locus-tag	class	description
MN200_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MN200_00010	COG0592	DNA-directed DNA polymerase activity
MN200_00020	COG0187	DNA topoisomerase II activity
MN200_00030	COG0488	(ABC) transporter
MN200_00090	COG0657	acetylesterase activity
MN200_00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MN200_00130	COG2133	pyrroloquinoline quinone binding
MN200_00160	COG1047	Peptidyl-prolyl cis-trans
MN200_00165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MN200_00170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MN200_00175	COG0196	riboflavin kinase activity
MN200_00190	COG1309	transcriptional regulator
MN200_00195	COG1116	anion transmembrane transporter activity
MN200_00200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MN200_00205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MN200_00210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MN200_00215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MN200_00220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MN200_00220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MN200_00245	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_00250	COG0546	phosphoglycolate phosphatase activity
MN200_00255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MN200_00260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MN200_00265	COG3307	-O-antigen
MN200_00275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MN200_00285	COG3023	N-Acetylmuramoyl-L-alanine amidase
MN200_00290	COG0728	peptidoglycan biosynthetic process
MN200_00320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MN200_00345	COG0438	transferase activity, transferring glycosyl groups
MN200_00350	COG0438	transferase activity, transferring glycosyl groups
MN200_00355	COG0438	transferase activity, transferring glycosyl groups
MN200_00365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MN200_00375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MN200_00405	COG2244	polysaccharide biosynthetic process
MN200_00420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MN200_00430	COG0438	transferase activity, transferring glycosyl groups
MN200_00435	COG0297	glycogen (starch) synthase activity
MN200_00440	COG0662	Cupin 2, conserved barrel domain protein
MN200_00440	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MN200_00450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MN200_00465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MN200_00475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MN200_00480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MN200_00490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MN200_00495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MN200_00505	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MN200_00520	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MN200_00525	COG0583	DNA-binding transcription factor activity
MN200_00545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MN200_00555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MN200_00570	COG2986	histidine ammonia-lyase
MN200_00610	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_00615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MN200_00640	COG0271	Belongs to the BolA IbaG family
MN200_00650	COG1192	Involved in chromosome partitioning
MN200_00665	COG0586	Pfam SNARE associated Golgi protein
MN200_00680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MN200_00680	COG0519	Catalyzes the synthesis of GMP from XMP
MN200_00735	COG0281	malic enzyme
MN200_00745	COG1388	LysM domain
MN200_00745	COG3409	Peptidoglycan-binding domain 1 protein
MN200_00745	COG5632	N-Acetylmuramoyl-L-alanine amidase
MN200_00755	COG2837	iron assimilation
MN200_00765	COG1683	Conserved Protein
MN200_00770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MN200_00775	COG1121	(ABC) transporter
MN200_00825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MN200_00860	COG0386	Belongs to the glutathione peroxidase family
MN200_00870	COG0697	spore germination
MN200_00880	COG0758	DNA mediated transformation
MN200_00955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MN200_00965	COG2814	Major facilitator Superfamily
MN200_00985	COG1253	flavin adenine dinucleotide binding
MN200_00990	COG3012	SEC-C Motif Domain Protein
MN200_00995	COG2860	membrane
MN200_01000	COG0477	Major facilitator Superfamily
MN200_01010	COG0318	PFAM AMP-dependent synthetase and ligase
MN200_01025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MN200_01090	COG0633	Ferredoxin
MN200_01130	COG2814	Major facilitator Superfamily
MN200_01160	COG0789	Transcriptional regulator
MN200_01170	COG0640	Transcriptional regulator
MN200_01180	COG1230	cation diffusion facilitator family transporter
MN200_01185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MN200_01255	COG2826	transposase and inactivated derivatives, IS30 family
MN200_01275	COG0347	Belongs to the P(II) protein family
MN200_01280	COG0004	ammonium transporteR
MN200_01290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MN200_01290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MN200_01305	COG0586	Pfam SNARE associated Golgi protein
MN200_01325	COG0795	lipopolysaccharide-transporting ATPase activity
MN200_01330	COG0795	lipopolysaccharide-transporting ATPase activity
MN200_01335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MN200_01340	COG0793	Belongs to the peptidase S41A family
MN200_01355	COG2197	response regulator
MN200_01360	COG1686	Belongs to the peptidase S11 family
MN200_01365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MN200_01375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MN200_01380	COG4974	Belongs to the 'phage' integrase family
MN200_01400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MN200_01405	COG0772	Belongs to the SEDS family
MN200_01410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MN200_01415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MN200_01420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MN200_01430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MN200_01440	COG1538	Outer membrane efflux protein
MN200_01460	COG3275	phosphorelay sensor kinase activity
MN200_01470	COG0181	hydroxymethylbilane synthase activity
MN200_01490	COG0824	Thioesterase
MN200_01520	COG0546	phosphoglycolate phosphatase activity
MN200_01570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MN200_01575	COG0081	regulation of translation
MN200_01580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MN200_01585	COG0222	ribosome binding
MN200_01590	COG0085	RNA polymerase activity
MN200_01595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MN200_01625	COG2056	Na+-H+ antiporter family
MN200_01630	COG3047	cAMP biosynthetic process
MN200_01640	COG0326	Molecular chaperone. Has ATPase activity
MN200_01670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MN200_01705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MN200_01750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MN200_01755	COG1132	(ABC) transporter
MN200_01770	COG1289	transmembrane transporter activity
MN200_01785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MN200_01795	COG0497	DNA recombination
MN200_01805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MN200_01815	COG0237	dephospho-CoA kinase activity
MN200_01875	COG0195	Participates in both transcription termination and antitermination
MN200_01885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MN200_01890	COG1320	monovalent cation:proton antiporter activity
MN200_01895	COG2212	antiporter activity
MN200_01900	COG1863	multisubunit Na H antiporter MnhE subunit
MN200_01905	COG0651	ATP synthesis coupled electron transport
MN200_01910	COG1006	Multisubunit Na H antiporter MnhC subunit
MN200_01915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MN200_01915	COG2111	Na H antiporter
MN200_01920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MN200_01930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MN200_01950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MN200_01980	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MN200_01985	COG1074	ATP-dependent DNA helicase activity
MN200_01990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MN200_01995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MN200_02005	COG1185	polyribonucleotide nucleotidyltransferase activity
MN200_02010	COG0598	Magnesium transport protein CorA
MN200_02015	COG2841	Protein conserved in bacteria
MN200_02035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MN200_02045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MN200_02065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN200_02070	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MN200_02075	COG4535	Mg2 and Co2 transporter CorC
MN200_02080	COG0425	Belongs to the sulfur carrier protein TusA family
MN200_02090	COG0644	oxidoreductase
MN200_02090	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MN200_02100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MN200_02110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MN200_02115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MN200_02120	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MN200_02130	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MN200_02130	COG0493	'glutamate synthase
MN200_02145	COG2226	methyltransferase
MN200_02160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MN200_02190	COG0751	glycine-tRNA ligase activity
MN200_02210	COG1983	PspC domain protein
MN200_02235	COG0318	PFAM AMP-dependent synthetase and ligase
MN200_02240	COG1530	ribonuclease E activity
MN200_02245	COG0564	pseudouridine synthase activity
MN200_02260	COG0583	DNA-binding transcription factor activity
MN200_02275	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MN200_02295	COG1960	acyl-CoA dehydrogenase activity
MN200_02310	COG1280	lysine exporter protein (LysE YggA)
MN200_02345	COG0583	DNA-binding transcription factor activity
MN200_02355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MN200_02370	COG0473	3-isopropylmalate dehydrogenase activity
MN200_02425	COG1560	Kdo2-lipid A biosynthetic process
MN200_02430	COG0488	(ABC) transporter
MN200_02435	COG2900	Belongs to the SlyX family
MN200_02475	COG1929	Belongs to the glycerate kinase type-1 family
MN200_02480	COG0210	DNA helicase
MN200_02505	COG4651	solute:proton antiporter activity
MN200_02505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MN200_02530	COG0788	formyltetrahydrofolate deformylase activity
MN200_02635	COG2813	Specifically methylates the guanine in position
MN200_02635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MN200_02645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MN200_02660	COG4774	siderophore transport
MN200_02665	COG4771	TonB-dependent receptor
MN200_02675	COG0740	serine-type endopeptidase activity
MN200_02695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MN200_02695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MN200_02705	COG1917	Cupin 2, conserved barrel domain protein
MN200_02705	COG2207	Transcriptional regulator
MN200_02715	COG2318	DinB family
MN200_02725	COG0280	phosphate acetyltransferase
MN200_02725	COG0857	belongs to the CobB CobQ family
MN200_02730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MN200_02740	COG2267	carboxylic ester hydrolase activity
MN200_02755	COG0793	Belongs to the peptidase S41A family
MN200_02765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MN200_02780	COG0084	hydrolase, TatD family'
MN200_02790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MN200_02805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MN200_02895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MN200_02900	COG0210	DNA helicase
MN200_02960	COG2814	Major facilitator Superfamily
MN200_02985	COG0004	ammonium transporteR
MN200_03000	COG3622	Belongs to the hyi family
MN200_03005	COG2084	Dehydrogenase
MN200_03010	COG1024	Enoyl-CoA hydratase
MN200_03015	COG2205	protein histidine kinase activity
MN200_03015	COG0784	Response regulator, receiver
MN200_03015	COG5002	protein histidine kinase activity
MN200_03020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MN200_03035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MN200_03045	COG3956	TIGRFAM MazG family protein
MN200_03050	COG1555	photosystem II stabilization
MN200_03055	COG0617	tRNA 3'-terminal CCA addition
MN200_03060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MN200_03070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MN200_03075	COG1660	Displays ATPase and GTPase activities
MN200_03085	COG3028	Belongs to the UPF0307 family
MN200_03090	COG0318	PFAM AMP-dependent synthetase and ligase
MN200_03120	COG0625	glutathione transferase activity
MN200_03130	COG1238	metal cluster binding
MN200_03180	COG0072	phenylalanine-tRNA ligase activity
MN200_03205	COG0248	Ppx GppA phosphatase
MN200_03215	COG0037	tRNA processing
MN200_03230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MN200_03230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MN200_03260	COG1764	response to oxidative stress
MN200_03270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MN200_03280	COG2208	phosphoserine phosphatase activity
MN200_03285	COG2853	Lipoprotein
MN200_03315	COG2814	Major facilitator Superfamily
MN200_03330	COG0693	protein deglycase activity
MN200_03355	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MN200_03365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MN200_03390	COG0494	nUDIX hydrolase
MN200_03395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MN200_03400	COG1214	PFAM Peptidase M22, glycoprotease
MN200_03405	COG1968	undecaprenyl-diphosphatase activity
MN200_03455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MN200_03465	COG2132	Multicopper oxidase
MN200_03490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MN200_03500	COG0352	thiamine-phosphate diphosphorylase activity
MN200_03500	COG0351	phosphomethylpyrimidine kinase
MN200_03500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MN200_03530	COG0251	oxidation-reduction process
MN200_03535	COG1113	amino acid transport
MN200_03545	COG1981	membrane
MN200_03560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MN200_03585	COG0456	acetyltransferase
MN200_03595	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MN200_03600	COG0492	ferredoxin-NADP+ reductase activity
MN200_03605	COG1674	ftsk spoiiie
MN200_03605	COG0531	amino acid
MN200_03615	COG3335	DDE superfamily endonuclease
MN200_03630	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MN200_03640	COG0850	regulation of cytokinetic process
MN200_03650	COG0204	Acyl-transferase
MN200_03655	COG2885	chlorophyll binding
MN200_03660	COG0210	DNA helicase
MN200_03665	COG0756	dUTP diphosphatase activity
MN200_03680	COG0121	glutamine amidotransferase
MN200_03695	COG2914	Belongs to the UPF0125 (RnfH) family
MN200_03700	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MN200_03705	COG0735	belongs to the Fur family
MN200_03735	COG0420	3'-5' exonuclease activity
MN200_03740	COG4251	negative regulation of phosphorylation
MN200_03740	COG5001	Diguanylate cyclase
MN200_03740	COG2203	Gaf domain
MN200_03740	COG3706	GGDEF domain
MN200_03750	COG1090	epimerase
MN200_03765	COG2050	protein possibly involved in aromatic compounds catabolism
MN200_03770	COG1566	PFAM secretion protein HlyD family protein
MN200_03775	COG2814	Major facilitator Superfamily
MN200_03780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MN200_03790	COG0582	viral genome integration into host DNA
MN200_03830	COG2184	nucleotidyltransferase activity
MN200_03860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MN200_03945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MN200_03950	COG3177	Filamentation induced by cAMP protein fic
MN200_04010	COG2323	membrane
MN200_04045	COG2351	hydroxyisourate hydrolase activity
MN200_04060	COG3046	protein related to deoxyribodipyrimidine photolyase
MN200_04065	COG2816	NAD+ diphosphatase activity
MN200_04105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MN200_04120	COG0642	Histidine kinase
MN200_04220	COG4221	oxidoreductase activity
MN200_04225	COG0583	DNA-binding transcription factor activity
MN200_04230	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MN200_04235	COG3321	synthase
MN200_04235	COG0604	alcohol dehydrogenase
MN200_04240	COG3293	Transposase
MN200_04255	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MN200_04285	COG1522	sequence-specific DNA binding
MN200_04305	COG1346	cytolysis
MN200_04315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MN200_04325	COG1294	oxidase, subunit
MN200_04345	COG4772	TonB-dependent receptor
MN200_04355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MN200_04365	COG0583	DNA-binding transcription factor activity
MN200_04370	COG2610	gluconate transmembrane transporter activity
MN200_04375	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_04390	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MN200_04435	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MN200_04445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MN200_04450	COG1077	Cell shape determining protein MreB Mrl
MN200_04455	COG1792	Involved in formation and maintenance of cell shape
MN200_04460	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MN200_04465	COG0424	maF-like protein
MN200_04480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MN200_04530	COG0640	Transcriptional regulator
MN200_04540	COG0798	PFAM Bile acid sodium symporter
MN200_04545	COG0431	NADPH-dependent FMN reductase
MN200_04560	COG0625	glutathione transferase activity
MN200_04580	COG1113	amino acid transport
MN200_04595	COG1113	amino acid transport
MN200_04600	COG2828	Protein conserved in bacteria
MN200_04605	COG0142	geranyltranstransferase activity
MN200_04620	COG1752	Esterase of the alpha-beta hydrolase superfamily
MN200_04645	COG0745	RESPONSE REGULATOR receiver
MN200_04650	COG0642	Histidine kinase
MN200_04665	COG0004	ammonium transporteR
MN200_04675	COG1126	abc transporter atp-binding protein
MN200_04680	COG0765	amino acid transport
MN200_04685	COG0765	amino acid transport
MN200_04705	COG0668	transmembrane transport
MN200_04720	COG2081	HI0933 family
MN200_04755	COG4716	Myosin-crossreactive antigen
MN200_04790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN200_04790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MN200_04825	COG0489	protein tyrosine kinase activity
MN200_04840	COG2358	TRAP transporter, solute receptor (TAXI family
MN200_04910	COG0840	transmembrane signaling receptor activity
MN200_04915	COG2198	Histidine kinase
MN200_04915	COG0643	Histidine kinase
MN200_04915	COG0784	Response regulator, receiver
MN200_04925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MN200_04940	COG2832	Protein of unknown function (DUF454)
MN200_05010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MN200_05020	COG1289	transmembrane transporter activity
MN200_05025	COG2814	Major facilitator Superfamily
MN200_05040	COG0786	glutamate:sodium symporter activity
MN200_05045	COG1115	amino acid carrier protein
MN200_05055	COG1752	Esterase of the alpha-beta hydrolase superfamily
MN200_05060	COG1607	acyl-coa hydrolase
MN200_05070	COG0523	cobalamin synthesis protein
MN200_05075	COG4681	YaeQ
MN200_05085	COG2199	diguanylate cyclase activity
MN200_05085	COG2203	Gaf domain
MN200_05130	COG0477	Major facilitator Superfamily
MN200_05135	COG0242	peptide deformylase activity
MN200_05145	COG2223	nitrite transmembrane transporter activity
MN200_05160	COG2852	Protein conserved in bacteria
MN200_05175	COG0306	phosphate transporter
MN200_05200	COG4771	TonB-dependent receptor
MN200_05225	COG4181	ATPase activity
MN200_05230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MN200_05250	COG0583	DNA-binding transcription factor activity
MN200_05260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MN200_05265	COG1773	rubredoxin
MN200_05270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MN200_05305	COG1695	Transcriptional regulator
MN200_05320	COG0604	alcohol dehydrogenase
MN200_05320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MN200_05320	COG3321	synthase
MN200_05320	COG4221	oxidoreductase activity
MN200_05360	COG0477	Major facilitator Superfamily
MN200_05380	COG1597	lipid kinase activity
MN200_05400	COG0641	radical SAM
MN200_05405	COG3119	arylsulfatase activity
MN200_05430	COG0742	ribosomal rna small subunit methyltransferase
MN200_05435	COG0768	penicillin binding
MN200_05460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MN200_05465	COG2878	Part of a membrane complex involved in electron transport
MN200_05470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MN200_05480	COG3384	dioxygenase
MN200_05490	COG2234	aminopeptidase activity
MN200_05505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MN200_05515	COG2217	Heavy metal translocating P-type atpase
MN200_05520	COG0583	DNA-binding transcription factor activity
MN200_05545	COG4770	biotin carboxylase activity
MN200_05555	COG3177	Filamentation induced by cAMP protein fic
MN200_05590	COG0006	proline dipeptidase activity
MN200_05620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MN200_05625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MN200_05645	COG2915	High frequency lysogenization protein hflD homolog
MN200_05660	COG4589	Belongs to the CDS family
MN200_05675	COG2453	phosphatase
MN200_05675	COG0671	phosphoesterase, PA-phosphatase related
MN200_05680	COG2267	carboxylic ester hydrolase activity
MN200_05685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MN200_05690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MN200_05695	COG1686	Belongs to the peptidase S11 family
MN200_05715	COG0753	catalase activity
MN200_05730	COG1388	LysM domain
MN200_05730	COG4942	peptidase
MN200_05735	COG0583	DNA-binding transcription factor activity
MN200_05755	COG0657	acetylesterase activity
MN200_05770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MN200_05775	COG0741	lytic transglycosylase activity
MN200_05775	COG1388	LysM domain
MN200_05780	COG4166	transmembrane transport
MN200_05785	COG4174	ABC transporter (Permease)
MN200_05790	COG4239	(ABC) transporter, permease
MN200_05795	COG4172	Belongs to the ABC transporter superfamily
MN200_05810	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MN200_05835	COG0833	amino acid
MN200_05855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MN200_05860	COG0418	dihydroorotase activity
MN200_05865	COG5001	Diguanylate cyclase
MN200_05865	COG4251	negative regulation of phosphorylation
MN200_05865	COG3706	GGDEF domain
MN200_05865	COG2203	Gaf domain
MN200_05880	COG2186	Transcriptional regulator
MN200_05890	COG0277	FAD linked oxidase domain protein
MN200_05895	COG1902	pentaerythritol trinitrate reductase activity
MN200_05895	COG0446	pyridine nucleotide-disulphide oxidoreductase
MN200_05915	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MN200_05925	COG0280	phosphate acetyltransferase
MN200_05925	COG0281	malic enzyme
MN200_05930	COG1716	ATPase activity
MN200_05930	COG5001	Diguanylate cyclase
MN200_05935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MN200_05940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MN200_05945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MN200_05990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MN200_05995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MN200_06010	COG1671	Belongs to the UPF0178 family
MN200_06025	COG4591	ABC-type transport system involved in lipoprotein release permease component
MN200_06030	COG1136	(ABC) transporter
MN200_06035	COG0658	competence protein
MN200_06035	COG2333	competence protein COMEC
MN200_06055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MN200_06060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MN200_06065	COG0628	permease
MN200_06070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MN200_06100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MN200_06120	COG0823	Involved in the tonB-independent uptake of proteins
MN200_06140	COG0824	Thioesterase
MN200_06145	COG2255	four-way junction helicase activity
MN200_06160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MN200_06160	COG0047	phosphoribosylformylglycinamidine synthase activity
MN200_06180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MN200_06180	COG3323	Protein of unknown function (DUF1653)
MN200_06185	COG0778	Nitroreductase
MN200_06190	COG1024	Enoyl-CoA hydratase
MN200_06195	COG1051	belongs to the nudix hydrolase family
MN200_06195	COG1056	cytidyltransferase-related domain
MN200_06200	COG2353	YceI-like domain
MN200_06205	COG0583	DNA-binding transcription factor activity
MN200_06215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MN200_06230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MN200_06235	COG0602	queuosine metabolic process
MN200_06255	COG0583	DNA-binding transcription factor activity
MN200_06260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MN200_06265	COG4208	sulfate ABC transporter
MN200_06280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MN200_06290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MN200_06310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MN200_06495	COG4383	Mu-like prophage protein gp29
MN200_06530	COG4387	Mu-like prophage protein GP36
MN200_06630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MN200_06665	COG0681	Belongs to the peptidase S26 family
MN200_06675	COG0571	ribonuclease III activity
MN200_06680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MN200_06690	COG1381	Involved in DNA repair and RecF pathway recombination
MN200_06695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MN200_06735	COG0436	Aminotransferase
MN200_06745	COG2199	diguanylate cyclase activity
MN200_06760	COG0556	nucleotide-excision repair
MN200_06790	COG0702	epimerase
MN200_06795	COG1733	regulation of RNA biosynthetic process
MN200_06805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MN200_06810	COG0671	phosphoesterase, PA-phosphatase related
MN200_06815	COG4772	TonB-dependent receptor
MN200_06825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MN200_06830	COG0076	glutamate decarboxylase activity
MN200_06835	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MN200_06840	COG0573	inorganic phosphate transmembrane transporter activity
MN200_06850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MN200_06855	COG0616	signal peptide processing
MN200_06860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MN200_06865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MN200_06870	COG1067	ATP-dependent peptidase activity
MN200_06890	COG0254	rRNA binding
MN200_06910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MN200_06915	COG1966	Carbon starvation protein
MN200_06920	COG2879	small protein
MN200_06925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MN200_06930	COG0714	Associated with various cellular activities
MN200_07000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MN200_07005	COG1823	symporter activity
MN200_07015	COG0612	Peptidase, M16
MN200_07050	COG0352	thiamine-phosphate diphosphorylase activity
MN200_07095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MN200_07100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MN200_07115	COG2353	YceI-like domain
MN200_07120	COG0519	Catalyzes the synthesis of GMP from XMP
MN200_07120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MN200_07130	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_07140	COG4302	ethanolamine ammonia-lyase activity
MN200_07145	COG4303	Ethanolamine ammonia lyase large subunit
MN200_07150	COG0531	amino acid
MN200_07170	COG1454	alcohol dehydrogenase
MN200_07180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MN200_07185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MN200_07190	COG2814	Major facilitator Superfamily
MN200_07195	COG2707	UPF0756 membrane protein
MN200_07215	COG0564	pseudouridine synthase activity
MN200_07220	COG0802	atpase or kinase
MN200_07225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MN200_07235	COG1923	regulation of RNA biosynthetic process
MN200_07240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MN200_07255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MN200_07265	COG1192	Involved in chromosome partitioning
MN200_07270	COG1475	DNA binding
MN200_07275	COG0811	peptide transport
MN200_07285	COG1132	(ABC) transporter
MN200_07290	COG1663	tetraacyldisaccharide 4'-kinase activity
MN200_07310	COG0084	hydrolase, TatD family'
MN200_07345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MN200_07355	COG0590	tRNA wobble adenosine to inosine editing
MN200_07375	COG0776	regulation of translation
MN200_07390	COG2431	L-lysine efflux transmembrane transporter activity
MN200_07405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MN200_07410	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MN200_07430	COG1253	flavin adenine dinucleotide binding
MN200_07455	COG0308	aminopeptidase N
MN200_07465	COG0589	response to stress
MN200_07480	COG2076	Multidrug Resistance protein
MN200_07485	COG1309	transcriptional regulator
MN200_07490	COG3135	benzoate transporter
MN200_07500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MN200_07505	COG0583	DNA-binding transcription factor activity
MN200_07520	COG0183	Belongs to the thiolase family
MN200_07525	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_07545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MN200_07550	COG0824	Thioesterase
MN200_07555	COG1454	alcohol dehydrogenase
MN200_07560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MN200_07580	COG0069	glutamate synthase activity
MN200_07585	COG2197	response regulator
MN200_07590	COG4585	Histidine kinase
MN200_07595	COG2850	peptidyl-arginine hydroxylation
MN200_07605	COG0424	maF-like protein
MN200_07615	COG0126	phosphoglycerate kinase activity
MN200_07630	COG0697	spore germination
MN200_07650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MN200_07660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MN200_07665	COG3781	membrane
MN200_07695	COG0506	proline dehydrogenase activity
MN200_07695	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MN200_07695	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MN200_07705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MN200_07710	COG1027	Aspartate ammonia-lyase
MN200_07720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MN200_07785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MN200_07790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MN200_07795	COG0022	dehydrogenase e1 component
MN200_07800	COG0508	dehydrogenase complex catalyzes the overall conversion of
MN200_07805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MN200_07815	COG1063	alcohol dehydrogenase
MN200_07820	COG4628	conserved protein (DUF2132)
MN200_07845	COG1201	RNA secondary structure unwinding
MN200_08025	COG0596	Alpha beta hydrolase
MN200_08090	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MN200_08110	COG0864	Transcriptional regulator
MN200_08135	COG2814	Major facilitator Superfamily
MN200_08145	COG2199	diguanylate cyclase activity
MN200_08190	COG1960	acyl-CoA dehydrogenase activity
MN200_08195	COG1960	acyl-CoA dehydrogenase activity
MN200_08245	COG0552	protein localization to endoplasmic reticulum
MN200_08250	COG0612	Peptidase, M16
MN200_08275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MN200_08275	COG0517	IMP dehydrogenase activity
MN200_08280	COG0133	tryptophan synthase activity
MN200_08290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MN200_08305	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MN200_08310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MN200_08360	COG0537	adenosine 5'-monophosphoramidase activity
MN200_08385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MN200_08390	COG0776	regulation of translation
MN200_08405	COG1959	2 iron, 2 sulfur cluster binding
MN200_08415	COG0822	iron-sulfur transferase activity
MN200_08420	COG0316	Belongs to the HesB IscA family
MN200_08485	COG2814	Major facilitator Superfamily
MN200_08490	COG0583	DNA-binding transcription factor activity
MN200_08495	COG4948	Mandelate Racemase Muconate Lactonizing
MN200_08500	COG4829	muconolactone delta-isomerase
MN200_08510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MN200_08520	COG0511	ligase activity, forming carbon-carbon bonds
MN200_08535	COG0439	Biotin carboxylase
MN200_08550	COG0583	DNA-binding transcription factor activity
MN200_08555	COG0183	Belongs to the thiolase family
MN200_08565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MN200_08575	COG2233	PERMEase
MN200_08580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MN200_08585	COG0251	oxidation-reduction process
MN200_08590	COG1335	isochorismatase
MN200_08595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MN200_08600	COG0596	Alpha beta hydrolase
MN200_08605	COG0640	Transcriptional regulator
MN200_08625	COG3122	Protein conserved in bacteria
MN200_08630	COG0668	transmembrane transport
MN200_08640	COG1132	(ABC) transporter
MN200_08655	COG2814	Major facilitator Superfamily
MN200_08665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MN200_08670	COG3300	MHYT domain
MN200_08670	COG5001	Diguanylate cyclase
MN200_08680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MN200_08775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MN200_08825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MN200_08830	COG0583	DNA-binding transcription factor activity
MN200_08835	COG1380	Effector of murein hydrolase LrgA
MN200_08840	COG1346	cytolysis
MN200_08855	COG2223	nitrite transmembrane transporter activity
MN200_08885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MN200_08890	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MN200_08895	COG2207	Transcriptional regulator
MN200_08900	COG1944	ATP diphosphatase activity
MN200_08905	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MN200_08925	COG0730	response to heat
MN200_08930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MN200_08965	COG0204	Acyl-transferase
MN200_09005	COG1464	Belongs to the NlpA lipoprotein family
MN200_09010	COG1464	Belongs to the NlpA lipoprotein family
MN200_09015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MN200_09020	COG2011	ABC-type metal ion transport system permease component
MN200_09030	COG0012	GTP binding
MN200_09055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MN200_09070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MN200_09095	COG0386	Belongs to the glutathione peroxidase family
MN200_09100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MN200_09105	COG0436	Aminotransferase
MN200_09125	COG3634	alkyl hydroperoxide reductase activity
MN200_09150	COG2070	2-Nitropropane dioxygenase
MN200_09200	COG1278	Cold shock
MN200_09275	COG1309	transcriptional regulator
MN200_09300	COG0842	Transport permease protein
MN200_09305	COG0842	Transport permease protein
MN200_09310	COG1131	(ABC) transporter
MN200_09335	COG2351	hydroxyisourate hydrolase activity
MN200_09345	COG1686	Belongs to the peptidase S11 family
MN200_09350	COG1252	NADH dehydrogenase
MN200_09355	COG1047	Peptidyl-prolyl cis-trans
MN200_09360	COG1254	Belongs to the acylphosphatase family
MN200_09365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MN200_09365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MN200_09385	COG0318	PFAM AMP-dependent synthetase and ligase
MN200_09390	COG2819	hydrolase of the alpha beta superfamily
MN200_09400	COG0372	Belongs to the citrate synthase family
MN200_09430	COG0542	response to heat
MN200_09435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MN200_09460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MN200_09465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MN200_09475	COG0569	domain protein
MN200_09480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MN200_09500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MN200_09510	COG1585	Membrane protein implicated in regulation of membrane protease activity
MN200_09525	COG1294	oxidase, subunit
MN200_09530	COG4890	Cyd operon protein YbgT
MN200_09550	COG1309	transcriptional regulator
MN200_09555	COG1012	belongs to the aldehyde dehydrogenase family
MN200_09565	COG0579	oxidoreductase
MN200_09580	COG0772	Belongs to the SEDS family
MN200_09595	COG0148	phosphopyruvate hydratase activity
MN200_09615	COG0583	DNA-binding transcription factor activity
MN200_09625	COG2814	Major facilitator Superfamily
MN200_09640	COG0446	pyridine nucleotide-disulphide oxidoreductase
MN200_09640	COG1902	pentaerythritol trinitrate reductase activity
MN200_09650	COG2267	carboxylic ester hydrolase activity
MN200_09660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MN200_09665	COG0702	epimerase
MN200_09705	COG1011	Hydrolase
MN200_09710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MN200_09715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MN200_09720	COG2137	regulation of response to DNA damage stimulus
MN200_09740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MN200_09760	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MN200_09775	COG0575	Belongs to the CDS family
MN200_09780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MN200_09800	COG3852	Histidine kinase
MN200_09820	COG0583	DNA-binding transcription factor activity
MN200_09825	COG0024	Methionine aminopeptidase
MN200_09850	COG1113	amino acid transport
MN200_09860	COG0786	glutamate:sodium symporter activity
MN200_09915	COG0729	surface antigen
MN200_09940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MN200_09955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MN200_09960	COG1960	acyl-CoA dehydrogenase activity
MN200_09995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MN200_10000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MN200_10005	COG2890	protein-(glutamine-N5) methyltransferase activity
MN200_10010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MN200_10025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MN200_10055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MN200_10060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MN200_10065	COG1845	cytochrome c oxidase, subunit III
MN200_10070	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MN200_10090	COG0360	Binds together with S18 to 16S ribosomal RNA
MN200_10105	COG0305	Participates in initiation and elongation during chromosome replication
MN200_10110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MN200_10125	COG1305	Transglutaminase-like
MN200_10135	COG2308	Evidence 4 Homologs of previously reported genes of
MN200_10150	COG0445	tRNA wobble uridine modification
MN200_10180	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MN200_10185	COG0138	bifunctional purine biosynthesis protein purh
MN200_10190	COG0151	Belongs to the GarS family
MN200_10225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MN200_10230	COG2011	ABC-type metal ion transport system permease component
MN200_10270	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MN200_10280	COG4122	O-methyltransferase activity
MN200_10300	COG1137	ATPase activity
MN200_10305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MN200_10315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MN200_10320	COG0517	IMP dehydrogenase activity
MN200_10320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MN200_10335	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MN200_10370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MN200_10380	COG0243	molybdopterin cofactor binding
MN200_10385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MN200_10390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MN200_10395	COG2223	nitrite transmembrane transporter activity
MN200_10405	COG1116	anion transmembrane transporter activity
MN200_10405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MN200_10425	COG1643	Atp-dependent helicase
MN200_10435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MN200_10475	COG0515	serine threonine protein kinase
MN200_10475	COG2815	serine threonine protein kinase
MN200_10505	COG1610	YqeY-like protein
MN200_10510	COG4783	chaperone-mediated protein folding
MN200_10540	COG0167	dihydroorotate dehydrogenase activity
MN200_10565	COG0778	Nitroreductase
MN200_10575	COG0513	Belongs to the DEAD box helicase family
MN200_10580	COG1278	Cold shock
MN200_10595	COG2363	Small membrane protein
MN200_10620	COG2249	NAD(P)H dehydrogenase (quinone) activity
MN200_10625	COG0625	glutathione transferase activity
MN200_10630	COG0659	secondary active sulfate transmembrane transporter activity
MN200_10640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MN200_10670	COG0318	PFAM AMP-dependent synthetase and ligase
MN200_10675	COG1309	transcriptional regulator
MN200_10680	COG1960	acyl-CoA dehydrogenase activity
MN200_10685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MN200_10695	COG4770	biotin carboxylase activity
MN200_10710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MN200_10715	COG2031	fatty acid transporter
MN200_10735	COG0540	Belongs to the ATCase OTCase family
MN200_10760	COG1765	OsmC-like protein
MN200_10770	COG0667	Aldo Keto reductase
MN200_10785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MN200_10800	COG1522	sequence-specific DNA binding
MN200_10805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MN200_10820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MN200_10830	COG0527	aspartate kinase activity
MN200_10840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MN200_10865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MN200_10870	COG2252	PERMEase
MN200_10880	COG0415	Belongs to the DNA photolyase family
MN200_10910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MN200_10915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MN200_10925	COG0693	protein deglycase activity
MN200_10930	COG1960	acyl-CoA dehydrogenase activity
MN200_10935	COG1301	dicarboxylic acid transport
MN200_10945	COG3139	Protein of unknown function (DUF1315)
MN200_10950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MN200_10955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MN200_10965	COG0494	nUDIX hydrolase
MN200_10975	COG0642	Histidine kinase
MN200_10990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MN200_11005	COG1720	tRNA m6t6A37 methyltransferase activity
MN200_11060	COG0826	peptidase U32
MN200_11065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MN200_11070	COG3634	alkyl hydroperoxide reductase activity
MN200_11090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MN200_11150	COG4149	molybdate abc transporter
MN200_11155	COG0725	ABC transporter, periplasmic molybdate-binding protein
MN200_11190	COG0521	Mo-molybdopterin cofactor biosynthetic process
MN200_11190	COG0315	cyclic pyranopterin monophosphate synthase activity
MN200_11195	COG0303	'Molybdopterin
MN200_11205	COG1131	(ABC) transporter
MN200_11210	COG0842	Transport permease protein
MN200_11225	COG2951	lytic endotransglycosylase activity
MN200_11260	COG0052	Belongs to the universal ribosomal protein uS2 family
MN200_11285	COG2175	clavaminate synthase activity
MN200_11300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MN200_11305	COG0842	Transport permease protein
MN200_11340	COG1280	lysine exporter protein (LysE YggA)
MN200_11345	COG1522	sequence-specific DNA binding
MN200_11350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MN200_11360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MN200_11370	COG0019	diaminopimelate decarboxylase activity
MN200_11380	COG1113	amino acid transport
MN200_11385	COG1115	amino acid carrier protein
MN200_11400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MN200_11405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MN200_11410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MN200_11415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MN200_11455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MN200_11460	COG3161	chorismate lyase activity
MN200_11470	COG0174	glutamine synthetase
MN200_11475	COG0512	Glutamine amidotransferase of anthranilate synthase
MN200_11480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MN200_11485	COG0134	indole-3-glycerol-phosphate synthase activity
MN200_11490	COG2909	trisaccharide binding
MN200_11505	COG0318	PFAM AMP-dependent synthetase and ligase
MN200_11510	COG0300	oxidoreductase activity
MN200_11520	COG0302	gtp cyclohydrolase
MN200_11530	COG3706	GGDEF domain
MN200_11545	COG3739	integral membrane protein
MN200_11570	COG1741	Belongs to the pirin family
MN200_11585	COG1309	transcriptional regulator
MN200_11645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MN200_11660	COG2826	transposase and inactivated derivatives, IS30 family
MN200_11700	COG0037	tRNA processing
MN200_11705	COG0741	lytic transglycosylase activity
MN200_11710	COG0501	Belongs to the peptidase M48B family
MN200_11725	COG2239	Acts as a magnesium transporter
MN200_11755	COG1253	flavin adenine dinucleotide binding
MN200_11760	COG2851	Citrate transporter
MN200_11800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MN200_11805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MN200_11830	COG0505	Belongs to the CarA family
MN200_11835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MN200_11875	COG2321	neutral zinc metallopeptidase
MN200_11880	COG2354	Protein conserved in bacteria
MN200_11895	COG2268	Band 7 protein
MN200_11905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MN200_11915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MN200_11930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MN200_11935	COG1053	succinate dehydrogenase
MN200_11940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MN200_11945	COG2009	succinate dehydrogenase
MN200_11970	COG0300	oxidoreductase activity
MN200_11985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MN200_11985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MN200_12010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MN200_12035	COG0564	pseudouridine synthase activity
MN200_12045	COG0358	DNA primase activity
MN200_12060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MN200_12090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MN200_12165	COG0586	Pfam SNARE associated Golgi protein
MN200_12180	COG1280	lysine exporter protein (LysE YggA)
MN200_12200	COG2921	Belongs to the UPF0250 family
MN200_12205	COG0321	lipoyl(octanoyl) transferase activity
MN200_12220	COG0531	amino acid
MN200_12230	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_12240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MN200_12245	COG1648	precorrin-2 dehydrogenase activity
MN200_12245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MN200_12250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MN200_12260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MN200_12270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MN200_12290	COG0671	phosphoesterase, PA-phosphatase related
MN200_12295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MN200_12305	COG1538	Outer membrane efflux protein
MN200_12310	COG0393	Putative heavy-metal-binding
MN200_12325	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_12335	COG0525	valine-tRNA ligase activity
MN200_12365	COG0583	DNA-binding transcription factor activity
MN200_12370	COG1278	Cold shock
MN200_12375	COG1278	Cold shock
MN200_12380	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MN200_12390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MN200_12395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MN200_12400	COG0713	ATP synthesis coupled electron transport
MN200_12410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MN200_12425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MN200_12445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MN200_12455	COG2205	protein histidine kinase activity
MN200_12460	COG0745	RESPONSE REGULATOR receiver
MN200_12475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MN200_12490	COG3335	DDE superfamily endonuclease
MN200_12520	COG0439	Biotin carboxylase
MN200_12525	COG1802	Transcriptional regulator
MN200_12530	COG1652	LysM domain
MN200_12540	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_12555	COG1399	metal-binding, possibly nucleic acid-binding protein
MN200_12560	COG3101	peptidyl-lysine hydroxylation
MN200_12565	COG0009	L-threonylcarbamoyladenylate synthase
MN200_12575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MN200_12580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MN200_12650	COG4106	trans-aconitate 2-methyltransferase activity
MN200_12665	COG0596	Alpha beta hydrolase
MN200_12665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MN200_12665	COG2226	methyltransferase
MN200_12675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MN200_12680	COG2193	ferroxidase activity
MN200_12705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MN200_12710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MN200_12715	COG3115	cell septum assembly
MN200_12720	COG1196	nuclear chromosome segregation
MN200_12730	COG0730	response to heat
MN200_12740	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MN200_12750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MN200_12765	COG2826	transposase and inactivated derivatives, IS30 family
MN200_12770	COG0488	(ABC) transporter
MN200_12795	COG3422	double-strand break repair
MN200_12805	COG2824	Alkylphosphonate utilization operon protein PhnA
MN200_12810	COG3189	MarR family transcriptional regulator
MN200_12830	COG0564	pseudouridine synthase activity
MN200_12835	COG0346	lactoylglutathione lyase activity
MN200_12875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MN200_12905	COG1902	pentaerythritol trinitrate reductase activity
MN200_12910	COG3659	wide pore channel activity
MN200_12920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MN200_12930	COG1970	mechanosensitive ion channel activity
MN200_12935	COG1217	gtp-binding protein TYPA
MN200_12940	COG2233	PERMEase
MN200_12945	COG2813	Specifically methylates the guanine in position
MN200_12950	COG0833	amino acid
MN200_12965	COG0183	Belongs to the thiolase family
MN200_12985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MN200_13000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MN200_13005	COG2207	Transcriptional regulator
MN200_13010	COG0183	Belongs to the thiolase family
MN200_13015	COG1024	Enoyl-CoA hydratase
MN200_13015	COG1250	3-hydroxyacyl-CoA dehydrogenase
MN200_13035	COG1272	protein, Hemolysin III
MN200_13040	COG0477	Major facilitator Superfamily
MN200_13050	COG1408	metallophosphoesterase
MN200_13055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MN200_13065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MN200_13090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MN200_13095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MN200_13105	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MN200_13110	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MN200_13120	COG0625	glutathione transferase activity
MN200_13125	COG2969	positive regulation of protein catabolic process
MN200_13185	COG2199	diguanylate cyclase activity
MN200_13215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MN200_13220	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MN200_13240	COG0450	alkyl hydroperoxide reductase
MN200_13260	COG0285	dihydrofolate synthase activity
MN200_13310	COG4206	TonB-dependent receptor
MN200_13315	COG2096	Adenosyltransferase
MN200_13335	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MN200_13340	COG2315	Protein conserved in bacteria
MN200_13345	COG1113	amino acid transport
MN200_13350	COG0745	RESPONSE REGULATOR receiver
MN200_13355	COG2205	protein histidine kinase activity
MN200_13365	COG1960	acyl-CoA dehydrogenase activity
MN200_13370	COG1960	acyl-CoA dehydrogenase activity
MN200_13375	COG3223	Belongs to the PsiE family
MN200_13405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MN200_13435	COG0463	Glycosyl transferase, family 2
MN200_13455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MN200_13460	COG5002	protein histidine kinase activity
MN200_13470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MN200_13480	COG1704	LemA family
MN200_13490	COG1862	Preprotein translocase
MN200_13515	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MN200_13535	COG1426	Protein conserved in bacteria
MN200_13595	COG0440	acetolactate synthase activity
MN200_13600	COG0028	Belongs to the TPP enzyme family
MN200_13625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MN200_13630	COG1136	(ABC) transporter
MN200_13630	COG0577	efflux transmembrane transporter activity
MN200_13635	COG1538	Outer membrane efflux protein
MN200_13660	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MN200_13665	COG1162	GTPase activity
MN200_13690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MN200_13700	COG3781	membrane
MN200_13705	COG0613	PHP domain protein
MN200_13715	COG2350	Protein conserved in bacteria
MN200_13735	COG1666	GTP binding
MN200_13750	COG1607	acyl-coa hydrolase
MN200_13775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MN200_13810	COG1183	phosphatidylcholine synthase activity
MN200_13815	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MN200_13840	COG0039	L-malate dehydrogenase activity
MN200_13850	COG0739	heme binding
MN200_13850	COG0741	lytic transglycosylase activity
MN200_13850	COG1196	nuclear chromosome segregation
MN200_13855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MN200_13860	COG1702	phosphate starvation-inducible protein PhoH
MN200_13865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MN200_13920	COG1295	ribonuclease BN
MN200_13935	COG0179	Fumarylacetoacetate (FAA) hydrolase
MN200_13965	COG0557	exoribonuclease II activity
MN200_13970	COG2720	vancomycin resistance protein
MN200_13975	COG0339	signal peptide processing
MN200_13980	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MN200_14010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MN200_14015	COG1960	acyl-CoA dehydrogenase activity
MN200_14035	COG2072	flavoprotein involved in K transport
MN200_14040	COG0203	ribosomal protein L17
MN200_14045	COG0202	RNA polymerase activity
MN200_14060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MN200_14085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MN200_14095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MN200_14100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MN200_14150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MN200_14165	COG0088	Forms part of the polypeptide exit tunnel
MN200_14170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MN200_14190	COG0433	COG0433 Predicted ATPase
MN200_14200	COG1959	2 iron, 2 sulfur cluster binding
MN200_14215	COG1301	dicarboxylic acid transport
MN200_14220	COG1946	Acyl-CoA thioesterase
MN200_14225	COG2937	Belongs to the GPAT DAPAT family
MN200_14250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MN200_14255	COG1040	competence protein
MN200_14260	COG0494	nUDIX hydrolase
MN200_14270	COG0598	Magnesium transport protein CorA
MN200_14280	COG2854	intermembrane phospholipid transfer
MN200_14285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MN200_14290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MN200_14295	COG1127	ABC transporter
MN200_14300	COG0513	Belongs to the DEAD box helicase family
MN200_14310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MN200_14320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MN200_14325	COG0408	coproporphyrinogen oxidase activity
MN200_14345	COG1960	acyl-CoA dehydrogenase activity
MN200_14355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MN200_14365	COG0534	Mate efflux family protein
MN200_14375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MN200_14380	COG0254	rRNA binding
MN200_14385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MN200_14400	COG2226	methyltransferase
MN200_14410	COG1192	Involved in chromosome partitioning
MN200_14415	COG0628	permease
MN200_14420	COG2032	superoxide dismutase activity
MN200_14425	COG1289	transmembrane transporter activity
MN200_14430	COG2814	Major facilitator Superfamily
MN200_14450	COG0277	FAD linked oxidase domain protein
MN200_14455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MN200_14460	COG5006	permease, DMT superfamily
MN200_14480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MN200_14485	COG5380	lipid catabolic process
MN200_14500	COG0335	large ribosomal subunit rRNA binding
MN200_14510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MN200_14515	COG0228	four-way junction DNA binding
MN200_14550	COG4969	Belongs to the N-Me-Phe pilin family
MN200_14560	COG0194	GDP metabolic process
MN200_14565	COG1758	RNA polymerase activity
MN200_14570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MN200_14605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MN200_14610	COG1704	LemA family
MN200_14620	COG0493	'glutamate synthase
MN200_14625	COG0069	glutamate synthase activity
MN200_14625	COG0067	glutamate synthase
MN200_14625	COG0070	glutamate synthase
MN200_14675	COG2226	methyltransferase
MN200_14685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MN200_14690	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MN200_14710	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MN200_14725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MN200_14745	COG0488	(ABC) transporter
MN200_14750	COG2873	o-acetylhomoserine
MN200_14755	COG4221	oxidoreductase activity
MN200_14785	COG0427	acetyl-CoA hydrolase
MN200_14820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MN200_14855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MN200_14860	COG0531	amino acid
MN200_14875	COG1278	Cold shock
MN200_14880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MN200_14940	COG0582	viral genome integration into host DNA
MN200_14975	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MN200_14985	COG1335	isochorismatase
MN200_15000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MN200_15015	COG1301	dicarboxylic acid transport
MN200_15020	COG0583	DNA-binding transcription factor activity
MN200_15030	COG0629	single-stranded DNA binding
MN200_15130	COG3174	membrane
MN200_15135	COG2205	protein histidine kinase activity
MN200_15150	COG2132	Multicopper oxidase
MN200_15185	COG0629	single-stranded DNA binding
MN200_15190	COG2814	Major facilitator Superfamily
MN200_15200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MN200_15200	COG0352	thiamine-phosphate diphosphorylase activity
MN200_15200	COG0351	phosphomethylpyrimidine kinase
MN200_15230	COG3706	GGDEF domain
MN200_15240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MN200_15255	COG3162	membrane
MN200_15260	COG2205	protein histidine kinase activity
MN200_15260	COG0784	Response regulator, receiver
MN200_15275	COG0431	NADPH-dependent FMN reductase
MN200_15290	COG1028	Short-chain dehydrogenase reductase Sdr
MN200_15300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MN200_15305	COG0668	transmembrane transport
MN200_15310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MN200_15315	COG1519	Transferase
MN200_15320	COG1902	pentaerythritol trinitrate reductase activity
MN200_15355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MN200_15390	COG0426	domain, Protein
MN200_15390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MN200_15395	COG2119	membrane
MN200_15425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MN200_15435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MN200_15445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MN200_15455	COG0189	ligase activity
MN200_15460	COG0386	Belongs to the glutathione peroxidase family
MN200_15465	COG1846	Transcriptional regulator
MN200_15480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MN200_15490	COG0708	Exodeoxyribonuclease III
MN200_15495	COG1393	Belongs to the ArsC family
MN200_15510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MN200_15605	COG3150	esterase
MN200_15615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MN200_15620	COG2918	glutathione biosynthetic process
MN200_15635	COG2733	membrane
MN200_15640	COG0436	Aminotransferase
MN200_15645	COG0534	Mate efflux family protein
MN200_15715	COG0385	Bile acid
MN200_15720	COG1335	isochorismatase
MN200_15725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MN200_15745	COG4215	(ABC) transporter
MN200_15750	COG4160	amino acid transport
MN200_15775	COG3335	DDE superfamily endonuclease
MN200_15780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MN200_15785	COG2983	Belongs to the UPF0260 family
MN200_15790	COG5487	UPF0391 membrane protein
MN200_15820	COG2818	Glycosylase
MN200_15825	COG1064	alcohol dehydrogenase
MN200_15830	COG0436	Aminotransferase
MN200_15845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MN200_15855	COG0484	heat shock protein binding
MN200_15885	COG2233	PERMEase
MN200_15890	COG0583	DNA-binding transcription factor activity
MN200_15900	COG4774	siderophore transport
MN200_15910	COG0129	dihydroxy-acid dehydratase activity
MN200_15925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MN200_15925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MN200_15970	COG0733	neurotransmitter:sodium symporter activity
MN200_15980	COG2814	Major facilitator Superfamily
MN200_16010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MN200_16015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MN200_16020	COG2951	lytic endotransglycosylase activity
MN200_16025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MN200_16040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MN200_16060	COG0861	Integral membrane protein TerC family
MN200_16070	COG0754	glutathionylspermidine amidase activity
MN200_16080	COG0402	S-adenosylhomocysteine deaminase activity
MN200_16100	COG1230	cation diffusion facilitator family transporter
MN200_16120	COG0706	membrane insertase activity
MN200_16125	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MN200_16155	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MN200_16155	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MN200_16160	COG0697	spore germination
MN200_16165	COG1113	amino acid transport
MN200_16170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MN200_16180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MN200_16210	COG1979	alcohol dehydrogenase
MN200_16225	COG1012	belongs to the aldehyde dehydrogenase family
MN200_16230	COG1902	pentaerythritol trinitrate reductase activity
MN200_16240	COG1309	transcriptional regulator
MN200_16245	COG2130	NADP-dependent
MN200_16265	COG0582	viral genome integration into host DNA
MN200_16280	COG2026	Addiction module toxin, RelE StbE family
MN200_16315	COG4115	mRNA cleavage
MN200_16325	COG3293	Transposase
MN200_16335	COG0210	DNA helicase
MN200_16340	COG1196	nuclear chromosome segregation
MN200_16355	COG1063	alcohol dehydrogenase
MN200_16400	COG1570	exodeoxyribonuclease VII activity
MN200_16415	COG1877	trehalose-phosphatase activity
MN200_16420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MN200_16425	COG2223	nitrite transmembrane transporter activity
MN200_16470	COG2323	membrane
MN200_16490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MN200_16550	COG1192	Involved in chromosome partitioning
MN200_16555	COG1475	DNA binding