locus-tag	class	description
EG365_00005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG365_00015	COG0303	'Molybdopterin
EG365_00020	COG0315	cyclic pyranopterin monophosphate synthase activity
EG365_00020	COG0521	Mo-molybdopterin cofactor biosynthetic process
EG365_00035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EG365_00040	COG0243	molybdopterin cofactor binding
EG365_00050	COG0243	molybdopterin cofactor binding
EG365_00055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EG365_00060	COG2146	nitrite reductase [NAD(P)H] activity
EG365_00060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EG365_00070	COG0745	RESPONSE REGULATOR receiver
EG365_00075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EG365_00075	COG1116	anion transmembrane transporter activity
EG365_00095	COG0511	ligase activity, forming carbon-carbon bonds
EG365_00110	COG2814	Major facilitator Superfamily
EG365_00465	COG0069	glutamate synthase activity
EG365_00485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EG365_00495	COG1454	alcohol dehydrogenase
EG365_00500	COG0824	Thioesterase
EG365_00510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EG365_00540	COG0183	Belongs to the thiolase family
EG365_00550	COG0583	DNA-binding transcription factor activity
EG365_00565	COG1522	sequence-specific DNA binding
EG365_00570	COG3135	benzoate transporter
EG365_00580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EG365_00595	COG0589	response to stress
EG365_00600	COG0488	(ABC) transporter
EG365_00620	COG4773	Receptor
EG365_00650	COG0668	transmembrane transport
EG365_00660	COG1309	transcriptional regulator
EG365_00680	COG1605	Chorismate mutase
EG365_00690	COG4221	oxidoreductase activity
EG365_00700	COG0308	aminopeptidase N
EG365_00720	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EG365_00730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EG365_00735	COG1454	alcohol dehydrogenase
EG365_00755	COG0531	amino acid
EG365_00760	COG4303	Ethanolamine ammonia lyase large subunit
EG365_00765	COG4302	ethanolamine ammonia-lyase activity
EG365_00770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EG365_00770	COG0519	Catalyzes the synthesis of GMP from XMP
EG365_00785	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG365_00800	COG0697	spore germination
EG365_00805	COG1923	regulation of RNA biosynthetic process
EG365_00815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EG365_00820	COG0802	atpase or kinase
EG365_00840	COG1187	pseudouridine synthase activity
EG365_00855	COG0583	DNA-binding transcription factor activity
EG365_00870	COG2814	Major facilitator Superfamily
EG365_00875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG365_00905	COG0729	surface antigen
EG365_00925	COG0174	glutamine synthetase
EG365_00930	COG0745	RESPONSE REGULATOR receiver
EG365_00935	COG2205	protein histidine kinase activity
EG365_00945	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EG365_00950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EG365_00975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG365_00980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EG365_00985	COG1960	acyl-CoA dehydrogenase activity
EG365_01000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EG365_01005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EG365_01025	COG0583	DNA-binding transcription factor activity
EG365_01045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG365_01055	COG3658	cytochrome
EG365_01060	COG1215	transferase activity, transferring glycosyl groups
EG365_01065	COG1649	PFAM Uncharacterised BCR, COG1649
EG365_01065	COG0726	polysaccharide deacetylase
EG365_01090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EG365_01095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EG365_01105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EG365_01130	COG0305	Participates in initiation and elongation during chromosome replication
EG365_01135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EG365_01145	COG1305	Transglutaminase-like
EG365_01155	COG2308	Evidence 4 Homologs of previously reported genes of
EG365_01185	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EG365_01190	COG0138	bifunctional purine biosynthesis protein purh
EG365_01195	COG0151	Belongs to the GarS family
EG365_01200	COG1464	Belongs to the NlpA lipoprotein family
EG365_01205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EG365_01210	COG2011	ABC-type metal ion transport system permease component
EG365_01215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG365_01225	COG1301	dicarboxylic acid transport
EG365_01255	COG1794	racemase activity, acting on amino acids and derivatives
EG365_01265	COG3008	intermembrane lipid transfer
EG365_01265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EG365_01270	COG2995	paraquat-inducible protein a
EG365_01280	COG2985	domain, Protein
EG365_01310	COG0477	Major facilitator Superfamily
EG365_01360	COG2186	Transcriptional regulator
EG365_01370	COG0786	glutamate:sodium symporter activity
EG365_01375	COG3243	poly(R)-hydroxyalkanoic acid synthase
EG365_01400	COG3111	PFAM Bacterial OB fold (BOF) protein
EG365_01495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EG365_01500	COG1610	YqeY-like protein
EG365_01505	COG4783	chaperone-mediated protein folding
EG365_01530	COG1286	toxin biosynthetic process
EG365_01560	COG0778	Nitroreductase
EG365_01570	COG0513	Belongs to the DEAD box helicase family
EG365_01590	COG2363	Small membrane protein
EG365_01620	COG1234	tRNA 3'-trailer cleavage
EG365_01625	COG2195	Cleaves the N-terminal amino acid of tripeptides
EG365_01635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EG365_01645	COG2819	hydrolase of the alpha beta superfamily
EG365_01650	COG1960	acyl-CoA dehydrogenase activity
EG365_01655	COG1301	dicarboxylic acid transport
EG365_01665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EG365_01670	COG3139	Protein of unknown function (DUF1315)
EG365_01675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EG365_01680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EG365_01690	COG0494	nUDIX hydrolase
EG365_01700	COG0642	Histidine kinase
EG365_01705	COG0745	RESPONSE REGULATOR receiver
EG365_01725	COG1720	tRNA m6t6A37 methyltransferase activity
EG365_01740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG365_01750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EG365_01760	COG4598	ABC transporter
EG365_01765	COG4160	amino acid transport
EG365_01770	COG4215	(ABC) transporter
EG365_01785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG365_01795	COG1538	Outer membrane efflux protein
EG365_01830	COG1131	(ABC) transporter
EG365_01835	COG0842	Transport permease protein
EG365_01850	COG0772	Belongs to the SEDS family
EG365_01855	COG2951	lytic endotransglycosylase activity
EG365_01880	COG2207	Transcriptional regulator
EG365_01895	COG0052	Belongs to the universal ribosomal protein uS2 family
EG365_01900	COG0024	Methionine aminopeptidase
EG365_01910	COG2223	nitrite transmembrane transporter activity
EG365_01920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG365_01925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EG365_01930	COG1960	acyl-CoA dehydrogenase activity
EG365_01945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EG365_01950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EG365_01955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EG365_01975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG365_01980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EG365_01985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EG365_02020	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EG365_02035	COG3104	oligopeptide transport
EG365_02045	COG0582	viral genome integration into host DNA
EG365_02140	COG1598	PFAM Uncharacterised protein family UPF0150
EG365_02420	COG0512	Glutamine amidotransferase of anthranilate synthase
EG365_02425	COG0308	aminopeptidase N
EG365_02455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EG365_02490	COG3739	integral membrane protein
EG365_02505	COG1169	isochorismate synthase
EG365_02515	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EG365_02525	COG1132	(ABC) transporter
EG365_02540	COG3433	isochorismatase activity
EG365_02540	COG1535	isochorismatase
EG365_02545	COG1021	2,3-dihydroxybenzoate-AMP ligase
EG365_02550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG365_02560	COG4774	siderophore transport
EG365_02565	COG4607	ABC-type enterochelin transport system periplasmic component
EG365_02570	COG4604	ABC transporter, ATP-binding protein
EG365_02575	COG4605	iron ion homeostasis
EG365_02580	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EG365_02585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG365_02635	COG0776	regulation of translation
EG365_02665	COG3267	Type II secretory pathway component ExeA
EG365_02665	COG3409	Peptidoglycan-binding domain 1 protein
EG365_02690	COG0681	Belongs to the peptidase S26 family
EG365_02725	COG4373	Mu-like prophage FluMu protein gp28
EG365_02740	COG4383	Mu-like prophage protein gp29
EG365_02745	COG2369	cell adhesion
EG365_02860	COG2964	Protein conserved in bacteria
EG365_02870	COG1741	Belongs to the pirin family
EG365_02890	COG1309	transcriptional regulator
EG365_02900	COG4948	Mandelate Racemase Muconate Lactonizing
EG365_02905	COG2814	Major facilitator Superfamily
EG365_02940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG365_02940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EG365_02945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EG365_02960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EG365_02965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EG365_02970	COG0583	DNA-binding transcription factor activity
EG365_02975	COG1113	amino acid transport
EG365_02995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EG365_02995	COG2508	Transcriptional regulator
EG365_03030	COG2879	small protein
EG365_03035	COG1966	Carbon starvation protein
EG365_03080	COG1067	ATP-dependent peptidase activity
EG365_03085	COG0583	DNA-binding transcription factor activity
EG365_03110	COG1686	Belongs to the peptidase S11 family
EG365_03115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EG365_03150	COG0616	signal peptide processing
EG365_03155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EG365_03165	COG0573	inorganic phosphate transmembrane transporter activity
EG365_03170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EG365_03175	COG1113	amino acid transport
EG365_03180	COG3961	Belongs to the TPP enzyme family
EG365_03185	COG1522	sequence-specific DNA binding
EG365_03195	COG0076	glutamate decarboxylase activity
EG365_03200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EG365_03210	COG1309	transcriptional regulator
EG365_03225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG365_03260	COG0352	thiamine-phosphate diphosphorylase activity
EG365_03285	COG0612	Peptidase, M16
EG365_03300	COG0583	DNA-binding transcription factor activity
EG365_03305	COG0477	Major facilitator Superfamily
EG365_03330	COG1187	pseudouridine synthase activity
EG365_03345	COG1686	Belongs to the peptidase S11 family
EG365_03350	COG1252	NADH dehydrogenase
EG365_03360	COG0415	Belongs to the DNA photolyase family
EG365_03375	COG1215	transferase activity, transferring glycosyl groups
EG365_03405	COG2070	2-Nitropropane dioxygenase
EG365_03460	COG0556	nucleotide-excision repair
EG365_03510	COG4221	oxidoreductase activity
EG365_03520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EG365_03525	COG1381	Involved in DNA repair and RecF pathway recombination
EG365_03535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EG365_03550	COG0681	Belongs to the peptidase S26 family
EG365_03565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EG365_03585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EG365_03590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EG365_03595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EG365_03605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EG365_03610	COG4208	sulfate ABC transporter
EG365_03615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EG365_03620	COG0583	DNA-binding transcription factor activity
EG365_03625	COG4625	pathogenesis
EG365_03640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EG365_03655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EG365_03665	COG1051	belongs to the nudix hydrolase family
EG365_03665	COG1056	cytidyltransferase-related domain
EG365_03670	COG1024	Enoyl-CoA hydratase
EG365_03675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EG365_03680	COG2814	Major facilitator Superfamily
EG365_03685	COG0047	phosphoribosylformylglycinamidine synthase activity
EG365_03685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EG365_03705	COG1473	amidohydrolase
EG365_03710	COG0824	Thioesterase
EG365_03730	COG0823	Involved in the tonB-independent uptake of proteins
EG365_03750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG365_03785	COG0628	permease
EG365_03795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EG365_03800	COG0596	Alpha beta hydrolase
EG365_03805	COG0616	signal peptide processing
EG365_03805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EG365_03815	COG2333	competence protein COMEC
EG365_03815	COG0658	competence protein
EG365_03820	COG1136	(ABC) transporter
EG365_03825	COG4591	ABC-type transport system involved in lipoprotein release permease component
EG365_03855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG365_03875	COG0463	Glycosyl transferase, family 2
EG365_03905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EG365_03910	COG1280	lysine exporter protein (LysE YggA)
EG365_03920	COG0019	diaminopimelate decarboxylase activity
EG365_03930	COG1113	amino acid transport
EG365_03945	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EG365_03955	COG3339	Conserved Protein
EG365_03960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EG365_03965	COG0243	molybdopterin cofactor binding
EG365_03970	COG1929	Belongs to the glycerate kinase type-1 family
EG365_03985	COG0778	Nitroreductase
EG365_04010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG365_04025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EG365_04050	COG0741	lytic transglycosylase activity
EG365_04070	COG0584	glycerophosphoryl diester phosphodiesterase
EG365_04075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG365_04100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EG365_04120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EG365_04125	COG0477	Major facilitator Superfamily
EG365_04175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EG365_04180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG365_04205	COG0505	Belongs to the CarA family
EG365_04225	COG0589	response to stress
EG365_04240	COG2843	Capsule synthesis protein
EG365_04260	COG2321	neutral zinc metallopeptidase
EG365_04265	COG2354	Protein conserved in bacteria
EG365_04285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG365_04310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EG365_04315	COG1053	succinate dehydrogenase
EG365_04320	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EG365_04325	COG2009	succinate dehydrogenase
EG365_04365	COG2921	Belongs to the UPF0250 family
EG365_04370	COG0321	lipoyl(octanoyl) transferase activity
EG365_04385	COG0531	amino acid
EG365_04395	COG1733	regulation of RNA biosynthetic process
EG365_04400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EG365_04405	COG1648	precorrin-2 dehydrogenase activity
EG365_04405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EG365_04420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EG365_04450	COG0671	phosphoesterase, PA-phosphatase related
EG365_04455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG365_04465	COG1538	Outer membrane efflux protein
EG365_04470	COG0393	Putative heavy-metal-binding
EG365_04475	COG0393	Putative heavy-metal-binding
EG365_04485	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_04495	COG0525	valine-tRNA ligase activity
EG365_04515	COG0583	DNA-binding transcription factor activity
EG365_04525	COG0004	ammonium transporteR
EG365_04535	COG0642	Histidine kinase
EG365_04540	COG0745	RESPONSE REGULATOR receiver
EG365_04545	COG2194	sulfuric ester hydrolase activity
EG365_04565	COG1752	Esterase of the alpha-beta hydrolase superfamily
EG365_04580	COG2315	Protein conserved in bacteria
EG365_04585	COG0142	geranyltranstransferase activity
EG365_04590	COG2828	Protein conserved in bacteria
EG365_04595	COG1113	amino acid transport
EG365_04615	COG2207	Transcriptional regulator
EG365_04640	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG365_04660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EG365_04670	COG1530	ribonuclease E activity
EG365_04675	COG0424	maF-like protein
EG365_04680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EG365_04685	COG1792	Involved in formation and maintenance of cell shape
EG365_04690	COG1077	Cell shape determining protein MreB Mrl
EG365_04695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EG365_04705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EG365_04735	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EG365_04740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EG365_04745	COG1752	Esterase of the alpha-beta hydrolase superfamily
EG365_04750	COG1115	amino acid carrier protein
EG365_04770	COG2814	Major facilitator Superfamily
EG365_04775	COG1289	transmembrane transporter activity
EG365_04825	COG1376	ErfK ybiS ycfS ynhG family protein
EG365_04830	COG2832	Protein of unknown function (DUF454)
EG365_04840	COG5510	response to toxic substance
EG365_04860	COG0840	transmembrane signaling receptor activity
EG365_04900	COG3422	double-strand break repair
EG365_04905	COG2824	Alkylphosphonate utilization operon protein PhnA
EG365_04910	COG3189	MarR family transcriptional regulator
EG365_04920	COG0354	folic acid binding
EG365_04925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EG365_04940	COG1902	pentaerythritol trinitrate reductase activity
EG365_04945	COG4772	TonB-dependent receptor
EG365_04950	COG2094	Belongs to the DNA glycosylase MPG family
EG365_04980	COG2233	PERMEase
EG365_04990	COG0833	amino acid
EG365_04995	COG1690	Belongs to the RtcB family
EG365_05005	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EG365_05005	COG2885	chlorophyll binding
EG365_05015	COG0183	Belongs to the thiolase family
EG365_05035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EG365_05055	COG2207	Transcriptional regulator
EG365_05060	COG0183	Belongs to the thiolase family
EG365_05090	COG1272	protein, Hemolysin III
EG365_05095	COG0477	Major facilitator Superfamily
EG365_05110	COG0450	alkyl hydroperoxide reductase
EG365_05130	COG0285	dihydrofolate synthase activity
EG365_05165	COG0133	tryptophan synthase activity
EG365_05180	COG2096	Adenosyltransferase
EG365_05200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EG365_05205	COG0745	RESPONSE REGULATOR receiver
EG365_05210	COG2205	protein histidine kinase activity
EG365_05220	COG1960	acyl-CoA dehydrogenase activity
EG365_05225	COG1960	acyl-CoA dehydrogenase activity
EG365_05230	COG0583	DNA-binding transcription factor activity
EG365_05235	COG0625	glutathione transferase activity
EG365_05300	COG0438	transferase activity, transferring glycosyl groups
EG365_05305	COG0463	Glycosyl transferase, family 2
EG365_05310	COG0726	polysaccharide deacetylase
EG365_05330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EG365_05335	COG2205	protein histidine kinase activity
EG365_05385	COG1862	Preprotein translocase
EG365_05395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EG365_05400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EG365_05410	COG3781	membrane
EG365_05415	COG0613	PHP domain protein
EG365_05425	COG2350	Protein conserved in bacteria
EG365_05455	COG1607	acyl-coa hydrolase
EG365_05470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG365_05470	COG3453	Protein conserved in bacteria
EG365_05525	COG2199	diguanylate cyclase activity
EG365_05535	COG1408	metallophosphoesterase
EG365_05540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EG365_05550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EG365_05570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EG365_05575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EG365_05590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EG365_05600	COG2969	positive regulation of protein catabolic process
EG365_05620	COG1960	acyl-CoA dehydrogenase activity
EG365_05625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EG365_05640	COG1309	transcriptional regulator
EG365_05645	COG1960	acyl-CoA dehydrogenase activity
EG365_05690	COG1183	phosphatidylcholine synthase activity
EG365_05695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EG365_05725	COG1196	nuclear chromosome segregation
EG365_05725	COG0741	lytic transglycosylase activity
EG365_05725	COG0739	heme binding
EG365_05735	COG1702	phosphate starvation-inducible protein PhoH
EG365_05770	COG1295	ribonuclease BN
EG365_05775	COG0697	spore germination
EG365_05780	COG2169	Transcriptional regulator
EG365_05785	COG0179	Fumarylacetoacetate (FAA) hydrolase
EG365_05830	COG0557	exoribonuclease II activity
EG365_05835	COG0339	signal peptide processing
EG365_05840	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EG365_05870	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EG365_05875	COG1960	acyl-CoA dehydrogenase activity
EG365_05900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EG365_05910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EG365_06030	COG0626	cystathionine gamma-synthase activity
EG365_06035	COG0433	COG0433 Predicted ATPase
EG365_06040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG365_06040	COG1017	nitric oxide dioxygenase activity
EG365_06045	COG1959	2 iron, 2 sulfur cluster binding
EG365_06060	COG1301	dicarboxylic acid transport
EG365_06065	COG1946	Acyl-CoA thioesterase
EG365_06085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EG365_06090	COG1040	competence protein
EG365_06095	COG0494	nUDIX hydrolase
EG365_06105	COG0598	Magnesium transport protein CorA
EG365_06115	COG2854	intermembrane phospholipid transfer
EG365_06125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EG365_06130	COG1127	ABC transporter
EG365_06135	COG0513	Belongs to the DEAD box helicase family
EG365_06155	COG0408	coproporphyrinogen oxidase activity
EG365_06170	COG1960	acyl-CoA dehydrogenase activity
EG365_06180	COG1983	PspC domain protein
EG365_06185	COG0517	IMP dehydrogenase activity
EG365_06230	COG0583	DNA-binding transcription factor activity
EG365_06270	COG1012	belongs to the aldehyde dehydrogenase family
EG365_06280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EG365_06285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EG365_06290	COG0833	amino acid
EG365_06320	COG1192	Involved in chromosome partitioning
EG365_06325	COG0628	permease
EG365_06335	COG1289	transmembrane transporter activity
EG365_06350	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG365_06355	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EG365_06365	COG0277	FAD linked oxidase domain protein
EG365_06370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EG365_06395	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EG365_06400	COG5380	lipid catabolic process
EG365_06420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EG365_06470	COG0194	GDP metabolic process
EG365_06485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EG365_06505	COG3307	-O-antigen
EG365_06525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EG365_06530	COG1704	LemA family
EG365_06540	COG0493	'glutamate synthase
EG365_06545	COG0069	glutamate synthase activity
EG365_06545	COG0070	glutamate synthase
EG365_06545	COG0067	glutamate synthase
EG365_06595	COG2226	methyltransferase
EG365_06610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EG365_06615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EG365_06660	COG0833	amino acid
EG365_06725	COG0488	(ABC) transporter
EG365_06735	COG4221	oxidoreductase activity
EG365_06740	COG0659	secondary active sulfate transmembrane transporter activity
EG365_06750	COG0745	RESPONSE REGULATOR receiver
EG365_06765	COG0427	acetyl-CoA hydrolase
EG365_06795	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EG365_06835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EG365_06890	COG2207	Transcriptional regulator
EG365_06895	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EG365_06920	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG365_06930	COG1733	regulation of RNA biosynthetic process
EG365_06945	COG1733	regulation of RNA biosynthetic process
EG365_06970	COG0667	Aldo Keto reductase
EG365_06995	COG0583	DNA-binding transcription factor activity
EG365_07000	COG2814	Major facilitator Superfamily
EG365_07030	COG1335	isochorismatase
EG365_07040	COG1012	belongs to the aldehyde dehydrogenase family
EG365_07045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EG365_07055	COG1113	amino acid transport
EG365_07065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EG365_07080	COG2814	Major facilitator Superfamily
EG365_07090	COG0352	thiamine-phosphate diphosphorylase activity
EG365_07090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EG365_07090	COG0351	phosphomethylpyrimidine kinase
EG365_07110	COG1309	transcriptional regulator
EG365_07115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EG365_07120	COG3706	GGDEF domain
EG365_07130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EG365_07140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG365_07145	COG3162	membrane
EG365_07150	COG0784	Response regulator, receiver
EG365_07150	COG2198	Histidine kinase
EG365_07150	COG2205	protein histidine kinase activity
EG365_07175	COG1522	sequence-specific DNA binding
EG365_07180	COG1335	isochorismatase
EG365_07185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EG365_07195	COG0668	transmembrane transport
EG365_07200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EG365_07205	COG1519	Transferase
EG365_07210	COG1902	pentaerythritol trinitrate reductase activity
EG365_07230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EG365_07255	COG0426	domain, Protein
EG365_07255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG365_07260	COG4774	siderophore transport
EG365_07265	COG2119	membrane
EG365_07275	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG365_07285	COG4942	peptidase
EG365_07300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EG365_07310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EG365_07330	COG0189	ligase activity
EG365_07350	COG0708	Exodeoxyribonuclease III
EG365_07355	COG1393	Belongs to the ArsC family
EG365_07410	COG2233	PERMEase
EG365_07420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG365_07430	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EG365_07440	COG3150	esterase
EG365_07465	COG3179	chitinase
EG365_07470	COG3501	Rhs element vgr protein
EG365_07480	COG2918	glutathione biosynthetic process
EG365_07495	COG2733	membrane
EG365_07500	COG0436	Aminotransferase
EG365_07505	COG0534	Mate efflux family protein
EG365_07565	COG0753	catalase activity
EG365_07615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EG365_07620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EG365_07630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EG365_07635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EG365_07640	COG0546	phosphoglycolate phosphatase activity
EG365_07650	COG0010	Belongs to the arginase family
EG365_07680	COG2188	Transcriptional regulator
EG365_07690	COG0523	cobalamin synthesis protein
EG365_07700	COG1113	amino acid transport
EG365_07710	COG0625	glutathione transferase activity
EG365_07730	COG1683	Conserved Protein
EG365_07735	COG0534	Mate efflux family protein
EG365_07740	COG0385	Bile acid
EG365_07745	COG1335	isochorismatase
EG365_07750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG365_07775	COG2116	formate transmembrane transporter activity
EG365_07780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EG365_07785	COG2133	pyrroloquinoline quinone binding
EG365_07790	COG2983	Belongs to the UPF0260 family
EG365_07810	COG1194	a g-specific adenine glycosylase
EG365_07825	COG2818	Glycosylase
EG365_07830	COG1064	alcohol dehydrogenase
EG365_07835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG365_07850	COG0583	DNA-binding transcription factor activity
EG365_07855	COG0656	L-ascorbic acid biosynthetic process
EG365_07860	COG2814	Major facilitator Superfamily
EG365_07895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG365_07910	COG2233	PERMEase
EG365_07950	COG0733	neurotransmitter:sodium symporter activity
EG365_07995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EG365_08000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EG365_08005	COG0596	Alpha beta hydrolase
EG365_08030	COG0488	(ABC) transporter
EG365_08035	COG0586	Pfam SNARE associated Golgi protein
EG365_08045	COG0187	DNA topoisomerase II activity
EG365_08055	COG0592	DNA-directed DNA polymerase activity
EG365_08065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EG365_08080	COG0706	membrane insertase activity
EG365_08095	COG1230	cation diffusion facilitator family transporter
EG365_08100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EG365_08115	COG0402	S-adenosylhomocysteine deaminase activity
EG365_08125	COG0754	glutathionylspermidine amidase activity
EG365_08140	COG0861	Integral membrane protein TerC family
EG365_08145	COG0671	phosphoesterase, PA-phosphatase related
EG365_08155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EG365_08175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EG365_08180	COG2951	lytic endotransglycosylase activity
EG365_08240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EG365_08280	COG1047	Peptidyl-prolyl cis-trans
EG365_08290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EG365_08295	COG0196	riboflavin kinase activity
EG365_08305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EG365_08310	COG1309	transcriptional regulator
EG365_08315	COG1116	anion transmembrane transporter activity
EG365_08320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EG365_08325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG365_08330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EG365_08335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EG365_08355	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_08360	COG0546	phosphoglycolate phosphatase activity
EG365_08415	COG3023	N-Acetylmuramoyl-L-alanine amidase
EG365_08420	COG0728	peptidoglycan biosynthetic process
EG365_08445	COG1596	polysaccharide export
EG365_08450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EG365_08480	COG0438	transferase activity, transferring glycosyl groups
EG365_08505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EG365_08510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EG365_08525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EG365_08530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EG365_08540	COG2186	Transcriptional regulator
EG365_08550	COG0277	FAD linked oxidase domain protein
EG365_08555	COG1448	Aminotransferase
EG365_08565	COG1802	Transcriptional regulator
EG365_08580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EG365_08600	COG1051	belongs to the nudix hydrolase family
EG365_08630	COG0564	pseudouridine synthase activity
EG365_08655	COG1522	sequence-specific DNA binding
EG365_08670	COG0251	oxidation-reduction process
EG365_08675	COG1113	amino acid transport
EG365_08680	COG1113	amino acid transport
EG365_08700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EG365_08705	COG1960	acyl-CoA dehydrogenase activity
EG365_08710	COG1024	Enoyl-CoA hydratase
EG365_08715	COG1024	Enoyl-CoA hydratase
EG365_08720	COG0477	Major facilitator Superfamily
EG365_08725	COG3916	Acyl-homoserine-lactone synthase
EG365_08735	COG2197	response regulator
EG365_08745	COG1960	acyl-CoA dehydrogenase activity
EG365_08750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EG365_08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG365_08750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EG365_08750	COG3321	synthase
EG365_08770	COG2267	carboxylic ester hydrolase activity
EG365_08790	COG0271	Belongs to the BolA IbaG family
EG365_08800	COG1192	Involved in chromosome partitioning
EG365_08815	COG0586	Pfam SNARE associated Golgi protein
EG365_08820	COG2259	Doxx family
EG365_08825	COG4399	Belongs to the UPF0754 family
EG365_08830	COG0519	Catalyzes the synthesis of GMP from XMP
EG365_08830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EG365_08875	COG0281	malic enzyme
EG365_08885	COG2837	iron assimilation
EG365_08890	COG1280	lysine exporter protein (LysE YggA)
EG365_08895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EG365_08900	COG1121	(ABC) transporter
EG365_08965	COG0386	Belongs to the glutathione peroxidase family
EG365_08980	COG1309	transcriptional regulator
EG365_08985	COG0697	spore germination
EG365_08995	COG0758	DNA mediated transformation
EG365_09030	COG1309	transcriptional regulator
EG365_09065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EG365_09075	COG0655	NAD(P)H dehydrogenase (quinone) activity
EG365_09110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EG365_09120	COG2814	Major facilitator Superfamily
EG365_09130	COG1253	flavin adenine dinucleotide binding
EG365_09140	COG2860	membrane
EG365_09145	COG0477	Major facilitator Superfamily
EG365_09155	COG0318	PFAM AMP-dependent synthetase and ligase
EG365_09170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EG365_09185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG365_09195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG365_09200	COG0606	chelatase, subunit chli
EG365_09230	COG0589	response to stress
EG365_09235	COG0659	secondary active sulfate transmembrane transporter activity
EG365_09265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EG365_09315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EG365_09395	COG0606	chelatase, subunit chli
EG365_09405	COG0347	Belongs to the P(II) protein family
EG365_09410	COG0004	ammonium transporteR
EG365_09420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EG365_09420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EG365_09460	COG0795	lipopolysaccharide-transporting ATPase activity
EG365_09465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EG365_09470	COG0793	Belongs to the peptidase S41A family
EG365_09485	COG2197	response regulator
EG365_09495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EG365_09505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EG365_09510	COG4974	Belongs to the 'phage' integrase family
EG365_09535	COG0772	Belongs to the SEDS family
EG365_09540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EG365_09545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EG365_09550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EG365_09575	COG0697	spore germination
EG365_09580	COG1538	Outer membrane efflux protein
EG365_09600	COG3275	phosphorelay sensor kinase activity
EG365_09610	COG0181	hydroxymethylbilane synthase activity
EG365_09655	COG1716	ATPase activity
EG365_09660	COG0546	phosphoglycolate phosphatase activity
EG365_09755	COG0596	Alpha beta hydrolase
EG365_09760	COG2056	Na+-H+ antiporter family
EG365_09775	COG0326	Molecular chaperone. Has ATPase activity
EG365_09790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EG365_09860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EG365_09865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EG365_09865	COG2169	Transcriptional regulator
EG365_09895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EG365_09905	COG0497	DNA recombination
EG365_09920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EG365_09930	COG0237	dephospho-CoA kinase activity
EG365_09980	COG0195	Participates in both transcription termination and antitermination
EG365_10000	COG2212	antiporter activity
EG365_10010	COG0651	ATP synthesis coupled electron transport
EG365_10015	COG1006	Multisubunit Na H antiporter MnhC subunit
EG365_10020	COG2111	Na H antiporter
EG365_10020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EG365_10035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EG365_10040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG365_10055	COG2226	methyltransferase
EG365_10075	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EG365_10080	COG1074	ATP-dependent DNA helicase activity
EG365_10085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EG365_10105	COG0598	Magnesium transport protein CorA
EG365_10110	COG0789	Transcriptional regulator
EG365_10115	COG0484	heat shock protein binding
EG365_10125	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EG365_10130	COG0475	glutathione-regulated potassium exporter activity
EG365_10130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EG365_10135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EG365_10155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG365_10165	COG4535	Mg2 and Co2 transporter CorC
EG365_10170	COG0425	Belongs to the sulfur carrier protein TusA family
EG365_10175	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EG365_10175	COG0644	oxidoreductase
EG365_10185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EG365_10200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG365_10205	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EG365_10245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EG365_10260	COG0534	Mate efflux family protein
EG365_10270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EG365_10275	COG4221	oxidoreductase activity
EG365_10280	COG0583	DNA-binding transcription factor activity
EG365_10300	COG1530	ribonuclease E activity
EG365_10315	COG0546	phosphoglycolate phosphatase activity
EG365_10320	COG2378	regulation of single-species biofilm formation
EG365_10325	COG0625	glutathione transferase activity
EG365_10335	COG0583	DNA-binding transcription factor activity
EG365_10400	COG0473	3-isopropylmalate dehydrogenase activity
EG365_10475	COG1301	dicarboxylic acid transport
EG365_10485	COG1560	Kdo2-lipid A biosynthetic process
EG365_10490	COG1280	lysine exporter protein (LysE YggA)
EG365_10510	COG1733	regulation of RNA biosynthetic process
EG365_10535	COG0210	DNA helicase
EG365_10540	COG0724	RNA recognition motif
EG365_10560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EG365_10560	COG4651	solute:proton antiporter activity
EG365_10565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EG365_10570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EG365_10585	COG0788	formyltetrahydrofolate deformylase activity
EG365_10690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EG365_10690	COG2813	Specifically methylates the guanine in position
EG365_10700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EG365_10710	COG4774	siderophore transport
EG365_10720	COG0740	serine-type endopeptidase activity
EG365_10740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EG365_10740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EG365_10745	COG0857	belongs to the CobB CobQ family
EG365_10745	COG0280	phosphate acetyltransferase
EG365_10750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EG365_10760	COG0800	Aldolase
EG365_10770	COG3265	gluconokinase activity
EG365_10775	COG1012	belongs to the aldehyde dehydrogenase family
EG365_10785	COG2267	carboxylic ester hydrolase activity
EG365_10800	COG0793	Belongs to the peptidase S41A family
EG365_10835	COG1426	Protein conserved in bacteria
EG365_10875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG365_10880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EG365_10890	COG0318	PFAM AMP-dependent synthetase and ligase
EG365_10905	COG2986	histidine ammonia-lyase
EG365_10945	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_10950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EG365_10970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EG365_10980	COG1162	GTPase activity
EG365_10985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EG365_11000	COG1538	Outer membrane efflux protein
EG365_11005	COG1136	(ABC) transporter
EG365_11005	COG0577	efflux transmembrane transporter activity
EG365_11010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG365_11035	COG0028	Belongs to the TPP enzyme family
EG365_11040	COG0440	acetolactate synthase activity
EG365_11075	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EG365_11090	COG0084	hydrolase, TatD family'
EG365_11105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EG365_11115	COG0583	DNA-binding transcription factor activity
EG365_11125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EG365_11130	COG2814	Major facilitator Superfamily
EG365_11140	COG0697	spore germination
EG365_11145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EG365_11150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EG365_11155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EG365_11170	COG3622	Belongs to the hyi family
EG365_11175	COG2084	Dehydrogenase
EG365_11180	COG1024	Enoyl-CoA hydratase
EG365_11185	COG5002	protein histidine kinase activity
EG365_11185	COG2205	protein histidine kinase activity
EG365_11185	COG0784	Response regulator, receiver
EG365_11205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EG365_11230	COG3956	TIGRFAM MazG family protein
EG365_11235	COG1555	photosystem II stabilization
EG365_11240	COG0617	tRNA 3'-terminal CCA addition
EG365_11245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EG365_11265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG365_11270	COG3028	Belongs to the UPF0307 family
EG365_11275	COG0318	PFAM AMP-dependent synthetase and ligase
EG365_11295	COG0625	glutathione transferase activity
EG365_11300	COG1238	metal cluster binding
EG365_11315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EG365_11340	COG0072	phenylalanine-tRNA ligase activity
EG365_11370	COG0248	Ppx GppA phosphatase
EG365_11380	COG0037	tRNA processing
EG365_11420	COG1764	response to oxidative stress
EG365_11425	COG1846	Transcriptional regulator
EG365_11435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EG365_11495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EG365_11500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EG365_11505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EG365_11515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EG365_11575	COG1214	PFAM Peptidase M22, glycoprotease
EG365_11600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EG365_11605	COG0561	phosphatase activity
EG365_11615	COG2132	Multicopper oxidase
EG365_11620	COG3667	copper resistance
EG365_11635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EG365_11640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EG365_11645	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EG365_11675	COG1063	alcohol dehydrogenase
EG365_11680	COG0583	DNA-binding transcription factor activity
EG365_11685	COG1960	acyl-CoA dehydrogenase activity
EG365_11690	COG2814	Major facilitator Superfamily
EG365_11695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EG365_11705	COG1053	succinate dehydrogenase
EG365_11710	COG0583	DNA-binding transcription factor activity
EG365_11730	COG0583	DNA-binding transcription factor activity
EG365_11740	COG1473	amidohydrolase
EG365_11760	COG0583	DNA-binding transcription factor activity
EG365_11770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EG365_11775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG365_11805	COG0384	phenazine biosynthesis protein PhzF
EG365_11825	COG4993	Dehydrogenase
EG365_11905	COG2205	protein histidine kinase activity
EG365_11915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EG365_11935	COG0745	RESPONSE REGULATOR receiver
EG365_11940	COG2205	protein histidine kinase activity
EG365_11975	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EG365_12005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EG365_12010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EG365_12030	COG0583	DNA-binding transcription factor activity
EG365_12050	COG0668	transmembrane transport
EG365_12060	COG2081	HI0933 family
EG365_12065	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EG365_12095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG365_12095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EG365_12105	COG0489	protein tyrosine kinase activity
EG365_12165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EG365_12175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EG365_12190	COG0730	response to heat
EG365_12200	COG1196	nuclear chromosome segregation
EG365_12220	COG2223	nitrite transmembrane transporter activity
EG365_12225	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EG365_12230	COG1877	trehalose-phosphatase activity
EG365_12235	COG0596	Alpha beta hydrolase
EG365_12235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EG365_12235	COG2226	methyltransferase
EG365_12250	COG4106	trans-aconitate 2-methyltransferase activity
EG365_12265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EG365_12270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EG365_12275	COG0009	L-threonylcarbamoyladenylate synthase
EG365_12280	COG3101	peptidyl-lysine hydroxylation
EG365_12285	COG1399	metal-binding, possibly nucleic acid-binding protein
EG365_12310	COG1652	LysM domain
EG365_12315	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EG365_12315	COG0352	thiamine-phosphate diphosphorylase activity
EG365_12315	COG0351	phosphomethylpyrimidine kinase
EG365_12325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EG365_12355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EG365_12385	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EG365_12400	COG0358	DNA primase activity
EG365_12410	COG0564	pseudouridine synthase activity
EG365_12435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EG365_12455	COG0583	DNA-binding transcription factor activity
EG365_12460	COG0473	3-isopropylmalate dehydrogenase activity
EG365_12480	COG1012	belongs to the aldehyde dehydrogenase family
EG365_12500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EG365_12500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EG365_12560	COG0456	acetyltransferase
EG365_12570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EG365_12575	COG0492	ferredoxin-NADP+ reductase activity
EG365_12580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EG365_12580	COG1674	ftsk spoiiie
EG365_12585	COG1280	lysine exporter protein (LysE YggA)
EG365_12605	COG2894	cell division
EG365_12620	COG0204	Acyl-transferase
EG365_12625	COG2885	chlorophyll binding
EG365_12630	COG0210	DNA helicase
EG365_12640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EG365_12655	COG0121	glutamine amidotransferase
EG365_12680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EG365_12685	COG0735	belongs to the Fur family
EG365_12710	COG0420	3'-5' exonuclease activity
EG365_12730	COG1090	epimerase
EG365_12745	COG2050	protein possibly involved in aromatic compounds catabolism
EG365_12755	COG2814	Major facilitator Superfamily
EG365_12760	COG0405	Gamma-glutamyltransferase
EG365_12830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EG365_12835	COG4197	protein conserved in bacteria, prophage-related
EG365_12920	COG5410	chromosome segregation
EG365_12925	COG3567	Phage-associated protein, HI1409 family
EG365_12940	COG3566	protein conserved in bacteria
EG365_13115	COG0477	Major facilitator Superfamily
EG365_13120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG365_13145	COG0531	amino acid
EG365_13150	COG2040	homocysteine
EG365_13175	COG1309	transcriptional regulator
EG365_13180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EG365_13185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EG365_13195	COG1607	acyl-coa hydrolase
EG365_13205	COG0523	cobalamin synthesis protein
EG365_13215	COG4681	YaeQ
EG365_13225	COG0726	polysaccharide deacetylase
EG365_13225	COG1649	PFAM Uncharacterised BCR, COG1649
EG365_13230	COG1215	transferase activity, transferring glycosyl groups
EG365_13240	COG1024	Enoyl-CoA hydratase
EG365_13255	COG1414	Transcriptional regulator
EG365_13275	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_13285	COG0446	pyridine nucleotide-disulphide oxidoreductase
EG365_13290	COG2271	Major facilitator Superfamily
EG365_13300	COG2267	carboxylic ester hydrolase activity
EG365_13305	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_13320	COG0028	Belongs to the TPP enzyme family
EG365_13330	COG0477	Major facilitator Superfamily
EG365_13335	COG0242	peptide deformylase activity
EG365_13340	COG2066	Belongs to the glutaminase family
EG365_13345	COG2207	Transcriptional regulator
EG365_13350	COG2223	nitrite transmembrane transporter activity
EG365_13370	COG0583	DNA-binding transcription factor activity
EG365_13375	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_13380	COG2271	Major facilitator Superfamily
EG365_13385	COG3959	Transketolase, thiamine diphosphate binding domain
EG365_13390	COG3958	Transketolase
EG365_13400	COG0306	phosphate transporter
EG365_13420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EG365_13465	COG4181	ATPase activity
EG365_13470	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EG365_13495	COG0583	DNA-binding transcription factor activity
EG365_13505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EG365_13510	COG1773	rubredoxin
EG365_13560	COG2851	Citrate transporter
EG365_13570	COG1253	flavin adenine dinucleotide binding
EG365_13610	COG0804	urea catabolic process
EG365_13620	COG0830	nickel cation binding
EG365_13635	COG0742	ribosomal rna small subunit methyltransferase
EG365_13640	COG0768	penicillin binding
EG365_13665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EG365_13670	COG2878	Part of a membrane complex involved in electron transport
EG365_13675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EG365_13685	COG3384	dioxygenase
EG365_13720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EG365_14105	COG2194	sulfuric ester hydrolase activity
EG365_14140	COG0006	proline dipeptidase activity
EG365_14145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG365_14150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG365_14170	COG1279	arginine transmembrane transporter activity
EG365_14175	COG0583	DNA-binding transcription factor activity
EG365_14215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EG365_14220	COG0741	lytic transglycosylase activity
EG365_14220	COG1388	LysM domain
EG365_14220	COG0741	lytic transglycosylase activity
EG365_14220	COG1388	LysM domain
EG365_14230	COG4174	ABC transporter (Permease)
EG365_14235	COG4239	(ABC) transporter, permease
EG365_14240	COG4172	Belongs to the ABC transporter superfamily
EG365_14260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EG365_14270	COG4251	negative regulation of phosphorylation
EG365_14270	COG5001	Diguanylate cyclase
EG365_14270	COG2203	Gaf domain
EG365_14270	COG3706	GGDEF domain
EG365_14280	COG0446	pyridine nucleotide-disulphide oxidoreductase
EG365_14280	COG1902	pentaerythritol trinitrate reductase activity
EG365_14295	COG4269	membrane
EG365_14320	COG3316	Transposase and inactivated derivatives
EG365_14350	COG3316	Transposase and inactivated derivatives
EG365_14360	COG0300	oxidoreductase activity
EG365_14370	COG1309	transcriptional regulator
EG365_14375	COG1741	Belongs to the pirin family
EG365_14390	COG2072	flavoprotein involved in K transport
EG365_14400	COG2252	PERMEase
EG365_14405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EG365_14410	COG3038	cytochrome b561
EG365_14420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EG365_14440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EG365_14450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EG365_14465	COG0667	Aldo Keto reductase
EG365_14475	COG1765	OsmC-like protein
EG365_14525	COG2885	chlorophyll binding
EG365_14535	COG0625	glutathione transferase activity
EG365_14540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EG365_14560	COG3634	alkyl hydroperoxide reductase activity
EG365_14570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EG365_14580	COG0450	alkyl hydroperoxide reductase
EG365_14585	COG1643	Atp-dependent helicase
EG365_14600	COG2814	Major facilitator Superfamily
EG365_14605	COG3135	benzoate transporter
EG365_14610	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_14615	COG0543	2 iron, 2 sulfur cluster binding
EG365_14615	COG0633	Ferredoxin
EG365_14620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EG365_14625	COG4638	Rieske (2fe-2S)
EG365_14630	COG0583	DNA-binding transcription factor activity
EG365_14685	COG1570	exodeoxyribonuclease VII activity
EG365_14720	COG1280	lysine exporter protein (LysE YggA)
EG365_14725	COG1278	Cold shock
EG365_14765	COG2814	Major facilitator Superfamily
EG365_14770	COG1733	regulation of RNA biosynthetic process
EG365_14805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EG365_14805	COG0517	IMP dehydrogenase activity
EG365_14810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EG365_14820	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EG365_14825	COG1137	ATPase activity
EG365_14835	COG1538	Outer membrane efflux protein
EG365_14875	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EG365_14890	COG1522	sequence-specific DNA binding
EG365_14895	COG5006	permease, DMT superfamily
EG365_14905	COG1560	Kdo2-lipid A biosynthetic process
EG365_14920	COG2814	Major facilitator Superfamily
EG365_14945	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG365_14980	COG3501	Rhs element vgr protein
EG365_14985	COG3209	COG3209 Rhs family protein
EG365_15000	COG0583	DNA-binding transcription factor activity
EG365_15005	COG1914	H( )-stimulated, divalent metal cation uptake system
EG365_15025	COG4770	biotin carboxylase activity
EG365_15030	COG0038	chloride channel
EG365_15055	COG1309	transcriptional regulator
EG365_15065	COG1063	alcohol dehydrogenase
EG365_15080	COG0439	Biotin carboxylase
EG365_15085	COG2249	NAD(P)H dehydrogenase (quinone) activity
EG365_15105	COG0864	Transcriptional regulator
EG365_15115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG365_15120	COG1116	anion transmembrane transporter activity
EG365_15190	COG2885	chlorophyll binding
EG365_15190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EG365_15230	COG0583	DNA-binding transcription factor activity
EG365_15240	COG0590	tRNA wobble adenosine to inosine editing
EG365_15245	COG2807	transmembrane transport
EG365_15260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EG365_15270	COG0789	Transcriptional regulator
EG365_15285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EG365_15305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG365_15315	COG0446	pyridine nucleotide-disulphide oxidoreductase
EG365_15340	COG1012	belongs to the aldehyde dehydrogenase family
EG365_15345	COG0531	amino acid
EG365_15350	COG1760	l-serine dehydratase
EG365_15355	COG1012	belongs to the aldehyde dehydrogenase family
EG365_15355	COG2030	dehydratase
EG365_15360	COG3396	Phenylacetate-CoA oxygenase
EG365_15365	COG3460	Phenylacetate-CoA oxygenase
EG365_15370	COG3396	Phenylacetate-CoA oxygenase
EG365_15375	COG2151	metal-sulfur cluster biosynthetic enzyme
EG365_15380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG365_15385	COG1024	Enoyl-CoA hydratase
EG365_15390	COG1024	Enoyl-CoA hydratase
EG365_15395	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG365_15400	COG0183	Belongs to the thiolase family
EG365_15405	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EG365_15410	COG3327	negative regulation of DNA-templated transcription, initiation
EG365_15420	COG2050	protein possibly involved in aromatic compounds catabolism
EG365_15460	COG0753	catalase activity
EG365_15465	COG3038	cytochrome b561
EG365_15485	COG2267	carboxylic ester hydrolase activity
EG365_15490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG365_15495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EG365_15500	COG1012	belongs to the aldehyde dehydrogenase family
EG365_15510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EG365_15520	COG1012	belongs to the aldehyde dehydrogenase family
EG365_15525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EG365_15530	COG0583	DNA-binding transcription factor activity
EG365_15540	COG1414	Transcriptional regulator
EG365_15545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EG365_15555	COG1840	ABC-type Fe3 transport system, periplasmic component
EG365_15560	COG3842	ATPase activity
EG365_15575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EG365_15580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EG365_15585	COG2814	Major facilitator Superfamily
EG365_15590	COG1960	acyl-CoA dehydrogenase activity
EG365_15605	COG1024	Enoyl-CoA hydratase
EG365_15615	COG2814	Major facilitator Superfamily
EG365_15625	COG0183	Belongs to the thiolase family
EG365_15630	COG1250	3-hydroxyacyl-CoA dehydrogenase
EG365_15635	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_15640	COG1024	Enoyl-CoA hydratase
EG365_15645	COG1960	acyl-CoA dehydrogenase activity
EG365_15650	COG2814	Major facilitator Superfamily
EG365_15655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG365_15660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG365_15670	COG2814	Major facilitator Superfamily
EG365_15680	COG1960	acyl-CoA dehydrogenase activity
EG365_15695	COG0583	DNA-binding transcription factor activity
EG365_15710	COG1024	Enoyl-CoA hydratase
EG365_15715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EG365_15720	COG1960	acyl-CoA dehydrogenase activity
EG365_15725	COG1309	transcriptional regulator
EG365_15730	COG0318	PFAM AMP-dependent synthetase and ligase
EG365_15750	COG0583	DNA-binding transcription factor activity
EG365_15790	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_15810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EG365_15830	COG0784	Response regulator, receiver
EG365_15830	COG2205	protein histidine kinase activity
EG365_15850	COG0765	amino acid transport
EG365_15855	COG0765	amino acid transport
EG365_15860	COG1126	abc transporter atp-binding protein
EG365_15865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG365_15870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EG365_15885	COG1280	lysine exporter protein (LysE YggA)
EG365_15895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EG365_15900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EG365_15905	COG1045	serine acetyltransferase
EG365_15920	COG0583	DNA-binding transcription factor activity
EG365_15925	COG0625	glutathione transferase activity
EG365_15930	COG0625	glutathione transferase activity
EG365_15935	COG0583	DNA-binding transcription factor activity
EG365_15945	COG1346	cytolysis
EG365_15965	COG2814	Major facilitator Superfamily
EG365_15975	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EG365_15980	COG3052	prosthetic group binding
EG365_16000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EG365_16020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EG365_16030	COG1294	oxidase, subunit
EG365_16035	COG1271	oxidase subunit
EG365_16060	COG0477	Major facilitator Superfamily
EG365_16085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EG365_16090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EG365_16095	COG2175	clavaminate synthase activity
EG365_16105	COG1953	Uracil, thiamine, allantoin
EG365_16115	COG0583	DNA-binding transcription factor activity
EG365_16125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EG365_16140	COG0640	Transcriptional regulator
EG365_16145	COG0798	PFAM Bile acid sodium symporter
EG365_16150	COG0583	DNA-binding transcription factor activity
EG365_16165	COG3634	alkyl hydroperoxide reductase activity
EG365_16205	COG0436	Aminotransferase
EG365_16215	COG0386	Belongs to the glutathione peroxidase family
EG365_16255	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EG365_16280	COG0012	GTP binding
EG365_16285	COG2011	ABC-type metal ion transport system permease component
EG365_16290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EG365_16300	COG1464	Belongs to the NlpA lipoprotein family
EG365_16330	COG0765	amino acid transport
EG365_16335	COG0765	amino acid transport
EG365_16340	COG1126	abc transporter atp-binding protein
EG365_16350	COG1522	sequence-specific DNA binding
EG365_16365	COG1309	transcriptional regulator
EG365_16385	COG0583	DNA-binding transcription factor activity
EG365_16395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EG365_16405	COG0697	spore germination
EG365_16435	COG3121	Chaperone
EG365_16440	COG3539	Fimbrial protein
EG365_16465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EG365_16465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EG365_16510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EG365_16520	COG2353	YceI-like domain
EG365_16530	COG3698	Phosphodiester glycosidase
EG365_16545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EG365_16550	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EG365_16550	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EG365_16550	COG0506	proline dehydrogenase activity
EG365_16560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EG365_16565	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EG365_16585	COG1132	(ABC) transporter
EG365_16590	COG3122	Protein conserved in bacteria
EG365_16595	COG3619	membrane
EG365_16605	COG0640	Transcriptional regulator
EG365_16615	COG2850	peptidyl-arginine hydroxylation
EG365_16620	COG0424	maF-like protein
EG365_16640	COG0191	fructose-bisphosphate aldolase activity
EG365_16645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG365_16660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EG365_16670	COG1192	Involved in chromosome partitioning
EG365_16675	COG1475	DNA binding
EG365_16680	COG0811	peptide transport
EG365_16690	COG1132	(ABC) transporter
EG365_16695	COG1663	tetraacyldisaccharide 4'-kinase activity
EG365_16715	COG0084	hydrolase, TatD family'
EG365_16730	COG2165	general secretion pathway protein
EG365_16760	COG0590	tRNA wobble adenosine to inosine editing
EG365_16780	COG0776	regulation of translation
EG365_16810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EG365_16815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EG365_16865	COG0339	signal peptide processing
EG365_16875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EG365_16910	COG0702	epimerase
EG365_16915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EG365_16935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EG365_16965	COG0316	Belongs to the HesB IscA family
EG365_16970	COG0822	iron-sulfur transferase activity
EG365_16995	COG0776	regulation of translation
EG365_17000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EG365_17005	COG2207	Transcriptional regulator
EG365_17010	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EG365_17015	COG1960	acyl-CoA dehydrogenase activity
EG365_17020	COG1960	acyl-CoA dehydrogenase activity
EG365_17035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EG365_17050	COG2814	Major facilitator Superfamily
EG365_17055	COG4264	IucA IucC family
EG365_17060	COG4264	IucA IucC family
EG365_17120	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EG365_17140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EG365_17145	COG0730	response to heat
EG365_17165	COG4773	Receptor
EG365_17170	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG365_17185	COG1131	(ABC) transporter
EG365_17190	COG0842	Transport permease protein
EG365_17195	COG0842	Transport permease protein
EG365_17250	COG2226	methyltransferase
EG365_17275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EG365_17310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EG365_17320	COG0133	tryptophan synthase activity
EG365_17335	COG3706	GGDEF domain
EG365_17350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EG365_17355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EG365_17360	COG0022	dehydrogenase e1 component
EG365_17365	COG0508	dehydrogenase complex catalyzes the overall conversion of
EG365_17370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EG365_17380	COG1063	alcohol dehydrogenase
EG365_17385	COG3781	membrane
EG365_17395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EG365_17395	COG3453	Protein conserved in bacteria
EG365_17405	COG0730	response to heat
EG365_17420	COG2207	Transcriptional regulator
EG365_17420	COG3708	Transcriptional regulator
EG365_17425	COG1733	regulation of RNA biosynthetic process
EG365_17430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EG365_17455	COG4521	taurine ABC transporter
EG365_17460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EG365_17480	COG0477	Major facilitator Superfamily
EG365_17490	COG1027	Aspartate ammonia-lyase
EG365_17505	COG0583	DNA-binding transcription factor activity
EG365_17510	COG0583	DNA-binding transcription factor activity
EG365_17515	COG0183	Belongs to the thiolase family
EG365_17520	COG2031	fatty acid transporter
EG365_17525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG365_17535	COG0583	DNA-binding transcription factor activity
EG365_17545	COG2610	gluconate transmembrane transporter activity
EG365_17550	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_17555	COG2207	Transcriptional regulator
EG365_17565	COG0412	Dienelactone hydrolase
EG365_17570	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_17580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG365_17595	COG0543	2 iron, 2 sulfur cluster binding
EG365_17595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EG365_17600	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EG365_17605	COG4638	Rieske (2fe-2S)
EG365_17615	COG0725	ABC transporter, periplasmic molybdate-binding protein
EG365_17620	COG4149	molybdate abc transporter
EG365_17625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EG365_17630	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_17635	COG3433	isochorismatase activity
EG365_17635	COG1535	isochorismatase
EG365_17700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EG365_17715	COG0753	catalase activity
EG365_17725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EG365_17770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EG365_17790	COG2072	flavoprotein involved in K transport
EG365_17800	COG1538	Outer membrane efflux protein
EG365_17805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EG365_17810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EG365_17815	COG0745	RESPONSE REGULATOR receiver
EG365_17820	COG2205	protein histidine kinase activity
EG365_17830	COG2207	Transcriptional regulator
EG365_17845	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_17895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EG365_18015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EG365_18035	COG1120	ATPase activity
EG365_18050	COG1064	alcohol dehydrogenase
EG365_18065	COG2207	Transcriptional regulator
EG365_18070	COG2084	Dehydrogenase
EG365_18080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EG365_18085	COG0583	DNA-binding transcription factor activity
EG365_18095	COG0129	dihydroxy-acid dehydratase activity
EG365_18100	COG1012	belongs to the aldehyde dehydrogenase family
EG365_18115	COG1566	PFAM secretion protein HlyD family protein
EG365_18135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EG365_18140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EG365_18165	COG0583	DNA-binding transcription factor activity
EG365_18210	COG3210	domain, Protein
EG365_18215	COG2831	hemolysin activation secretion protein
EG365_18230	COG1473	amidohydrolase
EG365_18240	COG0475	glutathione-regulated potassium exporter activity
EG365_18240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EG365_18250	COG0583	DNA-binding transcription factor activity
EG365_18255	COG1335	isochorismatase
EG365_18265	COG1309	transcriptional regulator
EG365_18295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EG365_18305	COG0446	pyridine nucleotide-disulphide oxidoreductase
EG365_18305	COG1902	pentaerythritol trinitrate reductase activity
EG365_18310	COG1846	Transcriptional regulator
EG365_18335	COG0753	catalase activity
EG365_18350	COG1012	belongs to the aldehyde dehydrogenase family
EG365_18365	COG3162	membrane
EG365_18375	COG3829	transcription factor binding
EG365_18380	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_18385	COG1960	acyl-CoA dehydrogenase activity
EG365_18405	COG1012	belongs to the aldehyde dehydrogenase family
EG365_18425	COG2186	Transcriptional regulator
EG365_18435	COG0583	DNA-binding transcription factor activity
EG365_18440	COG4948	Mandelate Racemase Muconate Lactonizing
EG365_18445	COG4829	muconolactone delta-isomerase
EG365_18455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG365_18460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG365_18465	COG0183	Belongs to the thiolase family
EG365_18470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EG365_18480	COG1012	belongs to the aldehyde dehydrogenase family
EG365_18490	COG3733	amine oxidase
EG365_18500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EG365_18510	COG1028	Short-chain dehydrogenase reductase Sdr
EG365_18520	COG4638	Rieske (2fe-2S)
EG365_18540	COG0154	amidase activity
EG365_18550	COG2814	Major facilitator Superfamily
EG365_18575	COG1960	acyl-CoA dehydrogenase activity
EG365_18580	COG0583	DNA-binding transcription factor activity
EG365_18585	COG1414	Transcriptional regulator
EG365_18600	COG2391	methyltransferase activity
EG365_18610	COG4993	Dehydrogenase
EG365_18615	COG3659	wide pore channel activity
EG365_18620	COG3420	alginic acid biosynthetic process
EG365_18625	COG0710	3-dehydroquinate dehydratase activity
EG365_18630	COG3485	protocatechuate 3,4-dioxygenase
EG365_18635	COG3485	protocatechuate 3,4-dioxygenase
EG365_18640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EG365_18645	COG2271	Major facilitator Superfamily
EG365_18650	COG0596	Alpha beta hydrolase
EG365_18655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EG365_18660	COG0183	Belongs to the thiolase family
EG365_18665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EG365_18670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EG365_18680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EG365_18685	COG2323	membrane
EG365_18730	COG1902	pentaerythritol trinitrate reductase activity
EG365_18730	COG0446	pyridine nucleotide-disulphide oxidoreductase
EG365_18745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EG365_18755	COG0542	response to heat
EG365_18760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EG365_18790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EG365_18795	COG0569	domain protein
EG365_18800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EG365_18815	COG4774	siderophore transport
EG365_18820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EG365_18830	COG1585	Membrane protein implicated in regulation of membrane protease activity
EG365_18845	COG1294	oxidase, subunit
EG365_18850	COG4890	Cyd operon protein YbgT
EG365_18865	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EG365_18875	COG0552	protein localization to endoplasmic reticulum
EG365_18900	COG0517	IMP dehydrogenase activity
EG365_18900	COG0516	GMP reductase activity
EG365_18905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EG365_18910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EG365_18920	COG0583	DNA-binding transcription factor activity
EG365_18925	COG0024	Methionine aminopeptidase
EG365_18955	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EG365_18955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EG365_18960	COG1105	Belongs to the carbohydrate kinase PfkB family
EG365_18965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EG365_18965	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EG365_18965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EG365_18985	COG5001	Diguanylate cyclase
EG365_18985	COG3300	MHYT domain
EG365_19000	COG2135	peptidase activity
EG365_19005	COG0659	secondary active sulfate transmembrane transporter activity
EG365_19020	COG1113	amino acid transport
EG365_19030	COG1522	sequence-specific DNA binding
EG365_19055	COG1011	Hydrolase
EG365_19060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EG365_19070	COG2137	regulation of response to DNA damage stimulus
EG365_19085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EG365_19120	COG0575	Belongs to the CDS family
EG365_19125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EG365_19145	COG3852	Histidine kinase
EG365_19150	COG2204	response regulator
EG365_19210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EG365_19215	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EG365_19235	COG0697	spore germination