locus-tag	class	description
C9E88_000010	ENOG4105EPF	Outer membrane porin
C9E88_000020	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_000025	ENOG4105CEY	Amp-dependent synthetase and ligase
C9E88_000030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C9E88_000035	ENOG4108SC4	)-transporter
C9E88_000045	ENOG41062JF	Transcriptional regulator
C9E88_000090	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C9E88_000095	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C9E88_000100	ENOG4105CW7	secretion protein, HlyD family
C9E88_000105	ENOG4108VUY	thioesterase Superfamily protein
C9E88_000110	ENOG4105D52	delta-aminolevulinic acid dehydratase
C9E88_000120	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C9E88_000140	ENOG4107RH8	nuclease SbcCD subunit D
C9E88_000145	ENOG4105EYH	Exonuclease
C9E88_000150	ENOG4105DFA	alanine racemase domain protein
C9E88_000155	ENOG4105CZX	twitching motility protein
C9E88_000160	ENOG4105CZX	twitching motility protein
C9E88_000165	ENOG41090R7	Ferric uptake
C9E88_000175	ENOG4105VDB	UPF0125 protein
C9E88_000190	ENOG4105E7A	Glutamine amidotransferase
C9E88_000200	ENOG4105CAS	nag kinase
C9E88_000215	ENOG4105C4R	Atp-dependent dna helicase
C9E88_000235	ENOG4105C8S	subunit m
C9E88_000240	ENOG4105D65	subunit l
C9E88_000245	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C9E88_000250	ENOG4107UFS	subunit j
C9E88_000255	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C9E88_000265	ENOG4108IEH	NADH dehydrogenase subunit g
C9E88_000270	ENOG4107QIZ	NADH dehydrogenase
C9E88_000275	ENOG4105GKE	subunit e
C9E88_000280	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C9E88_000290	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C9E88_000300	ENOG4105JJR	Histidine kinase
C9E88_000305	ENOG4107EXC	regulatoR
C9E88_000310	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C9E88_000315	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C9E88_000325	ENOG4105CHB	tonB-dependent Receptor
C9E88_000330	ENOG4105DZG	Dehydrogenase
C9E88_000335	ENOG4105TW1	Carbohydrate-selective porin OprB
C9E88_000350	ENOG4107XGZ	Hydrolase
C9E88_000355	ENOG4105DWF	phosphomethylpyrimidine kinase
C9E88_000360	ENOG4108PVD	exported protein
C9E88_000365	ENOG4105DSF	transport protein
C9E88_000380	ENOG4105KWI	UPF0339 protein
C9E88_000390	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C9E88_000405	ENOG4105D3G	Pseudouridine synthase
C9E88_000450	ENOG4108I0Z	Aconitate hydratase
C9E88_000455	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C9E88_000495	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9E88_000500	ENOG4105TW1	Carbohydrate-selective porin OprB
C9E88_000510	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
C9E88_000515	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C9E88_000525	ENOG4107Y60	(LipO)protein
C9E88_000535	ENOG4106B0W	Curli production assembly transport component CsgG
C9E88_000575	ENOG4105CBX	hi0933 family
C9E88_000585	ENOG4107FQ9	ethanolamine ammonia-lyase
C9E88_000590	ENOG4105CPD	ethanolamine ammonia-lyase
C9E88_000595	ENOG4107R55	ethanolamine transporter
C9E88_000615	ENOG4105C2W	permease
C9E88_000625	ENOG4108IQI	permease
C9E88_000635	ENOG4108WHA	ompa motb domain protein
C9E88_000645	ENOG4105CHU	acetyl-coa acetyltransferase
C9E88_000655	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C9E88_000665	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C9E88_000675	ENOG4108R6W	Transcriptional regulator, ARAC family
C9E88_000685	ENOG4105CHU	acetyl-coa acetyltransferase
C9E88_000690	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C9E88_000720	ENOG4108UT2	hemolysin iii
C9E88_000725	ENOG4105CSH	Transporter
C9E88_000740	ENOG4107RZC	phospholipase d
C9E88_000750	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C9E88_000785	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C9E88_000790	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C9E88_000795	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C9E88_000800	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C9E88_000805	ENOG4108UJD	30S ribosomal protein S9
C9E88_000820	ENOG4107MKT	Stringent starvation protein a
C9E88_000825	ENOG4105KB2	stringent starvation protein b
C9E88_000895	ENOG4108SEK	ompa motb domain protein
C9E88_000920	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C9E88_000925	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C9E88_000940	ENOG4105D3R	alkyl hydroperoxide reductase
C9E88_000960	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C9E88_001010	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C9E88_001020	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C9E88_001030	ENOG4108WBT	adenosyltransferase
C9E88_001045	ENOG4105CNG	UPF0061 protein
C9E88_001060	ENOG4105C85	amino acid
C9E88_001065	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C9E88_001070	ENOG4105EB3	Histidine kinase
C9E88_001080	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_001085	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_001105	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
C9E88_001125	ENOG4105UGU	tonB-dependent Receptor
C9E88_001135	ENOG4105C9M	aspartyl-trna synthetase
C9E88_001165	ENOG4108KMV	Glycosyl transferase (Group 1
C9E88_001175	ENOG4107BJW	polysaccharide deacetylase
C9E88_001190	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C9E88_001195	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C9E88_001205	ENOG4105E9K	Isocitrate dehydrogenase
C9E88_001220	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C9E88_001230	ENOG4108V0P	LemA family
C9E88_001245	ENOG4105VIE	preprotein translocase, subunit YajC
C9E88_001250	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C9E88_001255	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C9E88_001265	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C9E88_001280	ENOG4105C6T	cysteine synthase
C9E88_001285	ENOG4105BZU	Histidine kinase
C9E88_001290	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
C9E88_001295	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C9E88_001300	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
C9E88_001315	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C9E88_001320	ENOG4105W8H	transhydrogenase (subunit alpha
C9E88_001325	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C9E88_001330	ENOG4106UX7	integral membrane protein
C9E88_001335	ENOG4108Z4X	TRANSCRIPTIONal
C9E88_001370	ENOG4105DZR	Type I site-specific deoxyribonuclease
C9E88_001385	ENOG4105EKX	Restriction modification system DNA (Specificity
C9E88_001390	ENOG4105CB5	ATP-dependent DNA helicase recG
C9E88_001395	ENOG4105CVR	type I restriction-modification system
C9E88_001415	ENOG4105CFQ	glutamine synthetase
C9E88_001420	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
C9E88_001425	ENOG4105C08	Histidine kinase
C9E88_001430	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C9E88_001435	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C9E88_001440	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C9E88_001445	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C9E88_001505	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C9E88_001510	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C9E88_001515	ENOG4105W5Q	DNA repair protein (RadC
C9E88_001520	ENOG4105FFC	UPF0187 protein
C9E88_001525	ENOG4105DB7	PHP domain protein
C9E88_001535	ENOG4105K9H	YciI-like protein
C9E88_001570	ENOG4105NAU	thioesterase Superfamily protein
C9E88_001585	ENOG4107QPB	Beta-lactamase domain protein
C9E88_001635	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C9E88_001640	ENOG4105D6S	protein involved in catabolism of external DNA
C9E88_001675	ENOG4105E4C	Lytic transglycosylase catalytic
C9E88_001680	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C9E88_001685	ENOG4105C9A	Phoh family
C9E88_001725	ENOG4105GVF	(ABC) transporter
C9E88_001740	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C9E88_001745	ENOG4107S2Z	UPF0761 membrane protein
C9E88_001755	ENOG4108Q5Y	Membrane
C9E88_001765	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
C9E88_001800	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C9E88_001815	ENOG4105DGW	oligopeptidase A
C9E88_001820	ENOG4105VKU	nucleicacid-binding protein
C9E88_001830	ENOG4105EMK	carboxylate amino acid amine transporter
C9E88_001860	ENOG4105C1G	acyl-Coa dehydrogenase
C9E88_001870	ENOG4105CT3	Monooxygenase
C9E88_001875	ENOG4108ZT0	50S ribosomal protein l17
C9E88_001890	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C9E88_001900	ENOG41067V7	50S ribosomal protein L36
C9E88_001905	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C9E88_001920	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C9E88_001930	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C9E88_001935	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C9E88_001955	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C9E88_001970	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C9E88_001985	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C9E88_002000	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C9E88_002005	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C9E88_002010	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C9E88_002015	ENOG41089BK	Glutamine amido-transferase
C9E88_002025	ENOG4105D7A	ATP-binding protein
C9E88_002030	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C9E88_002035	ENOG4105KPV	Transcriptional regulator
C9E88_002055	ENOG4105C29	acyl-CoA thioesterase
C9E88_002060	ENOG4105E55	glycerol-3-phosphate acyltransferase
C9E88_002075	ENOG4105CB5	ATP-dependent DNA helicase recG
C9E88_002080	ENOG4105MJ2	Competence protein
C9E88_002090	ENOG4108URH	decarboxylase
C9E88_002095	ENOG4105D7N	magnesium and cobalt transport protein CorA
C9E88_002115	ENOG4105CY3	ABC transporter, permease
C9E88_002120	ENOG4105DHJ	ABC, transporter
C9E88_002125	ENOG4105C1J	atp-dependent rna helicase
C9E88_002130	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C9E88_002135	ENOG4105ECY	inositol monophosphatase
C9E88_002145	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
C9E88_002155	ENOG4105D4P	Coproporphyrinogen iii oxidase
C9E88_002160	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C9E88_002175	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_002180	ENOG4105CSA	Coproporphyrinogen iii oxidase
C9E88_002190	ENOG4107QI1	Mate efflux family protein
C9E88_002205	ENOG4105NRA	50s ribosomal protein l31 type b
C9E88_002210	ENOG4105WMR	Protein CrcB homolog
C9E88_002245	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
C9E88_002250	ENOG4105IPI	Membrane
C9E88_002255	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C9E88_002265	ENOG4105EM2	membrane
C9E88_002270	ENOG4105VCH	membrane
C9E88_002275	ENOG4107QF7	multi-drug
C9E88_002280	ENOG4105EUB	pirin domain protein
C9E88_002295	ENOG4105CQB	FAD linked oxidase domain protein
C9E88_002300	ENOG4108JQ1	Dehydrogenase
C9E88_002305	ENOG4107AQZ	Membrane
C9E88_002330	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C9E88_002335	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
C9E88_002340	ENOG4107IFA	Lipase (EC 3.1.1.3)
C9E88_002345	ENOG4107IFA	Lipase (EC 3.1.1.3)
C9E88_002350	ENOG4107IFA	Lipase (EC 3.1.1.3)
C9E88_002355	ENOG4107IFA	Lipase (EC 3.1.1.3)
C9E88_002360	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C9E88_002370	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C9E88_002375	ENOG4105K5M	30s ribosomal protein S16
C9E88_002420	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C9E88_002425	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C9E88_002430	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C9E88_002435	ENOG4105KME	endoribonuclease L-psp
C9E88_002445	ENOG4108UQY	Iron-storage protein
C9E88_002455	ENOG4105JNK	Glycosyl transferase (Group 1
C9E88_002470	ENOG4107SJB	teichoic acid biosynthesis
C9E88_002495	ENOG4105BZ1	(ABC) transporter
C9E88_002500	ENOG4105CKK	Glycosyl transferase, family 2
C9E88_002520	ENOG4105HA9	of methanol dehydrogenase type
C9E88_002525	ENOG4108V0P	LemA family
C9E88_002535	ENOG4105BZ8	glutamate synthase
C9E88_002540	ENOG4105CBC	glutamate synthase
C9E88_002560	ENOG4105E4G	Type IV pilus
C9E88_002585	ENOG4108JQC	penicillin-binding protein 1A
C9E88_002590	ENOG4105DHI	Methyltransferase
C9E88_002595	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C9E88_002600	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
C9E88_002605	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C9E88_002610	ENOG4105CJN	penicillin-binding protein
C9E88_002625	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C9E88_002630	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C9E88_002640	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C9E88_002660	ENOG4105C5H	ABC transporter
C9E88_002670	ENOG4105PDP	Short chain dehydrogenase
C9E88_002675	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C9E88_002690	ENOG4105D65	subunit l
C9E88_002695	ENOG4108ZE9	Monovalent cation H antiporter subunit C
C9E88_002700	ENOG4107R4Z	monovalent cation h antiporter subunit d
C9E88_002705	ENOG4105SC1	monovalent cation H antiporter subunit E
C9E88_002710	ENOG4105W4C	monovalent cation H antiporter subunit F
C9E88_002715	ENOG4105KJM	monovalent cation h antiporter subunit g
C9E88_002720	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C9E88_002730	ENOG4105CHV	Transcription elongation factor NusA
C9E88_002760	ENOG4107EJC	Preprotein translocase subunit SecG
C9E88_002770	ENOG4107QHF	type ii secretion system protein e
C9E88_002785	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C9E88_002795	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C9E88_002800	ENOG4105NBK	UPF0345 protein
C9E88_002805	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C9E88_002815	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C9E88_002830	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
C9E88_002845	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C9E88_002860	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C9E88_002865	ENOG41087AY	ADP-Ribose pyrophosphatase
C9E88_002870	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C9E88_002875	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9E88_002880	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C9E88_002885	ENOG4105CNI	cell division protein FtsW
C9E88_002900	ENOG4105CE1	Ferrous iron transport protein b
C9E88_002910	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C9E88_002915	ENOG4105T95	Thiol disulfide interChange protein
C9E88_002920	ENOG4105D6E	homoserine dehydrogenase
C9E88_002930	ENOG41061WM	D-Alanyl-D-Alanine
C9E88_002940	ENOG4107TUY	Histidine kinase
C9E88_002945	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9E88_002950	ENOG4105CN1	protease
C9E88_002955	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C9E88_002960	ENOG4108K5H	permease YjgP YjgQ family protein
C9E88_002965	ENOG4108M8S	permease YjgP YjgQ family protein
C9E88_002990	ENOG4105DQR	SNARE associated Golgi
C9E88_003005	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C9E88_003015	ENOG4105BZU	Histidine kinase
C9E88_003030	ENOG4105C0P	Mg chelatase subunit ChlI
C9E88_003045	ENOG4105EPF	Outer membrane porin
C9E88_003050	ENOG4105F0N	pyrophosphate phospho-hydrolase
C9E88_003065	ENOG4105CEY	Amp-dependent synthetase and ligase
C9E88_003070	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9E88_003075	ENOG41079KZ	Major Facilitator Superfamily
C9E88_003080	ENOG4105EN6	Membrane
C9E88_003085	ENOG4105K5B	UPF0225 protein
C9E88_003090	ENOG4105EE5	Membrane protein terC
C9E88_003095	ENOG4108URH	decarboxylase
C9E88_003105	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C9E88_003115	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C9E88_003130	ENOG4105CCT	upf0313 protein
C9E88_003135	ENOG4105ERG	peptidase m48, ste24p
C9E88_003165	ENOG4107Z3H	Transcriptional regulator, TetR family
C9E88_003200	ENOG4105C79	DNA protecting protein DprA
C9E88_003220	ENOG4108V06	Glutathione peroxidase
C9E88_003235	ENOG4105EUB	pirin domain protein
C9E88_003245	ENOG4105DSB	aldose 1-epimerase
C9E88_003265	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C9E88_003275	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C9E88_003290	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C9E88_003315	ENOG4105FDK	ABC transporter
C9E88_003320	ENOG4105FAV	ABC, transporter
C9E88_003325	ENOG4105SF0	DinB family
C9E88_003335	ENOG410829K	Lysine exporter protein (Lyse ygga)
C9E88_003340	ENOG4105EZR	dyp-type peroxidase family protein
C9E88_003375	ENOG4105CS6	Rhs element vgr protein
C9E88_003380	ENOG4105CHM	Aminotransferase
C9E88_003385	ENOG4107QJQ	Mate efflux family protein
C9E88_003400	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C9E88_003405	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
C9E88_003445	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C9E88_003450	ENOG4105BZU	Histidine kinase
C9E88_003465	ENOG4105EUB	pirin domain protein
C9E88_003470	ENOG4105BZU	Histidine kinase
C9E88_003485	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
C9E88_003490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C9E88_003500	ENOG4108VBZ	doxx family
C9E88_003505	ENOG4105DQR	SNARE associated Golgi
C9E88_003520	ENOG4107QJE	Chromosome Partitioning Protein
C9E88_003610	ENOG4105C0A	alcohol dehydrogenase
C9E88_003620	ENOG4107RR1	TRANSCRIPTIONal
C9E88_003660	ENOG4105C0D	helicase
C9E88_003675	ENOG4105DM4	PTS System
C9E88_003680	ENOG4105DE4	1-phosphofructokinase
C9E88_003685	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C9E88_003735	ENOG4108IG5	Transcriptional regulator
C9E88_003740	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C9E88_003750	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C9E88_003755	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C9E88_003760	ENOG4108ZAI	phosphatidylglycerophosphatase a
C9E88_003765	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C9E88_003770	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C9E88_003775	ENOG4107QKV	phosphomannomutase
C9E88_003780	ENOG4105CMR	udp-glucose 4-epimerase
C9E88_003790	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C9E88_003795	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C9E88_003805	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C9E88_003810	ENOG4106CD9	glycosyl transferase group 1
C9E88_003815	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
C9E88_003840	ENOG4105FGF	GDP-mannose mannosyl hydrolase
C9E88_003845	ENOG4105C30	Nad-dependent epimerase dehydratase
C9E88_003855	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C9E88_003865	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C9E88_003870	ENOG4107WZ3	Transferase
C9E88_003875	ENOG4105D3Q	Sugar transferase
C9E88_003880	ENOG4105CGN	Glycosyl transferase (Group 1
C9E88_003885	ENOG4107T8Q	Glycosyl transferase (Group 1
C9E88_003890	ENOG4105CG5	Glycosyl transferase (Group 1
C9E88_003900	ENOG4108UW5	maltose o-acetyltransferase
C9E88_003915	ENOG4107QQG	Dehydrogenase
C9E88_003920	ENOG4105DAY	polysaccharide export protein
C9E88_003930	ENOG4105D75	Capsular exopolysaccharide family
C9E88_003935	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C9E88_003940	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C9E88_003955	ENOG4105CEN	a g-specific adenine glycosylase
C9E88_003960	ENOG4105FAA	peptidase M23
C9E88_003970	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C9E88_003975	ENOG4105DQ4	alcohol dehydrogenase
C9E88_003995	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C9E88_004000	ENOG4108YSG	O-Antigen polymerase
C9E88_004020	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C9E88_004025	ENOG4108JGH	Tetr family transcriptional regulator
C9E88_004050	ENOG4105BZU	Histidine kinase
C9E88_004100	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C9E88_004105	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C9E88_004155	ENOG4105C8J	)-transporter
C9E88_004185	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C9E88_004235	ENOG4108821	RND type efflux pump
C9E88_004240	ENOG4108821	RND type efflux pump
C9E88_004250	ENOG4105C5H	ABC transporter
C9E88_004260	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9E88_004270	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C9E88_004275	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C9E88_004280	ENOG4105VG0	50S ribosomal protein l34
C9E88_004290	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C9E88_004295	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C9E88_004325	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C9E88_004330	ENOG4107QUY	Guanine deaminase
C9E88_004335	ENOG4105DU1	integral membrane protein, terc
C9E88_004340	ENOG4105F27	Major Facilitator
C9E88_004365	ENOG4105DFU	Cell wall formation (By similarity)
C9E88_004375	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C9E88_004380	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C9E88_004385	ENOG4105CVE	Lytic murein transglycosylase
C9E88_004390	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C9E88_004395	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C9E88_004435	ENOG4105D2S	major facilitator superfamily
C9E88_004440	ENOG4105D2S	major facilitator superfamily
C9E88_004470	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
C9E88_004480	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C9E88_004485	ENOG4105DTN	riboflavin biosynthesis protein ribF
C9E88_004505	ENOG4108R86	Transcriptional regulator
C9E88_004510	ENOG4108VM9	ABC, transporter
C9E88_004515	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C9E88_004520	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C9E88_004525	ENOG4105GVF	(ABC) transporter
C9E88_004530	ENOG4107QZM	n-acetylglutamate synthase
C9E88_004550	ENOG4105UBK	short-chain dehydrogenase reductase
C9E88_004555	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C9E88_004560	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C9E88_004575	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C9E88_004580	ENOG4105HSS	phospholipase C
C9E88_004585	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C9E88_004590	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
C9E88_004595	ENOG4105CJR	Integral membrane protein (MviN
C9E88_004605	ENOG4108ZZ3	UPF0260 protein
C9E88_004615	ENOG4105BZU	Histidine kinase
C9E88_004620	ENOG4105D1H	recombination factor protein RarA
C9E88_004635	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C9E88_004640	ENOG4108SC4	)-transporter
C9E88_004650	ENOG4108RWI	nicotinamidase
C9E88_004655	ENOG4105C09	Bile acid
C9E88_004665	ENOG4105EAC	phosphoserine phosphatase
C9E88_004685	ENOG4105CH6	catalase
C9E88_004695	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C9E88_004700	ENOG4105KHC	sulfurtransferase
C9E88_004725	ENOG4106BRA	Membrane
C9E88_004740	ENOG4105D9M	gamma-glutamylcysteine synthetase
C9E88_004745	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C9E88_004755	ENOG4105IPS	esterase
C9E88_004760	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9E88_004765	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
C9E88_004770	ENOG4105C32	Amino acid ABC transporter (Permease)
C9E88_004780	ENOG4105C0Z	ABC transporter
C9E88_004785	ENOG4108IV0	ABC, transporter
C9E88_004795	ENOG4108Z7F	N-acetyltransferase
C9E88_004820	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C9E88_004830	ENOG4105BZU	Histidine kinase
C9E88_004835	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C9E88_004855	ENOG4105CGK	Exodeoxyribonuclease III
C9E88_004860	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C9E88_004870	ENOG4105VEQ	Cold shock protein
C9E88_004875	ENOG4105D7Z	glutathione synthase
C9E88_004885	ENOG4105DFU	Cell wall formation (By similarity)
C9E88_004890	ENOG4105CPF	Cell wall formation (By similarity)
C9E88_004895	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C9E88_004900	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C9E88_004905	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C9E88_004925	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C9E88_004930	ENOG4107QSN	dihydrolipoamide acetyltransferase
C9E88_004950	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C9E88_004965	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C9E88_004990	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9E88_004995	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C9E88_005015	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C9E88_005020	ENOG4107T8P	acyl-Coa dehydrogenase
C9E88_005025	ENOG4108R6K	riboflavin synthase, subunit alpha
C9E88_005035	ENOG4105FBW	Monooxygenase
C9E88_005040	ENOG4108UZX	fmn reductase
C9E88_005055	ENOG4105BZU	Histidine kinase
C9E88_005060	ENOG41062QD	Membrane
C9E88_005085	ENOG4105BZU	Histidine kinase
C9E88_005095	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C9E88_005110	ENOG4105RA2	Membrane
C9E88_005115	ENOG4105ETU	transcriptional activator (TenA
C9E88_005125	ENOG4107RDB	Major Facilitator
C9E88_005130	ENOG4108UUM	single-stranded DNA-binding protein
C9E88_005145	ENOG4105D3R	alkyl hydroperoxide reductase
C9E88_005155	ENOG4105CHJ	isochorismatase hydrolase
C9E88_005160	ENOG4105EUB	pirin domain protein
C9E88_005190	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C9E88_005235	ENOG4105CUV	Homoserine Kinase
C9E88_005255	ENOG4105CUB	amino acid
C9E88_005265	ENOG410631K	Membrane
C9E88_005285	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C9E88_005365	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
C9E88_005385	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C9E88_005400	ENOG4108HRK	Histidine kinase
C9E88_005405	ENOG4108NEV	two component transcriptional regulator, LytTR family
C9E88_005410	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C9E88_005435	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
C9E88_005450	ENOG4105GVR	general secretion pathway protein D
C9E88_005460	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C9E88_005500	ENOG4105PM1	preprotein translocase subunit SecE
C9E88_005505	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C9E88_005515	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C9E88_005520	ENOG4108VZM	50s ribosomal protein L10
C9E88_005530	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C9E88_005560	ENOG4105D3Y	Na H antiporter
C9E88_005565	ENOG4105EIF	outer membrane protein W
C9E88_005575	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C9E88_005600	ENOG4107ZXU	DSBA oxidoreductase
C9E88_005610	ENOG4105CYC	Transferase
C9E88_005615	ENOG4105E0F	Histidine kinase
C9E88_005620	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C9E88_005650	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C9E88_005660	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C9E88_005670	ENOG4105CSR	polyphosphate kinase 2
C9E88_005680	ENOG4105DSY	exodeoxyribonuclease V, gamma
C9E88_005685	ENOG4107QKA	exodeoxyribonuclease V beta
C9E88_005690	ENOG4107QYX	exodeoxyribonuclease v alpha
C9E88_005700	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C9E88_005705	ENOG4107QUT	magnesium and cobalt transport protein CorA
C9E88_005715	ENOG4105Z2P	Protein of unknown function (DUF465)
C9E88_005720	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
C9E88_005745	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C9E88_005755	ENOG4105C25	Primosomal protein n'
C9E88_005760	ENOG4105D7Q	type ii secretion system
C9E88_005765	ENOG4108VAU	general secretion pathway protein G
C9E88_005780	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C9E88_005785	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C9E88_005790	ENOG4108JU5	Magnesium and cobalt efflux protein
C9E88_005795	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C9E88_005800	ENOG4105CS6	Rhs element vgr protein
C9E88_005815	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C9E88_005825	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C9E88_005840	ENOG4105C5X	domain protein
C9E88_005850	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
C9E88_005860	ENOG4105BZ8	glutamate synthase
C9E88_005885	ENOG4105C5I	Dehydrogenase
C9E88_005950	ENOG41067S9	phage shock protein C, PspC
C9E88_005985	ENOG4105C03	ribonuclease
C9E88_005995	ENOG4105EI2	Pseudouridine synthase
C9E88_006005	ENOG4105IKQ	hydratase
C9E88_006010	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
C9E88_006015	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
C9E88_006020	ENOG4105EPF	Outer membrane porin
C9E88_006030	ENOG4108W5M	transcriptional regulator
C9E88_006035	ENOG4105FUY	alpha subunit
C9E88_006050	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
C9E88_006055	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
C9E88_006060	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
C9E88_006090	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C9E88_006105	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_006110	ENOG4108YXU	transcriptional regulator AsnC family
C9E88_006125	ENOG4105ECQ	AraC Family Transcriptional Regulator
C9E88_006135	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
C9E88_006175	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C9E88_006190	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C9E88_006255	ENOG4105D1S	lipid A biosynthesis
C9E88_006270	ENOG4105C5H	ABC transporter
C9E88_006275	ENOG41069P5	Protein slyX homolog
C9E88_006290	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C9E88_006315	ENOG4105BZW	Glycerate kinase
C9E88_006330	ENOG4105C4R	Atp-dependent dna helicase
C9E88_006335	ENOG4105VFU	Rna-binding protein
C9E88_006360	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C9E88_006365	ENOG4105W0E	50S ribosomal protein L33
C9E88_006370	ENOG4105KDC	50s ribosomal protein l28
C9E88_006375	ENOG4107RGH	Aldehyde dehydrogenase
C9E88_006385	ENOG4105CIY	formyltetrahydrofolate deformylase
C9E88_006470	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C9E88_006500	ENOG4105DWV	Homoserine O-trans-acetylase
C9E88_006510	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C9E88_006520	ENOG4107E2E	PKHD-type hydroxylase
C9E88_006525	ENOG4108IU3	tonb-dependent siderophore receptor
C9E88_006530	ENOG4108ESX	Receptor
C9E88_006535	ENOG4108ESX	Receptor
C9E88_006545	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C9E88_006565	ENOG4107GFK	fumarate
C9E88_006590	ENOG4108DNC	Involved in acetate metabolism (By similarity)
C9E88_006595	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C9E88_006620	ENOG4105CN1	protease
C9E88_006625	ENOG4105BZU	Histidine kinase
C9E88_006645	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C9E88_006660	ENOG4105F8V	Hydrolase, tatD family
C9E88_006665	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C9E88_006675	ENOG4105VW4	glutaredoxin 3
C9E88_006685	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C9E88_006690	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C9E88_006700	ENOG4105CUZ	uba thif-type nad fad binding protein
C9E88_006705	ENOG4105CS6	Rhs element vgr protein
C9E88_006735	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C9E88_006740	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C9E88_006745	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C9E88_006770	ENOG4105C7K	acetolactate synthase
C9E88_006775	ENOG4108ZP8	Acetolactate synthase small subunit
C9E88_006805	ENOG4108XG2	Histidine kinase
C9E88_006820	ENOG4105WVQ	Fe-S assembly protein IscX
C9E88_006840	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
C9E88_006860	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C9E88_006880	ENOG4105DXN	mazG family
C9E88_006885	ENOG4105KQC	Competence protein
C9E88_006890	ENOG4105DJ0	Poly(A) Polymerase
C9E88_006895	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9E88_006910	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C9E88_006925	ENOG4105CEY	Amp-dependent synthetase and ligase
C9E88_006965	ENOG4105CYM	Glutathione S-transferase
C9E88_006975	ENOG4105W39	Membrane
C9E88_006995	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C9E88_007030	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C9E88_007035	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C9E88_007050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C9E88_007060	ENOG4105C9X	ppx gppa phosphatase
C9E88_007070	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C9E88_007075	ENOG4105II7	pyrroline-5-carboxylate reductase
C9E88_007080	ENOG4108VIA	integral membrane protein
C9E88_007085	ENOG4105C2M	dna polymerase I
C9E88_007105	ENOG4107QHF	type ii secretion system protein e
C9E88_007115	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C9E88_007195	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C9E88_007200	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C9E88_007210	ENOG4105CRQ	synthase (Component I)
C9E88_007250	ENOG4105P8F	nudix hydrolase
C9E88_007255	ENOG4108Z0R	Transferase
C9E88_007260	ENOG41072GX	Peptidase M22 Glycoprotease
C9E88_007265	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C9E88_007280	ENOG4105C4W	S-formylglutathione hydrolase
C9E88_007290	ENOG4105DJV	ribulose-phosphate 3-epimerase
C9E88_007300	ENOG4105E3B	Multicopper oxidase
C9E88_007315	ENOG4105KPY	Small multidrug resistance protein
C9E88_007320	ENOG4105KPY	Small multidrug resistance protein
C9E88_007335	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
C9E88_007370	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9E88_007390	ENOG4105HF0	Membrane
C9E88_007410	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C9E88_007430	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
C9E88_007435	ENOG4108UWD	Iron-storage protein
C9E88_007440	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9E88_007450	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C9E88_007460	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C9E88_007465	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C9E88_007480	ENOG4105FE9	pseudouridine synthase
C9E88_007485	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C9E88_007490	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C9E88_007500	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C9E88_007505	ENOG4108BPE	-transporting atpase
C9E88_007510	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C9E88_007515	ENOG4105VGS	50s ribosomal protein l32
C9E88_007520	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C9E88_007525	ENOG4105CHR	reductase
C9E88_007535	ENOG4109066	lysm domain bon superfamily protein
C9E88_007540	ENOG4108YXA	Membrane
C9E88_007555	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C9E88_007580	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
C9E88_007590	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C9E88_007595	ENOG4105C3M	thioredoxin reductase
C9E88_007600	ENOG4105CNU	cell division protein FtsK
C9E88_007620	ENOG4105EUR	Domain-Containing protein
C9E88_007640	ENOG4107QMS	site-determining protein
C9E88_007655	ENOG4106HNH	Acyl-transferase
C9E88_007660	ENOG4108ZG0	Ompa motb domain protein
C9E88_007665	ENOG4105DUM	transcriptional regulator, lysR family
C9E88_007670	ENOG4105DP0	ferredoxin-NADP reductase
C9E88_007685	ENOG4105D1F	ATP-binding protein
C9E88_007720	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C9E88_007730	ENOG4105D0S	secretion protein (HlyD
C9E88_007740	ENOG4108UNF	response regulator
C9E88_007745	ENOG4105M3Z	response regulator
C9E88_007750	ENOG4108ZGA	chew protein
C9E88_007755	ENOG4105C8Q	Methyl-accepting chemotaxis
C9E88_007760	ENOG4105CBS	Chea signal transduction histidine kinase
C9E88_007785	ENOG4105WD1	Membrane
C9E88_007845	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C9E88_007855	ENOG4105EM2	membrane
C9E88_007860	ENOG4105C2C	drug resistance transporter, Bcr CflA
C9E88_007875	ENOG4105D6U	Sodium Glutamate Symporter
C9E88_007880	ENOG4105BZG	amino acid carrier protein
C9E88_007885	ENOG4105D78	K07001 NTE family protein
C9E88_007900	ENOG4105YIP	Tetr family transcriptional regulator
C9E88_007905	ENOG4105CZM	Major Facilitator
C9E88_007910	ENOG4108W5M	transcriptional regulator
C9E88_007925	ENOG4105CKI	cobalamin synthesis protein
C9E88_007930	ENOG4108VWS	Yaeq family
C9E88_007945	ENOG4105BZU	Histidine kinase
C9E88_007980	ENOG4105CSH	Transporter
C9E88_008000	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C9E88_008010	ENOG4105EU0	Major facilitator Superfamily
C9E88_008020	ENOG4105C4R	Atp-dependent dna helicase
C9E88_008025	ENOG4105CMT	Dihydroxyacetone kinase
C9E88_008030	ENOG4105BZU	Histidine kinase
C9E88_008035	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
C9E88_008050	ENOG4105C3R	Methionine synthase
C9E88_008055	ENOG4105CJ3	phosphate transporter
C9E88_008085	ENOG4105D05	Receptor
C9E88_008105	ENOG4108UJV	acyl-CoA thioesterase i
C9E88_008110	ENOG4108I0Y	(ABC) transporter
C9E88_008115	ENOG4105CV6	ABC transporter, permease
C9E88_008120	ENOG4107U91	Rhomboid family
C9E88_008135	ENOG4105WH1	Two component transcriptional regulator luxr family
C9E88_008140	ENOG4105C5Q	Transcriptional regulator
C9E88_008145	ENOG4106HB6	Alpha beta hydrolase
C9E88_008150	ENOG4107QZF	nitrite reductase NADPH large subunit
C9E88_008155	ENOG4105VCQ	rubredoxin
C9E88_008160	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C9E88_008185	ENOG4105CKW	Inner membrane protein yedI
C9E88_008190	ENOG4105CGZ	zinc metallopeptidase
C9E88_008200	ENOG4105EEQ	Na H antiporter
C9E88_008250	ENOG4105C4K	Nad synthetase
C9E88_008260	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
C9E88_008265	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
C9E88_008275	ENOG4108R85	Short chain dehydrogenase
C9E88_008280	ENOG4105F95	Monooxygenase
C9E88_008290	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
C9E88_008295	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
C9E88_008305	ENOG4105E33	succinate dehydrogenase
C9E88_008310	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C9E88_008315	ENOG4105C7S	Dehydrogenase
C9E88_008320	ENOG4107QN2	dihydrolipoyl dehydrogenase
C9E88_008330	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C9E88_008335	ENOG4107S78	Band 7 protein
C9E88_008350	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C9E88_008355	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
C9E88_008375	ENOG4105NTW	Transcriptional regulator
C9E88_008395	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C9E88_008415	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C9E88_008430	ENOG4105CSH	Transporter
C9E88_008435	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C9E88_008445	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C9E88_008450	ENOG4105CBD	Diacylglycerol kinase
C9E88_008455	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C9E88_008485	ENOG4108UAJ	Transcriptional regulator
C9E88_008495	ENOG4105E0K	tonB-dependent siderophore receptor
C9E88_008500	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
C9E88_008505	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
C9E88_008525	ENOG4106H78	methyltransferase
C9E88_008530	ENOG4105CJN	penicillin-binding protein
C9E88_008555	ENOG4105CSM	endonuclease III
C9E88_008560	ENOG4108R3D	Electron transport complex
C9E88_008565	ENOG4105D82	Glutamate dehydrogenase
C9E88_008575	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C9E88_008585	ENOG4107VAM	peptidase, m28
C9E88_008595	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C9E88_008610	ENOG4105DDY	UPF0142 protein ycaO
C9E88_008640	ENOG4107RAQ	aminopeptidase
C9E88_008655	ENOG4108IND	Tetr family transcriptional regulator
C9E88_008665	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C9E88_008670	ENOG4105D0A	hydroxylase
C9E88_008675	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C9E88_008690	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C9E88_008720	ENOG4105E09	nadh pyrophosphatase
C9E88_008730	ENOG4107RZZ	dna polymerase iii epsilon subunit
C9E88_008735	ENOG4105E9H	Lytic Murein transglycosylase
C9E88_008745	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
C9E88_008750	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
C9E88_008755	ENOG4108JQ5	ABC transporter
C9E88_008790	ENOG4108IQI	permease
C9E88_008800	ENOG4108IQI	permease
C9E88_008825	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
C9E88_008830	ENOG4105EKE	dihydroorotase
C9E88_008835	ENOG4105BZU	Histidine kinase
C9E88_008850	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9E88_008905	ENOG4105MZU	cell filamentation protein
C9E88_008915	ENOG4105CVR	type I restriction-modification system
C9E88_008985	ENOG4105C2I	pirin domain protein
C9E88_009000	ENOG4105NX3	Membrane
C9E88_009025	ENOG4105EUJ	GTP cyclohydrolase i
C9E88_009045	ENOG4107QYG	anthranilate phosphoribosyltransferase
C9E88_009050	ENOG4105DDQ	anthranilate synthase
C9E88_009055	ENOG41084CK	capsule polysaccharide
C9E88_009060	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C9E88_009080	ENOG4108TJN	glycosyl transferase group 1
C9E88_009100	ENOG4107RXY	Glycosyl transferase
C9E88_009105	ENOG4105E12	capsule polysaccharide
C9E88_009110	ENOG4108TJN	glycosyl transferase group 1
C9E88_009115	ENOG4105C5F	glutamine synthetase
C9E88_009135	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
C9E88_009145	ENOG4108W5M	transcriptional regulator
C9E88_009200	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C9E88_009205	ENOG4107QNR	UPF0135 protein
C9E88_009210	ENOG4105C0H	protease
C9E88_009220	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C9E88_009225	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
C9E88_009230	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
C9E88_009235	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
C9E88_009240	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
C9E88_009245	ENOG4105C2W	permease
C9E88_009265	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C9E88_009280	ENOG4105E2B	Taurine dioxygenase
C9E88_009300	ENOG4105BZU	Histidine kinase
C9E88_009310	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C9E88_009350	ENOG4105ECR	NmrA family
C9E88_009355	ENOG4105KVH	Transcriptional regulator
C9E88_009370	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C9E88_009375	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C9E88_009385	ENOG4108JPW	Aminotransferase
C9E88_009390	ENOG4105DY8	decarboxylase
C9E88_009400	ENOG4105CVA	phosphate
C9E88_009405	ENOG4105C8U	phosphate abc transporter
C9E88_009415	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C9E88_009430	ENOG4105ERU	peptidase
C9E88_009460	ENOG4107QTF	adenylosuccinate lyase
C9E88_009465	ENOG41075W9	High frequency lysogenization protein HflD homolog
C9E88_009470	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C9E88_009480	ENOG4108JCI	Transcriptional regulator
C9E88_009495	ENOG4108Z0R	Transferase
C9E88_009500	ENOG4105DZ1	carboxypeptidase
C9E88_009520	ENOG4108K5P	(LipO)protein
C9E88_009525	ENOG4105EJC	lysr family transcriptional regulator
C9E88_009530	ENOG4105C8Y	Acetylornithine aminotransferase
C9E88_009535	ENOG4105M2J	Glutaredoxin
C9E88_009540	ENOG4105DAN	ATP-dependent protease
C9E88_009555	ENOG4105DHU	Bile acid
C9E88_009580	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
C9E88_009585	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C9E88_009590	ENOG4105D22	carbon starvation protein
C9E88_009595	ENOG4105VCD	cytoplasmic protein
C9E88_009600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C9E88_009610	ENOG4105F8C	transglutaminase domain-containing protein
C9E88_009720	ENOG4108UKZ	OsmC family
C9E88_009725	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C9E88_009730	ENOG4105CPC	Aldo Keto reductase
C9E88_009735	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9E88_009785	ENOG4105CXT	aspartate transcarbamylase
C9E88_009790	ENOG4105CD3	dihydroorotase
C9E88_009795	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C9E88_009820	ENOG4107RGH	Aldehyde dehydrogenase
C9E88_009825	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C9E88_009835	ENOG4105BZU	Histidine kinase
C9E88_009840	ENOG4105CHH	sulfate transporter
C9E88_009845	ENOG4108K3A	Glutathione S-transferase
C9E88_009865	ENOG4105M08	Membrane
C9E88_009875	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C9E88_009885	ENOG4105VEQ	Cold shock protein
C9E88_009890	ENOG4105C1J	atp-dependent rna helicase
C9E88_009900	ENOG41069NU	Nitroreductase
C9E88_009925	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C9E88_009935	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C9E88_009950	ENOG4105C5I	Dehydrogenase
C9E88_009955	ENOG4105ERG	peptidase m48, ste24p
C9E88_009970	ENOG4105KTH	gatB Yqey
C9E88_009975	ENOG4105VCC	30S ribosomal protein S21
C9E88_009980	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C9E88_010005	ENOG4105D9P	serine threonine protein kinase
C9E88_010070	ENOG4105EXC	Acyl-transferase
C9E88_010075	ENOG4108MEJ	flavin reductase domain protein
C9E88_010080	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C9E88_010115	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C9E88_010140	ENOG4105D3G	Pseudouridine synthase
C9E88_010145	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
C9E88_010175	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C9E88_010180	ENOG4105EJ2	Transcriptional regulator
C9E88_010200	ENOG4107QS8	(LipO)protein
C9E88_010205	ENOG4107BJW	polysaccharide deacetylase
C9E88_010210	ENOG4105CND	Glycosyl transferase, family 2
C9E88_010220	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C9E88_010225	ENOG4105EA8	2-Nitropropane dioxygenase
C9E88_010245	ENOG41066VF	YeeE YedE family protein
C9E88_010265	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C9E88_010270	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C9E88_010300	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C9E88_010325	ENOG4105C2X	Arabinose 5-phosphate isomerase
C9E88_010330	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
C9E88_010340	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
C9E88_010345	ENOG4108IUZ	ABC transporter
C9E88_010355	ENOG4108JJA	ABC, transporter
C9E88_010370	ENOG4108UW5	maltose o-acetyltransferase
C9E88_010390	ENOG4108Z4U	Ferredoxin
C9E88_010400	ENOG4105BZU	Histidine kinase
C9E88_010430	ENOG4105C0B	DNA polymerase III (alpha subunit)
C9E88_010440	ENOG4108UMI	ABC transporter, permease
C9E88_010445	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C9E88_010465	ENOG4108YYQ	gCN5-related N-acetyltransferase
C9E88_010475	ENOG4105C12	Phosphoribosylglycinamide synthetase
C9E88_010480	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C9E88_010485	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
C9E88_010530	ENOG4108SC4	)-transporter
C9E88_010540	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9E88_010545	ENOG4105CUX	Signal transduction histidine kinase
C9E88_010565	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C9E88_010570	ENOG4105KNE	Phosphatidate cytidylyltransferase
C9E88_010580	ENOG4105DZP	Membrane-associated zinc metalloprotease
C9E88_010585	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E88_010605	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C9E88_010620	ENOG4105Y3E	Modulates RecA activity (By similarity)
C9E88_010630	ENOG4105VEJ	Heat shock protein
C9E88_010635	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
C9E88_010640	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
C9E88_010660	ENOG4105K4T	epimerase
C9E88_010665	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C9E88_010675	ENOG4105WH1	Two component transcriptional regulator luxr family
C9E88_010680	ENOG4105BZU	Histidine kinase
C9E88_010685	ENOG4105EZE	Cupin 4 family protein
C9E88_010700	ENOG4108UHJ	MAF-like protein
C9E88_010710	ENOG4105BZA	Phosphoglycerate kinase
C9E88_010720	ENOG4105D2N	Aldolase
C9E88_010725	ENOG4108TZV	Membrane
C9E88_010740	ENOG4108RCM	Nitroreductase
C9E88_010775	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C9E88_010785	ENOG4105CX6	glutaminyL-tRNA synthetase
C9E88_010790	ENOG4105FFC	UPF0187 protein
C9E88_010795	ENOG4105C4R	Atp-dependent dna helicase
C9E88_010820	ENOG4105C26	Dehydrogenase
C9E88_010825	ENOG4105EW9	transcriptional regulator AsnC family
C9E88_010830	ENOG4105CK7	Sodium proline symporter
C9E88_010835	ENOG4108IJ0	Aspartate ammonia-lyase
C9E88_010845	ENOG4108JA2	transcriptioN-repair coupling factor
C9E88_010855	ENOG4105F8J	Adenylate Guanylate cyclase
C9E88_010860	ENOG4108ZIT	Ferredoxin, 2FE-2S
C9E88_010875	ENOG4108Z4V	iron-sulfur cluster assembly
C9E88_010880	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
C9E88_010890	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C9E88_010905	ENOG4105K70	DNA-binding protein
C9E88_010910	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C9E88_010940	ENOG4105PV3	Inner membrane protein yqiJ
C9E88_010970	ENOG4105HDD	phospholipase
C9E88_010975	ENOG4105CZN	Potassium uptake protein
C9E88_010995	ENOG4105C7B	Threonine dehydratase
C9E88_011000	ENOG4105E66	phosphoriboisomerase A
C9E88_011035	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C9E88_011045	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C9E88_011050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9E88_011075	ENOG4105CR4	methylisocitrate lyase
C9E88_011080	ENOG4105BZN	citrate synthase
C9E88_011085	ENOG4105CEV	competence damage-inducible protein
C9E88_011100	ENOG4108MJ3	acetyltransferase
C9E88_011105	ENOG4105C1G	acyl-Coa dehydrogenase
C9E88_011110	ENOG4105C1G	acyl-Coa dehydrogenase
C9E88_011130	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C9E88_011175	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C9E88_011180	ENOG4107TSN	permease
C9E88_011190	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C9E88_011200	ENOG4105E7U	AraC family transcriptional regulator
C9E88_011205	ENOG4105EEF	Alkane 1-monooxygenase
C9E88_011210	ENOG4108Z66	YbaK ebsC protein
C9E88_011240	ENOG4105EYM	Major Facilitator superfamily
C9E88_011255	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
C9E88_011265	ENOG4108YZT	Adenosylcobinamide kinase
C9E88_011270	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C9E88_011320	ENOG4105CMR	udp-glucose 4-epimerase
C9E88_011360	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C9E88_011365	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C9E88_011370	ENOG4105CC0	LysR family Transcriptional regulator
C9E88_011375	ENOG4108MXF	Alpha Beta Hydrolase
C9E88_011385	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9E88_011400	ENOG4105F27	Major Facilitator
C9E88_011405	ENOG4105CV8	reductase
C9E88_011410	ENOG4105HEI	LysR family (Transcriptional regulator
C9E88_011430	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C9E88_011435	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C9E88_011445	ENOG4105CNI	cell division protein FtsW
C9E88_011470	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C9E88_011475	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C9E88_011490	ENOG4105K59	histidine triad (HIT) protein
C9E88_011510	ENOG4105C28	cystathionine
C9E88_011520	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C9E88_011555	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C9E88_011565	ENOG41080XP	Cbs domain
C9E88_011600	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C9E88_011615	ENOG41068P6	UPF0319 protein
C9E88_011645	ENOG4105BZU	Histidine kinase
C9E88_011660	ENOG4105D8G	Major Facilitator superfamily
C9E88_011665	ENOG4105BZU	Histidine kinase
C9E88_011675	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C9E88_011680	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C9E88_011725	ENOG4105EV9	Alpha Beta Hydrolase
C9E88_011755	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9E88_011810	ENOG4105EIY	sodium-type flagellar protein motY
C9E88_011840	ENOG410630P	Transcriptional regulator
C9E88_011860	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
C9E88_011895	ENOG4105CHR	reductase
C9E88_011955	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_011960	ENOG4105C26	Dehydrogenase
C9E88_011970	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C9E88_011975	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C9E88_011980	ENOG4105E0C	molybdate abc transporter
C9E88_011985	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C9E88_011990	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C9E88_011995	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C9E88_012025	ENOG4108IFG	nitrite reductase, (NAD(P)H)
C9E88_012030	ENOG4107QZF	nitrite reductase NADPH large subunit
C9E88_012035	ENOG4107RNU	major facilitator superfamily MFS_1
C9E88_012050	ENOG4105DUM	transcriptional regulator, lysR family
C9E88_012055	ENOG41061H0	Monooxygenase
C9E88_012060	ENOG4105DHG	Allantoate amidinohydrolase
C9E88_012070	ENOG4105C2W	permease
C9E88_012090	ENOG4105CMU	LysR family (Transcriptional regulator
C9E88_012100	ENOG41067MG	lrgb family
C9E88_012105	ENOG4105RPH	Inner membrane protein YddG
C9E88_012110	ENOG4107R1I	NAD-dependent malic enzyme
C9E88_012150	ENOG4105CEY	Amp-dependent synthetase and ligase
C9E88_012160	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C9E88_012170	ENOG4105D2S	major facilitator superfamily
C9E88_012175	ENOG4108KB2	LysR family Transcriptional regulator
C9E88_012180	ENOG4105DTQ	mandelate racemase muconate lactonizing
C9E88_012185	ENOG4105NN7	muconolactone delta-isomerase
C9E88_012195	ENOG4105FUY	alpha subunit
C9E88_012200	ENOG4108UKV	benzoate 1,2-dioxygenase
C9E88_012205	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
C9E88_012210	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
C9E88_012215	ENOG4105DKK	Benzoate
C9E88_012220	ENOG4107QP7	CoA-transferase subunit A
C9E88_012225	ENOG4107QNJ	CoA-transferase subunit B
C9E88_012230	ENOG4105CHU	acetyl-coa acetyltransferase
C9E88_012235	ENOG4105F2Z	3-oxoadipate enol-lactonase
C9E88_012240	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C9E88_012255	ENOG4108JQ9	ABC transporter
C9E88_012275	ENOG4108Z6B	deaminase
C9E88_012285	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C9E88_012295	ENOG4107RGD	Major Facilitator superfamily
C9E88_012310	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C9E88_012340	ENOG4105HF0	Membrane
C9E88_012345	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
C9E88_012365	ENOG41062ES	Transcriptional regulator
C9E88_012380	ENOG4108HW3	(ABC) transporter
C9E88_012390	ENOG4105MRR	Transcriptional regulator (By similarity)
C9E88_012400	ENOG4108RCM	Nitroreductase
C9E88_012410	ENOG4105KVH	Transcriptional regulator
C9E88_012445	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C9E88_012460	ENOG4105E2B	Taurine dioxygenase
C9E88_012465	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C9E88_012470	ENOG4108IY8	ABC, transporter
C9E88_012475	ENOG4106FTQ	Taurine ABC transporter, periplasmic
C9E88_012500	ENOG4105CYC	Transferase
C9E88_012505	ENOG4105CHU	acetyl-coa acetyltransferase
C9E88_012510	ENOG4105CSU	acyl-Coa dehydrogenase
C9E88_012515	ENOG41062JF	Transcriptional regulator
C9E88_012535	ENOG4105C6T	cysteine synthase
C9E88_012540	ENOG41080HT	Transcriptional regulator, arsr family
C9E88_012560	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
C9E88_012570	ENOG4105BZ1	(ABC) transporter
C9E88_012580	ENOG4108ZX5	transcriptional regulator
C9E88_012590	ENOG4105CZX	twitching motility protein
C9E88_012595	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C9E88_012615	ENOG4107RZC	phospholipase d
C9E88_012635	ENOG4105T38	integral membrane protein
C9E88_012680	ENOG4105C1G	acyl-Coa dehydrogenase
C9E88_012685	ENOG41064T2	transcriptional regulator, lysR family
C9E88_012690	ENOG4105KK6	nuclease
C9E88_012700	ENOG4105CZM	Major Facilitator
C9E88_012750	ENOG4105CPW	cytochrome b561
C9E88_012865	ENOG4105Y5J	prophage protein
C9E88_012925	ENOG4105VEQ	Cold shock protein
C9E88_012935	ENOG4105VEQ	Cold shock protein
C9E88_013005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C9E88_013030	ENOG4105W7J	DNA binding
C9E88_013035	ENOG4105RDA	repressor
C9E88_013080	ENOG4108I1J	Integrase
C9E88_013100	ENOG4107QIJ	Aconitate hydratase 2
C9E88_013130	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C9E88_013155	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C9E88_013180	ENOG4105CFU	surface antigen
C9E88_013185	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
C9E88_013205	ENOG4107ZVW	dihydroneopterin aldolase
C9E88_013215	ENOG4105D06	uba thif-type nad fad binding protein
C9E88_013220	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
C9E88_013225	ENOG4105C2C	drug resistance transporter, Bcr CflA
C9E88_013235	ENOG4105C1G	acyl-Coa dehydrogenase
C9E88_013255	ENOG4105GVF	(ABC) transporter
C9E88_013260	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C9E88_013265	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C9E88_013270	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C9E88_013290	ENOG4105DEN	Luciferase family
C9E88_013315	ENOG4105E2S	oxidase) subunit II
C9E88_013320	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C9E88_013325	ENOG4105CCU	oxidase (Subunit III)
C9E88_013330	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C9E88_013365	ENOG4105CDU	Replicative dna helicase
C9E88_013370	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C9E88_013405	ENOG4105CBC	glutamate synthase
C9E88_013425	ENOG4105KJF	protein tyrosine phosphatase
C9E88_013430	ENOG4105C0A	alcohol dehydrogenase
C9E88_013445	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C9E88_013470	ENOG4105CHR	reductase
C9E88_013475	ENOG4105CHU	acetyl-coa acetyltransferase
C9E88_013485	ENOG4105DUM	transcriptional regulator, lysR family
C9E88_013490	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C9E88_013495	ENOG4108NIW	Leucine export protein LeuE
C9E88_013500	ENOG4108IG5	Transcriptional regulator
C9E88_013515	ENOG41081QV	Universal stress protein
C9E88_013535	ENOG4105CD8	aminopeptidase N
C9E88_013565	ENOG4105EE5	Membrane protein terC
C9E88_013595	ENOG4107QP3	malate synthase g
C9E88_013600	ENOG4105D6Z	AFG1 family ATPase
C9E88_013610	ENOG4107RN6	Monooxygenase
C9E88_013615	ENOG4105DWU	Membrane
C9E88_013635	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C9E88_013640	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C9E88_013655	ENOG4108Z6B	deaminase
C9E88_013665	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C9E88_013675	ENOG4108RTD	type II secretion system protein K
C9E88_013700	ENOG4105F8V	Hydrolase, tatD family
C9E88_013710	ENOG4107QRG	dna polymerase iii
C9E88_013720	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C9E88_013725	ENOG4105BZ1	(ABC) transporter
C9E88_013740	ENOG4105FA0	parb-like partition protein
C9E88_013745	ENOG4107QJE	Chromosome Partitioning Protein
C9E88_013755	ENOG4108S0S	Nucleotidyl transferase
C9E88_013760	ENOG4105EHM	Aminoglycoside phosphotransferase
C9E88_013765	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C9E88_013770	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C9E88_013775	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C9E88_013780	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C9E88_013785	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C9E88_013790	ENOG4105K8N	protein family UPF0079, ATPase
C9E88_013795	ENOG4105DR9	pseudouridine synthase
C9E88_013810	ENOG4105I08	Pseudouridine synthase
C9E88_013815	ENOG4108VMM	UPF0756 membrane protein
C9E88_013830	ENOG4107QUV	Domain protein
C9E88_013850	ENOG4105CQ7	ATP-dependent helicase
C9E88_013855	ENOG4105D3R	alkyl hydroperoxide reductase
C9E88_013875	ENOG4108JU3	Alkyl hydroperoxide reductase
C9E88_013890	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
C9E88_013905	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
C9E88_013910	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C9E88_013915	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C9E88_013940	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C9E88_013985	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
C9E88_014010	ENOG4107T8P	acyl-Coa dehydrogenase
C9E88_014035	ENOG4108UMI	ABC transporter, permease
C9E88_014040	ENOG4105C3G	gtp-binding protein
C9E88_014070	ENOG4108UMN	azlc family
C9E88_014105	ENOG4108V06	Glutathione peroxidase
C9E88_014115	ENOG4105CHM	Aminotransferase
C9E88_014120	ENOG4108R99	pseudouridine synthase
C9E88_014135	ENOG4105DZ1	carboxypeptidase
C9E88_014140	ENOG4105CEP	NADH dehydrogenase
C9E88_014145	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C9E88_014160	ENOG4105ERG	peptidase m48, ste24p
C9E88_014165	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C9E88_014180	ENOG4108UMN	azlc family
C9E88_014195	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C9E88_014200	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C9E88_014205	ENOG4105CFH	Aspartokinase
C9E88_014215	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C9E88_014250	ENOG4105C7N	Xanthine uracil vitamin C permease
C9E88_014275	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C9E88_014280	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C9E88_014285	ENOG4105CQC	Prephenate dehydratase
C9E88_014290	ENOG4107R7Y	intracellular protease Pfpi family
C9E88_014300	ENOG4105CK2	sodium dicarboxylate symporter
C9E88_014305	ENOG4107QYG	anthranilate phosphoribosyltransferase
C9E88_014310	ENOG4105VUT	cytoplasmic protein
C9E88_014315	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C9E88_014320	ENOG4105BZ4	penicillin-binding protein
C9E88_014330	ENOG4105M6F	mutator MutT protein
C9E88_014340	ENOG4105DHQ	Histidine kinase
C9E88_014345	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C9E88_014355	ENOG4107QHF	type ii secretion system protein e
C9E88_014365	ENOG4108R96	Methyltransferase, YaeB family
C9E88_014370	ENOG4105DP0	ferredoxin-NADP reductase
C9E88_014405	ENOG4105CS6	Rhs element vgr protein
C9E88_014420	ENOG4105CAU	Arsenical resistance protein, ArsH
C9E88_014425	ENOG4105D6J	arsenicaL-resistance protein
C9E88_014430	ENOG4107WAU	Protein tyrosine phosphatase
C9E88_014435	ENOG41082YX	Transcriptional regulator, arsr family
C9E88_014440	ENOG4105CFP	Peptidase U32
C9E88_014445	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C9E88_014450	ENOG4108JU3	Alkyl hydroperoxide reductase
C9E88_014475	ENOG4105NXH	GreA GreB family elongation factor
C9E88_014510	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C9E88_014515	ENOG4107R3N	Filamentation induced by cAMP protein fic
C9E88_014525	ENOG4105CAU	Arsenical resistance protein, ArsH
C9E88_014530	ENOG4105D6J	arsenicaL-resistance protein
C9E88_014540	ENOG41082YX	Transcriptional regulator, arsr family
C9E88_014570	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C9E88_014595	ENOG41080HT	Transcriptional regulator, arsr family
C9E88_014600	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C9E88_014610	ENOG410624X	efflux transporter, rnd family, mfp subunit
C9E88_014615	ENOG4107R3N	Filamentation induced by cAMP protein fic
C9E88_014650	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C9E88_014655	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C9E88_014685	ENOG4107R3N	Filamentation induced by cAMP protein fic
C9E88_014745	ENOG4105DFP	Integrase
C9E88_014755	ENOG4105DA5	(ABC) transporter
C9E88_014760	ENOG4105E3A	(ABC) transporter
C9E88_014780	ENOG4105CVE	Lytic murein transglycosylase
C9E88_014820	ENOG4105CE9	30S ribosomal protein S2
C9E88_014825	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C9E88_014830	ENOG4105CHM	Aminotransferase
C9E88_014855	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
C9E88_014860	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C9E88_014865	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C9E88_014875	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C9E88_014880	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C9E88_014890	ENOG4105C3F	Signal peptidase i
C9E88_014905	ENOG4105C0H	protease
C9E88_014910	ENOG4108IYU	L-aspartate oxidase
C9E88_014935	ENOG4105HHA	aminodeoxychorismate lyase
C9E88_014940	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
C9E88_014945	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C9E88_014950	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C9E88_014960	ENOG4108I5D	sulfate abc transporter
C9E88_014965	ENOG4105ECW	sulfate abc transporter
C9E88_014970	ENOG4108IJ6	ABC transporter
C9E88_014975	ENOG4107R11	Transcriptional regulator
C9E88_014995	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C9E88_015000	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C9E88_015010	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9E88_015020	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C9E88_015025	ENOG4108YYC	ycei family
C9E88_015045	ENOG4105EGD	dinuclear metal center protein, YbgI family
C9E88_015070	ENOG4108ETH	Formylglycinamide ribotide synthetase
C9E88_015080	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C9E88_015100	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C9E88_015110	ENOG4107YD3	Thioesterase
C9E88_015115	ENOG4105E02	MotA TolQ exbB proton channel
C9E88_015120	ENOG4105M8F	Biopolymer transport protein exbD tolR
C9E88_015130	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C9E88_015135	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C9E88_015185	ENOG4105C02	permease
C9E88_015190	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C9E88_015195	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C9E88_015215	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
C9E88_015220	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C9E88_015225	ENOG4105D60	lipoprotein releasing system transmembrane protein
C9E88_015240	ENOG4108UPT	UPF0178 protein
C9E88_015260	ENOG4107KET	secretion protein, HlyD family
C9E88_015275	ENOG4105CK2	sodium dicarboxylate symporter
C9E88_015290	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9E88_015295	ENOG4105C10	Electron transfer flavoprotein
C9E88_015300	ENOG4105BZJ	Electron transfer flavoprotein
C9E88_015305	ENOG4105N14	lysine exporter protein LysE YggA
C9E88_015310	ENOG4108YXU	transcriptional regulator AsnC family
C9E88_015325	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C9E88_015340	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C9E88_015370	ENOG4105E4C	Lytic transglycosylase catalytic
C9E88_015385	ENOG4105E4C	Lytic transglycosylase catalytic
C9E88_015450	ENOG4107QJE	Chromosome Partitioning Protein
C9E88_015550	ENOG4105F9F	transposase
C9E88_015565	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C9E88_015570	ENOG4105EPC	oxidoreductase
C9E88_015575	ENOG4105VF7	tolerance protein
C9E88_015580	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C9E88_015605	ENOG4105F9F	transposase
C9E88_015625	ENOG4105KK6	nuclease
C9E88_015640	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C9E88_015650	ENOG4105JQZ	Methyltransferase
C9E88_015675	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C9E88_015685	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C9E88_015700	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C9E88_015705	ENOG4105C34	Pseudouridine synthase
C9E88_015710	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9E88_015715	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C9E88_015730	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
C9E88_015760	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C9E88_015765	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C9E88_015790	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C9E88_015820	ENOG4107T5V	SNARE associated Golgi
C9E88_015840	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C9E88_015850	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C9E88_015865	ENOG4105CUB	amino acid
C9E88_015875	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C9E88_015880	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C9E88_015885	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C9E88_015895	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C9E88_015900	ENOG4105K46	50S ribosomal protein l27
C9E88_015905	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C9E88_015920	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C9E88_015925	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C9E88_015930	ENOG4105BZS	acriflavin resistance protein
C9E88_015935	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C9E88_015940	ENOG4105K8R	UPF0145 protein
C9E88_015945	ENOG41083I7	UPF0145 protein
C9E88_015965	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C9E88_015970	ENOG4107RRE	RNA-directed DNA polymerase
C9E88_015990	ENOG4105BZU	Histidine kinase
C9E88_015995	ENOG4107RP9	extracellular solute-binding protein, family 3
C9E88_016000	ENOG4105EAD	ABC transporter
C9E88_016005	ENOG4105DRP	amino acid AbC transporter
C9E88_016010	ENOG4105CDA	abc transporter atp-binding protein
C9E88_016030	ENOG4105DHQ	Histidine kinase
C9E88_016035	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C9E88_016040	ENOG4105DIJ	Phosphoethanolamine transferase
C9E88_016055	ENOG4105D78	K07001 NTE family protein
C9E88_016070	ENOG4105CK7	Sodium proline symporter
C9E88_016075	ENOG4105CTB	Polyprenyl synthetase
C9E88_016080	ENOG4105C7F	AcnD-accessory protein PrpF
C9E88_016085	ENOG4105C85	amino acid
C9E88_016110	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
C9E88_016120	ENOG4105D8T	Acyltransferase
C9E88_016125	ENOG4105C03	ribonuclease
C9E88_016130	ENOG4108Z03	MAF-like protein
C9E88_016135	ENOG4105VQ7	Rod shape-determining protein MreD
C9E88_016140	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C9E88_016145	ENOG4105DFF	Rod shape-determining protein mreb
C9E88_016150	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C9E88_016160	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C9E88_016230	ENOG4105BZG	amino acid carrier protein
C9E88_016240	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C9E88_016250	ENOG41082ND	Uncharacterized protein yjcO
C9E88_016265	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C9E88_016270	ENOG4105SYT	Methylenetetrahydrofolate reductase
C9E88_016275	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C9E88_016285	ENOG4105C6K	Malic enzyme
C9E88_016300	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
C9E88_016310	ENOG4105MP9	class II Aldolase
C9E88_016325	ENOG4108RRZ	Transcription elongation factor GreB
C9E88_016330	ENOG4105DZ2	Transcriptional regulator
C9E88_016340	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
C9E88_016350	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C9E88_016355	ENOG4105E4C	Lytic transglycosylase catalytic
C9E88_016360	ENOG4105D0M	Protease HtpX homolog
C9E88_016370	ENOG4105CJW	magnesium transporter
C9E88_016375	ENOG4105BZS	acriflavin resistance protein
C9E88_016390	ENOG41080IJ	Diacylglycerol kinase
C9E88_016395	ENOG4107RET	Isocitrate lyase
C9E88_016405	ENOG4105C37	(CBS) domain
C9E88_016415	ENOG4105D4T	Citrate transporter
C9E88_016445	ENOG4105EEI	dihydropteroate synthase
C9E88_016450	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C9E88_016460	ENOG4105HBR	Rna-binding protein
C9E88_016475	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C9E88_016485	ENOG4108R0M	Aminoglycoside
C9E88_016500	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
C9E88_016595	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C9E88_016600	ENOG4108F3G	Type I restriction-modification system, R subunit
C9E88_016610	ENOG4107QJE	Chromosome Partitioning Protein
C9E88_016615	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C9E88_016630	ENOG41090JH	(ATPase)-like protein
C9E88_016725	ENOG4106PHI	plasmid recombination enzyme