locus-tag	class	description
LZG54_00010	COG0592	DNA-directed DNA polymerase activity
LZG54_00020	COG0187	DNA topoisomerase II activity
LZG54_00035	COG0488	(ABC) transporter
LZG54_00050	COG0316	Belongs to the HesB IscA family
LZG54_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LZG54_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LZG54_00095	COG1047	Peptidyl-prolyl cis-trans
LZG54_00105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LZG54_00110	COG0196	riboflavin kinase activity
LZG54_00120	COG1309	transcriptional regulator
LZG54_00125	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LZG54_00125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZG54_00150	COG1028	Short-chain dehydrogenase reductase Sdr
LZG54_00155	COG0546	phosphoglycolate phosphatase activity
LZG54_00160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZG54_00175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LZG54_00190	COG3023	N-Acetylmuramoyl-L-alanine amidase
LZG54_00210	COG1064	alcohol dehydrogenase
LZG54_00215	COG2818	Glycosylase
LZG54_00230	COG1194	a g-specific adenine glycosylase
LZG54_00245	COG5487	UPF0391 membrane protein
LZG54_00250	COG2983	Belongs to the UPF0260 family
LZG54_00255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZG54_00265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LZG54_00275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZG54_00285	COG1335	isochorismatase
LZG54_00300	COG0560	Phosphoserine phosphatase
LZG54_00300	COG3830	Belongs to the UPF0237 family
LZG54_00360	COG0534	Mate efflux family protein
LZG54_00365	COG0436	Aminotransferase
LZG54_00370	COG2733	membrane
LZG54_00385	COG2918	glutathione biosynthetic process
LZG54_00400	COG3150	esterase
LZG54_00410	COG0471	metal ion transport
LZG54_00465	COG1393	Belongs to the ArsC family
LZG54_00470	COG0708	Exodeoxyribonuclease III
LZG54_00475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LZG54_00485	COG0189	ligase activity
LZG54_00505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZG54_00515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZG54_00520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZG54_00545	COG2119	membrane
LZG54_00550	COG0426	domain, Protein
LZG54_00550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LZG54_00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZG54_00575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZG54_00600	COG1902	pentaerythritol trinitrate reductase activity
LZG54_00605	COG1519	Transferase
LZG54_00615	COG0668	transmembrane transport
LZG54_00620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LZG54_00665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZG54_00675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZG54_00680	COG2808	Putative FMN-binding domain
LZG54_00690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZG54_00695	COG0235	Class ii aldolase
LZG54_00735	COG4372	Transposase
LZG54_00760	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_00785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZG54_00795	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LZG54_00800	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZG54_00805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZG54_00835	COG3177	Filamentation induced by cAMP protein fic
LZG54_00850	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_00855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LZG54_00895	COG3293	Transposase
LZG54_00940	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_00970	COG0582	viral genome integration into host DNA
LZG54_00980	COG3158	transport of potassium into the cell
LZG54_01025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LZG54_01040	COG0697	spore germination
LZG54_01060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LZG54_01095	COG0427	acetyl-CoA hydrolase
LZG54_01110	COG2183	response to ionizing radiation
LZG54_01120	COG4221	oxidoreductase activity
LZG54_01130	COG0488	(ABC) transporter
LZG54_01150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZG54_01165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LZG54_01170	COG0275	rRNA processing
LZG54_01185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LZG54_01190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZG54_01195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LZG54_01200	COG2226	methyltransferase
LZG54_01255	COG0493	'glutamate synthase
LZG54_01260	COG1704	LemA family
LZG54_01265	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LZG54_01295	COG0463	Glycosyl transferase, family 2
LZG54_01315	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LZG54_01320	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_01340	COG3307	-O-antigen
LZG54_01350	COG3609	addiction module antidote protein, CC2985 family
LZG54_01370	COG2906	2 iron, 2 sulfur cluster binding
LZG54_01380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZG54_01385	COG1758	RNA polymerase activity
LZG54_01390	COG0194	GDP metabolic process
LZG54_01435	COG0228	four-way junction DNA binding
LZG54_01440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LZG54_01450	COG0335	large ribosomal subunit rRNA binding
LZG54_01465	COG5380	lipid catabolic process
LZG54_01470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LZG54_01485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZG54_01490	COG0277	FAD linked oxidase domain protein
LZG54_01510	COG2814	Major facilitator Superfamily
LZG54_01515	COG2032	superoxide dismutase activity
LZG54_01520	COG0628	permease
LZG54_01525	COG1192	Involved in chromosome partitioning
LZG54_01535	COG2226	methyltransferase
LZG54_01550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LZG54_01555	COG0254	rRNA binding
LZG54_01560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LZG54_01565	COG0534	Mate efflux family protein
LZG54_01575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZG54_01580	COG1960	acyl-CoA dehydrogenase activity
LZG54_01595	COG0408	coproporphyrinogen oxidase activity
LZG54_01600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZG54_01620	COG0513	Belongs to the DEAD box helicase family
LZG54_01625	COG1127	ABC transporter
LZG54_01630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZG54_01635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZG54_01640	COG2854	intermembrane phospholipid transfer
LZG54_01650	COG0598	Magnesium transport protein CorA
LZG54_01665	COG1040	competence protein
LZG54_01670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZG54_01680	COG2937	Belongs to the GPAT DAPAT family
LZG54_01685	COG1946	Acyl-CoA thioesterase
LZG54_01690	COG1301	dicarboxylic acid transport
LZG54_01705	COG1959	2 iron, 2 sulfur cluster binding
LZG54_01715	COG0433	COG0433 Predicted ATPase
LZG54_01735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LZG54_01740	COG0088	Forms part of the polypeptide exit tunnel
LZG54_01755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LZG54_01795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LZG54_01805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LZG54_01810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LZG54_01820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LZG54_01845	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LZG54_01855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LZG54_01865	COG0203	ribosomal protein L17
LZG54_01870	COG2072	flavoprotein involved in K transport
LZG54_01875	COG1960	acyl-CoA dehydrogenase activity
LZG54_01880	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LZG54_01915	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LZG54_01920	COG0339	signal peptide processing
LZG54_01925	COG0557	exoribonuclease II activity
LZG54_01955	COG0179	Fumarylacetoacetate (FAA) hydrolase
LZG54_01980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LZG54_02020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LZG54_02035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZG54_02035	COG2813	Specifically methylates the guanine in position
LZG54_02040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZG54_02045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LZG54_02055	COG3128	pkhd-type hydroxylase
LZG54_02065	COG4771	TonB-dependent receptor
LZG54_02075	COG0740	serine-type endopeptidase activity
LZG54_02090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LZG54_02090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LZG54_02100	COG0280	phosphate acetyltransferase
LZG54_02100	COG0857	belongs to the CobB CobQ family
LZG54_02105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LZG54_02120	COG2267	carboxylic ester hydrolase activity
LZG54_02150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LZG54_02165	COG0084	hydrolase, TatD family'
LZG54_02170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZG54_02175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZG54_02185	COG2814	Major facilitator Superfamily
LZG54_02215	COG3622	Belongs to the hyi family
LZG54_02220	COG2084	Dehydrogenase
LZG54_02225	COG1024	Enoyl-CoA hydratase
LZG54_02230	COG0784	Response regulator, receiver
LZG54_02230	COG2205	protein histidine kinase activity
LZG54_02230	COG5002	protein histidine kinase activity
LZG54_02250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZG54_02270	COG1862	Preprotein translocase
LZG54_02280	COG2203	Gaf domain
LZG54_02280	COG3706	GGDEF domain
LZG54_02280	COG4251	negative regulation of phosphorylation
LZG54_02280	COG5001	Diguanylate cyclase
LZG54_02285	COG1704	LemA family
LZG54_02295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LZG54_02315	COG2205	protein histidine kinase activity
LZG54_02315	COG0784	Response regulator, receiver
LZG54_02315	COG5002	protein histidine kinase activity
LZG54_02320	COG1538	Outer membrane efflux protein
LZG54_02325	COG0577	efflux transmembrane transporter activity
LZG54_02325	COG1136	(ABC) transporter
LZG54_02330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZG54_02335	COG2703	oxygen carrier activity
LZG54_02360	COG0028	Belongs to the TPP enzyme family
LZG54_02390	COG0726	polysaccharide deacetylase
LZG54_02395	COG0463	Glycosyl transferase, family 2
LZG54_02400	COG0438	transferase activity, transferring glycosyl groups
LZG54_02410	COG0438	transferase activity, transferring glycosyl groups
LZG54_02425	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LZG54_02440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZG54_02460	COG1960	acyl-CoA dehydrogenase activity
LZG54_02465	COG1960	acyl-CoA dehydrogenase activity
LZG54_02475	COG2205	protein histidine kinase activity
LZG54_02480	COG0745	RESPONSE REGULATOR receiver
LZG54_02485	COG2315	Protein conserved in bacteria
LZG54_02490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LZG54_02505	COG2096	Adenosyltransferase
LZG54_02510	COG4206	TonB-dependent receptor
LZG54_02540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LZG54_02585	COG2975	iron-sulfur cluster assembly
LZG54_02605	COG1426	Protein conserved in bacteria
LZG54_02625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZG54_02640	COG3956	TIGRFAM MazG family protein
LZG54_02645	COG1555	photosystem II stabilization
LZG54_02645	COG1596	polysaccharide export
LZG54_02650	COG0617	tRNA 3'-terminal CCA addition
LZG54_02655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZG54_02670	COG1660	Displays ATPase and GTPase activities
LZG54_02680	COG3028	Belongs to the UPF0307 family
LZG54_02685	COG0318	PFAM AMP-dependent synthetase and ligase
LZG54_02700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZG54_02715	COG0625	glutathione transferase activity
LZG54_02725	COG1238	metal cluster binding
LZG54_02775	COG2314	TM2 domain
LZG54_02785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LZG54_02790	COG0072	phenylalanine-tRNA ligase activity
LZG54_02815	COG0248	Ppx GppA phosphatase
LZG54_02825	COG0037	tRNA processing
LZG54_02875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZG54_02955	COG1607	acyl-coa hydrolase
LZG54_02985	COG2350	Protein conserved in bacteria
LZG54_02995	COG0613	PHP domain protein
LZG54_03000	COG3781	membrane
LZG54_03005	COG2003	Belongs to the UPF0758 family
LZG54_03010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZG54_03020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LZG54_03030	COG1162	GTPase activity
LZG54_03035	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LZG54_03055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZG54_03060	COG0285	dihydrofolate synthase activity
LZG54_03075	COG0450	alkyl hydroperoxide reductase
LZG54_03090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LZG54_03095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LZG54_03170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LZG54_03175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LZG54_03225	COG0494	nUDIX hydrolase
LZG54_03235	COG1214	PFAM Peptidase M22, glycoprotease
LZG54_03240	COG1968	undecaprenyl-diphosphatase activity
LZG54_03260	COG4269	membrane
LZG54_03275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LZG54_03285	COG2132	Multicopper oxidase
LZG54_03300	COG2076	Multidrug Resistance protein
LZG54_03305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZG54_03315	COG0352	thiamine-phosphate diphosphorylase activity
LZG54_03315	COG0351	phosphomethylpyrimidine kinase
LZG54_03330	COG1981	membrane
LZG54_03370	COG0456	acetyltransferase
LZG54_03380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LZG54_03385	COG0492	ferredoxin-NADP+ reductase activity
LZG54_03390	COG1674	ftsk spoiiie
LZG54_03390	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZG54_03405	COG2894	cell division
LZG54_03420	COG0204	Acyl-transferase
LZG54_03425	COG2885	chlorophyll binding
LZG54_03430	COG0210	DNA helicase
LZG54_03435	COG0756	dUTP diphosphatase activity
LZG54_03440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZG54_03445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZG54_03455	COG0121	glutamine amidotransferase
LZG54_03470	COG2914	Belongs to the UPF0125 (RnfH) family
LZG54_03475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZG54_03480	COG0735	belongs to the Fur family
LZG54_03510	COG0420	3'-5' exonuclease activity
LZG54_03520	COG1090	epimerase
LZG54_03525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZG54_03535	COG2050	protein possibly involved in aromatic compounds catabolism
LZG54_03540	COG4774	siderophore transport
LZG54_03555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LZG54_03570	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LZG54_03595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LZG54_03605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LZG54_03610	COG1077	Cell shape determining protein MreB Mrl
LZG54_03615	COG1792	Involved in formation and maintenance of cell shape
LZG54_03620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZG54_03625	COG0424	maF-like protein
LZG54_03630	COG1530	ribonuclease E activity
LZG54_03640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LZG54_03650	COG0560	Phosphoserine phosphatase
LZG54_03670	COG1840	ABC-type Fe3 transport system, periplasmic component
LZG54_03675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LZG54_03680	COG1113	amino acid transport
LZG54_03685	COG2828	Protein conserved in bacteria
LZG54_03690	COG0142	geranyltranstransferase activity
LZG54_03700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZG54_03710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZG54_03710	COG0649	NAD binding
LZG54_03720	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZG54_03735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZG54_03745	COG0713	ATP synthesis coupled electron transport
LZG54_03750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LZG54_03755	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZG54_03765	COG4372	Transposase
LZG54_03785	COG1278	Cold shock
LZG54_03790	COG1278	Cold shock
LZG54_03795	COG0583	DNA-binding transcription factor activity
LZG54_03815	COG0668	transmembrane transport
LZG54_03825	COG2081	HI0933 family
LZG54_03830	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LZG54_03845	COG4716	Myosin-crossreactive antigen
LZG54_03855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZG54_03865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZG54_03865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZG54_03870	COG0489	protein tyrosine kinase activity
LZG54_03950	COG0840	transmembrane signaling receptor activity
LZG54_03955	COG2198	Histidine kinase
LZG54_03955	COG0643	Histidine kinase
LZG54_03965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZG54_03970	COG5510	response to toxic substance
LZG54_03980	COG2832	Protein of unknown function (DUF454)
LZG54_03985	COG1376	ErfK ybiS ycfS ynhG family protein
LZG54_04050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZG54_04060	COG1289	transmembrane transporter activity
LZG54_04065	COG2814	Major facilitator Superfamily
LZG54_04075	COG0786	glutamate:sodium symporter activity
LZG54_04085	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZG54_04095	COG1607	acyl-coa hydrolase
LZG54_04105	COG0523	cobalamin synthesis protein
LZG54_04110	COG4681	YaeQ
LZG54_04120	COG2199	diguanylate cyclase activity
LZG54_04120	COG2203	Gaf domain
LZG54_04140	COG1253	flavin adenine dinucleotide binding
LZG54_04165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LZG54_04170	COG0742	ribosomal rna small subunit methyltransferase
LZG54_04175	COG0768	penicillin binding
LZG54_04200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZG54_04205	COG2878	Part of a membrane complex involved in electron transport
LZG54_04210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LZG54_04215	COG3384	dioxygenase
LZG54_04225	COG2234	aminopeptidase activity
LZG54_04235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZG54_04245	COG2186	Transcriptional regulator
LZG54_04255	COG0277	FAD linked oxidase domain protein
LZG54_04285	COG0642	Histidine kinase
LZG54_04290	COG0745	RESPONSE REGULATOR receiver
LZG54_04295	COG2194	sulfuric ester hydrolase activity
LZG54_04310	COG0789	Transcriptional regulator
LZG54_04330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LZG54_04335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LZG54_04340	COG4680	protein conserved in bacteria
LZG54_04365	COG3079	Belongs to the UPF0149 family
LZG54_04370	COG0006	proline dipeptidase activity
LZG54_04375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZG54_04380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZG54_04410	COG2816	NAD+ diphosphatase activity
LZG54_04420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZG54_04425	COG0741	lytic transglycosylase activity
LZG54_04425	COG1388	LysM domain
LZG54_04425	COG0741	lytic transglycosylase activity
LZG54_04425	COG1388	LysM domain
LZG54_04430	COG4166	transmembrane transport
LZG54_04435	COG4174	ABC transporter (Permease)
LZG54_04440	COG4239	(ABC) transporter, permease
LZG54_04445	COG4172	Belongs to the ABC transporter superfamily
LZG54_04475	COG0833	amino acid
LZG54_04490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZG54_04495	COG0418	dihydroorotase activity
LZG54_04500	COG5001	Diguanylate cyclase
LZG54_04500	COG2203	Gaf domain
LZG54_04500	COG3706	GGDEF domain
LZG54_04500	COG4251	negative regulation of phosphorylation
LZG54_04510	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZG54_04510	COG1902	pentaerythritol trinitrate reductase activity
LZG54_04525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZG54_04540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LZG54_04540	COG0047	phosphoribosylformylglycinamidine synthase activity
LZG54_04565	COG5001	Diguanylate cyclase
LZG54_04565	COG3300	MHYT domain
LZG54_04570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZG54_04575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZG54_04580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LZG54_04590	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LZG54_04610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZG54_04615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZG54_04640	COG0052	Belongs to the universal ribosomal protein uS2 family
LZG54_04665	COG2951	lytic endotransglycosylase activity
LZG54_04680	COG0842	Transport permease protein
LZG54_04685	COG1131	(ABC) transporter
LZG54_04695	COG0582	viral genome integration into host DNA
LZG54_04740	COG2184	nucleotidyltransferase activity
LZG54_04750	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LZG54_04760	COG4804	nuclease activity
LZG54_04795	COG0640	Transcriptional regulator
LZG54_04805	COG0798	PFAM Bile acid sodium symporter
LZG54_04810	COG0431	NADPH-dependent FMN reductase
LZG54_04820	COG3177	Filamentation induced by cAMP protein fic
LZG54_04860	COG3293	Transposase
LZG54_04900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZG54_04920	COG3634	alkyl hydroperoxide reductase activity
LZG54_04925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZG54_04930	COG0826	peptidase U32
LZG54_04940	COG0640	Transcriptional regulator
LZG54_04960	COG0431	NADPH-dependent FMN reductase
LZG54_04965	COG0789	Transcriptional regulator
LZG54_04990	COG1720	tRNA m6t6A37 methyltransferase activity
LZG54_05005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZG54_05020	COG0642	Histidine kinase
LZG54_05030	COG0352	thiamine-phosphate diphosphorylase activity
LZG54_05040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZG54_05045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LZG54_05050	COG3139	Protein of unknown function (DUF1315)
LZG54_05070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZG54_05075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LZG54_05090	COG0415	Belongs to the DNA photolyase family
LZG54_05095	COG1047	Peptidyl-prolyl cis-trans
LZG54_05100	COG1686	Belongs to the peptidase S11 family
LZG54_05125	COG0612	Peptidase, M16
LZG54_05160	COG0352	thiamine-phosphate diphosphorylase activity
LZG54_05190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LZG54_05190	COG1017	nitric oxide dioxygenase activity
LZG54_05250	COG1643	Atp-dependent helicase
LZG54_05270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LZG54_05270	COG0517	IMP dehydrogenase activity
LZG54_05275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZG54_05285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LZG54_05290	COG1137	ATPase activity
LZG54_05310	COG4122	O-methyltransferase activity
LZG54_05320	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZG54_05360	COG2011	ABC-type metal ion transport system permease component
LZG54_05365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LZG54_05370	COG1464	Belongs to the NlpA lipoprotein family
LZG54_05380	COG0138	bifunctional purine biosynthesis protein purh
LZG54_05385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LZG54_05430	COG0183	Belongs to the thiolase family
LZG54_05445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LZG54_05455	COG0305	Participates in initiation and elongation during chromosome replication
LZG54_05465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LZG54_05470	COG0360	Binds together with S18 to 16S ribosomal RNA
LZG54_05480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZG54_05485	COG1845	cytochrome c oxidase, subunit III
LZG54_05490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZG54_05495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZG54_05520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZG54_05535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LZG54_05540	COG2890	protein-(glutamine-N5) methyltransferase activity
LZG54_05545	COG3781	membrane
LZG54_05575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZG54_05585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZG54_05600	COG0477	Major facilitator Superfamily
LZG54_05605	COG0729	surface antigen
LZG54_05635	COG0308	aminopeptidase N
LZG54_05640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZG54_05650	COG0589	response to stress
LZG54_05655	COG0589	response to stress
LZG54_05675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LZG54_05690	COG0183	Belongs to the thiolase family
LZG54_05705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LZG54_05710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LZG54_05715	COG1454	alcohol dehydrogenase
LZG54_05720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZG54_05740	COG2197	response regulator
LZG54_05745	COG4585	Histidine kinase
LZG54_05750	COG2850	peptidyl-arginine hydroxylation
LZG54_05755	COG0424	maF-like protein
LZG54_05765	COG0126	phosphoglycerate kinase activity
LZG54_05800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZG54_05810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZG54_05840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LZG54_05845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LZG54_05850	COG2267	carboxylic ester hydrolase activity
LZG54_05860	COG1902	pentaerythritol trinitrate reductase activity
LZG54_05860	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZG54_05890	COG0148	phosphopyruvate hydratase activity
LZG54_05895	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LZG54_05905	COG0772	Belongs to the SEDS family
LZG54_05930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZG54_05935	COG0730	response to heat
LZG54_05940	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZG54_05980	COG4890	Cyd operon protein YbgT
LZG54_05985	COG1294	oxidase, subunit
LZG54_06005	COG1585	Membrane protein implicated in regulation of membrane protease activity
LZG54_06015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZG54_06035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LZG54_06040	COG0569	domain protein
LZG54_06045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LZG54_06050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LZG54_06070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LZG54_06075	COG0542	response to heat
LZG54_06105	COG0372	Belongs to the citrate synthase family
LZG54_06115	COG1058	Belongs to the CinA family
LZG54_06115	COG1546	Belongs to the CinA family
LZG54_06135	COG2814	Major facilitator Superfamily
LZG54_06145	COG2203	Gaf domain
LZG54_06145	COG2199	diguanylate cyclase activity
LZG54_06160	COG0668	transmembrane transport
LZG54_06165	COG3122	Protein conserved in bacteria
LZG54_06170	COG3619	membrane
LZG54_06190	COG2937	Belongs to the GPAT DAPAT family
LZG54_06195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZG54_06205	COG0183	Belongs to the thiolase family
LZG54_06210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZG54_06215	COG0183	Belongs to the thiolase family
LZG54_06220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LZG54_06225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LZG54_06230	COG3135	benzoate transporter
LZG54_06235	COG1028	Short-chain dehydrogenase reductase Sdr
LZG54_06240	COG0543	2 iron, 2 sulfur cluster binding
LZG54_06240	COG0633	Ferredoxin
LZG54_06245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LZG54_06250	COG4638	Rieske (2fe-2S)
LZG54_06260	COG4829	muconolactone delta-isomerase
LZG54_06265	COG4948	Mandelate Racemase Muconate Lactonizing
LZG54_06270	COG0583	DNA-binding transcription factor activity
LZG54_06275	COG2814	Major facilitator Superfamily
LZG54_06285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZG54_06330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LZG54_06335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LZG54_06365	COG1960	acyl-CoA dehydrogenase activity
LZG54_06395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZG54_06415	COG2814	Major facilitator Superfamily
LZG54_06425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZG54_06450	COG2390	Transcriptional regulator
LZG54_06450	COG4584	PFAM Integrase catalytic
LZG54_06455	COG1484	DNA-dependent DNA replication
LZG54_06475	COG1132	(ABC) transporter
LZG54_06480	COG4628	conserved protein (DUF2132)
LZG54_06580	COG1201	RNA secondary structure unwinding
LZG54_06620	COG4372	Transposase
LZG54_06650	COG4372	Transposase
LZG54_06665	COG0604	alcohol dehydrogenase
LZG54_06670	COG1309	transcriptional regulator
LZG54_06675	COG4628	conserved protein (DUF2132)
LZG54_06690	COG1335	isochorismatase
LZG54_06695	COG1280	lysine exporter protein (LysE YggA)
LZG54_06710	COG1063	alcohol dehydrogenase
LZG54_06720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZG54_06725	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZG54_06730	COG0022	dehydrogenase e1 component
LZG54_06735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LZG54_06740	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZG54_06760	COG0515	serine threonine protein kinase
LZG54_06765	COG2116	formate transmembrane transporter activity
LZG54_06770	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LZG54_06790	COG2223	nitrite transmembrane transporter activity
LZG54_06795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LZG54_06800	COG4149	molybdate abc transporter
LZG54_06805	COG0725	ABC transporter, periplasmic molybdate-binding protein
LZG54_06810	COG0303	'Molybdopterin
LZG54_06815	COG0315	cyclic pyranopterin monophosphate synthase activity
LZG54_06815	COG0521	Mo-molybdopterin cofactor biosynthetic process
LZG54_06820	COG0314	molybdopterin synthase activity
LZG54_06830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LZG54_06840	COG0243	molybdopterin cofactor binding
LZG54_06845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZG54_06850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZG54_06860	COG1116	anion transmembrane transporter activity
LZG54_06860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LZG54_06895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LZG54_06900	COG1944	ATP diphosphatase activity
LZG54_06910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LZG54_06915	COG0511	ligase activity, forming carbon-carbon bonds
LZG54_06925	COG0596	Alpha beta hydrolase
LZG54_06945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LZG54_06950	COG1283	sodium-dependent phosphate transmembrane transporter activity
LZG54_07000	COG0552	protein localization to endoplasmic reticulum
LZG54_07005	COG0612	Peptidase, M16
LZG54_07035	COG0517	IMP dehydrogenase activity
LZG54_07040	COG0133	tryptophan synthase activity
LZG54_07050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZG54_07070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LZG54_07125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZG54_07155	COG0822	iron-sulfur transferase activity
LZG54_07160	COG0316	Belongs to the HesB IscA family
LZG54_07190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZG54_07205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZG54_07210	COG0702	epimerase
LZG54_07215	COG0268	Binds directly to 16S ribosomal RNA
LZG54_07240	COG1011	Hydrolase
LZG54_07245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LZG54_07255	COG2137	regulation of response to DNA damage stimulus
LZG54_07270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZG54_07280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZG54_07290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZG54_07305	COG0575	Belongs to the CDS family
LZG54_07310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZG54_07330	COG3852	Histidine kinase
LZG54_07345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZG54_07350	COG0583	DNA-binding transcription factor activity
LZG54_07355	COG0024	Methionine aminopeptidase
LZG54_07360	COG1114	Component of the transport system for branched-chain amino acids
LZG54_07380	COG1253	flavin adenine dinucleotide binding
LZG54_07395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LZG54_07400	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZG54_07415	COG2431	L-lysine efflux transmembrane transporter activity
LZG54_07460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LZG54_07480	COG2165	general secretion pathway protein
LZG54_07495	COG0084	hydrolase, TatD family'
LZG54_07515	COG1663	tetraacyldisaccharide 4'-kinase activity
LZG54_07520	COG1132	(ABC) transporter
LZG54_07530	COG0811	peptide transport
LZG54_07535	COG1475	DNA binding
LZG54_07540	COG1192	Involved in chromosome partitioning
LZG54_07550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZG54_07565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZG54_07600	COG4372	Transposase
LZG54_07610	COG1923	regulation of RNA biosynthetic process
LZG54_07620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LZG54_07625	COG0802	atpase or kinase
LZG54_07650	COG2707	UPF0756 membrane protein
LZG54_07655	COG0583	DNA-binding transcription factor activity
LZG54_07665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZG54_07670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZG54_07680	COG1454	alcohol dehydrogenase
LZG54_07700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZG54_07700	COG0519	Catalyzes the synthesis of GMP from XMP
LZG54_07705	COG2353	YceI-like domain
LZG54_07715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZG54_07720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LZG54_07760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZG54_07760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZG54_07775	COG3293	Transposase
LZG54_07795	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LZG54_07835	COG1309	transcriptional regulator
LZG54_07855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LZG54_07890	COG4221	oxidoreductase activity
LZG54_07910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZG54_07915	COG1309	transcriptional regulator
LZG54_07920	COG1012	belongs to the aldehyde dehydrogenase family
LZG54_07930	COG0579	oxidoreductase
LZG54_07955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZG54_07990	COG0642	Histidine kinase
LZG54_08005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZG54_08045	COG2816	NAD+ diphosphatase activity
LZG54_08050	COG3046	protein related to deoxyribodipyrimidine photolyase
LZG54_08065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZG54_08075	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_08085	COG3706	GGDEF domain
LZG54_08090	COG0582	viral genome integration into host DNA
LZG54_08095	COG0582	viral genome integration into host DNA
LZG54_08120	COG1487	ribonuclease activity
LZG54_08140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZG54_08165	COG4584	PFAM Integrase catalytic
LZG54_08165	COG2390	Transcriptional regulator
LZG54_08170	COG1484	DNA-dependent DNA replication
LZG54_08185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LZG54_08310	COG0443	Heat shock 70 kDa protein
LZG54_08315	COG1074	ATP-dependent DNA helicase activity
LZG54_08325	COG0582	viral genome integration into host DNA
LZG54_08365	COG1401	restriction endodeoxyribonuclease activity
LZG54_08400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZG54_08405	COG1028	Short-chain dehydrogenase reductase Sdr
LZG54_08445	COG2986	histidine ammonia-lyase
LZG54_08460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZG54_08470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZG54_08475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZG54_08525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZG54_08550	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LZG54_08680	COG0012	GTP binding
LZG54_08690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LZG54_08700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LZG54_08705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LZG54_08715	COG0386	Belongs to the glutathione peroxidase family
LZG54_08725	COG0436	Aminotransferase
LZG54_08755	COG0515	serine threonine protein kinase
LZG54_08755	COG2815	serine threonine protein kinase
LZG54_08785	COG1610	YqeY-like protein
LZG54_08825	COG1286	toxin biosynthetic process
LZG54_08830	COG0167	dihydroorotate dehydrogenase activity
LZG54_08855	COG0778	Nitroreductase
LZG54_08865	COG0513	Belongs to the DEAD box helicase family
LZG54_08870	COG1278	Cold shock
LZG54_08885	COG2363	Small membrane protein
LZG54_08905	COG0659	secondary active sulfate transmembrane transporter activity
LZG54_08910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LZG54_08935	COG2885	chlorophyll binding
LZG54_08935	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LZG54_08945	COG0540	Belongs to the ATCase OTCase family
LZG54_08970	COG1765	OsmC-like protein
LZG54_08980	COG0667	Aldo Keto reductase
LZG54_08995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LZG54_09010	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZG54_09015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZG54_09020	COG0527	aspartate kinase activity
LZG54_09030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LZG54_09040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LZG54_09045	COG2252	PERMEase
LZG54_09120	COG0582	viral genome integration into host DNA
LZG54_09140	COG0714	Associated with various cellular activities
LZG54_09145	COG2879	small protein
LZG54_09150	COG1966	Carbon starvation protein
LZG54_09155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZG54_09160	COG1509	lysine 2,3-aminomutase activity
LZG54_09195	COG1067	ATP-dependent peptidase activity
LZG54_09200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZG54_09205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZG54_09235	COG1686	Belongs to the peptidase S11 family
LZG54_09240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZG54_09255	COG2915	High frequency lysogenization protein hflD homolog
LZG54_09275	COG0616	signal peptide processing
LZG54_09290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LZG54_09300	COG0573	inorganic phosphate transmembrane transporter activity
LZG54_09310	COG0076	glutamate decarboxylase activity
LZG54_09315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZG54_09325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LZG54_09340	COG1733	regulation of RNA biosynthetic process
LZG54_09360	COG0556	nucleotide-excision repair
LZG54_09375	COG0436	Aminotransferase
LZG54_09400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LZG54_09415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LZG54_09420	COG0571	ribonuclease III activity
LZG54_09445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZG54_09455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZG54_09470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZG54_09480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LZG54_09495	COG4208	sulfate ABC transporter
LZG54_09500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LZG54_09505	COG0583	DNA-binding transcription factor activity
LZG54_09515	COG4625	pathogenesis
LZG54_09530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LZG54_09540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZG54_09545	COG1056	cytidyltransferase-related domain
LZG54_09545	COG1051	belongs to the nudix hydrolase family
LZG54_09550	COG1024	Enoyl-CoA hydratase
LZG54_09575	COG2255	four-way junction helicase activity
LZG54_09585	COG0824	Thioesterase
LZG54_09605	COG0823	Involved in the tonB-independent uptake of proteins
LZG54_09625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZG54_09655	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LZG54_09660	COG0628	permease
LZG54_09665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LZG54_09670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZG54_09690	COG0658	competence protein
LZG54_09690	COG2333	competence protein COMEC
LZG54_09700	COG1136	(ABC) transporter
LZG54_09705	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZG54_09730	COG1671	Belongs to the UPF0178 family
LZG54_09775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZG54_09790	COG0019	diaminopimelate decarboxylase activity
LZG54_09800	COG1113	amino acid transport
LZG54_09805	COG1115	amino acid carrier protein
LZG54_09820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZG54_09825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LZG54_09830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZG54_09865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LZG54_09875	COG0174	glutamine synthetase
LZG54_09880	COG0512	Glutamine amidotransferase of anthranilate synthase
LZG54_09885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZG54_09900	COG0302	gtp cyclohydrolase
LZG54_09905	COG3706	GGDEF domain
LZG54_09920	COG3739	integral membrane protein
LZG54_09935	COG1741	Belongs to the pirin family
LZG54_09940	COG2072	flavoprotein involved in K transport
LZG54_09985	COG0175	sulfate reduction
LZG54_10005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LZG54_10010	COG1773	rubredoxin
LZG54_10015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZG54_10025	COG0583	DNA-binding transcription factor activity
LZG54_10040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZG54_10045	COG0705	Rhomboid family
LZG54_10045	COG0457	Tetratricopeptide repeat
LZG54_10050	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LZG54_10055	COG4181	ATPase activity
LZG54_10105	COG0306	phosphate transporter
LZG54_10125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZG54_10145	COG1196	nuclear chromosome segregation
LZG54_10145	COG0741	lytic transglycosylase activity
LZG54_10145	COG0739	heme binding
LZG54_10150	COG0501	Belongs to the peptidase M48B family
LZG54_10160	COG2239	Acts as a magnesium transporter
LZG54_10185	COG0582	viral genome integration into host DNA
LZG54_10355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LZG54_10370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZG54_10410	COG0459	protein refolding
LZG54_10425	COG1597	lipid kinase activity
LZG54_10445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZG54_10485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZG54_10490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZG54_10515	COG0505	Belongs to the CarA family
LZG54_10540	COG0589	response to stress
LZG54_10545	COG3695	enzyme binding
LZG54_10550	COG2321	neutral zinc metallopeptidase
LZG54_10555	COG2354	Protein conserved in bacteria
LZG54_10565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZG54_10575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZG54_10590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZG54_10595	COG1053	succinate dehydrogenase
LZG54_10600	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZG54_10620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZG54_10620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZG54_10640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZG54_10665	COG0564	pseudouridine synthase activity
LZG54_10675	COG0358	DNA primase activity
LZG54_10680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LZG54_10690	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LZG54_10720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZG54_10745	COG1054	Belongs to the UPF0176 family
LZG54_10755	COG0586	Pfam SNARE associated Golgi protein
LZG54_10790	COG0321	lipoyl(octanoyl) transferase activity
LZG54_10805	COG0531	amino acid
LZG54_10815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZG54_10820	COG1648	precorrin-2 dehydrogenase activity
LZG54_10820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LZG54_10825	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LZG54_10835	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LZG54_10860	COG0671	phosphoesterase, PA-phosphatase related
LZG54_10865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZG54_10875	COG1538	Outer membrane efflux protein
LZG54_10880	COG0393	Putative heavy-metal-binding
LZG54_10885	COG0393	Putative heavy-metal-binding
LZG54_10890	COG1028	Short-chain dehydrogenase reductase Sdr
LZG54_10900	COG0525	valine-tRNA ligase activity
LZG54_10915	COG2323	membrane
LZG54_10930	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZG54_10945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZG54_10950	COG2205	protein histidine kinase activity
LZG54_10955	COG0745	RESPONSE REGULATOR receiver
LZG54_10965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZG54_10975	COG1652	LysM domain
LZG54_10985	COG1028	Short-chain dehydrogenase reductase Sdr
LZG54_11000	COG1399	metal-binding, possibly nucleic acid-binding protein
LZG54_11005	COG3101	peptidyl-lysine hydroxylation
LZG54_11010	COG0009	L-threonylcarbamoyladenylate synthase
LZG54_11015	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LZG54_11020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LZG54_11035	COG4106	trans-aconitate 2-methyltransferase activity
LZG54_11050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZG54_11050	COG2226	methyltransferase
LZG54_11050	COG0596	Alpha beta hydrolase
LZG54_11055	COG2193	ferroxidase activity
LZG54_11060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZG54_11065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LZG54_11070	COG3115	cell septum assembly
LZG54_11075	COG1196	nuclear chromosome segregation
LZG54_11085	COG0730	response to heat
LZG54_11100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZG54_11110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZG54_11125	COG3422	double-strand break repair
LZG54_11130	COG2824	Alkylphosphonate utilization operon protein PhnA
LZG54_11135	COG3189	MarR family transcriptional regulator
LZG54_11150	COG0564	pseudouridine synthase activity
LZG54_11175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LZG54_11180	COG0354	folic acid binding
LZG54_11195	COG1902	pentaerythritol trinitrate reductase activity
LZG54_11205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZG54_11210	COG1970	mechanosensitive ion channel activity
LZG54_11215	COG1217	gtp-binding protein TYPA
LZG54_11220	COG2233	PERMEase
LZG54_11230	COG0833	amino acid
LZG54_11245	COG0183	Belongs to the thiolase family
LZG54_11260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZG54_11265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LZG54_11270	COG2207	Transcriptional regulator
LZG54_11275	COG0183	Belongs to the thiolase family
LZG54_11280	COG1024	Enoyl-CoA hydratase
LZG54_11280	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZG54_11300	COG1272	protein, Hemolysin III
LZG54_11305	COG0477	Major facilitator Superfamily
LZG54_11310	COG1408	metallophosphoesterase
LZG54_11315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZG54_11325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZG54_11355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LZG54_11360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LZG54_11375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LZG54_11380	COG0625	glutathione transferase activity
LZG54_11385	COG2969	positive regulation of protein catabolic process
LZG54_11425	COG1183	phosphatidylcholine synthase activity
LZG54_11430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZG54_11460	COG3293	Transposase
LZG54_11480	COG0251	oxidation-reduction process
LZG54_11500	COG4372	Transposase
LZG54_11520	COG0741	lytic transglycosylase activity
LZG54_11520	COG0739	heme binding
LZG54_11520	COG1196	nuclear chromosome segregation
LZG54_11525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LZG54_11530	COG1702	phosphate starvation-inducible protein PhoH
LZG54_11535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LZG54_11575	COG1295	ribonuclease BN
LZG54_11600	COG0788	formyltetrahydrofolate deformylase activity
LZG54_11625	COG4651	solute:proton antiporter activity
LZG54_11625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZG54_11640	COG0724	RNA recognition motif
LZG54_11670	COG2900	Belongs to the SlyX family
LZG54_11675	COG0488	(ABC) transporter
LZG54_11680	COG1560	Kdo2-lipid A biosynthetic process
LZG54_11710	COG0252	asparaginase activity
LZG54_11715	COG0101	tRNA pseudouridine synthase activity
LZG54_11735	COG0473	3-isopropylmalate dehydrogenase activity
LZG54_11750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LZG54_11760	COG0583	DNA-binding transcription factor activity
LZG54_11790	COG0753	catalase activity
LZG54_11805	COG0583	DNA-binding transcription factor activity
LZG54_11815	COG0546	phosphoglycolate phosphatase activity
LZG54_11825	COG1530	ribonuclease E activity
LZG54_11830	COG0318	PFAM AMP-dependent synthetase and ligase
LZG54_11855	COG1983	PspC domain protein
LZG54_11860	COG0517	IMP dehydrogenase activity
LZG54_11860	COG0617	tRNA 3'-terminal CCA addition
LZG54_11860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LZG54_11870	COG0751	glycine-tRNA ligase activity
LZG54_11900	COG2226	methyltransferase
LZG54_11910	COG0493	'glutamate synthase
LZG54_11920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LZG54_11925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZG54_11940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LZG54_11950	COG0644	oxidoreductase
LZG54_11950	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZG54_11965	COG4535	Mg2 and Co2 transporter CorC
LZG54_11970	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LZG54_11985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZG54_11995	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZG54_12035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZG54_12040	COG1074	ATP-dependent DNA helicase activity
LZG54_12045	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZG54_12065	COG2226	methyltransferase
LZG54_12075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LZG54_12100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LZG54_12100	COG2111	Na H antiporter
LZG54_12105	COG1006	Multisubunit Na H antiporter MnhC subunit
LZG54_12110	COG0651	ATP synthesis coupled electron transport
LZG54_12115	COG1863	multisubunit Na H antiporter MnhE subunit
LZG54_12120	COG2212	antiporter activity
LZG54_12125	COG1320	monovalent cation:proton antiporter activity
LZG54_12130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LZG54_12135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LZG54_12140	COG0195	Participates in both transcription termination and antitermination
LZG54_12145	COG0779	Required for maturation of 30S ribosomal subunits
LZG54_12195	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZG54_12200	COG0237	dephospho-CoA kinase activity
LZG54_12210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZG54_12215	COG3123	guanosine phosphorylase activity
LZG54_12220	COG0497	DNA recombination
LZG54_12250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LZG54_12270	COG1132	(ABC) transporter
LZG54_12275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZG54_12285	COG0322	excinuclease ABC activity
LZG54_12305	COG1024	Enoyl-CoA hydratase
LZG54_12305	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZG54_12325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LZG54_12355	COG0326	Molecular chaperone. Has ATPase activity
LZG54_12365	COG3047	cAMP biosynthetic process
LZG54_12370	COG2056	Na+-H+ antiporter family
LZG54_12405	COG0085	RNA polymerase activity
LZG54_12420	COG0081	regulation of translation
LZG54_12505	COG0824	Thioesterase
LZG54_12525	COG0181	hydroxymethylbilane synthase activity
LZG54_12535	COG3275	phosphorelay sensor kinase activity
LZG54_12540	COG0165	Argininosuccinate lyase
LZG54_12555	COG1538	Outer membrane efflux protein
LZG54_12575	COG0494	nUDIX hydrolase
LZG54_12580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LZG54_12585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LZG54_12590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZG54_12600	COG0772	Belongs to the SEDS family
LZG54_12625	COG4974	Belongs to the 'phage' integrase family
LZG54_12630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZG54_12640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LZG54_12650	COG2197	response regulator
LZG54_12665	COG0793	Belongs to the peptidase S41A family
LZG54_12670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LZG54_12675	COG0795	lipopolysaccharide-transporting ATPase activity
LZG54_12680	COG0795	lipopolysaccharide-transporting ATPase activity
LZG54_12705	COG0586	Pfam SNARE associated Golgi protein
LZG54_12720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZG54_12720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZG54_12730	COG0004	ammonium transporteR
LZG54_12735	COG0347	Belongs to the P(II) protein family
LZG54_12745	COG0606	chelatase, subunit chli
LZG54_12760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZG54_12775	COG0318	PFAM AMP-dependent synthetase and ligase
LZG54_12790	COG0477	Major facilitator Superfamily
LZG54_12795	COG2860	membrane
LZG54_12805	COG1253	flavin adenine dinucleotide binding
LZG54_12840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LZG54_12860	COG2814	Major facilitator Superfamily
LZG54_12865	COG2814	Major facilitator Superfamily
LZG54_12915	COG0758	DNA mediated transformation
LZG54_12925	COG0697	spore germination
LZG54_12930	COG0386	Belongs to the glutathione peroxidase family
LZG54_12945	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LZG54_12995	COG1121	(ABC) transporter
LZG54_13000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LZG54_13015	COG2837	iron assimilation
LZG54_13105	COG2132	Multicopper oxidase
LZG54_13120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZG54_13150	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_13170	COG2217	Heavy metal translocating P-type atpase
LZG54_13175	COG3174	membrane
LZG54_13180	COG2205	protein histidine kinase activity
LZG54_13210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LZG54_13215	COG2026	Addiction module toxin, RelE StbE family
LZG54_13255	COG4372	Transposase
LZG54_13300	COG4372	Transposase
LZG54_13310	COG2963	transposase activity
LZG54_13350	COG3077	Addiction module antitoxin, RelB DinJ family
LZG54_13385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZG54_13390	COG0659	secondary active sulfate transmembrane transporter activity
LZG54_13400	COG3077	Addiction module antitoxin, RelB DinJ family
LZG54_13460	COG2814	Major facilitator Superfamily
LZG54_13470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LZG54_13470	COG0352	thiamine-phosphate diphosphorylase activity
LZG54_13470	COG0351	phosphomethylpyrimidine kinase
LZG54_13495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZG54_13500	COG3162	membrane
LZG54_13505	COG2205	protein histidine kinase activity
LZG54_13505	COG0784	Response regulator, receiver
LZG54_13515	COG0281	malic enzyme
LZG54_13550	COG0519	Catalyzes the synthesis of GMP from XMP
LZG54_13550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZG54_13555	COG0586	Pfam SNARE associated Golgi protein
LZG54_13570	COG1192	Involved in chromosome partitioning
LZG54_13575	COG3094	Invasion gene expression up-regulator, SirB
LZG54_13580	COG0271	Belongs to the BolA IbaG family
LZG54_13595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LZG54_13610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZG54_13625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LZG54_13635	COG1216	Glycosyl transferase, family 2
LZG54_13665	COG2244	polysaccharide biosynthetic process
LZG54_13680	COG1091	dTDP-4-dehydrorhamnose reductase activity
LZG54_13690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZG54_13695	COG1596	polysaccharide export
LZG54_13720	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LZG54_13750	COG1309	transcriptional regulator
LZG54_13760	COG2233	PERMEase
LZG54_13780	COG0129	dihydroxy-acid dehydratase activity
LZG54_13795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LZG54_13805	COG0733	neurotransmitter:sodium symporter activity
LZG54_13810	COG1012	belongs to the aldehyde dehydrogenase family
LZG54_13845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZG54_13855	COG0657	acetylesterase activity
LZG54_13865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LZG54_13885	COG2951	lytic endotransglycosylase activity
LZG54_13890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LZG54_13905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZG54_13915	COG2200	EAL domain
LZG54_13925	COG0861	Integral membrane protein TerC family
LZG54_13930	COG0402	S-adenosylhomocysteine deaminase activity
LZG54_13980	COG0706	membrane insertase activity
LZG54_13985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LZG54_13990	COG0594	ribonuclease P activity
LZG54_14145	COG3586	endonuclease activity
LZG54_14220	COG2826	transposase and inactivated derivatives, IS30 family
LZG54_14280	COG1660	Displays ATPase and GTPase activities
LZG54_14315	COG3173	Aminoglycoside phosphotransferase
LZG54_14320	COG0488	(ABC) transporter
LZG54_14330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LZG54_14350	COG1475	DNA binding
LZG54_14355	COG1192	Involved in chromosome partitioning
LZG54_14360	COG1570	exodeoxyribonuclease VII activity
LZG54_14375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LZG54_14410	COG1192	Involved in chromosome partitioning
LZG54_14415	COG1475	DNA binding
LZG54_14445	COG2184	nucleotidyltransferase activity
LZG54_14535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZG54_14555	COG3335	DDE superfamily endonuclease
LZG54_14570	COG1840	ABC-type Fe3 transport system, periplasmic component
LZG54_14580	COG0159	tryptophan synthase activity
LZG54_14590	COG1846	Transcriptional regulator
LZG54_14645	COG3077	Addiction module antitoxin, RelB DinJ family