locus-tag	class	description
CDG60_00020	COG3173	Aminoglycoside phosphotransferase
CDG60_00030	COG2801	Transposase and inactivated derivatives
CDG60_00190	COG0739	heme binding
CDG60_00190	COG0741	lytic transglycosylase activity
CDG60_00190	COG1196	nuclear chromosome segregation
CDG60_00250	COG1192	Involved in chromosome partitioning
CDG60_00310	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_00330	COG0673	inositol 2-dehydrogenase activity
CDG60_00335	COG1324	tolerance protein
CDG60_00365	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_00385	COG1525	nuclease
CDG60_00410	COG1196	nuclear chromosome segregation
CDG60_00410	COG0741	lytic transglycosylase activity
CDG60_00410	COG0739	heme binding
CDG60_00435	COG1475	DNA binding
CDG60_00440	COG1192	Involved in chromosome partitioning
CDG60_00475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG60_00490	COG1570	exodeoxyribonuclease VII activity
CDG60_00495	COG3316	Transposase and inactivated derivatives
CDG60_00510	COG3657	addiction module killer protein
CDG60_00515	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG60_00525	COG2801	Transposase and inactivated derivatives
CDG60_00545	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_00555	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_00605	COG2801	Transposase and inactivated derivatives
CDG60_00615	COG0745	RESPONSE REGULATOR receiver
CDG60_00620	COG5002	protein histidine kinase activity
CDG60_00630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG60_00650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDG60_00725	COG1660	Displays ATPase and GTPase activities
CDG60_00745	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG60_00750	COG0592	DNA-directed DNA polymerase activity
CDG60_00760	COG0187	DNA topoisomerase II activity
CDG60_00770	COG0488	(ABC) transporter
CDG60_00795	COG0316	Belongs to the HesB IscA family
CDG60_00805	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG60_00810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG60_00815	COG4521	taurine ABC transporter
CDG60_00820	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CDG60_00825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG60_00830	COG2175	clavaminate synthase activity
CDG60_00840	COG0737	Belongs to the 5'-nucleotidase family
CDG60_00875	COG2814	Major facilitator Superfamily
CDG60_00900	COG1047	Peptidyl-prolyl cis-trans
CDG60_00905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDG60_00910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG60_00915	COG0196	riboflavin kinase activity
CDG60_00930	COG1309	transcriptional regulator
CDG60_00935	COG1116	anion transmembrane transporter activity
CDG60_00940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG60_00945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG60_00950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG60_00955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG60_00960	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG60_00960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG60_00980	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_00985	COG0546	phosphoglycolate phosphatase activity
CDG60_00990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDG60_01005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG60_01005	COG1017	nitric oxide dioxygenase activity
CDG60_01015	COG1309	transcriptional regulator
CDG60_01065	COG1596	polysaccharide export
CDG60_01070	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDG60_01115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG60_01125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG60_01135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG60_01150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG60_01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG60_01200	COG0768	penicillin binding
CDG60_01205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDG60_01210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDG60_01220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG60_01230	COG0735	belongs to the Fur family
CDG60_01235	COG0215	cysteine-tRNA ligase activity
CDG60_01250	COG0523	cobalamin synthesis protein
CDG60_01255	COG0640	Transcriptional regulator
CDG60_01280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDG60_01310	COG1294	oxidase, subunit
CDG60_01315	COG1271	oxidase subunit
CDG60_01340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG60_01350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDG60_01380	COG0271	Belongs to the BolA IbaG family
CDG60_01390	COG1192	Involved in chromosome partitioning
CDG60_01405	COG0586	Pfam SNARE associated Golgi protein
CDG60_01410	COG2259	Doxx family
CDG60_01415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG60_01415	COG0519	Catalyzes the synthesis of GMP from XMP
CDG60_01420	COG1715	Restriction endonuclease
CDG60_01455	COG2267	carboxylic ester hydrolase activity
CDG60_01465	COG0697	spore germination
CDG60_01480	COG0281	malic enzyme
CDG60_01485	COG3501	Rhs element vgr protein
CDG60_01500	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_01515	COG2837	iron assimilation
CDG60_01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG60_01535	COG1121	(ABC) transporter
CDG60_01575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDG60_01585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG60_01620	COG2072	flavoprotein involved in K transport
CDG60_01625	COG4221	oxidoreductase activity
CDG60_01640	COG0386	Belongs to the glutathione peroxidase family
CDG60_01655	COG1309	transcriptional regulator
CDG60_01660	COG0697	spore germination
CDG60_01670	COG0758	DNA mediated transformation
CDG60_01705	COG1309	transcriptional regulator
CDG60_01760	COG2814	Major facilitator Superfamily
CDG60_01800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG60_01805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDG60_01835	COG1253	flavin adenine dinucleotide binding
CDG60_01860	COG2860	membrane
CDG60_01865	COG0477	Major facilitator Superfamily
CDG60_01885	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_01900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG60_01925	COG0606	chelatase, subunit chli
CDG60_01935	COG0347	Belongs to the P(II) protein family
CDG60_01940	COG0004	ammonium transporteR
CDG60_01950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG60_01950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG60_01965	COG0586	Pfam SNARE associated Golgi protein
CDG60_01990	COG0795	lipopolysaccharide-transporting ATPase activity
CDG60_01995	COG0795	lipopolysaccharide-transporting ATPase activity
CDG60_02000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDG60_02005	COG0793	Belongs to the peptidase S41A family
CDG60_02020	COG2197	response regulator
CDG60_02025	COG1686	Belongs to the peptidase S11 family
CDG60_02030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG60_02040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG60_02045	COG4974	Belongs to the 'phage' integrase family
CDG60_02070	COG0772	Belongs to the SEDS family
CDG60_02080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG60_02085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDG60_02090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDG60_02095	COG0494	nUDIX hydrolase
CDG60_02100	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDG60_02110	COG1538	Outer membrane efflux protein
CDG60_02130	COG3275	phosphorelay sensor kinase activity
CDG60_02140	COG0181	hydroxymethylbilane synthase activity
CDG60_02230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDG60_02245	COG0081	regulation of translation
CDG60_02250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDG60_02260	COG0085	RNA polymerase activity
CDG60_02285	COG2056	Na+-H+ antiporter family
CDG60_02305	COG0326	Molecular chaperone. Has ATPase activity
CDG60_02330	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG60_02355	COG0183	Belongs to the thiolase family
CDG60_02410	COG1132	(ABC) transporter
CDG60_02420	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG60_02430	COG1289	transmembrane transporter activity
CDG60_02450	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDG60_02460	COG0497	DNA recombination
CDG60_02470	COG3123	guanosine phosphorylase activity
CDG60_02475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG60_02485	COG0237	dephospho-CoA kinase activity
CDG60_02540	COG0195	Participates in both transcription termination and antitermination
CDG60_02550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG60_02560	COG2212	antiporter activity
CDG60_02570	COG0651	ATP synthesis coupled electron transport
CDG60_02575	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG60_02580	COG2111	Na H antiporter
CDG60_02580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG60_02595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG60_02620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG60_02650	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDG60_02655	COG1074	ATP-dependent DNA helicase activity
CDG60_02660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG60_02675	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG60_02680	COG0598	Magnesium transport protein CorA
CDG60_02715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDG60_02725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDG60_02755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDG60_02760	COG4535	Mg2 and Co2 transporter CorC
CDG60_02770	COG0644	oxidoreductase
CDG60_02770	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CDG60_02780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG60_02795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG60_02800	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDG60_02810	COG0493	'glutamate synthase
CDG60_02850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDG60_02900	COG1983	PspC domain protein
CDG60_02935	COG1530	ribonuclease E activity
CDG60_02945	COG0564	pseudouridine synthase activity
CDG60_02950	COG0546	phosphoglycolate phosphatase activity
CDG60_02955	COG3971	2-oxopent-4-enoate hydratase activity
CDG60_02960	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CDG60_02985	COG0583	DNA-binding transcription factor activity
CDG60_02990	COG4638	Rieske (2fe-2S)
CDG60_03005	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_03010	COG3384	dioxygenase
CDG60_03015	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG60_03040	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CDG60_03075	COG2801	Transposase and inactivated derivatives
CDG60_03085	COG1960	acyl-CoA dehydrogenase activity
CDG60_03125	COG0583	DNA-binding transcription factor activity
CDG60_03145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDG60_03160	COG0473	3-isopropylmalate dehydrogenase activity
CDG60_03180	COG0101	tRNA pseudouridine synthase activity
CDG60_03220	COG1560	Kdo2-lipid A biosynthetic process
CDG60_03240	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_03245	COG1733	regulation of RNA biosynthetic process
CDG60_03260	COG2816	NAD+ diphosphatase activity
CDG60_03280	COG1929	Belongs to the glycerate kinase type-1 family
CDG60_03285	COG0210	DNA helicase
CDG60_03290	COG0724	RNA recognition motif
CDG60_03310	COG4651	solute:proton antiporter activity
CDG60_03310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG60_03315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDG60_03320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDG60_03335	COG0788	formyltetrahydrofolate deformylase activity
CDG60_03365	COG1295	ribonuclease BN
CDG60_03395	COG0793	Belongs to the peptidase S41A family
CDG60_03405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG60_03420	COG0084	hydrolase, TatD family'
CDG60_03435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDG60_03440	COG4589	Belongs to the CDS family
CDG60_03460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG60_03575	COG0556	nucleotide-excision repair
CDG60_03595	COG2814	Major facilitator Superfamily
CDG60_03620	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDG60_03625	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDG60_03630	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CDG60_03640	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_03655	COG0004	ammonium transporteR
CDG60_03665	COG3622	Belongs to the hyi family
CDG60_03670	COG2084	Dehydrogenase
CDG60_03675	COG1024	Enoyl-CoA hydratase
CDG60_03680	COG5002	protein histidine kinase activity
CDG60_03680	COG2205	protein histidine kinase activity
CDG60_03680	COG0784	Response regulator, receiver
CDG60_03700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG60_03720	COG1862	Preprotein translocase
CDG60_03730	COG1704	LemA family
CDG60_03740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDG60_03750	COG0784	Response regulator, receiver
CDG60_03750	COG2205	protein histidine kinase activity
CDG60_03755	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG60_03780	COG0438	transferase activity, transferring glycosyl groups
CDG60_03805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDG60_03830	COG1216	Glycosyl transferase, family 2
CDG60_03830	COG0463	Glycosyl transferase, family 2
CDG60_03850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG60_03900	COG1960	acyl-CoA dehydrogenase activity
CDG60_03905	COG1960	acyl-CoA dehydrogenase activity
CDG60_03920	COG2205	protein histidine kinase activity
CDG60_03925	COG0745	RESPONSE REGULATOR receiver
CDG60_03930	COG2315	Protein conserved in bacteria
CDG60_03970	COG2096	Adenosyltransferase
CDG60_03975	COG4206	TonB-dependent receptor
CDG60_03990	COG0133	tryptophan synthase activity
CDG60_04005	COG3083	sulfuric ester hydrolase activity
CDG60_04035	COG0285	dihydrofolate synthase activity
CDG60_04055	COG0450	alkyl hydroperoxide reductase
CDG60_04070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG60_04075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG60_04105	COG2199	diguanylate cyclase activity
CDG60_04170	COG2969	positive regulation of protein catabolic process
CDG60_04175	COG0625	glutathione transferase activity
CDG60_04180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG60_04185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG60_04190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDG60_04195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG60_04200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG60_04230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG60_04240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG60_04245	COG1408	metallophosphoesterase
CDG60_04255	COG0477	Major facilitator Superfamily
CDG60_04260	COG1272	protein, Hemolysin III
CDG60_04275	COG1011	Hydrolase
CDG60_04290	COG1522	sequence-specific DNA binding
CDG60_04295	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDG60_04295	COG1024	Enoyl-CoA hydratase
CDG60_04300	COG0183	Belongs to the thiolase family
CDG60_04305	COG2207	Transcriptional regulator
CDG60_04310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG60_04325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG60_04355	COG0183	Belongs to the thiolase family
CDG60_04365	COG2885	chlorophyll binding
CDG60_04365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CDG60_04375	COG0494	nUDIX hydrolase
CDG60_04385	COG1214	PFAM Peptidase M22, glycoprotease
CDG60_04390	COG1968	undecaprenyl-diphosphatase activity
CDG60_04410	COG4269	membrane
CDG60_04420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDG60_04430	COG2132	Multicopper oxidase
CDG60_04445	COG2076	Multidrug Resistance protein
CDG60_04450	COG2076	Multidrug Resistance protein
CDG60_04455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDG60_04470	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_04470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG60_04470	COG0351	phosphomethylpyrimidine kinase
CDG60_04495	COG0251	oxidation-reduction process
CDG60_04500	COG1113	amino acid transport
CDG60_04510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG60_04535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDG60_04560	COG0456	acetyltransferase
CDG60_04570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG60_04575	COG0492	ferredoxin-NADP+ reductase activity
CDG60_04580	COG1674	ftsk spoiiie
CDG60_04580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDG60_04595	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDG60_04600	COG2894	cell division
CDG60_04615	COG0204	Acyl-transferase
CDG60_04620	COG2885	chlorophyll binding
CDG60_04625	COG0210	DNA helicase
CDG60_04630	COG0756	dUTP diphosphatase activity
CDG60_04635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG60_04640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG60_04650	COG0121	glutamine amidotransferase
CDG60_04670	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG60_04675	COG0735	belongs to the Fur family
CDG60_04715	COG0420	3'-5' exonuclease activity
CDG60_04750	COG0564	pseudouridine synthase activity
CDG60_04755	COG0456	acetyltransferase
CDG60_04770	COG3189	MarR family transcriptional regulator
CDG60_04775	COG2824	Alkylphosphonate utilization operon protein PhnA
CDG60_04785	COG3422	double-strand break repair
CDG60_04810	COG5342	invasion associated locus B
CDG60_04830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDG60_04855	COG0730	response to heat
CDG60_04865	COG1196	nuclear chromosome segregation
CDG60_04875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG60_04900	COG2193	ferroxidase activity
CDG60_04905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG60_04910	COG2267	carboxylic ester hydrolase activity
CDG60_04925	COG4106	trans-aconitate 2-methyltransferase activity
CDG60_04950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG60_04955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG60_04970	COG0009	L-threonylcarbamoyladenylate synthase
CDG60_04975	COG3101	peptidyl-lysine hydroxylation
CDG60_04980	COG1399	metal-binding, possibly nucleic acid-binding protein
CDG60_04995	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_05005	COG1652	LysM domain
CDG60_05065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG60_05080	COG0745	RESPONSE REGULATOR receiver
CDG60_05085	COG2205	protein histidine kinase activity
CDG60_05090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG60_05105	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG60_05130	COG0745	RESPONSE REGULATOR receiver
CDG60_05150	COG0004	ammonium transporteR
CDG60_05160	COG1126	abc transporter atp-binding protein
CDG60_05165	COG0765	amino acid transport
CDG60_05170	COG0765	amino acid transport
CDG60_05185	COG2852	Protein conserved in bacteria
CDG60_05210	COG0525	valine-tRNA ligase activity
CDG60_05220	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_05235	COG0393	Putative heavy-metal-binding
CDG60_05240	COG1538	Outer membrane efflux protein
CDG60_05250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG60_05255	COG0671	phosphoesterase, PA-phosphatase related
CDG60_05270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDG60_05280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDG60_05295	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDG60_05300	COG1648	precorrin-2 dehydrogenase activity
CDG60_05300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG60_05305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG60_05315	COG0531	amino acid
CDG60_05335	COG0321	lipoyl(octanoyl) transferase activity
CDG60_05340	COG2921	Belongs to the UPF0250 family
CDG60_05345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDG60_05365	COG0586	Pfam SNARE associated Golgi protein
CDG60_05385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG60_05415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDG60_05445	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDG60_05460	COG0358	DNA primase activity
CDG60_05470	COG0564	pseudouridine synthase activity
CDG60_05505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDG60_05510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG60_05545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG60_05545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG60_05580	COG2009	succinate dehydrogenase
CDG60_05585	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDG60_05590	COG1053	succinate dehydrogenase
CDG60_05595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG60_05610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG60_05620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDG60_05625	COG2268	Band 7 protein
CDG60_05630	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG60_05640	COG2354	Protein conserved in bacteria
CDG60_05645	COG2321	neutral zinc metallopeptidase
CDG60_05700	COG0457	Tetratricopeptide repeat
CDG60_05725	COG0110	maltose O-acetyltransferase activity
CDG60_05730	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDG60_05740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDG60_05745	COG0505	Belongs to the CarA family
CDG60_05765	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDG60_05770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG60_05775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG60_05820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDG60_05835	COG0477	Major facilitator Superfamily
CDG60_05850	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CDG60_05870	COG0459	protein refolding
CDG60_05875	COG5295	Hep Hag repeat protein
CDG60_05890	COG0584	glycerophosphoryl diester phosphodiesterase
CDG60_05895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG60_05900	COG2239	Acts as a magnesium transporter
CDG60_05915	COG0501	Belongs to the peptidase M48B family
CDG60_05920	COG0739	heme binding
CDG60_05920	COG0741	lytic transglycosylase activity
CDG60_05920	COG1196	nuclear chromosome segregation
CDG60_05925	COG0037	tRNA processing
CDG60_05940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG60_05975	COG0006	proline dipeptidase activity
CDG60_05985	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CDG60_06000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG60_06005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG60_06045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG60_06050	COG1388	LysM domain
CDG60_06050	COG0741	lytic transglycosylase activity
CDG60_06060	COG4174	ABC transporter (Permease)
CDG60_06065	COG4239	(ABC) transporter, permease
CDG60_06070	COG4172	Belongs to the ABC transporter superfamily
CDG60_06095	COG0281	malic enzyme
CDG60_06095	COG0280	phosphate acetyltransferase
CDG60_06100	COG5001	Diguanylate cyclase
CDG60_06100	COG3300	MHYT domain
CDG60_06105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG60_06115	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG60_06155	COG0582	viral genome integration into host DNA
CDG60_06210	COG0833	amino acid
CDG60_06220	COG0833	amino acid
CDG60_06225	COG4771	TonB-dependent receptor
CDG60_06235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG60_06240	COG0418	dihydroorotase activity
CDG60_06245	COG3706	GGDEF domain
CDG60_06250	COG3706	GGDEF domain
CDG60_06250	COG2203	Gaf domain
CDG60_06250	COG4251	negative regulation of phosphorylation
CDG60_06250	COG5001	Diguanylate cyclase
CDG60_06260	COG0583	DNA-binding transcription factor activity
CDG60_06265	COG0697	spore germination
CDG60_06280	COG2186	Transcriptional regulator
CDG60_06290	COG0277	FAD linked oxidase domain protein
CDG60_06300	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG60_06300	COG1902	pentaerythritol trinitrate reductase activity
CDG60_06335	COG1629	transport
CDG60_06335	COG4206	TonB-dependent receptor
CDG60_06350	COG1785	Belongs to the alkaline phosphatase family
CDG60_06355	COG1785	Belongs to the alkaline phosphatase family
CDG60_06370	COG3706	GGDEF domain
CDG60_06370	COG0745	RESPONSE REGULATOR receiver
CDG60_06430	COG0235	Class ii aldolase
CDG60_06445	COG1115	amino acid carrier protein
CDG60_06450	COG1113	amino acid transport
CDG60_06460	COG0019	diaminopimelate decarboxylase activity
CDG60_06465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDG60_06470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CDG60_06520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG60_06540	COG1671	Belongs to the UPF0178 family
CDG60_06555	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDG60_06560	COG1136	(ABC) transporter
CDG60_06565	COG2333	competence protein COMEC
CDG60_06565	COG0658	competence protein
CDG60_06585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDG60_06590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDG60_06595	COG0628	permease
CDG60_06630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG60_06650	COG0823	Involved in the tonB-independent uptake of proteins
CDG60_06670	COG0824	Thioesterase
CDG60_06680	COG0583	DNA-binding transcription factor activity
CDG60_06685	COG0473	3-isopropylmalate dehydrogenase activity
CDG60_06720	COG1454	alcohol dehydrogenase
CDG60_06730	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_06740	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG60_06740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG60_06755	COG0583	DNA-binding transcription factor activity
CDG60_06770	COG1024	Enoyl-CoA hydratase
CDG60_06775	COG1051	belongs to the nudix hydrolase family
CDG60_06775	COG1056	cytidyltransferase-related domain
CDG60_06790	COG0583	DNA-binding transcription factor activity
CDG60_06800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG60_06810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDG60_06815	COG0602	queuosine metabolic process
CDG60_06835	COG0583	DNA-binding transcription factor activity
CDG60_06840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDG60_06845	COG4208	sulfate ABC transporter
CDG60_06860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG60_06865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDG60_06870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDG60_06885	COG2207	Transcriptional regulator
CDG60_06910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG60_06925	COG0681	Belongs to the peptidase S26 family
CDG60_06935	COG0571	ribonuclease III activity
CDG60_06940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG60_06950	COG1381	Involved in DNA repair and RecF pathway recombination
CDG60_06955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDG60_07010	COG3706	GGDEF domain
CDG60_07010	COG0745	RESPONSE REGULATOR receiver
CDG60_07020	COG0556	nucleotide-excision repair
CDG60_07055	COG1733	regulation of RNA biosynthetic process
CDG60_07065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDG60_07075	COG0671	phosphoesterase, PA-phosphatase related
CDG60_07085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG60_07090	COG0076	glutamate decarboxylase activity
CDG60_07105	COG0573	inorganic phosphate transmembrane transporter activity
CDG60_07115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG60_07125	COG0616	signal peptide processing
CDG60_07150	COG2915	High frequency lysogenization protein hflD homolog
CDG60_07155	COG0482	sulfurtransferase activity
CDG60_07165	COG2819	hydrolase of the alpha beta superfamily
CDG60_07180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG60_07185	COG1686	Belongs to the peptidase S11 family
CDG60_07210	COG0583	DNA-binding transcription factor activity
CDG60_07215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG60_07220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG60_07225	COG1067	ATP-dependent peptidase activity
CDG60_07230	COG2211	Major facilitator Superfamily
CDG60_07260	COG1509	lysine 2,3-aminomutase activity
CDG60_07265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG60_07270	COG1966	Carbon starvation protein
CDG60_07275	COG2879	small protein
CDG60_07280	COG0714	Associated with various cellular activities
CDG60_07310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDG60_07315	COG1845	cytochrome c oxidase, subunit III
CDG60_07320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG60_07325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG60_07340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDG60_07355	COG4682	membrane
CDG60_07360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG60_07380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDG60_07385	COG2890	protein-(glutamine-N5) methyltransferase activity
CDG60_07405	COG1960	acyl-CoA dehydrogenase activity
CDG60_07410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG60_07425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDG60_07430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG60_07450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG60_07455	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDG60_07465	COG2205	protein histidine kinase activity
CDG60_07470	COG0745	RESPONSE REGULATOR receiver
CDG60_07480	COG0477	Major facilitator Superfamily
CDG60_07485	COG0729	surface antigen
CDG60_07515	COG0288	reversible hydration of carbon dioxide
CDG60_07595	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG60_07610	COG1113	amino acid transport
CDG60_07635	COG0308	aminopeptidase N
CDG60_07645	COG0589	response to stress
CDG60_07650	COG0589	response to stress
CDG60_07665	COG3135	benzoate transporter
CDG60_07675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDG60_07680	COG0583	DNA-binding transcription factor activity
CDG60_07700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG60_07705	COG3850	Histidine kinase
CDG60_07710	COG0659	secondary active sulfate transmembrane transporter activity
CDG60_07715	COG0625	glutathione transferase activity
CDG60_07730	COG2363	Small membrane protein
CDG60_07745	COG1278	Cold shock
CDG60_07750	COG0513	Belongs to the DEAD box helicase family
CDG60_07760	COG0778	Nitroreductase
CDG60_07815	COG4783	chaperone-mediated protein folding
CDG60_07830	COG1610	YqeY-like protein
CDG60_07835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDG60_07845	COG0307	riboflavin synthase, alpha
CDG60_07900	COG0069	glutamate synthase activity
CDG60_07910	COG4585	Histidine kinase
CDG60_07915	COG2850	peptidyl-arginine hydroxylation
CDG60_07925	COG0424	maF-like protein
CDG60_07950	COG0697	spore germination
CDG60_07965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_07975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG60_07980	COG3123	guanosine phosphorylase activity
CDG60_07985	COG0583	DNA-binding transcription factor activity
CDG60_07990	COG0667	Aldo Keto reductase
CDG60_08020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG60_08025	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG60_08025	COG0506	proline dehydrogenase activity
CDG60_08025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG60_08040	COG1027	Aspartate ammonia-lyase
CDG60_08050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDG60_08060	COG1960	acyl-CoA dehydrogenase activity
CDG60_08070	COG0583	DNA-binding transcription factor activity
CDG60_08085	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG60_08085	COG1902	pentaerythritol trinitrate reductase activity
CDG60_08100	COG2814	Major facilitator Superfamily
CDG60_08105	COG0656	L-ascorbic acid biosynthetic process
CDG60_08110	COG0583	DNA-binding transcription factor activity
CDG60_08130	COG0148	phosphopyruvate hydratase activity
CDG60_08145	COG0772	Belongs to the SEDS family
CDG60_08175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG60_08180	COG0730	response to heat
CDG60_08185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_08190	COG2207	Transcriptional regulator
CDG60_08195	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG60_08200	COG2910	NAD(P)H-binding
CDG60_08205	COG0583	DNA-binding transcription factor activity
CDG60_08215	COG1960	acyl-CoA dehydrogenase activity
CDG60_08280	COG2431	L-lysine efflux transmembrane transporter activity
CDG60_08295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDG60_08305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG60_08315	COG1253	flavin adenine dinucleotide binding
CDG60_08330	COG4890	Cyd operon protein YbgT
CDG60_08335	COG1294	oxidase, subunit
CDG60_08350	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG60_08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG60_08370	COG1051	belongs to the nudix hydrolase family
CDG60_08395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG60_08400	COG0569	domain protein
CDG60_08415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG60_08420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDG60_08440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG60_08445	COG0542	response to heat
CDG60_08490	COG0372	Belongs to the citrate synthase family
CDG60_08545	COG1396	sequence-specific DNA binding
CDG60_08600	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_08610	COG1278	Cold shock
CDG60_08660	COG1802	Transcriptional regulator
CDG60_08660	COG4626	Terminase
CDG60_08665	COG4695	Portal protein
CDG60_08805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG60_08820	COG2323	membrane
CDG60_08835	COG0582	viral genome integration into host DNA
CDG60_08840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG60_08860	COG2814	Major facilitator Superfamily
CDG60_08870	COG2199	diguanylate cyclase activity
CDG60_08880	COG0439	Biotin carboxylase
CDG60_08885	COG0511	ligase activity, forming carbon-carbon bonds
CDG60_08905	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDG60_08920	COG1346	cytolysis
CDG60_08930	COG0583	DNA-binding transcription factor activity
CDG60_08950	COG1840	ABC-type Fe3 transport system, periplasmic component
CDG60_08955	COG3842	ATPase activity
CDG60_08975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG60_08990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDG60_09000	COG0745	RESPONSE REGULATOR receiver
CDG60_09030	COG4206	TonB-dependent receptor
CDG60_09040	COG0596	Alpha beta hydrolase
CDG60_09045	COG4772	TonB-dependent receptor
CDG60_09125	COG0210	DNA helicase
CDG60_09130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDG60_09175	COG0431	NADPH-dependent FMN reductase
CDG60_09180	COG1902	pentaerythritol trinitrate reductase activity
CDG60_09200	COG1741	Belongs to the pirin family
CDG60_09210	COG1944	ATP diphosphatase activity
CDG60_09235	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_09240	COG0697	spore germination
CDG60_09250	COG0583	DNA-binding transcription factor activity
CDG60_09255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG60_09260	COG2937	Belongs to the GPAT DAPAT family
CDG60_09265	COG0640	Transcriptional regulator
CDG60_09285	COG3122	Protein conserved in bacteria
CDG60_09290	COG0668	transmembrane transport
CDG60_09295	COG1132	(ABC) transporter
CDG60_09300	COG2030	dehydratase
CDG60_09310	COG0509	glycine decarboxylation via glycine cleavage system
CDG60_09320	COG2814	Major facilitator Superfamily
CDG60_09330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG60_09335	COG1448	Aminotransferase
CDG60_09340	COG0488	(ABC) transporter
CDG60_09345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG60_09350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG60_09370	COG0697	spore germination
CDG60_09455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG60_09470	COG1294	oxidase, subunit
CDG60_09475	COG1271	oxidase subunit
CDG60_09520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG60_09560	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDG60_09730	COG5410	chromosome segregation
CDG60_09865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG60_09905	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CDG60_09915	COG0552	protein localization to endoplasmic reticulum
CDG60_09920	COG0612	Peptidase, M16
CDG60_09950	COG0517	IMP dehydrogenase activity
CDG60_09950	COG0516	GMP reductase activity
CDG60_09955	COG0133	tryptophan synthase activity
CDG60_09970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG60_09990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG60_10020	COG0537	adenosine 5'-monophosphoramidase activity
CDG60_10030	COG3753	Protein conserved in bacteria
CDG60_10045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG60_10075	COG0822	iron-sulfur transferase activity
CDG60_10080	COG0316	Belongs to the HesB IscA family
CDG60_10110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDG60_10125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG60_10130	COG0702	epimerase
CDG60_10135	COG0268	Binds directly to 16S ribosomal RNA
CDG60_10155	COG1218	3'(2'),5'-bisphosphate nucleotidase
CDG60_10160	COG1011	Hydrolase
CDG60_10165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDG60_10170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDG60_10175	COG2137	regulation of response to DNA damage stimulus
CDG60_10190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_10195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDG60_10200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG60_10210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG60_10225	COG0575	Belongs to the CDS family
CDG60_10230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG60_10250	COG3852	Histidine kinase
CDG60_10255	COG2204	response regulator
CDG60_10265	COG0583	DNA-binding transcription factor activity
CDG60_10270	COG0024	Methionine aminopeptidase
CDG60_10275	COG1114	Component of the transport system for branched-chain amino acids
CDG60_10285	COG0776	regulation of translation
CDG60_10305	COG0590	tRNA wobble adenosine to inosine editing
CDG60_10315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDG60_10350	COG0084	hydrolase, TatD family'
CDG60_10370	COG1663	tetraacyldisaccharide 4'-kinase activity
CDG60_10375	COG1132	(ABC) transporter
CDG60_10385	COG0811	peptide transport
CDG60_10390	COG1475	DNA binding
CDG60_10395	COG1192	Involved in chromosome partitioning
CDG60_10405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDG60_10410	COG3178	'Phosphotransferase
CDG60_10420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG60_10425	COG1923	regulation of RNA biosynthetic process
CDG60_10435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDG60_10440	COG0802	atpase or kinase
CDG60_10460	COG1187	pseudouridine synthase activity
CDG60_10465	COG2707	UPF0756 membrane protein
CDG60_10490	COG0583	DNA-binding transcription factor activity
CDG60_10495	COG0786	glutamate:sodium symporter activity
CDG60_10500	COG2814	Major facilitator Superfamily
CDG60_10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG60_10510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG60_10520	COG1454	alcohol dehydrogenase
CDG60_10550	COG0583	DNA-binding transcription factor activity
CDG60_10570	COG1309	transcriptional regulator
CDG60_10575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG60_10575	COG0519	Catalyzes the synthesis of GMP from XMP
CDG60_10580	COG2353	YceI-like domain
CDG60_10600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDG60_10605	COG3706	GGDEF domain
CDG60_10610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG60_10655	COG1254	Belongs to the acylphosphatase family
CDG60_10660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDG60_10660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDG60_10665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDG60_10685	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_10700	COG1278	Cold shock
CDG60_10710	COG0204	Acyl-transferase
CDG60_10730	COG0012	GTP binding
CDG60_10750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDG60_10765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CDG60_10780	COG0386	Belongs to the glutathione peroxidase family
CDG60_10785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG60_10790	COG0436	Aminotransferase
CDG60_10815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG60_10820	COG1454	alcohol dehydrogenase
CDG60_10825	COG0824	Thioesterase
CDG60_10835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDG60_10850	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_10855	COG0183	Belongs to the thiolase family
CDG60_10880	COG2885	chlorophyll binding
CDG60_10890	COG0540	Belongs to the ATCase OTCase family
CDG60_10920	COG0542	response to heat
CDG60_10925	COG1045	serine acetyltransferase
CDG60_10935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG60_10940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDG60_10945	COG1765	OsmC-like protein
CDG60_10960	COG0667	Aldo Keto reductase
CDG60_10975	COG4783	chaperone-mediated protein folding
CDG60_10980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG60_11010	COG3008	intermembrane lipid transfer
CDG60_11010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG60_11015	COG2995	paraquat-inducible protein a
CDG60_11020	COG2995	paraquat-inducible protein a
CDG60_11030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDG60_11050	COG0527	aspartate kinase activity
CDG60_11060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG60_11070	COG3038	cytochrome b561
CDG60_11080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG60_11085	COG2252	PERMEase
CDG60_11095	COG0360	Binds together with S18 to 16S ribosomal RNA
CDG60_11100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDG60_11110	COG0305	Participates in initiation and elongation during chromosome replication
CDG60_11135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG60_11145	COG1305	Transglutaminase-like
CDG60_11155	COG2308	Evidence 4 Homologs of previously reported genes of
CDG60_11165	COG2814	Major facilitator Superfamily
CDG60_11205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG60_11210	COG0138	bifunctional purine biosynthesis protein purh
CDG60_11215	COG0151	Belongs to the GarS family
CDG60_11235	COG1464	Belongs to the NlpA lipoprotein family
CDG60_11240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG60_11245	COG2011	ABC-type metal ion transport system permease component
CDG60_11285	COG2203	Gaf domain
CDG60_11285	COG2199	diguanylate cyclase activity
CDG60_11300	COG4638	Rieske (2fe-2S)
CDG60_11305	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDG60_11310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG60_11310	COG0543	2 iron, 2 sulfur cluster binding
CDG60_11330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_11340	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_11355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDG60_11365	COG4122	O-methyltransferase activity
CDG60_11390	COG1132	(ABC) transporter
CDG60_11400	COG1137	ATPase activity
CDG60_11405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDG60_11415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDG60_11420	COG0517	IMP dehydrogenase activity
CDG60_11420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG60_11465	COG1203	CRISPR-associated helicase, Cas3
CDG60_11470	COG1518	maintenance of DNA repeat elements
CDG60_11495	COG0427	acetyl-CoA hydrolase
CDG60_11500	COG0183	Belongs to the thiolase family
CDG60_11505	COG1960	acyl-CoA dehydrogenase activity
CDG60_11540	COG1643	Atp-dependent helicase
CDG60_11545	COG0450	alkyl hydroperoxide reductase
CDG60_11550	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_11600	COG2391	methyltransferase activity
CDG60_11605	COG2070	2-Nitropropane dioxygenase
CDG60_11655	COG0564	pseudouridine synthase activity
CDG60_11675	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_11735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG60_11745	COG0612	Peptidase, M16
CDG60_11765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_11790	COG0730	response to heat
CDG60_11795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_11820	COG1686	Belongs to the peptidase S11 family
CDG60_11825	COG1252	NADH dehydrogenase
CDG60_11840	COG0415	Belongs to the DNA photolyase family
CDG60_11855	COG3022	response to hydroperoxide
CDG60_11865	COG1301	dicarboxylic acid transport
CDG60_11870	COG4650	regulator
CDG60_11875	COG1690	Belongs to the RtcB family
CDG60_11890	COG0430	RNA-3'-phosphate cyclase activity
CDG60_11905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG60_11915	COG0693	protein deglycase activity
CDG60_11920	COG1960	acyl-CoA dehydrogenase activity
CDG60_11925	COG1301	dicarboxylic acid transport
CDG60_11935	COG3139	Protein of unknown function (DUF1315)
CDG60_11940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG60_11945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG60_11955	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_11970	COG0745	RESPONSE REGULATOR receiver
CDG60_11980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDG60_12000	COG1720	tRNA m6t6A37 methyltransferase activity
CDG60_12015	COG4993	Dehydrogenase
CDG60_12040	COG0798	PFAM Bile acid sodium symporter
CDG60_12050	COG0640	Transcriptional regulator
CDG60_12060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG60_12070	COG0583	DNA-binding transcription factor activity
CDG60_12075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDG60_12080	COG3634	alkyl hydroperoxide reductase activity
CDG60_12110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG60_12405	COG0582	viral genome integration into host DNA
CDG60_12415	COG1131	(ABC) transporter
CDG60_12420	COG0842	Transport permease protein
CDG60_12435	COG2951	lytic endotransglycosylase activity
CDG60_12480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDG60_12485	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG60_12490	COG0024	Methionine aminopeptidase
CDG60_12540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG60_12545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG60_12560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDG60_12565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG60_12570	COG2885	chlorophyll binding
CDG60_12660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG60_12675	COG2234	aminopeptidase activity
CDG60_12680	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDG60_12685	COG3384	dioxygenase
CDG60_12705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG60_12715	COG2878	Part of a membrane complex involved in electron transport
CDG60_12720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDG60_12745	COG0768	penicillin binding
CDG60_12750	COG0742	ribosomal rna small subunit methyltransferase
CDG60_12765	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_12775	COG0204	Acyl-transferase
CDG60_12795	COG1253	flavin adenine dinucleotide binding
CDG60_12800	COG2851	Citrate transporter
CDG60_12830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG60_12835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG60_12840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG60_12910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG60_12955	COG0583	DNA-binding transcription factor activity
CDG60_12975	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG60_12980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDG60_13020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDG60_13050	COG3739	integral membrane protein
CDG60_13065	COG1741	Belongs to the pirin family
CDG60_13075	COG0019	diaminopimelate decarboxylase activity
CDG60_13085	COG3433	isochorismatase activity
CDG60_13085	COG1535	isochorismatase
CDG60_13090	COG1021	2,3-dihydroxybenzoate-AMP ligase
CDG60_13095	COG1169	isochorismate synthase
CDG60_13100	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_13115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDG60_13120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG60_13125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDG60_13130	COG1120	ATPase activity
CDG60_13165	COG0175	sulfate reduction
CDG60_13190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDG60_13195	COG1773	rubredoxin
CDG60_13200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG60_13210	COG0583	DNA-binding transcription factor activity
CDG60_13230	COG0705	Rhomboid family
CDG60_13230	COG0457	Tetratricopeptide repeat
CDG60_13235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDG60_13240	COG4181	ATPase activity
CDG60_13265	COG0500	methyltransferase
CDG60_13270	COG4771	TonB-dependent receptor
CDG60_13290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDG60_13300	COG0306	phosphate transporter
CDG60_13315	COG2852	Protein conserved in bacteria
CDG60_13320	COG2223	nitrite transmembrane transporter activity
CDG60_13325	COG2207	Transcriptional regulator
CDG60_13330	COG0242	peptide deformylase activity
CDG60_13340	COG0477	Major facilitator Superfamily
CDG60_13360	COG1024	Enoyl-CoA hydratase
CDG60_13390	COG1215	transferase activity, transferring glycosyl groups
CDG60_13395	COG0726	polysaccharide deacetylase
CDG60_13395	COG1649	PFAM Uncharacterised BCR, COG1649
CDG60_13405	COG4251	negative regulation of phosphorylation
CDG60_13405	COG2203	Gaf domain
CDG60_13405	COG3706	GGDEF domain
CDG60_13405	COG5001	Diguanylate cyclase
CDG60_13415	COG4681	YaeQ
CDG60_13420	COG0523	cobalamin synthesis protein
CDG60_13450	COG2188	Transcriptional regulator
CDG60_13470	COG0583	DNA-binding transcription factor activity
CDG60_13475	COG2814	Major facilitator Superfamily
CDG60_13480	COG1309	transcriptional regulator
CDG60_13485	COG1607	acyl-coa hydrolase
CDG60_13495	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG60_13500	COG2059	Chromate
CDG60_13505	COG0786	glutamate:sodium symporter activity
CDG60_13520	COG2814	Major facilitator Superfamily
CDG60_13525	COG1289	transmembrane transporter activity
CDG60_13535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDG60_13595	COG2832	Protein of unknown function (DUF454)
CDG60_13610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDG60_13620	COG0643	Histidine kinase
CDG60_13620	COG2198	Histidine kinase
CDG60_13620	COG0643	Histidine kinase
CDG60_13620	COG2198	Histidine kinase
CDG60_13625	COG0840	transmembrane signaling receptor activity
CDG60_13660	COG0442	prolyl-tRNA aminoacylation
CDG60_13705	COG0489	protein tyrosine kinase activity
CDG60_13735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG60_13735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG60_13780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CDG60_13785	COG2081	HI0933 family
CDG60_13790	COG0668	transmembrane transport
CDG60_13805	COG0583	DNA-binding transcription factor activity
CDG60_13815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDG60_13825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_13830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG60_13835	COG0713	ATP synthesis coupled electron transport
CDG60_13845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_13860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDG60_13870	COG0649	NAD binding
CDG60_13870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_13880	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG60_13890	COG0142	geranyltranstransferase activity
CDG60_13895	COG2828	Protein conserved in bacteria
CDG60_13900	COG1113	amino acid transport
CDG60_13910	COG0582	viral genome integration into host DNA
CDG60_14000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG60_14005	COG1530	ribonuclease E activity
CDG60_14010	COG0424	maF-like protein
CDG60_14015	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CDG60_14020	COG1792	Involved in formation and maintenance of cell shape
CDG60_14025	COG1077	Cell shape determining protein MreB Mrl
CDG60_14030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG60_14040	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG60_14050	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_14075	COG0583	DNA-binding transcription factor activity
CDG60_14100	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDG60_14120	COG0270	DNA (cytosine-5-)-methyltransferase activity
CDG60_14140	COG0583	DNA-binding transcription factor activity
CDG60_14160	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_14170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG60_14180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_14200	COG0789	Transcriptional regulator
CDG60_14210	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_14220	COG1028	Short-chain dehydrogenase reductase Sdr
CDG60_14235	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_14245	COG1454	alcohol dehydrogenase
CDG60_14265	COG2072	flavoprotein involved in K transport
CDG60_14270	COG2826	transposase and inactivated derivatives, IS30 family
CDG60_14320	COG2871	sodium ion transport
CDG60_14330	COG3485	protocatechuate 3,4-dioxygenase
CDG60_14335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG60_14340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDG60_14345	COG0583	DNA-binding transcription factor activity
CDG60_14350	COG4948	Mandelate Racemase Muconate Lactonizing
CDG60_14355	COG4829	muconolactone delta-isomerase
CDG60_14360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG60_14365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG60_14370	COG0183	Belongs to the thiolase family
CDG60_14375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG60_14385	COG3177	Filamentation induced by cAMP protein fic
CDG60_14455	COG1802	Transcriptional regulator
CDG60_14460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG60_14465	COG3135	benzoate transporter
CDG60_14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG60_14480	COG0235	Class ii aldolase
CDG60_14485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG60_14500	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CDG60_14510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG60_14580	COG0582	viral genome integration into host DNA
CDG60_14590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG60_14595	COG2814	Major facilitator Superfamily
CDG60_14600	COG1566	PFAM secretion protein HlyD family protein
CDG60_14605	COG2050	protein possibly involved in aromatic compounds catabolism
CDG60_14615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG60_14620	COG1090	epimerase
CDG60_14650	COG4456	Virulence-associated protein
CDG60_14670	COG0354	folic acid binding
CDG60_14690	COG1902	pentaerythritol trinitrate reductase activity
CDG60_14695	COG3659	wide pore channel activity
CDG60_14705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG60_14715	COG1970	mechanosensitive ion channel activity
CDG60_14730	COG2233	PERMEase
CDG60_14740	COG0833	amino acid
CDG60_14795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG60_14805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG60_14880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG60_14890	COG1764	response to oxidative stress
CDG60_14910	COG3264	Mechanosensitive ion channel
CDG60_14910	COG1196	nuclear chromosome segregation
CDG60_14940	COG0037	tRNA processing
CDG60_14975	COG0072	phenylalanine-tRNA ligase activity
CDG60_14980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDG60_15005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDG60_15025	COG1238	metal cluster binding
CDG60_15035	COG0625	glutathione transferase activity
CDG60_15075	COG0318	PFAM AMP-dependent synthetase and ligase
CDG60_15090	COG1660	Displays ATPase and GTPase activities
CDG60_15105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDG60_15110	COG0617	tRNA 3'-terminal CCA addition
CDG60_15115	COG1555	photosystem II stabilization
CDG60_15120	COG3956	TIGRFAM MazG family protein
CDG60_15135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG60_15200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDG60_15205	COG0440	acetolactate synthase activity
CDG60_15210	COG0028	Belongs to the TPP enzyme family
CDG60_15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG60_15250	COG0577	efflux transmembrane transporter activity
CDG60_15250	COG1136	(ABC) transporter
CDG60_15255	COG1538	Outer membrane efflux protein
CDG60_15275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG60_15280	COG1162	GTPase activity
CDG60_15290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDG60_15310	COG3783	Cytochrome b(562)
CDG60_15315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDG60_15320	COG2003	Belongs to the UPF0758 family
CDG60_15325	COG3781	membrane
CDG60_15330	COG0613	PHP domain protein
CDG60_15340	COG2350	Protein conserved in bacteria
CDG60_15360	COG1666	GTP binding
CDG60_15375	COG1607	acyl-coa hydrolase
CDG60_15390	COG3453	Protein conserved in bacteria
CDG60_15390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG60_15450	COG1183	phosphatidylcholine synthase activity
CDG60_15455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDG60_15490	COG1196	nuclear chromosome segregation
CDG60_15490	COG0741	lytic transglycosylase activity
CDG60_15490	COG0739	heme binding
CDG60_15495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDG60_15500	COG1702	phosphate starvation-inducible protein PhoH
CDG60_15540	COG2267	carboxylic ester hydrolase activity
CDG60_15550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDG60_15555	COG0857	belongs to the CobB CobQ family
CDG60_15555	COG0280	phosphate acetyltransferase
CDG60_15565	COG2226	methyltransferase
CDG60_15570	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG60_15570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG60_15590	COG0740	serine-type endopeptidase activity
CDG60_15600	COG4774	siderophore transport
CDG60_15605	COG4774	siderophore transport
CDG60_15620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG60_15630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG60_15630	COG2813	Specifically methylates the guanine in position
CDG60_15645	COG1063	alcohol dehydrogenase
CDG60_15710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDG60_15740	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG60_15775	COG0557	exoribonuclease II activity
CDG60_15790	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CDG60_15810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG60_15815	COG0697	spore germination
CDG60_15845	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDG60_15850	COG1960	acyl-CoA dehydrogenase activity
CDG60_15855	COG2072	flavoprotein involved in K transport
CDG60_15860	COG0203	ribosomal protein L17
CDG60_15865	COG0202	RNA polymerase activity
CDG60_15870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDG60_15875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDG60_15885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDG60_15905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG60_15915	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDG60_15920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG60_15930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDG60_15965	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDG60_15970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG60_15985	COG0088	Forms part of the polypeptide exit tunnel
CDG60_15995	COG0051	transcription antitermination factor activity, RNA binding
CDG60_16005	COG0626	cystathionine gamma-synthase activity
CDG60_16010	COG0433	COG0433 Predicted ATPase
CDG60_16040	COG1017	nitric oxide dioxygenase activity
CDG60_16040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG60_16045	COG1959	2 iron, 2 sulfur cluster binding
CDG60_16060	COG1301	dicarboxylic acid transport
CDG60_16065	COG1946	Acyl-CoA thioesterase
CDG60_16070	COG2937	Belongs to the GPAT DAPAT family
CDG60_16085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDG60_16095	COG1040	competence protein
CDG60_16100	COG0494	nUDIX hydrolase
CDG60_16110	COG0598	Magnesium transport protein CorA
CDG60_16125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG60_16130	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG60_16135	COG1127	ABC transporter
CDG60_16140	COG0513	Belongs to the DEAD box helicase family
CDG60_16150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDG60_16155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG60_16160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG60_16170	COG0408	coproporphyrinogen oxidase activity
CDG60_16190	COG1960	acyl-CoA dehydrogenase activity
CDG60_16205	COG1215	transferase activity, transferring glycosyl groups
CDG60_16235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG60_16250	COG0534	Mate efflux family protein
CDG60_16260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG60_16265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDG60_16285	COG2226	methyltransferase
CDG60_16300	COG1192	Involved in chromosome partitioning
CDG60_16305	COG0628	permease
CDG60_16310	COG2032	superoxide dismutase activity
CDG60_16315	COG1289	transmembrane transporter activity
CDG60_16320	COG2814	Major facilitator Superfamily
CDG60_16365	COG0277	FAD linked oxidase domain protein
CDG60_16375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG60_16380	COG5006	permease, DMT superfamily
CDG60_16400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG60_16405	COG5380	lipid catabolic process
CDG60_16410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDG60_16455	COG0335	large ribosomal subunit rRNA binding
CDG60_16465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG60_16470	COG0228	four-way junction DNA binding
CDG60_16545	COG0194	GDP metabolic process
CDG60_16550	COG1758	RNA polymerase activity
CDG60_16555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG60_16565	COG2906	2 iron, 2 sulfur cluster binding
CDG60_16575	COG3307	-O-antigen
CDG60_16590	COG3307	-O-antigen
CDG60_16595	COG4969	Belongs to the N-Me-Phe pilin family
CDG60_16605	COG2161	toxin-antitoxin pair type II binding
CDG60_16615	COG2194	sulfuric ester hydrolase activity
CDG60_16705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDG60_16710	COG1704	LemA family
CDG60_16720	COG0493	'glutamate synthase
CDG60_16725	COG0067	glutamate synthase
CDG60_16725	COG0069	glutamate synthase activity
CDG60_16725	COG0070	glutamate synthase
CDG60_16775	COG2226	methyltransferase
CDG60_16780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDG60_16785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG60_16790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDG60_16800	COG3116	cell division
CDG60_16810	COG0456	acetyltransferase
CDG60_16815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG60_16835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG60_16885	COG0488	(ABC) transporter
CDG60_16895	COG4221	oxidoreductase activity
CDG60_16910	COG0745	RESPONSE REGULATOR receiver
CDG60_16915	COG2205	protein histidine kinase activity
CDG60_16920	COG0427	acetyl-CoA hydrolase
CDG60_16975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG60_17000	COG1278	Cold shock
CDG60_17005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDG60_17040	COG3158	transport of potassium into the cell
CDG60_17065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG60_17075	COG1335	isochorismatase
CDG60_17095	COG0450	alkyl hydroperoxide reductase
CDG60_17120	COG2814	Major facilitator Superfamily
CDG60_17130	COG0351	phosphomethylpyrimidine kinase
CDG60_17130	COG0352	thiamine-phosphate diphosphorylase activity
CDG60_17130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG60_17155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDG60_17175	COG3706	GGDEF domain
CDG60_17185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG60_17200	COG3162	membrane
CDG60_17205	COG0784	Response regulator, receiver
CDG60_17205	COG2205	protein histidine kinase activity
CDG60_17220	COG0431	NADPH-dependent FMN reductase
CDG60_17245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG60_17250	COG3152	Membrane
CDG60_17255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDG60_17255	COG2755	lipolytic protein G-D-S-L family
CDG60_17260	COG0668	transmembrane transport
CDG60_17265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG60_17270	COG1519	Transferase
CDG60_17280	COG1902	pentaerythritol trinitrate reductase activity
CDG60_17305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDG60_17335	COG0426	domain, Protein
CDG60_17335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG60_17340	COG2119	membrane
CDG60_17370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG60_17380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDG60_17390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG60_17400	COG0189	ligase activity
CDG60_17415	COG0708	Exodeoxyribonuclease III
CDG60_17435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDG60_17470	COG0456	acetyltransferase
CDG60_17495	COG3150	esterase
CDG60_17505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDG60_17510	COG2918	glutathione biosynthetic process
CDG60_17520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDG60_17530	COG2733	membrane
CDG60_17545	COG2801	Transposase and inactivated derivatives
CDG60_17565	COG0436	Aminotransferase
CDG60_17570	COG0534	Mate efflux family protein
CDG60_17605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDG60_17655	COG0385	Bile acid
CDG60_17660	COG1335	isochorismatase
CDG60_17665	COG2814	Major facilitator Superfamily
CDG60_17670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG60_17685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDG60_17690	COG5001	Diguanylate cyclase
CDG60_17695	COG1683	Conserved Protein
CDG60_17700	COG2983	Belongs to the UPF0260 family
CDG60_17705	COG5487	UPF0391 membrane protein
CDG60_17735	COG2818	Glycosylase
CDG60_17740	COG1064	alcohol dehydrogenase
CDG60_17745	COG0156	8-amino-7-oxononanoate synthase activity
CDG60_17770	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDG60_17790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG60_17800	COG2233	PERMEase
CDG60_17805	COG0583	DNA-binding transcription factor activity
CDG60_17815	COG0174	glutamine synthetase
CDG60_17835	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CDG60_17835	COG2885	chlorophyll binding
CDG60_17850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDG60_17860	COG0733	neurotransmitter:sodium symporter activity
CDG60_17865	COG3738	Protein conserved in bacteria
CDG60_17870	COG1012	belongs to the aldehyde dehydrogenase family
CDG60_17880	COG2814	Major facilitator Superfamily
CDG60_17920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG60_17955	COG0484	heat shock protein binding
CDG60_17985	COG2951	lytic endotransglycosylase activity
CDG60_17990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDG60_18005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG60_18020	COG2388	GCN5-related N-acetyl-transferase
CDG60_18025	COG2388	GCN5-related N-acetyl-transferase
CDG60_18035	COG0861	Integral membrane protein TerC family
CDG60_18050	COG0754	glutathionylspermidine amidase activity
CDG60_18065	COG0402	S-adenosylhomocysteine deaminase activity
CDG60_18080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG60_18085	COG3111	PFAM Bacterial OB fold (BOF) protein
CDG60_18095	COG0706	membrane insertase activity
CDG60_18100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDG60_18105	COG0594	ribonuclease P activity
CDG60_18110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
