locus-tag	class	description
J4G44_00010	COG1555	photosystem II stabilization
J4G44_00010	COG1596	polysaccharide export
J4G44_00015	COG3956	TIGRFAM MazG family protein
J4G44_00030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4G44_00050	COG1426	Protein conserved in bacteria
J4G44_00070	COG2975	iron-sulfur cluster assembly
J4G44_00110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4G44_00140	COG4206	TonB-dependent receptor
J4G44_00145	COG2096	Adenosyltransferase
J4G44_00160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J4G44_00165	COG2315	Protein conserved in bacteria
J4G44_00180	COG0745	RESPONSE REGULATOR receiver
J4G44_00185	COG2205	protein histidine kinase activity
J4G44_00195	COG1960	acyl-CoA dehydrogenase activity
J4G44_00200	COG1960	acyl-CoA dehydrogenase activity
J4G44_00220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4G44_00235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J4G44_00250	COG1215	transferase activity, transferring glycosyl groups
J4G44_00265	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J4G44_00290	COG0726	polysaccharide deacetylase
J4G44_00315	COG0028	Belongs to the TPP enzyme family
J4G44_00340	COG2703	oxygen carrier activity
J4G44_00345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4G44_00350	COG0577	efflux transmembrane transporter activity
J4G44_00350	COG1136	(ABC) transporter
J4G44_00355	COG1538	Outer membrane efflux protein
J4G44_00360	COG0784	Response regulator, receiver
J4G44_00360	COG2205	protein histidine kinase activity
J4G44_00360	COG5002	protein histidine kinase activity
J4G44_00380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J4G44_00390	COG1704	LemA family
J4G44_00395	COG5001	Diguanylate cyclase
J4G44_00395	COG4251	negative regulation of phosphorylation
J4G44_00395	COG3706	GGDEF domain
J4G44_00395	COG2203	Gaf domain
J4G44_00410	COG1862	Preprotein translocase
J4G44_00430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4G44_00450	COG0675	Transposase, IS605 OrfB family
J4G44_00455	COG5002	protein histidine kinase activity
J4G44_00455	COG2205	protein histidine kinase activity
J4G44_00455	COG0784	Response regulator, receiver
J4G44_00460	COG1024	Enoyl-CoA hydratase
J4G44_00465	COG2084	Dehydrogenase
J4G44_00470	COG3622	Belongs to the hyi family
J4G44_00500	COG2814	Major facilitator Superfamily
J4G44_00510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4G44_00515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4G44_00520	COG0084	hydrolase, TatD family'
J4G44_00535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J4G44_00565	COG2267	carboxylic ester hydrolase activity
J4G44_00580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4G44_00585	COG0280	phosphate acetyltransferase
J4G44_00585	COG0857	belongs to the CobB CobQ family
J4G44_00600	COG1476	TRANSCRIPTIONal
J4G44_00605	COG2890	protein-(glutamine-N5) methyltransferase activity
J4G44_00610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J4G44_00610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J4G44_00625	COG0740	serine-type endopeptidase activity
J4G44_00635	COG4771	TonB-dependent receptor
J4G44_00640	COG4774	siderophore transport
J4G44_00645	COG3128	pkhd-type hydroxylase
J4G44_00655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4G44_00660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4G44_00665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4G44_00665	COG2813	Specifically methylates the guanine in position
J4G44_00680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4G44_00720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4G44_00745	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4G44_00775	COG0557	exoribonuclease II activity
J4G44_00785	COG0339	signal peptide processing
J4G44_00790	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J4G44_00825	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J4G44_00830	COG1960	acyl-CoA dehydrogenase activity
J4G44_00835	COG2072	flavoprotein involved in K transport
J4G44_00840	COG0203	ribosomal protein L17
J4G44_00850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J4G44_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4G44_00885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J4G44_00895	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4G44_00900	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4G44_00910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J4G44_00940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J4G44_00950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4G44_00965	COG0088	Forms part of the polypeptide exit tunnel
J4G44_00990	COG0433	COG0433 Predicted ATPase
J4G44_01000	COG1959	2 iron, 2 sulfur cluster binding
J4G44_01015	COG1301	dicarboxylic acid transport
J4G44_01020	COG1946	Acyl-CoA thioesterase
J4G44_01025	COG2937	Belongs to the GPAT DAPAT family
J4G44_01045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4G44_01050	COG1040	competence protein
J4G44_01065	COG0598	Magnesium transport protein CorA
J4G44_01075	COG2854	intermembrane phospholipid transfer
J4G44_01080	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J4G44_01085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J4G44_01090	COG1127	ABC transporter
J4G44_01095	COG0513	Belongs to the DEAD box helicase family
J4G44_01115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4G44_01120	COG0408	coproporphyrinogen oxidase activity
J4G44_01140	COG1960	acyl-CoA dehydrogenase activity
J4G44_01145	COG2318	DinB family
J4G44_01160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J4G44_01170	COG0534	Mate efflux family protein
J4G44_01175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4G44_01190	COG0254	rRNA binding
J4G44_01195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4G44_01220	COG1192	Involved in chromosome partitioning
J4G44_01225	COG0628	permease
J4G44_01230	COG2032	superoxide dismutase activity
J4G44_01235	COG2814	Major facilitator Superfamily
J4G44_01255	COG0277	FAD linked oxidase domain protein
J4G44_01260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4G44_01275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J4G44_01280	COG5380	lipid catabolic process
J4G44_01285	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J4G44_01295	COG0335	large ribosomal subunit rRNA binding
J4G44_01305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J4G44_01310	COG0228	four-way junction DNA binding
J4G44_01355	COG0194	GDP metabolic process
J4G44_01360	COG1758	RNA polymerase activity
J4G44_01365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4G44_01390	COG3609	addiction module antidote protein, CC2985 family
J4G44_01395	COG3307	-O-antigen
J4G44_01410	COG4969	Belongs to the N-Me-Phe pilin family
J4G44_01420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J4G44_01425	COG1704	LemA family
J4G44_01430	COG0493	'glutamate synthase
J4G44_01435	COG0070	glutamate synthase
J4G44_01435	COG0069	glutamate synthase activity
J4G44_01435	COG0067	glutamate synthase
J4G44_01485	COG2226	methyltransferase
J4G44_01490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4G44_01495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4G44_01500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4G44_01515	COG0275	rRNA processing
J4G44_01520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J4G44_01530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4G44_01550	COG0488	(ABC) transporter
J4G44_01560	COG4221	oxidoreductase activity
J4G44_01590	COG0427	acetyl-CoA hydrolase
J4G44_01625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4G44_01635	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4G44_01645	COG0697	spore germination
J4G44_01660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4G44_01710	COG3158	transport of potassium into the cell
J4G44_01740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4G44_01745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J4G44_01750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J4G44_01760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4G44_01810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4G44_01815	COG0668	transmembrane transport
J4G44_01825	COG1519	Transferase
J4G44_01830	COG1902	pentaerythritol trinitrate reductase activity
J4G44_01855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J4G44_01880	COG0426	domain, Protein
J4G44_01880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4G44_01885	COG2119	membrane
J4G44_01910	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J4G44_01915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4G44_01925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J4G44_01945	COG0189	ligase activity
J4G44_01980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4G44_01985	COG0708	Exodeoxyribonuclease III
J4G44_01990	COG1393	Belongs to the ArsC family
J4G44_02005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4G44_02050	COG0471	metal ion transport
J4G44_02065	COG3150	esterase
J4G44_02080	COG2918	glutathione biosynthetic process
J4G44_02095	COG2733	membrane
J4G44_02100	COG0436	Aminotransferase
J4G44_02105	COG0534	Mate efflux family protein
J4G44_02165	COG0560	Phosphoserine phosphatase
J4G44_02165	COG3830	Belongs to the UPF0237 family
J4G44_02180	COG1335	isochorismatase
J4G44_02190	COG2814	Major facilitator Superfamily
J4G44_02195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4G44_02205	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4G44_02215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J4G44_02220	COG2983	Belongs to the UPF0260 family
J4G44_02225	COG5487	UPF0391 membrane protein
J4G44_02240	COG1194	a g-specific adenine glycosylase
J4G44_02255	COG2818	Glycosylase
J4G44_02260	COG1064	alcohol dehydrogenase
J4G44_02280	COG3023	N-Acetylmuramoyl-L-alanine amidase
J4G44_02295	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4G44_02310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J4G44_02315	COG0546	phosphoglycolate phosphatase activity
J4G44_02320	COG1028	Short-chain dehydrogenase reductase Sdr
J4G44_02325	COG0431	NADPH-dependent FMN reductase
J4G44_02355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4G44_02360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4G44_02365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4G44_02370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4G44_02375	COG1116	anion transmembrane transporter activity
J4G44_02380	COG1309	transcriptional regulator
J4G44_02390	COG0196	riboflavin kinase activity
J4G44_02395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J4G44_02405	COG1047	Peptidyl-prolyl cis-trans
J4G44_02410	COG2133	pyrroloquinoline quinone binding
J4G44_02415	COG2814	Major facilitator Superfamily
J4G44_02445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J4G44_02455	COG0675	Transposase, IS605 OrfB family
J4G44_02465	COG0657	acetylesterase activity
J4G44_02475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4G44_02495	COG2951	lytic endotransglycosylase activity
J4G44_02500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J4G44_02515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4G44_02520	COG1063	alcohol dehydrogenase
J4G44_02530	COG0861	Integral membrane protein TerC family
J4G44_02535	COG0402	S-adenosylhomocysteine deaminase activity
J4G44_02555	COG1230	cation diffusion facilitator family transporter
J4G44_02580	COG0706	membrane insertase activity
J4G44_02585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J4G44_02590	COG0594	ribonuclease P activity
J4G44_02605	COG0592	DNA-directed DNA polymerase activity
J4G44_02615	COG0187	DNA topoisomerase II activity
J4G44_02625	COG0488	(ABC) transporter
J4G44_02645	COG0316	Belongs to the HesB IscA family
J4G44_02650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J4G44_02655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4G44_02695	COG1012	belongs to the aldehyde dehydrogenase family
J4G44_02700	COG0733	neurotransmitter:sodium symporter activity
J4G44_02710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J4G44_02720	COG0129	dihydroxy-acid dehydratase activity
J4G44_02725	COG0129	dihydroxy-acid dehydratase activity
J4G44_02750	COG2233	PERMEase
J4G44_02765	COG1309	transcriptional regulator
J4G44_02795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J4G44_02810	COG2852	Protein conserved in bacteria
J4G44_02830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4G44_02840	COG5039	Polysaccharide pyruvyl transferase
J4G44_02845	COG1216	Glycosyl transferase, family 2
J4G44_02860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J4G44_02865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4G44_02880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4G44_02895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J4G44_02910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4G44_02925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4G44_02930	COG3550	peptidyl-serine autophosphorylation
J4G44_02950	COG0271	Belongs to the BolA IbaG family
J4G44_02955	COG3094	Invasion gene expression up-regulator, SirB
J4G44_02960	COG1192	Involved in chromosome partitioning
J4G44_02975	COG0586	Pfam SNARE associated Golgi protein
J4G44_02980	COG2259	Doxx family
J4G44_02985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J4G44_02985	COG0519	Catalyzes the synthesis of GMP from XMP
J4G44_03030	COG0281	malic enzyme
J4G44_03040	COG0784	Response regulator, receiver
J4G44_03040	COG2205	protein histidine kinase activity
J4G44_03045	COG3162	membrane
J4G44_03050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4G44_03080	COG0351	phosphomethylpyrimidine kinase
J4G44_03080	COG0352	thiamine-phosphate diphosphorylase activity
J4G44_03080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4G44_03090	COG2814	Major facilitator Superfamily
J4G44_03145	COG2826	transposase and inactivated derivatives, IS30 family
J4G44_03170	COG2837	iron assimilation
J4G44_03185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4G44_03190	COG1121	(ABC) transporter
J4G44_03240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4G44_03255	COG0386	Belongs to the glutathione peroxidase family
J4G44_03260	COG0697	spore germination
J4G44_03275	COG0009	L-threonylcarbamoyladenylate synthase
J4G44_03280	COG0758	DNA mediated transformation
J4G44_03330	COG2814	Major facilitator Superfamily
J4G44_03335	COG2814	Major facilitator Superfamily
J4G44_03355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4G44_03390	COG1253	flavin adenine dinucleotide binding
J4G44_03395	COG3012	SEC-C Motif Domain Protein
J4G44_03400	COG2860	membrane
J4G44_03405	COG0477	Major facilitator Superfamily
J4G44_03415	COG0318	PFAM AMP-dependent synthetase and ligase
J4G44_03430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4G44_03450	COG0606	chelatase, subunit chli
J4G44_03460	COG0347	Belongs to the P(II) protein family
J4G44_03465	COG0004	ammonium transporteR
J4G44_03475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4G44_03475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J4G44_03490	COG0586	Pfam SNARE associated Golgi protein
J4G44_03515	COG0795	lipopolysaccharide-transporting ATPase activity
J4G44_03520	COG0795	lipopolysaccharide-transporting ATPase activity
J4G44_03525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J4G44_03530	COG0793	Belongs to the peptidase S41A family
J4G44_03545	COG2197	response regulator
J4G44_03555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4G44_03565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4G44_03570	COG4974	Belongs to the 'phage' integrase family
J4G44_03595	COG0772	Belongs to the SEDS family
J4G44_03605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4G44_03610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J4G44_03615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J4G44_03620	COG0494	nUDIX hydrolase
J4G44_03635	COG1538	Outer membrane efflux protein
J4G44_03650	COG0165	Argininosuccinate lyase
J4G44_03655	COG3275	phosphorelay sensor kinase activity
J4G44_03665	COG0181	hydroxymethylbilane synthase activity
J4G44_03685	COG0824	Thioesterase
J4G44_03770	COG0081	regulation of translation
J4G44_03785	COG0085	RNA polymerase activity
J4G44_03820	COG2056	Na+-H+ antiporter family
J4G44_03825	COG3047	cAMP biosynthetic process
J4G44_03835	COG0326	Molecular chaperone. Has ATPase activity
J4G44_03865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J4G44_03885	COG1024	Enoyl-CoA hydratase
J4G44_03885	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4G44_03905	COG0322	excinuclease ABC activity
J4G44_03915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4G44_03920	COG1132	(ABC) transporter
J4G44_03935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4G44_03965	COG0497	DNA recombination
J4G44_03970	COG3123	guanosine phosphorylase activity
J4G44_03975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4G44_03985	COG0237	dephospho-CoA kinase activity
J4G44_04035	COG0779	Required for maturation of 30S ribosomal subunits
J4G44_04040	COG0195	Participates in both transcription termination and antitermination
J4G44_04045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J4G44_04050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J4G44_04055	COG1320	monovalent cation:proton antiporter activity
J4G44_04060	COG2212	antiporter activity
J4G44_04065	COG1863	multisubunit Na H antiporter MnhE subunit
J4G44_04070	COG0651	ATP synthesis coupled electron transport
J4G44_04075	COG1006	Multisubunit Na H antiporter MnhC subunit
J4G44_04080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4G44_04080	COG2111	Na H antiporter
J4G44_04105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J4G44_04115	COG2226	methyltransferase
J4G44_04135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J4G44_04140	COG1074	ATP-dependent DNA helicase activity
J4G44_04145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4G44_04185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J4G44_04195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J4G44_04210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J4G44_04215	COG4535	Mg2 and Co2 transporter CorC
J4G44_04240	COG0644	oxidoreductase
J4G44_04240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J4G44_04250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4G44_04265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4G44_04270	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J4G44_04280	COG0493	'glutamate synthase
J4G44_04290	COG2226	methyltransferase
J4G44_04320	COG0751	glycine-tRNA ligase activity
J4G44_04330	COG0517	IMP dehydrogenase activity
J4G44_04330	COG0617	tRNA 3'-terminal CCA addition
J4G44_04330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J4G44_04335	COG1983	PspC domain protein
J4G44_04360	COG0318	PFAM AMP-dependent synthetase and ligase
J4G44_04365	COG1530	ribonuclease E activity
J4G44_04375	COG0546	phosphoglycolate phosphatase activity
J4G44_04380	COG3971	2-oxopent-4-enoate hydratase activity
J4G44_04385	COG4569	acetaldehyde dehydrogenase (acetylating) activity
J4G44_04410	COG0583	DNA-binding transcription factor activity
J4G44_04415	COG4638	Rieske (2fe-2S)
J4G44_04430	COG1028	Short-chain dehydrogenase reductase Sdr
J4G44_04435	COG3384	dioxygenase
J4G44_04440	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4G44_04455	COG0753	catalase activity
J4G44_04465	COG1960	acyl-CoA dehydrogenase activity
J4G44_04500	COG0583	DNA-binding transcription factor activity
J4G44_04515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J4G44_04530	COG0473	3-isopropylmalate dehydrogenase activity
J4G44_04550	COG0101	tRNA pseudouridine synthase activity
J4G44_04555	COG0252	asparaginase activity
J4G44_04585	COG1560	Kdo2-lipid A biosynthetic process
J4G44_04590	COG0488	(ABC) transporter
J4G44_04595	COG2900	Belongs to the SlyX family
J4G44_04625	COG0724	RNA recognition motif
J4G44_04640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J4G44_04640	COG4651	solute:proton antiporter activity
J4G44_04665	COG0788	formyltetrahydrofolate deformylase activity
J4G44_04690	COG1295	ribonuclease BN
J4G44_04730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4G44_04735	COG1702	phosphate starvation-inducible protein PhoH
J4G44_04740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4G44_04745	COG0739	heme binding
J4G44_04745	COG0741	lytic transglycosylase activity
J4G44_04745	COG1196	nuclear chromosome segregation
J4G44_04760	COG2391	methyltransferase activity
J4G44_04785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J4G44_04790	COG1183	phosphatidylcholine synthase activity
J4G44_04825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4G44_04855	COG1607	acyl-coa hydrolase
J4G44_04885	COG2350	Protein conserved in bacteria
J4G44_04900	COG3781	membrane
J4G44_04910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J4G44_04920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J4G44_04930	COG1162	GTPase activity
J4G44_04935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J4G44_04955	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J4G44_04960	COG0285	dihydrofolate synthase activity
J4G44_04970	COG0450	alkyl hydroperoxide reductase
J4G44_04985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J4G44_04990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J4G44_05015	COG2885	chlorophyll binding
J4G44_05020	COG5001	Diguanylate cyclase
J4G44_05020	COG3300	MHYT domain
J4G44_05060	COG2969	positive regulation of protein catabolic process
J4G44_05065	COG0625	glutathione transferase activity
J4G44_05070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J4G44_05090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4G44_05095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J4G44_05125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4G44_05135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4G44_05140	COG1408	metallophosphoesterase
J4G44_05145	COG0477	Major facilitator Superfamily
J4G44_05150	COG1272	protein, Hemolysin III
J4G44_05170	COG1250	3-hydroxyacyl-CoA dehydrogenase
J4G44_05170	COG1024	Enoyl-CoA hydratase
J4G44_05175	COG0183	Belongs to the thiolase family
J4G44_05180	COG2207	Transcriptional regulator
J4G44_05185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J4G44_05190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4G44_05205	COG0183	Belongs to the thiolase family
J4G44_05220	COG0833	amino acid
J4G44_05230	COG2233	PERMEase
J4G44_05235	COG1217	gtp-binding protein TYPA
J4G44_05240	COG1970	mechanosensitive ion channel activity
J4G44_05245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4G44_05255	COG1902	pentaerythritol trinitrate reductase activity
J4G44_05265	COG0675	Transposase, IS605 OrfB family
J4G44_05280	COG0354	folic acid binding
J4G44_05285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J4G44_05290	COG4456	Virulence-associated protein
J4G44_05295	COG1487	ribonuclease activity
J4G44_05320	COG0564	pseudouridine synthase activity
J4G44_05335	COG3189	MarR family transcriptional regulator
J4G44_05340	COG2824	Alkylphosphonate utilization operon protein PhnA
J4G44_05345	COG3422	double-strand break repair
J4G44_05355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4G44_05365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J4G44_05380	COG0730	response to heat
J4G44_05390	COG1196	nuclear chromosome segregation
J4G44_05395	COG3115	cell septum assembly
J4G44_05400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4G44_05405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J4G44_05410	COG2193	ferroxidase activity
J4G44_05415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4G44_05415	COG2226	methyltransferase
J4G44_05415	COG0596	Alpha beta hydrolase
J4G44_05430	COG4106	trans-aconitate 2-methyltransferase activity
J4G44_05445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J4G44_05450	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J4G44_05460	COG0009	L-threonylcarbamoyladenylate synthase
J4G44_05465	COG3101	peptidyl-lysine hydroxylation
J4G44_05470	COG1399	metal-binding, possibly nucleic acid-binding protein
J4G44_05485	COG1028	Short-chain dehydrogenase reductase Sdr
J4G44_05495	COG1652	LysM domain
J4G44_05510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4G44_05520	COG0745	RESPONSE REGULATOR receiver
J4G44_05525	COG2205	protein histidine kinase activity
J4G44_05530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4G44_05545	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4G44_05560	COG2323	membrane
J4G44_05565	COG2852	Protein conserved in bacteria
J4G44_05575	COG2826	transposase and inactivated derivatives, IS30 family
J4G44_05585	COG0525	valine-tRNA ligase activity
J4G44_05595	COG1028	Short-chain dehydrogenase reductase Sdr
J4G44_05610	COG0393	Putative heavy-metal-binding
J4G44_05615	COG0393	Putative heavy-metal-binding
J4G44_05620	COG1538	Outer membrane efflux protein
J4G44_05625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4G44_05630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4G44_05635	COG0671	phosphoesterase, PA-phosphatase related
J4G44_05660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J4G44_05670	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J4G44_05675	COG1648	precorrin-2 dehydrogenase activity
J4G44_05675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J4G44_05680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4G44_05685	COG0531	amino acid
J4G44_05700	COG0321	lipoyl(octanoyl) transferase activity
J4G44_05735	COG0586	Pfam SNARE associated Golgi protein
J4G44_05745	COG1054	Belongs to the UPF0176 family
J4G44_05770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J4G44_05800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J4G44_05810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J4G44_05815	COG0358	DNA primase activity
J4G44_05825	COG0564	pseudouridine synthase activity
J4G44_05850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4G44_05875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J4G44_05875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4G44_05895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J4G44_05900	COG1053	succinate dehydrogenase
J4G44_05905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4G44_05920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4G44_05940	COG0726	polysaccharide deacetylase
J4G44_05940	COG1649	PFAM Uncharacterised BCR, COG1649
J4G44_05945	COG1215	transferase activity, transferring glycosyl groups
J4G44_05955	COG0726	polysaccharide deacetylase
J4G44_05955	COG1649	PFAM Uncharacterised BCR, COG1649
J4G44_05965	COG2354	Protein conserved in bacteria
J4G44_05970	COG2321	neutral zinc metallopeptidase
J4G44_05975	COG3695	enzyme binding
J4G44_05980	COG0589	response to stress
J4G44_06005	COG0505	Belongs to the CarA family
J4G44_06030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4G44_06035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4G44_06075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4G44_06095	COG1597	lipid kinase activity
J4G44_06100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J4G44_06110	COG0459	protein refolding
J4G44_06130	COG2239	Acts as a magnesium transporter
J4G44_06140	COG0501	Belongs to the peptidase M48B family
J4G44_06145	COG1196	nuclear chromosome segregation
J4G44_06145	COG0741	lytic transglycosylase activity
J4G44_06145	COG0739	heme binding
J4G44_06165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4G44_06190	COG0306	phosphate transporter
J4G44_06235	COG4181	ATPase activity
J4G44_06240	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J4G44_06245	COG0705	Rhomboid family
J4G44_06245	COG0457	Tetratricopeptide repeat
J4G44_06250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4G44_06265	COG0583	DNA-binding transcription factor activity
J4G44_06270	COG2267	carboxylic ester hydrolase activity
J4G44_06275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J4G44_06280	COG1773	rubredoxin
J4G44_06285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4G44_06300	COG3093	addiction module antidote protein HigA
J4G44_06305	COG3549	Plasmid maintenance system killer
J4G44_06315	COG0175	sulfate reduction
J4G44_06385	COG2871	sodium ion transport
J4G44_06400	COG2072	flavoprotein involved in K transport
J4G44_06405	COG1741	Belongs to the pirin family
J4G44_06420	COG3739	integral membrane protein
J4G44_06435	COG3706	GGDEF domain
J4G44_06440	COG0302	gtp cyclohydrolase
J4G44_06455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J4G44_06460	COG0512	Glutamine amidotransferase of anthranilate synthase
J4G44_06465	COG0174	glutamine synthetase
J4G44_06475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J4G44_06510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J4G44_06515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4G44_06520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4G44_06535	COG1115	amino acid carrier protein
J4G44_06545	COG0019	diaminopimelate decarboxylase activity
J4G44_06560	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J4G44_06600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4G44_06640	COG1671	Belongs to the UPF0178 family
J4G44_06655	COG4591	ABC-type transport system involved in lipoprotein release permease component
J4G44_06660	COG1136	(ABC) transporter
J4G44_06670	COG0658	competence protein
J4G44_06670	COG2333	competence protein COMEC
J4G44_06690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4G44_06695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4G44_06700	COG0628	permease
J4G44_06705	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J4G44_06735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4G44_06755	COG0823	Involved in the tonB-independent uptake of proteins
J4G44_06775	COG0824	Thioesterase
J4G44_06785	COG2255	four-way junction helicase activity
J4G44_06790	COG0632	four-way junction helicase activity
J4G44_06805	COG0778	Nitroreductase
J4G44_06810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4G44_06815	COG1051	belongs to the nudix hydrolase family
J4G44_06815	COG1056	cytidyltransferase-related domain
J4G44_06820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J4G44_06830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J4G44_06845	COG4625	pathogenesis
J4G44_06855	COG0583	DNA-binding transcription factor activity
J4G44_06860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J4G44_06865	COG4208	sulfate ABC transporter
J4G44_06880	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J4G44_06890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J4G44_06905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4G44_06915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J4G44_06940	COG0571	ribonuclease III activity
J4G44_06945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4G44_06960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J4G44_06985	COG0436	Aminotransferase
J4G44_07000	COG0556	nucleotide-excision repair
J4G44_07020	COG1733	regulation of RNA biosynthetic process
J4G44_07025	COG2814	Major facilitator Superfamily
J4G44_07040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J4G44_07050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J4G44_07055	COG0076	glutamate decarboxylase activity
J4G44_07065	COG0573	inorganic phosphate transmembrane transporter activity
J4G44_07075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4G44_07085	COG0616	signal peptide processing
J4G44_07105	COG2915	High frequency lysogenization protein hflD homolog
J4G44_07125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J4G44_07130	COG1686	Belongs to the peptidase S11 family
J4G44_07155	COG0583	DNA-binding transcription factor activity
J4G44_07160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4G44_07165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J4G44_07170	COG1067	ATP-dependent peptidase activity
J4G44_07205	COG1509	lysine 2,3-aminomutase activity
J4G44_07210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4G44_07215	COG1966	Carbon starvation protein
J4G44_07220	COG2879	small protein
J4G44_07225	COG0714	Associated with various cellular activities
J4G44_07255	COG2252	PERMEase
J4G44_07260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4G44_07275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J4G44_07285	COG0527	aspartate kinase activity
J4G44_07290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4G44_07295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4G44_07310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4G44_07325	COG0667	Aldo Keto reductase
J4G44_07335	COG1765	OsmC-like protein
J4G44_07360	COG0540	Belongs to the ATCase OTCase family
J4G44_07370	COG2885	chlorophyll binding
J4G44_07370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J4G44_07375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J4G44_07390	COG4770	biotin carboxylase activity
J4G44_07395	COG1024	Enoyl-CoA hydratase
J4G44_07400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4G44_07405	COG1960	acyl-CoA dehydrogenase activity
J4G44_07410	COG1309	transcriptional regulator
J4G44_07415	COG0318	PFAM AMP-dependent synthetase and ligase
J4G44_07440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4G44_07445	COG0659	secondary active sulfate transmembrane transporter activity
J4G44_07465	COG2363	Small membrane protein
J4G44_07480	COG1278	Cold shock
J4G44_07485	COG0513	Belongs to the DEAD box helicase family
J4G44_07495	COG0778	Nitroreductase
J4G44_07520	COG0167	dihydroorotate dehydrogenase activity
J4G44_07525	COG1286	toxin biosynthetic process
J4G44_07565	COG1610	YqeY-like protein
J4G44_07635	COG0436	Aminotransferase
J4G44_07640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4G44_07645	COG0386	Belongs to the glutathione peroxidase family
J4G44_07655	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J4G44_07660	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J4G44_07670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J4G44_07680	COG0012	GTP binding
J4G44_07735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J4G44_07765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J4G44_07765	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J4G44_07805	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4G44_07810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J4G44_07825	COG2353	YceI-like domain
J4G44_07845	COG1454	alcohol dehydrogenase
J4G44_07855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4G44_07860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J4G44_07865	COG0583	DNA-binding transcription factor activity
J4G44_07870	COG2807	transmembrane transport
J4G44_07875	COG2707	UPF0756 membrane protein
J4G44_07905	COG0802	atpase or kinase
J4G44_07910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J4G44_07920	COG1923	regulation of RNA biosynthetic process
J4G44_07965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4G44_07980	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J4G44_07990	COG1192	Involved in chromosome partitioning
J4G44_07995	COG1475	DNA binding
J4G44_08000	COG0811	peptide transport
J4G44_08010	COG1132	(ABC) transporter
J4G44_08015	COG1663	tetraacyldisaccharide 4'-kinase activity
J4G44_08035	COG0084	hydrolase, TatD family'
J4G44_08070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4G44_08115	COG2431	L-lysine efflux transmembrane transporter activity
J4G44_08130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J4G44_08135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J4G44_08155	COG1253	flavin adenine dinucleotide binding
J4G44_08175	COG1114	Component of the transport system for branched-chain amino acids
J4G44_08180	COG0024	Methionine aminopeptidase
J4G44_08185	COG0583	DNA-binding transcription factor activity
J4G44_08190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4G44_08205	COG3852	Histidine kinase
J4G44_08225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4G44_08230	COG0575	Belongs to the CDS family
J4G44_08245	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4G44_08265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4G44_08280	COG2137	regulation of response to DNA damage stimulus
J4G44_08290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J4G44_08295	COG1011	Hydrolase
J4G44_08325	COG0268	Binds directly to 16S ribosomal RNA
J4G44_08330	COG0702	epimerase
J4G44_08335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J4G44_08350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J4G44_08380	COG0316	Belongs to the HesB IscA family
J4G44_08385	COG0822	iron-sulfur transferase activity
J4G44_08415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J4G44_08440	COG0537	adenosine 5'-monophosphoramidase activity
J4G44_08470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4G44_08490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4G44_08500	COG0133	tryptophan synthase activity
J4G44_08505	COG0517	IMP dehydrogenase activity
J4G44_08535	COG0612	Peptidase, M16
J4G44_08540	COG0552	protein localization to endoplasmic reticulum
J4G44_08590	COG1283	sodium-dependent phosphate transmembrane transporter activity
J4G44_08595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4G44_08625	COG0596	Alpha beta hydrolase
J4G44_08635	COG0511	ligase activity, forming carbon-carbon bonds
J4G44_08640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J4G44_08645	COG0642	Histidine kinase
J4G44_08660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4G44_08675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J4G44_08680	COG1944	ATP diphosphatase activity
J4G44_08690	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
J4G44_08695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4G44_08710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J4G44_08715	COG2801	Transposase and inactivated derivatives
J4G44_08725	COG1132	(ABC) transporter
J4G44_08740	COG2814	Major facilitator Superfamily
J4G44_08750	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J4G44_08755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4G44_08795	COG1960	acyl-CoA dehydrogenase activity
J4G44_08825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4G44_08830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J4G44_08875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4G44_08885	COG2814	Major facilitator Superfamily
J4G44_08890	COG0583	DNA-binding transcription factor activity
J4G44_08895	COG4948	Mandelate Racemase Muconate Lactonizing
J4G44_08900	COG4829	muconolactone delta-isomerase
J4G44_08910	COG4638	Rieske (2fe-2S)
J4G44_08915	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J4G44_08920	COG0633	Ferredoxin
J4G44_08920	COG0543	2 iron, 2 sulfur cluster binding
J4G44_08925	COG1028	Short-chain dehydrogenase reductase Sdr
J4G44_08930	COG3135	benzoate transporter
J4G44_08935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J4G44_08940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J4G44_08945	COG0183	Belongs to the thiolase family
J4G44_08950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4G44_08955	COG0183	Belongs to the thiolase family
J4G44_08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J4G44_08970	COG2937	Belongs to the GPAT DAPAT family
J4G44_08975	COG0640	Transcriptional regulator
J4G44_08990	COG3619	membrane
J4G44_08995	COG3122	Protein conserved in bacteria
J4G44_09000	COG0668	transmembrane transport
J4G44_09010	COG3706	GGDEF domain
J4G44_09020	COG2814	Major facilitator Superfamily
J4G44_09070	COG1546	Belongs to the CinA family
J4G44_09070	COG1058	Belongs to the CinA family
J4G44_09085	COG0372	Belongs to the citrate synthase family
J4G44_09115	COG0542	response to heat
J4G44_09120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J4G44_09140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J4G44_09150	COG0569	domain protein
J4G44_09155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4G44_09175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4G44_09185	COG1585	Membrane protein implicated in regulation of membrane protease activity
J4G44_09200	COG1294	oxidase, subunit
J4G44_09205	COG4890	Cyd operon protein YbgT
J4G44_09240	COG1960	acyl-CoA dehydrogenase activity
J4G44_09245	COG1960	acyl-CoA dehydrogenase activity
J4G44_09260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4G44_09265	COG2207	Transcriptional regulator
J4G44_09270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4G44_09275	COG0730	response to heat
J4G44_09280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J4G44_09305	COG0772	Belongs to the SEDS family
J4G44_09315	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J4G44_09320	COG0148	phosphopyruvate hydratase activity
J4G44_09350	COG1902	pentaerythritol trinitrate reductase activity
J4G44_09350	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4G44_09360	COG2267	carboxylic ester hydrolase activity
J4G44_09365	COG1960	acyl-CoA dehydrogenase activity
J4G44_09370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J4G44_09375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4G44_09400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4G44_09410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J4G44_09420	COG0778	Nitroreductase
J4G44_09445	COG0126	phosphoglycerate kinase activity
J4G44_09455	COG0424	maF-like protein
J4G44_09480	COG2850	peptidyl-arginine hydroxylation
J4G44_09485	COG4585	Histidine kinase
J4G44_09490	COG2197	response regulator
J4G44_09510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4G44_09515	COG1454	alcohol dehydrogenase
J4G44_09520	COG0824	Thioesterase
J4G44_09525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4G44_09530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J4G44_09545	COG0183	Belongs to the thiolase family
J4G44_09560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4G44_09570	COG3135	benzoate transporter
J4G44_09580	COG0589	response to stress
J4G44_09585	COG0589	response to stress
J4G44_09595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4G44_09600	COG0308	aminopeptidase N
J4G44_09635	COG0729	surface antigen
J4G44_09640	COG0477	Major facilitator Superfamily
J4G44_09655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J4G44_09665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J4G44_09675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J4G44_09680	COG1960	acyl-CoA dehydrogenase activity
J4G44_09700	COG3781	membrane
J4G44_09705	COG2890	protein-(glutamine-N5) methyltransferase activity
J4G44_09710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4G44_09725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J4G44_09750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J4G44_09755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J4G44_09760	COG1845	cytochrome c oxidase, subunit III
J4G44_09765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J4G44_09775	COG0360	Binds together with S18 to 16S ribosomal RNA
J4G44_09780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J4G44_09790	COG0305	Participates in initiation and elongation during chromosome replication
J4G44_09800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4G44_09820	COG0183	Belongs to the thiolase family
J4G44_09865	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J4G44_09870	COG0138	bifunctional purine biosynthesis protein purh
J4G44_09875	COG0151	Belongs to the GarS family
J4G44_09880	COG1464	Belongs to the NlpA lipoprotein family
J4G44_09885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4G44_09890	COG2011	ABC-type metal ion transport system permease component
J4G44_09930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4G44_09955	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J4G44_09965	COG4122	O-methyltransferase activity
J4G44_09985	COG1137	ATPase activity
J4G44_09990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J4G44_10000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J4G44_10005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J4G44_10005	COG0517	IMP dehydrogenase activity
J4G44_10025	COG1643	Atp-dependent helicase
J4G44_10085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J4G44_10085	COG1017	nitric oxide dioxygenase activity
J4G44_10115	COG0352	thiamine-phosphate diphosphorylase activity
J4G44_10150	COG0612	Peptidase, M16
J4G44_10170	COG1686	Belongs to the peptidase S11 family
J4G44_10175	COG1047	Peptidyl-prolyl cis-trans
J4G44_10180	COG0415	Belongs to the DNA photolyase family
J4G44_10200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J4G44_10205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J4G44_10215	COG1960	acyl-CoA dehydrogenase activity
J4G44_10225	COG3139	Protein of unknown function (DUF1315)
J4G44_10230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4G44_10235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4G44_10245	COG0352	thiamine-phosphate diphosphorylase activity
J4G44_10255	COG0642	Histidine kinase
J4G44_10270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J4G44_10280	COG1720	tRNA m6t6A37 methyltransferase activity
J4G44_10305	COG0789	Transcriptional regulator
J4G44_10310	COG0431	NADPH-dependent FMN reductase
J4G44_10315	COG0798	PFAM Bile acid sodium symporter
J4G44_10320	COG0640	Transcriptional regulator
J4G44_10330	COG0826	peptidase U32
J4G44_10335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J4G44_10340	COG3634	alkyl hydroperoxide reductase activity
J4G44_10360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4G44_10400	COG3177	Filamentation induced by cAMP protein fic
J4G44_10420	COG1222	aaa ATPase
J4G44_10640	COG5377	YqaJ viral recombinase family
J4G44_10670	COG0582	viral genome integration into host DNA
J4G44_10680	COG1131	(ABC) transporter
J4G44_10685	COG0842	Transport permease protein
J4G44_10700	COG2951	lytic endotransglycosylase activity
J4G44_10725	COG0052	Belongs to the universal ribosomal protein uS2 family
J4G44_10730	COG0024	Methionine aminopeptidase
J4G44_10750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4G44_10755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4G44_10770	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J4G44_10780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J4G44_10785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J4G44_10790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J4G44_10800	COG0280	phosphate acetyltransferase
J4G44_10800	COG0281	malic enzyme
J4G44_10810	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J4G44_10820	COG0047	phosphoribosylformylglycinamidine synthase activity
J4G44_10820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4G44_10825	COG2885	chlorophyll binding
J4G44_10850	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4G44_10850	COG1902	pentaerythritol trinitrate reductase activity
J4G44_10860	COG4251	negative regulation of phosphorylation
J4G44_10860	COG2203	Gaf domain
J4G44_10860	COG5001	Diguanylate cyclase
J4G44_10860	COG3706	GGDEF domain
J4G44_10865	COG0418	dihydroorotase activity
J4G44_10870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4G44_10885	COG0833	amino acid
J4G44_10915	COG4172	Belongs to the ABC transporter superfamily
J4G44_10920	COG4239	(ABC) transporter, permease
J4G44_10925	COG4174	ABC transporter (Permease)
J4G44_10930	COG4166	transmembrane transport
J4G44_10935	COG0741	lytic transglycosylase activity
J4G44_10935	COG1388	LysM domain
J4G44_10935	COG0741	lytic transglycosylase activity
J4G44_10935	COG1388	LysM domain
J4G44_10940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J4G44_10950	COG2816	NAD+ diphosphatase activity
J4G44_10980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4G44_10985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J4G44_10990	COG3077	Addiction module antitoxin, RelB DinJ family
J4G44_11000	COG0006	proline dipeptidase activity
J4G44_11005	COG3079	Belongs to the UPF0149 family
J4G44_11030	COG4680	protein conserved in bacteria
J4G44_11035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J4G44_11040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J4G44_11060	COG0789	Transcriptional regulator
J4G44_11075	COG5002	protein histidine kinase activity
J4G44_11080	COG4372	Transposase
J4G44_11100	COG0642	Histidine kinase
J4G44_11120	COG3706	GGDEF domain
J4G44_11135	COG0277	FAD linked oxidase domain protein
J4G44_11145	COG2186	Transcriptional regulator
J4G44_11165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J4G44_11175	COG2234	aminopeptidase activity
J4G44_11185	COG3384	dioxygenase
J4G44_11195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4G44_11200	COG2878	Part of a membrane complex involved in electron transport
J4G44_11205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J4G44_11235	COG0768	penicillin binding
J4G44_11240	COG0742	ribosomal rna small subunit methyltransferase
J4G44_11245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4G44_11270	COG1253	flavin adenine dinucleotide binding
J4G44_11290	COG3118	belongs to the thioredoxin family
J4G44_11295	COG2203	Gaf domain
J4G44_11295	COG2199	diguanylate cyclase activity
J4G44_11305	COG4681	YaeQ
J4G44_11310	COG0523	cobalamin synthesis protein
J4G44_11320	COG1607	acyl-coa hydrolase
J4G44_11330	COG1752	Esterase of the alpha-beta hydrolase superfamily
J4G44_11340	COG2826	transposase and inactivated derivatives, IS30 family
J4G44_11350	COG0786	glutamate:sodium symporter activity
J4G44_11360	COG2814	Major facilitator Superfamily
J4G44_11365	COG1289	transmembrane transporter activity
J4G44_11435	COG2832	Protein of unknown function (DUF454)
J4G44_11445	COG5510	response to toxic substance
J4G44_11450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4G44_11460	COG2198	Histidine kinase
J4G44_11460	COG0643	Histidine kinase
J4G44_11460	COG2198	Histidine kinase
J4G44_11460	COG0643	Histidine kinase
J4G44_11465	COG0840	transmembrane signaling receptor activity
J4G44_11490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J4G44_11535	COG0489	protein tyrosine kinase activity
J4G44_11540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4G44_11540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4G44_11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J4G44_11575	COG2081	HI0933 family
J4G44_11590	COG0668	transmembrane transport
J4G44_11615	COG0583	DNA-binding transcription factor activity
J4G44_11620	COG1278	Cold shock
J4G44_11625	COG1278	Cold shock
J4G44_11640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4G44_11645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4G44_11650	COG0713	ATP synthesis coupled electron transport
J4G44_11660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4G44_11675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J4G44_11685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4G44_11685	COG0649	NAD binding
J4G44_11695	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4G44_11705	COG0142	geranyltranstransferase activity
J4G44_11710	COG2828	Protein conserved in bacteria
J4G44_11715	COG1113	amino acid transport
J4G44_11720	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J4G44_11725	COG1840	ABC-type Fe3 transport system, periplasmic component
J4G44_11755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J4G44_11765	COG1530	ribonuclease E activity
J4G44_11770	COG0424	maF-like protein
J4G44_11775	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J4G44_11780	COG1792	Involved in formation and maintenance of cell shape
J4G44_11785	COG1077	Cell shape determining protein MreB Mrl
J4G44_11790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J4G44_11800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J4G44_11820	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J4G44_11835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4G44_11860	COG1136	(ABC) transporter
J4G44_11860	COG0577	efflux transmembrane transporter activity
J4G44_11870	COG0730	response to heat
J4G44_11885	COG0300	oxidoreductase activity
J4G44_11895	COG1022	Amp-dependent synthetase and ligase
J4G44_11905	COG2050	protein possibly involved in aromatic compounds catabolism
J4G44_11920	COG1090	epimerase
J4G44_11930	COG0420	3'-5' exonuclease activity
J4G44_11960	COG0735	belongs to the Fur family
J4G44_11965	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J4G44_11970	COG2914	Belongs to the UPF0125 (RnfH) family
J4G44_11990	COG0121	glutamine amidotransferase
J4G44_12000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4G44_12005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4G44_12010	COG0756	dUTP diphosphatase activity
J4G44_12015	COG0210	DNA helicase
J4G44_12020	COG2885	chlorophyll binding
J4G44_12025	COG0204	Acyl-transferase
J4G44_12040	COG2894	cell division
J4G44_12055	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J4G44_12055	COG1674	ftsk spoiiie
J4G44_12060	COG0492	ferredoxin-NADP+ reductase activity
J4G44_12065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J4G44_12075	COG0456	acetyltransferase
J4G44_12115	COG1981	membrane
J4G44_12130	COG0352	thiamine-phosphate diphosphorylase activity
J4G44_12130	COG0351	phosphomethylpyrimidine kinase
J4G44_12140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4G44_12160	COG2132	Multicopper oxidase
J4G44_12170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4G44_12185	COG4269	membrane
J4G44_12205	COG1968	undecaprenyl-diphosphatase activity
J4G44_12210	COG1214	PFAM Peptidase M22, glycoprotease
J4G44_12220	COG0494	nUDIX hydrolase
J4G44_12270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4G44_12275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J4G44_12340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J4G44_12380	COG0037	tRNA processing
J4G44_12390	COG0248	Ppx GppA phosphatase
J4G44_12415	COG0072	phenylalanine-tRNA ligase activity
J4G44_12420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J4G44_12445	COG1238	metal cluster binding
J4G44_12455	COG0625	glutathione transferase activity
J4G44_12460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J4G44_12490	COG0318	PFAM AMP-dependent synthetase and ligase
J4G44_12495	COG3028	Belongs to the UPF0307 family
J4G44_12505	COG1660	Displays ATPase and GTPase activities
J4G44_12520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4G44_12590	COG3012	SEC-C Motif Domain Protein
J4G44_12650	COG1373	ATPase (AAA superfamily
J4G44_12665	COG2831	hemolysin activation secretion protein
J4G44_12670	COG3210	domain, Protein
J4G44_12705	COG0582	viral genome integration into host DNA
J4G44_12710	COG0789	Transcriptional regulator
J4G44_12720	COG1230	cation diffusion facilitator family transporter
J4G44_12755	COG1683	Conserved Protein
J4G44_12790	COG4974	Belongs to the 'phage' integrase family
J4G44_12855	COG0551	DNA topoisomerase type I activity
J4G44_12855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4G44_12865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4G44_12900	COG3173	Aminoglycoside phosphotransferase
J4G44_12925	COG0583	DNA-binding transcription factor activity
J4G44_12945	COG2801	Transposase and inactivated derivatives
J4G44_12955	COG3657	addiction module killer protein
J4G44_12960	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4G44_12965	COG0659	secondary active sulfate transmembrane transporter activity
J4G44_12975	COG3657	addiction module killer protein
J4G44_12980	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4G44_13000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J4G44_13010	COG5002	protein histidine kinase activity
J4G44_13015	COG0745	RESPONSE REGULATOR receiver
J4G44_13020	COG2801	Transposase and inactivated derivatives
J4G44_13055	COG3657	addiction module killer protein
J4G44_13060	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4G44_13065	COG2801	Transposase and inactivated derivatives
J4G44_13140	COG1570	exodeoxyribonuclease VII activity
J4G44_13150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4G44_13185	COG2801	Transposase and inactivated derivatives
J4G44_13210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J4G44_13230	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J4G44_13265	COG3173	Aminoglycoside phosphotransferase
J4G44_13270	COG0488	(ABC) transporter
J4G44_13285	COG0488	(ABC) transporter
J4G44_13310	COG0488	(ABC) transporter
J4G44_13335	COG1401	restriction endodeoxyribonuclease activity
J4G44_13380	COG3077	Addiction module antitoxin, RelB DinJ family
J4G44_13385	COG0488	(ABC) transporter
J4G44_13435	COG2132	Multicopper oxidase
J4G44_13455	COG4221	oxidoreductase activity
J4G44_13460	COG0488	(ABC) transporter
J4G44_13485	COG2801	Transposase and inactivated derivatives
J4G44_13520	COG2801	Transposase and inactivated derivatives
J4G44_13535	COG3077	Addiction module antitoxin, RelB DinJ family