locus-tag	class	description
LSO58_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LSO58_00010	COG0592	DNA-directed DNA polymerase activity
LSO58_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LSO58_00020	COG0187	DNA topoisomerase II activity
LSO58_00030	COG0488	(ABC) transporter
LSO58_00050	COG0316	Belongs to the HesB IscA family
LSO58_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LSO58_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LSO58_00090	COG0693	protein deglycase activity
LSO58_00105	COG1012	belongs to the aldehyde dehydrogenase family
LSO58_00110	COG0733	neurotransmitter:sodium symporter activity
LSO58_00120	COG0428	transporter
LSO58_00125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LSO58_00130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LSO58_00145	COG1252	NADH dehydrogenase
LSO58_00150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LSO58_00165	COG2233	PERMEase
LSO58_00170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LSO58_00175	COG1309	transcriptional regulator
LSO58_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO58_00195	COG0484	heat shock protein binding
LSO58_00200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LSO58_00210	COG2814	Major facilitator Superfamily
LSO58_00215	COG0583	DNA-binding transcription factor activity
LSO58_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO58_00230	COG1064	alcohol dehydrogenase
LSO58_00235	COG2818	Glycosylase
LSO58_00250	COG1194	a g-specific adenine glycosylase
LSO58_00260	COG0412	Dienelactone hydrolase
LSO58_00265	COG5487	UPF0391 membrane protein
LSO58_00270	COG2983	Belongs to the UPF0260 family
LSO58_00285	COG2133	pyrroloquinoline quinone binding
LSO58_00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LSO58_00300	COG2116	formate transmembrane transporter activity
LSO58_00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LSO58_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LSO58_00320	COG1335	isochorismatase
LSO58_00325	COG0385	Bile acid
LSO58_00330	COG2388	GCN5-related N-acetyl-transferase
LSO58_00350	COG3188	usher protein
LSO58_00360	COG3121	Chaperone
LSO58_00375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LSO58_00385	COG1061	Type III restriction enzyme res subunit
LSO58_00390	COG1002	Type II restriction enzyme, methylase subunits
LSO58_00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LSO58_00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LSO58_00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LSO58_00455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LSO58_00460	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LSO58_00475	COG0560	Phosphoserine phosphatase
LSO58_00475	COG3830	Belongs to the UPF0237 family
LSO58_00495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LSO58_00505	COG0688	phosphatidylethanolamine metabolic process
LSO58_00515	COG0300	oxidoreductase activity
LSO58_00545	COG0534	Mate efflux family protein
LSO58_00550	COG0436	Aminotransferase
LSO58_00555	COG2733	membrane
LSO58_00570	COG2918	glutathione biosynthetic process
LSO58_00575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LSO58_00585	COG3150	esterase
LSO58_00605	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LSO58_00610	COG4266	Belongs to the allantoicase family
LSO58_00615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO58_00625	COG1247	-acetyltransferase
LSO58_00670	COG0625	glutathione transferase activity
LSO58_00675	COG3706	GGDEF domain
LSO58_00690	COG1393	Belongs to the ArsC family
LSO58_00695	COG0708	Exodeoxyribonuclease III
LSO58_00715	COG0189	ligase activity
LSO58_00720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LSO58_00730	COG1181	Belongs to the D-alanine--D-alanine ligase family
LSO58_00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LSO58_00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LSO58_00780	COG2119	membrane
LSO58_00785	COG0426	domain, Protein
LSO58_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO58_00805	COG0259	pyridoxamine-phosphate oxidase activity
LSO58_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LSO58_00815	COG1476	TRANSCRIPTIONal
LSO58_00840	COG1902	pentaerythritol trinitrate reductase activity
LSO58_00850	COG1519	Transferase
LSO58_00860	COG0668	transmembrane transport
LSO58_00870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSO58_00900	COG0004	ammonium transporteR
LSO58_00915	COG0784	Response regulator, receiver
LSO58_00915	COG2205	protein histidine kinase activity
LSO58_00920	COG3162	membrane
LSO58_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSO58_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LSO58_00960	COG2801	Transposase and inactivated derivatives
LSO58_00965	COG1733	regulation of RNA biosynthetic process
LSO58_00975	COG2249	NAD(P)H dehydrogenase (quinone) activity
LSO58_00990	COG4628	conserved protein (DUF2132)
LSO58_01015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LSO58_01020	COG3550	peptidyl-serine autophosphorylation
LSO58_01065	COG1538	Outer membrane efflux protein
LSO58_01070	COG1132	(ABC) transporter
LSO58_01095	COG0753	catalase activity
LSO58_01110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO58_01120	COG3756	Protein conserved in bacteria
LSO58_01165	COG1192	Involved in chromosome partitioning
LSO58_01180	COG0586	Pfam SNARE associated Golgi protein
LSO58_01185	COG2259	Doxx family
LSO58_01190	COG3111	PFAM Bacterial OB fold (BOF) protein
LSO58_01195	COG0519	Catalyzes the synthesis of GMP from XMP
LSO58_01195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LSO58_01255	COG0281	malic enzyme
LSO58_01265	COG1388	LysM domain
LSO58_01265	COG0791	NLP P60 protein
LSO58_01275	COG1280	lysine exporter protein (LysE YggA)
LSO58_01280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LSO58_01285	COG1121	(ABC) transporter
LSO58_01305	COG0356	it plays a direct role in the translocation of protons across the membrane
LSO58_01335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LSO58_01340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LSO58_01365	COG0386	Belongs to the glutathione peroxidase family
LSO58_01375	COG2814	Major facilitator Superfamily
LSO58_01380	COG1309	transcriptional regulator
LSO58_01385	COG0697	spore germination
LSO58_01425	COG3845	ABC transporter
LSO58_01430	COG4603	Belongs to the binding-protein-dependent transport system permease family
LSO58_01435	COG1079	Belongs to the binding-protein-dependent transport system permease family
LSO58_01440	COG0009	L-threonylcarbamoyladenylate synthase
LSO58_01445	COG0758	DNA mediated transformation
LSO58_01450	COG1652	LysM domain
LSO58_01480	COG1309	transcriptional regulator
LSO58_01530	COG0477	Major facilitator Superfamily
LSO58_01535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSO58_01555	COG1253	flavin adenine dinucleotide binding
LSO58_01565	COG2860	membrane
LSO58_01575	COG0477	Major facilitator Superfamily
LSO58_01585	COG0318	PFAM AMP-dependent synthetase and ligase
LSO58_01600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LSO58_01625	COG0347	Belongs to the P(II) protein family
LSO58_01630	COG0004	ammonium transporteR
LSO58_01640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSO58_01640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LSO58_01675	COG0795	lipopolysaccharide-transporting ATPase activity
LSO58_01680	COG0795	lipopolysaccharide-transporting ATPase activity
LSO58_01685	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LSO58_01690	COG0793	Belongs to the peptidase S41A family
LSO58_01705	COG2197	response regulator
LSO58_01715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LSO58_01725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LSO58_01730	COG4974	Belongs to the 'phage' integrase family
LSO58_01750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LSO58_01755	COG0772	Belongs to the SEDS family
LSO58_01760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LSO58_01765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LSO58_01770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LSO58_01775	COG0494	nUDIX hydrolase
LSO58_01805	COG3275	phosphorelay sensor kinase activity
LSO58_01815	COG0181	hydroxymethylbilane synthase activity
LSO58_01860	COG1716	ATPase activity
LSO58_01895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LSO58_01915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LSO58_01920	COG0081	regulation of translation
LSO58_01935	COG0085	RNA polymerase activity
LSO58_01940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LSO58_01975	COG0326	Molecular chaperone. Has ATPase activity
LSO58_02005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LSO58_02030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSO58_02035	COG1758	RNA polymerase activity
LSO58_02040	COG0194	GDP metabolic process
LSO58_02085	COG0228	four-way junction DNA binding
LSO58_02090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LSO58_02100	COG0335	large ribosomal subunit rRNA binding
LSO58_02105	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LSO58_02110	COG5380	lipid catabolic process
LSO58_02115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LSO58_02135	COG5006	permease, DMT superfamily
LSO58_02140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSO58_02145	COG0277	FAD linked oxidase domain protein
LSO58_02165	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LSO58_02170	COG2249	NAD(P)H dehydrogenase (quinone) activity
LSO58_02185	COG0628	permease
LSO58_02190	COG1192	Involved in chromosome partitioning
LSO58_02235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LSO58_02250	COG0583	DNA-binding transcription factor activity
LSO58_02270	COG0752	glycyl-tRNA synthetase alpha subunit
LSO58_02285	COG0517	IMP dehydrogenase activity
LSO58_02290	COG1983	PspC domain protein
LSO58_02300	COG1960	acyl-CoA dehydrogenase activity
LSO58_02315	COG2885	chlorophyll binding
LSO58_02325	COG0408	coproporphyrinogen oxidase activity
LSO58_02330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LSO58_02335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LSO58_02355	COG0513	Belongs to the DEAD box helicase family
LSO58_02365	COG1127	ABC transporter
LSO58_02370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LSO58_02390	COG0598	Magnesium transport protein CorA
LSO58_02400	COG0494	nUDIX hydrolase
LSO58_02405	COG1040	competence protein
LSO58_02410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LSO58_02425	COG2937	Belongs to the GPAT DAPAT family
LSO58_02430	COG1946	Acyl-CoA thioesterase
LSO58_02435	COG1301	dicarboxylic acid transport
LSO58_02450	COG1959	2 iron, 2 sulfur cluster binding
LSO58_02455	COG1017	nitric oxide dioxygenase activity
LSO58_02455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LSO58_02460	COG0433	COG0433 Predicted ATPase
LSO58_02475	COG0051	transcription antitermination factor activity, RNA binding
LSO58_02480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LSO58_02485	COG0088	Forms part of the polypeptide exit tunnel
LSO58_02500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LSO58_02505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LSO58_02515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LSO58_02525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LSO58_02530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LSO58_02535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LSO58_02540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LSO58_02550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LSO58_02555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LSO58_02565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LSO58_02590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LSO58_02600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LSO58_02605	COG0202	RNA polymerase activity
LSO58_02610	COG0203	ribosomal protein L17
LSO58_02615	COG2072	flavoprotein involved in K transport
LSO58_02620	COG1960	acyl-CoA dehydrogenase activity
LSO58_02625	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LSO58_02655	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LSO58_02660	COG0339	signal peptide processing
LSO58_02670	COG0557	exoribonuclease II activity
LSO58_02715	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSO58_02725	COG2814	Major facilitator Superfamily
LSO58_02730	COG0583	DNA-binding transcription factor activity
LSO58_02745	COG1295	ribonuclease BN
LSO58_02780	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LSO58_02785	COG1702	phosphate starvation-inducible protein PhoH
LSO58_02790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LSO58_02795	COG0741	lytic transglycosylase activity
LSO58_02795	COG0739	heme binding
LSO58_02795	COG1196	nuclear chromosome segregation
LSO58_02805	COG0039	L-malate dehydrogenase activity
LSO58_02825	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LSO58_02830	COG1183	phosphatidylcholine synthase activity
LSO58_02890	COG2969	positive regulation of protein catabolic process
LSO58_02895	COG0625	glutathione transferase activity
LSO58_02900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LSO58_02910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LSO58_02915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LSO58_02920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LSO58_02940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LSO58_02955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LSO58_02960	COG1408	metallophosphoesterase
LSO58_02965	COG0477	Major facilitator Superfamily
LSO58_02970	COG1272	protein, Hemolysin III
LSO58_02980	COG2153	protein acetylation
LSO58_02990	COG4667	esterase of the alpha-beta hydrolase superfamily
LSO58_03005	COG0183	Belongs to the thiolase family
LSO58_03020	COG2207	Transcriptional regulator
LSO58_03040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO58_03050	COG0442	prolyl-tRNA aminoacylation
LSO58_03085	COG0840	transmembrane signaling receptor activity
LSO58_03090	COG2198	Histidine kinase
LSO58_03090	COG0643	Histidine kinase
LSO58_03105	COG1690	Belongs to the RtcB family
LSO58_03110	COG0833	amino acid
LSO58_03115	COG2813	Specifically methylates the guanine in position
LSO58_03120	COG2233	PERMEase
LSO58_03125	COG1217	gtp-binding protein TYPA
LSO58_03140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSO58_03145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LSO58_03150	COG2094	Belongs to the DNA glycosylase MPG family
LSO58_03155	COG4772	TonB-dependent receptor
LSO58_03160	COG1902	pentaerythritol trinitrate reductase activity
LSO58_03195	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LSO58_03250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LSO58_03255	COG0154	amidase activity
LSO58_03260	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LSO58_03265	COG1077	Cell shape determining protein MreB Mrl
LSO58_03270	COG1792	Involved in formation and maintenance of cell shape
LSO58_03280	COG0424	maF-like protein
LSO58_03285	COG1530	ribonuclease E activity
LSO58_03295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LSO58_03305	COG0560	Phosphoserine phosphatase
LSO58_03320	COG2350	Protein conserved in bacteria
LSO58_03335	COG0583	DNA-binding transcription factor activity
LSO58_03340	COG0667	Aldo Keto reductase
LSO58_03345	COG3781	membrane
LSO58_03350	COG2003	Belongs to the UPF0758 family
LSO58_03355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LSO58_03360	COG3783	Cytochrome b(562)
LSO58_03370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LSO58_03380	COG1162	GTPase activity
LSO58_03385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LSO58_03395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LSO58_03395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LSO58_03405	COG1335	isochorismatase
LSO58_03410	COG0280	phosphate acetyltransferase
LSO58_03410	COG0857	belongs to the CobB CobQ family
LSO58_03415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LSO58_03420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LSO58_03425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO58_03440	COG0793	Belongs to the peptidase S41A family
LSO58_03460	COG0105	UTP biosynthetic process
LSO58_03485	COG0124	histidyl-tRNA synthetase
LSO58_03520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LSO58_03530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LSO58_03545	COG2986	histidine ammonia-lyase
LSO58_03565	COG0644	oxidoreductase
LSO58_03585	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_03590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LSO58_03620	COG1862	Preprotein translocase
LSO58_03630	COG1704	LemA family
LSO58_03640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LSO58_03740	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LSO58_03750	COG0732	type I restriction modification DNA specificity domain
LSO58_03765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LSO58_03790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LSO58_03805	COG0745	RESPONSE REGULATOR receiver
LSO58_03815	COG4774	siderophore transport
LSO58_03830	COG1230	cation diffusion facilitator family transporter
LSO58_03840	COG2814	Major facilitator Superfamily
LSO58_03850	COG0789	Transcriptional regulator
LSO58_03855	COG0697	spore germination
LSO58_03885	COG3706	GGDEF domain
LSO58_03890	COG2205	protein histidine kinase activity
LSO58_03895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LSO58_03910	COG0726	polysaccharide deacetylase
LSO58_03915	COG0438	transferase activity, transferring glycosyl groups
LSO58_03925	COG0438	transferase activity, transferring glycosyl groups
LSO58_03940	COG1442	glycosyl transferase family 8
LSO58_03955	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LSO58_04005	COG1960	acyl-CoA dehydrogenase activity
LSO58_04010	COG1960	acyl-CoA dehydrogenase activity
LSO58_04020	COG2205	protein histidine kinase activity
LSO58_04025	COG0745	RESPONSE REGULATOR receiver
LSO58_04030	COG2315	Protein conserved in bacteria
LSO58_04050	COG3956	TIGRFAM MazG family protein
LSO58_04055	COG1555	photosystem II stabilization
LSO58_04060	COG0617	tRNA 3'-terminal CCA addition
LSO58_04065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LSO58_04075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LSO58_04080	COG1660	Displays ATPase and GTPase activities
LSO58_04085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LSO58_04090	COG3028	Belongs to the UPF0307 family
LSO58_04095	COG0318	PFAM AMP-dependent synthetase and ligase
LSO58_04100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LSO58_04110	COG0625	glutathione transferase activity
LSO58_04115	COG1238	metal cluster binding
LSO58_04130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LSO58_04155	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LSO58_04160	COG0072	phenylalanine-tRNA ligase activity
LSO58_04165	COG0776	regulation of translation
LSO58_04185	COG0248	Ppx GppA phosphatase
LSO58_04195	COG0037	tRNA processing
LSO58_04235	COG1846	Transcriptional regulator
LSO58_04240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LSO58_04300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LSO58_04305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LSO58_04315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LSO58_04375	COG1214	PFAM Peptidase M22, glycoprotease
LSO58_04380	COG1968	undecaprenyl-diphosphatase activity
LSO58_04385	COG0742	ribosomal rna small subunit methyltransferase
LSO58_04400	COG4269	membrane
LSO58_04415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LSO58_04425	COG2132	Multicopper oxidase
LSO58_04450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LSO58_04485	COG1074	ATP-dependent DNA helicase activity
LSO58_04490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LSO58_04505	COG0745	RESPONSE REGULATOR receiver
LSO58_04510	COG2205	protein histidine kinase activity
LSO58_04520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO58_04525	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO58_04530	COG0649	NAD binding
LSO58_04530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO58_04540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LSO58_04555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO58_04565	COG0713	ATP synthesis coupled electron transport
LSO58_04570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LSO58_04575	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LSO58_04585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LSO58_04600	COG0583	DNA-binding transcription factor activity
LSO58_04620	COG0668	transmembrane transport
LSO58_04630	COG2081	HI0933 family
LSO58_04635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LSO58_04655	COG2226	methyltransferase
LSO58_04660	COG1280	lysine exporter protein (LysE YggA)
LSO58_04695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSO58_04700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSO58_04700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSO58_04710	COG0489	protein tyrosine kinase activity
LSO58_04715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LSO58_04730	COG0717	Belongs to the dCTP deaminase family
LSO58_04770	COG4372	Transposase
LSO58_04785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LSO58_04790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LSO58_04795	COG0628	permease
LSO58_04820	COG0583	DNA-binding transcription factor activity
LSO58_04825	COG0697	spore germination
LSO58_04830	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSO58_04830	COG1902	pentaerythritol trinitrate reductase activity
LSO58_04840	COG0582	viral genome integration into host DNA
LSO58_04945	COG2814	Major facilitator Superfamily
LSO58_04960	COG1230	cation diffusion facilitator family transporter
LSO58_04965	COG2059	Chromate
LSO58_05010	COG0601	transmembrane transport
LSO58_05015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LSO58_05035	COG1132	(ABC) transporter
LSO58_05040	COG1132	(ABC) transporter
LSO58_05060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LSO58_05075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO58_05080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO58_05085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO58_05090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO58_05125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO58_05135	COG0583	DNA-binding transcription factor activity
LSO58_05145	COG0596	Alpha beta hydrolase
LSO58_05165	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LSO58_05170	COG2301	Belongs to the HpcH HpaI aldolase family
LSO58_05175	COG1960	acyl-CoA dehydrogenase activity
LSO58_05180	COG0583	DNA-binding transcription factor activity
LSO58_05185	COG0477	Major facilitator Superfamily
LSO58_05200	COG0725	ABC transporter, periplasmic molybdate-binding protein
LSO58_05205	COG4149	molybdate abc transporter
LSO58_05210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LSO58_05215	COG0183	Belongs to the thiolase family
LSO58_05220	COG2031	fatty acid transporter
LSO58_05240	COG2610	gluconate transmembrane transporter activity
LSO58_05245	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_05260	COG1595	DNA-templated transcription, initiation
LSO58_05270	COG1629	transport
LSO58_05285	COG1960	acyl-CoA dehydrogenase activity
LSO58_05295	COG1012	belongs to the aldehyde dehydrogenase family
LSO58_05300	COG1024	Enoyl-CoA hydratase
LSO58_05305	COG2814	Major facilitator Superfamily
LSO58_05315	COG1309	transcriptional regulator
LSO58_05330	COG2072	flavoprotein involved in K transport
LSO58_05335	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LSO58_05340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSO58_05360	COG1113	amino acid transport
LSO58_05375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LSO58_05385	COG2267	carboxylic ester hydrolase activity
LSO58_05390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LSO58_05415	COG2217	Heavy metal translocating P-type atpase
LSO58_05435	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_05465	COG3079	Belongs to the UPF0149 family
LSO58_05470	COG0006	proline dipeptidase activity
LSO58_05475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO58_05480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO58_05495	COG3107	peptidoglycan biosynthetic process
LSO58_05500	COG0792	nuclease activity
LSO58_05525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LSO58_05530	COG0741	lytic transglycosylase activity
LSO58_05530	COG1388	LysM domain
LSO58_05530	COG0741	lytic transglycosylase activity
LSO58_05530	COG1388	LysM domain
LSO58_05535	COG4166	transmembrane transport
LSO58_05540	COG4174	ABC transporter (Permease)
LSO58_05545	COG4239	(ABC) transporter, permease
LSO58_05550	COG4172	Belongs to the ABC transporter superfamily
LSO58_05570	COG2351	hydroxyisourate hydrolase activity
LSO58_05580	COG1187	pseudouridine synthase activity
LSO58_05590	COG1823	symporter activity
LSO58_05595	COG0384	phenazine biosynthesis protein PhzF
LSO58_05600	COG0038	chloride channel
LSO58_05605	COG0612	Peptidase, M16
LSO58_05660	COG1522	sequence-specific DNA binding
LSO58_05680	COG1802	Transcriptional regulator
LSO58_05715	COG0174	glutamine synthetase
LSO58_05730	COG0436	Aminotransferase
LSO58_05740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LSO58_05745	COG2199	diguanylate cyclase activity
LSO58_05755	COG0556	nucleotide-excision repair
LSO58_05760	COG3040	lipid binding
LSO58_05765	COG2962	Rard protein
LSO58_05790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LSO58_05805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSO58_05815	COG2070	2-Nitropropane dioxygenase
LSO58_05820	COG0531	amino acid
LSO58_05825	COG4303	Ethanolamine ammonia lyase large subunit
LSO58_05830	COG4302	ethanolamine ammonia-lyase activity
LSO58_05835	COG0632	four-way junction helicase activity
LSO58_05860	COG1764	response to oxidative stress
LSO58_05865	COG2985	domain, Protein
LSO58_05875	COG1960	acyl-CoA dehydrogenase activity
LSO58_05895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LSO58_05905	COG2195	Cleaves the N-terminal amino acid of tripeptides
LSO58_05910	COG3022	response to hydroperoxide
LSO58_05955	COG1643	Atp-dependent helicase
LSO58_05965	COG0243	molybdopterin cofactor binding
LSO58_05970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LSO58_05980	COG0833	amino acid
LSO58_05990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LSO58_05995	COG0418	dihydroorotase activity
LSO58_06000	COG2203	Gaf domain
LSO58_06000	COG3706	GGDEF domain
LSO58_06000	COG4251	negative regulation of phosphorylation
LSO58_06000	COG5001	Diguanylate cyclase
LSO58_06020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LSO58_06040	COG0823	Involved in the tonB-independent uptake of proteins
LSO58_06060	COG0824	Thioesterase
LSO58_06065	COG2255	four-way junction helicase activity
LSO58_06080	COG4521	taurine ABC transporter
LSO58_06085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LSO58_06090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO58_06095	COG2175	clavaminate synthase activity
LSO58_06100	COG4993	Dehydrogenase
LSO58_06120	COG2814	Major facilitator Superfamily
LSO58_06125	COG0583	DNA-binding transcription factor activity
LSO58_06130	COG4638	Rieske (2fe-2S)
LSO58_06135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LSO58_06140	COG0543	2 iron, 2 sulfur cluster binding
LSO58_06140	COG0633	Ferredoxin
LSO58_06145	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_06150	COG3135	benzoate transporter
LSO58_06155	COG3485	protocatechuate 3,4-dioxygenase
LSO58_06160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LSO58_06165	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LSO58_06170	COG0583	DNA-binding transcription factor activity
LSO58_06175	COG4948	Mandelate Racemase Muconate Lactonizing
LSO58_06180	COG4829	muconolactone delta-isomerase
LSO58_06200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO58_06215	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_06225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO58_06240	COG0543	2 iron, 2 sulfur cluster binding
LSO58_06240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LSO58_06245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LSO58_06250	COG4638	Rieske (2fe-2S)
LSO58_06255	COG3293	Transposase
LSO58_06275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LSO58_06285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LSO58_06290	COG1137	ATPase activity
LSO58_06325	COG4122	O-methyltransferase activity
LSO58_06335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LSO58_06345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LSO58_06375	COG1595	DNA-templated transcription, initiation
LSO58_06410	COG3152	Membrane
LSO58_06425	COG4774	siderophore transport
LSO58_06450	COG0657	acetylesterase activity
LSO58_06560	COG4968	Prepilin-type N-terminal cleavage methylation domain
LSO58_06585	COG4969	Belongs to the N-Me-Phe pilin family
LSO58_06605	COG4372	Transposase
LSO58_06645	COG5002	protein histidine kinase activity
LSO58_06655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSO58_07295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LSO58_07305	COG2175	clavaminate synthase activity
LSO58_07320	COG0024	Methionine aminopeptidase
LSO58_07325	COG0052	Belongs to the universal ribosomal protein uS2 family
LSO58_07330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LSO58_07365	COG2951	lytic endotransglycosylase activity
LSO58_07370	COG0772	Belongs to the SEDS family
LSO58_07380	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LSO58_07380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LSO58_07385	COG0842	Transport permease protein
LSO58_07390	COG1131	(ABC) transporter
LSO58_07430	COG0642	Histidine kinase
LSO58_07435	COG0745	RESPONSE REGULATOR receiver
LSO58_07440	COG2194	sulfuric ester hydrolase activity
LSO58_07455	COG0671	phosphoesterase, PA-phosphatase related
LSO58_07465	COG0589	response to stress
LSO58_07475	COG1686	Belongs to the peptidase S11 family
LSO58_07485	COG0352	thiamine-phosphate diphosphorylase activity
LSO58_07495	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LSO58_07500	COG0564	pseudouridine synthase activity
LSO58_07510	COG0783	Belongs to the Dps family
LSO58_07515	COG1309	transcriptional regulator
LSO58_07535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LSO58_07540	COG0076	glutamate decarboxylase activity
LSO58_07545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LSO58_07550	COG0573	inorganic phosphate transmembrane transporter activity
LSO58_07560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LSO58_07565	COG0616	signal peptide processing
LSO58_07580	COG2915	High frequency lysogenization protein hflD homolog
LSO58_07585	COG0482	sulfurtransferase activity
LSO58_07595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LSO58_07600	COG1686	Belongs to the peptidase S11 family
LSO58_07615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LSO58_07625	COG0583	DNA-binding transcription factor activity
LSO58_07630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LSO58_07635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LSO58_07655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LSO58_07660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LSO58_07665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LSO58_07680	COG4716	Myosin-crossreactive antigen
LSO58_07690	COG3706	GGDEF domain
LSO58_07700	COG1960	acyl-CoA dehydrogenase activity
LSO58_07705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LSO58_07765	COG0513	Belongs to the DEAD box helicase family
LSO58_07775	COG0778	Nitroreductase
LSO58_07800	COG0167	dihydroorotate dehydrogenase activity
LSO58_07805	COG1286	toxin biosynthetic process
LSO58_07830	COG4783	chaperone-mediated protein folding
LSO58_07840	COG1610	YqeY-like protein
LSO58_07860	COG0537	adenosine 5'-monophosphoramidase activity
LSO58_07890	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LSO58_07900	COG3100	YcgL domain-containing protein
LSO58_07910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSO58_07925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LSO58_07930	COG0360	Binds together with S18 to 16S ribosomal RNA
LSO58_07940	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LSO58_07945	COG1845	cytochrome c oxidase, subunit III
LSO58_07950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LSO58_07955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LSO58_07970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LSO58_07975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO58_07985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LSO58_07990	COG2890	protein-(glutamine-N5) methyltransferase activity
LSO58_07995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO58_08000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO58_08015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LSO58_08020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO58_08055	COG3042	response to heat
LSO58_08060	COG1968	undecaprenyl-diphosphatase activity
LSO58_08085	COG2207	Transcriptional regulator
LSO58_08090	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO58_08100	COG1960	acyl-CoA dehydrogenase activity
LSO58_08105	COG1960	acyl-CoA dehydrogenase activity
LSO58_08130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LSO58_08140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LSO58_08145	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LSO58_08155	COG2205	protein histidine kinase activity
LSO58_08160	COG0745	RESPONSE REGULATOR receiver
LSO58_08170	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LSO58_08180	COG0729	surface antigen
LSO58_08225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSO58_08235	COG2204	response regulator
LSO58_08240	COG3852	Histidine kinase
LSO58_08250	COG0528	UMP kinase activity
LSO58_08255	COG0233	cytoplasmic translational termination
LSO58_08260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LSO58_08265	COG0575	Belongs to the CDS family
LSO58_08290	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LSO58_08300	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LSO58_08315	COG2137	regulation of response to DNA damage stimulus
LSO58_08325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LSO58_08330	COG1011	Hydrolase
LSO58_08335	COG1218	3'(2'),5'-bisphosphate nucleotidase
LSO58_08345	COG3594	Acyltransferase
LSO58_08350	COG0268	Binds directly to 16S ribosomal RNA
LSO58_08355	COG0702	epimerase
LSO58_08360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LSO58_08375	COG0069	glutamate synthase activity
LSO58_08380	COG2850	peptidyl-arginine hydroxylation
LSO58_08390	COG0424	maF-like protein
LSO58_08400	COG0126	phosphoglycerate kinase activity
LSO58_08410	COG0191	fructose-bisphosphate aldolase activity
LSO58_08415	COG0697	spore germination
LSO58_08450	COG3698	Phosphodiester glycosidase
LSO58_08460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LSO58_08465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LSO58_08470	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LSO58_08470	COG0506	proline dehydrogenase activity
LSO58_08470	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LSO58_08480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LSO58_08485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LSO58_08490	COG0477	Major facilitator Superfamily
LSO58_08495	COG2267	carboxylic ester hydrolase activity
LSO58_08505	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSO58_08505	COG1902	pentaerythritol trinitrate reductase activity
LSO58_08525	COG0504	CTP synthase activity
LSO58_08535	COG0148	phosphopyruvate hydratase activity
LSO58_08545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LSO58_08550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO58_08560	COG1116	anion transmembrane transporter activity
LSO58_08560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO58_08565	COG0745	RESPONSE REGULATOR receiver
LSO58_08570	COG2223	nitrite transmembrane transporter activity
LSO58_08575	COG2146	nitrite reductase [NAD(P)H] activity
LSO58_08575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO58_08580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO58_08585	COG0243	molybdopterin cofactor binding
LSO58_08610	COG0315	cyclic pyranopterin monophosphate synthase activity
LSO58_08610	COG0521	Mo-molybdopterin cofactor biosynthetic process
LSO58_08615	COG0303	'Molybdopterin
LSO58_08620	COG0725	ABC transporter, periplasmic molybdate-binding protein
LSO58_08630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO58_08635	COG0697	spore germination
LSO58_08655	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LSO58_08660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LSO58_08690	COG1960	acyl-CoA dehydrogenase activity
LSO58_08730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LSO58_08740	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LSO58_08750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LSO58_08755	COG0509	glycine decarboxylation via glycine cleavage system
LSO58_08770	COG1132	(ABC) transporter
LSO58_08775	COG0668	transmembrane transport
LSO58_08780	COG3122	Protein conserved in bacteria
LSO58_08795	COG0640	Transcriptional regulator
LSO58_08840	COG1538	Outer membrane efflux protein
LSO58_08845	COG1595	DNA-templated transcription, initiation
LSO58_08860	COG1027	Aspartate ammonia-lyase
LSO58_08865	COG0583	DNA-binding transcription factor activity
LSO58_08870	COG1846	Transcriptional regulator
LSO58_08880	COG3676	manually curated
LSO58_08890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO58_08895	COG1414	Transcriptional regulator
LSO58_08900	COG4993	Dehydrogenase
LSO58_08905	COG3659	wide pore channel activity
LSO58_08910	COG3420	alginic acid biosynthetic process
LSO58_08915	COG0710	3-dehydroquinate dehydratase activity
LSO58_08920	COG3485	protocatechuate 3,4-dioxygenase
LSO58_08925	COG3485	protocatechuate 3,4-dioxygenase
LSO58_08930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LSO58_08935	COG2271	Major facilitator Superfamily
LSO58_08940	COG0596	Alpha beta hydrolase
LSO58_08945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LSO58_08950	COG0183	Belongs to the thiolase family
LSO58_08955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LSO58_08960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LSO58_08965	COG1414	Transcriptional regulator
LSO58_08975	COG0583	DNA-binding transcription factor activity
LSO58_08980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LSO58_08985	COG0235	Class ii aldolase
LSO58_08990	COG1024	Enoyl-CoA hydratase
LSO58_08995	COG1960	acyl-CoA dehydrogenase activity
LSO58_09005	COG2814	Major facilitator Superfamily
LSO58_09015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LSO58_09025	COG2814	Major facilitator Superfamily
LSO58_09030	COG2814	Major facilitator Superfamily
LSO58_09035	COG1960	acyl-CoA dehydrogenase activity
LSO58_09040	COG1024	Enoyl-CoA hydratase
LSO58_09045	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_09050	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSO58_09055	COG0183	Belongs to the thiolase family
LSO58_09070	COG2814	Major facilitator Superfamily
LSO58_09085	COG2814	Major facilitator Superfamily
LSO58_09090	COG0644	oxidoreductase
LSO58_09090	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LSO58_09140	COG0583	DNA-binding transcription factor activity
LSO58_09145	COG1380	Effector of murein hydrolase LrgA
LSO58_09150	COG1346	cytolysis
LSO58_09165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LSO58_09180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LSO58_09190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LSO58_09200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LSO58_09235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LSO58_09240	COG2814	Major facilitator Superfamily
LSO58_09245	COG1960	acyl-CoA dehydrogenase activity
LSO58_09250	COG0583	DNA-binding transcription factor activity
LSO58_09260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSO58_09265	COG0583	DNA-binding transcription factor activity
LSO58_09270	COG0024	Methionine aminopeptidase
LSO58_09330	COG2814	Major facilitator Superfamily
LSO58_09335	COG1082	Xylose isomerase domain protein TIM barrel
LSO58_09345	COG0667	Aldo Keto reductase
LSO58_09355	COG1053	succinate dehydrogenase
LSO58_09360	COG1053	succinate dehydrogenase
LSO58_09370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LSO58_09390	COG1309	transcriptional regulator
LSO58_09395	COG3659	wide pore channel activity
LSO58_09410	COG1053	succinate dehydrogenase
LSO58_09415	COG1414	Transcriptional regulator
LSO58_09420	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_09430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSO58_09460	COG0822	iron-sulfur transferase activity
LSO58_09465	COG0316	Belongs to the HesB IscA family
LSO58_09495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LSO58_09515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LSO58_09520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LSO58_09525	COG1454	alcohol dehydrogenase
LSO58_09530	COG0824	Thioesterase
LSO58_09555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LSO58_09560	COG2030	dehydratase
LSO58_09565	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_09595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LSO58_09605	COG3135	benzoate transporter
LSO58_09615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LSO58_09630	COG0589	response to stress
LSO58_09640	COG0308	aminopeptidase N
LSO58_09655	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LSO58_09660	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LSO58_09670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSO58_09675	COG1454	alcohol dehydrogenase
LSO58_09695	COG0505	Belongs to the CarA family
LSO58_09705	COG2353	YceI-like domain
LSO58_09720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LSO58_09725	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LSO58_09755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LSO58_09755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LSO58_09765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LSO58_09780	COG2193	ferroxidase activity
LSO58_09785	COG4774	siderophore transport
LSO58_09800	COG0217	transcriptional regulatory protein
LSO58_09815	COG1126	abc transporter atp-binding protein
LSO58_09820	COG0765	amino acid transport
LSO58_09825	COG0765	amino acid transport
LSO58_09850	COG0542	response to heat
LSO58_09855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LSO58_09865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LSO58_09880	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LSO58_09885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LSO58_09890	COG0569	domain protein
LSO58_09895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LSO58_09910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LSO58_09920	COG1585	Membrane protein implicated in regulation of membrane protease activity
LSO58_09935	COG1294	oxidase, subunit
LSO58_09940	COG4890	Cyd operon protein YbgT
LSO58_09960	COG0552	protein localization to endoplasmic reticulum
LSO58_09995	COG0517	IMP dehydrogenase activity
LSO58_09995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LSO58_10000	COG0305	Participates in initiation and elongation during chromosome replication
LSO58_10005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LSO58_10020	COG1305	Transglutaminase-like
LSO58_10030	COG2308	Evidence 4 Homologs of previously reported genes of
LSO58_10040	COG0445	tRNA wobble uridine modification
LSO58_10065	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LSO58_10070	COG0138	bifunctional purine biosynthesis protein purh
LSO58_10080	COG1464	Belongs to the NlpA lipoprotein family
LSO58_10085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LSO58_10090	COG2011	ABC-type metal ion transport system permease component
LSO58_10135	COG2815	serine threonine protein kinase
LSO58_10135	COG0515	serine threonine protein kinase
LSO58_10170	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LSO58_10175	COG4773	Receptor
LSO58_10195	COG0730	response to heat
LSO58_10200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LSO58_10210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LSO58_10225	COG1253	flavin adenine dinucleotide binding
LSO58_10245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LSO58_10265	COG0284	orotidine-5'-phosphate decarboxylase activity
LSO58_10280	COG0776	regulation of translation
LSO58_10290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LSO58_10345	COG0084	hydrolase, TatD family'
LSO58_10365	COG1663	tetraacyldisaccharide 4'-kinase activity
LSO58_10370	COG1132	(ABC) transporter
LSO58_10380	COG0811	peptide transport
LSO58_10385	COG1475	DNA binding
LSO58_10390	COG1192	Involved in chromosome partitioning
LSO58_10395	COG0357	Ribosomal RNA small subunit methyltransferase G
LSO58_10400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LSO58_10410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LSO58_10415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LSO58_10420	COG1923	regulation of RNA biosynthetic process
LSO58_10425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LSO58_10430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LSO58_10435	COG0802	atpase or kinase
LSO58_10440	COG0564	pseudouridine synthase activity
LSO58_10470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LSO58_10480	COG2707	UPF0756 membrane protein
LSO58_10490	COG0583	DNA-binding transcription factor activity
LSO58_10500	COG2814	Major facilitator Superfamily
LSO58_10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LSO58_10510	COG0471	metal ion transport
LSO58_10515	COG1012	belongs to the aldehyde dehydrogenase family
LSO58_10540	COG1464	Belongs to the NlpA lipoprotein family
LSO58_10545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LSO58_10550	COG2011	ABC-type metal ion transport system permease component
LSO58_10555	COG0012	GTP binding
LSO58_10560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LSO58_10580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LSO58_10585	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LSO58_10610	COG0386	Belongs to the glutathione peroxidase family
LSO58_10615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LSO58_10620	COG0436	Aminotransferase
LSO58_10665	COG3706	GGDEF domain
LSO58_10690	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LSO58_10695	COG0596	Alpha beta hydrolase
LSO58_10705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO58_10715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO58_10725	COG0714	Associated with various cellular activities
LSO58_10730	COG2879	small protein
LSO58_10735	COG1966	Carbon starvation protein
LSO58_10740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LSO58_10745	COG1509	lysine 2,3-aminomutase activity
LSO58_10775	COG2433	Pfam Transposase IS66
LSO58_10780	COG4625	pathogenesis
LSO58_10790	COG0602	queuosine metabolic process
LSO58_10795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LSO58_10805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LSO58_10810	COG2353	YceI-like domain
LSO58_10815	COG1051	belongs to the nudix hydrolase family
LSO58_10815	COG1056	cytidyltransferase-related domain
LSO58_10820	COG1024	Enoyl-CoA hydratase
LSO58_10830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LSO58_10830	COG3323	Protein of unknown function (DUF1653)
LSO58_10840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LSO58_10840	COG0047	phosphoribosylformylglycinamidine synthase activity
LSO58_10850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LSO58_10850	COG3008	intermembrane lipid transfer
LSO58_10855	COG2995	paraquat-inducible protein a
LSO58_10900	COG0540	Belongs to the ATCase OTCase family
LSO58_10905	COG0116	Belongs to the methyltransferase superfamily
LSO58_10905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LSO58_10930	COG1765	OsmC-like protein
LSO58_10940	COG0667	Aldo Keto reductase
LSO58_10955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LSO58_10960	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LSO58_10975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LSO58_10990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LSO58_11005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LSO58_11010	COG2252	PERMEase
LSO58_11020	COG0659	secondary active sulfate transmembrane transporter activity
LSO58_11030	COG1301	dicarboxylic acid transport
LSO58_11035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LSO58_11040	COG3139	Protein of unknown function (DUF1315)
LSO58_11045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LSO58_11050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LSO58_11060	COG0494	nUDIX hydrolase
LSO58_11070	COG0642	Histidine kinase
LSO58_11080	COG3111	PFAM Bacterial OB fold (BOF) protein
LSO58_11085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LSO58_11090	COG3706	GGDEF domain
LSO58_11095	COG1720	tRNA m6t6A37 methyltransferase activity
LSO58_11105	COG1335	isochorismatase
LSO58_11110	COG3384	dioxygenase
LSO58_11115	COG0826	peptidase U32
LSO58_11120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LSO58_11145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LSO58_11150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LSO58_11170	COG1301	dicarboxylic acid transport
LSO58_11180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LSO58_11200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LSO58_11205	COG1381	Involved in DNA repair and RecF pathway recombination
LSO58_11215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LSO58_11220	COG0571	ribonuclease III activity
LSO58_11230	COG0681	Belongs to the peptidase S26 family
LSO58_11235	COG0481	GTPase activity
LSO58_11245	COG0174	glutamine synthetase
LSO58_11250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSO58_11260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LSO58_11265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LSO58_11270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LSO58_11275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LSO58_11285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LSO58_11290	COG4208	sulfate ABC transporter
LSO58_11295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LSO58_11300	COG0583	DNA-binding transcription factor activity
LSO58_11305	COG0254	rRNA binding
LSO58_11320	COG1067	ATP-dependent peptidase activity
LSO58_11325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LSO58_11330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LSO58_11335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LSO58_11340	COG0512	Glutamine amidotransferase of anthranilate synthase
LSO58_11345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LSO58_11350	COG0134	indole-3-glycerol-phosphate synthase activity
LSO58_11365	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LSO58_11365	COG3608	succinylglutamate desuccinylase aspartoacylase
LSO58_11370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LSO58_11380	COG0302	gtp cyclohydrolase
LSO58_11385	COG0586	Pfam SNARE associated Golgi protein
LSO58_11395	COG3739	integral membrane protein
LSO58_11400	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LSO58_11410	COG1741	Belongs to the pirin family
LSO58_11415	COG3421	Type III restriction
LSO58_11420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LSO58_11445	COG0842	Transport permease protein
LSO58_11450	COG1131	(ABC) transporter
LSO58_11465	COG0583	DNA-binding transcription factor activity
LSO58_11475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LSO58_11480	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LSO58_11490	COG0037	tRNA processing
LSO58_11495	COG1196	nuclear chromosome segregation
LSO58_11495	COG0739	heme binding
LSO58_11495	COG0741	lytic transglycosylase activity
LSO58_11500	COG0501	Belongs to the peptidase M48B family
LSO58_11510	COG2239	Acts as a magnesium transporter
LSO58_11515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO58_11540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LSO58_11545	COG2188	Transcriptional regulator
LSO58_11555	COG1045	serine acetyltransferase
LSO58_11560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LSO58_11565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LSO58_11570	COG0459	protein refolding
LSO58_11575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LSO58_11590	COG1597	lipid kinase activity
LSO58_11595	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LSO58_11620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LSO58_11640	COG1929	Belongs to the glycerate kinase type-1 family
LSO58_11660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LSO58_11665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LSO58_11670	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LSO58_11690	COG0505	Belongs to the CarA family
LSO58_11710	COG0589	response to stress
LSO58_11720	COG0589	response to stress
LSO58_11730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LSO58_11740	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LSO58_11745	COG4181	ATPase activity
LSO58_11755	COG0288	reversible hydration of carbon dioxide
LSO58_11770	COG4771	TonB-dependent receptor
LSO58_11775	COG4771	TonB-dependent receptor
LSO58_11795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LSO58_11815	COG0306	phosphate transporter
LSO58_11825	COG0653	protein targeting
LSO58_11830	COG2852	Protein conserved in bacteria
LSO58_11860	COG2223	nitrite transmembrane transporter activity
LSO58_11870	COG2066	Belongs to the glutaminase family
LSO58_11875	COG0242	peptide deformylase activity
LSO58_11880	COG0561	phosphatase activity
LSO58_11895	COG0400	carboxylic ester hydrolase activity
LSO58_11925	COG1215	transferase activity, transferring glycosyl groups
LSO58_11930	COG0726	polysaccharide deacetylase
LSO58_11930	COG1649	PFAM Uncharacterised BCR, COG1649
LSO58_11945	COG4681	YaeQ
LSO58_11955	COG0523	cobalamin synthesis protein
LSO58_11970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LSO58_11970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LSO58_11990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LSO58_12005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LSO58_12010	COG1773	rubredoxin
LSO58_12015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LSO58_12025	COG0583	DNA-binding transcription factor activity
LSO58_12055	COG1733	regulation of RNA biosynthetic process
LSO58_12065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LSO58_12070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LSO58_12070	COG1648	precorrin-2 dehydrogenase activity
LSO58_12075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LSO58_12085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LSO58_12095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LSO58_12100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LSO58_12115	COG0671	phosphoesterase, PA-phosphatase related
LSO58_12120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO58_12130	COG1538	Outer membrane efflux protein
LSO58_12135	COG0393	Putative heavy-metal-binding
LSO58_12140	COG0393	Putative heavy-metal-binding
LSO58_12145	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_12155	COG0525	valine-tRNA ligase activity
LSO58_12170	COG0004	ammonium transporteR
LSO58_12185	COG0745	RESPONSE REGULATOR receiver
LSO58_12190	COG2814	Major facilitator Superfamily
LSO58_12200	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSO58_12215	COG0142	geranyltranstransferase activity
LSO58_12225	COG2828	Protein conserved in bacteria
LSO58_12230	COG1113	amino acid transport
LSO58_12250	COG0658	competence protein
LSO58_12250	COG2333	competence protein COMEC
LSO58_12255	COG1136	(ABC) transporter
LSO58_12275	COG1671	Belongs to the UPF0178 family
LSO58_12285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LSO58_12295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO58_12335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LSO58_12350	COG3384	dioxygenase
LSO58_12360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LSO58_12365	COG2878	Part of a membrane complex involved in electron transport
LSO58_12370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LSO58_12380	COG0563	adenylate kinase activity
LSO58_12395	COG0768	penicillin binding
LSO58_12400	COG0742	ribosomal rna small subunit methyltransferase
LSO58_12425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LSO58_12430	COG0830	nickel cation binding
LSO58_12435	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LSO58_12440	COG0804	urea catabolic process
LSO58_12445	COG0832	Belongs to the urease beta subunit family
LSO58_12450	COG0831	urea catabolic process
LSO58_12455	COG0829	nickel cation binding
LSO58_12470	COG3015	lipoprotein NlpE involved in copper resistance
LSO58_12490	COG1253	flavin adenine dinucleotide binding
LSO58_12500	COG1116	anion transmembrane transporter activity
LSO58_12520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LSO58_12530	COG0864	Transcriptional regulator
LSO58_12540	COG0439	Biotin carboxylase
LSO58_12575	COG2851	Citrate transporter
LSO58_12585	COG0175	sulfate reduction
LSO58_12590	COG1492	cobalamin metabolic process
LSO58_12615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LSO58_12625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LSO58_12655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LSO58_12695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LSO58_12705	COG0193	aminoacyl-tRNA hydrolase activity
LSO58_12715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LSO58_12725	COG1054	Belongs to the UPF0176 family
LSO58_12740	COG0586	Pfam SNARE associated Golgi protein
LSO58_12745	COG0500	methyltransferase
LSO58_12770	COG0321	lipoyl(octanoyl) transferase activity
LSO58_12785	COG0531	amino acid
LSO58_12790	COG2321	neutral zinc metallopeptidase
LSO58_12795	COG2354	Protein conserved in bacteria
LSO58_12805	COG1585	Membrane protein implicated in regulation of membrane protease activity
LSO58_12810	COG2268	Band 7 protein
LSO58_12825	COG1215	transferase activity, transferring glycosyl groups
LSO58_12830	COG0726	polysaccharide deacetylase
LSO58_12830	COG1649	PFAM Uncharacterised BCR, COG1649
LSO58_12845	COG0045	succinate-CoA ligase (ADP-forming) activity
LSO58_12850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LSO58_12865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LSO58_12870	COG1053	succinate dehydrogenase
LSO58_12875	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LSO58_12880	COG2009	succinate dehydrogenase
LSO58_12890	COG1607	acyl-coa hydrolase
LSO58_12900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LSO58_12905	COG1309	transcriptional regulator
LSO58_12910	COG1012	belongs to the aldehyde dehydrogenase family
LSO58_12915	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LSO58_12940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LSO58_12945	COG1120	ATPase activity
LSO58_12960	COG0028	Belongs to the TPP enzyme family
LSO58_12965	COG1012	belongs to the aldehyde dehydrogenase family
LSO58_12970	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LSO58_12975	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_12990	COG2271	Major facilitator Superfamily
LSO58_12995	COG0446	pyridine nucleotide-disulphide oxidoreductase
LSO58_13005	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_13025	COG1414	Transcriptional regulator
LSO58_13050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LSO58_13075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSO58_13085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LSO58_13095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LSO58_13105	COG0084	hydrolase, TatD family'
LSO58_13120	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LSO58_13135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LSO58_13145	COG0028	Belongs to the TPP enzyme family
LSO58_13170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LSO58_13175	COG0577	efflux transmembrane transporter activity
LSO58_13175	COG1136	(ABC) transporter
LSO58_13190	COG2223	nitrite transmembrane transporter activity
LSO58_13220	COG0583	DNA-binding transcription factor activity
LSO58_13225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LSO58_13230	COG0436	Aminotransferase
LSO58_13235	COG1301	dicarboxylic acid transport
LSO58_13240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LSO58_13250	COG2223	nitrite transmembrane transporter activity
LSO58_13255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LSO58_13295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO58_13300	COG2814	Major facilitator Superfamily
LSO58_13305	COG1566	PFAM secretion protein HlyD family protein
LSO58_13310	COG2050	protein possibly involved in aromatic compounds catabolism
LSO58_13335	COG0420	3'-5' exonuclease activity
LSO58_13350	COG1011	Hydrolase
LSO58_13355	COG1968	undecaprenyl-diphosphatase activity
LSO58_13375	COG0735	belongs to the Fur family
LSO58_13380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LSO58_13385	COG2914	Belongs to the UPF0125 (RnfH) family
LSO58_13400	COG0121	glutamine amidotransferase
LSO58_13410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LSO58_13415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LSO58_13420	COG0756	dUTP diphosphatase activity
LSO58_13430	COG2885	chlorophyll binding
LSO58_13435	COG0204	Acyl-transferase
LSO58_13445	COG0850	regulation of cytokinetic process
LSO58_13450	COG2894	cell division
LSO58_13455	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LSO58_13465	COG1280	lysine exporter protein (LysE YggA)
LSO58_13475	COG0531	amino acid
LSO58_13475	COG1674	ftsk spoiiie
LSO58_13480	COG0492	ferredoxin-NADP+ reductase activity
LSO58_13485	COG0500	methyltransferase
LSO58_13490	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LSO58_13495	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LSO58_13500	COG0456	acetyltransferase
LSO58_13510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LSO58_13515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LSO58_13540	COG1981	membrane
LSO58_13560	COG0352	thiamine-phosphate diphosphorylase activity
LSO58_13560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LSO58_13560	COG0351	phosphomethylpyrimidine kinase
LSO58_13565	COG1733	regulation of RNA biosynthetic process
LSO58_13575	COG1652	LysM domain
LSO58_13585	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_13600	COG1399	metal-binding, possibly nucleic acid-binding protein
LSO58_13605	COG3101	peptidyl-lysine hydroxylation
LSO58_13610	COG0009	L-threonylcarbamoyladenylate synthase
LSO58_13620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LSO58_13625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LSO58_13645	COG4106	trans-aconitate 2-methyltransferase activity
LSO58_13655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LSO58_13655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LSO58_13670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LSO58_13685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LSO58_13695	COG1196	nuclear chromosome segregation
LSO58_13705	COG0730	response to heat
LSO58_13710	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LSO58_13710	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LSO58_13720	COG3545	Serine hydrolase
LSO58_13725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LSO58_13735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LSO58_13750	COG3422	double-strand break repair
LSO58_13755	COG0494	nUDIX hydrolase
LSO58_13760	COG2824	Alkylphosphonate utilization operon protein PhnA
LSO58_13775	COG1752	Esterase of the alpha-beta hydrolase superfamily
LSO58_13780	COG1115	amino acid carrier protein
LSO58_13785	COG0786	glutamate:sodium symporter activity
LSO58_13800	COG2814	Major facilitator Superfamily
LSO58_13805	COG1289	transmembrane transporter activity
LSO58_13815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LSO58_13860	COG1376	ErfK ybiS ycfS ynhG family protein
LSO58_13865	COG2832	Protein of unknown function (DUF454)
LSO58_13875	COG5510	response to toxic substance
LSO58_13880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LSO58_13895	COG0183	Belongs to the thiolase family
LSO58_13925	COG1956	GAF domain-containing protein
LSO58_13930	COG1607	acyl-coa hydrolase
LSO58_13990	COG2199	diguanylate cyclase activity
LSO58_13995	COG2885	chlorophyll binding
LSO58_14020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LSO58_14025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LSO58_14035	COG0653	protein targeting
LSO58_14040	COG0450	alkyl hydroperoxide reductase
LSO58_14060	COG0285	dihydrofolate synthase activity
LSO58_14065	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LSO58_14105	COG4206	TonB-dependent receptor
LSO58_14110	COG2096	Adenosyltransferase
LSO58_14130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LSO58_14150	COG0784	Response regulator, receiver
LSO58_14150	COG2205	protein histidine kinase activity
LSO58_14150	COG5002	protein histidine kinase activity
LSO58_14160	COG2084	Dehydrogenase
LSO58_14165	COG3622	Belongs to the hyi family
LSO58_14190	COG0740	serine-type endopeptidase activity
LSO58_14195	COG0544	peptidyl-prolyl cis-trans isomerase activity
LSO58_14200	COG4774	siderophore transport
LSO58_14205	COG3128	pkhd-type hydroxylase
LSO58_14210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LSO58_14215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO58_14220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LSO58_14220	COG2813	Specifically methylates the guanine in position
LSO58_14230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LSO58_14265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LSO58_14280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LSO58_14320	COG0788	formyltetrahydrofolate deformylase activity
LSO58_14325	COG1309	transcriptional regulator
LSO58_14345	COG4651	solute:proton antiporter activity
LSO58_14345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LSO58_14365	COG0210	DNA helicase
LSO58_14375	COG3706	GGDEF domain
LSO58_14375	COG4251	negative regulation of phosphorylation
LSO58_14375	COG5001	Diguanylate cyclase
LSO58_14375	COG2203	Gaf domain
LSO58_14405	COG2900	Belongs to the SlyX family
LSO58_14410	COG0488	(ABC) transporter
LSO58_14420	COG1560	Kdo2-lipid A biosynthetic process
LSO58_14425	COG0438	transferase activity, transferring glycosyl groups
LSO58_14430	COG1301	dicarboxylic acid transport
LSO58_14465	COG0101	tRNA pseudouridine synthase activity
LSO58_14470	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_14480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LSO58_14490	COG0473	3-isopropylmalate dehydrogenase activity
LSO58_14505	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LSO58_14520	COG0583	DNA-binding transcription factor activity
LSO58_14535	COG0494	nUDIX hydrolase
LSO58_14545	COG1960	acyl-CoA dehydrogenase activity
LSO58_14555	COG0753	catalase activity
LSO58_14560	COG4993	Dehydrogenase
LSO58_14575	COG0583	DNA-binding transcription factor activity
LSO58_14590	COG0564	pseudouridine synthase activity
LSO58_14595	COG1530	ribonuclease E activity
LSO58_14600	COG0318	PFAM AMP-dependent synthetase and ligase
LSO58_14615	COG0450	alkyl hydroperoxide reductase
LSO58_14620	COG0583	DNA-binding transcription factor activity
LSO58_14625	COG4221	oxidoreductase activity
LSO58_14635	COG1595	DNA-templated transcription, initiation
LSO58_14645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LSO58_14655	COG0534	Mate efflux family protein
LSO58_14670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LSO58_14675	COG0254	rRNA binding
LSO58_14690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO58_14710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LSO58_14710	COG0493	'glutamate synthase
LSO58_14720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LSO58_14730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LSO58_14735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LSO58_14745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LSO58_14755	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LSO58_14755	COG0644	oxidoreductase
LSO58_14770	COG0425	Belongs to the sulfur carrier protein TusA family
LSO58_14775	COG4535	Mg2 and Co2 transporter CorC
LSO58_14780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LSO58_14785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LSO58_14805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LSO58_14815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LSO58_14820	COG0484	heat shock protein binding
LSO58_14835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LSO58_14840	COG0598	Magnesium transport protein CorA
LSO58_14845	COG2841	Protein conserved in bacteria
LSO58_14850	COG1185	polyribonucleotide nucleotidyltransferase activity
LSO58_14855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LSO58_14860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LSO58_14865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LSO58_14870	COG1074	ATP-dependent DNA helicase activity
LSO58_14875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LSO58_14900	COG2226	methyltransferase
LSO58_14910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LSO58_14935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LSO58_14935	COG2111	Na H antiporter
LSO58_14940	COG1006	Multisubunit Na H antiporter MnhC subunit
LSO58_14945	COG0651	ATP synthesis coupled electron transport
LSO58_14950	COG1863	multisubunit Na H antiporter MnhE subunit
LSO58_14955	COG2212	antiporter activity
LSO58_14960	COG1320	monovalent cation:proton antiporter activity
LSO58_14975	COG0195	Participates in both transcription termination and antitermination
LSO58_14980	COG0779	Required for maturation of 30S ribosomal subunits
LSO58_15005	COG0149	triose-phosphate isomerase activity
LSO58_15025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LSO58_15030	COG0237	dephospho-CoA kinase activity
LSO58_15040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LSO58_15045	COG3123	guanosine phosphorylase activity
LSO58_15050	COG0497	DNA recombination
LSO58_15055	COG1678	Uncharacterized ACR, COG1678
LSO58_15060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LSO58_15075	COG1289	transmembrane transporter activity
LSO58_15085	COG1132	(ABC) transporter
LSO58_15095	COG2169	Transcriptional regulator
LSO58_15095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LSO58_15100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LSO58_15125	COG1024	Enoyl-CoA hydratase
LSO58_15125	COG1250	3-hydroxyacyl-CoA dehydrogenase
LSO58_15150	COG3307	-O-antigen
LSO58_15160	COG3307	-O-antigen
LSO58_15165	COG4969	Belongs to the N-Me-Phe pilin family
LSO58_15175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LSO58_15180	COG1704	LemA family
LSO58_15190	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_15200	COG0493	'glutamate synthase
LSO58_15205	COG0069	glutamate synthase activity
LSO58_15205	COG0070	glutamate synthase
LSO58_15205	COG0067	glutamate synthase
LSO58_15215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LSO58_15220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LSO58_15255	COG2226	methyltransferase
LSO58_15260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LSO58_15265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LSO58_15270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LSO58_15285	COG0275	rRNA processing
LSO58_15300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LSO58_15350	COG0488	(ABC) transporter
LSO58_15355	COG0028	Belongs to the TPP enzyme family
LSO58_15365	COG4221	oxidoreductase activity
LSO58_15395	COG0427	acetyl-CoA hydrolase
LSO58_15400	COG0456	acetyltransferase
LSO58_15430	COG0131	Imidazoleglycerol-phosphate dehydratase
LSO58_15435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LSO58_15445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LSO58_15465	COG1132	(ABC) transporter
LSO58_15470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO58_15475	COG0531	amino acid
LSO58_15495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LSO58_15535	COG3158	transport of potassium into the cell
LSO58_15545	COG0582	viral genome integration into host DNA
LSO58_15555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LSO58_15650	COG3177	Filamentation induced by cAMP protein fic
LSO58_15680	COG4372	Transposase
LSO58_15725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LSO58_15735	COG0179	Fumarylacetoacetate (FAA) hydrolase
LSO58_15750	COG2814	Major facilitator Superfamily
LSO58_15760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LSO58_15795	COG3706	GGDEF domain
LSO58_15815	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LSO58_15825	COG1335	isochorismatase
LSO58_15885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LSO58_15890	COG1113	amino acid transport
LSO58_15895	COG0251	oxidation-reduction process
LSO58_15905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO58_15915	COG1448	Aminotransferase
LSO58_15925	COG0277	FAD linked oxidase domain protein
LSO58_15930	COG1304	FMN binding
LSO58_15935	COG2186	Transcriptional regulator
LSO58_15940	COG1620	l-lactate permease
LSO58_15945	COG0583	DNA-binding transcription factor activity
LSO58_15950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LSO58_15965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LSO58_15980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LSO58_15985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LSO58_15990	COG1216	Glycosyl transferase, family 2
LSO58_16000	COG1216	Glycosyl transferase, family 2
LSO58_16010	COG1442	glycosyl transferase family 8
LSO58_16010	COG1216	Glycosyl transferase, family 2
LSO58_16020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LSO58_16025	COG1596	polysaccharide export
LSO58_16055	COG3023	N-Acetylmuramoyl-L-alanine amidase
LSO58_16075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LSO58_16105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LSO58_16110	COG0546	phosphoglycolate phosphatase activity
LSO58_16115	COG1028	Short-chain dehydrogenase reductase Sdr
LSO58_16135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LSO58_16135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LSO58_16140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO58_16145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LSO58_16150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO58_16155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LSO58_16160	COG1116	anion transmembrane transporter activity
LSO58_16170	COG2233	PERMEase
LSO58_16175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LSO58_16180	COG0251	oxidation-reduction process
LSO58_16185	COG1335	isochorismatase
LSO58_16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LSO58_16195	COG1309	transcriptional regulator
LSO58_16200	COG0596	Alpha beta hydrolase
LSO58_16215	COG0196	riboflavin kinase activity
LSO58_16220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LSO58_16225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LSO58_16230	COG1047	Peptidyl-prolyl cis-trans
LSO58_16275	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LSO58_16275	COG2885	chlorophyll binding
LSO58_16400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LSO58_16405	COG0657	acetylesterase activity
LSO58_16425	COG0583	DNA-binding transcription factor activity
LSO58_16430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LSO58_16435	COG0443	Heat shock 70 kDa protein
LSO58_16450	COG2951	lytic endotransglycosylase activity
LSO58_16455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LSO58_16470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LSO58_16495	COG0861	Integral membrane protein TerC family
LSO58_16505	COG0402	S-adenosylhomocysteine deaminase activity
LSO58_16520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LSO58_16530	COG0706	membrane insertase activity
LSO58_16535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LSO58_16540	COG0594	ribonuclease P activity
LSO58_16685	COG1475	DNA binding
LSO58_16690	COG1192	Involved in chromosome partitioning
LSO58_16940	COG1660	Displays ATPase and GTPase activities
LSO58_17030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO58_17140	COG1538	Outer membrane efflux protein
LSO58_17145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO58_17155	COG0745	RESPONSE REGULATOR receiver
LSO58_17160	COG2205	protein histidine kinase activity
LSO58_17175	COG3173	Aminoglycoside phosphotransferase
LSO58_17180	COG0488	(ABC) transporter
LSO58_17205	COG2433	Pfam Transposase IS66
LSO58_17280	COG0860	N-Acetylmuramoyl-L-alanine amidase
LSO58_17370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LSO58_17415	COG3421	Type III restriction
LSO58_17420	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LSO58_17430	COG1525	nuclease
LSO58_17480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LSO58_17630	COG2826	transposase and inactivated derivatives, IS30 family
LSO58_17815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LSO58_17820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSO58_17850	COG2369	cell adhesion
LSO58_17855	COG0582	viral genome integration into host DNA
LSO58_17910	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LSO58_17935	COG2132	Multicopper oxidase
LSO58_17950	COG2205	protein histidine kinase activity
LSO58_17955	COG3174	membrane
LSO58_17960	COG2217	Heavy metal translocating P-type atpase
LSO58_17985	COG0431	NADPH-dependent FMN reductase
LSO58_17990	COG0798	PFAM Bile acid sodium symporter
LSO58_18000	COG0640	Transcriptional regulator
LSO58_18010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LSO58_18050	COG2233	PERMEase
LSO58_18070	COG0583	DNA-binding transcription factor activity
LSO58_18150	COG4372	Transposase
LSO58_18180	COG2072	flavoprotein involved in K transport
LSO58_18400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LSO58_18475	COG0739	heme binding
LSO58_18615	COG0501	Belongs to the peptidase M48B family
LSO58_18620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LSO58_18670	COG4974	Belongs to the 'phage' integrase family
LSO58_18700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LSO58_18760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LSO58_18780	COG2323	membrane
LSO58_18825	COG2223	nitrite transmembrane transporter activity
LSO58_18830	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LSO58_18835	COG1877	trehalose-phosphatase activity
LSO58_18850	COG1570	exodeoxyribonuclease VII activity
LSO58_18880	COG1309	transcriptional regulator
LSO58_18885	COG0604	alcohol dehydrogenase
LSO58_18915	COG4115	mRNA cleavage
LSO58_18955	COG2026	Addiction module toxin, RelE StbE family
LSO58_18970	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LSO58_18990	COG0582	viral genome integration into host DNA
LSO58_19005	COG2130	NADP-dependent
LSO58_19010	COG1309	transcriptional regulator
LSO58_19020	COG1902	pentaerythritol trinitrate reductase activity
LSO58_19030	COG1979	alcohol dehydrogenase
LSO58_19045	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LSO58_19060	COG0604	alcohol dehydrogenase
LSO58_19060	COG3321	synthase
LSO58_19065	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LSO58_19070	COG0583	DNA-binding transcription factor activity
LSO58_19075	COG4221	oxidoreductase activity
LSO58_19115	COG3706	GGDEF domain
LSO58_19130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LSO58_19140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LSO58_19145	COG1113	amino acid transport
LSO58_19150	COG0697	spore germination
LSO58_19210	COG1475	DNA binding
LSO58_19215	COG1192	Involved in chromosome partitioning