785	COG0706	membrane insertase activity
A0J50_17800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A0J50_17810	COG0592	DNA-directed DNA polymerase activity
A0J50_17820	COG0187	DNA topoisomerase II activity
A0J50_17835	COG0488	(ABC) transporter
A0J50_17860	COG0596	Alpha beta hydrolase
A0J50_17865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A0J50_17870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A0J50_17900	COG0625	glutathione transferase activity
A0J50_17910	COG0733	neurotransmitter:sodium symporter activity
A0J50_17945	COG2233	PERMEase
A0J50_17960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A0J50_18055	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
A0J50_18095	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
A0J50_18125	COG4221	oxidoreductase activity
A0J50_18130	COG0583	DNA-binding transcription factor activity
A0J50_18135	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A0J50_18140	COG0604	alcohol dehydrogenase
A0J50_18140	COG3321	synthase
A0J50_18155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0J50_18165	COG1979	alcohol dehydrogenase
A0J50_18175	COG1902	pentaerythritol trinitrate reductase activity
A0J50_18185	COG1309	transcriptional regulator
A0J50_18190	COG2130	NADP-dependent
A0J50_18205	COG0582	viral genome integration into host DNA
A0J50_18235	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
A0J50_18250	COG3316	Transposase and inactivated derivatives
A0J50_18255	COG0789	Transcriptional regulator
A0J50_18310	COG2351	hydroxyisourate hydrolase activity
A0J50_18315	COG2233	PERMEase
A0J50_18330	COG4266	Belongs to the allantoicase family
A0J50_18335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A0J50_18340	COG0583	DNA-binding transcription factor activity
A0J50_18350	COG2233	PERMEase
A0J50_18355	COG3248	Nucleoside-binding outer membrane protein
A0J50_18370	COG0583	DNA-binding transcription factor activity
A0J50_18440	COG3316	Transposase and inactivated derivatives
A0J50_18455	COG2207	Transcriptional regulator
A0J50_18460	COG0633	Ferredoxin
A0J50_18490	COG1309	transcriptional regulator
A0J50_18545	COG2184	nucleotidyltransferase activity
A0J50_18625	COG1373	ATPase (AAA superfamily
A0J50_18685	COG3316	Transposase and inactivated derivatives
A0J50_18800	COG1785	Belongs to the alkaline phosphatase family
A0J50_18805	COG1475	DNA binding
A0J50_18810	COG1192	Involved in chromosome partitioning
A0J50_18835	COG0604	alcohol dehydrogenase
A0J50_18860	COG0582	viral genome integration into host DNA
A0J50_18875	COG2130	NADP-dependent
A0J50_18880	COG1309	transcriptional regulator
A0J50_18890	COG1902	pentaerythritol trinitrate reductase activity
A0J50_18900	COG1979	alcohol dehydrogenase
A0J50_18910	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A0J50_18935	COG0477	Major facilitator Superfamily
A0J50_18940	COG0697	spore germination
A0J50_18945	COG0604	alcohol dehydrogenase
A0J50_18945	COG3321	synthase
A0J50_18950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A0J50_18955	COG0583	DNA-binding transcription factor activity
A0J50_18960	COG4221	oxidoreductase activity
A0J50_19030	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
A0J50_19070	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
A0J50_19130	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
A0J50_19160	COG0659	secondary active sulfate transmembrane transporter activity
A0J50_19165	COG0589	response to stress