locus-tag	class	description
CDG62_00245	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG62_00305	COG1192	Involved in chromosome partitioning
CDG62_00460	COG3173	Aminoglycoside phosphotransferase
CDG62_00465	COG3328	transposase activity
CDG62_00475	COG2801	Transposase and inactivated derivatives
CDG62_00565	COG4115	mRNA cleavage
CDG62_00575	COG0488	(ABC) transporter
CDG62_00585	COG2801	Transposase and inactivated derivatives
CDG62_00685	COG2801	Transposase and inactivated derivatives
CDG62_00700	COG3316	Transposase and inactivated derivatives
CDG62_00715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG62_00720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDG62_00730	COG0542	response to heat
CDG62_00845	COG1373	ATPase (AAA superfamily
CDG62_00855	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_00885	COG1324	tolerance protein
CDG62_00890	COG0673	inositol 2-dehydrogenase activity
CDG62_00910	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_00950	COG3316	Transposase and inactivated derivatives
CDG62_00975	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CDG62_01065	COG4783	chaperone-mediated protein folding
CDG62_01280	COG1538	Outer membrane efflux protein
CDG62_01290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_01295	COG1230	cation diffusion facilitator family transporter
CDG62_01305	COG0640	Transcriptional regulator
CDG62_01315	COG0789	Transcriptional regulator
CDG62_01425	COG1192	Involved in chromosome partitioning
CDG62_01430	COG1475	DNA binding
CDG62_01605	COG2009	succinate dehydrogenase
CDG62_01625	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDG62_01635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDG62_01690	COG0625	glutathione transferase activity
CDG62_01695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_01720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_01765	COG3293	Transposase
CDG62_01790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG62_01850	COG1132	(ABC) transporter
CDG62_01935	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_01945	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_02110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG62_02165	COG1525	nuclease
CDG62_02210	COG4977	sequence-specific DNA binding
CDG62_02210	COG1917	Cupin 2, conserved barrel domain protein
CDG62_02215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_02225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG62_02230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_02245	COG0183	Belongs to the thiolase family
CDG62_02250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_02255	COG3706	GGDEF domain
CDG62_02320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDG62_02345	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDG62_02350	COG3421	Type III restriction
CDG62_02390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDG62_02490	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDG62_02525	COG0789	Transcriptional regulator
CDG62_02585	COG3316	Transposase and inactivated derivatives
CDG62_02600	COG0210	DNA helicase
CDG62_02620	COG0583	DNA-binding transcription factor activity
CDG62_02625	COG2814	Major facilitator Superfamily
CDG62_02655	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_02670	COG3316	Transposase and inactivated derivatives
CDG62_02680	COG3316	Transposase and inactivated derivatives
CDG62_02695	COG1538	Outer membrane efflux protein
CDG62_02700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_02710	COG0745	RESPONSE REGULATOR receiver
CDG62_02715	COG2205	protein histidine kinase activity
CDG62_02730	COG2801	Transposase and inactivated derivatives
CDG62_02735	COG3173	Aminoglycoside phosphotransferase
CDG62_02745	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG62_02750	COG3657	addiction module killer protein
CDG62_02865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG62_02885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG62_02890	COG0592	DNA-directed DNA polymerase activity
CDG62_02900	COG0187	DNA topoisomerase II activity
CDG62_02910	COG0488	(ABC) transporter
CDG62_02980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG62_03010	COG2814	Major facilitator Superfamily
CDG62_03020	COG0733	neurotransmitter:sodium symporter activity
CDG62_03065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDG62_03065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDG62_03080	COG0129	dihydroxy-acid dehydratase activity
CDG62_03090	COG4774	siderophore transport
CDG62_03100	COG0583	DNA-binding transcription factor activity
CDG62_03105	COG2233	PERMEase
CDG62_03115	COG1309	transcriptional regulator
CDG62_03135	COG0484	heat shock protein binding
CDG62_03145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDG62_03160	COG0436	Aminotransferase
CDG62_03165	COG1064	alcohol dehydrogenase
CDG62_03170	COG2818	Glycosylase
CDG62_03200	COG5487	UPF0391 membrane protein
CDG62_03205	COG2983	Belongs to the UPF0260 family
CDG62_03210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDG62_03215	COG1280	lysine exporter protein (LysE YggA)
CDG62_03220	COG1522	sequence-specific DNA binding
CDG62_03230	COG4160	amino acid transport
CDG62_03235	COG4215	(ABC) transporter
CDG62_03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDG62_03260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG62_03265	COG1335	isochorismatase
CDG62_03270	COG0385	Bile acid
CDG62_03340	COG0534	Mate efflux family protein
CDG62_03345	COG0436	Aminotransferase
CDG62_03350	COG2733	membrane
CDG62_03365	COG2918	glutathione biosynthetic process
CDG62_03370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDG62_03380	COG3150	esterase
CDG62_03395	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDG62_03410	COG0410	ABC transporter
CDG62_03465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDG62_03480	COG1393	Belongs to the ArsC family
CDG62_03485	COG0708	Exodeoxyribonuclease III
CDG62_03495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG62_03510	COG1846	Transcriptional regulator
CDG62_03515	COG0386	Belongs to the glutathione peroxidase family
CDG62_03520	COG0189	ligase activity
CDG62_03530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG62_03540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDG62_03550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG62_03580	COG2119	membrane
CDG62_03585	COG0426	domain, Protein
CDG62_03585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_03610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDG62_03635	COG1902	pentaerythritol trinitrate reductase activity
CDG62_03640	COG1519	Transferase
CDG62_03645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG62_03650	COG0668	transmembrane transport
CDG62_03655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG62_03665	COG0579	oxidoreductase
CDG62_03675	COG0307	riboflavin synthase, alpha
CDG62_03680	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_03695	COG0431	NADPH-dependent FMN reductase
CDG62_03710	COG0784	Response regulator, receiver
CDG62_03710	COG2205	protein histidine kinase activity
CDG62_03715	COG3162	membrane
CDG62_03720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG62_03730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG62_03745	COG3706	GGDEF domain
CDG62_03765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG62_03765	COG0351	phosphomethylpyrimidine kinase
CDG62_03765	COG0352	thiamine-phosphate diphosphorylase activity
CDG62_03775	COG2814	Major facilitator Superfamily
CDG62_03780	COG0629	single-stranded DNA binding
CDG62_03790	COG0583	DNA-binding transcription factor activity
CDG62_03795	COG1301	dicarboxylic acid transport
CDG62_03810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDG62_03815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_03820	COG0450	alkyl hydroperoxide reductase
CDG62_03830	COG1335	isochorismatase
CDG62_03840	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG62_03880	COG0556	nucleotide-excision repair
CDG62_03885	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDG62_03910	COG0582	viral genome integration into host DNA
CDG62_03940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDG62_03965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDG62_03970	COG1278	Cold shock
CDG62_03985	COG0531	amino acid
CDG62_03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG62_04020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG62_04055	COG0427	acetyl-CoA hydrolase
CDG62_04060	COG2205	protein histidine kinase activity
CDG62_04065	COG0745	RESPONSE REGULATOR receiver
CDG62_04085	COG4221	oxidoreductase activity
CDG62_04095	COG0488	(ABC) transporter
CDG62_04115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG62_04130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG62_04150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDG62_04155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG62_04165	COG2226	methyltransferase
CDG62_04215	COG0069	glutamate synthase activity
CDG62_04215	COG0067	glutamate synthase
CDG62_04215	COG0070	glutamate synthase
CDG62_04220	COG0493	'glutamate synthase
CDG62_04230	COG1704	LemA family
CDG62_04235	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDG62_04250	COG3307	-O-antigen
CDG62_04275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG62_04280	COG1758	RNA polymerase activity
CDG62_04285	COG0194	GDP metabolic process
CDG62_04330	COG0228	four-way junction DNA binding
CDG62_04335	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG62_04340	COG0336	Belongs to the RNA methyltransferase TrmD family
CDG62_04345	COG0335	large ribosomal subunit rRNA binding
CDG62_04360	COG5380	lipid catabolic process
CDG62_04365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG62_04380	COG5006	permease, DMT superfamily
CDG62_04385	COG5006	permease, DMT superfamily
CDG62_04390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG62_04395	COG0277	FAD linked oxidase domain protein
CDG62_04405	COG2197	response regulator
CDG62_04410	COG0477	Major facilitator Superfamily
CDG62_04420	COG2814	Major facilitator Superfamily
CDG62_04425	COG1289	transmembrane transporter activity
CDG62_04430	COG2032	superoxide dismutase activity
CDG62_04435	COG0628	permease
CDG62_04440	COG1192	Involved in chromosome partitioning
CDG62_04450	COG2226	methyltransferase
CDG62_04465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG62_04470	COG0254	rRNA binding
CDG62_04475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG62_04485	COG0534	Mate efflux family protein
CDG62_04495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG62_04520	COG1960	acyl-CoA dehydrogenase activity
CDG62_04530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDG62_04545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG62_04570	COG1127	ABC transporter
CDG62_04575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG62_04580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG62_04585	COG2854	intermembrane phospholipid transfer
CDG62_04595	COG0598	Magnesium transport protein CorA
CDG62_04610	COG1040	competence protein
CDG62_04615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDG62_04630	COG2937	Belongs to the GPAT DAPAT family
CDG62_04635	COG1946	Acyl-CoA thioesterase
CDG62_04640	COG1301	dicarboxylic acid transport
CDG62_04655	COG1959	2 iron, 2 sulfur cluster binding
CDG62_04660	COG1017	nitric oxide dioxygenase activity
CDG62_04660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG62_04670	COG0300	oxidoreductase activity
CDG62_04675	COG0433	COG0433 Predicted ATPase
CDG62_04695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDG62_04700	COG0088	Forms part of the polypeptide exit tunnel
CDG62_04715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG62_04755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDG62_04765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG62_04770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDG62_04780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG62_04800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDG62_04805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDG62_04810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDG62_04820	COG0202	RNA polymerase activity
CDG62_04825	COG0203	ribosomal protein L17
CDG62_04830	COG2072	flavoprotein involved in K transport
CDG62_04840	COG1960	acyl-CoA dehydrogenase activity
CDG62_04845	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDG62_04875	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CDG62_04880	COG0339	signal peptide processing
CDG62_04885	COG2720	vancomycin resistance protein
CDG62_04890	COG0557	exoribonuclease II activity
CDG62_04920	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG62_04935	COG1295	ribonuclease BN
CDG62_04950	COG3706	GGDEF domain
CDG62_04975	COG4773	Receptor
CDG62_04985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDG62_04990	COG1702	phosphate starvation-inducible protein PhoH
CDG62_04995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDG62_05000	COG0739	heme binding
CDG62_05000	COG0741	lytic transglycosylase activity
CDG62_05000	COG1196	nuclear chromosome segregation
CDG62_05035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDG62_05040	COG1183	phosphatidylcholine synthase activity
CDG62_05080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_05090	COG3453	Protein conserved in bacteria
CDG62_05090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG62_05105	COG1607	acyl-coa hydrolase
CDG62_05120	COG1666	GTP binding
CDG62_05140	COG2350	Protein conserved in bacteria
CDG62_05150	COG0613	PHP domain protein
CDG62_05155	COG3781	membrane
CDG62_05165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDG62_05190	COG1162	GTPase activity
CDG62_05195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG62_05210	COG1538	Outer membrane efflux protein
CDG62_05215	COG1136	(ABC) transporter
CDG62_05215	COG0577	efflux transmembrane transporter activity
CDG62_05220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_05250	COG0028	Belongs to the TPP enzyme family
CDG62_05255	COG0440	acetolactate synthase activity
CDG62_05290	COG0438	transferase activity, transferring glycosyl groups
CDG62_05320	COG1426	Protein conserved in bacteria
CDG62_05340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG62_05365	COG1862	Preprotein translocase
CDG62_05375	COG1704	LemA family
CDG62_05385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDG62_05395	COG5002	protein histidine kinase activity
CDG62_05400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG62_05435	COG0438	transferase activity, transferring glycosyl groups
CDG62_05455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDG62_05470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG62_05475	COG0463	Glycosyl transferase, family 2
CDG62_05500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG62_05530	COG3223	Belongs to the PsiE family
CDG62_05535	COG1960	acyl-CoA dehydrogenase activity
CDG62_05540	COG1960	acyl-CoA dehydrogenase activity
CDG62_05550	COG2205	protein histidine kinase activity
CDG62_05555	COG0745	RESPONSE REGULATOR receiver
CDG62_05560	COG1113	amino acid transport
CDG62_05565	COG2315	Protein conserved in bacteria
CDG62_05570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDG62_05590	COG2096	Adenosyltransferase
CDG62_05595	COG4206	TonB-dependent receptor
CDG62_05605	COG0133	tryptophan synthase activity
CDG62_05620	COG3083	sulfuric ester hydrolase activity
CDG62_05645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDG62_05650	COG0285	dihydrofolate synthase activity
CDG62_05670	COG0450	alkyl hydroperoxide reductase
CDG62_05690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG62_05695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG62_05725	COG2199	diguanylate cyclase activity
CDG62_05795	COG2969	positive regulation of protein catabolic process
CDG62_05800	COG0625	glutathione transferase activity
CDG62_05810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG62_05815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG62_05820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDG62_05825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG62_05830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG62_05855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG62_05865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG62_05870	COG1408	metallophosphoesterase
CDG62_05880	COG0477	Major facilitator Superfamily
CDG62_05885	COG1272	protein, Hemolysin III
CDG62_05910	COG0183	Belongs to the thiolase family
CDG62_05915	COG2207	Transcriptional regulator
CDG62_05920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG62_05935	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_05955	COG0183	Belongs to the thiolase family
CDG62_05965	COG2885	chlorophyll binding
CDG62_05965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CDG62_05970	COG0833	amino acid
CDG62_05975	COG2813	Specifically methylates the guanine in position
CDG62_05980	COG2233	PERMEase
CDG62_05990	COG1970	mechanosensitive ion channel activity
CDG62_06000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG62_06010	COG3659	wide pore channel activity
CDG62_06015	COG1902	pentaerythritol trinitrate reductase activity
CDG62_06050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDG62_06100	COG0346	lactoylglutathione lyase activity
CDG62_06105	COG0564	pseudouridine synthase activity
CDG62_06125	COG3189	MarR family transcriptional regulator
CDG62_06130	COG2824	Alkylphosphonate utilization operon protein PhnA
CDG62_06140	COG3422	double-strand break repair
CDG62_06180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDG62_06200	COG0730	response to heat
CDG62_06210	COG1196	nuclear chromosome segregation
CDG62_06215	COG3115	cell septum assembly
CDG62_06220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG62_06225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDG62_06230	COG4774	siderophore transport
CDG62_06245	COG2193	ferroxidase activity
CDG62_06250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG62_06255	COG0596	Alpha beta hydrolase
CDG62_06255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG62_06255	COG2226	methyltransferase
CDG62_06270	COG4106	trans-aconitate 2-methyltransferase activity
CDG62_06300	COG4206	TonB-dependent receptor
CDG62_06340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG62_06345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG62_06355	COG0009	L-threonylcarbamoyladenylate synthase
CDG62_06360	COG3101	peptidyl-lysine hydroxylation
CDG62_06365	COG1399	metal-binding, possibly nucleic acid-binding protein
CDG62_06370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDG62_06380	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_06390	COG1652	LysM domain
CDG62_06395	COG1802	Transcriptional regulator
CDG62_06425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG62_06430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDG62_06430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG62_06435	COG0745	RESPONSE REGULATOR receiver
CDG62_06440	COG2205	protein histidine kinase activity
CDG62_06450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG62_06470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDG62_06485	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG62_06495	COG0713	ATP synthesis coupled electron transport
CDG62_06500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG62_06505	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG62_06515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDG62_06520	COG1278	Cold shock
CDG62_06525	COG1278	Cold shock
CDG62_06530	COG0583	DNA-binding transcription factor activity
CDG62_06555	COG0525	valine-tRNA ligase activity
CDG62_06565	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_06575	COG0393	Putative heavy-metal-binding
CDG62_06580	COG0393	Putative heavy-metal-binding
CDG62_06585	COG1538	Outer membrane efflux protein
CDG62_06595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_06600	COG0671	phosphoesterase, PA-phosphatase related
CDG62_06620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDG62_06635	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDG62_06645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDG62_06650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG62_06650	COG1648	precorrin-2 dehydrogenase activity
CDG62_06655	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG62_06665	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_06675	COG0531	amino acid
CDG62_06690	COG0321	lipoyl(octanoyl) transferase activity
CDG62_06695	COG2921	Belongs to the UPF0250 family
CDG62_06725	COG0586	Pfam SNARE associated Golgi protein
CDG62_06750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG62_06780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDG62_06810	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDG62_06825	COG0358	DNA primase activity
CDG62_06835	COG0564	pseudouridine synthase activity
CDG62_06860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG62_06885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG62_06885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG62_06900	COG0300	oxidoreductase activity
CDG62_06905	COG2072	flavoprotein involved in K transport
CDG62_06915	COG2009	succinate dehydrogenase
CDG62_06920	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDG62_06925	COG1053	succinate dehydrogenase
CDG62_06930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG62_06945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_06955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDG62_06965	COG2268	Band 7 protein
CDG62_06970	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG62_06980	COG2354	Protein conserved in bacteria
CDG62_06985	COG2321	neutral zinc metallopeptidase
CDG62_07000	COG3695	enzyme binding
CDG62_07030	COG0505	Belongs to the CarA family
CDG62_07055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG62_07060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG62_07100	COG2851	Citrate transporter
CDG62_07105	COG1253	flavin adenine dinucleotide binding
CDG62_07135	COG2239	Acts as a magnesium transporter
CDG62_07150	COG0501	Belongs to the peptidase M48B family
CDG62_07155	COG1196	nuclear chromosome segregation
CDG62_07155	COG0741	lytic transglycosylase activity
CDG62_07155	COG0739	heme binding
CDG62_07160	COG0037	tRNA processing
CDG62_07170	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CDG62_07175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG62_07205	COG1309	transcriptional regulator
CDG62_07220	COG1741	Belongs to the pirin family
CDG62_07240	COG3739	integral membrane protein
CDG62_07255	COG3706	GGDEF domain
CDG62_07265	COG0302	gtp cyclohydrolase
CDG62_07275	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_07280	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_07300	COG0134	indole-3-glycerol-phosphate synthase activity
CDG62_07305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG62_07310	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG62_07325	COG3161	chorismate lyase activity
CDG62_07330	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG62_07370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG62_07380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG62_07385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG62_07400	COG1115	amino acid carrier protein
CDG62_07405	COG1113	amino acid transport
CDG62_07415	COG0019	diaminopimelate decarboxylase activity
CDG62_07420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDG62_07425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDG62_07435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDG62_07440	COG1522	sequence-specific DNA binding
CDG62_07445	COG1280	lysine exporter protein (LysE YggA)
CDG62_07480	COG0842	Transport permease protein
CDG62_07485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_07500	COG2175	clavaminate synthase activity
CDG62_07515	COG0024	Methionine aminopeptidase
CDG62_07520	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG62_07555	COG2951	lytic endotransglycosylase activity
CDG62_07570	COG0842	Transport permease protein
CDG62_07575	COG1131	(ABC) transporter
CDG62_07585	COG0303	'Molybdopterin
CDG62_07590	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG62_07590	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDG62_07600	COG0243	molybdopterin cofactor binding
CDG62_07605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDG62_07615	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDG62_07620	COG4149	molybdate abc transporter
CDG62_07635	COG2169	Transcriptional regulator
CDG62_07640	COG0235	Class ii aldolase
CDG62_07645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG62_07650	COG0697	spore germination
CDG62_07655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG62_07655	COG0475	glutathione-regulated potassium exporter activity
CDG62_07660	COG3706	GGDEF domain
CDG62_07700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG62_07725	COG3634	alkyl hydroperoxide reductase activity
CDG62_07730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG62_07740	COG0789	Transcriptional regulator
CDG62_07775	COG1720	tRNA m6t6A37 methyltransferase activity
CDG62_07805	COG0745	RESPONSE REGULATOR receiver
CDG62_07810	COG0642	Histidine kinase
CDG62_07820	COG0494	nUDIX hydrolase
CDG62_07830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG62_07835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG62_07840	COG3139	Protein of unknown function (DUF1315)
CDG62_07855	COG1301	dicarboxylic acid transport
CDG62_07860	COG1960	acyl-CoA dehydrogenase activity
CDG62_07865	COG0693	protein deglycase activity
CDG62_07875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDG62_07880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG62_07910	COG0415	Belongs to the DNA photolyase family
CDG62_07920	COG2252	PERMEase
CDG62_07925	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG62_07935	COG3038	cytochrome b561
CDG62_07950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG62_07970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDG62_07985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDG62_07990	COG1522	sequence-specific DNA binding
CDG62_07995	COG1522	sequence-specific DNA binding
CDG62_08000	COG1335	isochorismatase
CDG62_08015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG62_08030	COG0667	Aldo Keto reductase
CDG62_08040	COG1765	OsmC-like protein
CDG62_08065	COG0540	Belongs to the ATCase OTCase family
CDG62_08085	COG2031	fatty acid transporter
CDG62_08090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_08115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG62_08120	COG1960	acyl-CoA dehydrogenase activity
CDG62_08125	COG1309	transcriptional regulator
CDG62_08130	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_08160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG62_08170	COG0659	secondary active sulfate transmembrane transporter activity
CDG62_08175	COG0625	glutathione transferase activity
CDG62_08180	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG62_08205	COG2363	Small membrane protein
CDG62_08220	COG1278	Cold shock
CDG62_08225	COG0513	Belongs to the DEAD box helicase family
CDG62_08235	COG0778	Nitroreductase
CDG62_08290	COG4783	chaperone-mediated protein folding
CDG62_08295	COG1610	YqeY-like protein
CDG62_08300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDG62_08310	COG1335	isochorismatase
CDG62_08325	COG0515	serine threonine protein kinase
CDG62_08325	COG2815	serine threonine protein kinase
CDG62_08365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG62_08370	COG0450	alkyl hydroperoxide reductase
CDG62_08375	COG1643	Atp-dependent helicase
CDG62_08395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_08395	COG1116	anion transmembrane transporter activity
CDG62_08405	COG2223	nitrite transmembrane transporter activity
CDG62_08410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_08415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_08420	COG0243	molybdopterin cofactor binding
CDG62_08430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG62_08465	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDG62_08470	COG0406	alpha-ribazole phosphatase activity
CDG62_08480	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG62_08480	COG0517	IMP dehydrogenase activity
CDG62_08485	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDG62_08495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDG62_08500	COG1137	ATPase activity
CDG62_08530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDG62_08570	COG2011	ABC-type metal ion transport system permease component
CDG62_08575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG62_08580	COG1464	Belongs to the NlpA lipoprotein family
CDG62_08585	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG62_08595	COG0151	Belongs to the GarS family
CDG62_08600	COG0138	bifunctional purine biosynthesis protein purh
CDG62_08605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG62_08635	COG0445	tRNA wobble uridine modification
CDG62_08645	COG2308	Evidence 4 Homologs of previously reported genes of
CDG62_08655	COG1305	Transglutaminase-like
CDG62_08670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG62_08675	COG0305	Participates in initiation and elongation during chromosome replication
CDG62_08690	COG0360	Binds together with S18 to 16S ribosomal RNA
CDG62_08710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDG62_08715	COG1845	cytochrome c oxidase, subunit III
CDG62_08720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG62_08725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG62_08755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_08770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDG62_08775	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG62_08780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG62_08785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_08815	COG1960	acyl-CoA dehydrogenase activity
CDG62_08820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG62_08835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDG62_08855	COG0477	Major facilitator Superfamily
CDG62_08860	COG0729	surface antigen
CDG62_08905	COG4773	Receptor
CDG62_08910	COG0786	glutamate:sodium symporter activity
CDG62_08920	COG1113	amino acid transport
CDG62_08950	COG0024	Methionine aminopeptidase
CDG62_08955	COG3328	transposase activity
CDG62_08960	COG0583	DNA-binding transcription factor activity
CDG62_08965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG62_08980	COG3852	Histidine kinase
CDG62_09000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG62_09005	COG0575	Belongs to the CDS family
CDG62_09020	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG62_09040	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_09055	COG2137	regulation of response to DNA damage stimulus
CDG62_09060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDG62_09065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDG62_09070	COG1011	Hydrolase
CDG62_09085	COG1218	3'(2'),5'-bisphosphate nucleotidase
CDG62_09110	COG0702	epimerase
CDG62_09115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG62_09125	COG2267	carboxylic ester hydrolase activity
CDG62_09135	COG1902	pentaerythritol trinitrate reductase activity
CDG62_09135	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG62_09150	COG2814	Major facilitator Superfamily
CDG62_09160	COG0583	DNA-binding transcription factor activity
CDG62_09180	COG0148	phosphopyruvate hydratase activity
CDG62_09195	COG0772	Belongs to the SEDS family
CDG62_09210	COG0579	oxidoreductase
CDG62_09220	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_09225	COG1309	transcriptional regulator
CDG62_09230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG62_09245	COG4890	Cyd operon protein YbgT
CDG62_09250	COG1294	oxidase, subunit
CDG62_09265	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG62_09275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG62_09295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG62_09300	COG0569	domain protein
CDG62_09310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG62_09315	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDG62_09325	COG3706	GGDEF domain
CDG62_09340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG62_09345	COG0542	response to heat
CDG62_09375	COG0372	Belongs to the citrate synthase family
CDG62_09385	COG2819	hydrolase of the alpha beta superfamily
CDG62_09390	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_09415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDG62_09415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDG62_09420	COG1254	Belongs to the acylphosphatase family
CDG62_09425	COG1047	Peptidyl-prolyl cis-trans
CDG62_09430	COG1252	NADH dehydrogenase
CDG62_09435	COG1686	Belongs to the peptidase S11 family
CDG62_09445	COG2351	hydroxyisourate hydrolase activity
CDG62_09610	COG5410	chromosome segregation
CDG62_09755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG62_09760	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_09780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG62_09805	COG0582	viral genome integration into host DNA
CDG62_09835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_09850	COG0612	Peptidase, M16
CDG62_09885	COG0352	thiamine-phosphate diphosphorylase activity
CDG62_09910	COG1942	4-Oxalocrotonate Tautomerase
CDG62_09915	COG0583	DNA-binding transcription factor activity
CDG62_09950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG62_09955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDG62_09965	COG0456	acetyltransferase
CDG62_09975	COG0519	Catalyzes the synthesis of GMP from XMP
CDG62_09975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG62_09985	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_09995	COG4302	ethanolamine ammonia-lyase activity
CDG62_10000	COG4303	Ethanolamine ammonia lyase large subunit
CDG62_10005	COG0531	amino acid
CDG62_10025	COG1454	alcohol dehydrogenase
CDG62_10035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG62_10040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG62_10045	COG2814	Major facilitator Superfamily
CDG62_10050	COG2707	UPF0756 membrane protein
CDG62_10055	COG1187	pseudouridine synthase activity
CDG62_10075	COG0802	atpase or kinase
CDG62_10080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDG62_10090	COG1923	regulation of RNA biosynthetic process
CDG62_10095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG62_10110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDG62_10120	COG1192	Involved in chromosome partitioning
CDG62_10125	COG1475	DNA binding
CDG62_10130	COG0811	peptide transport
CDG62_10140	COG1132	(ABC) transporter
CDG62_10145	COG1663	tetraacyldisaccharide 4'-kinase activity
CDG62_10165	COG0084	hydrolase, TatD family'
CDG62_10200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDG62_10210	COG0590	tRNA wobble adenosine to inosine editing
CDG62_10230	COG0776	regulation of translation
CDG62_10250	COG2431	L-lysine efflux transmembrane transporter activity
CDG62_10265	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDG62_10270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG62_10290	COG1253	flavin adenine dinucleotide binding
CDG62_10315	COG0308	aminopeptidase N
CDG62_10325	COG0589	response to stress
CDG62_10340	COG2076	Multidrug Resistance protein
CDG62_10345	COG1309	transcriptional regulator
CDG62_10350	COG3135	benzoate transporter
CDG62_10360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG62_10365	COG0583	DNA-binding transcription factor activity
CDG62_10380	COG0183	Belongs to the thiolase family
CDG62_10385	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_10405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDG62_10410	COG0824	Thioesterase
CDG62_10415	COG1454	alcohol dehydrogenase
CDG62_10420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG62_10440	COG0069	glutamate synthase activity
CDG62_10445	COG2197	response regulator
CDG62_10450	COG4585	Histidine kinase
CDG62_10455	COG2850	peptidyl-arginine hydroxylation
CDG62_10460	COG0424	maF-like protein
CDG62_10470	COG0126	phosphoglycerate kinase activity
CDG62_10485	COG0697	spore germination
CDG62_10510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_10520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG62_10525	COG3781	membrane
CDG62_10540	COG3328	transposase activity
CDG62_10565	COG0506	proline dehydrogenase activity
CDG62_10565	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG62_10565	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG62_10575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG62_10585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDG62_10615	COG0316	Belongs to the HesB IscA family
CDG62_10620	COG0822	iron-sulfur transferase activity
CDG62_10630	COG1959	2 iron, 2 sulfur cluster binding
CDG62_10645	COG0776	regulation of translation
CDG62_10650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG62_10675	COG0537	adenosine 5'-monophosphoramidase activity
CDG62_10720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG62_10725	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CDG62_10740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG62_10750	COG0133	tryptophan synthase activity
CDG62_10755	COG0517	IMP dehydrogenase activity
CDG62_10785	COG0612	Peptidase, M16
CDG62_10790	COG0552	protein localization to endoplasmic reticulum
CDG62_10840	COG1960	acyl-CoA dehydrogenase activity
CDG62_10845	COG1960	acyl-CoA dehydrogenase activity
CDG62_10895	COG2199	diguanylate cyclase activity
CDG62_10905	COG2814	Major facilitator Superfamily
CDG62_10910	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_10930	COG0864	Transcriptional regulator
CDG62_10955	COG1116	anion transmembrane transporter activity
CDG62_11000	COG0596	Alpha beta hydrolase
CDG62_11015	COG2909	trisaccharide binding
CDG62_11035	COG2267	carboxylic ester hydrolase activity
CDG62_11065	COG0583	DNA-binding transcription factor activity
CDG62_11095	COG4774	siderophore transport
CDG62_11115	COG0789	Transcriptional regulator
CDG62_11120	COG1902	pentaerythritol trinitrate reductase activity
CDG62_11125	COG3268	Saccharopine dehydrogenase
CDG62_11175	COG2814	Major facilitator Superfamily
CDG62_11180	COG0583	DNA-binding transcription factor activity
CDG62_11185	COG4948	Mandelate Racemase Muconate Lactonizing
CDG62_11190	COG4829	muconolactone delta-isomerase
CDG62_11200	COG4638	Rieske (2fe-2S)
CDG62_11205	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDG62_11210	COG0633	Ferredoxin
CDG62_11210	COG0543	2 iron, 2 sulfur cluster binding
CDG62_11215	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_11220	COG3135	benzoate transporter
CDG62_11225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG62_11230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_11235	COG0183	Belongs to the thiolase family
CDG62_11240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG62_11250	COG0511	ligase activity, forming carbon-carbon bonds
CDG62_11270	COG0439	Biotin carboxylase
CDG62_11285	COG0583	DNA-binding transcription factor activity
CDG62_11290	COG0183	Belongs to the thiolase family
CDG62_11300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG62_11310	COG2233	PERMEase
CDG62_11315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG62_11320	COG0251	oxidation-reduction process
CDG62_11325	COG1335	isochorismatase
CDG62_11330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_11335	COG0596	Alpha beta hydrolase
CDG62_11340	COG0640	Transcriptional regulator
CDG62_11360	COG3122	Protein conserved in bacteria
CDG62_11365	COG0668	transmembrane transport
CDG62_11375	COG1132	(ABC) transporter
CDG62_11390	COG2814	Major facilitator Superfamily
CDG62_11400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG62_11405	COG3300	MHYT domain
CDG62_11405	COG5001	Diguanylate cyclase
CDG62_11420	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG62_11425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG62_11445	COG3123	guanosine phosphorylase activity
CDG62_11470	COG0583	DNA-binding transcription factor activity
CDG62_11500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG62_11505	COG1846	Transcriptional regulator
CDG62_11515	COG3038	cytochrome b561
CDG62_11520	COG1484	DNA-dependent DNA replication
CDG62_11525	COG4584	PFAM Integrase catalytic
CDG62_11560	COG4372	Transposase
CDG62_11580	COG3328	transposase activity
CDG62_11585	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_11640	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CDG62_11665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG62_11670	COG0583	DNA-binding transcription factor activity
CDG62_11680	COG1346	cytolysis
CDG62_11695	COG2223	nitrite transmembrane transporter activity
CDG62_11720	COG4264	IucA IucC family
CDG62_11725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG62_11730	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_11735	COG2207	Transcriptional regulator
CDG62_11740	COG1944	ATP diphosphatase activity
CDG62_11745	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_11780	COG2801	Transposase and inactivated derivatives
CDG62_11795	COG0730	response to heat
CDG62_11800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG62_11840	COG0204	Acyl-transferase
CDG62_11850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDG62_11880	COG1464	Belongs to the NlpA lipoprotein family
CDG62_11885	COG1464	Belongs to the NlpA lipoprotein family
CDG62_11890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG62_11895	COG2011	ABC-type metal ion transport system permease component
CDG62_11900	COG0012	GTP binding
CDG62_11925	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDG62_11940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDG62_11965	COG0386	Belongs to the glutathione peroxidase family
CDG62_11970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG62_11975	COG0436	Aminotransferase
CDG62_11995	COG3634	alkyl hydroperoxide reductase activity
CDG62_12020	COG2070	2-Nitropropane dioxygenase
CDG62_12040	COG0604	alcohol dehydrogenase
CDG62_12115	COG1309	transcriptional regulator
CDG62_12140	COG0842	Transport permease protein
CDG62_12145	COG0842	Transport permease protein
CDG62_12150	COG1131	(ABC) transporter
CDG62_12185	COG1538	Outer membrane efflux protein
CDG62_12195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_12200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG62_12210	COG3712	iron ion homeostasis
CDG62_12230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG62_12235	COG0697	spore germination
CDG62_12250	COG1538	Outer membrane efflux protein
CDG62_12255	COG0463	Glycosyl transferase, family 2
CDG62_12255	COG0457	Tetratricopeptide repeat
CDG62_12310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_12320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_12330	COG0625	glutathione transferase activity
CDG62_12365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG62_12380	COG3316	Transposase and inactivated derivatives
CDG62_12400	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_12430	COG1324	tolerance protein
CDG62_12435	COG0673	inositol 2-dehydrogenase activity
CDG62_12455	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_12495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDG62_12515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG62_12545	COG2801	Transposase and inactivated derivatives
CDG62_12570	COG0714	Associated with various cellular activities
CDG62_12575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDG62_12580	COG2879	small protein
CDG62_12585	COG1966	Carbon starvation protein
CDG62_12590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG62_12610	COG0254	rRNA binding
CDG62_12635	COG1067	ATP-dependent peptidase activity
CDG62_12640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG62_12645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG62_12650	COG0616	signal peptide processing
CDG62_12655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG62_12665	COG0573	inorganic phosphate transmembrane transporter activity
CDG62_12670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDG62_12680	COG0076	glutamate decarboxylase activity
CDG62_12685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG62_12695	COG4772	TonB-dependent receptor
CDG62_12700	COG0671	phosphoesterase, PA-phosphatase related
CDG62_12715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDG62_12725	COG1733	regulation of RNA biosynthetic process
CDG62_12730	COG0702	epimerase
CDG62_12760	COG0556	nucleotide-excision repair
CDG62_12825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDG62_12830	COG1381	Involved in DNA repair and RecF pathway recombination
CDG62_12840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG62_12845	COG0571	ribonuclease III activity
CDG62_12855	COG0681	Belongs to the peptidase S26 family
CDG62_12870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG62_12890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDG62_12900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG62_12915	COG4208	sulfate ABC transporter
CDG62_12920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDG62_12925	COG0583	DNA-binding transcription factor activity
CDG62_12945	COG0602	queuosine metabolic process
CDG62_12950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDG62_12965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG62_12975	COG0583	DNA-binding transcription factor activity
CDG62_12980	COG2353	YceI-like domain
CDG62_12985	COG1056	cytidyltransferase-related domain
CDG62_12985	COG1051	belongs to the nudix hydrolase family
CDG62_12990	COG1024	Enoyl-CoA hydratase
CDG62_12995	COG0778	Nitroreductase
CDG62_13005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG62_13005	COG3323	Protein of unknown function (DUF1653)
CDG62_13015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG62_13015	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG62_13030	COG2255	four-way junction helicase activity
CDG62_13050	COG0824	Thioesterase
CDG62_13070	COG0823	Involved in the tonB-independent uptake of proteins
CDG62_13090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG62_13130	COG0628	permease
CDG62_13135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDG62_13140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDG62_13160	COG2333	competence protein COMEC
CDG62_13160	COG0658	competence protein
CDG62_13165	COG1136	(ABC) transporter
CDG62_13170	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDG62_13180	COG0697	spore germination
CDG62_13185	COG1671	Belongs to the UPF0178 family
CDG62_13195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG62_13200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG62_13245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG62_13250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDG62_13255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG62_13260	COG1716	ATPase activity
CDG62_13260	COG5001	Diguanylate cyclase
CDG62_13265	COG0281	malic enzyme
CDG62_13265	COG0280	phosphate acetyltransferase
CDG62_13290	COG1773	rubredoxin
CDG62_13295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG62_13340	COG1024	Enoyl-CoA hydratase
CDG62_13345	COG1960	acyl-CoA dehydrogenase activity
CDG62_13350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG62_13365	COG0583	DNA-binding transcription factor activity
CDG62_13390	COG3328	transposase activity
CDG62_13405	COG1902	pentaerythritol trinitrate reductase activity
CDG62_13405	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG62_13410	COG0277	FAD linked oxidase domain protein
CDG62_13420	COG2186	Transcriptional regulator
CDG62_13435	COG2203	Gaf domain
CDG62_13435	COG5001	Diguanylate cyclase
CDG62_13435	COG3706	GGDEF domain
CDG62_13435	COG4251	negative regulation of phosphorylation
CDG62_13440	COG0418	dihydroorotase activity
CDG62_13445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG62_13455	COG0833	amino acid
CDG62_13465	COG0833	amino acid
CDG62_13510	COG4172	Belongs to the ABC transporter superfamily
CDG62_13515	COG4239	(ABC) transporter, permease
CDG62_13520	COG4174	ABC transporter (Permease)
CDG62_13525	COG4166	transmembrane transport
CDG62_13530	COG0741	lytic transglycosylase activity
CDG62_13530	COG1388	LysM domain
CDG62_13535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG62_13570	COG0583	DNA-binding transcription factor activity
CDG62_13575	COG1388	LysM domain
CDG62_13575	COG4942	peptidase
CDG62_13585	COG0582	viral genome integration into host DNA
CDG62_13615	COG0753	catalase activity
CDG62_13645	COG1686	Belongs to the peptidase S11 family
CDG62_13650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG62_13655	COG0583	DNA-binding transcription factor activity
CDG62_13660	COG1335	isochorismatase
CDG62_13675	COG2915	High frequency lysogenization protein hflD homolog
CDG62_13695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG62_13700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG62_13710	COG3706	GGDEF domain
CDG62_13715	COG0006	proline dipeptidase activity
CDG62_13750	COG1234	tRNA 3'-trailer cleavage
CDG62_13755	COG4221	oxidoreductase activity
CDG62_13760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG62_13805	COG4399	Belongs to the UPF0754 family
CDG62_13820	COG4770	biotin carboxylase activity
CDG62_13840	COG1914	H( )-stimulated, divalent metal cation uptake system
CDG62_13850	COG2217	Heavy metal translocating P-type atpase
CDG62_13860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG62_13875	COG2234	aminopeptidase activity
CDG62_13885	COG3384	dioxygenase
CDG62_13895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG62_13900	COG2878	Part of a membrane complex involved in electron transport
CDG62_13905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDG62_13930	COG0768	penicillin binding
CDG62_13935	COG0742	ribosomal rna small subunit methyltransferase
CDG62_13950	COG0204	Acyl-transferase
CDG62_13960	COG3119	arylsulfatase activity
CDG62_13965	COG0641	radical SAM
CDG62_14015	COG0477	Major facilitator Superfamily
CDG62_14070	COG1695	Transcriptional regulator
CDG62_14090	COG0175	sulfate reduction
CDG62_14110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDG62_14115	COG1773	rubredoxin
CDG62_14120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_14130	COG0583	DNA-binding transcription factor activity
CDG62_14150	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDG62_14155	COG4181	ATPase activity
CDG62_14180	COG4771	TonB-dependent receptor
CDG62_14200	COG0306	phosphate transporter
CDG62_14240	COG2223	nitrite transmembrane transporter activity
CDG62_14250	COG0242	peptide deformylase activity
CDG62_14255	COG0477	Major facilitator Superfamily
CDG62_14295	COG0456	acetyltransferase
CDG62_14300	COG2199	diguanylate cyclase activity
CDG62_14300	COG2203	Gaf domain
CDG62_14310	COG4681	YaeQ
CDG62_14315	COG0523	cobalamin synthesis protein
CDG62_14330	COG1607	acyl-coa hydrolase
CDG62_14335	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG62_14345	COG1115	amino acid carrier protein
CDG62_14350	COG0786	glutamate:sodium symporter activity
CDG62_14370	COG2814	Major facilitator Superfamily
CDG62_14375	COG1289	transmembrane transporter activity
CDG62_14385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDG62_14455	COG2832	Protein of unknown function (DUF454)
CDG62_14470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG62_14480	COG0643	Histidine kinase
CDG62_14480	COG0643	Histidine kinase
CDG62_14480	COG2198	Histidine kinase
CDG62_14480	COG2198	Histidine kinase
CDG62_14485	COG0840	transmembrane signaling receptor activity
CDG62_14570	COG0489	protein tyrosine kinase activity
CDG62_14590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG62_14590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG62_14615	COG4716	Myosin-crossreactive antigen
CDG62_14645	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CDG62_14650	COG2081	HI0933 family
CDG62_14660	COG0668	transmembrane transport
CDG62_14680	COG0765	amino acid transport
CDG62_14685	COG0765	amino acid transport
CDG62_14690	COG1126	abc transporter atp-binding protein
CDG62_14700	COG0004	ammonium transporteR
CDG62_14715	COG0642	Histidine kinase
CDG62_14720	COG0745	RESPONSE REGULATOR receiver
CDG62_14745	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG62_14760	COG0142	geranyltranstransferase activity
CDG62_14765	COG2828	Protein conserved in bacteria
CDG62_14770	COG1113	amino acid transport
CDG62_14785	COG1113	amino acid transport
CDG62_14805	COG0625	glutathione transferase activity
CDG62_14820	COG0431	NADPH-dependent FMN reductase
CDG62_14825	COG0798	PFAM Bile acid sodium symporter
CDG62_14835	COG0640	Transcriptional regulator
CDG62_14890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG62_14895	COG1530	ribonuclease E activity
CDG62_14900	COG0424	maF-like protein
CDG62_14905	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CDG62_14910	COG1792	Involved in formation and maintenance of cell shape
CDG62_14915	COG1077	Cell shape determining protein MreB Mrl
CDG62_14920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG62_14930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG62_14975	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDG62_14990	COG1595	DNA-templated transcription, initiation
CDG62_15040	COG0745	RESPONSE REGULATOR receiver
CDG62_15040	COG3706	GGDEF domain
CDG62_15055	COG1785	Belongs to the alkaline phosphatase family
CDG62_15060	COG1785	Belongs to the alkaline phosphatase family
CDG62_15065	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_15070	COG2610	gluconate transmembrane transporter activity
CDG62_15075	COG0583	DNA-binding transcription factor activity
CDG62_15085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_15095	COG4772	TonB-dependent receptor
CDG62_15100	COG4993	Dehydrogenase
CDG62_15105	COG3659	wide pore channel activity
CDG62_15110	COG3420	alginic acid biosynthetic process
CDG62_15115	COG0710	3-dehydroquinate dehydratase activity
CDG62_15120	COG3485	protocatechuate 3,4-dioxygenase
CDG62_15125	COG3485	protocatechuate 3,4-dioxygenase
CDG62_15130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDG62_15135	COG2271	Major facilitator Superfamily
CDG62_15140	COG0596	Alpha beta hydrolase
CDG62_15145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDG62_15150	COG0183	Belongs to the thiolase family
CDG62_15155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG62_15160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG62_15165	COG1414	Transcriptional regulator
CDG62_15190	COG1113	amino acid transport
CDG62_15200	COG3724	N-succinylarginine dihydrolase activity
CDG62_15205	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_15210	COG3138	arginine N-succinyltransferase
CDG62_15220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG62_15225	COG1522	sequence-specific DNA binding
CDG62_15235	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_15240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG62_15250	COG1113	amino acid transport
CDG62_15265	COG1271	oxidase subunit
CDG62_15270	COG1294	oxidase, subunit
CDG62_15280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG62_15300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG62_15310	COG1522	sequence-specific DNA binding
CDG62_15320	COG0583	DNA-binding transcription factor activity
CDG62_15325	COG2814	Major facilitator Superfamily
CDG62_15335	COG0737	Belongs to the 5'-nucleotidase family
CDG62_15350	COG3188	usher protein
CDG62_15410	COG1802	Transcriptional regulator
CDG62_15420	COG2186	Transcriptional regulator
CDG62_15430	COG1012	belongs to the aldehyde dehydrogenase family
CDG62_15440	COG2271	Major facilitator Superfamily
CDG62_15445	COG2721	sulfolactate sulfo-lyase activity
CDG62_15455	COG0745	RESPONSE REGULATOR receiver
CDG62_15460	COG2205	protein histidine kinase activity
CDG62_15465	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CDG62_15470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDG62_15475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG62_15480	COG1968	undecaprenyl-diphosphatase activity
CDG62_15500	COG1215	transferase activity, transferring glycosyl groups
CDG62_15515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDG62_15540	COG3177	Filamentation induced by cAMP protein fic
CDG62_15545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG62_15575	COG0745	RESPONSE REGULATOR receiver
CDG62_15580	COG0642	Histidine kinase
CDG62_15595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDG62_15620	COG2816	NAD+ diphosphatase activity
CDG62_15625	COG3046	protein related to deoxyribodipyrimidine photolyase
CDG62_15640	COG2351	hydroxyisourate hydrolase activity
CDG62_15660	COG2826	transposase and inactivated derivatives, IS30 family
CDG62_15670	COG2203	Gaf domain
CDG62_15670	COG2199	diguanylate cyclase activity
CDG62_15690	COG3328	transposase activity
CDG62_15725	COG0582	viral genome integration into host DNA
CDG62_15735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG62_15740	COG2814	Major facilitator Superfamily
CDG62_15745	COG1566	PFAM secretion protein HlyD family protein
CDG62_15750	COG2050	protein possibly involved in aromatic compounds catabolism
CDG62_15765	COG1090	epimerase
CDG62_15775	COG3706	GGDEF domain
CDG62_15775	COG4251	negative regulation of phosphorylation
CDG62_15775	COG2203	Gaf domain
CDG62_15775	COG5001	Diguanylate cyclase
CDG62_15780	COG0420	3'-5' exonuclease activity
CDG62_15810	COG0735	belongs to the Fur family
CDG62_15815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG62_15820	COG2914	Belongs to the UPF0125 (RnfH) family
CDG62_15835	COG0121	glutamine amidotransferase
CDG62_15850	COG0756	dUTP diphosphatase activity
CDG62_15855	COG0210	DNA helicase
CDG62_15860	COG2885	chlorophyll binding
CDG62_15865	COG0204	Acyl-transferase
CDG62_15875	COG0850	regulation of cytokinetic process
CDG62_15880	COG2894	cell division
CDG62_15885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDG62_15900	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDG62_15900	COG1674	ftsk spoiiie
CDG62_15905	COG0492	ferredoxin-NADP+ reductase activity
CDG62_15910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG62_15920	COG0456	acetyltransferase
CDG62_15960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDG62_15985	COG1113	amino acid transport
CDG62_15990	COG0251	oxidation-reduction process
CDG62_16000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG62_16005	COG1522	sequence-specific DNA binding
CDG62_16030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG62_16035	COG2076	Multidrug Resistance protein
CDG62_16040	COG2076	Multidrug Resistance protein
CDG62_16055	COG2132	Multicopper oxidase
CDG62_16065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDG62_16080	COG4269	membrane
CDG62_16100	COG1968	undecaprenyl-diphosphatase activity
CDG62_16105	COG1214	PFAM Peptidase M22, glycoprotease
CDG62_16110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG62_16115	COG0494	nUDIX hydrolase
CDG62_16165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG62_16175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG62_16215	COG2814	Major facilitator Superfamily
CDG62_16250	COG2853	Lipoprotein
CDG62_16255	COG2208	phosphoserine phosphatase activity
CDG62_16265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG62_16270	COG1764	response to oxidative stress
CDG62_16300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG62_16300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG62_16315	COG0037	tRNA processing
CDG62_16350	COG0072	phenylalanine-tRNA ligase activity
CDG62_16375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDG62_16395	COG1238	metal cluster binding
CDG62_16405	COG0625	glutathione transferase activity
CDG62_16425	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_16430	COG3028	Belongs to the UPF0307 family
CDG62_16440	COG1660	Displays ATPase and GTPase activities
CDG62_16445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDG62_16455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDG62_16460	COG0617	tRNA 3'-terminal CCA addition
CDG62_16465	COG1555	photosystem II stabilization
CDG62_16470	COG3956	TIGRFAM MazG family protein
CDG62_16480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG62_16495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG62_16500	COG5002	protein histidine kinase activity
CDG62_16500	COG0784	Response regulator, receiver
CDG62_16500	COG2205	protein histidine kinase activity
CDG62_16505	COG1024	Enoyl-CoA hydratase
CDG62_16510	COG2084	Dehydrogenase
CDG62_16515	COG3622	Belongs to the hyi family
CDG62_16530	COG0004	ammonium transporteR
CDG62_16535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CDG62_16540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDG62_16545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDG62_16550	COG2814	Major facilitator Superfamily
CDG62_16560	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_16615	COG0210	DNA helicase
CDG62_16620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG62_16675	COG3328	transposase activity
CDG62_16695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG62_16700	COG0671	phosphoesterase, PA-phosphatase related
CDG62_16705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDG62_16720	COG0084	hydrolase, TatD family'
CDG62_16735	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG62_16750	COG0793	Belongs to the peptidase S41A family
CDG62_16775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDG62_16780	COG0857	belongs to the CobB CobQ family
CDG62_16780	COG0280	phosphate acetyltransferase
CDG62_16795	COG3328	transposase activity
CDG62_16805	COG2318	DinB family
CDG62_16810	COG0697	spore germination
CDG62_16815	COG2207	Transcriptional regulator
CDG62_16815	COG1917	Cupin 2, conserved barrel domain protein
CDG62_16825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG62_16825	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG62_16845	COG0740	serine-type endopeptidase activity
CDG62_16855	COG4771	TonB-dependent receptor
CDG62_16860	COG4774	siderophore transport
CDG62_16870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG62_16880	COG2813	Specifically methylates the guanine in position
CDG62_16880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG62_16985	COG0788	formyltetrahydrofolate deformylase activity
CDG62_17000	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDG62_17005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDG62_17010	COG4651	solute:proton antiporter activity
CDG62_17010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG62_17040	COG1929	Belongs to the glycerate kinase type-1 family
CDG62_17075	COG2900	Belongs to the SlyX family
CDG62_17090	COG1560	Kdo2-lipid A biosynthetic process
CDG62_17135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDG62_17150	COG0473	3-isopropylmalate dehydrogenase activity
CDG62_17165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG62_17175	COG0583	DNA-binding transcription factor activity
CDG62_17210	COG1280	lysine exporter protein (LysE YggA)
CDG62_17225	COG1960	acyl-CoA dehydrogenase activity
CDG62_17245	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CDG62_17260	COG0583	DNA-binding transcription factor activity
CDG62_17275	COG0564	pseudouridine synthase activity
CDG62_17285	COG1530	ribonuclease E activity
CDG62_17290	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_17315	COG1983	PspC domain protein
CDG62_17340	COG0751	glycine-tRNA ligase activity
CDG62_17370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDG62_17385	COG2226	methyltransferase
CDG62_17410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDG62_17415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG62_17420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDG62_17430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG62_17440	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CDG62_17440	COG0644	oxidoreductase
CDG62_17450	COG0425	Belongs to the sulfur carrier protein TusA family
CDG62_17455	COG4535	Mg2 and Co2 transporter CorC
CDG62_17460	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDG62_17465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG62_17485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDG62_17495	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDG62_17515	COG2841	Protein conserved in bacteria
CDG62_17520	COG0598	Magnesium transport protein CorA
CDG62_17525	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG62_17540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG62_17545	COG1074	ATP-dependent DNA helicase activity
CDG62_17550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDG62_17580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG62_17600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG62_17610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG62_17615	COG2111	Na H antiporter
CDG62_17615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG62_17620	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG62_17625	COG0651	ATP synthesis coupled electron transport
CDG62_17635	COG2212	antiporter activity
CDG62_17645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG62_17655	COG0195	Participates in both transcription termination and antitermination
CDG62_17715	COG0237	dephospho-CoA kinase activity
CDG62_17725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG62_17730	COG3123	guanosine phosphorylase activity
CDG62_17735	COG0497	DNA recombination
CDG62_17740	COG1678	Uncharacterized ACR, COG1678
CDG62_17745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDG62_17750	COG1566	PFAM secretion protein HlyD family protein
CDG62_17760	COG1289	transmembrane transporter activity
CDG62_17775	COG1132	(ABC) transporter
CDG62_17780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDG62_17860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG62_17885	COG0326	Molecular chaperone. Has ATPase activity
CDG62_17895	COG3047	cAMP biosynthetic process
CDG62_17900	COG2056	Na+-H+ antiporter family
CDG62_17925	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDG62_17935	COG0085	RNA polymerase activity
CDG62_17940	COG0222	ribosome binding
CDG62_17945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDG62_17950	COG0081	regulation of translation
CDG62_17955	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDG62_18005	COG0546	phosphoglycolate phosphatase activity
CDG62_18035	COG0824	Thioesterase
CDG62_18055	COG0181	hydroxymethylbilane synthase activity
CDG62_18065	COG3275	phosphorelay sensor kinase activity
CDG62_18085	COG1538	Outer membrane efflux protein
CDG62_18095	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDG62_18105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDG62_18110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDG62_18115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG62_18120	COG0772	Belongs to the SEDS family
CDG62_18125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDG62_18145	COG4974	Belongs to the 'phage' integrase family
CDG62_18150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG62_18165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG62_18175	COG2197	response regulator
CDG62_18190	COG0793	Belongs to the peptidase S41A family
CDG62_18195	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDG62_18200	COG0795	lipopolysaccharide-transporting ATPase activity
CDG62_18205	COG0795	lipopolysaccharide-transporting ATPase activity
CDG62_18225	COG0586	Pfam SNARE associated Golgi protein
CDG62_18240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG62_18240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG62_18250	COG0004	ammonium transporteR
CDG62_18255	COG0347	Belongs to the P(II) protein family
CDG62_18265	COG0606	chelatase, subunit chli
CDG62_18285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG62_18300	COG0318	PFAM AMP-dependent synthetase and ligase
CDG62_18310	COG0477	Major facilitator Superfamily
CDG62_18315	COG2860	membrane
CDG62_18320	COG3012	SEC-C Motif Domain Protein
CDG62_18325	COG1253	flavin adenine dinucleotide binding
CDG62_18355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG62_18430	COG0758	DNA mediated transformation
CDG62_18440	COG0697	spore germination
CDG62_18450	COG0386	Belongs to the glutathione peroxidase family
CDG62_18485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG62_18495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDG62_18535	COG1121	(ABC) transporter
CDG62_18540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG62_18555	COG2837	iron assimilation
CDG62_18585	COG3501	Rhs element vgr protein
CDG62_18590	COG0281	malic enzyme
CDG62_18615	COG2267	carboxylic ester hydrolase activity
CDG62_18640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG62_18640	COG0519	Catalyzes the synthesis of GMP from XMP
CDG62_18650	COG2259	Doxx family
CDG62_18655	COG0586	Pfam SNARE associated Golgi protein
CDG62_18670	COG1192	Involved in chromosome partitioning
CDG62_18680	COG0271	Belongs to the BolA IbaG family
CDG62_18710	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_18750	COG2986	histidine ammonia-lyase
CDG62_18765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG62_18775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG62_18795	COG0583	DNA-binding transcription factor activity
CDG62_18800	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDG62_18815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDG62_18825	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDG62_18830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDG62_18840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG62_18845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG62_18850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG62_18865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG62_18875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG62_18885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG62_18915	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG62_18925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDG62_18955	COG0728	peptidoglycan biosynthetic process
CDG62_18960	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDG62_18970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG62_18980	COG3307	-O-antigen
CDG62_18990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG62_18995	COG0546	phosphoglycolate phosphatase activity
CDG62_19000	COG1028	Short-chain dehydrogenase reductase Sdr
CDG62_19020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG62_19020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG62_19025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_19030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG62_19035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG62_19040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG62_19045	COG1116	anion transmembrane transporter activity
CDG62_19050	COG1309	transcriptional regulator
CDG62_19065	COG0196	riboflavin kinase activity
CDG62_19070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG62_19075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDG62_19080	COG1047	Peptidyl-prolyl cis-trans
CDG62_19100	COG2133	pyrroloquinoline quinone binding
CDG62_19130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG62_19135	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG62_19140	COG2951	lytic endotransglycosylase activity
CDG62_19145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDG62_19160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG62_19180	COG0861	Integral membrane protein TerC family
CDG62_19190	COG0754	glutathionylspermidine amidase activity
CDG62_19200	COG0402	S-adenosylhomocysteine deaminase activity
CDG62_19215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG62_19220	COG1230	cation diffusion facilitator family transporter
CDG62_19240	COG0706	membrane insertase activity
CDG62_19245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDG62_19255	COG0230	Belongs to the bacterial ribosomal protein bL34 family