locus-tag	class	description
MP622_00015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MP622_00030	COG0583	DNA-binding transcription factor activity
MP622_00040	COG1113	amino acid transport
MP622_00050	COG0625	glutathione transferase activity
MP622_00070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MP622_00075	COG1522	sequence-specific DNA binding
MP622_00080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MP622_00095	COG0084	hydrolase, TatD family'
MP622_00110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MP622_00125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MP622_00135	COG0641	radical SAM
MP622_00140	COG3119	arylsulfatase activity
MP622_00150	COG2814	Major facilitator Superfamily
MP622_00160	COG0789	Transcriptional regulator
MP622_00165	COG0697	spore germination
MP622_00200	COG0004	ammonium transporteR
MP622_00215	COG3622	Belongs to the hyi family
MP622_00220	COG2084	Dehydrogenase
MP622_00225	COG1024	Enoyl-CoA hydratase
MP622_00230	COG0784	Response regulator, receiver
MP622_00230	COG2205	protein histidine kinase activity
MP622_00230	COG5002	protein histidine kinase activity
MP622_00235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MP622_00250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MP622_00255	COG3956	TIGRFAM MazG family protein
MP622_00260	COG1555	photosystem II stabilization
MP622_00265	COG0617	tRNA 3'-terminal CCA addition
MP622_00270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MP622_00285	COG1660	Displays ATPase and GTPase activities
MP622_00295	COG3028	Belongs to the UPF0307 family
MP622_00300	COG0318	PFAM AMP-dependent synthetase and ligase
MP622_00320	COG0625	glutathione transferase activity
MP622_00335	COG1238	metal cluster binding
MP622_00370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MP622_00375	COG0072	phenylalanine-tRNA ligase activity
MP622_00400	COG0248	Ppx GppA phosphatase
MP622_00410	COG0037	tRNA processing
MP622_00455	COG1764	response to oxidative stress
MP622_00460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MP622_00530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MP622_00540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MP622_00600	COG1214	PFAM Peptidase M22, glycoprotease
MP622_00605	COG1968	undecaprenyl-diphosphatase activity
MP622_00620	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MP622_00630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MP622_00640	COG2132	Multicopper oxidase
MP622_00670	COG0351	phosphomethylpyrimidine kinase
MP622_00670	COG0352	thiamine-phosphate diphosphorylase activity
MP622_00670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MP622_00700	COG0251	oxidation-reduction process
MP622_00705	COG1113	amino acid transport
MP622_00715	COG1981	membrane
MP622_00730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MP622_00740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MP622_00745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MP622_00755	COG0456	acetyltransferase
MP622_00765	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MP622_00770	COG0492	ferredoxin-NADP+ reductase activity
MP622_00775	COG1674	ftsk spoiiie
MP622_00795	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MP622_00800	COG2894	cell division
MP622_00805	COG0850	regulation of cytokinetic process
MP622_00815	COG0204	Acyl-transferase
MP622_00820	COG2885	chlorophyll binding
MP622_00825	COG0210	DNA helicase
MP622_00830	COG0756	dUTP diphosphatase activity
MP622_00835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MP622_00840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MP622_00850	COG0121	glutamine amidotransferase
MP622_00865	COG2914	Belongs to the UPF0125 (RnfH) family
MP622_00870	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MP622_00875	COG0735	belongs to the Fur family
MP622_00885	COG0420	3'-5' exonuclease activity
MP622_00900	COG1090	epimerase
MP622_00915	COG2050	protein possibly involved in aromatic compounds catabolism
MP622_00925	COG2814	Major facilitator Superfamily
MP622_00930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MP622_00940	COG0582	viral genome integration into host DNA
MP622_01050	COG4264	IucA IucC family
MP622_01060	COG2814	Major facilitator Superfamily
MP622_01070	COG4264	IucA IucC family
MP622_01115	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MP622_01125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MP622_01130	COG0642	Histidine kinase
MP622_01160	COG3046	protein related to deoxyribodipyrimidine photolyase
MP622_01175	COG0583	DNA-binding transcription factor activity
MP622_01210	COG1414	Transcriptional regulator
MP622_01215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MP622_01230	COG2814	Major facilitator Superfamily
MP622_01235	COG2030	dehydratase
MP622_01235	COG1012	belongs to the aldehyde dehydrogenase family
MP622_01240	COG3396	Phenylacetate-CoA oxygenase
MP622_01245	COG3460	Phenylacetate-CoA oxygenase
MP622_01250	COG3396	Phenylacetate-CoA oxygenase
MP622_01255	COG2151	metal-sulfur cluster biosynthetic enzyme
MP622_01260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MP622_01265	COG1024	Enoyl-CoA hydratase
MP622_01270	COG1024	Enoyl-CoA hydratase
MP622_01275	COG1250	3-hydroxyacyl-CoA dehydrogenase
MP622_01280	COG0183	Belongs to the thiolase family
MP622_01285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MP622_01290	COG3327	negative regulation of DNA-templated transcription, initiation
MP622_01305	COG3152	Membrane
MP622_01315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MP622_01315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MP622_01325	COG0489	protein tyrosine kinase activity
MP622_01365	COG0442	prolyl-tRNA aminoacylation
MP622_01375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP622_01400	COG0840	transmembrane signaling receptor activity
MP622_01415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MP622_01430	COG2832	Protein of unknown function (DUF454)
MP622_01490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MP622_01500	COG1289	transmembrane transporter activity
MP622_01505	COG2814	Major facilitator Superfamily
MP622_01545	COG0659	secondary active sulfate transmembrane transporter activity
MP622_01555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MP622_01585	COG0640	Transcriptional regulator
MP622_01595	COG0798	PFAM Bile acid sodium symporter
MP622_01600	COG0431	NADPH-dependent FMN reductase
MP622_01605	COG0492	ferredoxin-NADP+ reductase activity
MP622_01620	COG2072	flavoprotein involved in K transport
MP622_01670	COG0110	maltose O-acetyltransferase activity
MP622_01675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MP622_01690	COG0505	Belongs to the CarA family
MP622_01715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MP622_01720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MP622_01725	COG2304	oxidoreductase activity
MP622_01775	COG0477	Major facilitator Superfamily
MP622_01790	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MP622_01795	COG1597	lipid kinase activity
MP622_01800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MP622_01820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP622_01835	COG1196	nuclear chromosome segregation
MP622_01835	COG0741	lytic transglycosylase activity
MP622_01835	COG0739	heme binding
MP622_01840	COG0037	tRNA processing
MP622_01850	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MP622_01855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MP622_01865	COG1012	belongs to the aldehyde dehydrogenase family
MP622_01895	COG0006	proline dipeptidase activity
MP622_01900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_01905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MP622_01925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MP622_01930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MP622_01945	COG0792	nuclease activity
MP622_01970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MP622_01975	COG1388	LysM domain
MP622_01975	COG0741	lytic transglycosylase activity
MP622_01980	COG4166	transmembrane transport
MP622_01985	COG4174	ABC transporter (Permease)
MP622_01990	COG4239	(ABC) transporter, permease
MP622_01995	COG4172	Belongs to the ABC transporter superfamily
MP622_02025	COG0833	amino acid
MP622_02045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MP622_02050	COG0418	dihydroorotase activity
MP622_02060	COG1620	l-lactate permease
MP622_02065	COG2186	Transcriptional regulator
MP622_02075	COG0277	FAD linked oxidase domain protein
MP622_02080	COG0446	pyridine nucleotide-disulphide oxidoreductase
MP622_02080	COG1902	pentaerythritol trinitrate reductase activity
MP622_02100	COG1309	transcriptional regulator
MP622_02115	COG1053	succinate dehydrogenase
MP622_02120	COG0583	DNA-binding transcription factor activity
MP622_02135	COG0583	DNA-binding transcription factor activity
MP622_02150	COG0242	peptide deformylase activity
MP622_02160	COG2223	nitrite transmembrane transporter activity
MP622_02190	COG0306	phosphate transporter
MP622_02200	COG1215	transferase activity, transferring glycosyl groups
MP622_02205	COG1649	PFAM Uncharacterised BCR, COG1649
MP622_02205	COG0726	polysaccharide deacetylase
MP622_02210	COG0583	DNA-binding transcription factor activity
MP622_02220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MP622_02225	COG1773	rubredoxin
MP622_02230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MP622_02255	COG1741	Belongs to the pirin family
MP622_02265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MP622_02270	COG3739	integral membrane protein
MP622_02285	COG1393	Belongs to the ArsC family
MP622_02290	COG0640	Transcriptional regulator
MP622_02295	COG0798	PFAM Bile acid sodium symporter
MP622_02300	COG0431	NADPH-dependent FMN reductase
MP622_02305	COG0302	gtp cyclohydrolase
MP622_02325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MP622_02330	COG0512	Glutamine amidotransferase of anthranilate synthase
MP622_02335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MP622_02340	COG2249	NAD(P)H dehydrogenase (quinone) activity
MP622_02365	COG0523	cobalamin synthesis protein
MP622_02370	COG4681	YaeQ
MP622_02380	COG2203	Gaf domain
MP622_02380	COG2199	diguanylate cyclase activity
MP622_02455	COG4181	ATPase activity
MP622_02460	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MP622_02465	COG0705	Rhomboid family
MP622_02465	COG0457	Tetratricopeptide repeat
MP622_02470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MP622_02510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MP622_02515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MP622_02525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MP622_02525	COG3321	synthase
MP622_02525	COG0604	alcohol dehydrogenase
MP622_02525	COG4221	oxidoreductase activity
MP622_02540	COG1253	flavin adenine dinucleotide binding
MP622_02575	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MP622_02585	COG0280	phosphate acetyltransferase
MP622_02585	COG0281	malic enzyme
MP622_02595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MP622_02600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MP622_02605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MP622_02645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MP622_02650	COG0778	Nitroreductase
MP622_02655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MP622_02660	COG1051	belongs to the nudix hydrolase family
MP622_02660	COG1056	cytidyltransferase-related domain
MP622_02665	COG2353	YceI-like domain
MP622_02670	COG0583	DNA-binding transcription factor activity
MP622_02680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MP622_02695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MP622_02700	COG0602	queuosine metabolic process
MP622_02720	COG0583	DNA-binding transcription factor activity
MP622_02725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MP622_02730	COG4208	sulfate ABC transporter
MP622_02745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MP622_02750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MP622_02755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MP622_02775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MP622_02785	COG0481	GTPase activity
MP622_02790	COG0681	Belongs to the peptidase S26 family
MP622_02800	COG0571	ribonuclease III activity
MP622_02805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MP622_02820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MP622_02860	COG0436	Aminotransferase
MP622_02870	COG2199	diguanylate cyclase activity
MP622_02880	COG0556	nucleotide-excision repair
MP622_02910	COG1733	regulation of RNA biosynthetic process
MP622_02925	COG0671	phosphoesterase, PA-phosphatase related
MP622_02930	COG4772	TonB-dependent receptor
MP622_02940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MP622_02945	COG0076	glutamate decarboxylase activity
MP622_02950	COG1522	sequence-specific DNA binding
MP622_02955	COG3961	Belongs to the TPP enzyme family
MP622_02960	COG1113	amino acid transport
MP622_02965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MP622_02970	COG0573	inorganic phosphate transmembrane transporter activity
MP622_02980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MP622_02985	COG0616	signal peptide processing
MP622_03015	COG1335	isochorismatase
MP622_03020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MP622_03025	COG1686	Belongs to the peptidase S11 family
MP622_03040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MP622_03050	COG0583	DNA-binding transcription factor activity
MP622_03055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MP622_03060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MP622_03090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MP622_03115	COG2986	histidine ammonia-lyase
MP622_03155	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_03160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MP622_03175	COG2070	2-Nitropropane dioxygenase
MP622_03210	COG1067	ATP-dependent peptidase activity
MP622_03250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MP622_03255	COG1966	Carbon starvation protein
MP622_03260	COG2879	small protein
MP622_03265	COG0714	Associated with various cellular activities
MP622_03320	COG3646	Phage regulatory protein
MP622_03485	COG4695	Portal protein
MP622_03505	COG3646	Phage regulatory protein
MP622_03550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MP622_03770	COG2755	lipolytic protein G-D-S-L family
MP622_03770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MP622_03805	COG2252	PERMEase
MP622_03810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MP622_03815	COG3038	cytochrome b561
MP622_03830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MP622_03850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MP622_03870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MP622_03885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MP622_03900	COG0667	Aldo Keto reductase
MP622_03910	COG1765	OsmC-like protein
MP622_03940	COG1301	dicarboxylic acid transport
MP622_03945	COG0116	Belongs to the methyltransferase superfamily
MP622_03945	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MP622_03955	COG0540	Belongs to the ATCase OTCase family
MP622_03965	COG2885	chlorophyll binding
MP622_03965	COG3047	cAMP biosynthetic process
MP622_03985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MP622_03990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MP622_03990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MP622_03995	COG1254	Belongs to the acylphosphatase family
MP622_04045	COG4774	siderophore transport
MP622_04065	COG1113	amino acid transport
MP622_04075	COG0010	Belongs to the arginase family
MP622_04080	COG0546	phosphoglycolate phosphatase activity
MP622_04085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MP622_04090	COG0174	glutamine synthetase
MP622_04110	COG1944	ATP diphosphatase activity
MP622_04115	COG1252	NADH dehydrogenase
MP622_04125	COG2175	clavaminate synthase activity
MP622_04130	COG3246	L-lysine catabolic process to acetate
MP622_04150	COG2855	membrane
MP622_04175	COG0789	Transcriptional regulator
MP622_04190	COG0517	IMP dehydrogenase activity
MP622_04190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MP622_04195	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MP622_04205	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MP622_04210	COG1137	ATPase activity
MP622_04230	COG4122	O-methyltransferase activity
MP622_04240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MP622_04335	COG0583	DNA-binding transcription factor activity
MP622_04340	COG0477	Major facilitator Superfamily
MP622_04345	COG5002	protein histidine kinase activity
MP622_04345	COG3850	Histidine kinase
MP622_04370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP622_04380	COG1294	oxidase, subunit
MP622_04385	COG1271	oxidase subunit
MP622_04395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MP622_04405	COG1346	cytolysis
MP622_04415	COG3284	Transcriptional regulator
MP622_04440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MP622_04445	COG0235	Class ii aldolase
MP622_04450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP622_04460	COG3135	benzoate transporter
MP622_04465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP622_04470	COG2207	Transcriptional regulator
MP622_04485	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_04495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_04510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP622_04515	COG0183	Belongs to the thiolase family
MP622_04520	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MP622_04525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MP622_04535	COG4829	muconolactone delta-isomerase
MP622_04540	COG4948	Mandelate Racemase Muconate Lactonizing
MP622_04545	COG0583	DNA-binding transcription factor activity
MP622_04565	COG0154	amidase activity
MP622_04585	COG4638	Rieske (2fe-2S)
MP622_04595	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_04605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_04610	COG0543	2 iron, 2 sulfur cluster binding
MP622_04610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MP622_04615	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MP622_04620	COG4638	Rieske (2fe-2S)
MP622_04635	COG2204	response regulator
MP622_04645	COG3453	Protein conserved in bacteria
MP622_04645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MP622_04675	COG1022	Amp-dependent synthetase and ligase
MP622_04685	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_04690	COG1802	Transcriptional regulator
MP622_04755	COG1305	Transglutaminase-like
MP622_04770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MP622_04790	COG0360	Binds together with S18 to 16S ribosomal RNA
MP622_04795	COG0109	protoheme IX farnesyltransferase activity
MP622_04800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MP622_04805	COG1845	cytochrome c oxidase, subunit III
MP622_04810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MP622_04815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MP622_04840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MP622_04855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MP622_04860	COG2890	protein-(glutamine-N5) methyltransferase activity
MP622_04865	COG3781	membrane
MP622_04885	COG1960	acyl-CoA dehydrogenase activity
MP622_04890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MP622_04920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MP622_04930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MP622_04955	COG0729	surface antigen
MP622_04960	COG2911	Protein conserved in bacteria
MP622_04985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MP622_05035	COG0471	metal ion transport
MP622_05070	COG0308	aminopeptidase N
MP622_05100	COG3135	benzoate transporter
MP622_05110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MP622_05115	COG0583	DNA-binding transcription factor activity
MP622_05125	COG0586	Pfam SNARE associated Golgi protein
MP622_05130	COG0183	Belongs to the thiolase family
MP622_05135	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_05145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MP622_05155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MP622_05160	COG0824	Thioesterase
MP622_05165	COG1454	alcohol dehydrogenase
MP622_05170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MP622_05190	COG0069	glutamate synthase activity
MP622_05195	COG2197	response regulator
MP622_05200	COG4585	Histidine kinase
MP622_05205	COG2850	peptidyl-arginine hydroxylation
MP622_05210	COG0424	maF-like protein
MP622_05235	COG0697	spore germination
MP622_05250	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MP622_05260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MP622_05270	COG3698	Phosphodiester glycosidase
MP622_05285	COG0506	proline dehydrogenase activity
MP622_05285	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MP622_05285	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MP622_05295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MP622_05305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MP622_05335	COG0316	Belongs to the HesB IscA family
MP622_05340	COG0822	iron-sulfur transferase activity
MP622_05365	COG0776	regulation of translation
MP622_05370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MP622_05430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MP622_05450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MP622_05460	COG0133	tryptophan synthase activity
MP622_05465	COG0516	GMP reductase activity
MP622_05465	COG0517	IMP dehydrogenase activity
MP622_05490	COG0612	Peptidase, M16
MP622_05495	COG0552	protein localization to endoplasmic reticulum
MP622_05550	COG2814	Major facilitator Superfamily
MP622_05560	COG2199	diguanylate cyclase activity
MP622_05570	COG0439	Biotin carboxylase
MP622_05575	COG0511	ligase activity, forming carbon-carbon bonds
MP622_05620	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MP622_05625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MP622_05645	COG0583	DNA-binding transcription factor activity
MP622_05650	COG1960	acyl-CoA dehydrogenase activity
MP622_05700	COG0697	spore germination
MP622_05705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP622_05710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MP622_05715	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MP622_05730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MP622_05735	COG2814	Major facilitator Superfamily
MP622_05740	COG0509	glycine decarboxylation via glycine cleavage system
MP622_05755	COG1132	(ABC) transporter
MP622_05770	COG1280	lysine exporter protein (LysE YggA)
MP622_05780	COG0668	transmembrane transport
MP622_05785	COG3122	Protein conserved in bacteria
MP622_05805	COG0640	Transcriptional regulator
MP622_05810	COG2937	Belongs to the GPAT DAPAT family
MP622_05815	COG0596	Alpha beta hydrolase
MP622_05820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MP622_05825	COG1335	isochorismatase
MP622_05830	COG0251	oxidation-reduction process
MP622_05835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_05840	COG2233	PERMEase
MP622_05845	COG2084	Dehydrogenase
MP622_05850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MP622_05860	COG4770	biotin carboxylase activity
MP622_05865	COG1024	Enoyl-CoA hydratase
MP622_05870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MP622_05875	COG1960	acyl-CoA dehydrogenase activity
MP622_05880	COG1309	transcriptional regulator
MP622_05885	COG0318	PFAM AMP-dependent synthetase and ligase
MP622_05895	COG2226	methyltransferase
MP622_05905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MP622_05905	COG1116	anion transmembrane transporter activity
MP622_05915	COG2223	nitrite transmembrane transporter activity
MP622_05920	COG2146	nitrite reductase [NAD(P)H] activity
MP622_05920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MP622_05925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MP622_05930	COG0243	molybdopterin cofactor binding
MP622_05940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MP622_05955	COG0315	cyclic pyranopterin monophosphate synthase activity
MP622_05955	COG0521	Mo-molybdopterin cofactor biosynthetic process
MP622_05960	COG0303	'Molybdopterin
MP622_05965	COG0725	ABC transporter, periplasmic molybdate-binding protein
MP622_05970	COG4149	molybdate abc transporter
MP622_05975	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MP622_05985	COG0475	glutathione-regulated potassium exporter activity
MP622_05985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MP622_06005	COG1131	(ABC) transporter
MP622_06010	COG0842	Transport permease protein
MP622_06015	COG0842	Transport permease protein
MP622_06025	COG0583	DNA-binding transcription factor activity
MP622_06040	COG1280	lysine exporter protein (LysE YggA)
MP622_06065	COG1960	acyl-CoA dehydrogenase activity
MP622_06075	COG1012	belongs to the aldehyde dehydrogenase family
MP622_06080	COG1024	Enoyl-CoA hydratase
MP622_06085	COG2814	Major facilitator Superfamily
MP622_06100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MP622_06115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MP622_06150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MP622_06155	COG3138	arginine N-succinyltransferase
MP622_06160	COG1113	amino acid transport
MP622_06195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP622_06210	COG0019	diaminopimelate decarboxylase activity
MP622_06215	COG0318	PFAM AMP-dependent synthetase and ligase
MP622_06225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MP622_06230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MP622_06240	COG1846	Transcriptional regulator
MP622_06260	COG0583	DNA-binding transcription factor activity
MP622_06265	COG1538	Outer membrane efflux protein
MP622_06280	COG0583	DNA-binding transcription factor activity
MP622_06290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP622_06295	COG1773	rubredoxin
MP622_06335	COG0625	glutathione transferase activity
MP622_06345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MP622_06350	COG1473	amidohydrolase
MP622_06355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MP622_06360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MP622_06375	COG0765	amino acid transport
MP622_06380	COG1126	abc transporter atp-binding protein
MP622_06395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MP622_06400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MP622_06405	COG0022	dehydrogenase e1 component
MP622_06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
MP622_06415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MP622_06425	COG1063	alcohol dehydrogenase
MP622_06445	COG4628	conserved protein (DUF2132)
MP622_06450	COG1309	transcriptional regulator
MP622_06455	COG0604	alcohol dehydrogenase
MP622_06460	COG0596	Alpha beta hydrolase
MP622_06480	COG0583	DNA-binding transcription factor activity
MP622_06485	COG1380	Effector of murein hydrolase LrgA
MP622_06490	COG1346	cytolysis
MP622_06505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MP622_06520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MP622_06535	COG1278	Cold shock
MP622_06555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MP622_06560	COG2267	carboxylic ester hydrolase activity
MP622_06565	COG2453	phosphatase
MP622_06565	COG0671	phosphoesterase, PA-phosphatase related
MP622_06580	COG4589	Belongs to the CDS family
MP622_06615	COG0542	response to heat
MP622_06620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MP622_06635	COG3706	GGDEF domain
MP622_06645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MP622_06650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MP622_06660	COG0569	domain protein
MP622_06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MP622_06685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MP622_06695	COG1585	Membrane protein implicated in regulation of membrane protease activity
MP622_06710	COG1294	oxidase, subunit
MP622_06715	COG4890	Cyd operon protein YbgT
MP622_06750	COG1960	acyl-CoA dehydrogenase activity
MP622_06755	COG1960	acyl-CoA dehydrogenase activity
MP622_06760	COG0456	acetyltransferase
MP622_06765	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP622_06770	COG2207	Transcriptional regulator
MP622_06775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MP622_06780	COG4773	Receptor
MP622_06800	COG0730	response to heat
MP622_06805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MP622_06830	COG0772	Belongs to the SEDS family
MP622_06845	COG0148	phosphopyruvate hydratase activity
MP622_06880	COG1902	pentaerythritol trinitrate reductase activity
MP622_06880	COG0446	pyridine nucleotide-disulphide oxidoreductase
MP622_06895	COG0583	DNA-binding transcription factor activity
MP622_06900	COG4948	Mandelate Racemase Muconate Lactonizing
MP622_06905	COG4829	muconolactone delta-isomerase
MP622_06915	COG4638	Rieske (2fe-2S)
MP622_06920	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MP622_06925	COG0633	Ferredoxin
MP622_06925	COG0543	2 iron, 2 sulfur cluster binding
MP622_06930	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_06935	COG3135	benzoate transporter
MP622_06940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MP622_06945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MP622_06950	COG0183	Belongs to the thiolase family
MP622_06955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP622_06965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MP622_06970	COG1960	acyl-CoA dehydrogenase activity
MP622_06975	COG0583	DNA-binding transcription factor activity
MP622_06980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MP622_06990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MP622_06995	COG0702	epimerase
MP622_07020	COG1011	Hydrolase
MP622_07025	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MP622_07030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MP622_07035	COG2137	regulation of response to DNA damage stimulus
MP622_07050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MP622_07085	COG0575	Belongs to the CDS family
MP622_07090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MP622_07110	COG3852	Histidine kinase
MP622_07125	COG0583	DNA-binding transcription factor activity
MP622_07130	COG0024	Methionine aminopeptidase
MP622_07155	COG1253	flavin adenine dinucleotide binding
MP622_07170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MP622_07175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MP622_07185	COG2431	L-lysine efflux transmembrane transporter activity
MP622_07265	COG1309	transcriptional regulator
MP622_07270	COG0084	hydrolase, TatD family'
MP622_07290	COG1663	tetraacyldisaccharide 4'-kinase activity
MP622_07295	COG1132	(ABC) transporter
MP622_07305	COG0811	peptide transport
MP622_07310	COG1475	DNA binding
MP622_07315	COG1192	Involved in chromosome partitioning
MP622_07320	COG0357	Ribosomal RNA small subunit methyltransferase G
MP622_07325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MP622_07330	COG3178	'Phosphotransferase
MP622_07340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MP622_07345	COG1923	regulation of RNA biosynthetic process
MP622_07355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MP622_07360	COG0802	atpase or kinase
MP622_07385	COG2707	UPF0756 membrane protein
MP622_07390	COG0583	DNA-binding transcription factor activity
MP622_07395	COG2814	Major facilitator Superfamily
MP622_07400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MP622_07405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MP622_07415	COG1454	alcohol dehydrogenase
MP622_07435	COG0697	spore germination
MP622_07460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MP622_07460	COG0519	Catalyzes the synthesis of GMP from XMP
MP622_07470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MP622_07505	COG0515	serine threonine protein kinase
MP622_07505	COG2815	serine threonine protein kinase
MP622_07545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MP622_07555	COG1610	YqeY-like protein
MP622_07570	COG4783	chaperone-mediated protein folding
MP622_07625	COG0778	Nitroreductase
MP622_07635	COG0513	Belongs to the DEAD box helicase family
MP622_07655	COG2363	Small membrane protein
MP622_07675	COG0625	glutathione transferase activity
MP622_07685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MP622_07705	COG4772	TonB-dependent receptor
MP622_07710	COG4993	Dehydrogenase
MP622_07715	COG3659	wide pore channel activity
MP622_07720	COG3420	alginic acid biosynthetic process
MP622_07725	COG0710	3-dehydroquinate dehydratase activity
MP622_07730	COG3485	protocatechuate 3,4-dioxygenase
MP622_07735	COG3485	protocatechuate 3,4-dioxygenase
MP622_07740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MP622_07745	COG2271	Major facilitator Superfamily
MP622_07750	COG0596	Alpha beta hydrolase
MP622_07755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MP622_07760	COG0183	Belongs to the thiolase family
MP622_07765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MP622_07770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MP622_07775	COG1414	Transcriptional regulator
MP622_07780	COG0531	amino acid
MP622_07785	COG0646	methionine synthase
MP622_07785	COG1410	methionine synthase
MP622_07820	COG0864	Transcriptional regulator
MP622_07825	COG0439	Biotin carboxylase
MP622_07840	COG3706	GGDEF domain
MP622_07845	COG2814	Major facilitator Superfamily
MP622_07855	COG0445	tRNA wobble uridine modification
MP622_07880	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MP622_07885	COG0138	bifunctional purine biosynthesis protein purh
MP622_07890	COG0151	Belongs to the GarS family
MP622_07900	COG1250	3-hydroxyacyl-CoA dehydrogenase
MP622_07905	COG1464	Belongs to the NlpA lipoprotein family
MP622_07910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MP622_07915	COG2011	ABC-type metal ion transport system permease component
MP622_07935	COG1045	serine acetyltransferase
MP622_07950	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_07955	COG2909	trisaccharide binding
MP622_07965	COG0318	PFAM AMP-dependent synthetase and ligase
MP622_07970	COG0300	oxidoreductase activity
MP622_07975	COG0300	oxidoreductase activity
MP622_07985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MP622_07990	COG1309	transcriptional regulator
MP622_07995	COG1012	belongs to the aldehyde dehydrogenase family
MP622_08010	COG0579	oxidoreductase
MP622_08055	COG1012	belongs to the aldehyde dehydrogenase family
MP622_08060	COG0531	amino acid
MP622_08065	COG0531	amino acid
MP622_08070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MP622_08075	COG0204	Acyl-transferase
MP622_08110	COG1464	Belongs to the NlpA lipoprotein family
MP622_08115	COG1464	Belongs to the NlpA lipoprotein family
MP622_08120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MP622_08125	COG2011	ABC-type metal ion transport system permease component
MP622_08130	COG0012	GTP binding
MP622_08135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MP622_08155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MP622_08165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MP622_08190	COG1917	Cupin 2, conserved barrel domain protein
MP622_08190	COG2207	Transcriptional regulator
MP622_08195	COG0386	Belongs to the glutathione peroxidase family
MP622_08200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MP622_08205	COG0436	Aminotransferase
MP622_08210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MP622_08245	COG0612	Peptidase, M16
MP622_08250	COG0384	phenazine biosynthesis protein PhzF
MP622_08255	COG1823	symporter activity
MP622_08260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_08280	COG0753	catalase activity
MP622_08300	COG2050	protein possibly involved in aromatic compounds catabolism
MP622_08305	COG2351	hydroxyisourate hydrolase activity
MP622_08315	COG1686	Belongs to the peptidase S11 family
MP622_08320	COG1252	NADH dehydrogenase
MP622_08330	COG0415	Belongs to the DNA photolyase family
MP622_08360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MP622_08370	COG0693	protein deglycase activity
MP622_08375	COG1960	acyl-CoA dehydrogenase activity
MP622_08380	COG1301	dicarboxylic acid transport
MP622_08390	COG3139	Protein of unknown function (DUF1315)
MP622_08395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MP622_08400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MP622_08420	COG0642	Histidine kinase
MP622_08440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MP622_08450	COG2203	Gaf domain
MP622_08450	COG2199	diguanylate cyclase activity
MP622_08455	COG1720	tRNA m6t6A37 methyltransferase activity
MP622_08495	COG0826	peptidase U32
MP622_08500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MP622_08505	COG3634	alkyl hydroperoxide reductase activity
MP622_08535	COG1643	Atp-dependent helicase
MP622_08580	COG0564	pseudouridine synthase activity
MP622_08595	COG0352	thiamine-phosphate diphosphorylase activity
MP622_08600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MP622_08635	COG2814	Major facilitator Superfamily
MP622_08680	COG1136	(ABC) transporter
MP622_08690	COG3038	cytochrome b561
MP622_08695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MP622_08715	COG2816	NAD+ diphosphatase activity
MP622_08730	COG1131	(ABC) transporter
MP622_08735	COG0842	Transport permease protein
MP622_08750	COG0772	Belongs to the SEDS family
MP622_08755	COG2951	lytic endotransglycosylase activity
MP622_08800	COG0052	Belongs to the universal ribosomal protein uS2 family
MP622_08815	COG2223	nitrite transmembrane transporter activity
MP622_08830	COG2175	clavaminate synthase activity
MP622_08835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MP622_08840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MP622_08860	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_08865	COG2610	gluconate transmembrane transporter activity
MP622_08870	COG0583	DNA-binding transcription factor activity
MP622_08880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MP622_08905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MP622_08905	COG0047	phosphoribosylformylglycinamidine synthase activity
MP622_08920	COG2255	four-way junction helicase activity
MP622_08935	COG0824	Thioesterase
MP622_08955	COG0823	Involved in the tonB-independent uptake of proteins
MP622_08975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MP622_09005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MP622_09010	COG0628	permease
MP622_09020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MP622_09040	COG0658	competence protein
MP622_09040	COG2333	competence protein COMEC
MP622_09045	COG1136	(ABC) transporter
MP622_09050	COG4591	ABC-type transport system involved in lipoprotein release permease component
MP622_09060	COG0697	spore germination
MP622_09065	COG1671	Belongs to the UPF0178 family
MP622_09090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP622_09105	COG1301	dicarboxylic acid transport
MP622_09130	COG1280	lysine exporter protein (LysE YggA)
MP622_09135	COG1522	sequence-specific DNA binding
MP622_09150	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MP622_09165	COG0019	diaminopimelate decarboxylase activity
MP622_09175	COG1113	amino acid transport
MP622_09180	COG1115	amino acid carrier protein
MP622_09205	COG0175	sulfate reduction
MP622_09220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MP622_09235	COG0174	glutamine synthetase
MP622_09360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MP622_09375	COG1802	Transcriptional regulator
MP622_09380	COG2217	Heavy metal translocating P-type atpase
MP622_09390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MP622_09405	COG2234	aminopeptidase activity
MP622_09415	COG3384	dioxygenase
MP622_09425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MP622_09430	COG2878	Part of a membrane complex involved in electron transport
MP622_09435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MP622_09460	COG0768	penicillin binding
MP622_09465	COG0742	ribosomal rna small subunit methyltransferase
MP622_09495	COG0583	DNA-binding transcription factor activity
MP622_09500	COG2814	Major facilitator Superfamily
MP622_09510	COG1607	acyl-coa hydrolase
MP622_09515	COG1752	Esterase of the alpha-beta hydrolase superfamily
MP622_09520	COG1115	amino acid carrier protein
MP622_09525	COG0786	glutamate:sodium symporter activity
MP622_09540	COG2321	neutral zinc metallopeptidase
MP622_09545	COG2354	Protein conserved in bacteria
MP622_09555	COG1585	Membrane protein implicated in regulation of membrane protease activity
MP622_09560	COG2268	Band 7 protein
MP622_09580	COG3733	amine oxidase
MP622_09590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MP622_09600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MP622_09615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MP622_09620	COG1053	succinate dehydrogenase
MP622_09625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MP622_09630	COG2009	succinate dehydrogenase
MP622_09640	COG2072	flavoprotein involved in K transport
MP622_09645	COG0300	oxidoreductase activity
MP622_09660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MP622_09660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MP622_09680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MP622_09705	COG0564	pseudouridine synthase activity
MP622_09730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MP622_09760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MP622_09780	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MP622_09785	COG1280	lysine exporter protein (LysE YggA)
MP622_09805	COG0586	Pfam SNARE associated Golgi protein
MP622_09835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MP622_09840	COG2921	Belongs to the UPF0250 family
MP622_09845	COG0321	lipoyl(octanoyl) transferase activity
MP622_09860	COG0531	amino acid
MP622_09870	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_09880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MP622_09885	COG1648	precorrin-2 dehydrogenase activity
MP622_09885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MP622_09890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MP622_09900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MP622_09910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MP622_09930	COG0671	phosphoesterase, PA-phosphatase related
MP622_09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP622_09945	COG1538	Outer membrane efflux protein
MP622_09950	COG0393	Putative heavy-metal-binding
MP622_09965	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_09975	COG0525	valine-tRNA ligase activity
MP622_09995	COG0765	amino acid transport
MP622_10000	COG0765	amino acid transport
MP622_10005	COG1126	abc transporter atp-binding protein
MP622_10010	COG0004	ammonium transporteR
MP622_10015	COG1011	Hydrolase
MP622_10025	COG0642	Histidine kinase
MP622_10030	COG0745	RESPONSE REGULATOR receiver
MP622_10035	COG2194	sulfuric ester hydrolase activity
MP622_10045	COG2814	Major facilitator Superfamily
MP622_10055	COG1752	Esterase of the alpha-beta hydrolase superfamily
MP622_10070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MP622_10075	COG0142	geranyltranstransferase activity
MP622_10080	COG2199	diguanylate cyclase activity
MP622_10085	COG2828	Protein conserved in bacteria
MP622_10090	COG1113	amino acid transport
MP622_10100	COG0582	viral genome integration into host DNA
MP622_10130	COG2814	Major facilitator Superfamily
MP622_10170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MP622_10185	COG2205	protein histidine kinase activity
MP622_10250	COG0745	RESPONSE REGULATOR receiver
MP622_10255	COG2205	protein histidine kinase activity
MP622_10260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MP622_10265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MP622_10270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MP622_10275	COG0235	Class ii aldolase
MP622_10280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MP622_10290	COG4716	Myosin-crossreactive antigen
MP622_10315	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MP622_10320	COG2081	HI0933 family
MP622_10335	COG0668	transmembrane transport
MP622_10345	COG4303	Ethanolamine ammonia lyase large subunit
MP622_10350	COG0531	amino acid
MP622_10365	COG0583	DNA-binding transcription factor activity
MP622_10370	COG1278	Cold shock
MP622_10390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MP622_10395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MP622_10400	COG0713	ATP synthesis coupled electron transport
MP622_10410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MP622_10425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MP622_10435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MP622_10435	COG0649	NAD binding
MP622_10455	COG2205	protein histidine kinase activity
MP622_10460	COG0745	RESPONSE REGULATOR receiver
MP622_10465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MP622_10465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MP622_10480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MP622_10495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP622_10500	COG2274	protein secretion by the type I secretion system
MP622_10515	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_10530	COG1399	metal-binding, possibly nucleic acid-binding protein
MP622_10535	COG3101	peptidyl-lysine hydroxylation
MP622_10540	COG0009	L-threonylcarbamoyladenylate synthase
MP622_10545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MP622_10550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MP622_10565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MP622_10585	COG4166	transmembrane transport
MP622_10625	COG2226	methyltransferase
MP622_10635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MP622_10635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MP622_10640	COG0596	Alpha beta hydrolase
MP622_10640	COG2226	methyltransferase
MP622_10640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP622_10645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MP622_10660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MP622_10665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MP622_10675	COG1196	nuclear chromosome segregation
MP622_10685	COG0730	response to heat
MP622_10705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MP622_10735	COG0789	Transcriptional regulator
MP622_10745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MP622_10755	COG3422	double-strand break repair
MP622_10765	COG2824	Alkylphosphonate utilization operon protein PhnA
MP622_10775	COG3189	MarR family transcriptional regulator
MP622_10795	COG0564	pseudouridine synthase activity
MP622_10830	COG0354	folic acid binding
MP622_10855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MP622_10870	COG0424	maF-like protein
MP622_10875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MP622_10880	COG1792	Involved in formation and maintenance of cell shape
MP622_10885	COG1077	Cell shape determining protein MreB Mrl
MP622_10890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MP622_10900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MP622_10920	COG0583	DNA-binding transcription factor activity
MP622_10955	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MP622_10970	COG0679	Auxin Efflux Carrier
MP622_10975	COG1902	pentaerythritol trinitrate reductase activity
MP622_10995	COG1970	mechanosensitive ion channel activity
MP622_11000	COG1217	gtp-binding protein TYPA
MP622_11005	COG2233	PERMEase
MP622_11010	COG2813	Specifically methylates the guanine in position
MP622_11015	COG0833	amino acid
MP622_11045	COG0183	Belongs to the thiolase family
MP622_11065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MP622_11080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MP622_11085	COG2207	Transcriptional regulator
MP622_11090	COG0183	Belongs to the thiolase family
MP622_11115	COG1272	protein, Hemolysin III
MP622_11120	COG0477	Major facilitator Superfamily
MP622_11125	COG1408	metallophosphoesterase
MP622_11130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MP622_11145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MP622_11170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MP622_11175	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MP622_11185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MP622_11190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MP622_11195	COG0625	glutathione transferase activity
MP622_11200	COG2969	positive regulation of protein catabolic process
MP622_11260	COG2199	diguanylate cyclase activity
MP622_11290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MP622_11295	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MP622_11310	COG0450	alkyl hydroperoxide reductase
MP622_11330	COG0285	dihydrofolate synthase activity
MP622_11335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MP622_11380	COG4206	TonB-dependent receptor
MP622_11385	COG2096	Adenosyltransferase
MP622_11400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MP622_11405	COG2315	Protein conserved in bacteria
MP622_11410	COG1113	amino acid transport
MP622_11415	COG0745	RESPONSE REGULATOR receiver
MP622_11420	COG2205	protein histidine kinase activity
MP622_11430	COG1960	acyl-CoA dehydrogenase activity
MP622_11435	COG1960	acyl-CoA dehydrogenase activity
MP622_11440	COG3223	Belongs to the PsiE family
MP622_11470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MP622_11505	COG1091	dTDP-4-dehydrorhamnose reductase activity
MP622_11525	COG0726	polysaccharide deacetylase
MP622_11540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MP622_11545	COG5002	protein histidine kinase activity
MP622_11550	COG3706	GGDEF domain
MP622_11560	COG0793	Belongs to the peptidase S41A family
MP622_11590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MP622_11595	COG0857	belongs to the CobB CobQ family
MP622_11595	COG0280	phosphate acetyltransferase
MP622_11600	COG2226	methyltransferase
MP622_11615	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MP622_11615	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MP622_11635	COG0740	serine-type endopeptidase activity
MP622_11645	COG4771	TonB-dependent receptor
MP622_11650	COG4774	siderophore transport
MP622_11660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MP622_11670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MP622_11670	COG2813	Specifically methylates the guanine in position
MP622_11780	COG0788	formyltetrahydrofolate deformylase activity
MP622_11805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MP622_11805	COG4651	solute:proton antiporter activity
MP622_11825	COG0724	RNA recognition motif
MP622_11830	COG0210	DNA helicase
MP622_11835	COG1929	Belongs to the glycerate kinase type-1 family
MP622_11870	COG2900	Belongs to the SlyX family
MP622_11875	COG0488	(ABC) transporter
MP622_11890	COG1560	Kdo2-lipid A biosynthetic process
MP622_11920	COG0252	asparaginase activity
MP622_11945	COG0473	3-isopropylmalate dehydrogenase activity
MP622_12005	COG1846	Transcriptional regulator
MP622_12015	COG1960	acyl-CoA dehydrogenase activity
MP622_12025	COG1280	lysine exporter protein (LysE YggA)
MP622_12035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MP622_12040	COG3011	Protein conserved in bacteria
MP622_12055	COG0446	pyridine nucleotide-disulphide oxidoreductase
MP622_12060	COG3384	dioxygenase
MP622_12065	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_12080	COG4638	Rieske (2fe-2S)
MP622_12085	COG0583	DNA-binding transcription factor activity
MP622_12110	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MP622_12115	COG3971	2-oxopent-4-enoate hydratase activity
MP622_12120	COG0625	glutathione transferase activity
MP622_12125	COG2378	regulation of single-species biofilm formation
MP622_12130	COG0546	phosphoglycolate phosphatase activity
MP622_12140	COG1530	ribonuclease E activity
MP622_12145	COG0318	PFAM AMP-dependent synthetase and ligase
MP622_12175	COG1983	PspC domain protein
MP622_12180	COG0617	tRNA 3'-terminal CCA addition
MP622_12180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MP622_12180	COG0517	IMP dehydrogenase activity
MP622_12195	COG0751	glycine-tRNA ligase activity
MP622_12225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MP622_12255	COG0493	'glutamate synthase
MP622_12265	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MP622_12280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MP622_12295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MP622_12305	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MP622_12305	COG0644	oxidoreductase
MP622_12320	COG4535	Mg2 and Co2 transporter CorC
MP622_12325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MP622_12345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MP622_12355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MP622_12365	COG0484	heat shock protein binding
MP622_12370	COG0789	Transcriptional regulator
MP622_12375	COG2841	Protein conserved in bacteria
MP622_12380	COG0598	Magnesium transport protein CorA
MP622_12390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MP622_12395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MP622_12400	COG1074	ATP-dependent DNA helicase activity
MP622_12405	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MP622_12425	COG2226	methyltransferase
MP622_12435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MP622_12445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MP622_12460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MP622_12460	COG2111	Na H antiporter
MP622_12465	COG1006	Multisubunit Na H antiporter MnhC subunit
MP622_12470	COG0651	ATP synthesis coupled electron transport
MP622_12475	COG1863	multisubunit Na H antiporter MnhE subunit
MP622_12480	COG2212	antiporter activity
MP622_12485	COG1320	monovalent cation:proton antiporter activity
MP622_12490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MP622_12495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MP622_12500	COG0195	Participates in both transcription termination and antitermination
MP622_12505	COG0779	Required for maturation of 30S ribosomal subunits
MP622_12555	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MP622_12560	COG0237	dephospho-CoA kinase activity
MP622_12570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MP622_12575	COG3123	guanosine phosphorylase activity
MP622_12580	COG0497	DNA recombination
MP622_12590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MP622_12605	COG1289	transmembrane transporter activity
MP622_12615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MP622_12630	COG1733	regulation of RNA biosynthetic process
MP622_12685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MP622_12715	COG0326	Molecular chaperone. Has ATPase activity
MP622_12730	COG2056	Na+-H+ antiporter family
MP622_12775	COG0081	regulation of translation
MP622_12800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MP622_12830	COG0546	phosphoglycolate phosphatase activity
MP622_12835	COG1716	ATPase activity
MP622_12860	COG0824	Thioesterase
MP622_12880	COG0181	hydroxymethylbilane synthase activity
MP622_12890	COG3275	phosphorelay sensor kinase activity
MP622_12910	COG1538	Outer membrane efflux protein
MP622_12925	COG0494	nUDIX hydrolase
MP622_12930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MP622_12935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MP622_12940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MP622_12945	COG0772	Belongs to the SEDS family
MP622_12970	COG4974	Belongs to the 'phage' integrase family
MP622_12975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MP622_12985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MP622_13000	COG1686	Belongs to the peptidase S11 family
MP622_13005	COG2197	response regulator
MP622_13010	COG3852	Histidine kinase
MP622_13020	COG0793	Belongs to the peptidase S41A family
MP622_13025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MP622_13030	COG0795	lipopolysaccharide-transporting ATPase activity
MP622_13035	COG0795	lipopolysaccharide-transporting ATPase activity
MP622_13060	COG0586	Pfam SNARE associated Golgi protein
MP622_13075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MP622_13075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MP622_13085	COG0004	ammonium transporteR
MP622_13090	COG0347	Belongs to the P(II) protein family
MP622_13100	COG0606	chelatase, subunit chli
MP622_13115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MP622_13130	COG0318	PFAM AMP-dependent synthetase and ligase
MP622_13140	COG0477	Major facilitator Superfamily
MP622_13145	COG2860	membrane
MP622_13155	COG1253	flavin adenine dinucleotide binding
MP622_13170	COG0477	Major facilitator Superfamily
MP622_13180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MP622_13200	COG2814	Major facilitator Superfamily
MP622_13255	COG1652	LysM domain
MP622_13260	COG0758	DNA mediated transformation
MP622_13270	COG0697	spore germination
MP622_13280	COG0386	Belongs to the glutathione peroxidase family
MP622_13315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MP622_13325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MP622_13365	COG1121	(ABC) transporter
MP622_13370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MP622_13380	COG2837	iron assimilation
MP622_13410	COG0281	malic enzyme
MP622_13465	COG0519	Catalyzes the synthesis of GMP from XMP
MP622_13465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MP622_13470	COG2259	Doxx family
MP622_13475	COG0586	Pfam SNARE associated Golgi protein
MP622_13490	COG1192	Involved in chromosome partitioning
MP622_13500	COG0271	Belongs to the BolA IbaG family
MP622_13520	COG1113	amino acid transport
MP622_13530	COG3724	N-succinylarginine dihydrolase activity
MP622_13535	COG1012	belongs to the aldehyde dehydrogenase family
MP622_13550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MP622_13565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MP622_13570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MP622_13580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MP622_13590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MP622_13595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MP622_13600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MP622_13615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MP622_13630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MP622_13640	COG1215	transferase activity, transferring glycosyl groups
MP622_13650	COG0438	transferase activity, transferring glycosyl groups
MP622_13660	COG1596	polysaccharide export
MP622_13675	COG0166	Belongs to the GPI family
MP622_13685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MP622_13690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MP622_13710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MP622_13745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MP622_13750	COG1596	polysaccharide export
MP622_13775	COG0728	peptidoglycan biosynthetic process
MP622_13800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MP622_13815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MP622_13820	COG0546	phosphoglycolate phosphatase activity
MP622_13825	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_13845	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MP622_13845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MP622_13850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MP622_13855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MP622_13860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MP622_13865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MP622_13870	COG1116	anion transmembrane transporter activity
MP622_13875	COG1309	transcriptional regulator
MP622_13880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MP622_13890	COG0196	riboflavin kinase activity
MP622_13895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MP622_13905	COG1047	Peptidyl-prolyl cis-trans
MP622_13925	COG0129	dihydroxy-acid dehydratase activity
MP622_13940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MP622_13940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MP622_13945	COG0428	transporter
MP622_13955	COG0733	neurotransmitter:sodium symporter activity
MP622_14010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MP622_14015	COG0657	acetylesterase activity
MP622_14030	COG0583	DNA-binding transcription factor activity
MP622_14055	COG2951	lytic endotransglycosylase activity
MP622_14060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MP622_14075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MP622_14090	COG0861	Integral membrane protein TerC family
MP622_14095	COG0402	S-adenosylhomocysteine deaminase activity
MP622_14110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MP622_14115	COG1230	cation diffusion facilitator family transporter
MP622_14130	COG2226	methyltransferase
MP622_14140	COG0706	membrane insertase activity
MP622_14145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MP622_14160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MP622_14165	COG0592	DNA-directed DNA polymerase activity
MP622_14175	COG0187	DNA topoisomerase II activity
MP622_14185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MP622_14190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MP622_14215	COG0488	(ABC) transporter
MP622_14250	COG2814	Major facilitator Superfamily
MP622_14255	COG2133	pyrroloquinoline quinone binding
MP622_14270	COG2233	PERMEase
MP622_14285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP622_14310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MP622_14320	COG2814	Major facilitator Superfamily
MP622_14325	COG0656	L-ascorbic acid biosynthetic process
MP622_14330	COG0583	DNA-binding transcription factor activity
MP622_14340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MP622_14345	COG1064	alcohol dehydrogenase
MP622_14350	COG2818	Glycosylase
MP622_14365	COG1194	a g-specific adenine glycosylase
MP622_14380	COG5487	UPF0391 membrane protein
MP622_14385	COG2983	Belongs to the UPF0260 family
MP622_14390	COG2819	hydrolase of the alpha beta superfamily
MP622_14395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MP622_14405	COG4160	amino acid transport
MP622_14425	COG1522	sequence-specific DNA binding
MP622_14430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MP622_14440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MP622_14445	COG2814	Major facilitator Superfamily
MP622_14450	COG1335	isochorismatase
MP622_14455	COG0385	Bile acid
MP622_14470	COG0560	Phosphoserine phosphatase
MP622_14470	COG3830	Belongs to the UPF0237 family
MP622_14535	COG0534	Mate efflux family protein
MP622_14540	COG0436	Aminotransferase
MP622_14545	COG2733	membrane
MP622_14560	COG2918	glutathione biosynthetic process
MP622_14565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MP622_14575	COG3150	esterase
MP622_14635	COG0666	response to abiotic stimulus
MP622_14635	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MP622_14655	COG3706	GGDEF domain
MP622_14660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MP622_14680	COG0708	Exodeoxyribonuclease III
MP622_14685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MP622_14720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MP622_14730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MP622_14765	COG0508	dehydrogenase complex catalyzes the overall conversion of
MP622_14775	COG2119	membrane
MP622_14780	COG0426	domain, Protein
MP622_14780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_14800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MP622_14825	COG1902	pentaerythritol trinitrate reductase activity
MP622_14830	COG1519	Transferase
MP622_14835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MP622_14840	COG0668	transmembrane transport
MP622_14850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MP622_14865	COG0431	NADPH-dependent FMN reductase
MP622_14880	COG2198	Histidine kinase
MP622_14880	COG2205	protein histidine kinase activity
MP622_14880	COG0784	Response regulator, receiver
MP622_14885	COG3162	membrane
MP622_14900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MP622_14915	COG3706	GGDEF domain
MP622_14930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MP622_14935	COG1309	transcriptional regulator
MP622_14940	COG1063	alcohol dehydrogenase
MP622_14960	COG0300	oxidoreductase activity
MP622_14965	COG0789	Transcriptional regulator
MP622_14970	COG0351	phosphomethylpyrimidine kinase
MP622_14970	COG0352	thiamine-phosphate diphosphorylase activity
MP622_14970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MP622_14980	COG2814	Major facilitator Superfamily
MP622_14985	COG0629	single-stranded DNA binding
MP622_14990	COG1113	amino acid transport
MP622_15000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MP622_15005	COG1012	belongs to the aldehyde dehydrogenase family
MP622_15020	COG1335	isochorismatase
MP622_15030	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MP622_15050	COG2814	Major facilitator Superfamily
MP622_15055	COG0583	DNA-binding transcription factor activity
MP622_15080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MP622_15085	COG1960	acyl-CoA dehydrogenase activity
MP622_15090	COG1024	Enoyl-CoA hydratase
MP622_15130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MP622_15150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MP622_15170	COG0531	amino acid
MP622_15175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MP622_15195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MP622_15205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MP622_15240	COG0427	acetyl-CoA hydrolase
MP622_15265	COG4221	oxidoreductase activity
MP622_15270	COG2873	o-acetylhomoserine
MP622_15275	COG0488	(ABC) transporter
MP622_15345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MP622_15350	COG0275	rRNA processing
MP622_15365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MP622_15370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MP622_15380	COG2226	methyltransferase
MP622_15430	COG0067	glutamate synthase
MP622_15430	COG0069	glutamate synthase activity
MP622_15430	COG0070	glutamate synthase
MP622_15435	COG0493	'glutamate synthase
MP622_15445	COG1704	LemA family
MP622_15450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MP622_15485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MP622_15500	COG1028	Short-chain dehydrogenase reductase Sdr
MP622_15505	COG3307	-O-antigen
MP622_15525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MP622_15530	COG1758	RNA polymerase activity
MP622_15535	COG0194	GDP metabolic process
MP622_15575	COG4969	Belongs to the N-Me-Phe pilin family
MP622_15580	COG0228	four-way junction DNA binding
MP622_15585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MP622_15595	COG0335	large ribosomal subunit rRNA binding
MP622_15600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MP622_15605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MP622_15610	COG5380	lipid catabolic process
MP622_15615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MP622_15635	COG5006	permease, DMT superfamily
MP622_15640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MP622_15645	COG0277	FAD linked oxidase domain protein
MP622_15655	COG2197	response regulator
MP622_15660	COG0477	Major facilitator Superfamily
MP622_15670	COG2814	Major facilitator Superfamily
MP622_15675	COG1289	transmembrane transporter activity
MP622_15680	COG2032	superoxide dismutase activity
MP622_15685	COG0628	permease
MP622_15690	COG1192	Involved in chromosome partitioning
MP622_15700	COG2226	methyltransferase
MP622_15715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MP622_15725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MP622_15730	COG0534	Mate efflux family protein
MP622_15740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MP622_15750	COG1960	acyl-CoA dehydrogenase activity
MP622_15770	COG0408	coproporphyrinogen oxidase activity
MP622_15775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MP622_15795	COG0513	Belongs to the DEAD box helicase family
MP622_15800	COG1127	ABC transporter
MP622_15805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MP622_15810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MP622_15825	COG0598	Magnesium transport protein CorA
MP622_15840	COG1040	competence protein
MP622_15845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MP622_15880	COG2937	Belongs to the GPAT DAPAT family
MP622_15885	COG1946	Acyl-CoA thioesterase
MP622_15890	COG1301	dicarboxylic acid transport
MP622_15910	COG1959	2 iron, 2 sulfur cluster binding
MP622_15920	COG0433	COG0433 Predicted ATPase
MP622_15925	COG0626	cystathionine gamma-synthase activity
MP622_15945	COG0088	Forms part of the polypeptide exit tunnel
MP622_15950	COG0089	rRNA binding
MP622_15960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MP622_16000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MP622_16010	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MP622_16015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MP622_16025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MP622_16050	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MP622_16060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MP622_16070	COG0203	ribosomal protein L17
MP622_16075	COG2072	flavoprotein involved in K transport
MP622_16080	COG1960	acyl-CoA dehydrogenase activity
MP622_16085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MP622_16125	COG0339	signal peptide processing
MP622_16135	COG0557	exoribonuclease II activity
MP622_16170	COG0179	Fumarylacetoacetate (FAA) hydrolase
MP622_16200	COG1295	ribonuclease BN
MP622_16245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MP622_16250	COG1702	phosphate starvation-inducible protein PhoH
MP622_16260	COG0739	heme binding
MP622_16260	COG0741	lytic transglycosylase activity
MP622_16260	COG1196	nuclear chromosome segregation
MP622_16295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MP622_16300	COG1183	phosphatidylcholine synthase activity
MP622_16340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MP622_16370	COG1607	acyl-coa hydrolase
MP622_16380	COG1666	GTP binding
MP622_16400	COG2350	Protein conserved in bacteria
MP622_16410	COG0613	PHP domain protein
MP622_16415	COG0625	glutathione transferase activity
MP622_16420	COG3781	membrane
MP622_16425	COG2003	Belongs to the UPF0758 family
MP622_16430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MP622_16435	COG3783	Cytochrome b(562)
MP622_16465	COG1162	GTPase activity
MP622_16470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MP622_16485	COG1538	Outer membrane efflux protein
MP622_16490	COG1136	(ABC) transporter
MP622_16490	COG0577	efflux transmembrane transporter activity
MP622_16495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MP622_16520	COG0028	Belongs to the TPP enzyme family
MP622_16525	COG0440	acetolactate synthase activity
MP622_16565	COG2975	iron-sulfur cluster assembly
MP622_16605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MP622_16630	COG1862	Preprotein translocase
MP622_16640	COG2203	Gaf domain
MP622_16640	COG3706	GGDEF domain
MP622_16640	COG4251	negative regulation of phosphorylation
MP622_16640	COG5001	Diguanylate cyclase
MP622_16645	COG1704	LemA family
MP622_16655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MP622_16700	COG1570	exodeoxyribonuclease VII activity
MP622_16720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MP622_16750	COG4680	protein conserved in bacteria
MP622_16785	COG2184	nucleotidyltransferase activity
MP622_16800	COG0697	spore germination
MP622_16825	COG0069	glutamate synthase activity
MP622_16830	COG2218	PFAM glutamate synthase alpha subunit domain protein
MP622_16835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MP622_16850	COG0004	ammonium transporteR
MP622_16865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MP622_16885	COG2197	response regulator
MP622_16890	COG3850	Histidine kinase
MP622_16895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MP622_16900	COG0004	ammonium transporteR
MP622_16905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MP622_16910	COG1012	belongs to the aldehyde dehydrogenase family
MP622_16920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MP622_16925	COG1012	belongs to the aldehyde dehydrogenase family
MP622_16930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MP622_16935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MP622_16940	COG2267	carboxylic ester hydrolase activity
MP622_16965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MP622_16965	COG0446	pyridine nucleotide-disulphide oxidoreductase
MP622_16980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MP622_17015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MP622_17030	COG0640	Transcriptional regulator
MP622_17045	COG0589	response to stress
MP622_17055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MP622_17060	COG0573	inorganic phosphate transmembrane transporter activity
MP622_17065	COG0581	inorganic phosphate transmembrane transporter activity
MP622_17070	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MP622_17080	COG0745	RESPONSE REGULATOR receiver
MP622_17090	COG0640	Transcriptional regulator
MP622_17100	COG0798	PFAM Bile acid sodium symporter
MP622_17105	COG0431	NADPH-dependent FMN reductase
MP622_17110	COG0492	ferredoxin-NADP+ reductase activity
MP622_17115	COG2072	flavoprotein involved in K transport
MP622_17235	COG2217	Heavy metal translocating P-type atpase
MP622_17240	COG3174	membrane
MP622_17245	COG2205	protein histidine kinase activity
MP622_17260	COG2132	Multicopper oxidase
MP622_17285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MP622_17300	COG2207	Transcriptional regulator
MP622_17305	COG2801	Transposase and inactivated derivatives
MP622_17320	COG3621	Patatin-like phospholipase
MP622_17345	COG3550	peptidyl-serine autophosphorylation
MP622_17365	COG0582	viral genome integration into host DNA
MP622_17370	COG0464	growth