locus-tag	class	description
LXF01_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXF01_00010	COG0592	DNA-directed DNA polymerase activity
LXF01_00020	COG0187	DNA topoisomerase II activity
LXF01_00030	COG0488	(ABC) transporter
LXF01_00085	COG0657	acetylesterase activity
LXF01_00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LXF01_00125	COG2814	Major facilitator Superfamily
LXF01_00130	COG1012	belongs to the aldehyde dehydrogenase family
LXF01_00135	COG3738	Protein conserved in bacteria
LXF01_00140	COG0733	neurotransmitter:sodium symporter activity
LXF01_00150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LXF01_00150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXF01_00160	COG0129	dihydroxy-acid dehydratase activity
LXF01_00165	COG0129	dihydroxy-acid dehydratase activity
LXF01_00195	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LXF01_00215	COG0583	DNA-binding transcription factor activity
LXF01_00220	COG2233	PERMEase
LXF01_00230	COG1309	transcriptional regulator
LXF01_00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXF01_00255	COG3307	-O-antigen
LXF01_00280	COG1064	alcohol dehydrogenase
LXF01_00285	COG2818	Glycosylase
LXF01_00300	COG1194	a g-specific adenine glycosylase
LXF01_00340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LXF01_00370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXF01_00380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXF01_00390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LXF01_00395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXF01_00400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LXF01_00405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LXF01_00410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXF01_00415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LXF01_00425	COG1309	transcriptional regulator
LXF01_00460	COG1454	alcohol dehydrogenase
LXF01_00465	COG0281	malic enzyme
LXF01_00470	COG2011	ABC-type metal ion transport system permease component
LXF01_00475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXF01_00515	COG0271	Belongs to the BolA IbaG family
LXF01_00525	COG1192	Involved in chromosome partitioning
LXF01_00540	COG0586	Pfam SNARE associated Golgi protein
LXF01_00545	COG2259	Doxx family
LXF01_00550	COG0519	Catalyzes the synthesis of GMP from XMP
LXF01_00550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXF01_00555	COG1715	Restriction endonuclease
LXF01_00560	COG3706	GGDEF domain
LXF01_00620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXF01_00640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXF01_00645	COG3829	transcription factor binding
LXF01_00660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXF01_00665	COG0534	Mate efflux family protein
LXF01_00670	COG0436	Aminotransferase
LXF01_00690	COG2837	iron assimilation
LXF01_00695	COG1280	lysine exporter protein (LysE YggA)
LXF01_00700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXF01_00705	COG1121	(ABC) transporter
LXF01_00795	COG0386	Belongs to the glutathione peroxidase family
LXF01_00815	COG0758	DNA mediated transformation
LXF01_00850	COG1131	(ABC) transporter
LXF01_00885	COG2814	Major facilitator Superfamily
LXF01_00910	COG0477	Major facilitator Superfamily
LXF01_00915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXF01_00930	COG2814	Major facilitator Superfamily
LXF01_00950	COG1253	flavin adenine dinucleotide binding
LXF01_00960	COG2860	membrane
LXF01_00965	COG0477	Major facilitator Superfamily
LXF01_00975	COG0318	PFAM AMP-dependent synthetase and ligase
LXF01_00990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LXF01_01020	COG0347	Belongs to the P(II) protein family
LXF01_01025	COG0004	ammonium transporteR
LXF01_01035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXF01_01035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXF01_01050	COG0586	Pfam SNARE associated Golgi protein
LXF01_01075	COG0795	lipopolysaccharide-transporting ATPase activity
LXF01_01080	COG0795	lipopolysaccharide-transporting ATPase activity
LXF01_01085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LXF01_01090	COG0793	Belongs to the peptidase S41A family
LXF01_01105	COG2197	response regulator
LXF01_01115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LXF01_01130	COG4974	Belongs to the 'phage' integrase family
LXF01_01155	COG0772	Belongs to the SEDS family
LXF01_01165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXF01_01170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXF01_01185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LXF01_01195	COG1538	Outer membrane efflux protein
LXF01_01205	COG1132	(ABC) transporter
LXF01_01220	COG1289	transmembrane transporter activity
LXF01_01235	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LXF01_01250	COG0497	DNA recombination
LXF01_01255	COG3123	guanosine phosphorylase activity
LXF01_01260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXF01_01270	COG0237	dephospho-CoA kinase activity
LXF01_01325	COG0779	Required for maturation of 30S ribosomal subunits
LXF01_01330	COG0195	Participates in both transcription termination and antitermination
LXF01_01340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LXF01_01350	COG1320	monovalent cation:proton antiporter activity
LXF01_01355	COG2212	antiporter activity
LXF01_01360	COG1863	multisubunit Na H antiporter MnhE subunit
LXF01_01365	COG0651	ATP synthesis coupled electron transport
LXF01_01370	COG1006	Multisubunit Na H antiporter MnhC subunit
LXF01_01375	COG2111	Na H antiporter
LXF01_01375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXF01_01390	COG0140	phosphoribosyl-ATP diphosphatase activity
LXF01_01390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXF01_01400	COG4221	oxidoreductase activity
LXF01_01410	COG0488	(ABC) transporter
LXF01_01450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXF01_01470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LXF01_01475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LXF01_01485	COG2226	methyltransferase
LXF01_01535	COG0067	glutamate synthase
LXF01_01535	COG0069	glutamate synthase activity
LXF01_01535	COG0070	glutamate synthase
LXF01_01540	COG0493	'glutamate synthase
LXF01_01550	COG1704	LemA family
LXF01_01595	COG3620	sequence-specific DNA binding
LXF01_01690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXF01_01695	COG1758	RNA polymerase activity
LXF01_01700	COG0194	GDP metabolic process
LXF01_01710	COG4968	Prepilin-type N-terminal cleavage methylation domain
LXF01_01745	COG0228	four-way junction DNA binding
LXF01_01750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LXF01_01760	COG0335	large ribosomal subunit rRNA binding
LXF01_01770	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LXF01_01775	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LXF01_01780	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LXF01_01785	COG5380	lipid catabolic process
LXF01_01790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LXF01_01810	COG5006	permease, DMT superfamily
LXF01_01815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXF01_01820	COG0277	FAD linked oxidase domain protein
LXF01_01845	COG2814	Major facilitator Superfamily
LXF01_01865	COG2032	superoxide dismutase activity
LXF01_01870	COG0628	permease
LXF01_01875	COG1192	Involved in chromosome partitioning
LXF01_01890	COG2226	methyltransferase
LXF01_01910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXF01_01915	COG0254	rRNA binding
LXF01_01920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LXF01_01935	COG0534	Mate efflux family protein
LXF01_01945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXF01_01960	COG1960	acyl-CoA dehydrogenase activity
LXF01_01980	COG0408	coproporphyrinogen oxidase activity
LXF01_01985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXF01_02005	COG0513	Belongs to the DEAD box helicase family
LXF01_02010	COG1127	ABC transporter
LXF01_02015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LXF01_02020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LXF01_02025	COG2854	intermembrane phospholipid transfer
LXF01_02035	COG0598	Magnesium transport protein CorA
LXF01_02050	COG1040	competence protein
LXF01_02055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LXF01_02070	COG2937	Belongs to the GPAT DAPAT family
LXF01_02075	COG1946	Acyl-CoA thioesterase
LXF01_02080	COG1301	dicarboxylic acid transport
LXF01_02100	COG1959	2 iron, 2 sulfur cluster binding
LXF01_02110	COG0433	COG0433 Predicted ATPase
LXF01_02115	COG0626	cystathionine gamma-synthase activity
LXF01_02130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LXF01_02135	COG0088	Forms part of the polypeptide exit tunnel
LXF01_02150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LXF01_02200	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LXF01_02205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LXF01_02215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LXF01_02240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LXF01_02255	COG0202	RNA polymerase activity
LXF01_02260	COG0203	ribosomal protein L17
LXF01_02265	COG2072	flavoprotein involved in K transport
LXF01_02275	COG1960	acyl-CoA dehydrogenase activity
LXF01_02280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LXF01_02305	COG0697	spore germination
LXF01_02315	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LXF01_02320	COG0339	signal peptide processing
LXF01_02330	COG0557	exoribonuclease II activity
LXF01_02365	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXF01_02385	COG1295	ribonuclease BN
LXF01_02430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LXF01_02435	COG1702	phosphate starvation-inducible protein PhoH
LXF01_02440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXF01_02445	COG0739	heme binding
LXF01_02445	COG1196	nuclear chromosome segregation
LXF01_02445	COG0741	lytic transglycosylase activity
LXF01_02480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LXF01_02485	COG1183	phosphatidylcholine synthase activity
LXF01_02550	COG1607	acyl-coa hydrolase
LXF01_02585	COG2350	Protein conserved in bacteria
LXF01_02595	COG0613	PHP domain protein
LXF01_02605	COG3781	membrane
LXF01_02610	COG2003	Belongs to the UPF0758 family
LXF01_02615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXF01_02620	COG0495	leucyl-tRNA aminoacylation
LXF01_02625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXF01_02645	COG2814	Major facilitator Superfamily
LXF01_02650	COG0697	spore germination
LXF01_02670	COG0004	ammonium transporteR
LXF01_02685	COG3622	Belongs to the hyi family
LXF01_02690	COG2084	Dehydrogenase
LXF01_02695	COG1024	Enoyl-CoA hydratase
LXF01_02700	COG2205	protein histidine kinase activity
LXF01_02700	COG5002	protein histidine kinase activity
LXF01_02700	COG0784	Response regulator, receiver
LXF01_02720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXF01_02735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXF01_02740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXF01_02750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXF01_02765	COG2986	histidine ammonia-lyase
LXF01_02805	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_02810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXF01_02835	COG1862	Preprotein translocase
LXF01_02850	COG1704	LemA family
LXF01_02860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LXF01_02885	COG5002	protein histidine kinase activity
LXF01_02890	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LXF01_02905	COG2194	sulfuric ester hydrolase activity
LXF01_02910	COG0726	polysaccharide deacetylase
LXF01_02915	COG0438	transferase activity, transferring glycosyl groups
LXF01_02950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LXF01_02995	COG1960	acyl-CoA dehydrogenase activity
LXF01_03000	COG1960	acyl-CoA dehydrogenase activity
LXF01_03010	COG2205	protein histidine kinase activity
LXF01_03015	COG0745	RESPONSE REGULATOR receiver
LXF01_03035	COG1113	amino acid transport
LXF01_03045	COG2315	Protein conserved in bacteria
LXF01_03055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LXF01_03075	COG2096	Adenosyltransferase
LXF01_03080	COG4206	TonB-dependent receptor
LXF01_03085	COG4206	TonB-dependent receptor
LXF01_03140	COG0285	dihydrofolate synthase activity
LXF01_03160	COG0450	alkyl hydroperoxide reductase
LXF01_03175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXF01_03180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LXF01_03225	COG2885	chlorophyll binding
LXF01_03230	COG5001	Diguanylate cyclase
LXF01_03230	COG3300	MHYT domain
LXF01_03285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LXF01_03290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXF01_03350	COG1214	PFAM Peptidase M22, glycoprotease
LXF01_03355	COG1968	undecaprenyl-diphosphatase activity
LXF01_03375	COG4269	membrane
LXF01_03390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LXF01_03400	COG2132	Multicopper oxidase
LXF01_03410	COG2076	Multidrug Resistance protein
LXF01_03440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXF01_03445	COG1278	Cold shock
LXF01_03455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXF01_03460	COG3545	Serine hydrolase
LXF01_03475	COG0730	response to heat
LXF01_03485	COG1196	nuclear chromosome segregation
LXF01_03495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LXF01_03500	COG0833	amino acid
LXF01_03510	COG2233	PERMEase
LXF01_03515	COG1217	gtp-binding protein TYPA
LXF01_03530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXF01_03540	COG3659	wide pore channel activity
LXF01_03545	COG4772	TonB-dependent receptor
LXF01_03550	COG1902	pentaerythritol trinitrate reductase activity
LXF01_03575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXF01_03585	COG0354	folic acid binding
LXF01_03590	COG2132	Multicopper oxidase
LXF01_03590	COG2132	Multicopper oxidase
LXF01_03605	COG4456	Virulence-associated protein
LXF01_03610	COG1487	ribonuclease activity
LXF01_03645	COG0564	pseudouridine synthase activity
LXF01_03665	COG3189	MarR family transcriptional regulator
LXF01_03670	COG2824	Alkylphosphonate utilization operon protein PhnA
LXF01_03700	COG0628	permease
LXF01_03705	COG5342	invasion associated locus B
LXF01_03710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXF01_03710	COG0352	thiamine-phosphate diphosphorylase activity
LXF01_03710	COG0351	phosphomethylpyrimidine kinase
LXF01_03740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXF01_03745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LXF01_03745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXF01_03750	COG0745	RESPONSE REGULATOR receiver
LXF01_03755	COG2205	protein histidine kinase activity
LXF01_03765	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXF01_03775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXF01_03775	COG0649	NAD binding
LXF01_03785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LXF01_03800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXF01_03810	COG0713	ATP synthesis coupled electron transport
LXF01_03815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXF01_03820	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXF01_03830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LXF01_03840	COG1278	Cold shock
LXF01_03845	COG0583	DNA-binding transcription factor activity
LXF01_03855	COG1126	abc transporter atp-binding protein
LXF01_03860	COG0765	amino acid transport
LXF01_03865	COG0765	amino acid transport
LXF01_03885	COG0668	transmembrane transport
LXF01_03900	COG2081	HI0933 family
LXF01_03965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXF01_03965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXF01_03985	COG0489	protein tyrosine kinase activity
LXF01_04000	COG2358	TRAP transporter, solute receptor (TAXI family
LXF01_04035	COG0442	prolyl-tRNA aminoacylation
LXF01_04070	COG0840	transmembrane signaling receptor activity
LXF01_04075	COG0643	Histidine kinase
LXF01_04075	COG2198	Histidine kinase
LXF01_04100	COG2832	Protein of unknown function (DUF454)
LXF01_04160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXF01_04170	COG1289	transmembrane transporter activity
LXF01_04175	COG2814	Major facilitator Superfamily
LXF01_04185	COG0786	glutamate:sodium symporter activity
LXF01_04190	COG1115	amino acid carrier protein
LXF01_04195	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXF01_04205	COG1607	acyl-coa hydrolase
LXF01_04215	COG2814	Major facilitator Superfamily
LXF01_04220	COG0583	DNA-binding transcription factor activity
LXF01_04250	COG0523	cobalamin synthesis protein
LXF01_04255	COG4681	YaeQ
LXF01_04265	COG2199	diguanylate cyclase activity
LXF01_04265	COG2203	Gaf domain
LXF01_04290	COG1024	Enoyl-CoA hydratase
LXF01_04315	COG0477	Major facilitator Superfamily
LXF01_04320	COG0242	peptide deformylase activity
LXF01_04335	COG2066	Belongs to the glutaminase family
LXF01_04345	COG2852	Protein conserved in bacteria
LXF01_04355	COG0525	valine-tRNA ligase activity
LXF01_04365	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_04380	COG0393	Putative heavy-metal-binding
LXF01_04385	COG1538	Outer membrane efflux protein
LXF01_04395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXF01_04400	COG0671	phosphoesterase, PA-phosphatase related
LXF01_04415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LXF01_04420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LXF01_04440	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LXF01_04450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LXF01_04455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXF01_04455	COG1648	precorrin-2 dehydrogenase activity
LXF01_04460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LXF01_04495	COG0531	amino acid
LXF01_04510	COG0321	lipoyl(octanoyl) transferase activity
LXF01_04520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXF01_04545	COG0586	Pfam SNARE associated Golgi protein
LXF01_04570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXF01_04595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LXF01_04600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXF01_04630	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LXF01_04645	COG0358	DNA primase activity
LXF01_04655	COG0564	pseudouridine synthase activity
LXF01_04685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXF01_04710	COG0110	maltose O-acetyltransferase activity
LXF01_04715	COG0251	oxidation-reduction process
LXF01_04720	COG1309	transcriptional regulator
LXF01_04730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXF01_04735	COG0505	Belongs to the CarA family
LXF01_04760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXF01_04765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXF01_04795	COG2851	Citrate transporter
LXF01_04805	COG1253	flavin adenine dinucleotide binding
LXF01_04835	COG0584	glycerophosphoryl diester phosphodiesterase
LXF01_04845	COG2239	Acts as a magnesium transporter
LXF01_04860	COG0741	lytic transglycosylase activity
LXF01_04860	COG1196	nuclear chromosome segregation
LXF01_04860	COG0739	heme binding
LXF01_04865	COG0037	tRNA processing
LXF01_04880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXF01_04895	COG0235	Class ii aldolase
LXF01_04905	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LXF01_04920	COG0280	phosphate acetyltransferase
LXF01_04920	COG0281	malic enzyme
LXF01_04930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXF01_04935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXF01_04940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LXF01_04965	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LXF01_05000	COG1115	amino acid carrier protein
LXF01_05005	COG1113	amino acid transport
LXF01_05015	COG0019	diaminopimelate decarboxylase activity
LXF01_05030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LXF01_05040	COG1522	sequence-specific DNA binding
LXF01_05045	COG1280	lysine exporter protein (LysE YggA)
LXF01_05075	COG1301	dicarboxylic acid transport
LXF01_05095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXF01_05115	COG1671	Belongs to the UPF0178 family
LXF01_05120	COG0697	spore germination
LXF01_05135	COG1136	(ABC) transporter
LXF01_05140	COG0658	competence protein
LXF01_05140	COG2333	competence protein COMEC
LXF01_05165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LXF01_05170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LXF01_05175	COG0628	permease
LXF01_05210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXF01_05230	COG0823	Involved in the tonB-independent uptake of proteins
LXF01_05250	COG0824	Thioesterase
LXF01_05260	COG2255	four-way junction helicase activity
LXF01_05280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXF01_05280	COG0047	phosphoribosylformylglycinamidine synthase activity
LXF01_05295	COG0583	DNA-binding transcription factor activity
LXF01_05300	COG3323	Protein of unknown function (DUF1653)
LXF01_05300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXF01_05305	COG0778	Nitroreductase
LXF01_05310	COG1024	Enoyl-CoA hydratase
LXF01_05315	COG1051	belongs to the nudix hydrolase family
LXF01_05315	COG1056	cytidyltransferase-related domain
LXF01_05320	COG2353	YceI-like domain
LXF01_05325	COG0583	DNA-binding transcription factor activity
LXF01_05335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXF01_05345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LXF01_05350	COG0602	queuosine metabolic process
LXF01_05370	COG0583	DNA-binding transcription factor activity
LXF01_05375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LXF01_05380	COG4208	sulfate ABC transporter
LXF01_05395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXF01_05400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXF01_05405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXF01_05410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXF01_05415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LXF01_05440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXF01_05455	COG0681	Belongs to the peptidase S26 family
LXF01_05465	COG0571	ribonuclease III activity
LXF01_05470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXF01_05480	COG1381	Involved in DNA repair and RecF pathway recombination
LXF01_05485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LXF01_05525	COG0436	Aminotransferase
LXF01_05535	COG0052	Belongs to the universal ribosomal protein uS2 family
LXF01_05560	COG2951	lytic endotransglycosylase activity
LXF01_05575	COG0842	Transport permease protein
LXF01_05580	COG1131	(ABC) transporter
LXF01_05615	COG1741	Belongs to the pirin family
LXF01_05630	COG3739	integral membrane protein
LXF01_05645	COG3706	GGDEF domain
LXF01_05665	COG0302	gtp cyclohydrolase
LXF01_05685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXF01_05690	COG0512	Glutamine amidotransferase of anthranilate synthase
LXF01_05695	COG0174	glutamine synthetase
LXF01_05710	COG3161	chorismate lyase activity
LXF01_05715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LXF01_05760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXF01_05765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXF01_05770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXF01_05785	COG1960	acyl-CoA dehydrogenase activity
LXF01_05790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LXF01_05800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXF01_05825	COG2175	clavaminate synthase activity
LXF01_05845	COG2199	diguanylate cyclase activity
LXF01_05860	COG0556	nucleotide-excision repair
LXF01_05895	COG0702	epimerase
LXF01_05900	COG1733	regulation of RNA biosynthetic process
LXF01_05925	COG0431	NADPH-dependent FMN reductase
LXF01_05930	COG0798	PFAM Bile acid sodium symporter
LXF01_05940	COG0640	Transcriptional regulator
LXF01_05945	COG4772	TonB-dependent receptor
LXF01_05955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXF01_05960	COG0076	glutamate decarboxylase activity
LXF01_05970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LXF01_05975	COG0573	inorganic phosphate transmembrane transporter activity
LXF01_05985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXF01_05990	COG0616	signal peptide processing
LXF01_06020	COG0482	sulfurtransferase activity
LXF01_06040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXF01_06045	COG1686	Belongs to the peptidase S11 family
LXF01_06070	COG0583	DNA-binding transcription factor activity
LXF01_06075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXF01_06080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LXF01_06085	COG1067	ATP-dependent peptidase activity
LXF01_06135	COG1966	Carbon starvation protein
LXF01_06140	COG2879	small protein
LXF01_06145	COG0714	Associated with various cellular activities
LXF01_06170	COG1765	OsmC-like protein
LXF01_06180	COG0667	Aldo Keto reductase
LXF01_06185	COG0542	response to heat
LXF01_06225	COG0540	Belongs to the ATCase OTCase family
LXF01_06245	COG0589	response to stress
LXF01_06250	COG0589	response to stress
LXF01_06260	COG2076	Multidrug Resistance protein
LXF01_06265	COG1309	transcriptional regulator
LXF01_06270	COG3135	benzoate transporter
LXF01_06280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXF01_06285	COG0583	DNA-binding transcription factor activity
LXF01_06300	COG0183	Belongs to the thiolase family
LXF01_06305	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_06315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXF01_06330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LXF01_06335	COG0824	Thioesterase
LXF01_06340	COG1454	alcohol dehydrogenase
LXF01_06345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXF01_06365	COG0069	glutamate synthase activity
LXF01_06385	COG1305	Transglutaminase-like
LXF01_06395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXF01_06400	COG0305	Participates in initiation and elongation during chromosome replication
LXF01_06415	COG0360	Binds together with S18 to 16S ribosomal RNA
LXF01_06425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LXF01_06430	COG1845	cytochrome c oxidase, subunit III
LXF01_06435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXF01_06440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXF01_06465	COG4682	membrane
LXF01_06470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXF01_06490	COG2890	protein-(glutamine-N5) methyltransferase activity
LXF01_06495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXF01_06500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXF01_06510	COG2207	Transcriptional regulator
LXF01_06520	COG1960	acyl-CoA dehydrogenase activity
LXF01_06525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXF01_06535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LXF01_06545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LXF01_06555	COG0586	Pfam SNARE associated Golgi protein
LXF01_06575	COG0729	surface antigen
LXF01_06635	COG5377	YqaJ viral recombinase family
LXF01_06760	COG5410	chromosome segregation
LXF01_06965	COG5377	YqaJ viral recombinase family
LXF01_07090	COG5410	chromosome segregation
LXF01_07250	COG1570	exodeoxyribonuclease VII activity
LXF01_07255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXF01_07300	COG0210	DNA helicase
LXF01_07310	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LXF01_07345	COG4584	PFAM Integrase catalytic
LXF01_07350	COG1484	DNA-dependent DNA replication
LXF01_07410	COG1114	Component of the transport system for branched-chain amino acids
LXF01_07415	COG0024	Methionine aminopeptidase
LXF01_07425	COG0583	DNA-binding transcription factor activity
LXF01_07430	COG0583	DNA-binding transcription factor activity
LXF01_07435	COG2267	carboxylic ester hydrolase activity
LXF01_07445	COG1902	pentaerythritol trinitrate reductase activity
LXF01_07445	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXF01_07460	COG2814	Major facilitator Superfamily
LXF01_07470	COG0583	DNA-binding transcription factor activity
LXF01_07490	COG0148	phosphopyruvate hydratase activity
LXF01_07505	COG0772	Belongs to the SEDS family
LXF01_07520	COG4890	Cyd operon protein YbgT
LXF01_07525	COG1294	oxidase, subunit
LXF01_07575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LXF01_07595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXF01_07610	COG0133	tryptophan synthase activity
LXF01_07620	COG0517	IMP dehydrogenase activity
LXF01_07620	COG0516	GMP reductase activity
LXF01_07655	COG0552	protein localization to endoplasmic reticulum
LXF01_07735	COG1960	acyl-CoA dehydrogenase activity
LXF01_07800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LXF01_07805	COG0730	response to heat
LXF01_07810	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LXF01_07820	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXF01_07825	COG2207	Transcriptional regulator
LXF01_07830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXF01_07835	COG4589	Belongs to the CDS family
LXF01_07850	COG2453	phosphatase
LXF01_07850	COG0671	phosphoesterase, PA-phosphatase related
LXF01_07855	COG2267	carboxylic ester hydrolase activity
LXF01_07860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXF01_07865	COG1946	Acyl-CoA thioesterase
LXF01_07925	COG2223	nitrite transmembrane transporter activity
LXF01_07940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXF01_07955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LXF01_07980	COG0583	DNA-binding transcription factor activity
LXF01_08005	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LXF01_08010	COG0671	phosphoesterase, PA-phosphatase related
LXF01_08015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXF01_08035	COG1960	acyl-CoA dehydrogenase activity
LXF01_08040	COG2207	Transcriptional regulator
LXF01_08045	COG2814	Major facilitator Superfamily
LXF01_08055	COG3152	Membrane
LXF01_08070	COG1960	acyl-CoA dehydrogenase activity
LXF01_08115	COG0697	spore germination
LXF01_08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXF01_08160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LXF01_08170	COG0509	glycine decarboxylation via glycine cleavage system
LXF01_08185	COG1132	(ABC) transporter
LXF01_08190	COG3706	GGDEF domain
LXF01_08195	COG0668	transmembrane transport
LXF01_08200	COG3122	Protein conserved in bacteria
LXF01_08225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXF01_08235	COG0789	Transcriptional regulator
LXF01_08250	COG1960	acyl-CoA dehydrogenase activity
LXF01_08255	COG0183	Belongs to the thiolase family
LXF01_08260	COG0427	acetyl-CoA hydrolase
LXF01_08270	COG0546	phosphoglycolate phosphatase activity
LXF01_08280	COG4521	taurine ABC transporter
LXF01_08285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LXF01_08290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXF01_08295	COG2175	clavaminate synthase activity
LXF01_08310	COG0439	Biotin carboxylase
LXF01_08345	COG0864	Transcriptional regulator
LXF01_08355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXF01_08370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LXF01_08375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXF01_08380	COG0730	response to heat
LXF01_08410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LXF01_08420	COG1960	acyl-CoA dehydrogenase activity
LXF01_08425	COG2814	Major facilitator Superfamily
LXF01_08435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXF01_08440	COG0183	Belongs to the thiolase family
LXF01_08445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXF01_08450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXF01_08455	COG4829	muconolactone delta-isomerase
LXF01_08460	COG4948	Mandelate Racemase Muconate Lactonizing
LXF01_08470	COG1116	anion transmembrane transporter activity
LXF01_08470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXF01_08480	COG2223	nitrite transmembrane transporter activity
LXF01_08485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXF01_08490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXF01_08495	COG0243	molybdopterin cofactor binding
LXF01_08505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LXF01_08515	COG0314	molybdopterin synthase activity
LXF01_08520	COG0315	cyclic pyranopterin monophosphate synthase activity
LXF01_08520	COG0521	Mo-molybdopterin cofactor biosynthetic process
LXF01_08525	COG0303	'Molybdopterin
LXF01_08530	COG0725	ABC transporter, periplasmic molybdate-binding protein
LXF01_08535	COG4149	molybdate abc transporter
LXF01_08565	COG4628	conserved protein (DUF2132)
LXF01_08570	COG0477	Major facilitator Superfamily
LXF01_08575	COG2030	dehydratase
LXF01_08575	COG1012	belongs to the aldehyde dehydrogenase family
LXF01_08580	COG3396	Phenylacetate-CoA oxygenase
LXF01_08585	COG3460	Phenylacetate-CoA oxygenase
LXF01_08590	COG3396	Phenylacetate-CoA oxygenase
LXF01_08595	COG2151	metal-sulfur cluster biosynthetic enzyme
LXF01_08600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXF01_08605	COG1024	Enoyl-CoA hydratase
LXF01_08610	COG1024	Enoyl-CoA hydratase
LXF01_08615	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXF01_08620	COG0183	Belongs to the thiolase family
LXF01_08625	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LXF01_08630	COG3327	negative regulation of DNA-templated transcription, initiation
LXF01_08740	COG0477	Major facilitator Superfamily
LXF01_08745	COG1024	Enoyl-CoA hydratase
LXF01_08750	COG1024	Enoyl-CoA hydratase
LXF01_08755	COG1960	acyl-CoA dehydrogenase activity
LXF01_08760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXF01_08775	COG0583	DNA-binding transcription factor activity
LXF01_08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXF01_08810	COG2814	Major facilitator Superfamily
LXF01_08815	COG0583	DNA-binding transcription factor activity
LXF01_08825	COG4638	Rieske (2fe-2S)
LXF01_08830	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LXF01_08835	COG0633	Ferredoxin
LXF01_08835	COG0543	2 iron, 2 sulfur cluster binding
LXF01_08840	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_08845	COG3135	benzoate transporter
LXF01_08865	COG0583	DNA-binding transcription factor activity
LXF01_08870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXF01_08875	COG4266	Belongs to the allantoicase family
LXF01_08885	COG2233	PERMEase
LXF01_08890	COG2351	hydroxyisourate hydrolase activity
LXF01_08920	COG0697	spore germination
LXF01_08935	COG0318	PFAM AMP-dependent synthetase and ligase
LXF01_09025	COG0596	Alpha beta hydrolase
LXF01_09070	COG0439	Biotin carboxylase
LXF01_09080	COG3706	GGDEF domain
LXF01_09085	COG2814	Major facilitator Superfamily
LXF01_09115	COG2323	membrane
LXF01_09125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXF01_09175	COG1278	Cold shock
LXF01_09205	COG0372	Belongs to the citrate synthase family
LXF01_09235	COG0542	response to heat
LXF01_09240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LXF01_09265	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LXF01_09270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXF01_09280	COG0569	domain protein
LXF01_09285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXF01_09310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXF01_09320	COG1585	Membrane protein implicated in regulation of membrane protease activity
LXF01_09355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXF01_09385	COG0822	iron-sulfur transferase activity
LXF01_09390	COG0316	Belongs to the HesB IscA family
LXF01_09420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LXF01_09430	COG1027	Aspartate ammonia-lyase
LXF01_09435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXF01_09450	COG0506	proline dehydrogenase activity
LXF01_09450	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LXF01_09450	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LXF01_09470	COG3698	Phosphodiester glycosidase
LXF01_09485	COG0667	Aldo Keto reductase
LXF01_09490	COG0583	DNA-binding transcription factor activity
LXF01_09495	COG3781	membrane
LXF01_09550	COG0697	spore germination
LXF01_09565	COG0126	phosphoglycerate kinase activity
LXF01_09575	COG0424	maF-like protein
LXF01_09585	COG2850	peptidyl-arginine hydroxylation
LXF01_09595	COG4585	Histidine kinase
LXF01_09600	COG2197	response regulator
LXF01_09610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LXF01_09615	COG0702	epimerase
LXF01_09645	COG1011	Hydrolase
LXF01_09650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LXF01_09660	COG2137	regulation of response to DNA damage stimulus
LXF01_09675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXF01_09685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXF01_09710	COG0575	Belongs to the CDS family
LXF01_09715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXF01_09735	COG3852	Histidine kinase
LXF01_09750	COG2814	Major facilitator Superfamily
LXF01_09785	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LXF01_09790	COG0138	bifunctional purine biosynthesis protein purh
LXF01_09815	COG1464	Belongs to the NlpA lipoprotein family
LXF01_09820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXF01_09825	COG2011	ABC-type metal ion transport system permease component
LXF01_09870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LXF01_09880	COG4122	O-methyltransferase activity
LXF01_09905	COG2274	protein secretion by the type I secretion system
LXF01_09915	COG1137	ATPase activity
LXF01_09920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LXF01_09930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LXF01_09935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LXF01_09935	COG0517	IMP dehydrogenase activity
LXF01_09960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXF01_09960	COG0519	Catalyzes the synthesis of GMP from XMP
LXF01_09965	COG1280	lysine exporter protein (LysE YggA)
LXF01_09990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LXF01_10005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LXF01_10025	COG2391	methyltransferase activity
LXF01_10150	COG0352	thiamine-phosphate diphosphorylase activity
LXF01_10170	COG1309	transcriptional regulator
LXF01_10195	COG0612	Peptidase, M16
LXF01_10205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXF01_10210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXF01_10260	COG0154	amidase activity
LXF01_10265	COG0477	Major facilitator Superfamily
LXF01_10270	COG1522	sequence-specific DNA binding
LXF01_10285	COG1610	YqeY-like protein
LXF01_10330	COG0167	dihydroorotate dehydrogenase activity
LXF01_10355	COG0778	Nitroreductase
LXF01_10365	COG0513	Belongs to the DEAD box helicase family
LXF01_10370	COG1278	Cold shock
LXF01_10385	COG2363	Small membrane protein
LXF01_10405	COG0625	glutathione transferase activity
LXF01_10410	COG0659	secondary active sulfate transmembrane transporter activity
LXF01_10415	COG4585	Histidine kinase
LXF01_10420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXF01_10445	COG0308	aminopeptidase N
LXF01_10480	COG1253	flavin adenine dinucleotide binding
LXF01_10510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LXF01_10515	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LXF01_10530	COG2431	L-lysine efflux transmembrane transporter activity
LXF01_10545	COG0776	regulation of translation
LXF01_10575	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LXF01_10610	COG0084	hydrolase, TatD family'
LXF01_10630	COG1663	tetraacyldisaccharide 4'-kinase activity
LXF01_10635	COG1132	(ABC) transporter
LXF01_10645	COG0811	peptide transport
LXF01_10650	COG1475	DNA binding
LXF01_10655	COG1192	Involved in chromosome partitioning
LXF01_10665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LXF01_10670	COG3178	'Phosphotransferase
LXF01_10680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXF01_10685	COG1923	regulation of RNA biosynthetic process
LXF01_10695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LXF01_10700	COG0802	atpase or kinase
LXF01_10725	COG2707	UPF0756 membrane protein
LXF01_10745	COG0583	DNA-binding transcription factor activity
LXF01_10750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXF01_10770	COG1643	Atp-dependent helicase
LXF01_10800	COG3634	alkyl hydroperoxide reductase activity
LXF01_10815	COG1280	lysine exporter protein (LysE YggA)
LXF01_10830	COG1254	Belongs to the acylphosphatase family
LXF01_10835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LXF01_10835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LXF01_10840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LXF01_10855	COG1944	ATP diphosphatase activity
LXF01_10890	COG0012	GTP binding
LXF01_10905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXF01_10920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LXF01_10950	COG0386	Belongs to the glutathione peroxidase family
LXF01_10955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXF01_10960	COG0436	Aminotransferase
LXF01_10980	COG1187	pseudouridine synthase activity
LXF01_10995	COG1686	Belongs to the peptidase S11 family
LXF01_11000	COG1252	NADH dehydrogenase
LXF01_11020	COG0501	Belongs to the peptidase M48B family
LXF01_11025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LXF01_11040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LXF01_11055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXF01_11060	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LXF01_11065	COG0527	aspartate kinase activity
LXF01_11075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXF01_11085	COG3038	cytochrome b561
LXF01_11095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LXF01_11100	COG2252	PERMEase
LXF01_11125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LXF01_11140	COG0693	protein deglycase activity
LXF01_11145	COG1960	acyl-CoA dehydrogenase activity
LXF01_11150	COG1301	dicarboxylic acid transport
LXF01_11155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXF01_11160	COG3139	Protein of unknown function (DUF1315)
LXF01_11165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXF01_11170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXF01_11180	COG0494	nUDIX hydrolase
LXF01_11190	COG0642	Histidine kinase
LXF01_11205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LXF01_11215	COG1720	tRNA m6t6A37 methyltransferase activity
LXF01_11255	COG0789	Transcriptional regulator
LXF01_11260	COG0826	peptidase U32
LXF01_11265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXF01_11270	COG3634	alkyl hydroperoxide reductase activity
LXF01_11295	COG2862	Uncharacterized protein family, UPF0114
LXF01_11305	COG2175	clavaminate synthase activity
LXF01_11310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXF01_11400	COG1902	pentaerythritol trinitrate reductase activity
LXF01_11400	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXF01_11405	COG0277	FAD linked oxidase domain protein
LXF01_11415	COG2186	Transcriptional regulator
LXF01_11430	COG3706	GGDEF domain
LXF01_11435	COG0418	dihydroorotase activity
LXF01_11440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXF01_11450	COG4771	TonB-dependent receptor
LXF01_11480	COG0833	amino acid
LXF01_11495	COG0833	amino acid
LXF01_11520	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LXF01_11530	COG4172	Belongs to the ABC transporter superfamily
LXF01_11535	COG4239	(ABC) transporter, permease
LXF01_11540	COG4174	ABC transporter (Permease)
LXF01_11545	COG4166	transmembrane transport
LXF01_11550	COG1388	LysM domain
LXF01_11550	COG0741	lytic transglycosylase activity
LXF01_11570	COG0657	acetylesterase activity
LXF01_11605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXF01_11610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXF01_11620	COG0006	proline dipeptidase activity
LXF01_11670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LXF01_11680	COG2234	aminopeptidase activity
LXF01_11690	COG3384	dioxygenase
LXF01_11700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXF01_11705	COG2878	Part of a membrane complex involved in electron transport
LXF01_11710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LXF01_11735	COG0768	penicillin binding
LXF01_11740	COG0742	ribosomal rna small subunit methyltransferase
LXF01_11795	COG1597	lipid kinase activity
LXF01_11800	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LXF01_11815	COG0477	Major facilitator Superfamily
LXF01_11830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LXF01_11845	COG4221	oxidoreductase activity
LXF01_11845	COG3321	synthase
LXF01_11845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXF01_11845	COG0604	alcohol dehydrogenase
LXF01_11865	COG1695	Transcriptional regulator
LXF01_11885	COG0175	sulfate reduction
LXF01_11900	COG2268	Band 7 protein
LXF01_11905	COG0726	polysaccharide deacetylase
LXF01_11905	COG1649	PFAM Uncharacterised BCR, COG1649
LXF01_11915	COG1215	transferase activity, transferring glycosyl groups
LXF01_11920	COG0726	polysaccharide deacetylase
LXF01_11920	COG1649	PFAM Uncharacterised BCR, COG1649
LXF01_11930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXF01_11940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXF01_11955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LXF01_11960	COG1053	succinate dehydrogenase
LXF01_11965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LXF01_11980	COG2072	flavoprotein involved in K transport
LXF01_11995	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LXF01_12010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXF01_12010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LXF01_12060	COG2321	neutral zinc metallopeptidase
LXF01_12065	COG2354	Protein conserved in bacteria
LXF01_12090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXF01_12095	COG1773	rubredoxin
LXF01_12100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXF01_12110	COG0583	DNA-binding transcription factor activity
LXF01_12135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LXF01_12140	COG4181	ATPase activity
LXF01_12190	COG0306	phosphate transporter
LXF01_12215	COG2852	Protein conserved in bacteria
LXF01_12225	COG2376	Dihydroxyacetone kinase
LXF01_12230	COG2323	membrane
LXF01_12235	COG0004	ammonium transporteR
LXF01_12250	COG0642	Histidine kinase
LXF01_12255	COG0745	RESPONSE REGULATOR receiver
LXF01_12260	COG2194	sulfuric ester hydrolase activity
LXF01_12280	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXF01_12295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXF01_12300	COG0142	geranyltranstransferase activity
LXF01_12305	COG3706	GGDEF domain
LXF01_12310	COG2828	Protein conserved in bacteria
LXF01_12315	COG1113	amino acid transport
LXF01_12340	COG0560	Phosphoserine phosphatase
LXF01_12350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXF01_12360	COG1530	ribonuclease E activity
LXF01_12365	COG0424	maF-like protein
LXF01_12370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LXF01_12375	COG1792	Involved in formation and maintenance of cell shape
LXF01_12380	COG1077	Cell shape determining protein MreB Mrl
LXF01_12385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXF01_12395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXF01_12400	COG2801	Transposase and inactivated derivatives
LXF01_12435	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LXF01_12470	COG1053	succinate dehydrogenase
LXF01_12475	COG0583	DNA-binding transcription factor activity
LXF01_12485	COG1294	oxidase, subunit
LXF01_12490	COG1271	oxidase subunit
LXF01_12530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXF01_12540	COG0745	RESPONSE REGULATOR receiver
LXF01_12545	COG0642	Histidine kinase
LXF01_12550	COG3177	Filamentation induced by cAMP protein fic
LXF01_12580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LXF01_12675	COG0582	viral genome integration into host DNA
LXF01_12685	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXF01_12690	COG2814	Major facilitator Superfamily
LXF01_12695	COG1566	PFAM secretion protein HlyD family protein
LXF01_12700	COG2050	protein possibly involved in aromatic compounds catabolism
LXF01_12715	COG1090	epimerase
LXF01_12725	COG2203	Gaf domain
LXF01_12725	COG4251	negative regulation of phosphorylation
LXF01_12725	COG5001	Diguanylate cyclase
LXF01_12725	COG3706	GGDEF domain
LXF01_12730	COG0420	3'-5' exonuclease activity
LXF01_12760	COG0735	belongs to the Fur family
LXF01_12765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXF01_12770	COG2914	Belongs to the UPF0125 (RnfH) family
LXF01_12785	COG0121	glutamine amidotransferase
LXF01_12795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXF01_12800	COG0756	dUTP diphosphatase activity
LXF01_12805	COG0210	DNA helicase
LXF01_12810	COG2885	chlorophyll binding
LXF01_12815	COG0204	Acyl-transferase
LXF01_12835	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LXF01_12850	COG0583	DNA-binding transcription factor activity
LXF01_12855	COG1674	ftsk spoiiie
LXF01_12860	COG0492	ferredoxin-NADP+ reductase activity
LXF01_12865	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LXF01_12870	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LXF01_12875	COG0456	acetyltransferase
LXF01_12890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LXF01_12915	COG1981	membrane
LXF01_12925	COG1652	LysM domain
LXF01_12935	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_12950	COG1399	metal-binding, possibly nucleic acid-binding protein
LXF01_12955	COG3101	peptidyl-lysine hydroxylation
LXF01_12960	COG0009	L-threonylcarbamoyladenylate synthase
LXF01_12975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LXF01_12980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LXF01_12995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXF01_13045	COG0590	tRNA wobble adenosine to inosine editing
LXF01_13055	COG4106	trans-aconitate 2-methyltransferase activity
LXF01_13070	COG2226	methyltransferase
LXF01_13070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXF01_13070	COG0596	Alpha beta hydrolase
LXF01_13075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXF01_13080	COG2193	ferroxidase activity
LXF01_13085	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LXF01_13095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXF01_13115	COG0183	Belongs to the thiolase family
LXF01_13130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXF01_13145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LXF01_13150	COG2207	Transcriptional regulator
LXF01_13160	COG0183	Belongs to the thiolase family
LXF01_13165	COG1024	Enoyl-CoA hydratase
LXF01_13165	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXF01_13185	COG1272	protein, Hemolysin III
LXF01_13190	COG0477	Major facilitator Superfamily
LXF01_13195	COG1408	metallophosphoesterase
LXF01_13200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXF01_13210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXF01_13240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LXF01_13245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXF01_13255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LXF01_13265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LXF01_13270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LXF01_13280	COG0625	glutathione transferase activity
LXF01_13285	COG2969	positive regulation of protein catabolic process
LXF01_13355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXF01_13360	COG1764	response to oxidative stress
LXF01_13395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXF01_13395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXF01_13410	COG0037	tRNA processing
LXF01_13420	COG0248	Ppx GppA phosphatase
LXF01_13445	COG0072	phenylalanine-tRNA ligase activity
LXF01_13495	COG1238	metal cluster binding
LXF01_13510	COG0625	glutathione transferase activity
LXF01_13520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LXF01_13530	COG0069	glutamate synthase activity
LXF01_13545	COG0318	PFAM AMP-dependent synthetase and ligase
LXF01_13550	COG3028	Belongs to the UPF0307 family
LXF01_13555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXF01_13560	COG1660	Displays ATPase and GTPase activities
LXF01_13575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXF01_13580	COG0617	tRNA 3'-terminal CCA addition
LXF01_13585	COG1596	polysaccharide export
LXF01_13585	COG1555	photosystem II stabilization
LXF01_13590	COG3956	TIGRFAM MazG family protein
LXF01_13620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXF01_13640	COG1426	Protein conserved in bacteria
LXF01_13675	COG4585	Histidine kinase
LXF01_13710	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LXF01_13715	COG0440	acetolactate synthase activity
LXF01_13720	COG0028	Belongs to the TPP enzyme family
LXF01_13740	COG1466	dna polymerase III delta subunit
LXF01_13745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXF01_13750	COG0577	efflux transmembrane transporter activity
LXF01_13750	COG1136	(ABC) transporter
LXF01_13755	COG1538	Outer membrane efflux protein
LXF01_13780	COG1388	LysM domain
LXF01_13780	COG3942	CHAP domain
LXF01_13795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LXF01_13805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LXF01_13810	COG1162	GTPase activity
LXF01_13820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LXF01_13825	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LXF01_13835	COG0084	hydrolase, TatD family'
LXF01_13850	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LXF01_13860	COG0793	Belongs to the peptidase S41A family
LXF01_13875	COG2267	carboxylic ester hydrolase activity
LXF01_13885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LXF01_13890	COG0280	phosphate acetyltransferase
LXF01_13890	COG0857	belongs to the CobB CobQ family
LXF01_13900	COG3540	Alkaline phosphatase
LXF01_13930	COG0740	serine-type endopeptidase activity
LXF01_13940	COG4771	TonB-dependent receptor
LXF01_13945	COG4774	siderophore transport
LXF01_13960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXF01_13970	COG2813	Specifically methylates the guanine in position
LXF01_13970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXF01_14045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LXF01_14085	COG0788	formyltetrahydrofolate deformylase activity
LXF01_14110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXF01_14110	COG4651	solute:proton antiporter activity
LXF01_14140	COG0210	DNA helicase
LXF01_14150	COG1929	Belongs to the glycerate kinase type-1 family
LXF01_14185	COG2900	Belongs to the SlyX family
LXF01_14190	COG0488	(ABC) transporter
LXF01_14195	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_14200	COG1560	Kdo2-lipid A biosynthetic process
LXF01_14235	COG0252	asparaginase activity
LXF01_14265	COG0473	3-isopropylmalate dehydrogenase activity
LXF01_14280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LXF01_14295	COG0583	DNA-binding transcription factor activity
LXF01_14315	COG0494	nUDIX hydrolase
LXF01_14345	COG1960	acyl-CoA dehydrogenase activity
LXF01_14360	COG0753	catalase activity
LXF01_14380	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXF01_14385	COG3384	dioxygenase
LXF01_14390	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_14405	COG4638	Rieske (2fe-2S)
LXF01_14410	COG0583	DNA-binding transcription factor activity
LXF01_14425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXF01_14430	COG4569	acetaldehyde dehydrogenase (acetylating) activity
LXF01_14435	COG3971	2-oxopent-4-enoate hydratase activity
LXF01_14450	COG1530	ribonuclease E activity
LXF01_14455	COG0318	PFAM AMP-dependent synthetase and ligase
LXF01_14485	COG1983	PspC domain protein
LXF01_14490	COG0517	IMP dehydrogenase activity
LXF01_14490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LXF01_14490	COG0617	tRNA 3'-terminal CCA addition
LXF01_14505	COG0752	glycyl-tRNA synthetase alpha subunit
LXF01_14510	COG0751	glycine-tRNA ligase activity
LXF01_14545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXF01_14575	COG0493	'glutamate synthase
LXF01_14585	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LXF01_14590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXF01_14605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXF01_14615	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LXF01_14615	COG0644	oxidoreductase
LXF01_14635	COG0425	Belongs to the sulfur carrier protein TusA family
LXF01_14640	COG4535	Mg2 and Co2 transporter CorC
LXF01_14645	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LXF01_14650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXF01_14670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXF01_14680	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LXF01_14705	COG0789	Transcriptional regulator
LXF01_14710	COG2841	Protein conserved in bacteria
LXF01_14715	COG0598	Magnesium transport protein CorA
LXF01_14730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXF01_14735	COG1074	ATP-dependent DNA helicase activity
LXF01_14740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LXF01_14770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LXF01_14810	COG0427	acetyl-CoA hydrolase
LXF01_14820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXF01_14860	COG0326	Molecular chaperone. Has ATPase activity
LXF01_14870	COG3047	cAMP biosynthetic process
LXF01_14875	COG2056	Na+-H+ antiporter family
LXF01_14900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LXF01_14905	COG0085	RNA polymerase activity
LXF01_14915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LXF01_14920	COG0081	regulation of translation
LXF01_14935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXF01_14975	COG0546	phosphoglycolate phosphatase activity
LXF01_15025	COG0181	hydroxymethylbilane synthase activity
LXF01_15035	COG3275	phosphorelay sensor kinase activity
LXF01_15050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXF01_15060	COG0322	excinuclease ABC activity
LXF01_15075	COG3706	GGDEF domain
LXF01_15110	COG3706	GGDEF domain
LXF01_15130	COG2226	methyltransferase
LXF01_15165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LXF01_15175	COG3152	Membrane
LXF01_15195	COG0697	spore germination
LXF01_15205	COG1278	Cold shock
LXF01_15210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXF01_15230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LXF01_15250	COG3158	transport of potassium into the cell
LXF01_15275	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LXF01_15285	COG1335	isochorismatase
LXF01_15290	COG0583	DNA-binding transcription factor activity
LXF01_15300	COG0629	single-stranded DNA binding
LXF01_15380	COG4221	oxidoreductase activity
LXF01_15415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LXF01_15540	COG2814	Major facilitator Superfamily
LXF01_15550	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXF01_15550	COG0351	phosphomethylpyrimidine kinase
LXF01_15550	COG0352	thiamine-phosphate diphosphorylase activity
LXF01_15610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXF01_15615	COG3162	membrane
LXF01_15620	COG2205	protein histidine kinase activity
LXF01_15620	COG0784	Response regulator, receiver
LXF01_15635	COG0431	NADPH-dependent FMN reductase
LXF01_15640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXF01_15645	COG0415	Belongs to the DNA photolyase family
LXF01_15650	COG0307	riboflavin synthase, alpha
LXF01_15660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXF01_15670	COG0668	transmembrane transport
LXF01_15675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXF01_15680	COG1519	Transferase
LXF01_15685	COG1902	pentaerythritol trinitrate reductase activity
LXF01_15710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LXF01_15715	COG0259	pyridoxamine-phosphate oxidase activity
LXF01_15735	COG0426	domain, Protein
LXF01_15735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXF01_15740	COG2119	membrane
LXF01_15775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXF01_15785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LXF01_15795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXF01_15805	COG0189	ligase activity
LXF01_15810	COG3706	GGDEF domain
LXF01_15825	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXF01_15830	COG3657	addiction module killer protein
LXF01_15840	COG0583	DNA-binding transcription factor activity
LXF01_15850	COG0708	Exodeoxyribonuclease III
LXF01_15855	COG1393	Belongs to the ArsC family
LXF01_15875	COG3706	GGDEF domain
LXF01_15955	COG3150	esterase
LXF01_15965	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LXF01_15970	COG2918	glutathione biosynthetic process
LXF01_15985	COG2733	membrane
LXF01_16030	COG0753	catalase activity
LXF01_16050	COG3830	Belongs to the UPF0237 family
LXF01_16050	COG0560	Phosphoserine phosphatase
LXF01_16065	COG0385	Bile acid
LXF01_16070	COG1335	isochorismatase
LXF01_16080	COG2814	Major facilitator Superfamily
LXF01_16085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXF01_16095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LXF01_16100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LXF01_16110	COG1683	Conserved Protein
LXF01_16115	COG2983	Belongs to the UPF0260 family
LXF01_16120	COG5487	UPF0391 membrane protein
LXF01_16130	COG3023	N-Acetylmuramoyl-L-alanine amidase
LXF01_16160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LXF01_16165	COG0546	phosphoglycolate phosphatase activity
LXF01_16170	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_16195	COG0675	Transposase, IS605 OrfB family
LXF01_16200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LXF01_16200	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LXF01_16205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXF01_16210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXF01_16215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXF01_16220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXF01_16225	COG1116	anion transmembrane transporter activity
LXF01_16230	COG1309	transcriptional regulator
LXF01_16250	COG0196	riboflavin kinase activity
LXF01_16255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXF01_16265	COG1047	Peptidyl-prolyl cis-trans
LXF01_16295	COG2133	pyrroloquinoline quinone binding
LXF01_16300	COG0693	protein deglycase activity
LXF01_16320	COG2814	Major facilitator Superfamily
LXF01_16365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXF01_16370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LXF01_16375	COG2951	lytic endotransglycosylase activity
LXF01_16380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LXF01_16400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXF01_16415	COG2388	GCN5-related N-acetyl-transferase
LXF01_16420	COG2814	Major facilitator Superfamily
LXF01_16425	COG0861	Integral membrane protein TerC family
LXF01_16435	COG0402	S-adenosylhomocysteine deaminase activity
LXF01_16450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXF01_16455	COG1230	cation diffusion facilitator family transporter
LXF01_16480	COG0706	membrane insertase activity
LXF01_16485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LXF01_16490	COG0594	ribonuclease P activity
LXF01_16500	COG1192	Involved in chromosome partitioning
LXF01_16505	COG1475	DNA binding
LXF01_16515	COG2814	Major facilitator Superfamily
LXF01_16530	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXF01_16540	COG0154	amidase activity
LXF01_16565	COG1028	Short-chain dehydrogenase reductase Sdr
LXF01_16575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXF01_16585	COG0154	amidase activity
LXF01_16595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXF01_16600	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXF01_16605	COG4829	muconolactone delta-isomerase
LXF01_16610	COG4948	Mandelate Racemase Muconate Lactonizing
LXF01_16615	COG0583	DNA-binding transcription factor activity
LXF01_16620	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LXF01_16625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXF01_16630	COG3485	protocatechuate 3,4-dioxygenase
LXF01_16650	COG0411	ABC transporter
LXF01_16660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LXF01_16740	COG1309	transcriptional regulator
LXF01_16750	COG3077	Addiction module antitoxin, RelB DinJ family
LXF01_16755	COG1794	racemase activity, acting on amino acids and derivatives
LXF01_16815	COG0582	viral genome integration into host DNA
LXF01_16830	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LXF01_16835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXF01_16865	COG0745	RESPONSE REGULATOR receiver
LXF01_16870	COG0642	Histidine kinase
LXF01_16885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LXF01_16910	COG2816	NAD+ diphosphatase activity
LXF01_16915	COG3046	protein related to deoxyribodipyrimidine photolyase
LXF01_16945	COG4191	Histidine kinase
LXF01_16970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXF01_16990	COG4638	Rieske (2fe-2S)
LXF01_17010	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LXF01_17010	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LXF01_17035	COG0514	ATP-dependent DNA helicase (RecQ)
LXF01_17145	COG0582	viral genome integration into host DNA
LXF01_17230	COG4974	Belongs to the 'phage' integrase family
LXF01_17315	COG0582	viral genome integration into host DNA
LXF01_17345	COG0488	(ABC) transporter
LXF01_17375	COG1192	Involved in chromosome partitioning
LXF01_17380	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LXF01_17405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXF01_17440	COG3077	Addiction module antitoxin, RelB DinJ family