locus-tag	class	description
MST16_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MST16_00010	COG0592	DNA-directed DNA polymerase activity
MST16_00020	COG0187	DNA topoisomerase II activity
MST16_00030	COG0488	(ABC) transporter
MST16_00085	COG0657	acetylesterase activity
MST16_00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MST16_00130	COG2814	Major facilitator Superfamily
MST16_00160	COG0693	protein deglycase activity
MST16_00165	COG2133	pyrroloquinoline quinone binding
MST16_00190	COG0675	Transposase, IS605 OrfB family
MST16_00200	COG1047	Peptidyl-prolyl cis-trans
MST16_00210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MST16_00215	COG0196	riboflavin kinase activity
MST16_00235	COG1309	transcriptional regulator
MST16_00240	COG1116	anion transmembrane transporter activity
MST16_00245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST16_00250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST16_00255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST16_00260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST16_00265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MST16_00265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MST16_00270	COG0675	Transposase, IS605 OrfB family
MST16_00295	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_00300	COG0546	phosphoglycolate phosphatase activity
MST16_00305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MST16_00320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MST16_00335	COG3023	N-Acetylmuramoyl-L-alanine amidase
MST16_00345	COG5487	UPF0391 membrane protein
MST16_00350	COG2983	Belongs to the UPF0260 family
MST16_00355	COG1683	Conserved Protein
MST16_00365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MST16_00370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MST16_00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MST16_00385	COG2814	Major facilitator Superfamily
MST16_00395	COG1335	isochorismatase
MST16_00400	COG0385	Bile acid
MST16_00415	COG0560	Phosphoserine phosphatase
MST16_00415	COG3830	Belongs to the UPF0237 family
MST16_00500	COG2733	membrane
MST16_00515	COG2918	glutathione biosynthetic process
MST16_00520	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MST16_00530	COG3150	esterase
MST16_00605	COG3706	GGDEF domain
MST16_00625	COG1393	Belongs to the ArsC family
MST16_00630	COG0708	Exodeoxyribonuclease III
MST16_00670	COG2801	Transposase and inactivated derivatives
MST16_00680	COG3706	GGDEF domain
MST16_00685	COG0189	ligase activity
MST16_00695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MST16_00705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MST16_00715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MST16_00750	COG2119	membrane
MST16_00755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MST16_00755	COG0426	domain, Protein
MST16_00780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MST16_00805	COG1902	pentaerythritol trinitrate reductase activity
MST16_00810	COG1519	Transferase
MST16_00815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MST16_00820	COG0668	transmembrane transport
MST16_00830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MST16_00840	COG0307	riboflavin synthase, alpha
MST16_00870	COG0431	NADPH-dependent FMN reductase
MST16_00890	COG2205	protein histidine kinase activity
MST16_00890	COG0784	Response regulator, receiver
MST16_00895	COG3162	membrane
MST16_00900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MST16_00960	COG0352	thiamine-phosphate diphosphorylase activity
MST16_00960	COG0351	phosphomethylpyrimidine kinase
MST16_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MST16_00970	COG2814	Major facilitator Superfamily
MST16_00975	COG0629	single-stranded DNA binding
MST16_01005	COG1335	isochorismatase
MST16_01015	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MST16_01105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MST16_01125	COG0582	viral genome integration into host DNA
MST16_01135	COG3158	transport of potassium into the cell
MST16_01155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MST16_01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MST16_01180	COG1278	Cold shock
MST16_01190	COG0697	spore germination
MST16_01210	COG3152	Membrane
MST16_01220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MST16_01255	COG2226	methyltransferase
MST16_01280	COG3706	GGDEF domain
MST16_01315	COG3706	GGDEF domain
MST16_01330	COG0322	excinuclease ABC activity
MST16_01340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MST16_01360	COG3275	phosphorelay sensor kinase activity
MST16_01370	COG0181	hydroxymethylbilane synthase activity
MST16_01420	COG0546	phosphoglycolate phosphatase activity
MST16_01460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MST16_01475	COG0081	regulation of translation
MST16_01480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MST16_01495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MST16_01520	COG2056	Na+-H+ antiporter family
MST16_01525	COG3047	cAMP biosynthetic process
MST16_01535	COG0326	Molecular chaperone. Has ATPase activity
MST16_01575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MST16_01585	COG0427	acetyl-CoA hydrolase
MST16_01600	COG2183	response to ionizing radiation
MST16_01630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MST16_01660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MST16_01665	COG1074	ATP-dependent DNA helicase activity
MST16_01670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MST16_01685	COG0598	Magnesium transport protein CorA
MST16_01690	COG2841	Protein conserved in bacteria
MST16_01695	COG0789	Transcriptional regulator
MST16_01720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MST16_01730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MST16_01750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MST16_01755	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MST16_01760	COG4535	Mg2 and Co2 transporter CorC
MST16_01765	COG0425	Belongs to the sulfur carrier protein TusA family
MST16_01785	COG0644	oxidoreductase
MST16_01785	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MST16_01795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MST16_01810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MST16_01815	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MST16_01825	COG0493	'glutamate synthase
MST16_01855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MST16_01895	COG0751	glycine-tRNA ligase activity
MST16_01900	COG0752	glycyl-tRNA synthetase alpha subunit
MST16_01915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MST16_01915	COG0517	IMP dehydrogenase activity
MST16_01915	COG0617	tRNA 3'-terminal CCA addition
MST16_01920	COG1983	PspC domain protein
MST16_01950	COG0318	PFAM AMP-dependent synthetase and ligase
MST16_01955	COG1530	ribonuclease E activity
MST16_01965	COG0546	phosphoglycolate phosphatase activity
MST16_01970	COG3971	2-oxopent-4-enoate hydratase activity
MST16_01975	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MST16_01980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MST16_01995	COG0583	DNA-binding transcription factor activity
MST16_02000	COG4638	Rieske (2fe-2S)
MST16_02015	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_02020	COG3384	dioxygenase
MST16_02025	COG0446	pyridine nucleotide-disulphide oxidoreductase
MST16_02050	COG0753	catalase activity
MST16_02065	COG1960	acyl-CoA dehydrogenase activity
MST16_02090	COG0494	nUDIX hydrolase
MST16_02110	COG0583	DNA-binding transcription factor activity
MST16_02125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MST16_02140	COG0473	3-isopropylmalate dehydrogenase activity
MST16_02170	COG0252	asparaginase activity
MST16_02210	COG1560	Kdo2-lipid A biosynthetic process
MST16_02215	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_02220	COG0488	(ABC) transporter
MST16_02225	COG2900	Belongs to the SlyX family
MST16_02270	COG1929	Belongs to the glycerate kinase type-1 family
MST16_02310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MST16_02310	COG4651	solute:proton antiporter activity
MST16_02335	COG0788	formyltetrahydrofolate deformylase activity
MST16_02375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MST16_02445	COG2813	Specifically methylates the guanine in position
MST16_02445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MST16_02455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MST16_02470	COG4774	siderophore transport
MST16_02475	COG4771	TonB-dependent receptor
MST16_02485	COG0740	serine-type endopeptidase activity
MST16_02520	COG3540	Alkaline phosphatase
MST16_02530	COG0280	phosphate acetyltransferase
MST16_02530	COG0857	belongs to the CobB CobQ family
MST16_02535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MST16_02545	COG2267	carboxylic ester hydrolase activity
MST16_02560	COG0793	Belongs to the peptidase S41A family
MST16_02570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MST16_02585	COG0084	hydrolase, TatD family'
MST16_02595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MST16_02610	COG1162	GTPase activity
MST16_02615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MST16_02620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MST16_02705	COG1538	Outer membrane efflux protein
MST16_02710	COG0577	efflux transmembrane transporter activity
MST16_02710	COG1136	(ABC) transporter
MST16_02715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST16_02720	COG2703	oxygen carrier activity
MST16_02725	COG1466	dna polymerase III delta subunit
MST16_02745	COG0028	Belongs to the TPP enzyme family
MST16_02750	COG0440	acetolactate synthase activity
MST16_02755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MST16_02840	COG1426	Protein conserved in bacteria
MST16_02860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MST16_02890	COG3956	TIGRFAM MazG family protein
MST16_02895	COG1555	photosystem II stabilization
MST16_02895	COG1596	polysaccharide export
MST16_02900	COG0617	tRNA 3'-terminal CCA addition
MST16_02905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MST16_02920	COG1660	Displays ATPase and GTPase activities
MST16_02925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MST16_02930	COG3028	Belongs to the UPF0307 family
MST16_02935	COG0318	PFAM AMP-dependent synthetase and ligase
MST16_02950	COG0069	glutamate synthase activity
MST16_02960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MST16_02970	COG0625	glutathione transferase activity
MST16_02985	COG1238	metal cluster binding
MST16_03035	COG0072	phenylalanine-tRNA ligase activity
MST16_03060	COG0248	Ppx GppA phosphatase
MST16_03070	COG0037	tRNA processing
MST16_03085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MST16_03085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MST16_03120	COG1764	response to oxidative stress
MST16_03125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MST16_03190	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MST16_03195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MST16_03255	COG1214	PFAM Peptidase M22, glycoprotease
MST16_03260	COG1968	undecaprenyl-diphosphatase activity
MST16_03280	COG4269	membrane
MST16_03295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MST16_03305	COG2132	Multicopper oxidase
MST16_03315	COG2076	Multidrug Resistance protein
MST16_03340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MST16_03345	COG1278	Cold shock
MST16_03355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MST16_03380	COG0730	response to heat
MST16_03390	COG1196	nuclear chromosome segregation
MST16_03400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MST16_03405	COG0833	amino acid
MST16_03415	COG2233	PERMEase
MST16_03420	COG1217	gtp-binding protein TYPA
MST16_03435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MST16_03445	COG3659	wide pore channel activity
MST16_03450	COG4772	TonB-dependent receptor
MST16_03455	COG1902	pentaerythritol trinitrate reductase activity
MST16_03485	COG0354	folic acid binding
MST16_03490	COG2132	Multicopper oxidase
MST16_03495	COG2132	Multicopper oxidase
MST16_03510	COG4456	Virulence-associated protein
MST16_03515	COG1487	ribonuclease activity
MST16_03555	COG0564	pseudouridine synthase activity
MST16_03575	COG3189	MarR family transcriptional regulator
MST16_03580	COG2824	Alkylphosphonate utilization operon protein PhnA
MST16_03590	COG3422	double-strand break repair
MST16_03605	COG0628	permease
MST16_03610	COG5342	invasion associated locus B
MST16_03615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MST16_03615	COG0352	thiamine-phosphate diphosphorylase activity
MST16_03615	COG0351	phosphomethylpyrimidine kinase
MST16_03635	COG2314	TM2 domain
MST16_03650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MST16_03660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MST16_03660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MST16_03665	COG0745	RESPONSE REGULATOR receiver
MST16_03670	COG2205	protein histidine kinase activity
MST16_03700	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MST16_03715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MST16_03725	COG0713	ATP synthesis coupled electron transport
MST16_03730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MST16_03735	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MST16_03745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MST16_03755	COG1278	Cold shock
MST16_03760	COG0583	DNA-binding transcription factor activity
MST16_03770	COG1126	abc transporter atp-binding protein
MST16_03775	COG0765	amino acid transport
MST16_03780	COG0765	amino acid transport
MST16_03800	COG0668	transmembrane transport
MST16_03815	COG2081	HI0933 family
MST16_03870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MST16_03870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MST16_03890	COG0489	protein tyrosine kinase activity
MST16_03905	COG2358	TRAP transporter, solute receptor (TAXI family
MST16_03940	COG0442	prolyl-tRNA aminoacylation
MST16_03975	COG0840	transmembrane signaling receptor activity
MST16_03980	COG2198	Histidine kinase
MST16_03980	COG0643	Histidine kinase
MST16_03995	COG5510	response to toxic substance
MST16_04005	COG2832	Protein of unknown function (DUF454)
MST16_04065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MST16_04075	COG1289	transmembrane transporter activity
MST16_04080	COG2814	Major facilitator Superfamily
MST16_04090	COG0786	glutamate:sodium symporter activity
MST16_04095	COG1115	amino acid carrier protein
MST16_04100	COG1752	Esterase of the alpha-beta hydrolase superfamily
MST16_04110	COG1607	acyl-coa hydrolase
MST16_04120	COG2814	Major facilitator Superfamily
MST16_04125	COG0583	DNA-binding transcription factor activity
MST16_04160	COG0523	cobalamin synthesis protein
MST16_04165	COG4681	YaeQ
MST16_04170	COG1285	pathogenesis
MST16_04180	COG2203	Gaf domain
MST16_04180	COG2199	diguanylate cyclase activity
MST16_04205	COG1024	Enoyl-CoA hydratase
MST16_04230	COG0477	Major facilitator Superfamily
MST16_04235	COG0242	peptide deformylase activity
MST16_04250	COG2066	Belongs to the glutaminase family
MST16_04275	COG0525	valine-tRNA ligase activity
MST16_04285	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_04300	COG0393	Putative heavy-metal-binding
MST16_04305	COG1538	Outer membrane efflux protein
MST16_04315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST16_04320	COG0671	phosphoesterase, PA-phosphatase related
MST16_04335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MST16_04340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MST16_04355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MST16_04365	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MST16_04370	COG1648	precorrin-2 dehydrogenase activity
MST16_04370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MST16_04375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MST16_04415	COG0531	amino acid
MST16_04430	COG0321	lipoyl(octanoyl) transferase activity
MST16_04440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MST16_04465	COG0586	Pfam SNARE associated Golgi protein
MST16_04490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MST16_04515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MST16_04520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MST16_04550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MST16_04565	COG0358	DNA primase activity
MST16_04575	COG0564	pseudouridine synthase activity
MST16_04630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MST16_04695	COG0110	maltose O-acetyltransferase activity
MST16_04735	COG0505	Belongs to the CarA family
MST16_04760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MST16_04765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MST16_04795	COG2851	Citrate transporter
MST16_04805	COG1253	flavin adenine dinucleotide binding
MST16_04835	COG0584	glycerophosphoryl diester phosphodiesterase
MST16_04845	COG2239	Acts as a magnesium transporter
MST16_04860	COG0741	lytic transglycosylase activity
MST16_04860	COG0739	heme binding
MST16_04860	COG1196	nuclear chromosome segregation
MST16_04865	COG0037	tRNA processing
MST16_04875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MST16_04880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MST16_04895	COG0235	Class ii aldolase
MST16_04905	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MST16_04920	COG0280	phosphate acetyltransferase
MST16_04920	COG0281	malic enzyme
MST16_04930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MST16_04935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MST16_04940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MST16_04960	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MST16_04995	COG1115	amino acid carrier protein
MST16_05000	COG1113	amino acid transport
MST16_05010	COG0019	diaminopimelate decarboxylase activity
MST16_05025	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MST16_05035	COG1522	sequence-specific DNA binding
MST16_05040	COG1280	lysine exporter protein (LysE YggA)
MST16_05080	COG1301	dicarboxylic acid transport
MST16_05100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST16_05120	COG1671	Belongs to the UPF0178 family
MST16_05125	COG0697	spore germination
MST16_05140	COG1136	(ABC) transporter
MST16_05145	COG2333	competence protein COMEC
MST16_05145	COG0658	competence protein
MST16_05170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MST16_05175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MST16_05180	COG0628	permease
MST16_05215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MST16_05235	COG0823	Involved in the tonB-independent uptake of proteins
MST16_05260	COG0824	Thioesterase
MST16_05270	COG2255	four-way junction helicase activity
MST16_05285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MST16_05285	COG0047	phosphoribosylformylglycinamidine synthase activity
MST16_05300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MST16_05300	COG3323	Protein of unknown function (DUF1653)
MST16_05305	COG0778	Nitroreductase
MST16_05310	COG1024	Enoyl-CoA hydratase
MST16_05315	COG1056	cytidyltransferase-related domain
MST16_05315	COG1051	belongs to the nudix hydrolase family
MST16_05320	COG2353	YceI-like domain
MST16_05325	COG0583	DNA-binding transcription factor activity
MST16_05335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MST16_05345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MST16_05350	COG0602	queuosine metabolic process
MST16_05370	COG0583	DNA-binding transcription factor activity
MST16_05375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MST16_05380	COG4208	sulfate ABC transporter
MST16_05395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MST16_05400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MST16_05405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MST16_05410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MST16_05415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MST16_05430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MST16_05445	COG0681	Belongs to the peptidase S26 family
MST16_05455	COG0571	ribonuclease III activity
MST16_05460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MST16_05470	COG1381	Involved in DNA repair and RecF pathway recombination
MST16_05475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MST16_05510	COG0436	Aminotransferase
MST16_05520	COG0052	Belongs to the universal ribosomal protein uS2 family
MST16_05545	COG2951	lytic endotransglycosylase activity
MST16_05560	COG0842	Transport permease protein
MST16_05565	COG1131	(ABC) transporter
MST16_05575	COG0582	viral genome integration into host DNA
MST16_05610	COG3177	Filamentation induced by cAMP protein fic
MST16_05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST16_05625	COG1136	(ABC) transporter
MST16_05665	COG3046	protein related to deoxyribodipyrimidine photolyase
MST16_05710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MST16_05725	COG0642	Histidine kinase
MST16_05760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MST16_05810	COG1741	Belongs to the pirin family
MST16_05825	COG3739	integral membrane protein
MST16_05840	COG3706	GGDEF domain
MST16_05850	COG0302	gtp cyclohydrolase
MST16_05880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MST16_05885	COG0512	Glutamine amidotransferase of anthranilate synthase
MST16_05890	COG0174	glutamine synthetase
MST16_05905	COG3161	chorismate lyase activity
MST16_05910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MST16_05950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MST16_05955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MST16_05960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MST16_05980	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MST16_05990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MST16_06015	COG0583	DNA-binding transcription factor activity
MST16_06020	COG2175	clavaminate synthase activity
MST16_06040	COG2199	diguanylate cyclase activity
MST16_06050	COG0556	nucleotide-excision repair
MST16_06075	COG1733	regulation of RNA biosynthetic process
MST16_06095	COG0431	NADPH-dependent FMN reductase
MST16_06100	COG0798	PFAM Bile acid sodium symporter
MST16_06110	COG0640	Transcriptional regulator
MST16_06120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MST16_06125	COG0076	glutamate decarboxylase activity
MST16_06135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MST16_06140	COG0573	inorganic phosphate transmembrane transporter activity
MST16_06150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MST16_06155	COG0616	signal peptide processing
MST16_06170	COG3676	manually curated
MST16_06185	COG0482	sulfurtransferase activity
MST16_06225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MST16_06230	COG1686	Belongs to the peptidase S11 family
MST16_06255	COG0583	DNA-binding transcription factor activity
MST16_06260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MST16_06265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MST16_06270	COG1067	ATP-dependent peptidase activity
MST16_06320	COG1966	Carbon starvation protein
MST16_06325	COG2879	small protein
MST16_06330	COG0714	Associated with various cellular activities
MST16_06350	COG3293	Transposase
MST16_06355	COG1765	OsmC-like protein
MST16_06365	COG0667	Aldo Keto reductase
MST16_06370	COG0542	response to heat
MST16_06410	COG0540	Belongs to the ATCase OTCase family
MST16_06430	COG0589	response to stress
MST16_06435	COG0589	response to stress
MST16_06445	COG2076	Multidrug Resistance protein
MST16_06450	COG1309	transcriptional regulator
MST16_06455	COG3135	benzoate transporter
MST16_06465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MST16_06470	COG0583	DNA-binding transcription factor activity
MST16_06485	COG0183	Belongs to the thiolase family
MST16_06500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MST16_06515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MST16_06520	COG0824	Thioesterase
MST16_06525	COG1454	alcohol dehydrogenase
MST16_06530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MST16_06550	COG0069	glutamate synthase activity
MST16_06560	COG2308	Evidence 4 Homologs of previously reported genes of
MST16_06570	COG1305	Transglutaminase-like
MST16_06580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MST16_06585	COG0305	Participates in initiation and elongation during chromosome replication
MST16_06600	COG0360	Binds together with S18 to 16S ribosomal RNA
MST16_06610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MST16_06615	COG1845	cytochrome c oxidase, subunit III
MST16_06620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MST16_06625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MST16_06650	COG4682	membrane
MST16_06655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST16_06675	COG2890	protein-(glutamine-N5) methyltransferase activity
MST16_06685	COG2207	Transcriptional regulator
MST16_06695	COG1960	acyl-CoA dehydrogenase activity
MST16_06700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MST16_06710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MST16_06720	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MST16_06730	COG0586	Pfam SNARE associated Golgi protein
MST16_06745	COG0477	Major facilitator Superfamily
MST16_06750	COG0729	surface antigen
MST16_06775	COG1570	exodeoxyribonuclease VII activity
MST16_06780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MST16_06820	COG0786	glutamate:sodium symporter activity
MST16_06860	COG1114	Component of the transport system for branched-chain amino acids
MST16_06865	COG0024	Methionine aminopeptidase
MST16_06870	COG0583	DNA-binding transcription factor activity
MST16_06875	COG0583	DNA-binding transcription factor activity
MST16_06880	COG2267	carboxylic ester hydrolase activity
MST16_06890	COG0446	pyridine nucleotide-disulphide oxidoreductase
MST16_06890	COG1902	pentaerythritol trinitrate reductase activity
MST16_06905	COG2814	Major facilitator Superfamily
MST16_06915	COG0583	DNA-binding transcription factor activity
MST16_06935	COG0148	phosphopyruvate hydratase activity
MST16_06950	COG0772	Belongs to the SEDS family
MST16_06970	COG4890	Cyd operon protein YbgT
MST16_06975	COG1294	oxidase, subunit
MST16_07025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MST16_07045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MST16_07060	COG0133	tryptophan synthase activity
MST16_07070	COG0516	GMP reductase activity
MST16_07070	COG0517	IMP dehydrogenase activity
MST16_07105	COG0552	protein localization to endoplasmic reticulum
MST16_07210	COG1960	acyl-CoA dehydrogenase activity
MST16_07280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MST16_07285	COG0730	response to heat
MST16_07290	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MST16_07295	COG2207	Transcriptional regulator
MST16_07300	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MST16_07305	COG4589	Belongs to the CDS family
MST16_07320	COG0671	phosphoesterase, PA-phosphatase related
MST16_07320	COG2453	phosphatase
MST16_07325	COG2267	carboxylic ester hydrolase activity
MST16_07330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MST16_07405	COG2223	nitrite transmembrane transporter activity
MST16_07420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MST16_07435	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MST16_07460	COG0583	DNA-binding transcription factor activity
MST16_07485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MST16_07490	COG0671	phosphoesterase, PA-phosphatase related
MST16_07495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MST16_07515	COG1960	acyl-CoA dehydrogenase activity
MST16_07520	COG2207	Transcriptional regulator
MST16_07525	COG2814	Major facilitator Superfamily
MST16_07535	COG3152	Membrane
MST16_07550	COG1960	acyl-CoA dehydrogenase activity
MST16_07600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MST16_07610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MST16_07610	COG1017	nitric oxide dioxygenase activity
MST16_07620	COG0488	(ABC) transporter
MST16_07625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MST16_07635	COG0509	glycine decarboxylation via glycine cleavage system
MST16_07650	COG1132	(ABC) transporter
MST16_07655	COG3706	GGDEF domain
MST16_07660	COG0668	transmembrane transport
MST16_07665	COG3122	Protein conserved in bacteria
MST16_07690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MST16_07700	COG0789	Transcriptional regulator
MST16_07715	COG1960	acyl-CoA dehydrogenase activity
MST16_07720	COG0183	Belongs to the thiolase family
MST16_07725	COG0427	acetyl-CoA hydrolase
MST16_07735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MST16_07765	COG0439	Biotin carboxylase
MST16_07800	COG0864	Transcriptional regulator
MST16_07810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MST16_07815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MST16_07820	COG1959	2 iron, 2 sulfur cluster binding
MST16_07835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MST16_07840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MST16_07845	COG0730	response to heat
MST16_07885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MST16_07895	COG1960	acyl-CoA dehydrogenase activity
MST16_07900	COG2814	Major facilitator Superfamily
MST16_07910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MST16_07915	COG0183	Belongs to the thiolase family
MST16_07920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MST16_07925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MST16_07930	COG4829	muconolactone delta-isomerase
MST16_07935	COG4948	Mandelate Racemase Muconate Lactonizing
MST16_07940	COG0583	DNA-binding transcription factor activity
MST16_07945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST16_07945	COG1116	anion transmembrane transporter activity
MST16_07950	COG0745	RESPONSE REGULATOR receiver
MST16_07955	COG2223	nitrite transmembrane transporter activity
MST16_07960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST16_07965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST16_07970	COG0243	molybdopterin cofactor binding
MST16_07980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MST16_07990	COG0314	molybdopterin synthase activity
MST16_07995	COG0315	cyclic pyranopterin monophosphate synthase activity
MST16_07995	COG0521	Mo-molybdopterin cofactor biosynthetic process
MST16_08000	COG0303	'Molybdopterin
MST16_08005	COG0725	ABC transporter, periplasmic molybdate-binding protein
MST16_08010	COG4149	molybdate abc transporter
MST16_08015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MST16_08050	COG4628	conserved protein (DUF2132)
MST16_08055	COG1464	Belongs to the NlpA lipoprotein family
MST16_08065	COG2011	ABC-type metal ion transport system permease component
MST16_08070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MST16_08075	COG0583	DNA-binding transcription factor activity
MST16_08080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST16_08085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MST16_08105	COG0477	Major facilitator Superfamily
MST16_08115	COG1024	Enoyl-CoA hydratase
MST16_08120	COG1960	acyl-CoA dehydrogenase activity
MST16_08125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MST16_08140	COG0583	DNA-binding transcription factor activity
MST16_08160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MST16_08180	COG2814	Major facilitator Superfamily
MST16_08185	COG0583	DNA-binding transcription factor activity
MST16_08195	COG4638	Rieske (2fe-2S)
MST16_08200	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MST16_08205	COG0633	Ferredoxin
MST16_08205	COG0543	2 iron, 2 sulfur cluster binding
MST16_08210	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_08215	COG3135	benzoate transporter
MST16_08275	COG0318	PFAM AMP-dependent synthetase and ligase
MST16_08365	COG0596	Alpha beta hydrolase
MST16_08430	COG0439	Biotin carboxylase
MST16_08440	COG3706	GGDEF domain
MST16_08445	COG2814	Major facilitator Superfamily
MST16_08450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MST16_08485	COG0372	Belongs to the citrate synthase family
MST16_08515	COG0542	response to heat
MST16_08520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MST16_08530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MST16_08560	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MST16_08565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MST16_08575	COG0569	domain protein
MST16_08580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MST16_08605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MST16_08615	COG1585	Membrane protein implicated in regulation of membrane protease activity
MST16_08645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MST16_08675	COG0822	iron-sulfur transferase activity
MST16_08680	COG0316	Belongs to the HesB IscA family
MST16_08710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MST16_08720	COG1027	Aspartate ammonia-lyase
MST16_08725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MST16_08735	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MST16_08735	COG0506	proline dehydrogenase activity
MST16_08735	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MST16_08755	COG3698	Phosphodiester glycosidase
MST16_08770	COG0667	Aldo Keto reductase
MST16_08775	COG0583	DNA-binding transcription factor activity
MST16_08780	COG3781	membrane
MST16_08825	COG0697	spore germination
MST16_08840	COG0126	phosphoglycerate kinase activity
MST16_08850	COG0424	maF-like protein
MST16_08860	COG2850	peptidyl-arginine hydroxylation
MST16_08870	COG4585	Histidine kinase
MST16_08875	COG2197	response regulator
MST16_08885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MST16_09085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MST16_09125	COG0592	DNA-directed DNA polymerase activity
MST16_09160	COG4974	Belongs to the 'phage' integrase family
MST16_09185	COG1011	Hydrolase
MST16_09190	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MST16_09200	COG2137	regulation of response to DNA damage stimulus
MST16_09215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MST16_09225	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MST16_09250	COG0575	Belongs to the CDS family
MST16_09255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MST16_09270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MST16_09275	COG3852	Histidine kinase
MST16_09290	COG2814	Major facilitator Superfamily
MST16_09325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MST16_09330	COG0138	bifunctional purine biosynthesis protein purh
MST16_09355	COG1464	Belongs to the NlpA lipoprotein family
MST16_09360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MST16_09365	COG2011	ABC-type metal ion transport system permease component
MST16_09420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MST16_09430	COG4122	O-methyltransferase activity
MST16_09465	COG1137	ATPase activity
MST16_09470	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MST16_09480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MST16_09485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MST16_09485	COG0517	IMP dehydrogenase activity
MST16_09510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MST16_09510	COG0519	Catalyzes the synthesis of GMP from XMP
MST16_09515	COG1280	lysine exporter protein (LysE YggA)
MST16_09540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MST16_09555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MST16_09575	COG2391	methyltransferase activity
MST16_09740	COG0352	thiamine-phosphate diphosphorylase activity
MST16_09760	COG1309	transcriptional regulator
MST16_09800	COG0612	Peptidase, M16
MST16_09810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MST16_09815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MST16_09880	COG1610	YqeY-like protein
MST16_09925	COG0167	dihydroorotate dehydrogenase activity
MST16_09950	COG0778	Nitroreductase
MST16_09960	COG0513	Belongs to the DEAD box helicase family
MST16_09965	COG1278	Cold shock
MST16_09980	COG2363	Small membrane protein
MST16_10000	COG0625	glutathione transferase activity
MST16_10005	COG0659	secondary active sulfate transmembrane transporter activity
MST16_10010	COG4585	Histidine kinase
MST16_10015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MST16_10040	COG0308	aminopeptidase N
MST16_10065	COG3293	Transposase
MST16_10080	COG1253	flavin adenine dinucleotide binding
MST16_10115	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MST16_10120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MST16_10135	COG2431	L-lysine efflux transmembrane transporter activity
MST16_10140	COG0284	orotidine-5'-phosphate decarboxylase activity
MST16_10150	COG0776	regulation of translation
MST16_10180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MST16_10215	COG0084	hydrolase, TatD family'
MST16_10235	COG1663	tetraacyldisaccharide 4'-kinase activity
MST16_10240	COG1132	(ABC) transporter
MST16_10250	COG0811	peptide transport
MST16_10255	COG1475	DNA binding
MST16_10260	COG1192	Involved in chromosome partitioning
MST16_10270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MST16_10275	COG3178	'Phosphotransferase
MST16_10285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MST16_10290	COG1923	regulation of RNA biosynthetic process
MST16_10300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MST16_10305	COG0802	atpase or kinase
MST16_10330	COG2707	UPF0756 membrane protein
MST16_10350	COG0583	DNA-binding transcription factor activity
MST16_10355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MST16_10360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MST16_10380	COG1643	Atp-dependent helicase
MST16_10410	COG3634	alkyl hydroperoxide reductase activity
MST16_10425	COG1280	lysine exporter protein (LysE YggA)
MST16_10455	COG1254	Belongs to the acylphosphatase family
MST16_10460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MST16_10460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MST16_10480	COG1944	ATP diphosphatase activity
MST16_10520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MST16_10525	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_10565	COG2986	histidine ammonia-lyase
MST16_10580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MST16_10590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MST16_10595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MST16_10825	COG0732	type I restriction modification DNA specificity domain
MST16_10830	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MST16_10835	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MST16_10910	COG0582	viral genome integration into host DNA
MST16_10945	COG0582	viral genome integration into host DNA
MST16_10995	COG0012	GTP binding
MST16_11010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MST16_11025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MST16_11060	COG0386	Belongs to the glutathione peroxidase family
MST16_11065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MST16_11070	COG0436	Aminotransferase
MST16_11100	COG1187	pseudouridine synthase activity
MST16_11135	COG1686	Belongs to the peptidase S11 family
MST16_11140	COG1252	NADH dehydrogenase
MST16_11180	COG0501	Belongs to the peptidase M48B family
MST16_11185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MST16_11200	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MST16_11215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MST16_11225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MST16_11230	COG0527	aspartate kinase activity
MST16_11240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MST16_11250	COG3038	cytochrome b561
MST16_11260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MST16_11265	COG2252	PERMEase
MST16_11290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MST16_11305	COG0693	protein deglycase activity
MST16_11310	COG1960	acyl-CoA dehydrogenase activity
MST16_11315	COG1301	dicarboxylic acid transport
MST16_11320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MST16_11325	COG3139	Protein of unknown function (DUF1315)
MST16_11330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MST16_11335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MST16_11345	COG0494	nUDIX hydrolase
MST16_11355	COG0642	Histidine kinase
MST16_11370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MST16_11380	COG1720	tRNA m6t6A37 methyltransferase activity
MST16_11440	COG0789	Transcriptional regulator
MST16_11445	COG0826	peptidase U32
MST16_11450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MST16_11455	COG3634	alkyl hydroperoxide reductase activity
MST16_11485	COG2862	Uncharacterized protein family, UPF0114
MST16_11505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MST16_11555	COG0446	pyridine nucleotide-disulphide oxidoreductase
MST16_11555	COG1902	pentaerythritol trinitrate reductase activity
MST16_11560	COG0277	FAD linked oxidase domain protein
MST16_11570	COG2186	Transcriptional regulator
MST16_11585	COG3706	GGDEF domain
MST16_11590	COG0418	dihydroorotase activity
MST16_11595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MST16_11605	COG4771	TonB-dependent receptor
MST16_11640	COG0833	amino acid
MST16_11655	COG0833	amino acid
MST16_11680	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MST16_11690	COG4172	Belongs to the ABC transporter superfamily
MST16_11695	COG4239	(ABC) transporter, permease
MST16_11700	COG4174	ABC transporter (Permease)
MST16_11710	COG0741	lytic transglycosylase activity
MST16_11710	COG1388	LysM domain
MST16_11730	COG0657	acetylesterase activity
MST16_11775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MST16_11780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MST16_11795	COG0006	proline dipeptidase activity
MST16_11860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MST16_11870	COG2234	aminopeptidase activity
MST16_11880	COG3384	dioxygenase
MST16_11890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MST16_11895	COG2878	Part of a membrane complex involved in electron transport
MST16_11900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MST16_11930	COG0768	penicillin binding
MST16_11935	COG0742	ribosomal rna small subunit methyltransferase
MST16_11980	COG1597	lipid kinase activity
MST16_11985	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MST16_12015	COG0477	Major facilitator Superfamily
MST16_12030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MST16_12065	COG1695	Transcriptional regulator
MST16_12085	COG0175	sulfate reduction
MST16_12100	COG2268	Band 7 protein
MST16_12105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MST16_12115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MST16_12130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MST16_12135	COG1053	succinate dehydrogenase
MST16_12140	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MST16_12155	COG2072	flavoprotein involved in K transport
MST16_12170	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MST16_12185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MST16_12185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MST16_12225	COG2321	neutral zinc metallopeptidase
MST16_12230	COG2354	Protein conserved in bacteria
MST16_12250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MST16_12255	COG1773	rubredoxin
MST16_12260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST16_12270	COG0583	DNA-binding transcription factor activity
MST16_12305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MST16_12310	COG4181	ATPase activity
MST16_12360	COG0306	phosphate transporter
MST16_12390	COG2376	Dihydroxyacetone kinase
MST16_12395	COG2323	membrane
MST16_12400	COG0004	ammonium transporteR
MST16_12415	COG0642	Histidine kinase
MST16_12420	COG0745	RESPONSE REGULATOR receiver
MST16_12425	COG2194	sulfuric ester hydrolase activity
MST16_12445	COG1752	Esterase of the alpha-beta hydrolase superfamily
MST16_12460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MST16_12465	COG0142	geranyltranstransferase activity
MST16_12470	COG3706	GGDEF domain
MST16_12475	COG2828	Protein conserved in bacteria
MST16_12480	COG1113	amino acid transport
MST16_12510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MST16_12520	COG1530	ribonuclease E activity
MST16_12525	COG0424	maF-like protein
MST16_12530	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MST16_12535	COG1792	Involved in formation and maintenance of cell shape
MST16_12540	COG1077	Cell shape determining protein MreB Mrl
MST16_12545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MST16_12555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MST16_12595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MST16_12605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MST16_12625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MST16_12630	COG2814	Major facilitator Superfamily
MST16_12635	COG1566	PFAM secretion protein HlyD family protein
MST16_12640	COG2050	protein possibly involved in aromatic compounds catabolism
MST16_12650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MST16_12655	COG1090	epimerase
MST16_12665	COG3706	GGDEF domain
MST16_12665	COG4251	negative regulation of phosphorylation
MST16_12665	COG2203	Gaf domain
MST16_12665	COG5001	Diguanylate cyclase
MST16_12675	COG0420	3'-5' exonuclease activity
MST16_12705	COG0735	belongs to the Fur family
MST16_12710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MST16_12715	COG2914	Belongs to the UPF0125 (RnfH) family
MST16_12730	COG0121	glutamine amidotransferase
MST16_12740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MST16_12750	COG0210	DNA helicase
MST16_12755	COG2885	chlorophyll binding
MST16_12760	COG0204	Acyl-transferase
MST16_12780	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MST16_12795	COG0583	DNA-binding transcription factor activity
MST16_12800	COG1674	ftsk spoiiie
MST16_12805	COG0492	ferredoxin-NADP+ reductase activity
MST16_12810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MST16_12815	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MST16_12820	COG0456	acetyltransferase
MST16_12835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MST16_12860	COG1981	membrane
MST16_12870	COG1652	LysM domain
MST16_12880	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_12895	COG1399	metal-binding, possibly nucleic acid-binding protein
MST16_12900	COG3101	peptidyl-lysine hydroxylation
MST16_12905	COG0009	L-threonylcarbamoyladenylate synthase
MST16_12920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MST16_12925	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MST16_12940	COG4106	trans-aconitate 2-methyltransferase activity
MST16_12955	COG0596	Alpha beta hydrolase
MST16_12955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MST16_12955	COG2226	methyltransferase
MST16_12960	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MST16_12965	COG2193	ferroxidase activity
MST16_12970	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MST16_12975	COG2801	Transposase and inactivated derivatives
MST16_12985	COG2801	Transposase and inactivated derivatives
MST16_12990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MST16_13010	COG0183	Belongs to the thiolase family
MST16_13025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MST16_13040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MST16_13045	COG2207	Transcriptional regulator
MST16_13055	COG0183	Belongs to the thiolase family
MST16_13060	COG1024	Enoyl-CoA hydratase
MST16_13060	COG1250	3-hydroxyacyl-CoA dehydrogenase
MST16_13075	COG1484	DNA-dependent DNA replication
MST16_13080	COG4584	PFAM Integrase catalytic
MST16_13120	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MST16_13145	COG1272	protein, Hemolysin III
MST16_13150	COG0477	Major facilitator Superfamily
MST16_13155	COG1408	metallophosphoesterase
MST16_13160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MST16_13170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MST16_13200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MST16_13205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MST16_13220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MST16_13225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MST16_13235	COG0625	glutathione transferase activity
MST16_13240	COG2969	positive regulation of protein catabolic process
MST16_13300	COG2199	diguanylate cyclase activity
MST16_13315	COG3300	MHYT domain
MST16_13315	COG5001	Diguanylate cyclase
MST16_13320	COG2885	chlorophyll binding
MST16_13355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MST16_13360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MST16_13375	COG0450	alkyl hydroperoxide reductase
MST16_13395	COG0285	dihydrofolate synthase activity
MST16_13450	COG4206	TonB-dependent receptor
MST16_13455	COG4206	TonB-dependent receptor
MST16_13460	COG2096	Adenosyltransferase
MST16_13480	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MST16_13490	COG2315	Protein conserved in bacteria
MST16_13495	COG2801	Transposase and inactivated derivatives
MST16_13505	COG1113	amino acid transport
MST16_13525	COG0745	RESPONSE REGULATOR receiver
MST16_13530	COG2205	protein histidine kinase activity
MST16_13540	COG1960	acyl-CoA dehydrogenase activity
MST16_13545	COG1960	acyl-CoA dehydrogenase activity
MST16_13585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MST16_13605	COG0438	transferase activity, transferring glycosyl groups
MST16_13610	COG0463	Glycosyl transferase, family 2
MST16_13625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MST16_13645	COG0438	transferase activity, transferring glycosyl groups
MST16_13665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MST16_13670	COG5002	protein histidine kinase activity
MST16_13690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MST16_13700	COG1704	LemA family
MST16_13715	COG1862	Preprotein translocase
MST16_13735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MST16_13755	COG0784	Response regulator, receiver
MST16_13755	COG2205	protein histidine kinase activity
MST16_13755	COG5002	protein histidine kinase activity
MST16_13760	COG1024	Enoyl-CoA hydratase
MST16_13765	COG2084	Dehydrogenase
MST16_13770	COG3622	Belongs to the hyi family
MST16_13785	COG0004	ammonium transporteR
MST16_13805	COG0697	spore germination
MST16_13810	COG2814	Major facilitator Superfamily
MST16_13945	COG4626	Terminase
MST16_13945	COG1802	Transcriptional regulator
MST16_14040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MST16_14045	COG0495	leucyl-tRNA aminoacylation
MST16_14050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MST16_14055	COG2003	Belongs to the UPF0758 family
MST16_14060	COG3781	membrane
MST16_14070	COG0613	PHP domain protein
MST16_14080	COG2350	Protein conserved in bacteria
MST16_14115	COG1607	acyl-coa hydrolase
MST16_14180	COG1183	phosphatidylcholine synthase activity
MST16_14185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MST16_14220	COG1196	nuclear chromosome segregation
MST16_14220	COG0741	lytic transglycosylase activity
MST16_14220	COG0739	heme binding
MST16_14225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MST16_14230	COG1702	phosphate starvation-inducible protein PhoH
MST16_14235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MST16_14275	COG1295	ribonuclease BN
MST16_14295	COG0179	Fumarylacetoacetate (FAA) hydrolase
MST16_14335	COG0557	exoribonuclease II activity
MST16_14340	COG0339	signal peptide processing
MST16_14345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MST16_14355	COG0697	spore germination
MST16_14380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MST16_14385	COG1960	acyl-CoA dehydrogenase activity
MST16_14390	COG2267	carboxylic ester hydrolase activity
MST16_14395	COG2072	flavoprotein involved in K transport
MST16_14400	COG0203	ribosomal protein L17
MST16_14405	COG0202	RNA polymerase activity
MST16_14420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MST16_14445	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MST16_14455	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MST16_14460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MST16_14510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MST16_14525	COG0088	Forms part of the polypeptide exit tunnel
MST16_14530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MST16_14545	COG0626	cystathionine gamma-synthase activity
MST16_14550	COG0433	COG0433 Predicted ATPase
MST16_14560	COG1959	2 iron, 2 sulfur cluster binding
MST16_14580	COG1301	dicarboxylic acid transport
MST16_14585	COG1946	Acyl-CoA thioesterase
MST16_14590	COG2937	Belongs to the GPAT DAPAT family
MST16_14605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MST16_14610	COG1040	competence protein
MST16_14625	COG0598	Magnesium transport protein CorA
MST16_14640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MST16_14645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MST16_14650	COG1127	ABC transporter
MST16_14675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MST16_14680	COG0408	coproporphyrinogen oxidase activity
MST16_14700	COG1960	acyl-CoA dehydrogenase activity
MST16_14720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MST16_14730	COG0534	Mate efflux family protein
MST16_14745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MST16_14750	COG0254	rRNA binding
MST16_14755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MST16_14775	COG2226	methyltransferase
MST16_14790	COG1192	Involved in chromosome partitioning
MST16_14795	COG0628	permease
MST16_14800	COG2032	superoxide dismutase activity
MST16_14805	COG1289	transmembrane transporter activity
MST16_14815	COG2814	Major facilitator Superfamily
MST16_14835	COG3293	Transposase
MST16_14845	COG0277	FAD linked oxidase domain protein
MST16_14850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MST16_14855	COG5006	permease, DMT superfamily
MST16_14860	COG5006	permease, DMT superfamily
MST16_14875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MST16_14880	COG5380	lipid catabolic process
MST16_14885	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MST16_14890	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MST16_14910	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MST16_14915	COG0335	large ribosomal subunit rRNA binding
MST16_14925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MST16_14930	COG0228	four-way junction DNA binding
MST16_14965	COG4969	Belongs to the N-Me-Phe pilin family
MST16_14975	COG0194	GDP metabolic process
MST16_14980	COG1758	RNA polymerase activity
MST16_14985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MST16_15035	COG4969	Belongs to the N-Me-Phe pilin family
MST16_15105	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MST16_15110	COG1704	LemA family
MST16_15120	COG0493	'glutamate synthase
MST16_15125	COG0067	glutamate synthase
MST16_15125	COG0070	glutamate synthase
MST16_15125	COG0069	glutamate synthase activity
MST16_15175	COG2226	methyltransferase
MST16_15185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MST16_15190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MST16_15210	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MST16_15245	COG0675	Transposase, IS605 OrfB family
MST16_15255	COG0488	(ABC) transporter
MST16_15265	COG4221	oxidoreductase activity
MST16_15290	COG0140	phosphoribosyl-ATP diphosphatase activity
MST16_15290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MST16_15305	COG2111	Na H antiporter
MST16_15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MST16_15310	COG1006	Multisubunit Na H antiporter MnhC subunit
MST16_15315	COG0651	ATP synthesis coupled electron transport
MST16_15320	COG1863	multisubunit Na H antiporter MnhE subunit
MST16_15325	COG2212	antiporter activity
MST16_15330	COG1320	monovalent cation:proton antiporter activity
MST16_15340	COG0675	Transposase, IS605 OrfB family
MST16_15350	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MST16_15360	COG0195	Participates in both transcription termination and antitermination
MST16_15365	COG0779	Required for maturation of 30S ribosomal subunits
MST16_15420	COG0237	dephospho-CoA kinase activity
MST16_15430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MST16_15435	COG3123	guanosine phosphorylase activity
MST16_15440	COG0497	DNA recombination
MST16_15455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MST16_15470	COG1289	transmembrane transporter activity
MST16_15485	COG1132	(ABC) transporter
MST16_15495	COG1538	Outer membrane efflux protein
MST16_15505	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MST16_15520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MST16_15525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MST16_15535	COG0772	Belongs to the SEDS family
MST16_15560	COG4974	Belongs to the 'phage' integrase family
MST16_15575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MST16_15585	COG2197	response regulator
MST16_15600	COG0793	Belongs to the peptidase S41A family
MST16_15605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MST16_15610	COG0795	lipopolysaccharide-transporting ATPase activity
MST16_15615	COG0795	lipopolysaccharide-transporting ATPase activity
MST16_15640	COG0586	Pfam SNARE associated Golgi protein
MST16_15655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MST16_15655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MST16_15665	COG0004	ammonium transporteR
MST16_15670	COG0347	Belongs to the P(II) protein family
MST16_15710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MST16_15725	COG0318	PFAM AMP-dependent synthetase and ligase
MST16_15735	COG0477	Major facilitator Superfamily
MST16_15740	COG2860	membrane
MST16_15750	COG1253	flavin adenine dinucleotide binding
MST16_15770	COG2814	Major facilitator Superfamily
MST16_15785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MST16_15790	COG0477	Major facilitator Superfamily
MST16_15865	COG1131	(ABC) transporter
MST16_15870	COG1309	transcriptional regulator
MST16_15900	COG0758	DNA mediated transformation
MST16_15920	COG0386	Belongs to the glutathione peroxidase family
MST16_16015	COG1121	(ABC) transporter
MST16_16020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MST16_16025	COG1280	lysine exporter protein (LysE YggA)
MST16_16030	COG2837	iron assimilation
MST16_16055	COG0436	Aminotransferase
MST16_16060	COG0534	Mate efflux family protein
MST16_16065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MST16_16080	COG3829	transcription factor binding
MST16_16085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST16_16100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST16_16105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MST16_16165	COG3706	GGDEF domain
MST16_16170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MST16_16170	COG0519	Catalyzes the synthesis of GMP from XMP
MST16_16175	COG2259	Doxx family
MST16_16180	COG0586	Pfam SNARE associated Golgi protein
MST16_16195	COG1192	Involved in chromosome partitioning
MST16_16205	COG0271	Belongs to the BolA IbaG family
MST16_16225	COG0281	malic enzyme
MST16_16255	COG1028	Short-chain dehydrogenase reductase Sdr
MST16_16260	COG1309	transcriptional regulator
MST16_16270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MST16_16275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MST16_16280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MST16_16285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MST16_16295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MST16_16345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MST16_16360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MST16_16370	COG0662	Cupin 2, conserved barrel domain protein
MST16_16370	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MST16_16375	COG0297	glycogen (starch) synthase activity
MST16_16390	COG0110	maltose O-acetyltransferase activity
MST16_16420	COG1051	belongs to the nudix hydrolase family
MST16_16425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MST16_16435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MST16_16445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MST16_16455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MST16_16460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MST16_16465	COG0438	transferase activity, transferring glycosyl groups
MST16_16470	COG0438	transferase activity, transferring glycosyl groups
MST16_16475	COG0438	transferase activity, transferring glycosyl groups
MST16_16485	COG0110	maltose O-acetyltransferase activity
MST16_16500	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MST16_16505	COG1596	polysaccharide export
MST16_16540	COG1194	a g-specific adenine glycosylase
MST16_16555	COG2818	Glycosylase
MST16_16560	COG1064	alcohol dehydrogenase
MST16_16585	COG3307	-O-antigen
MST16_16605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MST16_16610	COG1309	transcriptional regulator
MST16_16620	COG2233	PERMEase
MST16_16625	COG0583	DNA-binding transcription factor activity
MST16_16645	COG3077	Addiction module antitoxin, RelB DinJ family
MST16_16670	COG2801	Transposase and inactivated derivatives
MST16_16685	COG0129	dihydroxy-acid dehydratase activity
MST16_16690	COG0129	dihydroxy-acid dehydratase activity
MST16_16700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MST16_16700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MST16_16710	COG0733	neurotransmitter:sodium symporter activity
MST16_16715	COG3738	Protein conserved in bacteria
MST16_16720	COG1012	belongs to the aldehyde dehydrogenase family
MST16_16725	COG2814	Major facilitator Superfamily
MST16_16760	COG4716	Myosin-crossreactive antigen
MST16_16785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MST16_16790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MST16_16795	COG2951	lytic endotransglycosylase activity
MST16_16800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MST16_16810	COG0675	Transposase, IS605 OrfB family
MST16_16820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MST16_16840	COG2388	GCN5-related N-acetyl-transferase
MST16_16845	COG2814	Major facilitator Superfamily
MST16_16850	COG0861	Integral membrane protein TerC family
MST16_16860	COG0402	S-adenosylhomocysteine deaminase activity
MST16_16875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MST16_16880	COG1230	cation diffusion facilitator family transporter
MST16_16905	COG0706	membrane insertase activity
MST16_16910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MST16_16915	COG0594	ribonuclease P activity
MST16_16955	COG1192	Involved in chromosome partitioning
MST16_16960	COG1475	DNA binding
MST16_17015	COG2184	nucleotidyltransferase activity
MST16_17080	COG1683	Conserved Protein
MST16_17115	COG1230	cation diffusion facilitator family transporter
MST16_17125	COG0789	Transcriptional regulator
MST16_17130	COG0582	viral genome integration into host DNA
MST16_17185	COG2076	Multidrug Resistance protein
MST16_17225	COG4974	Belongs to the 'phage' integrase family
MST16_17250	COG3173	Aminoglycoside phosphotransferase
MST16_17275	COG1373	ATPase (AAA superfamily
MST16_17350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MST16_17360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MST16_17390	COG3077	Addiction module antitoxin, RelB DinJ family
MST16_17420	COG3173	Aminoglycoside phosphotransferase
MST16_17425	COG0488	(ABC) transporter