locus-tag	class	description
HGD77_00005	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HGD77_00010	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HGD77_00025	ENOG4105CEN	a g-specific adenine glycosylase
HGD77_00030	ENOG4105FAA	peptidase M23
HGD77_00040	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HGD77_00045	ENOG4105DQ4	alcohol dehydrogenase
HGD77_00050	ENOG4105D7V	transposase
HGD77_00065	ENOG4105E5H	Transposase
HGD77_00105	ENOG4105D7V	transposase
HGD77_00145	ENOG4105C2W	permease
HGD77_00165	ENOG4105D7V	transposase
HGD77_00170	ENOG4105C01	Dihydroxy-acid dehydratase
HGD77_00175	ENOG4105C01	Dihydroxy-acid dehydratase
HGD77_00185	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HGD77_00190	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
HGD77_00200	ENOG4105C8J	)-transporter
HGD77_00215	ENOG4107RKG	DJ-1/PfpI family
HGD77_00225	ENOG4108U3J	
HGD77_00230	ENOG4105D2S	major facilitator superfamily
HGD77_00245	ENOG4105D2S	major facilitator superfamily
HGD77_00275	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HGD77_00305	ENOG4108HWY	Beta-lactamase
HGD77_00325	ENOG4108821	RND type efflux pump
HGD77_00330	ENOG4108821	RND type efflux pump
HGD77_00335	ENOG4108821	RND type efflux pump
HGD77_00340	ENOG4105C5H	ABC transporter
HGD77_00345	ENOG4105E2A	Dehydrogenase
HGD77_00350	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HGD77_00360	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HGD77_00365	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HGD77_00375	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HGD77_00380	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HGD77_00385	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGD77_00395	ENOG4105VNT	transposase (IS4 family) protein
HGD77_00400	ENOG4108PCX	Major Facilitator
HGD77_00415	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HGD77_00420	ENOG4107QUY	Guanine deaminase
HGD77_00430	ENOG4105DU1	integral membrane protein, terc
HGD77_00440	ENOG410830R	acetyltransferase
HGD77_00465	ENOG4105DFU	Cell wall formation (By similarity)
HGD77_00480	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HGD77_00485	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HGD77_00490	ENOG4105CVE	Lytic murein transglycosylase
HGD77_00495	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HGD77_00500	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HGD77_00550	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HGD77_00555	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HGD77_00560	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HGD77_00565	ENOG4105DTN	riboflavin biosynthesis protein ribF
HGD77_00575	ENOG4108R86	Transcriptional regulator
HGD77_00580	ENOG4108VM9	ABC, transporter
HGD77_00585	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HGD77_00590	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HGD77_00595	ENOG4105GVF	(ABC) transporter
HGD77_00600	ENOG4105GVF	(ABC) transporter
HGD77_00605	ENOG4107QZM	n-acetylglutamate synthase
HGD77_00630	ENOG4105UBK	short-chain dehydrogenase reductase
HGD77_00635	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HGD77_00640	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HGD77_00645	ENOG4108Z33	Thiol disulfide Interchange Protein
HGD77_00655	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HGD77_00665	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HGD77_00670	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HGD77_00675	ENOG4105CJR	Integral membrane protein (MviN
HGD77_00685	ENOG4108ZZ3	UPF0260 protein
HGD77_00690	ENOG4105BZU	Histidine kinase
HGD77_00695	ENOG4105D1H	recombination factor protein RarA
HGD77_00700	ENOG4105C8V	SAICAR synthetase
HGD77_00710	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HGD77_00715	ENOG4108SC4	)-transporter
HGD77_00720	ENOG4108RWI	nicotinamidase
HGD77_00725	ENOG4105C09	Bile acid
HGD77_00780	ENOG4105KHC	sulfurtransferase
HGD77_00805	ENOG4106BRA	Membrane
HGD77_00820	ENOG4105D9M	gamma-glutamylcysteine synthetase
HGD77_00825	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HGD77_00840	ENOG4105IPS	esterase
HGD77_00845	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HGD77_00850	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HGD77_00855	ENOG4105C32	Amino acid ABC transporter (Permease)
HGD77_00865	ENOG4105C0Z	ABC transporter
HGD77_00870	ENOG4108IV0	ABC, transporter
HGD77_00890	ENOG4108Z7F	N-acetyltransferase
HGD77_00915	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HGD77_00920	ENOG4105BZU	Histidine kinase
HGD77_00945	ENOG4105CGK	Exodeoxyribonuclease III
HGD77_00950	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HGD77_00955	ENOG4105VEQ	Cold shock protein
HGD77_00970	ENOG4105E3B	Multicopper oxidase
HGD77_00985	ENOG4105D7Z	glutathione synthase
HGD77_01000	ENOG4105DFU	Cell wall formation (By similarity)
HGD77_01010	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HGD77_01015	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HGD77_01020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HGD77_01040	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HGD77_01045	ENOG4107QSN	dihydrolipoamide acetyltransferase
HGD77_01065	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HGD77_01080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HGD77_01105	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HGD77_01110	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HGD77_01120	ENOG4105D64	Mechanosensitive ion channel
HGD77_01125	ENOG4105KAF	membrAne
HGD77_01130	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HGD77_01135	ENOG4107T8P	acyl-Coa dehydrogenase
HGD77_01140	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HGD77_01145	ENOG4105FBW	Monooxygenase
HGD77_01150	ENOG4108UZX	fmn reductase
HGD77_01165	ENOG4105BZU	Histidine kinase
HGD77_01170	ENOG41062QD	Membrane
HGD77_01195	ENOG4105C94	Transporter
HGD77_01205	ENOG4105BZU	Histidine kinase
HGD77_01215	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HGD77_01225	ENOG4105DWF	phosphomethylpyrimidine kinase
HGD77_01235	ENOG4107RDB	Major Facilitator
HGD77_01240	ENOG4108UUM	single-stranded DNA-binding protein
HGD77_01245	ENOG4108FPN	Integrase
HGD77_01270	ENOG4105C4X	radical SAM domain protein
HGD77_01315	ENOG4105D3R	alkyl hydroperoxide reductase
HGD77_01320	ENOG4108QDE	fad dependent oxidoreductase
HGD77_01405	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HGD77_01445	ENOG4105CUV	Homoserine Kinase
HGD77_01490	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HGD77_01560	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HGD77_01570	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
HGD77_01585	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HGD77_01615	ENOG4108NEV	two component transcriptional regulator, LytTR family
HGD77_01620	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HGD77_01660	ENOG4105GVR	general secretion pathway protein D
HGD77_01670	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HGD77_01700	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HGD77_01710	ENOG4105PM1	preprotein translocase subunit SecE
HGD77_01715	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HGD77_01725	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HGD77_01730	ENOG4108VZM	50s ribosomal protein L10
HGD77_01735	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HGD77_01740	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HGD77_01745	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HGD77_01765	ENOG4105D3Y	Na H antiporter
HGD77_01770	ENOG4105EIF	outer membrane protein W
HGD77_01780	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HGD77_01815	ENOG4107ZXU	DSBA oxidoreductase
HGD77_01820	ENOG4105CYC	Transferase
HGD77_01825	ENOG4105E0F	Histidine kinase
HGD77_01855	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HGD77_01875	ENOG4105CSR	polyphosphate kinase 2
HGD77_01885	ENOG4105DSY	exodeoxyribonuclease V, gamma
HGD77_01890	ENOG4107QKA	exodeoxyribonuclease V beta
HGD77_01895	ENOG4107QYX	exodeoxyribonuclease v alpha
HGD77_01905	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HGD77_01910	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HGD77_01915	ENOG4105Z2P	Protein of unknown function (DUF465)
HGD77_01920	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HGD77_01930	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HGD77_01935	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HGD77_01940	ENOG4105C25	Primosomal protein n'
HGD77_01945	ENOG4105D7Q	type ii secretion system
HGD77_01950	ENOG4108VAU	general secretion pathway protein G
HGD77_01960	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HGD77_01965	ENOG4108JU5	Magnesium and cobalt efflux protein
HGD77_01970	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HGD77_01975	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HGD77_01985	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HGD77_02000	ENOG4105C5X	domain protein
HGD77_02010	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HGD77_02020	ENOG4105BZ8	glutamate synthase
HGD77_02045	ENOG4105C5I	Dehydrogenase
HGD77_02065	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HGD77_02095	ENOG4105C8P	)-transporter
HGD77_02110	ENOG41067S9	phage shock protein C, PspC
HGD77_02135	ENOG4105J5T	Amp-dependent synthetase and ligase
HGD77_02140	ENOG4105C03	ribonuclease
HGD77_02145	ENOG4105EI2	Pseudouridine synthase
HGD77_02150	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HGD77_02155	ENOG4105F9F	transposase
HGD77_02160	ENOG4105IKQ	hydratase
HGD77_02165	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
HGD77_02170	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
HGD77_02185	ENOG4105EPF	Outer membrane porin
HGD77_02195	ENOG4108W5M	transcriptional regulator
HGD77_02210	ENOG4105FUY	alpha subunit
HGD77_02225	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
HGD77_02230	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
HGD77_02235	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HGD77_02255	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HGD77_02260	ENOG4105CH6	catalase
HGD77_02275	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HGD77_02310	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HGD77_02325	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HGD77_02385	ENOG4105D1S	lipid A biosynthesis
HGD77_02390	ENOG4105C5H	ABC transporter
HGD77_02410	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HGD77_02430	ENOG4105BZW	Glycerate kinase
HGD77_02435	ENOG4105C4R	Atp-dependent dna helicase
HGD77_02455	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HGD77_02470	ENOG4107RGH	Aldehyde dehydrogenase
HGD77_02475	ENOG41062JF	Transcriptional regulator
HGD77_02480	ENOG4105CIY	formyltetrahydrofolate deformylase
HGD77_02525	ENOG4105QNF	Outer membrane lipoprotein
HGD77_02590	ENOG4105DWV	Homoserine O-trans-acetylase
HGD77_02595	ENOG4105DWV	Homoserine O-trans-acetylase
HGD77_02600	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HGD77_02610	ENOG4108ESX	Receptor
HGD77_02615	ENOG4105D05	Receptor
HGD77_02625	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HGD77_02640	ENOG4107GFK	fumarate
HGD77_02650	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HGD77_02655	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HGD77_02680	ENOG4105CN1	protease
HGD77_02685	ENOG4105BZU	Histidine kinase
HGD77_02690	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HGD77_02705	ENOG4105F8V	Hydrolase, tatD family
HGD77_02710	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HGD77_02720	ENOG4105VW4	glutaredoxin 3
HGD77_02730	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HGD77_02735	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HGD77_02745	ENOG4105CUZ	uba thif-type nad fad binding protein
HGD77_02755	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HGD77_02760	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HGD77_02765	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HGD77_02790	ENOG4105C7K	acetolactate synthase
HGD77_02795	ENOG4108ZP8	Acetolactate synthase small subunit
HGD77_02800	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HGD77_02830	ENOG4105F9F	transposase
HGD77_02860	ENOG4105F9F	transposase
HGD77_02875	ENOG4105F9F	transposase
HGD77_02895	ENOG4105WVQ	Fe-S assembly protein IscX
HGD77_02915	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HGD77_02935	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HGD77_02955	ENOG4105DXN	mazG family
HGD77_02960	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HGD77_02965	ENOG4105DJ0	Poly(A) Polymerase
HGD77_02970	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGD77_02985	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HGD77_02990	ENOG41080Z8	PHOSPHOCARRIER protein
HGD77_03000	ENOG4105BZU	Histidine kinase
HGD77_03005	ENOG4105D7V	transposase
HGD77_03010	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HGD77_03015	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HGD77_03065	ENOG4105C9M	aspartyl-trna synthetase
HGD77_03075	ENOG4105UGU	tonB-dependent Receptor
HGD77_03095	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HGD77_03105	ENOG4105CSU	acyl-Coa dehydrogenase
HGD77_03110	ENOG4105CSU	acyl-Coa dehydrogenase
HGD77_03120	ENOG4105EB3	Histidine kinase
HGD77_03125	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HGD77_03135	ENOG4105CNG	UPF0061 protein
HGD77_03150	ENOG4108WBT	adenosyltransferase
HGD77_03155	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HGD77_03170	ENOG4105CEY	Amp-dependent synthetase and ligase
HGD77_03190	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HGD77_03205	ENOG4105CYM	Glutathione S-transferase
HGD77_03215	ENOG4105W39	Membrane
HGD77_03245	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HGD77_03260	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HGD77_03270	ENOG4105C9X	ppx gppa phosphatase
HGD77_03280	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HGD77_03285	ENOG4105II7	pyrroline-5-carboxylate reductase
HGD77_03290	ENOG4108VIA	integral membrane protein
HGD77_03300	ENOG4105C2M	dna polymerase I
HGD77_03320	ENOG4107QHF	type ii secretion system protein e
HGD77_03345	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HGD77_03415	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HGD77_03420	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HGD77_03470	ENOG4105P8F	nudix hydrolase
HGD77_03480	ENOG41072GX	Peptidase M22 Glycoprotease
HGD77_03485	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HGD77_03505	ENOG4108M3P	Membrane
HGD77_03520	ENOG4105DJV	ribulose-phosphate 3-epimerase
HGD77_03530	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HGD77_03545	ENOG4105DNH	Major Facilitator
HGD77_03550	ENOG4105DXM	phenylacetic acid degradation protein
HGD77_03555	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HGD77_03560	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HGD77_03565	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HGD77_03570	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HGD77_03575	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HGD77_03580	ENOG4105E39	Enoyl-CoA hydratase
HGD77_03585	ENOG4108UKI	Enoyl-CoA hydratase
HGD77_03590	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HGD77_03595	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_03600	ENOG4105DZS	Phenylacetate-CoA ligase
HGD77_03605	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
HGD77_03610	ENOG4108Z0R	Transferase
HGD77_03615	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HGD77_03625	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGD77_03650	ENOG4105HF0	Membrane
HGD77_03660	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HGD77_03670	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HGD77_03680	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HGD77_03685	ENOG4108UWD	Iron-storage protein
HGD77_03750	ENOG4105FE9	pseudouridine synthase
HGD77_03755	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HGD77_03760	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HGD77_03775	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HGD77_03780	ENOG4108BPE	-transporting atpase
HGD77_03785	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HGD77_03795	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HGD77_03800	ENOG4105CHR	reductase
HGD77_03805	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HGD77_03810	ENOG4109066	lysm domain bon superfamily protein
HGD77_03815	ENOG4105EW9	transcriptional regulator AsnC family
HGD77_03830	ENOG4105M4H	endoribonuclease L-psp
HGD77_03840	ENOG4108YXA	Membrane
HGD77_03855	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HGD77_03870	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HGD77_03880	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HGD77_03890	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HGD77_03895	ENOG4105C3M	thioredoxin reductase
HGD77_03900	ENOG4105CNU	cell division protein FtsK
HGD77_03915	ENOG4107QMS	site-determining protein
HGD77_03930	ENOG4106HNH	Acyl-transferase
HGD77_03935	ENOG4108ZG0	Ompa motb domain protein
HGD77_03940	ENOG4105C4R	Atp-dependent dna helicase
HGD77_03945	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HGD77_03950	ENOG4107QKV	phosphomannomutase
HGD77_03955	ENOG4105CAS	nag kinase
HGD77_03960	ENOG4105E7A	Glutamine amidotransferase
HGD77_03975	ENOG4105VDB	UPF0125 protein
HGD77_03985	ENOG41090R7	Ferric uptake
HGD77_03990	ENOG4105CZX	twitching motility protein
HGD77_03995	ENOG4105CZX	twitching motility protein
HGD77_04000	ENOG4105DFA	alanine racemase domain protein
HGD77_04010	ENOG4105EYH	Exonuclease
HGD77_04015	ENOG4107RH8	nuclease SbcCD subunit D
HGD77_04025	ENOG4105CGD	Nad-dependent epimerase dehydratase
HGD77_04030	ENOG4108DN8	FAD dependent oxidoreductase
HGD77_04035	ENOG4105D52	delta-aminolevulinic acid dehydratase
HGD77_04040	ENOG4108VUY	thioesterase Superfamily protein
HGD77_04045	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HGD77_04055	ENOG4105DFP	Integrase
HGD77_04065	ENOG4105F9F	transposase
HGD77_04075	ENOG4105F9F	transposase
HGD77_04080	ENOG4107QUV	Domain protein
HGD77_04090	ENOG4107R3N	Filamentation induced by cAMP protein fic
HGD77_04095	ENOG4107R3N	Filamentation induced by cAMP protein fic
HGD77_04125	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HGD77_04130	ENOG4105D60	lipoprotein releasing system transmembrane protein
HGD77_04135	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HGD77_04175	ENOG4106UW1	Major Facilitator superfamily
HGD77_04180	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HGD77_04215	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HGD77_04225	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HGD77_04235	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HGD77_04240	ENOG4105VQ7	Rod shape-determining protein MreD
HGD77_04245	ENOG4108Z03	MAF-like protein
HGD77_04250	ENOG4105C03	ribonuclease
HGD77_04270	ENOG4105D8T	Acyltransferase
HGD77_04285	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HGD77_04305	ENOG4105C85	amino acid
HGD77_04310	ENOG4105C7F	AcnD-accessory protein PrpF
HGD77_04315	ENOG4105CTB	Polyprenyl synthetase
HGD77_04320	ENOG4105CK7	Sodium proline symporter
HGD77_04335	ENOG4105D78	K07001 NTE family protein
HGD77_04375	ENOG4107VMU	Membrane
HGD77_04410	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HGD77_04430	ENOG4105CSV	Glutaminase
HGD77_04445	ENOG4105C3R	Methionine synthase
HGD77_04450	ENOG4105CJ3	phosphate transporter
HGD77_04475	ENOG4105D05	Receptor
HGD77_04495	ENOG4108UJV	acyl-CoA thioesterase i
HGD77_04500	ENOG4108I0Y	(ABC) transporter
HGD77_04505	ENOG4105CV6	ABC transporter, permease
HGD77_04510	ENOG4107U91	Rhomboid family
HGD77_04515	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HGD77_04530	ENOG4105C5Q	Transcriptional regulator
HGD77_04535	ENOG4108JNI	Alpha beta hydrolase
HGD77_04540	ENOG4107QZF	nitrite reductase NADPH large subunit
HGD77_04545	ENOG4105VCQ	rubredoxin
HGD77_04550	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HGD77_04570	ENOG4105CKW	Inner membrane protein yedI
HGD77_04575	ENOG4105CGZ	zinc metallopeptidase
HGD77_04590	ENOG4105EEQ	Na H antiporter
HGD77_04600	ENOG4107YZX	Universal stress protein
HGD77_04630	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HGD77_04635	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HGD77_04645	ENOG4105E33	succinate dehydrogenase
HGD77_04650	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HGD77_04655	ENOG4105C7S	Dehydrogenase
HGD77_04660	ENOG4107QN2	dihydrolipoyl dehydrogenase
HGD77_04670	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HGD77_04675	ENOG4105VNT	transposase (IS4 family) protein
HGD77_04680	ENOG4107S78	Band 7 protein
HGD77_04700	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HGD77_04740	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HGD77_04795	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HGD77_04820	ENOG4106H78	methyltransferase
HGD77_04825	ENOG4105CJN	penicillin-binding protein
HGD77_04850	ENOG4105CSM	endonuclease III
HGD77_04855	ENOG4108R3D	Electron transport complex
HGD77_04860	ENOG4105D82	Glutamate dehydrogenase
HGD77_04870	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HGD77_04880	ENOG4107VAM	peptidase, m28
HGD77_04890	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HGD77_04915	ENOG4105DRR	Transcriptional regulator, GntR family
HGD77_04950	ENOG4107RAQ	aminopeptidase
HGD77_04955	ENOG4105WG9	Conserved Protein
HGD77_04965	ENOG4105D0A	hydroxylase
HGD77_04970	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HGD77_04980	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HGD77_04985	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HGD77_04995	ENOG4105W4M	Transport-associated protein
HGD77_05010	ENOG4105E09	nadh pyrophosphatase
HGD77_05020	ENOG4107RZZ	dna polymerase iii epsilon subunit
HGD77_05025	ENOG4105E9H	Lytic Murein transglycosylase
HGD77_05025	ENOG4105E9H	Lytic Murein transglycosylase
HGD77_05035	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HGD77_05040	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HGD77_05080	ENOG4108IQI	permease
HGD77_05100	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HGD77_05105	ENOG4105EKE	dihydroorotase
HGD77_05130	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HGD77_05150	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HGD77_05170	ENOG4105DFP	Integrase
HGD77_05180	ENOG4105C2I	pirin domain protein
HGD77_05195	ENOG4105NX3	Membrane
HGD77_05210	ENOG4105BZU	Histidine kinase
HGD77_05225	ENOG4105EUJ	GTP cyclohydrolase i
HGD77_05240	ENOG4107QYG	anthranilate phosphoribosyltransferase
HGD77_05245	ENOG4105DDQ	anthranilate synthase
HGD77_05445	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HGD77_05485	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HGD77_05490	ENOG4107QNR	UPF0135 protein
HGD77_05495	ENOG4105C0H	protease
HGD77_05505	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HGD77_05510	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
HGD77_05515	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HGD77_05520	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
HGD77_05525	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HGD77_05530	ENOG4105C2W	permease
HGD77_05535	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HGD77_05545	ENOG4107QPN	acyl-Coa dehydrogenase
HGD77_05550	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HGD77_05555	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HGD77_05590	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HGD77_05600	ENOG4105DTR	rard protein
HGD77_05615	ENOG4105KVH	Transcriptional regulator
HGD77_05625	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HGD77_05645	ENOG4108JPW	Aminotransferase
HGD77_05650	ENOG4105DY8	decarboxylase
HGD77_05655	ENOG4105CVA	phosphate
HGD77_05660	ENOG4105C8U	phosphate abc transporter
HGD77_05670	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HGD77_05675	ENOG4105ERU	peptidase
HGD77_05695	ENOG4107QTF	adenylosuccinate lyase
HGD77_05705	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HGD77_05730	ENOG4108Z0R	Transferase
HGD77_05735	ENOG4105DZ1	carboxypeptidase
HGD77_05750	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HGD77_05755	ENOG4108K5P	(LipO)protein
HGD77_05760	ENOG4105CR8	Transcriptional regulator
HGD77_05765	ENOG4105C8Y	Acetylornithine aminotransferase
HGD77_05770	ENOG4105M2J	Glutaredoxin
HGD77_05790	ENOG4105DHU	Bile acid
HGD77_05795	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HGD77_05810	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HGD77_05815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HGD77_05820	ENOG4105D22	carbon starvation protein
HGD77_05825	ENOG4105VCD	cytoplasmic protein
HGD77_05835	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HGD77_05880	ENOG410620I	Diguanylate cyclase
HGD77_05900	ENOG4105KBH	arsR family transcriptional regulator
HGD77_05910	ENOG4105D6J	arsenicaL-resistance protein
HGD77_05915	ENOG4105CAU	Arsenical resistance protein, ArsH
HGD77_05920	ENOG4105H3G	oxidoreductase
HGD77_05925	ENOG4105EYW	Ion transport protein
HGD77_05935	ENOG4105DHQ	Histidine kinase
HGD77_05950	ENOG4107QX9	Thiol disulfide interChange protein
HGD77_05955	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HGD77_05965	ENOG41080HT	Transcriptional regulator, arsr family
HGD77_06000	ENOG4107S1Q	Phosphatase
HGD77_06005	ENOG4108UKZ	OsmC family
HGD77_06010	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HGD77_06015	ENOG4105CPC	Aldo Keto reductase
HGD77_06025	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HGD77_06040	ENOG4105CXT	aspartate transcarbamylase
HGD77_06045	ENOG4105CD3	dihydroorotase
HGD77_06055	ENOG4105CRW	Short chain fatty acid transporter
HGD77_06060	ENOG4107QNJ	CoA-transferase subunit B
HGD77_06070	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HGD77_06080	ENOG4105E39	Enoyl-CoA hydratase
HGD77_06085	ENOG4107QX3	carboxylase
HGD77_06090	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_06095	ENOG4108SGK	Tetr family transcriptional regulator
HGD77_06100	ENOG4105CEY	Amp-dependent synthetase and ligase
HGD77_06120	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HGD77_06125	ENOG4105CHH	sulfate transporter
HGD77_06130	ENOG4108K3A	Glutathione S-transferase
HGD77_06145	ENOG4105M08	Membrane
HGD77_06150	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HGD77_06165	ENOG4105C1J	atp-dependent rna helicase
HGD77_06175	ENOG41069NU	Nitroreductase
HGD77_06200	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HGD77_06210	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HGD77_06215	ENOG4105D0M	Protease HtpX homolog
HGD77_06230	ENOG4105ERG	peptidase m48, ste24p
HGD77_06240	ENOG4105KTH	gatB Yqey
HGD77_06255	ENOG410620I	Diguanylate cyclase
HGD77_06270	ENOG4105E5H	Transposase
HGD77_06295	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
HGD77_06350	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HGD77_06360	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HGD77_06385	ENOG4105I7R	Adenylate cyclase
HGD77_06400	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HGD77_06425	ENOG4105D3G	Pseudouridine synthase
HGD77_06430	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HGD77_06445	ENOG4105EJ2	Transcriptional regulator
HGD77_06465	ENOG4107QS8	(LipO)protein
HGD77_06470	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HGD77_06480	ENOG4105EA8	2-Nitropropane dioxygenase
HGD77_06500	ENOG41066VF	YeeE YedE family protein
HGD77_06510	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HGD77_06520	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HGD77_06545	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HGD77_06550	ENOG4108SHQ	Glutathione S-transferase
HGD77_06580	ENOG4105C2X	Arabinose 5-phosphate isomerase
HGD77_06595	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HGD77_06600	ENOG4108IUZ	ABC transporter
HGD77_06615	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HGD77_06645	ENOG4108Z4U	Ferredoxin
HGD77_06680	ENOG4105C0B	DNA polymerase III (alpha subunit)
HGD77_06685	ENOG4108UMI	ABC transporter, permease
HGD77_06690	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HGD77_06700	ENOG4108YYQ	gCN5-related N-acetyltransferase
HGD77_06710	ENOG4105C12	Phosphoribosylglycinamide synthetase
HGD77_06715	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HGD77_06720	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HGD77_06755	ENOG4108SC4	)-transporter
HGD77_06765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HGD77_06770	ENOG4105CUX	Signal transduction histidine kinase
HGD77_06790	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HGD77_06795	ENOG4105KNE	Phosphatidate cytidylyltransferase
HGD77_06805	ENOG4105DZP	Membrane-associated zinc metalloprotease
HGD77_06810	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGD77_06825	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HGD77_06830	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HGD77_06845	ENOG4105Y3E	Modulates RecA activity (By similarity)
HGD77_06850	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HGD77_06855	ENOG4105VEJ	Heat shock protein
HGD77_06860	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HGD77_06865	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HGD77_06875	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HGD77_06880	ENOG4105K4T	epimerase
HGD77_06885	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HGD77_06895	ENOG4105WH1	Two component transcriptional regulator luxr family
HGD77_06900	ENOG4105BZU	Histidine kinase
HGD77_06905	ENOG4105EZE	Cupin 4 family protein
HGD77_06910	ENOG4108UHJ	MAF-like protein
HGD77_06930	ENOG4105D2N	Aldolase
HGD77_06935	ENOG4108TZV	Membrane
HGD77_06945	ENOG4108RCM	Nitroreductase
HGD77_06985	ENOG4105CX6	glutaminyL-tRNA synthetase
HGD77_06990	ENOG4105FFC	UPF0187 protein
HGD77_07015	ENOG4105EW9	transcriptional regulator AsnC family
HGD77_07020	ENOG4105CK7	Sodium proline symporter
HGD77_07025	ENOG4108IJ0	Aspartate ammonia-lyase
HGD77_07035	ENOG4108JA2	transcriptioN-repair coupling factor
HGD77_07045	ENOG4105F8J	Adenylate Guanylate cyclase
HGD77_07050	ENOG4108ZIT	Ferredoxin, 2FE-2S
HGD77_07065	ENOG4108Z4V	iron-sulfur cluster assembly
HGD77_07070	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HGD77_07080	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HGD77_07095	ENOG4105K70	DNA-binding protein
HGD77_07100	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HGD77_07120	ENOG4105PV3	Inner membrane protein yqiJ
HGD77_07145	ENOG4105HDD	phospholipase
HGD77_07150	ENOG4105CZN	Potassium uptake protein
HGD77_07160	ENOG4105C7B	Threonine dehydratase
HGD77_07165	ENOG4105E66	phosphoriboisomerase A
HGD77_07185	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HGD77_07190	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HGD77_07215	ENOG4105CR4	methylisocitrate lyase
HGD77_07220	ENOG4105BZN	citrate synthase
HGD77_07280	ENOG4105D8G	Major Facilitator superfamily
HGD77_07290	ENOG4105BZU	Histidine kinase
HGD77_07300	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HGD77_07305	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HGD77_07310	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HGD77_07315	ENOG4108Z66	YbaK ebsC protein
HGD77_07345	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HGD77_07350	ENOG4105CMR	udp-glucose 4-epimerase
HGD77_07380	ENOG4105EV9	Alpha Beta Hydrolase
HGD77_07390	ENOG4105CDV	Ompa motb domain protein
HGD77_07415	ENOG41080IJ	Diacylglycerol kinase
HGD77_07425	ENOG4105DHQ	Histidine kinase
HGD77_07430	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HGD77_07435	ENOG4105DIJ	Phosphoethanolamine transferase
HGD77_07450	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HGD77_07455	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HGD77_07480	ENOG4108JQ9	ABC transporter
HGD77_07505	ENOG4105SKE	transcriptional Regulator LysR family
HGD77_07510	ENOG41061H0	Monooxygenase
HGD77_07530	ENOG4105C2W	permease
HGD77_07535	ENOG4105VT2	5-hydroxyisourate hydrolase
HGD77_07565	ENOG4105C26	Dehydrogenase
HGD77_07570	ENOG4108JPW	Aminotransferase
HGD77_07595	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HGD77_07610	ENOG4105E39	Enoyl-CoA hydratase
HGD77_07615	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_07625	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HGD77_07630	ENOG4105C26	Dehydrogenase
HGD77_07635	ENOG4107YNJ	LysR family Transcriptional regulator
HGD77_07670	ENOG4105CEY	Amp-dependent synthetase and ligase
HGD77_07675	ENOG4107RN6	Monooxygenase
HGD77_07685	ENOG4105CSU	acyl-Coa dehydrogenase
HGD77_07690	ENOG4105EA8	2-Nitropropane dioxygenase
HGD77_07695	ENOG4108UKI	Enoyl-CoA hydratase
HGD77_07700	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HGD77_07705	ENOG4105MP9	class II Aldolase
HGD77_07715	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_07725	ENOG4105E39	Enoyl-CoA hydratase
HGD77_07730	ENOG4107RGD	Major Facilitator superfamily
HGD77_07750	ENOG4107QNJ	CoA-transferase subunit B
HGD77_07755	ENOG4107QP7	CoA-transferase subunit A
HGD77_07760	ENOG4107RGD	Major Facilitator superfamily
HGD77_07765	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_07770	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_07780	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HGD77_07785	ENOG4105DDY	UPF0142 protein ycaO
HGD77_07800	ENOG4105C26	Dehydrogenase
HGD77_07805	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HGD77_07820	ENOG4105D05	Receptor
HGD77_07825	ENOG4105DZ2	Transcriptional regulator
HGD77_07845	ENOG4105TMB	Formate nitrite transporter
HGD77_07850	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HGD77_07855	ENOG4107RNU	major facilitator superfamily MFS_1
HGD77_07860	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HGD77_07865	ENOG4105E0C	molybdate abc transporter
HGD77_07870	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HGD77_07875	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HGD77_07880	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HGD77_07885	ENOG4108ZAF	Molybdopterin
HGD77_07895	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HGD77_07910	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HGD77_07915	ENOG4107QZF	nitrite reductase NADPH large subunit
HGD77_07930	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HGD77_07950	ENOG4105DQ4	alcohol dehydrogenase
HGD77_07975	ENOG4105MRR	Transcriptional regulator (By similarity)
HGD77_07980	ENOG4105ESI	atpase involved in dna repair
HGD77_07985	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HGD77_08005	ENOG4107YBY	Hydrolase
HGD77_08020	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HGD77_08025	ENOG4105CEY	Amp-dependent synthetase and ligase
HGD77_08030	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HGD77_08040	ENOG4105D2S	major facilitator superfamily
HGD77_08045	ENOG4108KB2	LysR family Transcriptional regulator
HGD77_08050	ENOG4105DTQ	mandelate racemase muconate lactonizing
HGD77_08055	ENOG4105NN7	muconolactone delta-isomerase
HGD77_08075	ENOG4105FUY	alpha subunit
HGD77_08080	ENOG4108UKV	benzoate 1,2-dioxygenase
HGD77_08085	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HGD77_08090	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
HGD77_08095	ENOG4105DKK	Benzoate
HGD77_08100	ENOG4107QP7	CoA-transferase subunit A
HGD77_08105	ENOG4107QNJ	CoA-transferase subunit B
HGD77_08110	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_08115	ENOG4105F2Z	3-oxoadipate enol-lactonase
HGD77_08140	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_08145	ENOG4105CSU	acyl-Coa dehydrogenase
HGD77_08150	ENOG41062JF	Transcriptional regulator
HGD77_08170	ENOG4105C6T	cysteine synthase
HGD77_08185	ENOG41080HT	Transcriptional regulator, arsr family
HGD77_08205	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HGD77_08210	ENOG4105CUY	Mechanosensitive ion channel
HGD77_08215	ENOG4105BZ1	(ABC) transporter
HGD77_08220	ENOG4108ZX5	transcriptional regulator
HGD77_08225	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HGD77_08230	ENOG4105CZM	Major Facilitator
HGD77_08235	ENOG4105CZX	twitching motility protein
HGD77_08250	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HGD77_08265	ENOG4107RZC	phospholipase d
HGD77_08320	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_08330	ENOG4105KK6	nuclease
HGD77_08340	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HGD77_08345	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HGD77_08365	ENOG4105CSU	acyl-Coa dehydrogenase
HGD77_08370	ENOG4105EEF	Alkane 1-monooxygenase
HGD77_08375	ENOG4105E7U	AraC family transcriptional regulator
HGD77_08380	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HGD77_08385	ENOG4107TSN	permease
HGD77_08390	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HGD77_08430	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HGD77_08455	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_08460	ENOG4108MJ3	acetyltransferase
HGD77_08495	ENOG4108Q67	UPF0319 protein
HGD77_08510	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGD77_08545	ENOG4105W87	Cbs domain
HGD77_08550	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HGD77_08580	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HGD77_08590	ENOG4105C28	cystathionine
HGD77_08610	ENOG4105K59	histidine triad (HIT) protein
HGD77_08630	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HGD77_08635	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HGD77_08650	ENOG4105VNT	transposase (IS4 family) protein
HGD77_08655	ENOG4105CNI	cell division protein FtsW
HGD77_08665	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HGD77_08670	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HGD77_08715	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HGD77_08730	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HGD77_08735	ENOG4105CC0	LysR family Transcriptional regulator
HGD77_08740	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HGD77_08745	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HGD77_08785	ENOG4107QIJ	Aconitate hydratase 2
HGD77_08815	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HGD77_08825	ENOG4105VNT	transposase (IS4 family) protein
HGD77_08870	ENOG4105CFU	surface antigen
HGD77_08875	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HGD77_08925	ENOG4105D06	uba thif-type nad fad binding protein
HGD77_08940	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_08960	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HGD77_08965	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HGD77_08980	ENOG4105DEN	Luciferase family
HGD77_09005	ENOG4105E2S	oxidase) subunit II
HGD77_09010	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HGD77_09015	ENOG4105CCU	oxidase (Subunit III)
HGD77_09020	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HGD77_09045	ENOG4105CDU	Replicative dna helicase
HGD77_09050	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HGD77_09085	ENOG4105CBC	glutamate synthase
HGD77_09105	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
HGD77_09110	ENOG4105C0A	alcohol dehydrogenase
HGD77_09120	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HGD77_09140	ENOG4105CHR	reductase
HGD77_09145	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_09160	ENOG4105F52	Transcriptional regulator
HGD77_09165	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HGD77_09170	ENOG4108NIW	Leucine export protein LeuE
HGD77_09175	ENOG4105DKK	Benzoate
HGD77_09190	ENOG41081QV	Universal stress protein
HGD77_09195	ENOG41081QV	Universal stress protein
HGD77_09205	ENOG4105CD8	aminopeptidase N
HGD77_09230	ENOG4105EE5	Membrane protein terC
HGD77_09250	ENOG4107QP3	malate synthase g
HGD77_09255	ENOG4105D6Z	AFG1 family ATPase
HGD77_09270	ENOG4105DWU	Membrane
HGD77_09285	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HGD77_09290	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HGD77_09305	ENOG4108Z6B	deaminase
HGD77_09325	ENOG4108RTD	type II secretion system protein K
HGD77_09345	ENOG4105R8C	Transcriptional regulator
HGD77_09350	ENOG4105F8V	Hydrolase, tatD family
HGD77_09360	ENOG4107QRG	dna polymerase iii
HGD77_09370	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HGD77_09390	ENOG4105FA0	parb-like partition protein
HGD77_09405	ENOG4108S0S	Nucleotidyl transferase
HGD77_09410	ENOG4105EHM	Aminoglycoside phosphotransferase
HGD77_09415	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HGD77_09420	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HGD77_09425	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HGD77_09435	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HGD77_09440	ENOG4105K8N	protein family UPF0079, ATPase
HGD77_09460	ENOG4105I08	Pseudouridine synthase
HGD77_09475	ENOG4107QUV	Domain protein
HGD77_09495	ENOG4105CQ7	ATP-dependent helicase
HGD77_09500	ENOG4105D3R	alkyl hydroperoxide reductase
HGD77_09520	ENOG4108JU3	Alkyl hydroperoxide reductase
HGD77_09535	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HGD77_09550	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
HGD77_09560	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HGD77_09580	ENOG41067CV	Integrase
HGD77_09635	ENOG4105DZR	Type I site-specific deoxyribonuclease
HGD77_09660	ENOG4105CVR	type I restriction-modification system
HGD77_09675	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
HGD77_09680	ENOG4108IY8	ABC, transporter
HGD77_09685	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HGD77_09690	ENOG4105E89	ABC transporter
HGD77_09740	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HGD77_09780	ENOG4105C3G	gtp-binding protein
HGD77_09795	ENOG4108UMN	azlc family
HGD77_09800	ENOG4105ZED	uncharacterized protein ygaH
HGD77_09815	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HGD77_09820	ENOG4105CHM	Aminotransferase
HGD77_09825	ENOG4108V06	Glutathione peroxidase
HGD77_09830	ENOG4105E0X	reductase
HGD77_09835	ENOG4105CHM	Aminotransferase
HGD77_09855	ENOG4108R99	pseudouridine synthase
HGD77_09860	ENOG4105VT2	5-hydroxyisourate hydrolase
HGD77_09880	ENOG4105DZ1	carboxypeptidase
HGD77_09890	ENOG4105CEP	NADH dehydrogenase
HGD77_09895	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HGD77_09910	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HGD77_09920	ENOG4105EW9	transcriptional regulator AsnC family
HGD77_09925	ENOG4108UMN	azlc family
HGD77_09940	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HGD77_09945	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HGD77_09950	ENOG4105CFH	Aspartokinase
HGD77_09960	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HGD77_09980	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HGD77_09985	ENOG4105C7N	Xanthine uracil vitamin C permease
HGD77_10010	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HGD77_10015	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HGD77_10020	ENOG4105CQC	Prephenate dehydratase
HGD77_10025	ENOG4107R7Y	intracellular protease Pfpi family
HGD77_10035	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_10040	ENOG4105CK2	sodium dicarboxylate symporter
HGD77_10050	ENOG4105VUT	cytoplasmic protein
HGD77_10055	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HGD77_10060	ENOG4105BZ4	penicillin-binding protein
HGD77_10070	ENOG4105M6F	mutator MutT protein
HGD77_10080	ENOG4105DHQ	Histidine kinase
HGD77_10085	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HGD77_10095	ENOG4107QHF	type ii secretion system protein e
HGD77_10105	ENOG4108R96	Methyltransferase, YaeB family
HGD77_10110	ENOG4105DP0	ferredoxin-NADP reductase
HGD77_10130	ENOG4108Z6Z	Transcriptional regulator
HGD77_10135	ENOG4105CFP	Peptidase U32
HGD77_10140	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HGD77_10145	ENOG4108JU3	Alkyl hydroperoxide reductase
HGD77_10165	ENOG4105NXH	GreA GreB family elongation factor
HGD77_10220	ENOG4105BZU	Histidine kinase
HGD77_10230	ENOG4105DA5	(ABC) transporter
HGD77_10235	ENOG4105E3A	(ABC) transporter
HGD77_10250	ENOG4105CVE	Lytic murein transglycosylase
HGD77_10275	ENOG4105CE9	30S ribosomal protein S2
HGD77_10280	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HGD77_10290	ENOG4107QI1	Mate efflux family protein
HGD77_10310	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HGD77_10315	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HGD77_10320	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HGD77_10330	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HGD77_10335	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HGD77_10345	ENOG4105C3F	Signal peptidase i
HGD77_10360	ENOG4105C0H	protease
HGD77_10365	ENOG4108IYU	L-aspartate oxidase
HGD77_10450	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HGD77_10495	ENOG4105HHA	aminodeoxychorismate lyase
HGD77_10505	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HGD77_10510	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HGD77_10520	ENOG4108I5D	sulfate abc transporter
HGD77_10525	ENOG4105ECW	sulfate abc transporter
HGD77_10530	ENOG4108IJ6	ABC transporter
HGD77_10535	ENOG4107R11	Transcriptional regulator
HGD77_10555	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HGD77_10560	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HGD77_10570	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGD77_10615	ENOG4108W5M	transcriptional regulator
HGD77_10630	ENOG4108ETH	Formylglycinamide ribotide synthetase
HGD77_10650	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HGD77_10665	ENOG4105CH2	amidohydrolase
HGD77_10670	ENOG4107YD3	Thioesterase
HGD77_10675	ENOG4105E02	MotA TolQ exbB proton channel
HGD77_10680	ENOG4105M8F	Biopolymer transport protein exbD tolR
HGD77_10690	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HGD77_10695	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HGD77_10740	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HGD77_10745	ENOG4105C02	permease
HGD77_10750	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HGD77_10755	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HGD77_10760	ENOG4108MUZ	hydrolase
HGD77_10780	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HGD77_10800	ENOG4108UPT	UPF0178 protein
HGD77_10820	ENOG4107KET	secretion protein, HlyD family
HGD77_10840	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HGD77_10850	ENOG4105C10	Electron transfer flavoprotein
HGD77_10855	ENOG4105BZJ	Electron transfer flavoprotein
HGD77_10860	ENOG4105N14	lysine exporter protein LysE YggA
HGD77_10865	ENOG4108YXU	transcriptional regulator AsnC family
HGD77_10875	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HGD77_10890	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HGD77_10900	ENOG4105C85	amino acid
HGD77_10905	ENOG4105BZG	amino acid carrier protein
HGD77_10915	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HGD77_10950	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HGD77_10955	ENOG4105SYT	Methylenetetrahydrofolate reductase
HGD77_10960	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HGD77_10980	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HGD77_11000	ENOG4108RRZ	Transcription elongation factor GreB
HGD77_11015	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HGD77_11020	ENOG4105E4C	Lytic transglycosylase catalytic
HGD77_11025	ENOG4105D0M	Protease HtpX homolog
HGD77_11035	ENOG4105CJW	magnesium transporter
HGD77_11040	ENOG4105BZS	acriflavin resistance protein
HGD77_11045	ENOG4105BZS	acriflavin resistance protein
HGD77_11050	ENOG4107RET	Isocitrate lyase
HGD77_11060	ENOG4105C37	(CBS) domain
HGD77_11100	ENOG4105EEI	dihydropteroate synthase
HGD77_11110	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HGD77_11120	ENOG4105HBR	Rna-binding protein
HGD77_11140	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HGD77_11145	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HGD77_11155	ENOG4108Q5F	Tetr family transcriptional regulator
HGD77_11160	ENOG4108UQ8	endoribonuclease L-psp
HGD77_11185	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HGD77_11205	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HGD77_11210	ENOG4105C34	Pseudouridine synthase
HGD77_11215	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGD77_11220	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HGD77_11225	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HGD77_11235	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HGD77_11265	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HGD77_11270	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HGD77_11295	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HGD77_11320	ENOG4107T5V	SNARE associated Golgi
HGD77_11340	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HGD77_11365	ENOG4105CUB	amino acid
HGD77_11375	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HGD77_11380	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HGD77_11385	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HGD77_11395	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HGD77_11405	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HGD77_11420	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HGD77_11425	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HGD77_11430	ENOG4105BZS	acriflavin resistance protein
HGD77_11435	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HGD77_11440	ENOG4105K8R	UPF0145 protein
HGD77_11445	ENOG4105K8R	UPF0145 protein
HGD77_11490	ENOG4108VWS	Yaeq family
HGD77_11495	ENOG4105CKI	cobalamin synthesis protein
HGD77_11515	ENOG4108W5M	transcriptional regulator
HGD77_11530	ENOG4108S4H	thioesterase Superfamily protein
HGD77_11540	ENOG4105D78	K07001 NTE family protein
HGD77_11545	ENOG4105FGV	Chromate
HGD77_11550	ENOG4105BZG	amino acid carrier protein
HGD77_11555	ENOG4105D6U	Sodium Glutamate Symporter
HGD77_11640	ENOG4105WD1	Membrane
HGD77_11665	ENOG4105CBS	Chea signal transduction histidine kinase
HGD77_11670	ENOG4105C8Q	Methyl-accepting chemotaxis
HGD77_11680	ENOG4108ZGA	chew protein
HGD77_11685	ENOG4105M3Z	response regulator
HGD77_11690	ENOG4108UNF	response regulator
HGD77_11700	ENOG4105D0S	secretion protein (HlyD
HGD77_11745	ENOG4105D1F	ATP-binding protein
HGD77_11765	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HGD77_11780	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HGD77_11805	ENOG4105K6H	D-cysteine desulfhydrase
HGD77_11815	ENOG4105CBX	hi0933 family
HGD77_11840	ENOG4107FQ9	ethanolamine ammonia-lyase
HGD77_11845	ENOG4105CPD	ethanolamine ammonia-lyase
HGD77_11865	ENOG4105DP0	ferredoxin-NADP reductase
HGD77_11870	ENOG4105DUM	transcriptional regulator, lysR family
HGD77_11900	ENOG4105C8S	subunit m
HGD77_11905	ENOG4105D65	subunit l
HGD77_11910	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HGD77_11915	ENOG4107UFS	subunit j
HGD77_11920	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HGD77_11930	ENOG4108IEH	NADH dehydrogenase subunit g
HGD77_11935	ENOG4107QIZ	NADH dehydrogenase
HGD77_11940	ENOG4105GKE	subunit e
HGD77_11955	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HGD77_11965	ENOG4105JJR	Histidine kinase
HGD77_11970	ENOG4107EXC	regulatoR
HGD77_11975	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HGD77_11985	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HGD77_12020	ENOG4105E5H	Transposase
HGD77_12140	ENOG4107XGZ	Hydrolase
HGD77_12145	ENOG4105DWF	phosphomethylpyrimidine kinase
HGD77_12170	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HGD77_12190	ENOG4105D3G	Pseudouridine synthase
HGD77_12230	ENOG4108I0Z	Aconitate hydratase
HGD77_12235	ENOG4105E3B	Multicopper oxidase
HGD77_12240	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HGD77_12260	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HGD77_12265	ENOG4105TW1	Carbohydrate-selective porin OprB
HGD77_12290	ENOG4105CI3	gtp-binding protein typa
HGD77_12295	ENOG4105C2W	permease
HGD77_12305	ENOG4108IQI	permease
HGD77_12320	ENOG4106855	Competence protein
HGD77_12325	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_12345	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HGD77_12350	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HGD77_12355	ENOG4108R6W	Transcriptional regulator, ARAC family
HGD77_12360	ENOG4105CHU	acetyl-coa acetyltransferase
HGD77_12365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HGD77_12385	ENOG4108UT2	hemolysin iii
HGD77_12390	ENOG4105CSH	Transporter
HGD77_12405	ENOG4107RZC	phospholipase d
HGD77_12415	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HGD77_12460	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HGD77_12465	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HGD77_12470	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HGD77_12475	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HGD77_12480	ENOG4108UJD	30S ribosomal protein S9
HGD77_12485	ENOG4107MKT	Stringent starvation protein a
HGD77_12490	ENOG4105KB2	stringent starvation protein b
HGD77_12560	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HGD77_12565	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HGD77_12575	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HGD77_12580	ENOG4105D3R	alkyl hydroperoxide reductase
HGD77_12595	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HGD77_12615	ENOG4108ZX5	transcriptional regulator
HGD77_12635	ENOG4105E9K	Isocitrate dehydrogenase
HGD77_12645	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HGD77_12655	ENOG4108V0P	LemA family
HGD77_12670	ENOG4105VIE	preprotein translocase, subunit YajC
HGD77_12675	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HGD77_12680	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HGD77_12690	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HGD77_12705	ENOG4105C6T	cysteine synthase
HGD77_12710	ENOG4105BZU	Histidine kinase
HGD77_12720	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HGD77_12725	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HGD77_12735	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HGD77_12740	ENOG4105W8H	transhydrogenase (subunit alpha
HGD77_12745	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HGD77_12775	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HGD77_12785	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HGD77_12790	ENOG4105W5Q	DNA repair protein (RadC
HGD77_12795	ENOG4105FFC	UPF0187 protein
HGD77_12800	ENOG4105DB7	PHP domain protein
HGD77_12810	ENOG4105K9H	YciI-like protein
HGD77_12845	ENOG4105NAU	thioesterase Superfamily protein
HGD77_12905	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HGD77_12910	ENOG4105D6S	protein involved in catabolism of external DNA
HGD77_12950	ENOG4105E4C	Lytic transglycosylase catalytic
HGD77_12955	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HGD77_12960	ENOG4105C9A	Phoh family
HGD77_13010	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HGD77_13015	ENOG4107S2Z	UPF0761 membrane protein
HGD77_13035	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HGD77_13075	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HGD77_13085	ENOG4105DGW	oligopeptidase A
HGD77_13090	ENOG4105VKU	nucleicacid-binding protein
HGD77_13100	ENOG4105EMK	carboxylate amino acid amine transporter
HGD77_13130	ENOG4105C1G	acyl-Coa dehydrogenase
HGD77_13135	ENOG4105CT3	Monooxygenase
HGD77_13140	ENOG4108ZT0	50S ribosomal protein l17
HGD77_13145	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HGD77_13150	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HGD77_13160	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGD77_13170	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HGD77_13185	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HGD77_13195	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HGD77_13200	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HGD77_13250	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HGD77_13260	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HGD77_13265	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HGD77_13285	ENOG4105C28	cystathionine
HGD77_13305	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HGD77_13325	ENOG4105C29	acyl-CoA thioesterase
HGD77_13330	ENOG4105E55	glycerol-3-phosphate acyltransferase
HGD77_13350	ENOG4105CB5	ATP-dependent DNA helicase recG
HGD77_13355	ENOG4105MJ2	Competence protein
HGD77_13365	ENOG4108URH	decarboxylase
HGD77_13370	ENOG4107QUT	magnesium and cobalt transport protein CorA
HGD77_13390	ENOG4107PE3	Mammalian cell entry related domain protein
HGD77_13395	ENOG4105CY3	ABC transporter, permease
HGD77_13400	ENOG4105DHJ	ABC, transporter
HGD77_13405	ENOG4105C1J	atp-dependent rna helicase
HGD77_13410	ENOG4105ECY	inositol monophosphatase
HGD77_13425	ENOG4105D4P	Coproporphyrinogen iii oxidase
HGD77_13430	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HGD77_13445	ENOG4105CSU	acyl-Coa dehydrogenase
HGD77_13450	ENOG4105VEQ	Cold shock protein
HGD77_13470	ENOG4105CSA	Coproporphyrinogen iii oxidase
HGD77_13480	ENOG4107QI1	Mate efflux family protein
HGD77_13495	ENOG4105NRA	50s ribosomal protein l31 type b
HGD77_13500	ENOG4105WMR	Protein CrcB homolog
HGD77_13535	ENOG4105IPI	Membrane
HGD77_13540	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HGD77_13545	ENOG4105EM2	membrane
HGD77_13550	ENOG4105VCH	membrane
HGD77_13560	ENOG4107QF7	multi-drug
HGD77_13570	ENOG4105CQB	FAD linked oxidase domain protein
HGD77_13575	ENOG4108JQ1	Dehydrogenase
HGD77_13625	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HGD77_13630	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
HGD77_13635	ENOG4107IFA	Lipase (EC 3.1.1.3)
HGD77_13640	ENOG4107IFA	Lipase (EC 3.1.1.3)
HGD77_13645	ENOG4107IFA	Lipase (EC 3.1.1.3)
HGD77_13650	ENOG4107IFA	Lipase (EC 3.1.1.3)
HGD77_13655	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HGD77_13665	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HGD77_13670	ENOG4105K5M	30s ribosomal protein S16
HGD77_13690	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HGD77_13695	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HGD77_13700	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HGD77_13705	ENOG4105KME	endoribonuclease L-psp
HGD77_13710	ENOG4105W53	bacterioferritin-associated ferredoxin
HGD77_13720	ENOG4108UQY	Iron-storage protein
HGD77_13725	ENOG4108YSG	O-Antigen polymerase
HGD77_13755	ENOG4108V0P	LemA family
HGD77_13760	ENOG4105BZ8	glutamate synthase
HGD77_13765	ENOG4105CBC	glutamate synthase
HGD77_13785	ENOG4105E4G	Type IV pilus
HGD77_13810	ENOG4108JQC	penicillin-binding protein 1A
HGD77_13815	ENOG4105DHI	Methyltransferase
HGD77_13820	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HGD77_13825	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HGD77_13830	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HGD77_13850	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HGD77_13855	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HGD77_13865	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HGD77_13885	ENOG4105C5H	ABC transporter
HGD77_13895	ENOG4105PDP	Short chain dehydrogenase
HGD77_13900	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HGD77_13915	ENOG4105D65	subunit l
HGD77_13920	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HGD77_13925	ENOG4107R4Z	monovalent cation h antiporter subunit d
HGD77_13930	ENOG4105SC1	monovalent cation H antiporter subunit E
HGD77_13935	ENOG4105W4C	monovalent cation H antiporter subunit F
HGD77_13940	ENOG4105KJM	monovalent cation h antiporter subunit g
HGD77_13945	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HGD77_13955	ENOG4105CHV	Transcription elongation factor NusA
HGD77_13960	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HGD77_13990	ENOG4107EJC	Preprotein translocase subunit SecG
HGD77_14000	ENOG4107QHF	type ii secretion system protein e
HGD77_14015	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HGD77_14025	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HGD77_14030	ENOG4105NBK	UPF0345 protein
HGD77_14035	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HGD77_14045	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HGD77_14055	ENOG4105BZ1	(ABC) transporter
HGD77_14060	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HGD77_14065	ENOG4105DFG	type I secretion outer membrane protein
HGD77_14080	ENOG41087AY	ADP-Ribose pyrophosphatase
HGD77_14085	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HGD77_14095	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HGD77_14105	ENOG4105CNI	cell division protein FtsW
HGD77_14120	ENOG4105CE1	Ferrous iron transport protein b
HGD77_14130	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HGD77_14135	ENOG4105T95	Thiol disulfide interChange protein
HGD77_14140	ENOG4105D6E	homoserine dehydrogenase
HGD77_14150	ENOG41061WM	D-Alanyl-D-Alanine
HGD77_14165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HGD77_14175	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HGD77_14180	ENOG4108K5H	permease YjgP YjgQ family protein
HGD77_14185	ENOG4108M8S	permease YjgP YjgQ family protein
HGD77_14205	ENOG4105DQR	SNARE associated Golgi
HGD77_14220	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HGD77_14230	ENOG4105BZU	Histidine kinase
HGD77_14245	ENOG4105C0P	Mg chelatase subunit ChlI
HGD77_14255	ENOG4105E5H	Transposase
HGD77_14265	ENOG4105IYK	transposase
HGD77_14320	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HGD77_14385	ENOG4105C0P	Mg chelatase subunit ChlI
HGD77_14405	ENOG4105F0N	pyrophosphate phospho-hydrolase
HGD77_14425	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HGD77_14430	ENOG41079KZ	Major Facilitator Superfamily
HGD77_14435	ENOG4105EN6	Membrane
HGD77_14440	ENOG4105K5B	UPF0225 protein
HGD77_14445	ENOG4105EE5	Membrane protein terC
HGD77_14450	ENOG4108URH	decarboxylase
HGD77_14480	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HGD77_14485	ENOG4105CSH	Transporter
HGD77_14500	ENOG4105CCT	upf0313 protein
HGD77_14505	ENOG4105D94	Major Facilitator Superfamily
HGD77_14555	ENOG4105C79	DNA protecting protein DprA
HGD77_14565	ENOG4105SX7	Transporter
HGD77_14570	ENOG4108V06	Glutathione peroxidase
HGD77_14580	ENOG4105EUB	pirin domain protein
HGD77_14585	ENOG4105C26	Dehydrogenase
HGD77_14605	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HGD77_14655	ENOG4105FDK	ABC transporter
HGD77_14665	ENOG410829K	Lysine exporter protein (Lyse ygga)
HGD77_14670	ENOG4105EZR	dyp-type peroxidase family protein
HGD77_14725	ENOG4107QJQ	Mate efflux family protein
HGD77_14740	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HGD77_14745	ENOG4105BZU	Histidine kinase
HGD77_14765	ENOG4108RXX	maleylacetoacetate isomerase
HGD77_14770	ENOG4105EUB	pirin domain protein
HGD77_14775	ENOG4105BZU	Histidine kinase
HGD77_14780	ENOG4105BZU	Histidine kinase
HGD77_14785	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HGD77_14790	ENOG4105DQR	SNARE associated Golgi
HGD77_14805	ENOG4107QJE	Chromosome Partitioning Protein
HGD77_14815	ENOG4105M85	Bola protein
HGD77_14850	ENOG4105ZTP	Protein of unknown function (DUF1376)
HGD77_14900	ENOG4105C26	Dehydrogenase
HGD77_14905	ENOG4105F4X	arginine
HGD77_14910	ENOG4105C8Y	Acetylornithine aminotransferase
HGD77_14915	ENOG4105D82	Glutamate dehydrogenase
HGD77_14930	ENOG4105F9F	transposase
HGD77_14960	ENOG4105M6F	mutator MutT protein
HGD77_15000	ENOG4105KT5	UmuD protein
HGD77_15005	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HGD77_15050	ENOG4105DGI	Alkaline phosphatase
HGD77_15075	ENOG4108JJA	ABC, transporter
HGD77_15080	ENOG4105DFG	type I secretion outer membrane protein
HGD77_15140	ENOG4107R1I	NAD-dependent malic enzyme
HGD77_15155	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HGD77_15160	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HGD77_15175	ENOG4108ZAI	phosphatidylglycerophosphatase a
HGD77_15185	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HGD77_15230	ENOG4107QKV	phosphomannomutase
HGD77_15235	ENOG4108MRJ	
HGD77_15240	ENOG4105CMR	udp-glucose 4-epimerase
HGD77_15250	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HGD77_15255	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HGD77_15280	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HGD77_15285	ENOG4107STW	synthase
HGD77_15305	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HGD77_15310	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HGD77_15315	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HGD77_15320	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HGD77_15345	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HGD77_15350	ENOG4107WZ3	Transferase
HGD77_15355	ENOG4105D3Q	Sugar transferase
HGD77_15360	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HGD77_15365	ENOG4105CGN	Glycosyl transferase (Group 1
HGD77_15375	ENOG4105CG5	Glycosyl transferase (Group 1
HGD77_15400	ENOG4107QQG	Dehydrogenase
HGD77_15435	ENOG4105E5H	Transposase
HGD77_15495	ENOG4105K78	MarR family Transcriptional regulator
HGD77_15505	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HGD77_15510	ENOG4105NF4	modulator of drug activity
HGD77_15515	ENOG4105HEI	LysR family (Transcriptional regulator
HGD77_15545	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HGD77_15550	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HGD77_15600	ENOG41066UD	Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium
HGD77_15630	ENOG4105E5H	Transposase
HGD77_15655	ENOG4108WUH	Transcriptional regulator, TetR family
HGD77_15665	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HGD77_15690	ENOG4108I6A	alcohol dehydrogenase
HGD77_15705	ENOG4105C4W	S-formylglutathione hydrolase
HGD77_15720	ENOG4108JA1	polyketide synthase
HGD77_15725	ENOG4107QPD	alcohol dehydrogenase
HGD77_15730	ENOG4105EJC	lysr family transcriptional regulator
HGD77_15735	ENOG4105EMU	Dehydrogenase
HGD77_15845	ENOG4108BUD	transposase
HGD77_15855	ENOG4108BUD	transposase
HGD77_15860	ENOG4105CAU	Arsenical resistance protein, ArsH
HGD77_15875	ENOG4105E3B	Multicopper oxidase
HGD77_15890	ENOG4105GR3	Histidine kinase
HGD77_15895	ENOG4107PU6	Membrane
HGD77_15900	ENOG4105C59	p-type ATPase
HGD77_15935	ENOG4105F9F	transposase
HGD77_15995	ENOG4108BUD	transposase
HGD77_16030	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HGD77_16035	ENOG4105K56	Transcriptional regulator
HGD77_16045	ENOG4105CQM	Urea amidohydrolase subunit alpha
HGD77_16055	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HGD77_16060	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HGD77_16075	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HGD77_16110	ENOG4107QJE	Chromosome Partitioning Protein
HGD77_16170	ENOG4105E0K	tonB-dependent siderophore receptor
HGD77_16185	ENOG4107RR1	TRANSCRIPTIONal
HGD77_16190	ENOG4105C0A	alcohol dehydrogenase
HGD77_16215	ENOG4105CNM	Receptor
HGD77_16235	ENOG4107KET	secretion protein, HlyD family
HGD77_16255	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HGD77_16260	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HGD77_16265	ENOG4105C8Y	Acetylornithine aminotransferase
HGD77_16270	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HGD77_16275	ENOG410825B	Type 11 methyltransferase
HGD77_16285	ENOG4105DHQ	Histidine kinase
HGD77_16295	ENOG4105DAA	L-lactate
HGD77_16300	ENOG41073TP	transcriptional regulator
HGD77_16315	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HGD77_16320	ENOG4105DE4	1-phosphofructokinase
HGD77_16335	ENOG4105C0D	helicase
HGD77_16465	ENOG4105K4U	addiction module toxin, RelE StbE family
HGD77_16565	ENOG4107Y80	Major Facilitator superfamily
HGD77_16625	ENOG4105E4C	Lytic transglycosylase catalytic
HGD77_16630	ENOG4105C3F	Signal peptidase i
HGD77_16815	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
HGD77_16840	ENOG4105CHH	sulfate transporter
HGD77_16860	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone