locus-tag	class	description
MST18_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MST18_00010	COG0592	DNA-directed DNA polymerase activity
MST18_00020	COG0187	DNA topoisomerase II activity
MST18_00030	COG0488	(ABC) transporter
MST18_00085	COG0657	acetylesterase activity
MST18_00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MST18_00125	COG2814	Major facilitator Superfamily
MST18_00130	COG1012	belongs to the aldehyde dehydrogenase family
MST18_00135	COG3738	Protein conserved in bacteria
MST18_00140	COG0733	neurotransmitter:sodium symporter activity
MST18_00150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MST18_00150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MST18_00160	COG0129	dihydroxy-acid dehydratase activity
MST18_00165	COG0129	dihydroxy-acid dehydratase activity
MST18_00180	COG2801	Transposase and inactivated derivatives
MST18_00200	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
MST18_00205	COG2801	Transposase and inactivated derivatives
MST18_00225	COG0583	DNA-binding transcription factor activity
MST18_00230	COG2233	PERMEase
MST18_00240	COG1309	transcriptional regulator
MST18_00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST18_00265	COG3307	-O-antigen
MST18_00290	COG1064	alcohol dehydrogenase
MST18_00295	COG2818	Glycosylase
MST18_00310	COG1194	a g-specific adenine glycosylase
MST18_00350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MST18_00355	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MST18_00360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MST18_00395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MST18_00405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MST18_00415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MST18_00425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MST18_00430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MST18_00435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MST18_00450	COG1309	transcriptional regulator
MST18_00455	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_00485	COG1454	alcohol dehydrogenase
MST18_00490	COG0281	malic enzyme
MST18_00495	COG2011	ABC-type metal ion transport system permease component
MST18_00500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MST18_00540	COG0271	Belongs to the BolA IbaG family
MST18_00550	COG1192	Involved in chromosome partitioning
MST18_00565	COG0586	Pfam SNARE associated Golgi protein
MST18_00570	COG2259	Doxx family
MST18_00575	COG0519	Catalyzes the synthesis of GMP from XMP
MST18_00575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MST18_00580	COG1715	Restriction endonuclease
MST18_00585	COG3706	GGDEF domain
MST18_00650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST18_00670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST18_00675	COG3829	transcription factor binding
MST18_00690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST18_00695	COG0534	Mate efflux family protein
MST18_00700	COG0436	Aminotransferase
MST18_00725	COG2837	iron assimilation
MST18_00730	COG1280	lysine exporter protein (LysE YggA)
MST18_00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MST18_00740	COG1121	(ABC) transporter
MST18_00835	COG0386	Belongs to the glutathione peroxidase family
MST18_00855	COG0758	DNA mediated transformation
MST18_00885	COG1122	ATPase activity
MST18_00920	COG2814	Major facilitator Superfamily
MST18_00945	COG0477	Major facilitator Superfamily
MST18_00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MST18_00965	COG2814	Major facilitator Superfamily
MST18_00985	COG1253	flavin adenine dinucleotide binding
MST18_00995	COG2860	membrane
MST18_01000	COG0477	Major facilitator Superfamily
MST18_01010	COG0318	PFAM AMP-dependent synthetase and ligase
MST18_01025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MST18_01055	COG0347	Belongs to the P(II) protein family
MST18_01060	COG0004	ammonium transporteR
MST18_01070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MST18_01070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MST18_01085	COG0586	Pfam SNARE associated Golgi protein
MST18_01110	COG0795	lipopolysaccharide-transporting ATPase activity
MST18_01115	COG0795	lipopolysaccharide-transporting ATPase activity
MST18_01120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MST18_01125	COG0793	Belongs to the peptidase S41A family
MST18_01140	COG2197	response regulator
MST18_01150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MST18_01165	COG4974	Belongs to the 'phage' integrase family
MST18_01190	COG0772	Belongs to the SEDS family
MST18_01200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MST18_01205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MST18_01220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MST18_01230	COG1538	Outer membrane efflux protein
MST18_01240	COG1132	(ABC) transporter
MST18_01255	COG1289	transmembrane transporter activity
MST18_01270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MST18_01285	COG0497	DNA recombination
MST18_01290	COG3123	guanosine phosphorylase activity
MST18_01295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MST18_01305	COG0237	dephospho-CoA kinase activity
MST18_01360	COG0779	Required for maturation of 30S ribosomal subunits
MST18_01365	COG0195	Participates in both transcription termination and antitermination
MST18_01375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MST18_01395	COG1320	monovalent cation:proton antiporter activity
MST18_01400	COG2212	antiporter activity
MST18_01405	COG1863	multisubunit Na H antiporter MnhE subunit
MST18_01410	COG0651	ATP synthesis coupled electron transport
MST18_01415	COG1006	Multisubunit Na H antiporter MnhC subunit
MST18_01420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MST18_01420	COG2111	Na H antiporter
MST18_01435	COG0140	phosphoribosyl-ATP diphosphatase activity
MST18_01435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MST18_01445	COG4221	oxidoreductase activity
MST18_01455	COG0488	(ABC) transporter
MST18_01495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MST18_01515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MST18_01520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MST18_01530	COG2226	methyltransferase
MST18_01580	COG0067	glutamate synthase
MST18_01580	COG0070	glutamate synthase
MST18_01580	COG0069	glutamate synthase activity
MST18_01585	COG0493	'glutamate synthase
MST18_01595	COG1704	LemA family
MST18_01610	COG4969	Belongs to the N-Me-Phe pilin family
MST18_01640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MST18_01645	COG1758	RNA polymerase activity
MST18_01650	COG0194	GDP metabolic process
MST18_01660	COG4968	Prepilin-type N-terminal cleavage methylation domain
MST18_01670	COG4966	pilus assembly protein PilW
MST18_01695	COG0228	four-way junction DNA binding
MST18_01700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MST18_01710	COG0335	large ribosomal subunit rRNA binding
MST18_01715	COG2963	transposase activity
MST18_01725	COG4372	Transposase
MST18_01735	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MST18_01740	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MST18_01745	COG5380	lipid catabolic process
MST18_01750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MST18_01770	COG5006	permease, DMT superfamily
MST18_01775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MST18_01780	COG0277	FAD linked oxidase domain protein
MST18_01805	COG2814	Major facilitator Superfamily
MST18_01835	COG2032	superoxide dismutase activity
MST18_01840	COG0628	permease
MST18_01845	COG1192	Involved in chromosome partitioning
MST18_01860	COG2226	methyltransferase
MST18_01880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MST18_01885	COG0254	rRNA binding
MST18_01890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MST18_01905	COG0534	Mate efflux family protein
MST18_01915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MST18_01930	COG1960	acyl-CoA dehydrogenase activity
MST18_01950	COG0408	coproporphyrinogen oxidase activity
MST18_01955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MST18_01975	COG0513	Belongs to the DEAD box helicase family
MST18_01980	COG1127	ABC transporter
MST18_01985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MST18_01990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MST18_01995	COG2854	intermembrane phospholipid transfer
MST18_02005	COG0598	Magnesium transport protein CorA
MST18_02020	COG1040	competence protein
MST18_02025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MST18_02040	COG2937	Belongs to the GPAT DAPAT family
MST18_02045	COG1946	Acyl-CoA thioesterase
MST18_02050	COG1301	dicarboxylic acid transport
MST18_02070	COG1959	2 iron, 2 sulfur cluster binding
MST18_02080	COG0433	COG0433 Predicted ATPase
MST18_02085	COG0626	cystathionine gamma-synthase activity
MST18_02100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MST18_02105	COG0088	Forms part of the polypeptide exit tunnel
MST18_02120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MST18_02170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MST18_02175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MST18_02185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MST18_02210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MST18_02225	COG0202	RNA polymerase activity
MST18_02230	COG0203	ribosomal protein L17
MST18_02235	COG2072	flavoprotein involved in K transport
MST18_02245	COG1960	acyl-CoA dehydrogenase activity
MST18_02250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MST18_02275	COG0697	spore germination
MST18_02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MST18_02290	COG0339	signal peptide processing
MST18_02300	COG0557	exoribonuclease II activity
MST18_02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
MST18_02360	COG1295	ribonuclease BN
MST18_02400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MST18_02405	COG1702	phosphate starvation-inducible protein PhoH
MST18_02410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MST18_02415	COG0739	heme binding
MST18_02415	COG0741	lytic transglycosylase activity
MST18_02415	COG1196	nuclear chromosome segregation
MST18_02450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MST18_02455	COG1183	phosphatidylcholine synthase activity
MST18_02520	COG1607	acyl-coa hydrolase
MST18_02555	COG2350	Protein conserved in bacteria
MST18_02565	COG0613	PHP domain protein
MST18_02570	COG3781	membrane
MST18_02575	COG2003	Belongs to the UPF0758 family
MST18_02580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MST18_02585	COG0495	leucyl-tRNA aminoacylation
MST18_02590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MST18_02610	COG2814	Major facilitator Superfamily
MST18_02615	COG0697	spore germination
MST18_02635	COG0004	ammonium transporteR
MST18_02650	COG3622	Belongs to the hyi family
MST18_02655	COG2084	Dehydrogenase
MST18_02660	COG1024	Enoyl-CoA hydratase
MST18_02665	COG5002	protein histidine kinase activity
MST18_02665	COG2205	protein histidine kinase activity
MST18_02665	COG0784	Response regulator, receiver
MST18_02685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MST18_02705	COG1862	Preprotein translocase
MST18_02720	COG1704	LemA family
MST18_02730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MST18_02750	COG5002	protein histidine kinase activity
MST18_02755	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MST18_02770	COG2194	sulfuric ester hydrolase activity
MST18_02810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MST18_02855	COG1960	acyl-CoA dehydrogenase activity
MST18_02860	COG1960	acyl-CoA dehydrogenase activity
MST18_02870	COG2205	protein histidine kinase activity
MST18_02875	COG0745	RESPONSE REGULATOR receiver
MST18_02885	COG1113	amino acid transport
MST18_02920	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MST18_02940	COG2096	Adenosyltransferase
MST18_02945	COG4206	TonB-dependent receptor
MST18_03005	COG0285	dihydrofolate synthase activity
MST18_03025	COG0450	alkyl hydroperoxide reductase
MST18_03040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MST18_03045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MST18_03080	COG2885	chlorophyll binding
MST18_03085	COG5001	Diguanylate cyclase
MST18_03085	COG3300	MHYT domain
MST18_03140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MST18_03145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MST18_03205	COG1214	PFAM Peptidase M22, glycoprotease
MST18_03210	COG1968	undecaprenyl-diphosphatase activity
MST18_03230	COG4269	membrane
MST18_03245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MST18_03255	COG2132	Multicopper oxidase
MST18_03265	COG2076	Multidrug Resistance protein
MST18_03290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MST18_03295	COG1278	Cold shock
MST18_03305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MST18_03310	COG3545	Serine hydrolase
MST18_03325	COG0730	response to heat
MST18_03335	COG1196	nuclear chromosome segregation
MST18_03345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MST18_03350	COG0833	amino acid
MST18_03360	COG2233	PERMEase
MST18_03365	COG1217	gtp-binding protein TYPA
MST18_03380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MST18_03395	COG3659	wide pore channel activity
MST18_03400	COG4772	TonB-dependent receptor
MST18_03405	COG1902	pentaerythritol trinitrate reductase activity
MST18_03435	COG0354	folic acid binding
MST18_03440	COG2132	Multicopper oxidase
MST18_03440	COG2132	Multicopper oxidase
MST18_03460	COG4456	Virulence-associated protein
MST18_03465	COG1487	ribonuclease activity
MST18_03500	COG0564	pseudouridine synthase activity
MST18_03520	COG3189	MarR family transcriptional regulator
MST18_03525	COG2824	Alkylphosphonate utilization operon protein PhnA
MST18_03550	COG0628	permease
MST18_03555	COG5342	invasion associated locus B
MST18_03560	COG0351	phosphomethylpyrimidine kinase
MST18_03560	COG0352	thiamine-phosphate diphosphorylase activity
MST18_03560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MST18_03580	COG2314	TM2 domain
MST18_03590	COG3152	Membrane
MST18_03615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MST18_03620	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MST18_03620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MST18_03625	COG0745	RESPONSE REGULATOR receiver
MST18_03630	COG2205	protein histidine kinase activity
MST18_03640	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MST18_03650	COG0649	NAD binding
MST18_03650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MST18_03660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MST18_03675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MST18_03685	COG0713	ATP synthesis coupled electron transport
MST18_03690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MST18_03695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MST18_03705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MST18_03715	COG1278	Cold shock
MST18_03720	COG0583	DNA-binding transcription factor activity
MST18_03730	COG1126	abc transporter atp-binding protein
MST18_03735	COG0765	amino acid transport
MST18_03740	COG0765	amino acid transport
MST18_03760	COG0668	transmembrane transport
MST18_03775	COG2081	HI0933 family
MST18_03825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MST18_03825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MST18_03845	COG0489	protein tyrosine kinase activity
MST18_03860	COG2358	TRAP transporter, solute receptor (TAXI family
MST18_03895	COG0442	prolyl-tRNA aminoacylation
MST18_03930	COG0840	transmembrane signaling receptor activity
MST18_03935	COG0643	Histidine kinase
MST18_03935	COG2198	Histidine kinase
MST18_03960	COG2832	Protein of unknown function (DUF454)
MST18_04020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MST18_04030	COG1289	transmembrane transporter activity
MST18_04035	COG2814	Major facilitator Superfamily
MST18_04045	COG0786	glutamate:sodium symporter activity
MST18_04050	COG1115	amino acid carrier protein
MST18_04055	COG1752	Esterase of the alpha-beta hydrolase superfamily
MST18_04065	COG1607	acyl-coa hydrolase
MST18_04075	COG2814	Major facilitator Superfamily
MST18_04080	COG0583	DNA-binding transcription factor activity
MST18_04110	COG0523	cobalamin synthesis protein
MST18_04115	COG4681	YaeQ
MST18_04125	COG2203	Gaf domain
MST18_04125	COG2199	diguanylate cyclase activity
MST18_04150	COG1024	Enoyl-CoA hydratase
MST18_04175	COG0477	Major facilitator Superfamily
MST18_04180	COG0242	peptide deformylase activity
MST18_04195	COG2066	Belongs to the glutaminase family
MST18_04215	COG2852	Protein conserved in bacteria
MST18_04225	COG0525	valine-tRNA ligase activity
MST18_04235	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_04250	COG0393	Putative heavy-metal-binding
MST18_04255	COG1538	Outer membrane efflux protein
MST18_04265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST18_04270	COG0671	phosphoesterase, PA-phosphatase related
MST18_04285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MST18_04290	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MST18_04315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MST18_04325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MST18_04330	COG1648	precorrin-2 dehydrogenase activity
MST18_04330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MST18_04335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MST18_04370	COG0531	amino acid
MST18_04385	COG0321	lipoyl(octanoyl) transferase activity
MST18_04395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MST18_04420	COG0586	Pfam SNARE associated Golgi protein
MST18_04445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MST18_04470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MST18_04475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MST18_04505	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MST18_04520	COG0358	DNA primase activity
MST18_04530	COG0564	pseudouridine synthase activity
MST18_04560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MST18_04585	COG0110	maltose O-acetyltransferase activity
MST18_04590	COG0251	oxidation-reduction process
MST18_04595	COG1309	transcriptional regulator
MST18_04610	COG0505	Belongs to the CarA family
MST18_04635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MST18_04640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MST18_04670	COG2851	Citrate transporter
MST18_04680	COG1253	flavin adenine dinucleotide binding
MST18_04715	COG0584	glycerophosphoryl diester phosphodiesterase
MST18_04725	COG2239	Acts as a magnesium transporter
MST18_04740	COG1196	nuclear chromosome segregation
MST18_04740	COG0741	lytic transglycosylase activity
MST18_04740	COG0739	heme binding
MST18_04745	COG0037	tRNA processing
MST18_04755	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MST18_04760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MST18_04775	COG0235	Class ii aldolase
MST18_04785	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MST18_04800	COG0280	phosphate acetyltransferase
MST18_04800	COG0281	malic enzyme
MST18_04810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MST18_04815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MST18_04820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MST18_04840	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MST18_04875	COG1115	amino acid carrier protein
MST18_04880	COG1113	amino acid transport
MST18_04890	COG0019	diaminopimelate decarboxylase activity
MST18_04910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MST18_04925	COG1280	lysine exporter protein (LysE YggA)
MST18_04960	COG1301	dicarboxylic acid transport
MST18_04980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST18_05000	COG1671	Belongs to the UPF0178 family
MST18_05005	COG0697	spore germination
MST18_05020	COG1136	(ABC) transporter
MST18_05025	COG2333	competence protein COMEC
MST18_05025	COG0658	competence protein
MST18_05050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MST18_05055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MST18_05060	COG0628	permease
MST18_05095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MST18_05115	COG0823	Involved in the tonB-independent uptake of proteins
MST18_05135	COG0824	Thioesterase
MST18_05145	COG2255	four-way junction helicase activity
MST18_05165	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MST18_05165	COG0047	phosphoribosylformylglycinamidine synthase activity
MST18_05180	COG0583	DNA-binding transcription factor activity
MST18_05185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MST18_05185	COG3323	Protein of unknown function (DUF1653)
MST18_05190	COG0778	Nitroreductase
MST18_05195	COG1024	Enoyl-CoA hydratase
MST18_05200	COG1051	belongs to the nudix hydrolase family
MST18_05200	COG1056	cytidyltransferase-related domain
MST18_05205	COG2353	YceI-like domain
MST18_05210	COG0583	DNA-binding transcription factor activity
MST18_05220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MST18_05230	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MST18_05235	COG0602	queuosine metabolic process
MST18_05255	COG0583	DNA-binding transcription factor activity
MST18_05260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MST18_05265	COG4208	sulfate ABC transporter
MST18_05270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MST18_05280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MST18_05285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MST18_05290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MST18_05295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MST18_05300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MST18_05325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MST18_05340	COG0681	Belongs to the peptidase S26 family
MST18_05350	COG0571	ribonuclease III activity
MST18_05355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MST18_05365	COG1381	Involved in DNA repair and RecF pathway recombination
MST18_05370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MST18_05405	COG0436	Aminotransferase
MST18_05415	COG0052	Belongs to the universal ribosomal protein uS2 family
MST18_05440	COG2951	lytic endotransglycosylase activity
MST18_05455	COG0842	Transport permease protein
MST18_05460	COG1131	(ABC) transporter
MST18_05510	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_05525	COG2271	Major facilitator Superfamily
MST18_05540	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_05545	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MST18_05555	COG0028	Belongs to the TPP enzyme family
MST18_05560	COG1027	Aspartate ammonia-lyase
MST18_05575	COG1741	Belongs to the pirin family
MST18_05590	COG3739	integral membrane protein
MST18_05605	COG3706	GGDEF domain
MST18_05625	COG0302	gtp cyclohydrolase
MST18_05645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MST18_05650	COG0512	Glutamine amidotransferase of anthranilate synthase
MST18_05655	COG0174	glutamine synthetase
MST18_05670	COG3161	chorismate lyase activity
MST18_05675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MST18_05725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MST18_05735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MST18_05755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MST18_05765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MST18_05790	COG2175	clavaminate synthase activity
MST18_05810	COG2199	diguanylate cyclase activity
MST18_05820	COG0556	nucleotide-excision repair
MST18_05865	COG0702	epimerase
MST18_05870	COG1733	regulation of RNA biosynthetic process
MST18_05890	COG0431	NADPH-dependent FMN reductase
MST18_05895	COG0798	PFAM Bile acid sodium symporter
MST18_05905	COG0640	Transcriptional regulator
MST18_05910	COG4772	TonB-dependent receptor
MST18_05920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MST18_05925	COG0076	glutamate decarboxylase activity
MST18_05935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MST18_05940	COG0573	inorganic phosphate transmembrane transporter activity
MST18_05950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MST18_05955	COG0616	signal peptide processing
MST18_05985	COG0482	sulfurtransferase activity
MST18_06000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MST18_06005	COG1686	Belongs to the peptidase S11 family
MST18_06030	COG0583	DNA-binding transcription factor activity
MST18_06035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MST18_06040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MST18_06045	COG1067	ATP-dependent peptidase activity
MST18_06095	COG1966	Carbon starvation protein
MST18_06100	COG2879	small protein
MST18_06105	COG0714	Associated with various cellular activities
MST18_06130	COG1765	OsmC-like protein
MST18_06140	COG0667	Aldo Keto reductase
MST18_06145	COG0542	response to heat
MST18_06185	COG0540	Belongs to the ATCase OTCase family
MST18_06205	COG0589	response to stress
MST18_06210	COG0589	response to stress
MST18_06220	COG2076	Multidrug Resistance protein
MST18_06225	COG1309	transcriptional regulator
MST18_06230	COG3135	benzoate transporter
MST18_06240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MST18_06245	COG0583	DNA-binding transcription factor activity
MST18_06265	COG0183	Belongs to the thiolase family
MST18_06270	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_06280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MST18_06290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MST18_06295	COG0824	Thioesterase
MST18_06300	COG1454	alcohol dehydrogenase
MST18_06305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MST18_06325	COG0069	glutamate synthase activity
MST18_06335	COG2308	Evidence 4 Homologs of previously reported genes of
MST18_06345	COG1305	Transglutaminase-like
MST18_06355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MST18_06360	COG0305	Participates in initiation and elongation during chromosome replication
MST18_06375	COG0360	Binds together with S18 to 16S ribosomal RNA
MST18_06385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MST18_06390	COG1845	cytochrome c oxidase, subunit III
MST18_06395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MST18_06400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MST18_06425	COG4682	membrane
MST18_06430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST18_06445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MST18_06450	COG2890	protein-(glutamine-N5) methyltransferase activity
MST18_06455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST18_06460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST18_06470	COG2207	Transcriptional regulator
MST18_06480	COG1960	acyl-CoA dehydrogenase activity
MST18_06485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MST18_06495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MST18_06505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MST18_06515	COG0586	Pfam SNARE associated Golgi protein
MST18_06530	COG0477	Major facilitator Superfamily
MST18_06535	COG0729	surface antigen
MST18_06550	COG1570	exodeoxyribonuclease VII activity
MST18_06555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MST18_06595	COG0786	glutamate:sodium symporter activity
MST18_06635	COG1114	Component of the transport system for branched-chain amino acids
MST18_06640	COG0024	Methionine aminopeptidase
MST18_06645	COG0583	DNA-binding transcription factor activity
MST18_06650	COG0583	DNA-binding transcription factor activity
MST18_06655	COG2267	carboxylic ester hydrolase activity
MST18_06665	COG0446	pyridine nucleotide-disulphide oxidoreductase
MST18_06665	COG1902	pentaerythritol trinitrate reductase activity
MST18_06680	COG2814	Major facilitator Superfamily
MST18_06690	COG0583	DNA-binding transcription factor activity
MST18_06710	COG0148	phosphopyruvate hydratase activity
MST18_06725	COG0772	Belongs to the SEDS family
MST18_06740	COG4890	Cyd operon protein YbgT
MST18_06745	COG1294	oxidase, subunit
MST18_06795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MST18_06815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MST18_06830	COG0133	tryptophan synthase activity
MST18_06840	COG0516	GMP reductase activity
MST18_06840	COG0517	IMP dehydrogenase activity
MST18_06875	COG0552	protein localization to endoplasmic reticulum
MST18_06955	COG1960	acyl-CoA dehydrogenase activity
MST18_07020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MST18_07025	COG0730	response to heat
MST18_07030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MST18_07035	COG2207	Transcriptional regulator
MST18_07040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MST18_07045	COG4589	Belongs to the CDS family
MST18_07060	COG2453	phosphatase
MST18_07060	COG0671	phosphoesterase, PA-phosphatase related
MST18_07065	COG2267	carboxylic ester hydrolase activity
MST18_07070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MST18_07075	COG1946	Acyl-CoA thioesterase
MST18_07130	COG2223	nitrite transmembrane transporter activity
MST18_07145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MST18_07160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MST18_07185	COG0583	DNA-binding transcription factor activity
MST18_07210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MST18_07215	COG0671	phosphoesterase, PA-phosphatase related
MST18_07220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MST18_07240	COG1960	acyl-CoA dehydrogenase activity
MST18_07245	COG2207	Transcriptional regulator
MST18_07245	COG1917	Cupin 2, conserved barrel domain protein
MST18_07250	COG2814	Major facilitator Superfamily
MST18_07260	COG3152	Membrane
MST18_07275	COG1960	acyl-CoA dehydrogenase activity
MST18_07325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MST18_07335	COG1017	nitric oxide dioxygenase activity
MST18_07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MST18_07345	COG0488	(ABC) transporter
MST18_07350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MST18_07360	COG0509	glycine decarboxylation via glycine cleavage system
MST18_07375	COG1132	(ABC) transporter
MST18_07380	COG3706	GGDEF domain
MST18_07385	COG0668	transmembrane transport
MST18_07390	COG3122	Protein conserved in bacteria
MST18_07415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MST18_07425	COG0789	Transcriptional regulator
MST18_07440	COG1960	acyl-CoA dehydrogenase activity
MST18_07445	COG0183	Belongs to the thiolase family
MST18_07450	COG0427	acetyl-CoA hydrolase
MST18_07460	COG0546	phosphoglycolate phosphatase activity
MST18_07470	COG4521	taurine ABC transporter
MST18_07475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MST18_07480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST18_07485	COG2175	clavaminate synthase activity
MST18_07500	COG0439	Biotin carboxylase
MST18_07520	COG0864	Transcriptional regulator
MST18_07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MST18_07545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MST18_07550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MST18_07555	COG0730	response to heat
MST18_07585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MST18_07595	COG1960	acyl-CoA dehydrogenase activity
MST18_07600	COG2814	Major facilitator Superfamily
MST18_07610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MST18_07615	COG0183	Belongs to the thiolase family
MST18_07620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MST18_07625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MST18_07630	COG4829	muconolactone delta-isomerase
MST18_07635	COG4948	Mandelate Racemase Muconate Lactonizing
MST18_07640	COG0583	DNA-binding transcription factor activity
MST18_07645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST18_07645	COG1116	anion transmembrane transporter activity
MST18_07650	COG0745	RESPONSE REGULATOR receiver
MST18_07655	COG2223	nitrite transmembrane transporter activity
MST18_07660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST18_07665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST18_07670	COG0243	molybdopterin cofactor binding
MST18_07680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MST18_07695	COG0315	cyclic pyranopterin monophosphate synthase activity
MST18_07695	COG0521	Mo-molybdopterin cofactor biosynthetic process
MST18_07700	COG0303	'Molybdopterin
MST18_07705	COG0725	ABC transporter, periplasmic molybdate-binding protein
MST18_07710	COG4149	molybdate abc transporter
MST18_07715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MST18_07740	COG4628	conserved protein (DUF2132)
MST18_07755	COG0477	Major facilitator Superfamily
MST18_07760	COG1012	belongs to the aldehyde dehydrogenase family
MST18_07760	COG2030	dehydratase
MST18_07765	COG3396	Phenylacetate-CoA oxygenase
MST18_07770	COG3460	Phenylacetate-CoA oxygenase
MST18_07775	COG3396	Phenylacetate-CoA oxygenase
MST18_07780	COG2151	metal-sulfur cluster biosynthetic enzyme
MST18_07785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MST18_07790	COG1024	Enoyl-CoA hydratase
MST18_07795	COG1024	Enoyl-CoA hydratase
MST18_07800	COG1250	3-hydroxyacyl-CoA dehydrogenase
MST18_07805	COG0183	Belongs to the thiolase family
MST18_07810	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MST18_07815	COG3327	negative regulation of DNA-templated transcription, initiation
MST18_07830	COG1968	undecaprenyl-diphosphatase activity
MST18_07835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MST18_07840	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MST18_07850	COG2205	protein histidine kinase activity
MST18_07865	COG0477	Major facilitator Superfamily
MST18_07875	COG1024	Enoyl-CoA hydratase
MST18_07880	COG1960	acyl-CoA dehydrogenase activity
MST18_07885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MST18_07900	COG0583	DNA-binding transcription factor activity
MST18_07915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MST18_07935	COG2814	Major facilitator Superfamily
MST18_07940	COG0583	DNA-binding transcription factor activity
MST18_07950	COG4372	Transposase
MST18_07960	COG2963	transposase activity
MST18_07970	COG4638	Rieske (2fe-2S)
MST18_07975	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MST18_07980	COG0543	2 iron, 2 sulfur cluster binding
MST18_07980	COG0633	Ferredoxin
MST18_07985	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_07990	COG3135	benzoate transporter
MST18_07995	COG0583	DNA-binding transcription factor activity
MST18_08015	COG0583	DNA-binding transcription factor activity
MST18_08020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MST18_08025	COG4266	Belongs to the allantoicase family
MST18_08035	COG2233	PERMEase
MST18_08040	COG2351	hydroxyisourate hydrolase activity
MST18_08070	COG0697	spore germination
MST18_08085	COG0318	PFAM AMP-dependent synthetase and ligase
MST18_08175	COG0596	Alpha beta hydrolase
MST18_08220	COG0439	Biotin carboxylase
MST18_08235	COG2814	Major facilitator Superfamily
MST18_08245	COG1546	Belongs to the CinA family
MST18_08245	COG1058	Belongs to the CinA family
MST18_08260	COG2323	membrane
MST18_08270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MST18_08315	COG1278	Cold shock
MST18_08325	COG1278	Cold shock
MST18_08360	COG0372	Belongs to the citrate synthase family
MST18_08390	COG0542	response to heat
MST18_08395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MST18_08420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MST18_08425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MST18_08430	COG0569	domain protein
MST18_08435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MST18_08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MST18_08470	COG1585	Membrane protein implicated in regulation of membrane protease activity
MST18_08495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MST18_08525	COG0822	iron-sulfur transferase activity
MST18_08530	COG0316	Belongs to the HesB IscA family
MST18_08560	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MST18_08570	COG1027	Aspartate ammonia-lyase
MST18_08575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MST18_08585	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MST18_08585	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MST18_08585	COG0506	proline dehydrogenase activity
MST18_08605	COG3698	Phosphodiester glycosidase
MST18_08620	COG0667	Aldo Keto reductase
MST18_08625	COG0583	DNA-binding transcription factor activity
MST18_08630	COG3781	membrane
MST18_08695	COG0697	spore germination
MST18_08710	COG0126	phosphoglycerate kinase activity
MST18_08720	COG0424	maF-like protein
MST18_08730	COG2850	peptidyl-arginine hydroxylation
MST18_08740	COG4585	Histidine kinase
MST18_08745	COG2197	response regulator
MST18_08755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MST18_08760	COG0702	epimerase
MST18_08790	COG1011	Hydrolase
MST18_08795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MST18_08805	COG2137	regulation of response to DNA damage stimulus
MST18_08820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MST18_08830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MST18_08855	COG0575	Belongs to the CDS family
MST18_08860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MST18_08880	COG3852	Histidine kinase
MST18_08895	COG2814	Major facilitator Superfamily
MST18_08930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MST18_08935	COG0138	bifunctional purine biosynthesis protein purh
MST18_08960	COG1464	Belongs to the NlpA lipoprotein family
MST18_08965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MST18_08970	COG2011	ABC-type metal ion transport system permease component
MST18_09020	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MST18_09030	COG4122	O-methyltransferase activity
MST18_09055	COG2274	protein secretion by the type I secretion system
MST18_09065	COG1137	ATPase activity
MST18_09070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MST18_09080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MST18_09085	COG0517	IMP dehydrogenase activity
MST18_09085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MST18_09110	COG0519	Catalyzes the synthesis of GMP from XMP
MST18_09110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MST18_09115	COG1280	lysine exporter protein (LysE YggA)
MST18_09140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MST18_09150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MST18_09170	COG2391	methyltransferase activity
MST18_09305	COG0352	thiamine-phosphate diphosphorylase activity
MST18_09325	COG1309	transcriptional regulator
MST18_09350	COG0612	Peptidase, M16
MST18_09355	COG0384	phenazine biosynthesis protein PhzF
MST18_09360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MST18_09415	COG0154	amidase activity
MST18_09420	COG0477	Major facilitator Superfamily
MST18_09425	COG1522	sequence-specific DNA binding
MST18_09440	COG1610	YqeY-like protein
MST18_09485	COG0167	dihydroorotate dehydrogenase activity
MST18_09510	COG0778	Nitroreductase
MST18_09520	COG0513	Belongs to the DEAD box helicase family
MST18_09525	COG1278	Cold shock
MST18_09540	COG2363	Small membrane protein
MST18_09560	COG0625	glutathione transferase activity
MST18_09565	COG0659	secondary active sulfate transmembrane transporter activity
MST18_09570	COG4585	Histidine kinase
MST18_09575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MST18_09600	COG0308	aminopeptidase N
MST18_09635	COG1253	flavin adenine dinucleotide binding
MST18_09665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MST18_09670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MST18_09685	COG2431	L-lysine efflux transmembrane transporter activity
MST18_09700	COG0776	regulation of translation
MST18_09730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MST18_09765	COG0084	hydrolase, TatD family'
MST18_09785	COG1663	tetraacyldisaccharide 4'-kinase activity
MST18_09790	COG1132	(ABC) transporter
MST18_09800	COG0811	peptide transport
MST18_09805	COG1475	DNA binding
MST18_09810	COG1192	Involved in chromosome partitioning
MST18_09820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MST18_09825	COG3178	'Phosphotransferase
MST18_09835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MST18_09840	COG1923	regulation of RNA biosynthetic process
MST18_09850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MST18_09855	COG0802	atpase or kinase
MST18_09880	COG2707	UPF0756 membrane protein
MST18_09900	COG0583	DNA-binding transcription factor activity
MST18_09905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MST18_09925	COG1643	Atp-dependent helicase
MST18_09960	COG3634	alkyl hydroperoxide reductase activity
MST18_09975	COG1280	lysine exporter protein (LysE YggA)
MST18_09990	COG1254	Belongs to the acylphosphatase family
MST18_09995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MST18_09995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MST18_10000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MST18_10015	COG1944	ATP diphosphatase activity
MST18_10070	COG0012	GTP binding
MST18_10100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MST18_10135	COG0386	Belongs to the glutathione peroxidase family
MST18_10140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MST18_10145	COG0436	Aminotransferase
MST18_10165	COG1187	pseudouridine synthase activity
MST18_10190	COG1686	Belongs to the peptidase S11 family
MST18_10195	COG1252	NADH dehydrogenase
MST18_10215	COG0501	Belongs to the peptidase M48B family
MST18_10220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MST18_10235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MST18_10250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MST18_10255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MST18_10260	COG0527	aspartate kinase activity
MST18_10270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MST18_10280	COG3038	cytochrome b561
MST18_10290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MST18_10295	COG2252	PERMEase
MST18_10320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MST18_10325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MST18_10335	COG0693	protein deglycase activity
MST18_10340	COG1960	acyl-CoA dehydrogenase activity
MST18_10345	COG1301	dicarboxylic acid transport
MST18_10350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MST18_10355	COG3139	Protein of unknown function (DUF1315)
MST18_10360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MST18_10365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MST18_10375	COG0494	nUDIX hydrolase
MST18_10385	COG0642	Histidine kinase
MST18_10400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MST18_10420	COG1720	tRNA m6t6A37 methyltransferase activity
MST18_10475	COG0789	Transcriptional regulator
MST18_10480	COG0826	peptidase U32
MST18_10485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MST18_10490	COG3634	alkyl hydroperoxide reductase activity
MST18_10515	COG2862	Uncharacterized protein family, UPF0114
MST18_10525	COG2175	clavaminate synthase activity
MST18_10530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MST18_10570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MST18_10575	COG0010	Belongs to the arginase family
MST18_10585	COG1113	amino acid transport
MST18_10615	COG0446	pyridine nucleotide-disulphide oxidoreductase
MST18_10615	COG1902	pentaerythritol trinitrate reductase activity
MST18_10620	COG0277	FAD linked oxidase domain protein
MST18_10630	COG2186	Transcriptional regulator
MST18_10645	COG3706	GGDEF domain
MST18_10650	COG0418	dihydroorotase activity
MST18_10655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MST18_10665	COG4771	TonB-dependent receptor
MST18_10685	COG0833	amino acid
MST18_10700	COG0833	amino acid
MST18_10725	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MST18_10735	COG4172	Belongs to the ABC transporter superfamily
MST18_10740	COG4239	(ABC) transporter, permease
MST18_10745	COG4174	ABC transporter (Permease)
MST18_10750	COG4166	transmembrane transport
MST18_10755	COG1388	LysM domain
MST18_10755	COG0741	lytic transglycosylase activity
MST18_10775	COG0657	acetylesterase activity
MST18_10810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MST18_10815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MST18_10825	COG0006	proline dipeptidase activity
MST18_10885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MST18_10895	COG2234	aminopeptidase activity
MST18_10905	COG3384	dioxygenase
MST18_10915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MST18_10920	COG2878	Part of a membrane complex involved in electron transport
MST18_10925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MST18_10950	COG0768	penicillin binding
MST18_10955	COG0742	ribosomal rna small subunit methyltransferase
MST18_11010	COG1597	lipid kinase activity
MST18_11015	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MST18_11025	COG0477	Major facilitator Superfamily
MST18_11030	COG0477	Major facilitator Superfamily
MST18_11045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MST18_11080	COG1695	Transcriptional regulator
MST18_11095	COG0175	sulfate reduction
MST18_11110	COG2268	Band 7 protein
MST18_11115	COG0726	polysaccharide deacetylase
MST18_11115	COG1649	PFAM Uncharacterised BCR, COG1649
MST18_11125	COG1215	transferase activity, transferring glycosyl groups
MST18_11130	COG1649	PFAM Uncharacterised BCR, COG1649
MST18_11130	COG0726	polysaccharide deacetylase
MST18_11140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MST18_11150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MST18_11165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MST18_11170	COG1053	succinate dehydrogenase
MST18_11175	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MST18_11190	COG2072	flavoprotein involved in K transport
MST18_11205	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MST18_11275	COG2321	neutral zinc metallopeptidase
MST18_11280	COG2354	Protein conserved in bacteria
MST18_11305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MST18_11310	COG1773	rubredoxin
MST18_11315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST18_11325	COG0583	DNA-binding transcription factor activity
MST18_11350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MST18_11355	COG4181	ATPase activity
MST18_11405	COG0306	phosphate transporter
MST18_11420	COG2376	Dihydroxyacetone kinase
MST18_11425	COG2323	membrane
MST18_11430	COG0004	ammonium transporteR
MST18_11445	COG0642	Histidine kinase
MST18_11450	COG0745	RESPONSE REGULATOR receiver
MST18_11455	COG2194	sulfuric ester hydrolase activity
MST18_11475	COG1752	Esterase of the alpha-beta hydrolase superfamily
MST18_11490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MST18_11495	COG0142	geranyltranstransferase activity
MST18_11500	COG3706	GGDEF domain
MST18_11505	COG2828	Protein conserved in bacteria
MST18_11510	COG1113	amino acid transport
MST18_11540	COG0560	Phosphoserine phosphatase
MST18_11550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MST18_11560	COG1530	ribonuclease E activity
MST18_11565	COG0424	maF-like protein
MST18_11570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MST18_11575	COG1792	Involved in formation and maintenance of cell shape
MST18_11580	COG1077	Cell shape determining protein MreB Mrl
MST18_11585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MST18_11595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MST18_11645	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MST18_11680	COG1053	succinate dehydrogenase
MST18_11685	COG0583	DNA-binding transcription factor activity
MST18_11695	COG1294	oxidase, subunit
MST18_11700	COG1271	oxidase subunit
MST18_11740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MST18_11755	COG0642	Histidine kinase
MST18_11765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MST18_11785	COG1250	3-hydroxyacyl-CoA dehydrogenase
MST18_11790	COG1024	Enoyl-CoA hydratase
MST18_11795	COG1960	acyl-CoA dehydrogenase activity
MST18_11805	COG0427	acetyl-CoA hydrolase
MST18_11810	COG0183	Belongs to the thiolase family
MST18_11820	COG0583	DNA-binding transcription factor activity
MST18_11825	COG1960	acyl-CoA dehydrogenase activity
MST18_11830	COG2301	Belongs to the HpcH HpaI aldolase family
MST18_11835	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MST18_11840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MST18_11845	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MST18_11845	COG0644	oxidoreductase
MST18_11865	COG0515	serine threonine protein kinase
MST18_11865	COG2815	serine threonine protein kinase
MST18_11960	COG0582	viral genome integration into host DNA
MST18_11970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MST18_11975	COG2814	Major facilitator Superfamily
MST18_11980	COG1566	PFAM secretion protein HlyD family protein
MST18_11985	COG2050	protein possibly involved in aromatic compounds catabolism
MST18_11995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MST18_12000	COG1090	epimerase
MST18_12010	COG2203	Gaf domain
MST18_12010	COG3706	GGDEF domain
MST18_12010	COG4251	negative regulation of phosphorylation
MST18_12010	COG5001	Diguanylate cyclase
MST18_12025	COG0420	3'-5' exonuclease activity
MST18_12055	COG0735	belongs to the Fur family
MST18_12060	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MST18_12065	COG2914	Belongs to the UPF0125 (RnfH) family
MST18_12080	COG0121	glutamine amidotransferase
MST18_12090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MST18_12100	COG0210	DNA helicase
MST18_12105	COG2885	chlorophyll binding
MST18_12110	COG0204	Acyl-transferase
MST18_12130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MST18_12145	COG0583	DNA-binding transcription factor activity
MST18_12150	COG1674	ftsk spoiiie
MST18_12155	COG0492	ferredoxin-NADP+ reductase activity
MST18_12160	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MST18_12165	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MST18_12170	COG0456	acetyltransferase
MST18_12185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MST18_12210	COG1981	membrane
MST18_12225	COG1652	LysM domain
MST18_12235	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_12250	COG1399	metal-binding, possibly nucleic acid-binding protein
MST18_12255	COG3101	peptidyl-lysine hydroxylation
MST18_12260	COG0009	L-threonylcarbamoyladenylate synthase
MST18_12275	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MST18_12280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MST18_12295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MST18_12355	COG4106	trans-aconitate 2-methyltransferase activity
MST18_12370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MST18_12370	COG2226	methyltransferase
MST18_12370	COG0596	Alpha beta hydrolase
MST18_12375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MST18_12380	COG2193	ferroxidase activity
MST18_12385	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MST18_12395	COG2801	Transposase and inactivated derivatives
MST18_12400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MST18_12420	COG0183	Belongs to the thiolase family
MST18_12435	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST18_12450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MST18_12455	COG2207	Transcriptional regulator
MST18_12465	COG0183	Belongs to the thiolase family
MST18_12470	COG1024	Enoyl-CoA hydratase
MST18_12470	COG1250	3-hydroxyacyl-CoA dehydrogenase
MST18_12490	COG1272	protein, Hemolysin III
MST18_12495	COG0477	Major facilitator Superfamily
MST18_12500	COG1408	metallophosphoesterase
MST18_12505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MST18_12515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MST18_12545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MST18_12550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MST18_12570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MST18_12575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MST18_12585	COG0625	glutathione transferase activity
MST18_12590	COG2969	positive regulation of protein catabolic process
MST18_12660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MST18_12665	COG1764	response to oxidative stress
MST18_12700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MST18_12700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MST18_12715	COG0037	tRNA processing
MST18_12750	COG0072	phenylalanine-tRNA ligase activity
MST18_12805	COG1238	metal cluster binding
MST18_12820	COG0625	glutathione transferase activity
MST18_12830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MST18_12840	COG0069	glutamate synthase activity
MST18_12855	COG0318	PFAM AMP-dependent synthetase and ligase
MST18_12860	COG3028	Belongs to the UPF0307 family
MST18_12865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MST18_12870	COG1660	Displays ATPase and GTPase activities
MST18_12885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MST18_12890	COG0617	tRNA 3'-terminal CCA addition
MST18_12895	COG1555	photosystem II stabilization
MST18_12895	COG1596	polysaccharide export
MST18_12900	COG3956	TIGRFAM MazG family protein
MST18_12930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MST18_12950	COG1426	Protein conserved in bacteria
MST18_12985	COG3851	Histidine kinase
MST18_13025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MST18_13030	COG0440	acetolactate synthase activity
MST18_13035	COG0028	Belongs to the TPP enzyme family
MST18_13055	COG1466	dna polymerase III delta subunit
MST18_13060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST18_13065	COG0577	efflux transmembrane transporter activity
MST18_13065	COG1136	(ABC) transporter
MST18_13070	COG1538	Outer membrane efflux protein
MST18_13100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MST18_13110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MST18_13115	COG1162	GTPase activity
MST18_13130	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MST18_13140	COG0084	hydrolase, TatD family'
MST18_13155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MST18_13165	COG0793	Belongs to the peptidase S41A family
MST18_13180	COG2267	carboxylic ester hydrolase activity
MST18_13190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MST18_13195	COG0280	phosphate acetyltransferase
MST18_13195	COG0857	belongs to the CobB CobQ family
MST18_13205	COG3540	Alkaline phosphatase
MST18_13215	COG0456	acetyltransferase
MST18_13235	COG0740	serine-type endopeptidase activity
MST18_13245	COG4771	TonB-dependent receptor
MST18_13250	COG4774	siderophore transport
MST18_13265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MST18_13275	COG2813	Specifically methylates the guanine in position
MST18_13275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MST18_13345	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MST18_13385	COG0788	formyltetrahydrofolate deformylase activity
MST18_13410	COG4651	solute:proton antiporter activity
MST18_13410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MST18_13440	COG0210	DNA helicase
MST18_13450	COG1929	Belongs to the glycerate kinase type-1 family
MST18_13485	COG2900	Belongs to the SlyX family
MST18_13490	COG0488	(ABC) transporter
MST18_13495	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_13500	COG1560	Kdo2-lipid A biosynthetic process
MST18_13535	COG0252	asparaginase activity
MST18_13565	COG0473	3-isopropylmalate dehydrogenase activity
MST18_13580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MST18_13595	COG0583	DNA-binding transcription factor activity
MST18_13615	COG0494	nUDIX hydrolase
MST18_13630	COG1960	acyl-CoA dehydrogenase activity
MST18_13645	COG0753	catalase activity
MST18_13665	COG0446	pyridine nucleotide-disulphide oxidoreductase
MST18_13670	COG3384	dioxygenase
MST18_13675	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_13690	COG4638	Rieske (2fe-2S)
MST18_13695	COG0583	DNA-binding transcription factor activity
MST18_13710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MST18_13715	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MST18_13720	COG3971	2-oxopent-4-enoate hydratase activity
MST18_13735	COG1530	ribonuclease E activity
MST18_13740	COG0318	PFAM AMP-dependent synthetase and ligase
MST18_13770	COG1983	PspC domain protein
MST18_13775	COG0517	IMP dehydrogenase activity
MST18_13775	COG0617	tRNA 3'-terminal CCA addition
MST18_13775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MST18_13790	COG0752	glycyl-tRNA synthetase alpha subunit
MST18_13795	COG0751	glycine-tRNA ligase activity
MST18_13830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MST18_13860	COG0493	'glutamate synthase
MST18_13870	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MST18_13875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MST18_13890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MST18_13900	COG0644	oxidoreductase
MST18_13900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MST18_13915	COG0425	Belongs to the sulfur carrier protein TusA family
MST18_13920	COG4535	Mg2 and Co2 transporter CorC
MST18_13925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MST18_13930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MST18_13950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MST18_13960	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MST18_13985	COG0789	Transcriptional regulator
MST18_13990	COG2841	Protein conserved in bacteria
MST18_14005	COG0598	Magnesium transport protein CorA
MST18_14020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MST18_14025	COG1074	ATP-dependent DNA helicase activity
MST18_14030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MST18_14060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MST18_14085	COG2183	response to ionizing radiation
MST18_14100	COG0427	acetyl-CoA hydrolase
MST18_14110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MST18_14155	COG0326	Molecular chaperone. Has ATPase activity
MST18_14165	COG3047	cAMP biosynthetic process
MST18_14170	COG2056	Na+-H+ antiporter family
MST18_14195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MST18_14200	COG0085	RNA polymerase activity
MST18_14210	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MST18_14215	COG0081	regulation of translation
MST18_14230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MST18_14270	COG0546	phosphoglycolate phosphatase activity
MST18_14320	COG0181	hydroxymethylbilane synthase activity
MST18_14330	COG3275	phosphorelay sensor kinase activity
MST18_14345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MST18_14355	COG0322	excinuclease ABC activity
MST18_14370	COG3706	GGDEF domain
MST18_14385	COG1250	3-hydroxyacyl-CoA dehydrogenase
MST18_14385	COG1024	Enoyl-CoA hydratase
MST18_14470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MST18_14485	COG3152	Membrane
MST18_14505	COG0697	spore germination
MST18_14515	COG0531	amino acid
MST18_14530	COG1278	Cold shock
MST18_14535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MST18_14555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MST18_14575	COG3158	transport of potassium into the cell
MST18_14600	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MST18_14610	COG1335	isochorismatase
MST18_14615	COG0583	DNA-binding transcription factor activity
MST18_14625	COG0629	single-stranded DNA binding
MST18_14630	COG2814	Major facilitator Superfamily
MST18_14640	COG0351	phosphomethylpyrimidine kinase
MST18_14640	COG0352	thiamine-phosphate diphosphorylase activity
MST18_14640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MST18_14705	COG3162	membrane
MST18_14710	COG2205	protein histidine kinase activity
MST18_14710	COG0784	Response regulator, receiver
MST18_14725	COG0431	NADPH-dependent FMN reductase
MST18_14730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST18_14740	COG0307	riboflavin synthase, alpha
MST18_14750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MST18_14760	COG0668	transmembrane transport
MST18_14765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MST18_14770	COG1519	Transferase
MST18_14775	COG1902	pentaerythritol trinitrate reductase activity
MST18_14800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MST18_14825	COG0426	domain, Protein
MST18_14825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MST18_14830	COG2119	membrane
MST18_14865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MST18_14875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MST18_14885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MST18_14895	COG0189	ligase activity
MST18_14900	COG3706	GGDEF domain
MST18_14925	COG0708	Exodeoxyribonuclease III
MST18_14930	COG1393	Belongs to the ArsC family
MST18_14950	COG3706	GGDEF domain
MST18_15025	COG3150	esterase
MST18_15035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MST18_15040	COG2918	glutathione biosynthetic process
MST18_15055	COG2733	membrane
MST18_15125	COG3830	Belongs to the UPF0237 family
MST18_15125	COG0560	Phosphoserine phosphatase
MST18_15140	COG0385	Bile acid
MST18_15145	COG1335	isochorismatase
MST18_15155	COG2814	Major facilitator Superfamily
MST18_15160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MST18_15170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MST18_15175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MST18_15185	COG1683	Conserved Protein
MST18_15190	COG2983	Belongs to the UPF0260 family
MST18_15195	COG5487	UPF0391 membrane protein
MST18_15205	COG3023	N-Acetylmuramoyl-L-alanine amidase
MST18_15235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MST18_15240	COG0546	phosphoglycolate phosphatase activity
MST18_15245	COG1028	Short-chain dehydrogenase reductase Sdr
MST18_15270	COG0675	Transposase, IS605 OrfB family
MST18_15275	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MST18_15275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MST18_15280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST18_15285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST18_15290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST18_15295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST18_15300	COG1116	anion transmembrane transporter activity
MST18_15305	COG1309	transcriptional regulator
MST18_15325	COG0196	riboflavin kinase activity
MST18_15330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MST18_15335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MST18_15340	COG1047	Peptidyl-prolyl cis-trans
MST18_15365	COG2133	pyrroloquinoline quinone binding
MST18_15370	COG0693	protein deglycase activity
MST18_15385	COG2814	Major facilitator Superfamily
MST18_15430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MST18_15435	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MST18_15440	COG2951	lytic endotransglycosylase activity
MST18_15445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MST18_15465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MST18_15480	COG2388	GCN5-related N-acetyl-transferase
MST18_15485	COG2814	Major facilitator Superfamily
MST18_15490	COG0861	Integral membrane protein TerC family
MST18_15500	COG0402	S-adenosylhomocysteine deaminase activity
MST18_15515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MST18_15520	COG1230	cation diffusion facilitator family transporter
MST18_15545	COG0706	membrane insertase activity
MST18_15550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MST18_15555	COG0594	ribonuclease P activity
MST18_15630	COG1373	ATPase (AAA superfamily
MST18_15660	COG3173	Aminoglycoside phosphotransferase
MST18_15685	COG4974	Belongs to the 'phage' integrase family
MST18_15715	COG1683	Conserved Protein
MST18_15750	COG1230	cation diffusion facilitator family transporter
MST18_15760	COG0789	Transcriptional regulator
MST18_15765	COG0582	viral genome integration into host DNA
MST18_15805	COG2184	nucleotidyltransferase activity
MST18_15890	COG2801	Transposase and inactivated derivatives
MST18_15895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MST18_15905	COG1063	alcohol dehydrogenase
MST18_15960	COG1192	Involved in chromosome partitioning
MST18_15965	COG1475	DNA binding
MST18_15990	COG1660	Displays ATPase and GTPase activities
MST18_16020	COG0745	RESPONSE REGULATOR receiver
MST18_16025	COG5002	protein histidine kinase activity
MST18_16035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MST18_16055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MST18_16160	COG0583	DNA-binding transcription factor activity
MST18_16230	COG4221	oxidoreductase activity
MST18_16410	COG0488	(ABC) transporter
MST18_16415	COG3173	Aminoglycoside phosphotransferase
MST18_16445	COG0488	(ABC) transporter
MST18_16450	COG3173	Aminoglycoside phosphotransferase
MST18_16475	COG0488	(ABC) transporter
MST18_16485	COG3077	Addiction module antitoxin, RelB DinJ family
MST18_16510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MST18_16565	COG0583	DNA-binding transcription factor activity