locus-tag	class	description
LSO60_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LSO60_00010	COG0592	DNA-directed DNA polymerase activity
LSO60_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LSO60_00020	COG0187	DNA topoisomerase II activity
LSO60_00030	COG0488	(ABC) transporter
LSO60_00050	COG0316	Belongs to the HesB IscA family
LSO60_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LSO60_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LSO60_00095	COG0693	protein deglycase activity
LSO60_00110	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_00115	COG0733	neurotransmitter:sodium symporter activity
LSO60_00125	COG0428	transporter
LSO60_00130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LSO60_00135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LSO60_00150	COG1252	NADH dehydrogenase
LSO60_00155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LSO60_00170	COG2233	PERMEase
LSO60_00175	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LSO60_00180	COG1309	transcriptional regulator
LSO60_00185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO60_00200	COG0484	heat shock protein binding
LSO60_00205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LSO60_00215	COG2814	Major facilitator Superfamily
LSO60_00220	COG0583	DNA-binding transcription factor activity
LSO60_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO60_00235	COG1064	alcohol dehydrogenase
LSO60_00240	COG2818	Glycosylase
LSO60_00265	COG0412	Dienelactone hydrolase
LSO60_00270	COG5487	UPF0391 membrane protein
LSO60_00275	COG2983	Belongs to the UPF0260 family
LSO60_00290	COG2133	pyrroloquinoline quinone binding
LSO60_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LSO60_00305	COG2116	formate transmembrane transporter activity
LSO60_00310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LSO60_00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSO60_00325	COG1335	isochorismatase
LSO60_00330	COG0385	Bile acid
LSO60_00335	COG2388	GCN5-related N-acetyl-transferase
LSO60_00350	COG3121	Chaperone
LSO60_00355	COG3188	usher protein
LSO60_00365	COG3121	Chaperone
LSO60_00385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LSO60_00395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LSO60_00400	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LSO60_00405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LSO60_00410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LSO60_00425	COG3830	Belongs to the UPF0237 family
LSO60_00425	COG0560	Phosphoserine phosphatase
LSO60_00445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LSO60_00455	COG0688	phosphatidylethanolamine metabolic process
LSO60_00465	COG0300	oxidoreductase activity
LSO60_00495	COG0534	Mate efflux family protein
LSO60_00500	COG0436	Aminotransferase
LSO60_00505	COG2733	membrane
LSO60_00520	COG2918	glutathione biosynthetic process
LSO60_00535	COG3150	esterase
LSO60_00555	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LSO60_00560	COG4266	Belongs to the allantoicase family
LSO60_00565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO60_00575	COG1247	-acetyltransferase
LSO60_00625	COG3706	GGDEF domain
LSO60_00640	COG1393	Belongs to the ArsC family
LSO60_00645	COG0708	Exodeoxyribonuclease III
LSO60_00665	COG0189	ligase activity
LSO60_00670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSO60_00680	COG1181	Belongs to the D-alanine--D-alanine ligase family
LSO60_00685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LSO60_00695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LSO60_00730	COG2119	membrane
LSO60_00735	COG0426	domain, Protein
LSO60_00735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO60_00760	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_00780	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LSO60_00785	COG1476	TRANSCRIPTIONal
LSO60_00810	COG1902	pentaerythritol trinitrate reductase activity
LSO60_00815	COG1519	Transferase
LSO60_00825	COG0668	transmembrane transport
LSO60_00835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSO60_00865	COG0004	ammonium transporteR
LSO60_00880	COG2205	protein histidine kinase activity
LSO60_00880	COG0784	Response regulator, receiver
LSO60_00885	COG3162	membrane
LSO60_00890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSO60_00910	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_00980	COG1192	Involved in chromosome partitioning
LSO60_00995	COG0586	Pfam SNARE associated Golgi protein
LSO60_01000	COG2259	Doxx family
LSO60_01005	COG3111	PFAM Bacterial OB fold (BOF) protein
LSO60_01010	COG0519	Catalyzes the synthesis of GMP from XMP
LSO60_01010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LSO60_01060	COG0018	arginyl-trna synthetase
LSO60_01070	COG0281	malic enzyme
LSO60_01080	COG3409	Peptidoglycan-binding domain 1 protein
LSO60_01080	COG1388	LysM domain
LSO60_01080	COG5632	N-Acetylmuramoyl-L-alanine amidase
LSO60_01125	COG1280	lysine exporter protein (LysE YggA)
LSO60_01130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LSO60_01135	COG1121	(ABC) transporter
LSO60_01155	COG0356	it plays a direct role in the translocation of protons across the membrane
LSO60_01185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LSO60_01190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LSO60_01215	COG0386	Belongs to the glutathione peroxidase family
LSO60_01225	COG2814	Major facilitator Superfamily
LSO60_01230	COG1309	transcriptional regulator
LSO60_01235	COG0697	spore germination
LSO60_01275	COG3845	ABC transporter
LSO60_01280	COG4603	Belongs to the binding-protein-dependent transport system permease family
LSO60_01285	COG1079	Belongs to the binding-protein-dependent transport system permease family
LSO60_01290	COG0009	L-threonylcarbamoyladenylate synthase
LSO60_01295	COG0758	DNA mediated transformation
LSO60_01300	COG1652	LysM domain
LSO60_01330	COG1309	transcriptional regulator
LSO60_01380	COG0477	Major facilitator Superfamily
LSO60_01385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSO60_01405	COG1253	flavin adenine dinucleotide binding
LSO60_01415	COG2860	membrane
LSO60_01420	COG0477	Major facilitator Superfamily
LSO60_01430	COG0318	PFAM AMP-dependent synthetase and ligase
LSO60_01445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LSO60_01500	COG4372	Transposase
LSO60_01525	COG0633	Ferredoxin
LSO60_01565	COG2814	Major facilitator Superfamily
LSO60_01580	COG0259	pyridoxamine-phosphate oxidase activity
LSO60_01595	COG0789	Transcriptional regulator
LSO60_01605	COG0640	Transcriptional regulator
LSO60_01610	COG3293	Transposase
LSO60_01620	COG1230	cation diffusion facilitator family transporter
LSO60_01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO60_01670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LSO60_01705	COG0347	Belongs to the P(II) protein family
LSO60_01710	COG0004	ammonium transporteR
LSO60_01715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LSO60_01720	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSO60_01720	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSO60_01755	COG0795	lipopolysaccharide-transporting ATPase activity
LSO60_01760	COG0795	lipopolysaccharide-transporting ATPase activity
LSO60_01765	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LSO60_01770	COG0793	Belongs to the peptidase S41A family
LSO60_01785	COG2197	response regulator
LSO60_01795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LSO60_01805	COG3547	Transposase (IS116 IS110 IS902 family)
LSO60_01870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LSO60_01875	COG4974	Belongs to the 'phage' integrase family
LSO60_01895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LSO60_01900	COG0772	Belongs to the SEDS family
LSO60_01905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LSO60_01910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LSO60_01915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LSO60_01920	COG0494	nUDIX hydrolase
LSO60_01950	COG3275	phosphorelay sensor kinase activity
LSO60_01960	COG0181	hydroxymethylbilane synthase activity
LSO60_02005	COG1716	ATPase activity
LSO60_02040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LSO60_02060	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LSO60_02065	COG0081	regulation of translation
LSO60_02080	COG0085	RNA polymerase activity
LSO60_02085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LSO60_02120	COG0326	Molecular chaperone. Has ATPase activity
LSO60_02150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LSO60_02175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSO60_02180	COG1758	RNA polymerase activity
LSO60_02185	COG0194	GDP metabolic process
LSO60_02230	COG0228	four-way junction DNA binding
LSO60_02235	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LSO60_02245	COG0335	large ribosomal subunit rRNA binding
LSO60_02250	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LSO60_02255	COG5380	lipid catabolic process
LSO60_02260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LSO60_02280	COG5006	permease, DMT superfamily
LSO60_02285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSO60_02290	COG0277	FAD linked oxidase domain protein
LSO60_02310	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LSO60_02315	COG2249	NAD(P)H dehydrogenase (quinone) activity
LSO60_02325	COG2814	Major facilitator Superfamily
LSO60_02330	COG1289	transmembrane transporter activity
LSO60_02355	COG0628	permease
LSO60_02360	COG1192	Involved in chromosome partitioning
LSO60_02405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LSO60_02420	COG0583	DNA-binding transcription factor activity
LSO60_02440	COG0752	glycyl-tRNA synthetase alpha subunit
LSO60_02455	COG0517	IMP dehydrogenase activity
LSO60_02460	COG1983	PspC domain protein
LSO60_02470	COG1960	acyl-CoA dehydrogenase activity
LSO60_02485	COG2885	chlorophyll binding
LSO60_02495	COG0408	coproporphyrinogen oxidase activity
LSO60_02500	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LSO60_02505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LSO60_02520	COG0513	Belongs to the DEAD box helicase family
LSO60_02530	COG1127	ABC transporter
LSO60_02535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LSO60_02555	COG0598	Magnesium transport protein CorA
LSO60_02565	COG0494	nUDIX hydrolase
LSO60_02570	COG1040	competence protein
LSO60_02575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LSO60_02590	COG2937	Belongs to the GPAT DAPAT family
LSO60_02595	COG1946	Acyl-CoA thioesterase
LSO60_02600	COG1301	dicarboxylic acid transport
LSO60_02615	COG1959	2 iron, 2 sulfur cluster binding
LSO60_02620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LSO60_02620	COG1017	nitric oxide dioxygenase activity
LSO60_02625	COG0433	COG0433 Predicted ATPase
LSO60_02640	COG0051	transcription antitermination factor activity, RNA binding
LSO60_02645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LSO60_02650	COG0088	Forms part of the polypeptide exit tunnel
LSO60_02665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LSO60_02670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LSO60_02680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LSO60_02690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LSO60_02695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LSO60_02700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LSO60_02705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LSO60_02715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LSO60_02720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LSO60_02730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LSO60_02755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LSO60_02765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LSO60_02770	COG0202	RNA polymerase activity
LSO60_02775	COG0203	ribosomal protein L17
LSO60_02780	COG2072	flavoprotein involved in K transport
LSO60_02785	COG1960	acyl-CoA dehydrogenase activity
LSO60_02790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LSO60_02820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LSO60_02825	COG0339	signal peptide processing
LSO60_02835	COG0557	exoribonuclease II activity
LSO60_02860	COG5002	protein histidine kinase activity
LSO60_02880	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSO60_02890	COG2814	Major facilitator Superfamily
LSO60_02895	COG0583	DNA-binding transcription factor activity
LSO60_02910	COG1295	ribonuclease BN
LSO60_02945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LSO60_02950	COG1702	phosphate starvation-inducible protein PhoH
LSO60_02955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LSO60_02960	COG1196	nuclear chromosome segregation
LSO60_02960	COG0739	heme binding
LSO60_02960	COG0741	lytic transglycosylase activity
LSO60_02970	COG0039	L-malate dehydrogenase activity
LSO60_02990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LSO60_02995	COG1183	phosphatidylcholine synthase activity
LSO60_03030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LSO60_03055	COG1607	acyl-coa hydrolase
LSO60_03060	COG1956	GAF domain-containing protein
LSO60_03090	COG0183	Belongs to the thiolase family
LSO60_03105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LSO60_03120	COG2832	Protein of unknown function (DUF454)
LSO60_03125	COG1376	ErfK ybiS ycfS ynhG family protein
LSO60_03170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LSO60_03180	COG1289	transmembrane transporter activity
LSO60_03185	COG2814	Major facilitator Superfamily
LSO60_03200	COG0786	glutamate:sodium symporter activity
LSO60_03205	COG1115	amino acid carrier protein
LSO60_03210	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSO60_03225	COG2824	Alkylphosphonate utilization operon protein PhnA
LSO60_03230	COG0494	nUDIX hydrolase
LSO60_03235	COG3422	double-strand break repair
LSO60_03250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSO60_03260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LSO60_03275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LSO60_03275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LSO60_03280	COG0730	response to heat
LSO60_03290	COG1196	nuclear chromosome segregation
LSO60_03300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LSO60_03315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LSO60_03330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LSO60_03330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LSO60_03340	COG4106	trans-aconitate 2-methyltransferase activity
LSO60_03360	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LSO60_03365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LSO60_03375	COG0009	L-threonylcarbamoyladenylate synthase
LSO60_03380	COG3101	peptidyl-lysine hydroxylation
LSO60_03385	COG1399	metal-binding, possibly nucleic acid-binding protein
LSO60_03400	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_03410	COG1652	LysM domain
LSO60_03415	COG0352	thiamine-phosphate diphosphorylase activity
LSO60_03415	COG0351	phosphomethylpyrimidine kinase
LSO60_03415	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LSO60_03435	COG1981	membrane
LSO60_03460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LSO60_03465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LSO60_03475	COG0456	acetyltransferase
LSO60_03480	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LSO60_03485	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LSO60_03490	COG0500	methyltransferase
LSO60_03495	COG0492	ferredoxin-NADP+ reductase activity
LSO60_03500	COG1674	ftsk spoiiie
LSO60_03500	COG0531	amino acid
LSO60_03510	COG1280	lysine exporter protein (LysE YggA)
LSO60_03520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LSO60_03525	COG2894	cell division
LSO60_03530	COG0850	regulation of cytokinetic process
LSO60_03540	COG0204	Acyl-transferase
LSO60_03545	COG2885	chlorophyll binding
LSO60_03555	COG0756	dUTP diphosphatase activity
LSO60_03560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LSO60_03565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LSO60_03575	COG0121	glutamine amidotransferase
LSO60_03590	COG2914	Belongs to the UPF0125 (RnfH) family
LSO60_03595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LSO60_03600	COG0735	belongs to the Fur family
LSO60_03620	COG1968	undecaprenyl-diphosphatase activity
LSO60_03640	COG0420	3'-5' exonuclease activity
LSO60_03665	COG2050	protein possibly involved in aromatic compounds catabolism
LSO60_03670	COG1566	PFAM secretion protein HlyD family protein
LSO60_03675	COG2814	Major facilitator Superfamily
LSO60_03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO60_03715	COG1877	trehalose-phosphatase activity
LSO60_03720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LSO60_03725	COG2223	nitrite transmembrane transporter activity
LSO60_03735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LSO60_03740	COG1301	dicarboxylic acid transport
LSO60_03745	COG0436	Aminotransferase
LSO60_03750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LSO60_03755	COG0583	DNA-binding transcription factor activity
LSO60_03785	COG2223	nitrite transmembrane transporter activity
LSO60_03805	COG0577	efflux transmembrane transporter activity
LSO60_03805	COG1136	(ABC) transporter
LSO60_03810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO60_03835	COG0028	Belongs to the TPP enzyme family
LSO60_03845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LSO60_03860	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LSO60_03875	COG0084	hydrolase, TatD family'
LSO60_03885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LSO60_03895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LSO60_03905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSO60_03925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LSO60_03945	COG1414	Transcriptional regulator
LSO60_03965	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_03975	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSO60_03980	COG2271	Major facilitator Superfamily
LSO60_03995	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_04000	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LSO60_04005	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_04010	COG0028	Belongs to the TPP enzyme family
LSO60_04025	COG1120	ATPase activity
LSO60_04030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LSO60_04055	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LSO60_04060	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_04065	COG1309	transcriptional regulator
LSO60_04070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LSO60_04080	COG1607	acyl-coa hydrolase
LSO60_04090	COG2009	succinate dehydrogenase
LSO60_04095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LSO60_04100	COG1053	succinate dehydrogenase
LSO60_04105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LSO60_04120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LSO60_04125	COG0045	succinate-CoA ligase (ADP-forming) activity
LSO60_04140	COG1649	PFAM Uncharacterised BCR, COG1649
LSO60_04140	COG0726	polysaccharide deacetylase
LSO60_04145	COG1215	transferase activity, transferring glycosyl groups
LSO60_04160	COG2268	Band 7 protein
LSO60_04165	COG1585	Membrane protein implicated in regulation of membrane protease activity
LSO60_04175	COG2354	Protein conserved in bacteria
LSO60_04180	COG2321	neutral zinc metallopeptidase
LSO60_04185	COG0531	amino acid
LSO60_04200	COG0321	lipoyl(octanoyl) transferase activity
LSO60_04225	COG0500	methyltransferase
LSO60_04230	COG0586	Pfam SNARE associated Golgi protein
LSO60_04245	COG1054	Belongs to the UPF0176 family
LSO60_04265	COG0193	aminoacyl-tRNA hydrolase activity
LSO60_04275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LSO60_04315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LSO60_04365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LSO60_04375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LSO60_04400	COG1492	cobalamin metabolic process
LSO60_04405	COG0175	sulfate reduction
LSO60_04415	COG2851	Citrate transporter
LSO60_04435	COG0439	Biotin carboxylase
LSO60_04445	COG0864	Transcriptional regulator
LSO60_04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LSO60_04475	COG1116	anion transmembrane transporter activity
LSO60_04485	COG1253	flavin adenine dinucleotide binding
LSO60_04505	COG3015	lipoprotein NlpE involved in copper resistance
LSO60_04520	COG0829	nickel cation binding
LSO60_04525	COG0831	urea catabolic process
LSO60_04530	COG0832	Belongs to the urease beta subunit family
LSO60_04535	COG0804	urea catabolic process
LSO60_04540	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LSO60_04545	COG0830	nickel cation binding
LSO60_04550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LSO60_04575	COG0742	ribosomal rna small subunit methyltransferase
LSO60_04580	COG0768	penicillin binding
LSO60_04595	COG0563	adenylate kinase activity
LSO60_04605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LSO60_04610	COG2878	Part of a membrane complex involved in electron transport
LSO60_04615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LSO60_04625	COG3384	dioxygenase
LSO60_04640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LSO60_04665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO60_04675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LSO60_04685	COG1671	Belongs to the UPF0178 family
LSO60_04705	COG1136	(ABC) transporter
LSO60_04710	COG2333	competence protein COMEC
LSO60_04710	COG0658	competence protein
LSO60_04730	COG1113	amino acid transport
LSO60_04735	COG2828	Protein conserved in bacteria
LSO60_04745	COG0142	geranyltranstransferase activity
LSO60_04760	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSO60_04770	COG2814	Major facilitator Superfamily
LSO60_04775	COG0745	RESPONSE REGULATOR receiver
LSO60_04790	COG0004	ammonium transporteR
LSO60_04805	COG0525	valine-tRNA ligase activity
LSO60_04815	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_04820	COG0393	Putative heavy-metal-binding
LSO60_04825	COG0393	Putative heavy-metal-binding
LSO60_04830	COG1538	Outer membrane efflux protein
LSO60_04840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO60_04845	COG0671	phosphoesterase, PA-phosphatase related
LSO60_04860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LSO60_04865	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LSO60_04875	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LSO60_04885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LSO60_04890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LSO60_04890	COG1648	precorrin-2 dehydrogenase activity
LSO60_04895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LSO60_04905	COG1733	regulation of RNA biosynthetic process
LSO60_04930	COG0583	DNA-binding transcription factor activity
LSO60_04940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO60_04945	COG1773	rubredoxin
LSO60_04950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LSO60_04965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LSO60_04985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LSO60_04985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LSO60_05000	COG0523	cobalamin synthesis protein
LSO60_05010	COG4681	YaeQ
LSO60_05025	COG1649	PFAM Uncharacterised BCR, COG1649
LSO60_05025	COG0726	polysaccharide deacetylase
LSO60_05030	COG1215	transferase activity, transferring glycosyl groups
LSO60_05055	COG0400	carboxylic ester hydrolase activity
LSO60_05070	COG0561	phosphatase activity
LSO60_05075	COG0242	peptide deformylase activity
LSO60_05080	COG2066	Belongs to the glutaminase family
LSO60_05090	COG2223	nitrite transmembrane transporter activity
LSO60_05105	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_05125	COG0306	phosphate transporter
LSO60_05145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LSO60_05185	COG0288	reversible hydration of carbon dioxide
LSO60_05195	COG4181	ATPase activity
LSO60_05200	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LSO60_05210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LSO60_05220	COG0589	response to stress
LSO60_05230	COG0589	response to stress
LSO60_05250	COG0505	Belongs to the CarA family
LSO60_05270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LSO60_05275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSO60_05280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LSO60_05300	COG1929	Belongs to the glycerate kinase type-1 family
LSO60_05320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LSO60_05345	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LSO60_05350	COG1597	lipid kinase activity
LSO60_05365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LSO60_05370	COG0459	protein refolding
LSO60_05375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LSO60_05380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LSO60_05385	COG1045	serine acetyltransferase
LSO60_05395	COG2188	Transcriptional regulator
LSO60_05400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LSO60_05425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO60_05430	COG2239	Acts as a magnesium transporter
LSO60_05440	COG0501	Belongs to the peptidase M48B family
LSO60_05445	COG1196	nuclear chromosome segregation
LSO60_05445	COG0741	lytic transglycosylase activity
LSO60_05445	COG0739	heme binding
LSO60_05450	COG0037	tRNA processing
LSO60_05465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LSO60_05475	COG0583	DNA-binding transcription factor activity
LSO60_05490	COG1131	(ABC) transporter
LSO60_05495	COG0842	Transport permease protein
LSO60_05500	COG0842	Transport permease protein
LSO60_05510	COG0583	DNA-binding transcription factor activity
LSO60_05515	COG0473	3-isopropylmalate dehydrogenase activity
LSO60_05525	COG0657	acetylesterase activity
LSO60_05530	COG4638	Rieske (2fe-2S)
LSO60_05535	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_05550	COG0475	glutathione-regulated potassium exporter activity
LSO60_05550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LSO60_05585	COG1741	Belongs to the pirin family
LSO60_05595	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LSO60_05600	COG3739	integral membrane protein
LSO60_05610	COG0586	Pfam SNARE associated Golgi protein
LSO60_05615	COG0302	gtp cyclohydrolase
LSO60_05625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LSO60_05645	COG0134	indole-3-glycerol-phosphate synthase activity
LSO60_05650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LSO60_05655	COG0512	Glutamine amidotransferase of anthranilate synthase
LSO60_05890	COG0582	viral genome integration into host DNA
LSO60_05895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LSO60_05900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LSO60_05905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSO60_05910	COG1067	ATP-dependent peptidase activity
LSO60_05925	COG0254	rRNA binding
LSO60_05930	COG0583	DNA-binding transcription factor activity
LSO60_05935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LSO60_05940	COG4208	sulfate ABC transporter
LSO60_05945	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LSO60_05955	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LSO60_05960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LSO60_05965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LSO60_05970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LSO60_05980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSO60_05985	COG0174	glutamine synthetase
LSO60_05995	COG0481	GTPase activity
LSO60_06000	COG0681	Belongs to the peptidase S26 family
LSO60_06010	COG0571	ribonuclease III activity
LSO60_06015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LSO60_06025	COG1381	Involved in DNA repair and RecF pathway recombination
LSO60_06030	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LSO60_06045	COG3161	chorismate lyase activity
LSO60_06050	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LSO60_06060	COG1301	dicarboxylic acid transport
LSO60_06080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LSO60_06085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LSO60_06105	COG3634	alkyl hydroperoxide reductase activity
LSO60_06110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LSO60_06115	COG0826	peptidase U32
LSO60_06120	COG3384	dioxygenase
LSO60_06125	COG1335	isochorismatase
LSO60_06135	COG1720	tRNA m6t6A37 methyltransferase activity
LSO60_06140	COG3706	GGDEF domain
LSO60_06145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LSO60_06160	COG0642	Histidine kinase
LSO60_06170	COG0494	nUDIX hydrolase
LSO60_06180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LSO60_06185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LSO60_06190	COG3139	Protein of unknown function (DUF1315)
LSO60_06195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LSO60_06200	COG1301	dicarboxylic acid transport
LSO60_06205	COG0659	secondary active sulfate transmembrane transporter activity
LSO60_06215	COG2252	PERMEase
LSO60_06220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LSO60_06235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LSO60_06250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LSO60_06265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LSO60_06270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LSO60_06285	COG0667	Aldo Keto reductase
LSO60_06295	COG1765	OsmC-like protein
LSO60_06320	COG0116	Belongs to the methyltransferase superfamily
LSO60_06320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LSO60_06325	COG0540	Belongs to the ATCase OTCase family
LSO60_06355	COG2995	paraquat-inducible protein a
LSO60_06360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LSO60_06360	COG3008	intermembrane lipid transfer
LSO60_06370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LSO60_06370	COG0047	phosphoribosylformylglycinamidine synthase activity
LSO60_06380	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_06400	COG1024	Enoyl-CoA hydratase
LSO60_06405	COG1051	belongs to the nudix hydrolase family
LSO60_06405	COG1056	cytidyltransferase-related domain
LSO60_06410	COG2353	YceI-like domain
LSO60_06415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LSO60_06425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LSO60_06430	COG0602	queuosine metabolic process
LSO60_06440	COG4625	pathogenesis
LSO60_06455	COG1509	lysine 2,3-aminomutase activity
LSO60_06460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LSO60_06465	COG1966	Carbon starvation protein
LSO60_06470	COG2879	small protein
LSO60_06475	COG0714	Associated with various cellular activities
LSO60_06485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO60_06495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO60_06505	COG0596	Alpha beta hydrolase
LSO60_06510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LSO60_06535	COG3706	GGDEF domain
LSO60_06575	COG0436	Aminotransferase
LSO60_06580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LSO60_06585	COG0386	Belongs to the glutathione peroxidase family
LSO60_06610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LSO60_06615	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LSO60_06620	COG1942	4-Oxalocrotonate Tautomerase
LSO60_06635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LSO60_06640	COG0012	GTP binding
LSO60_06645	COG2011	ABC-type metal ion transport system permease component
LSO60_06650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LSO60_06655	COG1464	Belongs to the NlpA lipoprotein family
LSO60_06680	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_06685	COG0471	metal ion transport
LSO60_06690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LSO60_06705	COG0583	DNA-binding transcription factor activity
LSO60_06715	COG2707	UPF0756 membrane protein
LSO60_06725	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LSO60_06755	COG0564	pseudouridine synthase activity
LSO60_06760	COG0802	atpase or kinase
LSO60_06765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LSO60_06770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LSO60_06775	COG1923	regulation of RNA biosynthetic process
LSO60_06780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSO60_06785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LSO60_06795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LSO60_06800	COG0357	Ribosomal RNA small subunit methyltransferase G
LSO60_06805	COG1192	Involved in chromosome partitioning
LSO60_06810	COG1475	DNA binding
LSO60_06815	COG0811	peptide transport
LSO60_06825	COG1132	(ABC) transporter
LSO60_06830	COG1663	tetraacyldisaccharide 4'-kinase activity
LSO60_06850	COG0084	hydrolase, TatD family'
LSO60_06905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LSO60_06915	COG0776	regulation of translation
LSO60_06925	COG0284	orotidine-5'-phosphate decarboxylase activity
LSO60_06945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LSO60_07105	COG5410	chromosome segregation
LSO60_07255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSO60_07265	COG0582	viral genome integration into host DNA
LSO60_07280	COG1253	flavin adenine dinucleotide binding
LSO60_07295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LSO60_07305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LSO60_07310	COG0730	response to heat
LSO60_07330	COG4773	Receptor
LSO60_07335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LSO60_07370	COG0515	serine threonine protein kinase
LSO60_07370	COG2815	serine threonine protein kinase
LSO60_07410	COG2011	ABC-type metal ion transport system permease component
LSO60_07415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LSO60_07420	COG1464	Belongs to the NlpA lipoprotein family
LSO60_07430	COG0138	bifunctional purine biosynthesis protein purh
LSO60_07435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LSO60_07460	COG0445	tRNA wobble uridine modification
LSO60_07470	COG2308	Evidence 4 Homologs of previously reported genes of
LSO60_07480	COG1305	Transglutaminase-like
LSO60_07495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LSO60_07500	COG0305	Participates in initiation and elongation during chromosome replication
LSO60_07505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LSO60_07540	COG0552	protein localization to endoplasmic reticulum
LSO60_07560	COG4890	Cyd operon protein YbgT
LSO60_07565	COG1294	oxidase, subunit
LSO60_07580	COG1585	Membrane protein implicated in regulation of membrane protease activity
LSO60_07590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSO60_07605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LSO60_07610	COG0569	domain protein
LSO60_07615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LSO60_07620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LSO60_07635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LSO60_07645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LSO60_07650	COG0542	response to heat
LSO60_07675	COG0765	amino acid transport
LSO60_07680	COG0765	amino acid transport
LSO60_07685	COG1126	abc transporter atp-binding protein
LSO60_07700	COG0217	transcriptional regulatory protein
LSO60_07715	COG2193	ferroxidase activity
LSO60_07730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LSO60_07740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LSO60_07740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LSO60_07770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LSO60_07775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LSO60_07790	COG2353	YceI-like domain
LSO60_07800	COG0505	Belongs to the CarA family
LSO60_07820	COG1454	alcohol dehydrogenase
LSO60_07825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSO60_07835	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LSO60_07840	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LSO60_07855	COG0308	aminopeptidase N
LSO60_07865	COG0589	response to stress
LSO60_07880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LSO60_07890	COG3135	benzoate transporter
LSO60_07900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LSO60_07930	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_07935	COG2030	dehydratase
LSO60_07965	COG0824	Thioesterase
LSO60_07970	COG1454	alcohol dehydrogenase
LSO60_07975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LSO60_07980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LSO60_08000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LSO60_08030	COG0316	Belongs to the HesB IscA family
LSO60_08035	COG0822	iron-sulfur transferase activity
LSO60_08065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSO60_08070	COG2814	Major facilitator Superfamily
LSO60_08130	COG0024	Methionine aminopeptidase
LSO60_08135	COG0583	DNA-binding transcription factor activity
LSO60_08140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSO60_08150	COG0583	DNA-binding transcription factor activity
LSO60_08155	COG1960	acyl-CoA dehydrogenase activity
LSO60_08160	COG2814	Major facilitator Superfamily
LSO60_08165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LSO60_08200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LSO60_08210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LSO60_08220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LSO60_08235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LSO60_08250	COG1346	cytolysis
LSO60_08255	COG1380	Effector of murein hydrolase LrgA
LSO60_08260	COG0583	DNA-binding transcription factor activity
LSO60_08300	COG0644	oxidoreductase
LSO60_08300	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LSO60_08305	COG2814	Major facilitator Superfamily
LSO60_08320	COG2814	Major facilitator Superfamily
LSO60_08335	COG0183	Belongs to the thiolase family
LSO60_08340	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSO60_08345	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_08350	COG1024	Enoyl-CoA hydratase
LSO60_08355	COG1960	acyl-CoA dehydrogenase activity
LSO60_08360	COG2814	Major facilitator Superfamily
LSO60_08365	COG2814	Major facilitator Superfamily
LSO60_08375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LSO60_08385	COG2814	Major facilitator Superfamily
LSO60_08395	COG1960	acyl-CoA dehydrogenase activity
LSO60_08400	COG1024	Enoyl-CoA hydratase
LSO60_08405	COG0235	Class ii aldolase
LSO60_08410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSO60_08415	COG0583	DNA-binding transcription factor activity
LSO60_08420	COG0477	Major facilitator Superfamily
LSO60_08425	COG1414	Transcriptional regulator
LSO60_08430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LSO60_08435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LSO60_08440	COG0183	Belongs to the thiolase family
LSO60_08445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LSO60_08450	COG0596	Alpha beta hydrolase
LSO60_08455	COG2271	Major facilitator Superfamily
LSO60_08460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LSO60_08465	COG3485	protocatechuate 3,4-dioxygenase
LSO60_08470	COG3485	protocatechuate 3,4-dioxygenase
LSO60_08475	COG0710	3-dehydroquinate dehydratase activity
LSO60_08480	COG3420	alginic acid biosynthetic process
LSO60_08485	COG3659	wide pore channel activity
LSO60_08490	COG4993	Dehydrogenase
LSO60_08495	COG1414	Transcriptional regulator
LSO60_08500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO60_08515	COG1846	Transcriptional regulator
LSO60_08520	COG0583	DNA-binding transcription factor activity
LSO60_08525	COG1027	Aspartate ammonia-lyase
LSO60_08540	COG1595	DNA-templated transcription, initiation
LSO60_08545	COG1538	Outer membrane efflux protein
LSO60_08555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO60_08590	COG0640	Transcriptional regulator
LSO60_08605	COG3122	Protein conserved in bacteria
LSO60_08610	COG0668	transmembrane transport
LSO60_08615	COG1132	(ABC) transporter
LSO60_08630	COG0509	glycine decarboxylation via glycine cleavage system
LSO60_08635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LSO60_08640	COG0488	(ABC) transporter
LSO60_08645	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LSO60_08655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LSO60_08695	COG1960	acyl-CoA dehydrogenase activity
LSO60_08705	COG2194	sulfuric ester hydrolase activity
LSO60_08725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LSO60_08730	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LSO60_08750	COG0697	spore germination
LSO60_08755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO60_08765	COG0725	ABC transporter, periplasmic molybdate-binding protein
LSO60_08770	COG0303	'Molybdopterin
LSO60_08775	COG0521	Mo-molybdopterin cofactor biosynthetic process
LSO60_08775	COG0315	cyclic pyranopterin monophosphate synthase activity
LSO60_08800	COG0243	molybdopterin cofactor binding
LSO60_08805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO60_08810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO60_08810	COG2146	nitrite reductase [NAD(P)H] activity
LSO60_08815	COG2223	nitrite transmembrane transporter activity
LSO60_08820	COG0745	RESPONSE REGULATOR receiver
LSO60_08825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO60_08825	COG1116	anion transmembrane transporter activity
LSO60_08835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO60_08840	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LSO60_08850	COG0148	phosphopyruvate hydratase activity
LSO60_08860	COG0504	CTP synthase activity
LSO60_08880	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSO60_08880	COG1902	pentaerythritol trinitrate reductase activity
LSO60_08890	COG2267	carboxylic ester hydrolase activity
LSO60_08895	COG0477	Major facilitator Superfamily
LSO60_08900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LSO60_08905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSO60_08915	COG0506	proline dehydrogenase activity
LSO60_08915	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LSO60_08915	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LSO60_08920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LSO60_08925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LSO60_08935	COG3698	Phosphodiester glycosidase
LSO60_08950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LSO60_08970	COG0697	spore germination
LSO60_08975	COG0191	fructose-bisphosphate aldolase activity
LSO60_08985	COG0126	phosphoglycerate kinase activity
LSO60_08995	COG0424	maF-like protein
LSO60_09005	COG2850	peptidyl-arginine hydroxylation
LSO60_09010	COG0069	glutamate synthase activity
LSO60_09025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LSO60_09030	COG0702	epimerase
LSO60_09035	COG0268	Binds directly to 16S ribosomal RNA
LSO60_09040	COG3594	Acyltransferase
LSO60_09050	COG1218	3'(2'),5'-bisphosphate nucleotidase
LSO60_09055	COG1011	Hydrolase
LSO60_09060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LSO60_09070	COG2137	regulation of response to DNA damage stimulus
LSO60_09085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LSO60_09095	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LSO60_09120	COG0575	Belongs to the CDS family
LSO60_09125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LSO60_09130	COG0233	cytoplasmic translational termination
LSO60_09135	COG0528	UMP kinase activity
LSO60_09145	COG3852	Histidine kinase
LSO60_09150	COG2204	response regulator
LSO60_09160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSO60_09370	COG1484	DNA-dependent DNA replication
LSO60_09415	COG4197	protein conserved in bacteria, prophage-related
LSO60_09505	COG0729	surface antigen
LSO60_09515	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LSO60_09525	COG0745	RESPONSE REGULATOR receiver
LSO60_09530	COG2205	protein histidine kinase activity
LSO60_09535	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LSO60_09540	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LSO60_09545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LSO60_09555	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LSO60_09580	COG1960	acyl-CoA dehydrogenase activity
LSO60_09585	COG1960	acyl-CoA dehydrogenase activity
LSO60_09595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO60_09600	COG2207	Transcriptional regulator
LSO60_09625	COG1968	undecaprenyl-diphosphatase activity
LSO60_09630	COG3042	response to heat
LSO60_09670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO60_09675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSO60_09690	COG2890	protein-(glutamine-N5) methyltransferase activity
LSO60_09695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LSO60_09705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO60_09710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LSO60_09725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LSO60_09730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LSO60_09735	COG1845	cytochrome c oxidase, subunit III
LSO60_09740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LSO60_09750	COG0360	Binds together with S18 to 16S ribosomal RNA
LSO60_09755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LSO60_09770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSO60_09780	COG3100	YcgL domain-containing protein
LSO60_09790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LSO60_09820	COG0537	adenosine 5'-monophosphoramidase activity
LSO60_09840	COG1610	YqeY-like protein
LSO60_09875	COG1286	toxin biosynthetic process
LSO60_09880	COG0167	dihydroorotate dehydrogenase activity
LSO60_09905	COG0778	Nitroreductase
LSO60_09915	COG0513	Belongs to the DEAD box helicase family
LSO60_09955	COG0625	glutathione transferase activity
LSO60_09975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LSO60_09980	COG1960	acyl-CoA dehydrogenase activity
LSO60_09990	COG3706	GGDEF domain
LSO60_10000	COG4716	Myosin-crossreactive antigen
LSO60_10015	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LSO60_10020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LSO60_10025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LSO60_10045	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LSO60_10050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LSO60_10065	COG0583	DNA-binding transcription factor activity
LSO60_10075	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LSO60_10090	COG1686	Belongs to the peptidase S11 family
LSO60_10095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LSO60_10110	COG0482	sulfurtransferase activity
LSO60_10115	COG2915	High frequency lysogenization protein hflD homolog
LSO60_10130	COG0616	signal peptide processing
LSO60_10135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LSO60_10145	COG0573	inorganic phosphate transmembrane transporter activity
LSO60_10150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LSO60_10155	COG0076	glutamate decarboxylase activity
LSO60_10160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LSO60_10180	COG1309	transcriptional regulator
LSO60_10185	COG0783	Belongs to the Dps family
LSO60_10195	COG0564	pseudouridine synthase activity
LSO60_10200	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LSO60_10210	COG0352	thiamine-phosphate diphosphorylase activity
LSO60_10220	COG1686	Belongs to the peptidase S11 family
LSO60_10230	COG0589	response to stress
LSO60_10240	COG0671	phosphoesterase, PA-phosphatase related
LSO60_10250	COG2194	sulfuric ester hydrolase activity
LSO60_10255	COG0745	RESPONSE REGULATOR receiver
LSO60_10260	COG0642	Histidine kinase
LSO60_10280	COG0778	Nitroreductase
LSO60_10285	COG4221	oxidoreductase activity
LSO60_10305	COG1131	(ABC) transporter
LSO60_10310	COG0842	Transport permease protein
LSO60_10315	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LSO60_10315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LSO60_10325	COG0772	Belongs to the SEDS family
LSO60_10330	COG2951	lytic endotransglycosylase activity
LSO60_10365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LSO60_10370	COG0052	Belongs to the universal ribosomal protein uS2 family
LSO60_10375	COG0024	Methionine aminopeptidase
LSO60_10390	COG2175	clavaminate synthase activity
LSO60_10400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LSO60_10420	COG4969	Belongs to the N-Me-Phe pilin family
LSO60_10445	COG4968	Prepilin-type N-terminal cleavage methylation domain
LSO60_10455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LSO60_10465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LSO60_10475	COG4122	O-methyltransferase activity
LSO60_10505	COG1538	Outer membrane efflux protein
LSO60_10525	COG1137	ATPase activity
LSO60_10530	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LSO60_10540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LSO60_10560	COG4993	Dehydrogenase
LSO60_10565	COG2175	clavaminate synthase activity
LSO60_10570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO60_10575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LSO60_10580	COG4521	taurine ABC transporter
LSO60_10595	COG2255	four-way junction helicase activity
LSO60_10600	COG0824	Thioesterase
LSO60_10620	COG0823	Involved in the tonB-independent uptake of proteins
LSO60_10640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LSO60_10660	COG5001	Diguanylate cyclase
LSO60_10660	COG4251	negative regulation of phosphorylation
LSO60_10660	COG3706	GGDEF domain
LSO60_10660	COG2203	Gaf domain
LSO60_10665	COG0418	dihydroorotase activity
LSO60_10670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LSO60_10680	COG0833	amino acid
LSO60_10690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LSO60_10695	COG0243	molybdopterin cofactor binding
LSO60_10705	COG1643	Atp-dependent helicase
LSO60_10750	COG3022	response to hydroperoxide
LSO60_10755	COG2195	Cleaves the N-terminal amino acid of tripeptides
LSO60_10765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LSO60_10790	COG1764	response to oxidative stress
LSO60_10810	COG0632	four-way junction helicase activity
LSO60_10815	COG4302	ethanolamine ammonia-lyase activity
LSO60_10820	COG4303	Ethanolamine ammonia lyase large subunit
LSO60_10825	COG0531	amino acid
LSO60_10830	COG2070	2-Nitropropane dioxygenase
LSO60_10835	COG2318	DinB family
LSO60_10840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSO60_10855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LSO60_10885	COG2962	Rard protein
LSO60_10890	COG3040	lipid binding
LSO60_10895	COG0556	nucleotide-excision repair
LSO60_10905	COG2199	diguanylate cyclase activity
LSO60_10910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LSO60_10920	COG0436	Aminotransferase
LSO60_10940	COG1802	Transcriptional regulator
LSO60_10955	COG0174	glutamine synthetase
LSO60_11000	COG1802	Transcriptional regulator
LSO60_11020	COG1522	sequence-specific DNA binding
LSO60_11070	COG0612	Peptidase, M16
LSO60_11075	COG0038	chloride channel
LSO60_11085	COG1823	symporter activity
LSO60_11105	COG2351	hydroxyisourate hydrolase activity
LSO60_11125	COG4172	Belongs to the ABC transporter superfamily
LSO60_11130	COG4239	(ABC) transporter, permease
LSO60_11135	COG4174	ABC transporter (Permease)
LSO60_11140	COG4166	transmembrane transport
LSO60_11145	COG0741	lytic transglycosylase activity
LSO60_11145	COG1388	LysM domain
LSO60_11145	COG1388	LysM domain
LSO60_11145	COG0741	lytic transglycosylase activity
LSO60_11150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LSO60_11175	COG0792	nuclease activity
LSO60_11180	COG3107	peptidoglycan biosynthetic process
LSO60_11195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO60_11200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO60_11205	COG0006	proline dipeptidase activity
LSO60_11210	COG3079	Belongs to the UPF0149 family
LSO60_11235	COG2072	flavoprotein involved in K transport
LSO60_11245	COG0596	Alpha beta hydrolase
LSO60_11250	COG4977	sequence-specific DNA binding
LSO60_11250	COG1917	Cupin 2, conserved barrel domain protein
LSO60_11320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO60_11320	COG0723	plastoquinol--plastocyanin reductase activity
LSO60_11325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO60_11335	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_11350	COG0583	DNA-binding transcription factor activity
LSO60_11360	COG2072	flavoprotein involved in K transport
LSO60_11375	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_11395	COG2217	Heavy metal translocating P-type atpase
LSO60_11420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LSO60_11425	COG2267	carboxylic ester hydrolase activity
LSO60_11430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LSO60_11445	COG1113	amino acid transport
LSO60_11465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSO60_11470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LSO60_11475	COG2072	flavoprotein involved in K transport
LSO60_11490	COG1309	transcriptional regulator
LSO60_11500	COG2814	Major facilitator Superfamily
LSO60_11505	COG1024	Enoyl-CoA hydratase
LSO60_11510	COG1012	belongs to the aldehyde dehydrogenase family
LSO60_11520	COG1960	acyl-CoA dehydrogenase activity
LSO60_11535	COG1629	transport
LSO60_11545	COG1595	DNA-templated transcription, initiation
LSO60_11560	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_11565	COG2610	gluconate transmembrane transporter activity
LSO60_11570	COG0583	DNA-binding transcription factor activity
LSO60_11585	COG2031	fatty acid transporter
LSO60_11590	COG0183	Belongs to the thiolase family
LSO60_11595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LSO60_11600	COG4149	molybdate abc transporter
LSO60_11605	COG0725	ABC transporter, periplasmic molybdate-binding protein
LSO60_11620	COG0477	Major facilitator Superfamily
LSO60_11625	COG0583	DNA-binding transcription factor activity
LSO60_11630	COG1960	acyl-CoA dehydrogenase activity
LSO60_11635	COG2301	Belongs to the HpcH HpaI aldolase family
LSO60_11640	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LSO60_11665	COG0596	Alpha beta hydrolase
LSO60_11670	COG0583	DNA-binding transcription factor activity
LSO60_11685	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSO60_11685	COG1902	pentaerythritol trinitrate reductase activity
LSO60_11690	COG0697	spore germination
LSO60_11695	COG0583	DNA-binding transcription factor activity
LSO60_11720	COG0628	permease
LSO60_11725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LSO60_11730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LSO60_11740	COG0582	viral genome integration into host DNA
LSO60_11750	COG1401	restriction endodeoxyribonuclease activity
LSO60_11770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LSO60_11820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSO60_11910	COG0717	Belongs to the dCTP deaminase family
LSO60_11925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LSO60_11930	COG0489	protein tyrosine kinase activity
LSO60_11940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSO60_11940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSO60_11950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSO60_11985	COG1280	lysine exporter protein (LysE YggA)
LSO60_11990	COG2226	methyltransferase
LSO60_12010	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LSO60_12015	COG2081	HI0933 family
LSO60_12025	COG0668	transmembrane transport
LSO60_12045	COG0583	DNA-binding transcription factor activity
LSO60_12055	COG4773	Receptor
LSO60_12060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LSO60_12070	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO60_12075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LSO60_12080	COG0713	ATP synthesis coupled electron transport
LSO60_12090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO60_12105	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LSO60_12115	COG0649	NAD binding
LSO60_12115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO60_12120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO60_12125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO60_12135	COG2205	protein histidine kinase activity
LSO60_12140	COG0745	RESPONSE REGULATOR receiver
LSO60_12145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LSO60_12145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LSO60_12155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LSO60_12170	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_12235	COG0010	Belongs to the arginase family
LSO60_12265	COG2188	Transcriptional regulator
LSO60_12285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LSO60_12310	COG2132	Multicopper oxidase
LSO60_12325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LSO60_12340	COG4269	membrane
LSO60_12355	COG0742	ribosomal rna small subunit methyltransferase
LSO60_12360	COG1968	undecaprenyl-diphosphatase activity
LSO60_12365	COG1214	PFAM Peptidase M22, glycoprotease
LSO60_12370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LSO60_12420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LSO60_12425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LSO60_12435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LSO60_12440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LSO60_12500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LSO60_12505	COG1846	Transcriptional regulator
LSO60_12545	COG0037	tRNA processing
LSO60_12555	COG0248	Ppx GppA phosphatase
LSO60_12575	COG0776	regulation of translation
LSO60_12580	COG0072	phenylalanine-tRNA ligase activity
LSO60_12585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LSO60_12610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LSO60_12625	COG1238	metal cluster binding
LSO60_12630	COG0625	glutathione transferase activity
LSO60_12640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LSO60_12645	COG0318	PFAM AMP-dependent synthetase and ligase
LSO60_12650	COG3028	Belongs to the UPF0307 family
LSO60_12655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSO60_12660	COG1660	Displays ATPase and GTPase activities
LSO60_12665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LSO60_12675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LSO60_12680	COG0617	tRNA 3'-terminal CCA addition
LSO60_12685	COG1555	photosystem II stabilization
LSO60_12690	COG3956	TIGRFAM MazG family protein
LSO60_12700	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LSO60_12705	COG2315	Protein conserved in bacteria
LSO60_12710	COG0745	RESPONSE REGULATOR receiver
LSO60_12715	COG2205	protein histidine kinase activity
LSO60_12725	COG1960	acyl-CoA dehydrogenase activity
LSO60_12730	COG1960	acyl-CoA dehydrogenase activity
LSO60_12780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LSO60_12795	COG1442	glycosyl transferase family 8
LSO60_12810	COG0438	transferase activity, transferring glycosyl groups
LSO60_12820	COG0438	transferase activity, transferring glycosyl groups
LSO60_12825	COG0726	polysaccharide deacetylase
LSO60_12840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LSO60_12845	COG2205	protein histidine kinase activity
LSO60_12850	COG3706	GGDEF domain
LSO60_12880	COG0697	spore germination
LSO60_12885	COG0789	Transcriptional regulator
LSO60_12895	COG2814	Major facilitator Superfamily
LSO60_12905	COG1230	cation diffusion facilitator family transporter
LSO60_12970	COG4453	Protein conserved in bacteria
LSO60_12975	COG0582	viral genome integration into host DNA
LSO60_12985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LSO60_12995	COG1704	LemA family
LSO60_13005	COG1862	Preprotein translocase
LSO60_13035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LSO60_13040	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_13060	COG0644	oxidoreductase
LSO60_13080	COG2986	histidine ammonia-lyase
LSO60_13095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LSO60_13105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LSO60_13140	COG0124	histidyl-tRNA synthetase
LSO60_13150	COG1426	Protein conserved in bacteria
LSO60_13165	COG0105	UTP biosynthetic process
LSO60_13185	COG0793	Belongs to the peptidase S41A family
LSO60_13200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO60_13205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LSO60_13210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LSO60_13215	COG0280	phosphate acetyltransferase
LSO60_13215	COG0857	belongs to the CobB CobQ family
LSO60_13220	COG1335	isochorismatase
LSO60_13230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LSO60_13230	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LSO60_13235	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LSO60_13240	COG1162	GTPase activity
LSO60_13250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LSO60_13260	COG3783	Cytochrome b(562)
LSO60_13265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LSO60_13270	COG2003	Belongs to the UPF0758 family
LSO60_13275	COG3781	membrane
LSO60_13280	COG0667	Aldo Keto reductase
LSO60_13285	COG0583	DNA-binding transcription factor activity
LSO60_13300	COG2350	Protein conserved in bacteria
LSO60_13315	COG0560	Phosphoserine phosphatase
LSO60_13325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LSO60_13335	COG1530	ribonuclease E activity
LSO60_13340	COG0424	maF-like protein
LSO60_13350	COG1792	Involved in formation and maintenance of cell shape
LSO60_13355	COG1077	Cell shape determining protein MreB Mrl
LSO60_13360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LSO60_13365	COG0154	amidase activity
LSO60_13370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LSO60_13425	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LSO60_13460	COG1902	pentaerythritol trinitrate reductase activity
LSO60_13465	COG4772	TonB-dependent receptor
LSO60_13470	COG2094	Belongs to the DNA glycosylase MPG family
LSO60_13475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LSO60_13480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSO60_13495	COG1217	gtp-binding protein TYPA
LSO60_13500	COG2233	PERMEase
LSO60_13505	COG2813	Specifically methylates the guanine in position
LSO60_13510	COG0833	amino acid
LSO60_13515	COG1690	Belongs to the RtcB family
LSO60_13530	COG2198	Histidine kinase
LSO60_13530	COG0643	Histidine kinase
LSO60_13535	COG0840	transmembrane signaling receptor activity
LSO60_13570	COG0442	prolyl-tRNA aminoacylation
LSO60_13580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO60_13600	COG2207	Transcriptional regulator
LSO60_13615	COG0183	Belongs to the thiolase family
LSO60_13630	COG4667	esterase of the alpha-beta hydrolase superfamily
LSO60_13640	COG2153	protein acetylation
LSO60_13650	COG1272	protein, Hemolysin III
LSO60_13655	COG0477	Major facilitator Superfamily
LSO60_13660	COG1408	metallophosphoesterase
LSO60_13665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LSO60_13680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LSO60_13700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LSO60_13705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LSO60_13710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LSO60_13720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LSO60_13725	COG0625	glutathione transferase activity
LSO60_13730	COG2969	positive regulation of protein catabolic process
LSO60_13790	COG2199	diguanylate cyclase activity
LSO60_13795	COG2885	chlorophyll binding
LSO60_13820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LSO60_13825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LSO60_13835	COG0653	protein targeting
LSO60_13840	COG0450	alkyl hydroperoxide reductase
LSO60_13860	COG0285	dihydrofolate synthase activity
LSO60_13865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LSO60_13905	COG4206	TonB-dependent receptor
LSO60_13910	COG2096	Adenosyltransferase
LSO60_13930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSO60_13950	COG0784	Response regulator, receiver
LSO60_13950	COG2205	protein histidine kinase activity
LSO60_13950	COG5002	protein histidine kinase activity
LSO60_13960	COG2084	Dehydrogenase
LSO60_13965	COG3622	Belongs to the hyi family
LSO60_13995	COG0740	serine-type endopeptidase activity
LSO60_14000	COG0544	peptidyl-prolyl cis-trans isomerase activity
LSO60_14005	COG4774	siderophore transport
LSO60_14010	COG3128	pkhd-type hydroxylase
LSO60_14015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSO60_14020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO60_14025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO60_14025	COG2813	Specifically methylates the guanine in position
LSO60_14035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LSO60_14070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LSO60_14085	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LSO60_14125	COG0788	formyltetrahydrofolate deformylase activity
LSO60_14150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LSO60_14150	COG4651	solute:proton antiporter activity
LSO60_14170	COG0210	DNA helicase
LSO60_14180	COG5001	Diguanylate cyclase
LSO60_14180	COG4251	negative regulation of phosphorylation
LSO60_14180	COG3706	GGDEF domain
LSO60_14180	COG2203	Gaf domain
LSO60_14210	COG2900	Belongs to the SlyX family
LSO60_14215	COG0488	(ABC) transporter
LSO60_14225	COG1560	Kdo2-lipid A biosynthetic process
LSO60_14230	COG0438	transferase activity, transferring glycosyl groups
LSO60_14235	COG1301	dicarboxylic acid transport
LSO60_14270	COG0101	tRNA pseudouridine synthase activity
LSO60_14285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LSO60_14295	COG0473	3-isopropylmalate dehydrogenase activity
LSO60_14310	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LSO60_14320	COG0583	DNA-binding transcription factor activity
LSO60_14335	COG0494	nUDIX hydrolase
LSO60_14345	COG1960	acyl-CoA dehydrogenase activity
LSO60_14355	COG0753	catalase activity
LSO60_14360	COG4993	Dehydrogenase
LSO60_14375	COG0583	DNA-binding transcription factor activity
LSO60_14395	COG1530	ribonuclease E activity
LSO60_14400	COG0318	PFAM AMP-dependent synthetase and ligase
LSO60_14415	COG0450	alkyl hydroperoxide reductase
LSO60_14420	COG0583	DNA-binding transcription factor activity
LSO60_14425	COG4221	oxidoreductase activity
LSO60_14435	COG1595	DNA-templated transcription, initiation
LSO60_14445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LSO60_14455	COG0534	Mate efflux family protein
LSO60_14470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LSO60_14475	COG0254	rRNA binding
LSO60_14485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO60_14515	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LSO60_14525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSO60_14530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LSO60_14540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LSO60_14550	COG0644	oxidoreductase
LSO60_14550	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LSO60_14565	COG0425	Belongs to the sulfur carrier protein TusA family
LSO60_14570	COG4535	Mg2 and Co2 transporter CorC
LSO60_14575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LSO60_14580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSO60_14600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LSO60_14610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LSO60_14615	COG0484	heat shock protein binding
LSO60_14630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LSO60_14635	COG0598	Magnesium transport protein CorA
LSO60_14640	COG2841	Protein conserved in bacteria
LSO60_14645	COG1185	polyribonucleotide nucleotidyltransferase activity
LSO60_14650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LSO60_14655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LSO60_14660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSO60_14665	COG1074	ATP-dependent DNA helicase activity
LSO60_14670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LSO60_14695	COG2226	methyltransferase
LSO60_14715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LSO60_14730	COG2111	Na H antiporter
LSO60_14730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LSO60_14735	COG1006	Multisubunit Na H antiporter MnhC subunit
LSO60_14740	COG0651	ATP synthesis coupled electron transport
LSO60_14745	COG1863	multisubunit Na H antiporter MnhE subunit
LSO60_14750	COG2212	antiporter activity
LSO60_14755	COG1320	monovalent cation:proton antiporter activity
LSO60_14770	COG0195	Participates in both transcription termination and antitermination
LSO60_14775	COG0779	Required for maturation of 30S ribosomal subunits
LSO60_14800	COG0149	triose-phosphate isomerase activity
LSO60_14820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LSO60_14825	COG0237	dephospho-CoA kinase activity
LSO60_14835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LSO60_14840	COG3123	guanosine phosphorylase activity
LSO60_14845	COG0497	DNA recombination
LSO60_14850	COG1678	Uncharacterized ACR, COG1678
LSO60_14855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LSO60_14870	COG1289	transmembrane transporter activity
LSO60_14880	COG1132	(ABC) transporter
LSO60_14890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LSO60_14890	COG2169	Transcriptional regulator
LSO60_14895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LSO60_14920	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSO60_14920	COG1024	Enoyl-CoA hydratase
LSO60_14940	COG3307	-O-antigen
LSO60_14950	COG3307	-O-antigen
LSO60_14955	COG4969	Belongs to the N-Me-Phe pilin family
LSO60_14965	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LSO60_14970	COG1704	LemA family
LSO60_14980	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_14990	COG0493	'glutamate synthase
LSO60_14995	COG0067	glutamate synthase
LSO60_14995	COG0069	glutamate synthase activity
LSO60_14995	COG0070	glutamate synthase
LSO60_15005	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LSO60_15010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LSO60_15045	COG2226	methyltransferase
LSO60_15050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LSO60_15055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LSO60_15060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LSO60_15075	COG0275	rRNA processing
LSO60_15090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LSO60_15140	COG0488	(ABC) transporter
LSO60_15145	COG0028	Belongs to the TPP enzyme family
LSO60_15155	COG4221	oxidoreductase activity
LSO60_15185	COG0427	acetyl-CoA hydrolase
LSO60_15190	COG0456	acetyltransferase
LSO60_15220	COG0131	Imidazoleglycerol-phosphate dehydratase
LSO60_15225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LSO60_15235	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LSO60_15240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LSO60_15250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO60_15255	COG0531	amino acid
LSO60_15275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LSO60_15310	COG3158	transport of potassium into the cell
LSO60_15365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO60_15375	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSO60_15390	COG2814	Major facilitator Superfamily
LSO60_15400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LSO60_15445	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LSO60_15455	COG1335	isochorismatase
LSO60_15490	COG1538	Outer membrane efflux protein
LSO60_15525	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_15535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LSO60_15540	COG1113	amino acid transport
LSO60_15545	COG0251	oxidation-reduction process
LSO60_15555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO60_15565	COG1448	Aminotransferase
LSO60_15575	COG0277	FAD linked oxidase domain protein
LSO60_15580	COG1304	FMN binding
LSO60_15585	COG2186	Transcriptional regulator
LSO60_15590	COG1620	l-lactate permease
LSO60_15595	COG0583	DNA-binding transcription factor activity
LSO60_15600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LSO60_15615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LSO60_15630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LSO60_15635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LSO60_15640	COG1216	Glycosyl transferase, family 2
LSO60_15650	COG1215	transferase activity, transferring glycosyl groups
LSO60_15660	COG0438	transferase activity, transferring glycosyl groups
LSO60_15660	COG0297	glycogen (starch) synthase activity
LSO60_15670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LSO60_15675	COG1596	polysaccharide export
LSO60_15705	COG3023	N-Acetylmuramoyl-L-alanine amidase
LSO60_15725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LSO60_15755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LSO60_15760	COG0546	phosphoglycolate phosphatase activity
LSO60_15765	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_15795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LSO60_15795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LSO60_15800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO60_15805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO60_15810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO60_15815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO60_15820	COG1116	anion transmembrane transporter activity
LSO60_15830	COG2233	PERMEase
LSO60_15835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO60_15840	COG0251	oxidation-reduction process
LSO60_15845	COG1335	isochorismatase
LSO60_15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO60_15855	COG1309	transcriptional regulator
LSO60_15860	COG0596	Alpha beta hydrolase
LSO60_15875	COG0196	riboflavin kinase activity
LSO60_15880	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LSO60_15885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LSO60_15890	COG1047	Peptidyl-prolyl cis-trans
LSO60_15910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LSO60_15910	COG2885	chlorophyll binding
LSO60_16040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LSO60_16045	COG0657	acetylesterase activity
LSO60_16065	COG0583	DNA-binding transcription factor activity
LSO60_16070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LSO60_16075	COG0443	Heat shock 70 kDa protein
LSO60_16090	COG2951	lytic endotransglycosylase activity
LSO60_16095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LSO60_16110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LSO60_16135	COG0861	Integral membrane protein TerC family
LSO60_16145	COG0402	S-adenosylhomocysteine deaminase activity
LSO60_16160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LSO60_16165	COG3293	Transposase
LSO60_16175	COG0706	membrane insertase activity
LSO60_16180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LSO60_16185	COG0594	ribonuclease P activity
LSO60_16410	COG1192	Involved in chromosome partitioning
LSO60_16415	COG1475	DNA binding
LSO60_16590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LSO60_16715	COG4372	Transposase
LSO60_16795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSO60_16890	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_16900	COG2826	transposase and inactivated derivatives, IS30 family
LSO60_17040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LSO60_17090	COG1525	nuclease
LSO60_17100	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LSO60_17105	COG3421	Type III restriction
LSO60_17150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LSO60_17310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LSO60_17320	COG4372	Transposase
LSO60_17365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSO60_17375	COG3657	addiction module killer protein
LSO60_17380	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSO60_17385	COG2801	Transposase and inactivated derivatives
LSO60_17395	COG0659	secondary active sulfate transmembrane transporter activity
LSO60_17405	COG3657	addiction module killer protein
LSO60_17410	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSO60_17440	COG0488	(ABC) transporter
LSO60_17445	COG3173	Aminoglycoside phosphotransferase
LSO60_17460	COG2205	protein histidine kinase activity
LSO60_17465	COG0745	RESPONSE REGULATOR receiver
LSO60_17475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO60_17480	COG1538	Outer membrane efflux protein
LSO60_17490	COG5002	protein histidine kinase activity
LSO60_17525	COG5002	protein histidine kinase activity
LSO60_17665	COG2801	Transposase and inactivated derivatives
LSO60_17700	COG1660	Displays ATPase and GTPase activities
LSO60_17765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSO60_17770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSO60_17790	COG2369	cell adhesion
LSO60_17795	COG0582	viral genome integration into host DNA
LSO60_17860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO60_17885	COG2132	Multicopper oxidase
LSO60_17900	COG2205	protein histidine kinase activity
LSO60_17905	COG3174	membrane
LSO60_17910	COG2217	Heavy metal translocating P-type atpase
LSO60_17940	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LSO60_17980	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSO60_18010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LSO60_18015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LSO60_18020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LSO60_18025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LSO60_18085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LSO60_18115	COG0583	DNA-binding transcription factor activity
LSO60_18125	COG2233	PERMEase
LSO60_18145	COG0583	DNA-binding transcription factor activity
LSO60_18230	COG2184	nucleotidyltransferase activity
LSO60_18255	COG3550	peptidyl-serine autophosphorylation
LSO60_18275	COG3335	DDE superfamily endonuclease
LSO60_18310	COG1570	exodeoxyribonuclease VII activity
LSO60_18325	COG1877	trehalose-phosphatase activity
LSO60_18330	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LSO60_18335	COG2223	nitrite transmembrane transporter activity
LSO60_18380	COG2323	membrane
LSO60_18430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSO60_18435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSO60_18490	COG0804	urea catabolic process
LSO60_18500	COG0831	urea catabolic process
LSO60_18505	COG0829	nickel cation binding
LSO60_18520	COG0830	nickel cation binding
LSO60_18555	COG1475	DNA binding
LSO60_18560	COG1192	Involved in chromosome partitioning
LSO60_18605	COG1028	Short-chain dehydrogenase reductase Sdr
LSO60_18610	COG0583	DNA-binding transcription factor activity
LSO60_18620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSO60_18635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LSO60_18675	COG1063	alcohol dehydrogenase
LSO60_18690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSO60_18760	COG4372	Transposase
LSO60_18810	COG4227	nucleotidyltransferase activity
LSO60_18835	COG1192	Involved in chromosome partitioning
LSO60_18865	COG3504	Conjugal transfer protein
LSO60_18890	COG0739	heme binding
LSO60_18890	COG1196	nuclear chromosome segregation
LSO60_18890	COG0741	lytic transglycosylase activity
LSO60_18905	COG1196	nuclear chromosome segregation
LSO60_18905	COG0741	lytic transglycosylase activity
LSO60_18905	COG0739	heme binding
LSO60_18910	COG3293	Transposase
LSO60_18935	COG3293	Transposase
LSO60_18945	COG3451	type IV secretory pathway VirB4
LSO60_19055	COG1487	ribonuclease activity