locus-tag	class	description
BS636_00005	COG0512	Glutamine amidotransferase of anthranilate synthase
BS636_00055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS636_00070	COG2084	Dehydrogenase
BS636_00075	COG2233	PERMEase
BS636_00080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_00085	COG0251	oxidation-reduction process
BS636_00090	COG1335	isochorismatase
BS636_00095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS636_00100	COG0596	Alpha beta hydrolase
BS636_00110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS636_00120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS636_00160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BS636_00165	COG3161	chorismate lyase activity
BS636_00180	COG0512	Glutamine amidotransferase of anthranilate synthase
BS636_00185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS636_00200	COG0302	gtp cyclohydrolase
BS636_00215	COG3706	GGDEF domain
BS636_00230	COG3739	integral membrane protein
BS636_00245	COG1741	Belongs to the pirin family
BS636_00260	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS636_00260	COG1902	pentaerythritol trinitrate reductase activity
BS636_00270	COG0277	FAD linked oxidase domain protein
BS636_00280	COG2186	Transcriptional regulator
BS636_00285	COG1620	l-lactate permease
BS636_00300	COG5001	Diguanylate cyclase
BS636_00300	COG2203	Gaf domain
BS636_00300	COG3706	GGDEF domain
BS636_00300	COG4251	negative regulation of phosphorylation
BS636_00305	COG0418	dihydroorotase activity
BS636_00310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS636_00320	COG0833	amino acid
BS636_00330	COG0833	amino acid
BS636_00370	COG4172	Belongs to the ABC transporter superfamily
BS636_00375	COG4239	(ABC) transporter, permease
BS636_00380	COG4174	ABC transporter (Permease)
BS636_00385	COG4166	transmembrane transport
BS636_00390	COG0741	lytic transglycosylase activity
BS636_00390	COG1388	LysM domain
BS636_00440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS636_00445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS636_00450	COG2194	sulfuric ester hydrolase activity
BS636_00455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BS636_00465	COG2155	Conserved Protein
BS636_00475	COG0006	proline dipeptidase activity
BS636_00510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS636_00520	COG2234	aminopeptidase activity
BS636_00530	COG3384	dioxygenase
BS636_00540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS636_00545	COG2878	Part of a membrane complex involved in electron transport
BS636_00550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS636_00575	COG0768	penicillin binding
BS636_00580	COG0742	ribosomal rna small subunit methyltransferase
BS636_00605	COG0204	Acyl-transferase
BS636_00650	COG0477	Major facilitator Superfamily
BS636_00665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS636_00685	COG3321	synthase
BS636_00685	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_00685	COG0604	alcohol dehydrogenase
BS636_00695	COG3118	belongs to the thioredoxin family
BS636_00730	COG0175	sulfate reduction
BS636_00745	COG2268	Band 7 protein
BS636_00750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS636_00760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS636_00775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS636_00780	COG1053	succinate dehydrogenase
BS636_00785	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BS636_00790	COG2009	succinate dehydrogenase
BS636_00805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BS636_00805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS636_00820	COG3695	enzyme binding
BS636_00835	COG2321	neutral zinc metallopeptidase
BS636_00840	COG2354	Protein conserved in bacteria
BS636_00860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS636_00865	COG1773	rubredoxin
BS636_00870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS636_00880	COG0583	DNA-binding transcription factor activity
BS636_00890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS636_00900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BS636_00905	COG4181	ATPase activity
BS636_00945	COG0306	phosphate transporter
BS636_00965	COG2376	Dihydroxyacetone kinase
BS636_00970	COG2066	Belongs to the glutaminase family
BS636_00975	COG3706	GGDEF domain
BS636_00980	COG3706	GGDEF domain
BS636_00985	COG0300	oxidoreductase activity
BS636_00995	COG0525	valine-tRNA ligase activity
BS636_01015	COG3338	carbonate dehydratase activity
BS636_01020	COG2323	membrane
BS636_01045	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS636_01060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS636_01065	COG0142	geranyltranstransferase activity
BS636_01070	COG2828	Protein conserved in bacteria
BS636_01075	COG1113	amino acid transport
BS636_01105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BS636_01115	COG1530	ribonuclease E activity
BS636_01120	COG0424	maF-like protein
BS636_01125	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BS636_01130	COG1792	Involved in formation and maintenance of cell shape
BS636_01135	COG1077	Cell shape determining protein MreB Mrl
BS636_01140	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS636_01150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS636_01190	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BS636_01205	COG1294	oxidase, subunit
BS636_01210	COG1271	oxidase subunit
BS636_01230	COG0640	Transcriptional regulator
BS636_01240	COG4106	trans-aconitate 2-methyltransferase activity
BS636_01255	COG2226	methyltransferase
BS636_01255	COG2267	carboxylic ester hydrolase activity
BS636_01260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BS636_01280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS636_01295	COG2814	Major facilitator Superfamily
BS636_01300	COG1024	Enoyl-CoA hydratase
BS636_01305	COG1012	belongs to the aldehyde dehydrogenase family
BS636_01315	COG1960	acyl-CoA dehydrogenase activity
BS636_01330	COG3485	protocatechuate 3,4-dioxygenase
BS636_01335	COG3485	protocatechuate 3,4-dioxygenase
BS636_01340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS636_01345	COG0596	Alpha beta hydrolase
BS636_01350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS636_01355	COG0183	Belongs to the thiolase family
BS636_01360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS636_01365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS636_01370	COG1414	Transcriptional regulator
BS636_01375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS636_01380	COG1414	Transcriptional regulator
BS636_01400	COG1113	amino acid transport
BS636_01405	COG1448	Aminotransferase
BS636_01425	COG0625	glutathione transferase activity
BS636_01440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS636_01445	COG0583	DNA-binding transcription factor activity
BS636_01450	COG0730	response to heat
BS636_01455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_01460	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS636_01490	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS636_01505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS636_01510	COG4206	TonB-dependent receptor
BS636_01520	COG0500	methyltransferase
BS636_01525	COG4771	TonB-dependent receptor
BS636_01570	COG3177	Filamentation induced by cAMP protein fic
BS636_01665	COG0582	viral genome integration into host DNA
BS636_01675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BS636_01680	COG2814	Major facilitator Superfamily
BS636_01685	COG1566	PFAM secretion protein HlyD family protein
BS636_01690	COG2050	protein possibly involved in aromatic compounds catabolism
BS636_01700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS636_01715	COG0420	3'-5' exonuclease activity
BS636_01745	COG0735	belongs to the Fur family
BS636_01750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS636_01755	COG2914	Belongs to the UPF0125 (RnfH) family
BS636_01770	COG0121	glutamine amidotransferase
BS636_01780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS636_01785	COG0756	dUTP diphosphatase activity
BS636_01795	COG2885	chlorophyll binding
BS636_01800	COG0204	Acyl-transferase
BS636_01830	COG0531	amino acid
BS636_01830	COG1674	ftsk spoiiie
BS636_01835	COG0492	ferredoxin-NADP+ reductase activity
BS636_01840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BS636_01850	COG0456	acetyltransferase
BS636_01900	COG1113	amino acid transport
BS636_01905	COG0251	oxidation-reduction process
BS636_01920	COG1522	sequence-specific DNA binding
BS636_01930	COG0579	oxidoreductase
BS636_01940	COG1652	LysM domain
BS636_01945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS636_01950	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_01960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BS636_01965	COG1399	metal-binding, possibly nucleic acid-binding protein
BS636_01970	COG3101	peptidyl-lysine hydroxylation
BS636_01975	COG0009	L-threonylcarbamoyladenylate synthase
BS636_01990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BS636_01995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BS636_02010	COG2193	ferroxidase activity
BS636_02015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS636_02020	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BS636_02025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BS636_02035	COG1196	nuclear chromosome segregation
BS636_02045	COG0730	response to heat
BS636_02050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BS636_02050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BS636_02060	COG3545	Serine hydrolase
BS636_02065	COG3545	Serine hydrolase
BS636_02070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS636_02095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS636_02100	COG2076	Multidrug Resistance protein
BS636_02105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS636_02115	COG4269	membrane
BS636_02120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BS636_02135	COG1968	undecaprenyl-diphosphatase activity
BS636_02140	COG1214	PFAM Peptidase M22, glycoprotease
BS636_02150	COG0494	nUDIX hydrolase
BS636_02165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS636_02190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS636_02195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS636_02205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BS636_02210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BS636_02220	COG2969	positive regulation of protein catabolic process
BS636_02290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BS636_02295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BS636_02310	COG0450	alkyl hydroperoxide reductase
BS636_02325	COG0285	dihydrofolate synthase activity
BS636_02360	COG0133	tryptophan synthase activity
BS636_02370	COG4206	TonB-dependent receptor
BS636_02375	COG2096	Adenosyltransferase
BS636_02395	COG2315	Protein conserved in bacteria
BS636_02410	COG0745	RESPONSE REGULATOR receiver
BS636_02415	COG2205	protein histidine kinase activity
BS636_02425	COG1960	acyl-CoA dehydrogenase activity
BS636_02430	COG1960	acyl-CoA dehydrogenase activity
BS636_02460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BS636_02470	COG1704	LemA family
BS636_02485	COG1862	Preprotein translocase
BS636_02495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS636_02515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS636_02520	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_02560	COG2986	histidine ammonia-lyase
BS636_02585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS636_02590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BS636_02605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS636_02620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS636_02635	COG2084	Dehydrogenase
BS636_02640	COG3622	Belongs to the hyi family
BS636_02655	COG0004	ammonium transporteR
BS636_02660	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BS636_02665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BS636_02670	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BS636_02675	COG2814	Major facilitator Superfamily
BS636_02685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS636_02695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS636_02700	COG2003	Belongs to the UPF0758 family
BS636_02705	COG3781	membrane
BS636_02725	COG2350	Protein conserved in bacteria
BS636_02755	COG1607	acyl-coa hydrolase
BS636_02770	COG3453	Protein conserved in bacteria
BS636_02770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS636_02805	COG2801	Transposase and inactivated derivatives
BS636_02840	COG0726	polysaccharide deacetylase
BS636_02855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BS636_02875	COG1660	Displays ATPase and GTPase activities
BS636_02880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BS636_02890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS636_02895	COG0617	tRNA 3'-terminal CCA addition
BS636_02900	COG1555	photosystem II stabilization
BS636_02905	COG3956	TIGRFAM MazG family protein
BS636_02910	COG4221	oxidoreductase activity
BS636_02925	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS636_02935	COG0124	histidyl-tRNA synthetase
BS636_02945	COG1426	Protein conserved in bacteria
BS636_02965	COG2975	iron-sulfur cluster assembly
BS636_03000	COG0440	acetolactate synthase activity
BS636_03005	COG0028	Belongs to the TPP enzyme family
BS636_03035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS636_03040	COG0577	efflux transmembrane transporter activity
BS636_03040	COG1136	(ABC) transporter
BS636_03045	COG1538	Outer membrane efflux protein
BS636_03055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS636_03065	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BS636_03070	COG1162	GTPase activity
BS636_03090	COG3783	Cytochrome b(562)
BS636_03100	COG0084	hydrolase, TatD family'
BS636_03115	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BS636_03130	COG0793	Belongs to the peptidase S41A family
BS636_03155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS636_03160	COG0857	belongs to the CobB CobQ family
BS636_03160	COG0280	phosphate acetyltransferase
BS636_03175	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BS636_03175	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BS636_03190	COG0740	serine-type endopeptidase activity
BS636_03200	COG4774	siderophore transport
BS636_03215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS636_03225	COG2813	Specifically methylates the guanine in position
BS636_03225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BS636_03275	COG3040	lipid binding
BS636_03280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BS636_03320	COG0788	formyltetrahydrofolate deformylase activity
BS636_03335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BS636_03340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS636_03345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS636_03345	COG4651	solute:proton antiporter activity
BS636_03360	COG0724	RNA recognition motif
BS636_03365	COG0210	DNA helicase
BS636_03370	COG1929	Belongs to the glycerate kinase type-1 family
BS636_03405	COG1560	Kdo2-lipid A biosynthetic process
BS636_03445	COG0252	asparaginase activity
BS636_03470	COG0473	3-isopropylmalate dehydrogenase activity
BS636_03485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BS636_03525	COG1960	acyl-CoA dehydrogenase activity
BS636_03530	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BS636_03550	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS636_03555	COG3384	dioxygenase
BS636_03560	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_03575	COG4638	Rieske (2fe-2S)
BS636_03580	COG0583	DNA-binding transcription factor activity
BS636_03600	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BS636_03605	COG3971	2-oxopent-4-enoate hydratase activity
BS636_03610	COG0546	phosphoglycolate phosphatase activity
BS636_03625	COG1530	ribonuclease E activity
BS636_03660	COG1983	PspC domain protein
BS636_03670	COG0471	metal ion transport
BS636_03690	COG0751	glycine-tRNA ligase activity
BS636_03715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS636_03745	COG0493	'glutamate synthase
BS636_03755	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BS636_03765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS636_03780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BS636_03790	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BS636_03790	COG0644	oxidoreductase
BS636_03800	COG4535	Mg2 and Co2 transporter CorC
BS636_03805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BS636_03825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS636_03835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BS636_03855	COG0789	Transcriptional regulator
BS636_03860	COG2841	Protein conserved in bacteria
BS636_03870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BS636_03880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS636_03885	COG1074	ATP-dependent DNA helicase activity
BS636_03890	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BS636_03925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BS636_03950	COG0745	RESPONSE REGULATOR receiver
BS636_03955	COG2205	protein histidine kinase activity
BS636_03960	COG0427	acetyl-CoA hydrolase
BS636_03970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS636_04000	COG0326	Molecular chaperone. Has ATPase activity
BS636_04015	COG2056	Na+-H+ antiporter family
BS636_04040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BS636_04045	COG0085	RNA polymerase activity
BS636_04055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BS636_04060	COG0081	regulation of translation
BS636_04065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BS636_04115	COG0546	phosphoglycolate phosphatase activity
BS636_04145	COG0824	Thioesterase
BS636_04165	COG0181	hydroxymethylbilane synthase activity
BS636_04175	COG3275	phosphorelay sensor kinase activity
BS636_04195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS636_04220	COG3706	GGDEF domain
BS636_04225	COG1024	Enoyl-CoA hydratase
BS636_04225	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS636_04285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BS636_04320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS636_04325	COG0107	imidazoleglycerol-phosphate synthase activity
BS636_04360	COG3158	transport of potassium into the cell
BS636_04405	COG1335	isochorismatase
BS636_04410	COG0583	DNA-binding transcription factor activity
BS636_04415	COG0450	alkyl hydroperoxide reductase
BS636_04430	COG0629	single-stranded DNA binding
BS636_04435	COG2814	Major facilitator Superfamily
BS636_04445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS636_04455	COG3706	GGDEF domain
BS636_04470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS636_04480	COG3162	membrane
BS636_04485	COG2205	protein histidine kinase activity
BS636_04485	COG0784	Response regulator, receiver
BS636_04500	COG0431	NADPH-dependent FMN reductase
BS636_04510	COG0307	riboflavin synthase, alpha
BS636_04525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS636_04535	COG0668	transmembrane transport
BS636_04540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS636_04545	COG1519	Transferase
BS636_04550	COG1902	pentaerythritol trinitrate reductase activity
BS636_04555	COG0640	Transcriptional regulator
BS636_04580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS636_04605	COG0426	domain, Protein
BS636_04605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_04610	COG2119	membrane
BS636_04620	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS636_04655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS636_04670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS636_04680	COG5285	phytanoyl-CoA dioxygenase
BS636_04685	COG0189	ligase activity
BS636_04705	COG0708	Exodeoxyribonuclease III
BS636_04710	COG1393	Belongs to the ArsC family
BS636_04760	COG2351	hydroxyisourate hydrolase activity
BS636_04765	COG2233	PERMEase
BS636_04770	COG3248	Nucleoside-binding outer membrane protein
BS636_04780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS636_04785	COG4266	Belongs to the allantoicase family
BS636_04800	COG0410	ABC transporter
BS636_04815	COG0559	Belongs to the binding-protein-dependent transport system permease family
BS636_04835	COG3150	esterase
BS636_04845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS636_04850	COG2918	glutathione biosynthetic process
BS636_04865	COG2733	membrane
BS636_04905	COG0753	catalase activity
BS636_04925	COG0560	Phosphoserine phosphatase
BS636_04925	COG3830	Belongs to the UPF0237 family
BS636_04935	COG0385	Bile acid
BS636_04940	COG1335	isochorismatase
BS636_04945	COG2814	Major facilitator Superfamily
BS636_04950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS636_04960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BS636_04965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS636_04970	COG5001	Diguanylate cyclase
BS636_04970	COG3300	MHYT domain
BS636_04975	COG2983	Belongs to the UPF0260 family
BS636_04980	COG5487	UPF0391 membrane protein
BS636_04985	COG0728	peptidoglycan biosynthetic process
BS636_04990	COG3023	N-Acetylmuramoyl-L-alanine amidase
BS636_05000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BS636_05005	COG1309	transcriptional regulator
BS636_05015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BS636_05020	COG0546	phosphoglycolate phosphatase activity
BS636_05025	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_05045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BS636_05045	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BS636_05050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS636_05055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS636_05060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS636_05065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS636_05070	COG1116	anion transmembrane transporter activity
BS636_05075	COG1309	transcriptional regulator
BS636_05085	COG0196	riboflavin kinase activity
BS636_05090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BS636_05100	COG1047	Peptidyl-prolyl cis-trans
BS636_05115	COG2133	pyrroloquinoline quinone binding
BS636_05120	COG4251	negative regulation of phosphorylation
BS636_05120	COG3706	GGDEF domain
BS636_05120	COG5001	Diguanylate cyclase
BS636_05120	COG2203	Gaf domain
BS636_05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS636_05215	COG0488	(ABC) transporter
BS636_05220	COG1063	alcohol dehydrogenase
BS636_05230	COG0187	DNA topoisomerase II activity
BS636_05240	COG0592	DNA-directed DNA polymerase activity
BS636_05245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BS636_05250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BS636_05255	COG0594	ribonuclease P activity
BS636_05260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS636_05265	COG0706	membrane insertase activity
BS636_05275	COG0582	viral genome integration into host DNA
BS636_05325	COG2814	Major facilitator Superfamily
BS636_05365	COG1230	cation diffusion facilitator family transporter
BS636_05370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS636_05385	COG0402	S-adenosylhomocysteine deaminase activity
BS636_05390	COG0861	Integral membrane protein TerC family
BS636_05395	COG2814	Major facilitator Superfamily
BS636_05400	COG2388	GCN5-related N-acetyl-transferase
BS636_05420	COG1063	alcohol dehydrogenase
BS636_05425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS636_05440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS636_05445	COG2951	lytic endotransglycosylase activity
BS636_05450	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BS636_05455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BS636_05495	COG2814	Major facilitator Superfamily
BS636_05500	COG2814	Major facilitator Superfamily
BS636_05515	COG0693	protein deglycase activity
BS636_05525	COG1012	belongs to the aldehyde dehydrogenase family
BS636_05530	COG0733	neurotransmitter:sodium symporter activity
BS636_05540	COG0428	transporter
BS636_05555	COG0129	dihydroxy-acid dehydratase activity
BS636_05565	COG0129	dihydroxy-acid dehydratase activity
BS636_05585	COG0583	DNA-binding transcription factor activity
BS636_05590	COG2233	PERMEase
BS636_05605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS636_05625	COG0783	Belongs to the Dps family
BS636_05640	COG2814	Major facilitator Superfamily
BS636_05645	COG0656	L-ascorbic acid biosynthetic process
BS636_05650	COG0583	DNA-binding transcription factor activity
BS636_05655	COG1064	alcohol dehydrogenase
BS636_05660	COG2818	Glycosylase
BS636_05675	COG1194	a g-specific adenine glycosylase
BS636_05690	COG0545	Peptidyl-prolyl cis-trans isomerase
BS636_05705	COG1596	polysaccharide export
BS636_05715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS636_05730	COG2244	polysaccharide biosynthetic process
BS636_05735	COG1216	Glycosyl transferase, family 2
BS636_05735	COG0463	Glycosyl transferase, family 2
BS636_05745	COG0463	Glycosyl transferase, family 2
BS636_05755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS636_05760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BS636_05785	COG0438	transferase activity, transferring glycosyl groups
BS636_05790	COG0438	transferase activity, transferring glycosyl groups
BS636_05795	COG0438	transferase activity, transferring glycosyl groups
BS636_05800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS636_05810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS636_05820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS636_05835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS636_05840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS636_05845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BS636_05855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS636_05860	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BS636_05955	COG0583	DNA-binding transcription factor activity
BS636_05965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS636_05980	COG2271	Major facilitator Superfamily
BS636_06005	COG1192	Involved in chromosome partitioning
BS636_06020	COG0586	Pfam SNARE associated Golgi protein
BS636_06040	COG0519	Catalyzes the synthesis of GMP from XMP
BS636_06040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BS636_06045	COG3706	GGDEF domain
BS636_06045	COG0745	RESPONSE REGULATOR receiver
BS636_06050	COG3706	GGDEF domain
BS636_06110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS636_06115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS636_06130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS636_06140	COG3585	molybdate ion transport
BS636_06160	COG0534	Mate efflux family protein
BS636_06165	COG0436	Aminotransferase
BS636_06170	COG3501	Rhs element vgr protein
BS636_06175	COG3179	chitinase
BS636_06185	COG2837	iron assimilation
BS636_06195	COG3123	guanosine phosphorylase activity
BS636_06200	COG1683	Conserved Protein
BS636_06205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS636_06210	COG1121	(ABC) transporter
BS636_06260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BS636_06290	COG0386	Belongs to the glutathione peroxidase family
BS636_06295	COG0697	spore germination
BS636_06305	COG0758	DNA mediated transformation
BS636_06325	COG4771	TonB-dependent receptor
BS636_06360	COG2814	Major facilitator Superfamily
BS636_06380	COG0477	Major facilitator Superfamily
BS636_06385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS636_06390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS636_06415	COG1253	flavin adenine dinucleotide binding
BS636_06425	COG2860	membrane
BS636_06430	COG0477	Major facilitator Superfamily
BS636_06440	COG0318	PFAM AMP-dependent synthetase and ligase
BS636_06455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BS636_06475	COG0606	chelatase, subunit chli
BS636_06485	COG0347	Belongs to the P(II) protein family
BS636_06490	COG0004	ammonium transporteR
BS636_06500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS636_06500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS636_06515	COG0586	Pfam SNARE associated Golgi protein
BS636_06535	COG0795	lipopolysaccharide-transporting ATPase activity
BS636_06540	COG0795	lipopolysaccharide-transporting ATPase activity
BS636_06545	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BS636_06550	COG0793	Belongs to the peptidase S41A family
BS636_06560	COG4191	Histidine kinase
BS636_06565	COG2197	response regulator
BS636_06575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS636_06585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS636_06590	COG4974	Belongs to the 'phage' integrase family
BS636_06615	COG0772	Belongs to the SEDS family
BS636_06625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS636_06630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS636_06635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BS636_06640	COG0494	nUDIX hydrolase
BS636_06645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BS636_06655	COG1538	Outer membrane efflux protein
BS636_06660	COG1215	transferase activity, transferring glycosyl groups
BS636_06670	COG1132	(ABC) transporter
BS636_06680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BS636_06690	COG0497	DNA recombination
BS636_06695	COG3123	guanosine phosphorylase activity
BS636_06700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS636_06710	COG0237	dephospho-CoA kinase activity
BS636_06765	COG0779	Required for maturation of 30S ribosomal subunits
BS636_06770	COG0195	Participates in both transcription termination and antitermination
BS636_06775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BS636_06780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BS636_06790	COG2212	antiporter activity
BS636_06795	COG1863	multisubunit Na H antiporter MnhE subunit
BS636_06800	COG0651	ATP synthesis coupled electron transport
BS636_06805	COG1006	Multisubunit Na H antiporter MnhC subunit
BS636_06810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS636_06810	COG2111	Na H antiporter
BS636_06825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BS636_06830	COG4221	oxidoreductase activity
BS636_06840	COG0488	(ABC) transporter
BS636_06880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BS636_06900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS636_06905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS636_06910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS636_06915	COG2226	methyltransferase
BS636_06965	COG0067	glutamate synthase
BS636_06965	COG0069	glutamate synthase activity
BS636_06965	COG0070	glutamate synthase
BS636_06970	COG0493	'glutamate synthase
BS636_06975	COG1704	LemA family
BS636_06995	COG3307	-O-antigen
BS636_07005	COG2906	2 iron, 2 sulfur cluster binding
BS636_07015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS636_07020	COG1758	RNA polymerase activity
BS636_07025	COG0194	GDP metabolic process
BS636_07070	COG0228	four-way junction DNA binding
BS636_07075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BS636_07085	COG0335	large ribosomal subunit rRNA binding
BS636_07090	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BS636_07095	COG5380	lipid catabolic process
BS636_07100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BS636_07120	COG5006	permease, DMT superfamily
BS636_07125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS636_07130	COG0277	FAD linked oxidase domain protein
BS636_07150	COG2814	Major facilitator Superfamily
BS636_07160	COG0628	permease
BS636_07165	COG1192	Involved in chromosome partitioning
BS636_07180	COG2226	methyltransferase
BS636_07195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS636_07200	COG0254	rRNA binding
BS636_07205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BS636_07220	COG0534	Mate efflux family protein
BS636_07230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS636_07245	COG1278	Cold shock
BS636_07250	COG1960	acyl-CoA dehydrogenase activity
BS636_07265	COG0408	coproporphyrinogen oxidase activity
BS636_07270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS636_07295	COG1127	ABC transporter
BS636_07300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BS636_07305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BS636_07310	COG2854	intermembrane phospholipid transfer
BS636_07320	COG0598	Magnesium transport protein CorA
BS636_07330	COG0494	nUDIX hydrolase
BS636_07335	COG1040	competence protein
BS636_07340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS636_07350	COG2937	Belongs to the GPAT DAPAT family
BS636_07355	COG1946	Acyl-CoA thioesterase
BS636_07360	COG1301	dicarboxylic acid transport
BS636_07380	COG1959	2 iron, 2 sulfur cluster binding
BS636_07385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS636_07385	COG1017	nitric oxide dioxygenase activity
BS636_07390	COG0433	COG0433 Predicted ATPase
BS636_07395	COG0626	cystathionine gamma-synthase activity
BS636_07410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BS636_07415	COG0088	Forms part of the polypeptide exit tunnel
BS636_07420	COG0089	rRNA binding
BS636_07430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BS636_07480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BS636_07485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BS636_07495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BS636_07515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BS636_07520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BS636_07525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BS636_07530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BS636_07535	COG0202	RNA polymerase activity
BS636_07540	COG0203	ribosomal protein L17
BS636_07545	COG2072	flavoprotein involved in K transport
BS636_07550	COG1960	acyl-CoA dehydrogenase activity
BS636_07555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BS636_07590	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BS636_07595	COG0339	signal peptide processing
BS636_07605	COG0557	exoribonuclease II activity
BS636_07645	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS636_07655	COG1295	ribonuclease BN
BS636_07720	COG1702	phosphate starvation-inducible protein PhoH
BS636_07725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS636_07730	COG0739	heme binding
BS636_07730	COG0741	lytic transglycosylase activity
BS636_07730	COG1196	nuclear chromosome segregation
BS636_07770	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BS636_07775	COG1183	phosphatidylcholine synthase activity
BS636_07845	COG0438	transferase activity, transferring glycosyl groups
BS636_07865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BS636_07885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS636_07890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS636_07895	COG0318	PFAM AMP-dependent synthetase and ligase
BS636_07920	COG0546	phosphoglycolate phosphatase activity
BS636_07930	COG0625	glutathione transferase activity
BS636_07940	COG1238	metal cluster binding
BS636_07960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BS636_07970	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BS636_07975	COG0072	phenylalanine-tRNA ligase activity
BS636_08010	COG0037	tRNA processing
BS636_08050	COG1764	response to oxidative stress
BS636_08055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS636_08125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BS636_08130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS636_08175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS636_08180	COG1408	metallophosphoesterase
BS636_08190	COG0477	Major facilitator Superfamily
BS636_08195	COG1272	protein, Hemolysin III
BS636_08215	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS636_08215	COG1024	Enoyl-CoA hydratase
BS636_08220	COG0183	Belongs to the thiolase family
BS636_08225	COG2207	Transcriptional regulator
BS636_08235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS636_08250	COG0183	Belongs to the thiolase family
BS636_08260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BS636_08260	COG2885	chlorophyll binding
BS636_08270	COG0833	amino acid
BS636_08280	COG2233	PERMEase
BS636_08310	COG1902	pentaerythritol trinitrate reductase activity
BS636_08340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS636_08390	COG0564	pseudouridine synthase activity
BS636_08405	COG2824	Alkylphosphonate utilization operon protein PhnA
BS636_08420	COG0351	phosphomethylpyrimidine kinase
BS636_08420	COG0352	thiamine-phosphate diphosphorylase activity
BS636_08420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BS636_08445	COG4772	TonB-dependent receptor
BS636_08450	COG0431	NADPH-dependent FMN reductase
BS636_08455	COG0798	PFAM Bile acid sodium symporter
BS636_08460	COG0640	Transcriptional regulator
BS636_08470	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS636_08485	COG0745	RESPONSE REGULATOR receiver
BS636_08490	COG2205	protein histidine kinase activity
BS636_08520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BS636_08535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS636_08545	COG0713	ATP synthesis coupled electron transport
BS636_08550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS636_08580	COG0583	DNA-binding transcription factor activity
BS636_08590	COG1126	abc transporter atp-binding protein
BS636_08595	COG0765	amino acid transport
BS636_08600	COG0765	amino acid transport
BS636_08615	COG0531	amino acid
BS636_08620	COG4303	Ethanolamine ammonia lyase large subunit
BS636_08625	COG4302	ethanolamine ammonia-lyase activity
BS636_08635	COG0668	transmembrane transport
BS636_08640	COG2081	HI0933 family
BS636_08665	COG0004	ammonium transporteR
BS636_08680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS636_08680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS636_08695	COG0489	protein tyrosine kinase activity
BS636_08745	COG0442	prolyl-tRNA aminoacylation
BS636_08755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS636_08780	COG0840	transmembrane signaling receptor activity
BS636_08810	COG2832	Protein of unknown function (DUF454)
BS636_08870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS636_08880	COG1289	transmembrane transporter activity
BS636_08885	COG2814	Major facilitator Superfamily
BS636_08900	COG0786	glutamate:sodium symporter activity
BS636_08905	COG1115	amino acid carrier protein
BS636_08915	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS636_08925	COG1607	acyl-coa hydrolase
BS636_08935	COG2814	Major facilitator Superfamily
BS636_08940	COG0583	DNA-binding transcription factor activity
BS636_08960	COG0523	cobalamin synthesis protein
BS636_08965	COG4681	YaeQ
BS636_08980	COG2203	Gaf domain
BS636_08980	COG4251	negative regulation of phosphorylation
BS636_08980	COG3706	GGDEF domain
BS636_08980	COG5001	Diguanylate cyclase
BS636_09010	COG0242	peptide deformylase activity
BS636_09015	COG0393	Putative heavy-metal-binding
BS636_09020	COG0393	Putative heavy-metal-binding
BS636_09025	COG1538	Outer membrane efflux protein
BS636_09035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS636_09050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BS636_09060	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BS636_09070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS636_09075	COG1648	precorrin-2 dehydrogenase activity
BS636_09075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS636_09080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS636_09090	COG0531	amino acid
BS636_09105	COG0321	lipoyl(octanoyl) transferase activity
BS636_09115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS636_09140	COG0586	Pfam SNARE associated Golgi protein
BS636_09190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS636_09195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BS636_09225	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BS636_09235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BS636_09240	COG0358	DNA primase activity
BS636_09250	COG0564	pseudouridine synthase activity
BS636_09275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS636_09295	COG0110	maltose O-acetyltransferase activity
BS636_09305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS636_09310	COG0505	Belongs to the CarA family
BS636_09335	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BS636_09340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS636_09350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS636_09385	COG1253	flavin adenine dinucleotide binding
BS636_09410	COG2239	Acts as a magnesium transporter
BS636_09425	COG0741	lytic transglycosylase activity
BS636_09425	COG0739	heme binding
BS636_09425	COG1196	nuclear chromosome segregation
BS636_09430	COG0037	tRNA processing
BS636_09440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BS636_09445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS636_09460	COG0583	DNA-binding transcription factor activity
BS636_09465	COG1960	acyl-CoA dehydrogenase activity
BS636_09470	COG2814	Major facilitator Superfamily
BS636_09475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS636_09490	COG0456	acetyltransferase
BS636_09490	COG1214	PFAM Peptidase M22, glycoprotease
BS636_09510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS636_09515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS636_09520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BS636_09530	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BS636_09550	COG1115	amino acid carrier protein
BS636_09555	COG1113	amino acid transport
BS636_09575	COG2267	carboxylic ester hydrolase activity
BS636_09580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BS636_09595	COG1280	lysine exporter protein (LysE YggA)
BS636_09630	COG0842	Transport permease protein
BS636_09635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BS636_09655	COG1671	Belongs to the UPF0178 family
BS636_09670	COG4591	ABC-type transport system involved in lipoprotein release permease component
BS636_09675	COG1136	(ABC) transporter
BS636_09680	COG2333	competence protein COMEC
BS636_09680	COG0658	competence protein
BS636_09700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS636_09705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BS636_09710	COG0628	permease
BS636_09745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS636_09765	COG0823	Involved in the tonB-independent uptake of proteins
BS636_09785	COG0824	Thioesterase
BS636_09800	COG2255	four-way junction helicase activity
BS636_09820	COG0047	phosphoribosylformylglycinamidine synthase activity
BS636_09820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS636_09835	COG0583	DNA-binding transcription factor activity
BS636_09840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS636_09845	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
BS636_09850	COG0778	Nitroreductase
BS636_09855	COG1024	Enoyl-CoA hydratase
BS636_09860	COG1051	belongs to the nudix hydrolase family
BS636_09860	COG1056	cytidyltransferase-related domain
BS636_09865	COG2353	YceI-like domain
BS636_09870	COG0583	DNA-binding transcription factor activity
BS636_09880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS636_09890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BS636_09895	COG0602	queuosine metabolic process
BS636_09910	COG0583	DNA-binding transcription factor activity
BS636_09915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BS636_09920	COG4208	sulfate ABC transporter
BS636_09935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BS636_09940	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BS636_09950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS636_09980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS636_10005	COG0571	ribonuclease III activity
BS636_10010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BS636_10020	COG1381	Involved in DNA repair and RecF pathway recombination
BS636_10025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BS636_10060	COG0024	Methionine aminopeptidase
BS636_10065	COG0052	Belongs to the universal ribosomal protein uS2 family
BS636_10090	COG2951	lytic endotransglycosylase activity
BS636_10105	COG0842	Transport permease protein
BS636_10110	COG1131	(ABC) transporter
BS636_10120	COG4695	Portal protein
BS636_10370	COG0582	viral genome integration into host DNA
BS636_10380	COG1278	Cold shock
BS636_10430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS636_10435	COG2862	Uncharacterized protein family, UPF0114
BS636_10465	COG3634	alkyl hydroperoxide reductase activity
BS636_10470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BS636_10480	COG0789	Transcriptional regulator
BS636_10500	COG4993	Dehydrogenase
BS636_10510	COG1720	tRNA m6t6A37 methyltransferase activity
BS636_10525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BS636_10535	COG0745	RESPONSE REGULATOR receiver
BS636_10540	COG0642	Histidine kinase
BS636_10560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS636_10565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS636_10570	COG3139	Protein of unknown function (DUF1315)
BS636_10575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BS636_10580	COG1301	dicarboxylic acid transport
BS636_10585	COG1960	acyl-CoA dehydrogenase activity
BS636_10590	COG0693	protein deglycase activity
BS636_10605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BS636_10625	COG2252	PERMEase
BS636_10630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BS636_10645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS636_10660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BS636_10665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS636_10690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BS636_10705	COG1047	Peptidyl-prolyl cis-trans
BS636_10710	COG1252	NADH dehydrogenase
BS636_10730	COG2351	hydroxyisourate hydrolase activity
BS636_10755	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BS636_10755	COG2755	lipolytic protein G-D-S-L family
BS636_10760	COG0436	Aminotransferase
BS636_10765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS636_10770	COG0386	Belongs to the glutathione peroxidase family
BS636_10785	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BS636_10805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BS636_10825	COG0012	GTP binding
BS636_10850	COG0204	Acyl-transferase
BS636_10860	COG0582	viral genome integration into host DNA
BS636_10890	COG0154	amidase activity
BS636_10910	COG4638	Rieske (2fe-2S)
BS636_10920	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_10930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_10950	COG0411	ABC transporter
BS636_10955	COG0410	ABC transporter
BS636_10960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS636_10975	COG1846	Transcriptional regulator
BS636_10990	COG1012	belongs to the aldehyde dehydrogenase family
BS636_11010	COG3971	2-oxopent-4-enoate hydratase activity
BS636_11015	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BS636_11020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS636_11040	COG1063	alcohol dehydrogenase
BS636_11050	COG1414	Transcriptional regulator
BS636_11055	COG2271	Major facilitator Superfamily
BS636_11060	COG2814	Major facilitator Superfamily
BS636_11065	COG2072	flavoprotein involved in K transport
BS636_11110	COG2871	sodium ion transport
BS636_11125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BS636_11130	COG0183	Belongs to the thiolase family
BS636_11135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS636_11140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS636_11150	COG4829	muconolactone delta-isomerase
BS636_11155	COG4948	Mandelate Racemase Muconate Lactonizing
BS636_11160	COG0583	DNA-binding transcription factor activity
BS636_11250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BS636_11250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BS636_11255	COG1254	Belongs to the acylphosphatase family
BS636_11285	COG3634	alkyl hydroperoxide reductase activity
BS636_11310	COG0450	alkyl hydroperoxide reductase
BS636_11315	COG1643	Atp-dependent helicase
BS636_11335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS636_11340	COG2707	UPF0756 membrane protein
BS636_11365	COG0802	atpase or kinase
BS636_11370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BS636_11380	COG1923	regulation of RNA biosynthetic process
BS636_11385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS636_11395	COG3178	'Phosphotransferase
BS636_11400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BS636_11410	COG1192	Involved in chromosome partitioning
BS636_11415	COG1475	DNA binding
BS636_11420	COG0811	peptide transport
BS636_11430	COG1132	(ABC) transporter
BS636_11435	COG1663	tetraacyldisaccharide 4'-kinase activity
BS636_11455	COG0084	hydrolase, TatD family'
BS636_11490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BS636_11500	COG0590	tRNA wobble adenosine to inosine editing
BS636_11520	COG0776	regulation of translation
BS636_11540	COG2431	L-lysine efflux transmembrane transporter activity
BS636_11555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BS636_11580	COG1253	flavin adenine dinucleotide binding
BS636_11605	COG0308	aminopeptidase N
BS636_11615	COG0589	response to stress
BS636_11620	COG0589	response to stress
BS636_11630	COG3135	benzoate transporter
BS636_11640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS636_11655	COG0183	Belongs to the thiolase family
BS636_11680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS636_11685	COG0824	Thioesterase
BS636_11690	COG1454	alcohol dehydrogenase
BS636_11695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS636_11700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BS636_11715	COG0069	glutamate synthase activity
BS636_11725	COG2308	Evidence 4 Homologs of previously reported genes of
BS636_11735	COG1305	Transglutaminase-like
BS636_11750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BS636_11755	COG0305	Participates in initiation and elongation during chromosome replication
BS636_11770	COG0360	Binds together with S18 to 16S ribosomal RNA
BS636_11780	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BS636_11785	COG1845	cytochrome c oxidase, subunit III
BS636_11790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BS636_11795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS636_11820	COG4682	membrane
BS636_11825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS636_11840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BS636_11845	COG2890	protein-(glutamine-N5) methyltransferase activity
BS636_11865	COG1309	transcriptional regulator
BS636_11870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS636_11895	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BS636_11900	COG0477	Major facilitator Superfamily
BS636_11905	COG0729	surface antigen
BS636_11930	COG1570	exodeoxyribonuclease VII activity
BS636_11985	COG1114	Component of the transport system for branched-chain amino acids
BS636_11990	COG0024	Methionine aminopeptidase
BS636_12000	COG0583	DNA-binding transcription factor activity
BS636_12005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BS636_12020	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS636_12020	COG1902	pentaerythritol trinitrate reductase activity
BS636_12050	COG0148	phosphopyruvate hydratase activity
BS636_12065	COG0772	Belongs to the SEDS family
BS636_12085	COG4890	Cyd operon protein YbgT
BS636_12090	COG1294	oxidase, subunit
BS636_12135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BS636_12155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS636_12165	COG0133	tryptophan synthase activity
BS636_12170	COG0517	IMP dehydrogenase activity
BS636_12200	COG0612	Peptidase, M16
BS636_12205	COG0552	protein localization to endoplasmic reticulum
BS636_12290	COG1960	acyl-CoA dehydrogenase activity
BS636_12295	COG1960	acyl-CoA dehydrogenase activity
BS636_12360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BS636_12365	COG0730	response to heat
BS636_12370	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BS636_12375	COG2207	Transcriptional regulator
BS636_12380	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS636_12400	COG1525	nuclease
BS636_12465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS636_12470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BS636_12480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BS636_12495	COG2814	Major facilitator Superfamily
BS636_12500	COG0509	glycine decarboxylation via glycine cleavage system
BS636_12515	COG1132	(ABC) transporter
BS636_12520	COG0668	transmembrane transport
BS636_12535	COG3122	Protein conserved in bacteria
BS636_12555	COG0640	Transcriptional regulator
BS636_12560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS636_12570	COG0789	Transcriptional regulator
BS636_12590	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BS636_12595	COG0830	nickel cation binding
BS636_12605	COG0829	nickel cation binding
BS636_12620	COG0804	urea catabolic process
BS636_12630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS636_12635	COG0318	PFAM AMP-dependent synthetase and ligase
BS636_12640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS636_12640	COG1017	nitric oxide dioxygenase activity
BS636_12655	COG1960	acyl-CoA dehydrogenase activity
BS636_12660	COG0183	Belongs to the thiolase family
BS636_12665	COG0427	acetyl-CoA hydrolase
BS636_12670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS636_12675	COG0583	DNA-binding transcription factor activity
BS636_12690	COG0439	Biotin carboxylase
BS636_12700	COG2885	chlorophyll binding
BS636_12705	COG0864	Transcriptional regulator
BS636_12715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS636_12740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS636_12745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS636_12750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS636_12750	COG1116	anion transmembrane transporter activity
BS636_12760	COG2223	nitrite transmembrane transporter activity
BS636_12765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS636_12770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS636_12775	COG0243	molybdopterin cofactor binding
BS636_12785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS636_12800	COG0315	cyclic pyranopterin monophosphate synthase activity
BS636_12800	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS636_12805	COG0303	'Molybdopterin
BS636_12810	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS636_12815	COG4149	molybdate abc transporter
BS636_12820	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BS636_12825	COG2223	nitrite transmembrane transporter activity
BS636_12835	COG0347	Belongs to the P(II) protein family
BS636_12850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BS636_12855	COG1309	transcriptional regulator
BS636_12860	COG1012	belongs to the aldehyde dehydrogenase family
BS636_12875	COG1944	ATP diphosphatase activity
BS636_12890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BS636_12905	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BS636_12910	COG1877	trehalose-phosphatase activity
BS636_12925	COG0583	DNA-binding transcription factor activity
BS636_12960	COG0402	S-adenosylhomocysteine deaminase activity
BS636_12970	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BS636_12975	COG2116	formate transmembrane transporter activity
BS636_13005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS636_13010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_13015	COG0583	DNA-binding transcription factor activity
BS636_13045	COG0583	DNA-binding transcription factor activity
BS636_13070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS636_13075	COG0573	inorganic phosphate transmembrane transporter activity
BS636_13085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS636_13090	COG2203	Gaf domain
BS636_13090	COG2199	diguanylate cyclase activity
BS636_13105	COG2072	flavoprotein involved in K transport
BS636_13120	COG1309	transcriptional regulator
BS636_13140	COG1116	anion transmembrane transporter activity
BS636_13145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS636_13150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS636_13155	COG0805	protein transport
BS636_13170	COG3604	Transcriptional regulator
BS636_13185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS636_13195	COG2144	transferase activity, transferring acyl groups
BS636_13205	COG2072	flavoprotein involved in K transport
BS636_13210	COG2801	Transposase and inactivated derivatives
BS636_13300	COG0596	Alpha beta hydrolase
BS636_13335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS636_13340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BS636_13365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS636_13380	COG0439	Biotin carboxylase
BS636_13390	COG3706	GGDEF domain
BS636_13400	COG2814	Major facilitator Superfamily
BS636_13560	COG5410	chromosome segregation
BS636_13580	COG1598	PFAM Uncharacterised protein family UPF0150
BS636_13705	COG0582	viral genome integration into host DNA
BS636_13755	COG1546	Belongs to the CinA family
BS636_13755	COG1058	Belongs to the CinA family
BS636_13765	COG0372	Belongs to the citrate synthase family
BS636_13785	COG0477	Major facilitator Superfamily
BS636_13800	COG0542	response to heat
BS636_13805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BS636_13825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS636_13835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BS636_13840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS636_13845	COG0569	domain protein
BS636_13850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS636_13870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS636_13880	COG1585	Membrane protein implicated in regulation of membrane protease activity
BS636_13900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS636_13905	COG0776	regulation of translation
BS636_13930	COG0822	iron-sulfur transferase activity
BS636_13935	COG0316	Belongs to the HesB IscA family
BS636_13965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS636_13975	COG1027	Aspartate ammonia-lyase
BS636_13985	COG1522	sequence-specific DNA binding
BS636_13990	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BS636_13990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BS636_13990	COG0506	proline dehydrogenase activity
BS636_14010	COG3781	membrane
BS636_14030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS636_14035	COG2011	ABC-type metal ion transport system permease component
BS636_14070	COG0697	spore germination
BS636_14085	COG0126	phosphoglycerate kinase activity
BS636_14095	COG0424	maF-like protein
BS636_14105	COG2850	peptidyl-arginine hydroxylation
BS636_14115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BS636_14120	COG0702	epimerase
BS636_14125	COG0268	Binds directly to 16S ribosomal RNA
BS636_14135	COG1218	3'(2'),5'-bisphosphate nucleotidase
BS636_14140	COG1011	Hydrolase
BS636_14145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS636_14150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BS636_14155	COG2137	regulation of response to DNA damage stimulus
BS636_14170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BS636_14175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BS636_14180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BS636_14190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BS636_14205	COG0575	Belongs to the CDS family
BS636_14210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BS636_14230	COG3852	Histidine kinase
BS636_14235	COG2204	response regulator
BS636_14245	COG0445	tRNA wobble uridine modification
BS636_14275	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BS636_14280	COG0138	bifunctional purine biosynthesis protein purh
BS636_14285	COG0151	Belongs to the GarS family
BS636_14295	COG1464	Belongs to the NlpA lipoprotein family
BS636_14300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS636_14305	COG2011	ABC-type metal ion transport system permease component
BS636_14335	COG2203	Gaf domain
BS636_14335	COG5001	Diguanylate cyclase
BS636_14335	COG3706	GGDEF domain
BS636_14335	COG4251	negative regulation of phosphorylation
BS636_14345	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BS636_14360	COG0589	response to stress
BS636_14385	COG1538	Outer membrane efflux protein
BS636_14390	COG1137	ATPase activity
BS636_14395	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BS636_14405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BS636_14410	COG0517	IMP dehydrogenase activity
BS636_14410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BS636_14450	COG1028	Short-chain dehydrogenase reductase Sdr
BS636_14470	COG0505	Belongs to the CarA family
BS636_14475	COG2353	YceI-like domain
BS636_14480	COG0456	acetyltransferase
BS636_14490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BS636_14495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BS636_14510	COG2391	methyltransferase activity
BS636_14570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS636_14570	COG1017	nitric oxide dioxygenase activity
BS636_14575	COG1309	transcriptional regulator
BS636_14620	COG0352	thiamine-phosphate diphosphorylase activity
BS636_14635	COG3025	triphosphatase activity
BS636_14660	COG0612	Peptidase, M16
BS636_14670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_14675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS636_14725	COG0515	serine threonine protein kinase
BS636_14725	COG2815	serine threonine protein kinase
BS636_14750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BS636_14765	COG4783	chaperone-mediated protein folding
BS636_14820	COG0778	Nitroreductase
BS636_14830	COG0513	Belongs to the DEAD box helicase family
BS636_14835	COG1278	Cold shock
BS636_14850	COG2363	Small membrane protein
BS636_14870	COG2249	NAD(P)H dehydrogenase (quinone) activity
BS636_14880	COG0659	secondary active sulfate transmembrane transporter activity
BS636_14885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BS636_14905	COG2885	chlorophyll binding
BS636_14905	COG3047	cAMP biosynthetic process
BS636_14915	COG0540	Belongs to the ATCase OTCase family
BS636_14935	COG0667	Aldo Keto reductase
BS636_14945	COG1765	OsmC-like protein
BS636_14950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS636_14975	COG1136	(ABC) transporter
BS636_14980	COG4591	ABC-type transport system involved in lipoprotein release permease component
BS636_14990	COG0281	malic enzyme
BS636_15010	COG0714	Associated with various cellular activities
BS636_15015	COG2879	small protein
BS636_15020	COG1966	Carbon starvation protein
BS636_15025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BS636_15065	COG1067	ATP-dependent peptidase activity
BS636_15070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BS636_15075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS636_15080	COG0583	DNA-binding transcription factor activity
BS636_15105	COG1686	Belongs to the peptidase S11 family
BS636_15110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS636_15145	COG0482	sulfurtransferase activity
BS636_15150	COG2915	High frequency lysogenization protein hflD homolog
BS636_15185	COG0616	signal peptide processing
BS636_15190	COG0076	glutamate decarboxylase activity
BS636_15195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS636_15205	COG0671	phosphoesterase, PA-phosphatase related
BS636_15210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS636_15220	COG2814	Major facilitator Superfamily
BS636_15230	COG1733	regulation of RNA biosynthetic process
BS636_15255	COG0556	nucleotide-excision repair
BS636_15285	COG2175	clavaminate synthase activity
BS636_15295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS636_15300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS636_15315	COG2084	Dehydrogenase
BS636_15320	COG2233	PERMEase
BS636_15325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS636_15330	COG0251	oxidation-reduction process
BS636_15335	COG1335	isochorismatase
BS636_15340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS636_15345	COG0596	Alpha beta hydrolase
BS636_15355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS636_15365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS636_15445	COG0583	DNA-binding transcription factor activity
BS636_15455	COG1960	acyl-CoA dehydrogenase activity
BS636_15460	COG2814	Major facilitator Superfamily
BS636_15465	COG1960	acyl-CoA dehydrogenase activity
BS636_15475	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS636_15475	COG1024	Enoyl-CoA hydratase
BS636_15480	COG1607	acyl-coa hydrolase
BS636_15485	COG0183	Belongs to the thiolase family
BS636_15495	COG1464	Belongs to the NlpA lipoprotein family
BS636_15505	COG1464	Belongs to the NlpA lipoprotein family
BS636_15510	COG2011	ABC-type metal ion transport system permease component
BS636_15515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS636_15520	COG0583	DNA-binding transcription factor activity
BS636_15525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS636_15530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS636_15550	COG4585	Histidine kinase
BS636_15580	COG2197	response regulator
BS636_15600	COG2801	Transposase and inactivated derivatives
BS636_15630	COG1518	maintenance of DNA repeat elements
BS636_15655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS636_15660	COG2271	Major facilitator Superfamily
BS636_15670	COG0251	oxidation-reduction process
BS636_15675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS636_15685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS636_15690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS636_15695	COG1012	belongs to the aldehyde dehydrogenase family
BS636_15700	COG0277	FAD linked oxidase domain protein
BS636_15710	COG0582	viral genome integration into host DNA
BS636_15725	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BS636_15740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS636_15745	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS636_15750	COG1024	Enoyl-CoA hydratase
BS636_15755	COG1960	acyl-CoA dehydrogenase activity
BS636_15760	COG0427	acetyl-CoA hydrolase
BS636_15765	COG0183	Belongs to the thiolase family
BS636_15770	COG2814	Major facilitator Superfamily
BS636_15775	COG3385	transposase activity
BS636_15780	COG0583	DNA-binding transcription factor activity
BS636_15785	COG1960	acyl-CoA dehydrogenase activity
BS636_15790	COG2301	Belongs to the HpcH HpaI aldolase family
BS636_15795	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BS636_15800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS636_15805	COG0644	oxidoreductase
BS636_15805	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BS636_15830	COG2026	Addiction module toxin, RelE StbE family
BS636_15835	COG0069	glutamate synthase activity
BS636_15840	COG2218	PFAM glutamate synthase alpha subunit domain protein
BS636_15845	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS636_15855	COG1396	sequence-specific DNA binding
BS636_15860	COG0004	ammonium transporteR
BS636_15870	COG2801	Transposase and inactivated derivatives
BS636_15895	COG3657	addiction module killer protein
BS636_15900	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS636_15905	COG1335	isochorismatase
BS636_15910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS636_15935	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BS636_15960	COG0446	pyridine nucleotide-disulphide oxidoreductase
BS636_15960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BS636_15975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS636_15990	COG2076	Multidrug Resistance protein
BS636_16015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS636_16035	COG2197	response regulator
BS636_16040	COG3850	Histidine kinase
BS636_16045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BS636_16050	COG1475	DNA binding
BS636_16055	COG1192	Involved in chromosome partitioning
BS636_16065	COG0644	oxidoreductase
BS636_16065	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BS636_16070	COG0583	DNA-binding transcription factor activity
BS636_16080	COG1960	acyl-CoA dehydrogenase activity
BS636_16085	COG2814	Major facilitator Superfamily
BS636_16090	COG1960	acyl-CoA dehydrogenase activity
BS636_16100	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS636_16100	COG1024	Enoyl-CoA hydratase
BS636_16105	COG1607	acyl-coa hydrolase
BS636_16110	COG0183	Belongs to the thiolase family
BS636_16120	COG1464	Belongs to the NlpA lipoprotein family
BS636_16145	COG1464	Belongs to the NlpA lipoprotein family
BS636_16165	COG0583	DNA-binding transcription factor activity
