locus-tag	class	description
N5980_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N5980_00010	COG0592	DNA-directed DNA polymerase activity
N5980_00020	COG0187	DNA topoisomerase II activity
N5980_00030	COG1063	alcohol dehydrogenase
N5980_00035	COG0488	(ABC) transporter
N5980_00090	COG0657	acetylesterase activity
N5980_00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N5980_00130	COG2814	Major facilitator Superfamily
N5980_00135	COG2814	Major facilitator Superfamily
N5980_00150	COG0693	protein deglycase activity
N5980_00160	COG1012	belongs to the aldehyde dehydrogenase family
N5980_00165	COG0733	neurotransmitter:sodium symporter activity
N5980_00175	COG0428	transporter
N5980_00190	COG0129	dihydroxy-acid dehydratase activity
N5980_00195	COG0129	dihydroxy-acid dehydratase activity
N5980_00220	COG2233	PERMEase
N5980_00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5980_00275	COG0675	Transposase, IS605 OrfB family
N5980_00290	COG2814	Major facilitator Superfamily
N5980_00295	COG0656	L-ascorbic acid biosynthetic process
N5980_00300	COG0583	DNA-binding transcription factor activity
N5980_00305	COG1064	alcohol dehydrogenase
N5980_00310	COG2818	Glycosylase
N5980_00320	COG0739	heme binding
N5980_00325	COG1194	a g-specific adenine glycosylase
N5980_00370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N5980_00385	COG1091	dTDP-4-dehydrorhamnose reductase activity
N5980_00410	COG2030	dehydratase
N5980_00430	COG0438	transferase activity, transferring glycosyl groups
N5980_00435	COG0438	transferase activity, transferring glycosyl groups
N5980_00455	COG0438	transferase activity, transferring glycosyl groups
N5980_00460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N5980_00470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N5980_00480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N5980_00495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N5980_00550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N5980_00560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N5980_00565	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N5980_00575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N5980_00600	COG4628	conserved protein (DUF2132)
N5980_00625	COG2826	transposase and inactivated derivatives, IS30 family
N5980_00650	COG0737	Belongs to the 5'-nucleotidase family
N5980_00690	COG3293	Transposase
N5980_00710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N5980_00710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N5980_00715	COG1105	Belongs to the carbohydrate kinase PfkB family
N5980_00720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5980_00720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N5980_00720	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N5980_00730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N5980_00735	COG3550	peptidyl-serine autophosphorylation
N5980_00805	COG0753	catalase activity
N5980_00820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N5980_00885	COG1192	Involved in chromosome partitioning
N5980_00900	COG0586	Pfam SNARE associated Golgi protein
N5980_00905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N5980_00905	COG0519	Catalyzes the synthesis of GMP from XMP
N5980_00910	COG3706	GGDEF domain
N5980_00915	COG3706	GGDEF domain
N5980_00960	COG2175	clavaminate synthase activity
N5980_00975	COG0534	Mate efflux family protein
N5980_00980	COG0436	Aminotransferase
N5980_01000	COG2837	iron assimilation
N5980_01015	COG1683	Conserved Protein
N5980_01020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N5980_01025	COG1121	(ABC) transporter
N5980_01075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N5980_01090	COG1012	belongs to the aldehyde dehydrogenase family
N5980_01105	COG0386	Belongs to the glutathione peroxidase family
N5980_01110	COG0386	Belongs to the glutathione peroxidase family
N5980_01115	COG0697	spore germination
N5980_01125	COG0758	DNA mediated transformation
N5980_01175	COG2814	Major facilitator Superfamily
N5980_01195	COG0477	Major facilitator Superfamily
N5980_01200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N5980_01205	COG3757	hydrolase, family 25
N5980_01225	COG1253	flavin adenine dinucleotide binding
N5980_01235	COG2860	membrane
N5980_01240	COG0477	Major facilitator Superfamily
N5980_01250	COG0318	PFAM AMP-dependent synthetase and ligase
N5980_01265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N5980_01300	COG2826	transposase and inactivated derivatives, IS30 family
N5980_01325	COG4372	Transposase
N5980_01385	COG0347	Belongs to the P(II) protein family
N5980_01390	COG0004	ammonium transporteR
N5980_01400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N5980_01400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N5980_01415	COG0586	Pfam SNARE associated Golgi protein
N5980_01435	COG0795	lipopolysaccharide-transporting ATPase activity
N5980_01440	COG0795	lipopolysaccharide-transporting ATPase activity
N5980_01445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N5980_01450	COG0793	Belongs to the peptidase S41A family
N5980_01450	COG3409	Peptidoglycan-binding domain 1 protein
N5980_01460	COG2205	protein histidine kinase activity
N5980_01465	COG2197	response regulator
N5980_01470	COG1686	Belongs to the peptidase S11 family
N5980_01480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N5980_01490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N5980_01495	COG4974	Belongs to the 'phage' integrase family
N5980_01520	COG0772	Belongs to the SEDS family
N5980_01530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N5980_01535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N5980_01540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N5980_01545	COG0494	nUDIX hydrolase
N5980_01560	COG1538	Outer membrane efflux protein
N5980_01570	COG1132	(ABC) transporter
N5980_01580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N5980_01615	COG0497	DNA recombination
N5980_01620	COG3123	guanosine phosphorylase activity
N5980_01625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N5980_01635	COG0237	dephospho-CoA kinase activity
N5980_01655	COG0149	triose-phosphate isomerase activity
N5980_01690	COG0779	Required for maturation of 30S ribosomal subunits
N5980_01695	COG0195	Participates in both transcription termination and antitermination
N5980_01705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N5980_01710	COG1320	monovalent cation:proton antiporter activity
N5980_01715	COG2212	antiporter activity
N5980_01720	COG1863	multisubunit Na H antiporter MnhE subunit
N5980_01725	COG0651	ATP synthesis coupled electron transport
N5980_01730	COG1006	Multisubunit Na H antiporter MnhC subunit
N5980_01735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N5980_01735	COG2111	Na H antiporter
N5980_01750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N5980_01755	COG4221	oxidoreductase activity
N5980_01765	COG0488	(ABC) transporter
N5980_01775	COG3293	Transposase
N5980_01840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N5980_01860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N5980_01865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N5980_01870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N5980_01875	COG2226	methyltransferase
N5980_01925	COG0067	glutamate synthase
N5980_01925	COG0069	glutamate synthase activity
N5980_01925	COG0070	glutamate synthase
N5980_01930	COG0493	'glutamate synthase
N5980_01935	COG1704	LemA family
N5980_01950	COG4969	Belongs to the N-Me-Phe pilin family
N5980_01965	COG3307	-O-antigen
N5980_01985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N5980_01990	COG1758	RNA polymerase activity
N5980_01995	COG0194	GDP metabolic process
N5980_02040	COG0228	four-way junction DNA binding
N5980_02045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N5980_02055	COG0335	large ribosomal subunit rRNA binding
N5980_02065	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N5980_02070	COG5380	lipid catabolic process
N5980_02075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N5980_02100	COG5006	permease, DMT superfamily
N5980_02105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N5980_02110	COG0277	FAD linked oxidase domain protein
N5980_02130	COG2814	Major facilitator Superfamily
N5980_02135	COG1289	transmembrane transporter activity
N5980_02145	COG0628	permease
N5980_02165	COG2226	methyltransferase
N5980_02180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N5980_02185	COG0254	rRNA binding
N5980_02190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N5980_02200	COG0534	Mate efflux family protein
N5980_02210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N5980_02220	COG1278	Cold shock
N5980_02225	COG1960	acyl-CoA dehydrogenase activity
N5980_02240	COG0408	coproporphyrinogen oxidase activity
N5980_02245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N5980_02255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N5980_02265	COG0513	Belongs to the DEAD box helicase family
N5980_02270	COG1127	ABC transporter
N5980_02275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N5980_02280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N5980_02285	COG2854	intermembrane phospholipid transfer
N5980_02295	COG0598	Magnesium transport protein CorA
N5980_02310	COG1040	competence protein
N5980_02315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N5980_02325	COG2937	Belongs to the GPAT DAPAT family
N5980_02330	COG1946	Acyl-CoA thioesterase
N5980_02335	COG1301	dicarboxylic acid transport
N5980_02355	COG1959	2 iron, 2 sulfur cluster binding
N5980_02370	COG0626	cystathionine gamma-synthase activity
N5980_02385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N5980_02390	COG0088	Forms part of the polypeptide exit tunnel
N5980_02405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N5980_02450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N5980_02455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N5980_02460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N5980_02470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N5980_02495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N5980_02505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N5980_02510	COG0202	RNA polymerase activity
N5980_02515	COG0203	ribosomal protein L17
N5980_02520	COG2072	flavoprotein involved in K transport
N5980_02525	COG1960	acyl-CoA dehydrogenase activity
N5980_02530	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N5980_02555	COG0697	spore germination
N5980_02565	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
N5980_02570	COG0339	signal peptide processing
N5980_02595	COG0557	exoribonuclease II activity
N5980_02635	COG0179	Fumarylacetoacetate (FAA) hydrolase
N5980_02645	COG1295	ribonuclease BN
N5980_02695	COG1702	phosphate starvation-inducible protein PhoH
N5980_02700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N5980_02705	COG0739	heme binding
N5980_02705	COG0741	lytic transglycosylase activity
N5980_02705	COG1196	nuclear chromosome segregation
N5980_02755	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N5980_02760	COG1183	phosphatidylcholine synthase activity
N5980_02820	COG1607	acyl-coa hydrolase
N5980_02850	COG2350	Protein conserved in bacteria
N5980_02865	COG3781	membrane
N5980_02870	COG2003	Belongs to the UPF0758 family
N5980_02875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N5980_02885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N5980_02945	COG1968	undecaprenyl-diphosphatase activity
N5980_02950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N5980_02955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N5980_02965	COG2205	protein histidine kinase activity
N5980_02970	COG0745	RESPONSE REGULATOR receiver
N5980_02985	COG0174	glutamine synthetase
N5980_03000	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N5980_03010	COG0732	type I restriction modification DNA specificity domain
N5980_03025	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N5980_03055	COG2814	Major facilitator Superfamily
N5980_03080	COG3622	Belongs to the hyi family
N5980_03085	COG2084	Dehydrogenase
N5980_03090	COG1024	Enoyl-CoA hydratase
N5980_03095	COG0784	Response regulator, receiver
N5980_03095	COG2205	protein histidine kinase activity
N5980_03095	COG5002	protein histidine kinase activity
N5980_03100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N5980_03115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N5980_03125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N5980_03135	COG1862	Preprotein translocase
N5980_03150	COG1704	LemA family
N5980_03160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N5980_03170	COG0318	PFAM AMP-dependent synthetase and ligase
N5980_03215	COG0625	glutathione transferase activity
N5980_03225	COG1238	metal cluster binding
N5980_03260	COG0072	phenylalanine-tRNA ligase activity
N5980_03285	COG0248	Ppx GppA phosphatase
N5980_03295	COG0037	tRNA processing
N5980_03335	COG1764	response to oxidative stress
N5980_03340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N5980_03415	COG2969	positive regulation of protein catabolic process
N5980_03420	COG0625	glutathione transferase activity
N5980_03425	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N5980_03430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N5980_03435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N5980_03440	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N5980_03445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N5980_03475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N5980_03485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N5980_03490	COG1408	metallophosphoesterase
N5980_03500	COG0477	Major facilitator Superfamily
N5980_03505	COG1272	protein, Hemolysin III
N5980_03525	COG1024	Enoyl-CoA hydratase
N5980_03525	COG1250	3-hydroxyacyl-CoA dehydrogenase
N5980_03530	COG0183	Belongs to the thiolase family
N5980_03535	COG2207	Transcriptional regulator
N5980_03540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N5980_03545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N5980_03560	COG0183	Belongs to the thiolase family
N5980_03580	COG0833	amino acid
N5980_03590	COG2233	PERMEase
N5980_03595	COG1217	gtp-binding protein TYPA
N5980_03620	COG1902	pentaerythritol trinitrate reductase activity
N5980_03635	COG0354	folic acid binding
N5980_03640	COG2132	Multicopper oxidase
N5980_03645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N5980_03655	COG4372	Transposase
N5980_03715	COG0564	pseudouridine synthase activity
N5980_03745	COG2824	Alkylphosphonate utilization operon protein PhnA
N5980_03770	COG0351	phosphomethylpyrimidine kinase
N5980_03770	COG0352	thiamine-phosphate diphosphorylase activity
N5980_03770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N5980_03805	COG3152	Membrane
N5980_03815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N5980_03830	COG0745	RESPONSE REGULATOR receiver
N5980_03835	COG2205	protein histidine kinase activity
N5980_03845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N5980_03865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N5980_03880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N5980_03885	COG0839	Belongs to the complex I subunit 6 family
N5980_03890	COG0713	ATP synthesis coupled electron transport
N5980_03895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N5980_03900	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N5980_03925	COG1278	Cold shock
N5980_03930	COG0583	DNA-binding transcription factor activity
N5980_03950	COG0668	transmembrane transport
N5980_03965	COG2081	HI0933 family
N5980_03990	COG0004	ammonium transporteR
N5980_03995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N5980_04005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N5980_04005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N5980_04015	COG0489	protein tyrosine kinase activity
N5980_04030	COG2358	TRAP transporter, solute receptor (TAXI family
N5980_04100	COG0840	transmembrane signaling receptor activity
N5980_04130	COG2832	Protein of unknown function (DUF454)
N5980_04190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N5980_04200	COG1289	transmembrane transporter activity
N5980_04205	COG2814	Major facilitator Superfamily
N5980_04215	COG0786	glutamate:sodium symporter activity
N5980_04220	COG1115	amino acid carrier protein
N5980_04225	COG2059	Chromate
N5980_04230	COG1752	Esterase of the alpha-beta hydrolase superfamily
N5980_04240	COG1607	acyl-coa hydrolase
N5980_04260	COG0625	glutathione transferase activity
N5980_04275	COG0523	cobalamin synthesis protein
N5980_04285	COG1285	pathogenesis
N5980_04295	COG2203	Gaf domain
N5980_04295	COG2199	diguanylate cyclase activity
N5980_04340	COG0393	Putative heavy-metal-binding
N5980_04345	COG0393	Putative heavy-metal-binding
N5980_04350	COG1538	Outer membrane efflux protein
N5980_04360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5980_04365	COG0671	phosphoesterase, PA-phosphatase related
N5980_04380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N5980_04390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N5980_04400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N5980_04405	COG1648	precorrin-2 dehydrogenase activity
N5980_04405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N5980_04410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N5980_04420	COG0531	amino acid
N5980_04435	COG0321	lipoyl(octanoyl) transferase activity
N5980_04445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N5980_04465	COG0586	Pfam SNARE associated Golgi protein
N5980_04490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N5980_04520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N5980_04550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N5980_04560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N5980_04565	COG0358	DNA primase activity
N5980_04575	COG0564	pseudouridine synthase activity
N5980_04600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N5980_04620	COG0110	maltose O-acetyltransferase activity
N5980_04625	COG0251	oxidation-reduction process
N5980_04630	COG1309	transcriptional regulator
N5980_04640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N5980_04645	COG0505	Belongs to the CarA family
N5980_04670	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N5980_04675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N5980_04685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N5980_04720	COG1253	flavin adenine dinucleotide binding
N5980_04740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N5980_04750	COG2239	Acts as a magnesium transporter
N5980_04760	COG0501	Belongs to the peptidase M48B family
N5980_04765	COG0739	heme binding
N5980_04765	COG0741	lytic transglycosylase activity
N5980_04765	COG1196	nuclear chromosome segregation
N5980_04770	COG0037	tRNA processing
N5980_04785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N5980_04800	COG0583	DNA-binding transcription factor activity
N5980_04805	COG1960	acyl-CoA dehydrogenase activity
N5980_04810	COG2814	Major facilitator Superfamily
N5980_04825	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N5980_04850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N5980_04855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N5980_04860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N5980_04885	COG1115	amino acid carrier protein
N5980_04890	COG1113	amino acid transport
N5980_04915	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N5980_04925	COG1522	sequence-specific DNA binding
N5980_04930	COG1280	lysine exporter protein (LysE YggA)
N5980_04970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5980_04990	COG1671	Belongs to the UPF0178 family
N5980_05010	COG1136	(ABC) transporter
N5980_05015	COG0658	competence protein
N5980_05015	COG2333	competence protein COMEC
N5980_05030	COG2267	carboxylic ester hydrolase activity
N5980_05035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N5980_05040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N5980_05045	COG0628	permease
N5980_05050	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N5980_05080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N5980_05100	COG0823	Involved in the tonB-independent uptake of proteins
N5980_05120	COG0824	Thioesterase
N5980_05125	COG1473	amidohydrolase
N5980_05130	COG2255	four-way junction helicase activity
N5980_05155	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N5980_05155	COG0047	phosphoribosylformylglycinamidine synthase activity
N5980_05170	COG0583	DNA-binding transcription factor activity
N5980_05190	COG1024	Enoyl-CoA hydratase
N5980_05195	COG1056	cytidyltransferase-related domain
N5980_05195	COG1051	belongs to the nudix hydrolase family
N5980_05200	COG2353	YceI-like domain
N5980_05205	COG0583	DNA-binding transcription factor activity
N5980_05210	COG1279	arginine transmembrane transporter activity
N5980_05215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N5980_05225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N5980_05230	COG0602	queuosine metabolic process
N5980_05250	COG0583	DNA-binding transcription factor activity
N5980_05255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N5980_05260	COG4208	sulfate ABC transporter
N5980_05265	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N5980_05275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N5980_05280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N5980_05290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N5980_05310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N5980_05335	COG0571	ribonuclease III activity
N5980_05340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N5980_05350	COG1381	Involved in DNA repair and RecF pathway recombination
N5980_05355	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N5980_05365	COG3293	Transposase
N5980_05395	COG0436	Aminotransferase
N5980_05405	COG0052	Belongs to the universal ribosomal protein uS2 family
N5980_05430	COG2951	lytic endotransglycosylase activity
N5980_05445	COG0842	Transport permease protein
N5980_05450	COG1131	(ABC) transporter
N5980_05505	COG2862	Uncharacterized protein family, UPF0114
N5980_05525	COG3634	alkyl hydroperoxide reductase activity
N5980_05530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N5980_05535	COG0826	peptidase U32
N5980_05560	COG4993	Dehydrogenase
N5980_05570	COG1720	tRNA m6t6A37 methyltransferase activity
N5980_05585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N5980_05600	COG0642	Histidine kinase
N5980_05610	COG0352	thiamine-phosphate diphosphorylase activity
N5980_05620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N5980_05625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N5980_05630	COG3139	Protein of unknown function (DUF1315)
N5980_05640	COG1301	dicarboxylic acid transport
N5980_05645	COG1960	acyl-CoA dehydrogenase activity
N5980_05650	COG0693	protein deglycase activity
N5980_05660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N5980_05665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N5980_05695	COG2252	PERMEase
N5980_05700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N5980_05715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N5980_05725	COG0527	aspartate kinase activity
N5980_05730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N5980_05735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N5980_05760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N5980_05765	COG0501	Belongs to the peptidase M48B family
N5980_05785	COG1252	NADH dehydrogenase
N5980_05790	COG1686	Belongs to the peptidase S11 family
N5980_05805	COG2351	hydroxyisourate hydrolase activity
N5980_05825	COG1187	pseudouridine synthase activity
N5980_05850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N5980_05850	COG2755	lipolytic protein G-D-S-L family
N5980_05860	COG0436	Aminotransferase
N5980_05865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N5980_05870	COG0386	Belongs to the glutathione peroxidase family
N5980_05880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N5980_05895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N5980_05905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N5980_05910	COG0012	GTP binding
N5980_05915	COG2011	ABC-type metal ion transport system permease component
N5980_05920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N5980_05925	COG1464	Belongs to the NlpA lipoprotein family
N5980_06020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N5980_06020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N5980_06025	COG1254	Belongs to the acylphosphatase family
N5980_06060	COG3634	alkyl hydroperoxide reductase activity
N5980_06085	COG1643	Atp-dependent helicase
N5980_06105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N5980_06110	COG2707	UPF0756 membrane protein
N5980_06135	COG0802	atpase or kinase
N5980_06140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N5980_06150	COG1923	regulation of RNA biosynthetic process
N5980_06160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N5980_06170	COG3178	'Phosphotransferase
N5980_06175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N5980_06185	COG1192	Involved in chromosome partitioning
N5980_06190	COG1475	DNA binding
N5980_06195	COG0811	peptide transport
N5980_06205	COG1132	(ABC) transporter
N5980_06210	COG1663	tetraacyldisaccharide 4'-kinase activity
N5980_06230	COG0084	hydrolase, TatD family'
N5980_06235	COG1309	transcriptional regulator
N5980_06265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N5980_06295	COG0776	regulation of translation
N5980_06315	COG2431	L-lysine efflux transmembrane transporter activity
N5980_06330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N5980_06335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N5980_06355	COG1253	flavin adenine dinucleotide binding
N5980_06360	COG3293	Transposase
N5980_06365	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N5980_06380	COG0308	aminopeptidase N
N5980_06390	COG0589	response to stress
N5980_06395	COG0589	response to stress
N5980_06405	COG3293	Transposase
N5980_06415	COG3135	benzoate transporter
N5980_06425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N5980_06440	COG0183	Belongs to the thiolase family
N5980_06470	COG0824	Thioesterase
N5980_06475	COG1454	alcohol dehydrogenase
N5980_06480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N5980_06500	COG0069	glutamate synthase activity
N5980_06510	COG2308	Evidence 4 Homologs of previously reported genes of
N5980_06520	COG1305	Transglutaminase-like
N5980_06535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N5980_06540	COG0305	Participates in initiation and elongation during chromosome replication
N5980_06555	COG0360	Binds together with S18 to 16S ribosomal RNA
N5980_06565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N5980_06570	COG1845	cytochrome c oxidase, subunit III
N5980_06575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N5980_06580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N5980_06605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N5980_06620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N5980_06625	COG2890	protein-(glutamine-N5) methyltransferase activity
N5980_06630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N5980_06635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N5980_06660	COG1960	acyl-CoA dehydrogenase activity
N5980_06665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N5980_06680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N5980_06690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N5980_06710	COG0477	Major facilitator Superfamily
N5980_06715	COG0729	surface antigen
N5980_06730	COG1570	exodeoxyribonuclease VII activity
N5980_06770	COG4372	Transposase
N5980_06885	COG0305	Participates in initiation and elongation during chromosome replication
N5980_06905	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N5980_06965	COG5410	chromosome segregation
N5980_07025	COG3561	AntA/AntB antirepressor
N5980_07155	COG0024	Methionine aminopeptidase
N5980_07160	COG0583	DNA-binding transcription factor activity
N5980_07165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N5980_07180	COG1902	pentaerythritol trinitrate reductase activity
N5980_07180	COG0446	pyridine nucleotide-disulphide oxidoreductase
N5980_07210	COG0148	phosphopyruvate hydratase activity
N5980_07225	COG0772	Belongs to the SEDS family
N5980_07240	COG4890	Cyd operon protein YbgT
N5980_07245	COG1294	oxidase, subunit
N5980_07295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N5980_07315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N5980_07325	COG0133	tryptophan synthase activity
N5980_07330	COG0516	GMP reductase activity
N5980_07330	COG0517	IMP dehydrogenase activity
N5980_07360	COG0612	Peptidase, M16
N5980_07365	COG0552	protein localization to endoplasmic reticulum
N5980_07425	COG1960	acyl-CoA dehydrogenase activity
N5980_07495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N5980_07500	COG0730	response to heat
N5980_07505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N5980_07510	COG2207	Transcriptional regulator
N5980_07530	COG1960	acyl-CoA dehydrogenase activity
N5980_07555	COG1271	oxidase subunit
N5980_07560	COG1294	oxidase, subunit
N5980_07570	COG1525	nuclease
N5980_07625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N5980_07640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N5980_07660	COG0509	glycine decarboxylation via glycine cleavage system
N5980_07670	COG1132	(ABC) transporter
N5980_07675	COG0668	transmembrane transport
N5980_07685	COG3122	Protein conserved in bacteria
N5980_07710	COG0640	Transcriptional regulator
N5980_07715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N5980_07725	COG0789	Transcriptional regulator
N5980_07740	COG1960	acyl-CoA dehydrogenase activity
N5980_07745	COG0183	Belongs to the thiolase family
N5980_07765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N5980_07770	COG0183	Belongs to the thiolase family
N5980_07775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N5980_07780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N5980_07785	COG3135	benzoate transporter
N5980_07790	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_07795	COG0633	Ferredoxin
N5980_07795	COG0543	2 iron, 2 sulfur cluster binding
N5980_07800	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
N5980_07805	COG4638	Rieske (2fe-2S)
N5980_07815	COG4829	muconolactone delta-isomerase
N5980_07820	COG4948	Mandelate Racemase Muconate Lactonizing
N5980_07825	COG0583	DNA-binding transcription factor activity
N5980_07830	COG2814	Major facilitator Superfamily
N5980_07840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N5980_07850	COG0318	PFAM AMP-dependent synthetase and ligase
N5980_07870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N5980_07875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N5980_07880	COG1116	anion transmembrane transporter activity
N5980_07880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N5980_07905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N5980_07910	COG1309	transcriptional regulator
N5980_07930	COG1944	ATP diphosphatase activity
N5980_07940	COG1960	acyl-CoA dehydrogenase activity
N5980_07945	COG1960	acyl-CoA dehydrogenase activity
N5980_07950	COG2814	Major facilitator Superfamily
N5980_07960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N5980_07965	COG2814	Major facilitator Superfamily
N5980_07975	COG2814	Major facilitator Superfamily
N5980_07985	COG1250	3-hydroxyacyl-CoA dehydrogenase
N5980_07990	COG0183	Belongs to the thiolase family
N5980_08000	COG0235	Class ii aldolase
N5980_08005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N5980_08010	COG1024	Enoyl-CoA hydratase
N5980_08020	COG1960	acyl-CoA dehydrogenase activity
N5980_08025	COG2267	carboxylic ester hydrolase activity
N5980_08040	COG0318	PFAM AMP-dependent synthetase and ligase
N5980_08055	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_08065	COG0640	Transcriptional regulator
N5980_08090	COG2132	Multicopper oxidase
N5980_08115	COG4773	Receptor
N5980_08125	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
N5980_08130	COG2116	formate transmembrane transporter activity
N5980_08135	COG0515	serine threonine protein kinase
N5980_08170	COG0583	DNA-binding transcription factor activity
N5980_08180	COG1289	transmembrane transporter activity
N5980_08210	COG2801	Transposase and inactivated derivatives
N5980_08215	COG4772	TonB-dependent receptor
N5980_08240	COG1079	Belongs to the binding-protein-dependent transport system permease family
N5980_08250	COG3845	ABC transporter
N5980_08270	COG0583	DNA-binding transcription factor activity
N5980_08280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5980_08285	COG4266	Belongs to the allantoicase family
N5980_08300	COG2233	PERMEase
N5980_08305	COG2351	hydroxyisourate hydrolase activity
N5980_08325	COG0804	urea catabolic process
N5980_08340	COG0829	nickel cation binding
N5980_08355	COG0830	nickel cation binding
N5980_08395	COG0596	Alpha beta hydrolase
N5980_08435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N5980_08470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N5980_08485	COG0439	Biotin carboxylase
N5980_08495	COG3706	GGDEF domain
N5980_08520	COG4372	Transposase
N5980_08560	COG5499	transcription regulator containing HTH domain
N5980_08565	COG4680	protein conserved in bacteria
N5980_08600	COG1058	Belongs to the CinA family
N5980_08600	COG1546	Belongs to the CinA family
N5980_08610	COG0372	Belongs to the citrate synthase family
N5980_08640	COG0542	response to heat
N5980_08645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N5980_08665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N5980_08670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N5980_08675	COG0569	domain protein
N5980_08680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N5980_08700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N5980_08710	COG1585	Membrane protein implicated in regulation of membrane protease activity
N5980_08730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N5980_08750	COG1959	2 iron, 2 sulfur cluster binding
N5980_08760	COG0822	iron-sulfur transferase activity
N5980_08765	COG0316	Belongs to the HesB IscA family
N5980_08795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N5980_08805	COG1027	Aspartate ammonia-lyase
N5980_08820	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N5980_08820	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N5980_08820	COG0506	proline dehydrogenase activity
N5980_08840	COG3781	membrane
N5980_08845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N5980_08880	COG0697	spore germination
N5980_08905	COG0424	maF-like protein
N5980_08910	COG2850	peptidyl-arginine hydroxylation
N5980_08915	COG4585	Histidine kinase
N5980_08930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N5980_08935	COG0702	epimerase
N5980_08940	COG0268	Binds directly to 16S ribosomal RNA
N5980_08960	COG1011	Hydrolase
N5980_08965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N5980_08975	COG2137	regulation of response to DNA damage stimulus
N5980_08990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N5980_08995	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N5980_09010	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N5980_09025	COG0575	Belongs to the CDS family
N5980_09030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N5980_09050	COG3852	Histidine kinase
N5980_09065	COG0445	tRNA wobble uridine modification
N5980_09095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N5980_09100	COG0138	bifunctional purine biosynthesis protein purh
N5980_09115	COG1464	Belongs to the NlpA lipoprotein family
N5980_09120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N5980_09125	COG2011	ABC-type metal ion transport system permease component
N5980_09160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N5980_09170	COG4122	O-methyltransferase activity
N5980_09205	COG1137	ATPase activity
N5980_09210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N5980_09220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
N5980_09225	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N5980_09225	COG0517	IMP dehydrogenase activity
N5980_09275	COG0505	Belongs to the CarA family
N5980_09295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N5980_09315	COG2391	methyltransferase activity
N5980_09345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N5980_09375	COG2267	carboxylic ester hydrolase activity
N5980_09405	COG2826	transposase and inactivated derivatives, IS30 family
N5980_09420	COG0352	thiamine-phosphate diphosphorylase activity
N5980_09435	COG3025	triphosphatase activity
N5980_09455	COG0612	Peptidase, M16
N5980_09470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N5980_09555	COG1610	YqeY-like protein
N5980_09570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N5980_09620	COG0778	Nitroreductase
N5980_09630	COG0513	Belongs to the DEAD box helicase family
N5980_09650	COG2363	Small membrane protein
N5980_09675	COG2249	NAD(P)H dehydrogenase (quinone) activity
N5980_09685	COG0659	secondary active sulfate transmembrane transporter activity
N5980_09690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N5980_09710	COG0318	PFAM AMP-dependent synthetase and ligase
N5980_09715	COG1309	transcriptional regulator
N5980_09720	COG1960	acyl-CoA dehydrogenase activity
N5980_09725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N5980_09730	COG1024	Enoyl-CoA hydratase
N5980_09735	COG4770	biotin carboxylase activity
N5980_09750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N5980_09770	COG0540	Belongs to the ATCase OTCase family
N5980_09795	COG0667	Aldo Keto reductase
N5980_09805	COG1765	OsmC-like protein
N5980_09810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N5980_09820	COG3293	Transposase
N5980_09840	COG0714	Associated with various cellular activities
N5980_09845	COG2879	small protein
N5980_09850	COG1966	Carbon starvation protein
N5980_09855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N5980_09895	COG1067	ATP-dependent peptidase activity
N5980_09900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N5980_09905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N5980_09910	COG0583	DNA-binding transcription factor activity
N5980_09935	COG1686	Belongs to the peptidase S11 family
N5980_09940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N5980_09955	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N5980_09955	COG2755	lipolytic protein G-D-S-L family
N5980_09965	COG0482	sulfurtransferase activity
N5980_09995	COG0616	signal peptide processing
N5980_10005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N5980_10015	COG0573	inorganic phosphate transmembrane transporter activity
N5980_10020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N5980_10025	COG1113	amino acid transport
N5980_10030	COG3961	Belongs to the TPP enzyme family
N5980_10035	COG1522	sequence-specific DNA binding
N5980_10040	COG1012	belongs to the aldehyde dehydrogenase family
N5980_10050	COG0076	glutamate decarboxylase activity
N5980_10055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N5980_10065	COG0671	phosphoesterase, PA-phosphatase related
N5980_10090	COG1733	regulation of RNA biosynthetic process
N5980_10105	COG3040	lipid binding
N5980_10110	COG0556	nucleotide-excision repair
N5980_10155	COG2721	sulfolactate sulfo-lyase activity
N5980_10175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N5980_10180	COG1960	acyl-CoA dehydrogenase activity
N5980_10190	COG2084	Dehydrogenase
N5980_10195	COG2233	PERMEase
N5980_10200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N5980_10205	COG0251	oxidation-reduction process
N5980_10210	COG1335	isochorismatase
N5980_10215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N5980_10220	COG0596	Alpha beta hydrolase
N5980_10230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N5980_10235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N5980_10240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N5980_10280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N5980_10295	COG0174	glutamine synthetase
N5980_10300	COG3293	Transposase
N5980_10305	COG0512	Glutamine amidotransferase of anthranilate synthase
N5980_10310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N5980_10330	COG0302	gtp cyclohydrolase
N5980_10345	COG3706	GGDEF domain
N5980_10360	COG3739	integral membrane protein
N5980_10375	COG1741	Belongs to the pirin family
N5980_10395	COG1546	Belongs to the CinA family
N5980_10395	COG1058	Belongs to the CinA family
N5980_10415	COG0281	malic enzyme
N5980_10460	COG1785	Belongs to the alkaline phosphatase family
N5980_10465	COG1785	Belongs to the alkaline phosphatase family
N5980_10485	COG0446	pyridine nucleotide-disulphide oxidoreductase
N5980_10485	COG1902	pentaerythritol trinitrate reductase activity
N5980_10500	COG3706	GGDEF domain
N5980_10505	COG0418	dihydroorotase activity
N5980_10510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N5980_10525	COG0833	amino acid
N5980_10535	COG0833	amino acid
N5980_10575	COG4239	(ABC) transporter, permease
N5980_10580	COG4174	ABC transporter (Permease)
N5980_10585	COG4166	transmembrane transport
N5980_10590	COG0741	lytic transglycosylase activity
N5980_10590	COG1388	LysM domain
N5980_10605	COG2816	NAD+ diphosphatase activity
N5980_10610	COG0657	acetylesterase activity
N5980_10625	COG3107	peptidoglycan biosynthetic process
N5980_10640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5980_10645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N5980_10655	COG2826	transposase and inactivated derivatives, IS30 family
N5980_10660	COG3293	Transposase
N5980_10665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N5980_10670	COG2155	Conserved Protein
N5980_10675	COG0006	proline dipeptidase activity
N5980_10700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N5980_10710	COG2234	aminopeptidase activity
N5980_10715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N5980_10720	COG3384	dioxygenase
N5980_10730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N5980_10735	COG2878	Part of a membrane complex involved in electron transport
N5980_10740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N5980_10765	COG0768	penicillin binding
N5980_10770	COG0742	ribosomal rna small subunit methyltransferase
N5980_10785	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_10815	COG0459	protein refolding
N5980_10830	COG1597	lipid kinase activity
N5980_10840	COG0477	Major facilitator Superfamily
N5980_10855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N5980_10880	COG0604	alcohol dehydrogenase
N5980_10880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N5980_10880	COG3321	synthase
N5980_10880	COG4221	oxidoreductase activity
N5980_10890	COG3118	belongs to the thioredoxin family
N5980_10940	COG2268	Band 7 protein
N5980_10945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N5980_10955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N5980_10970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N5980_10975	COG1053	succinate dehydrogenase
N5980_10980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N5980_11000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N5980_11000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N5980_11015	COG2826	transposase and inactivated derivatives, IS30 family
N5980_11020	COG0589	response to stress
N5980_11040	COG2321	neutral zinc metallopeptidase
N5980_11045	COG2354	Protein conserved in bacteria
N5980_11075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N5980_11080	COG1773	rubredoxin
N5980_11085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N5980_11095	COG0583	DNA-binding transcription factor activity
N5980_11110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N5980_11120	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
N5980_11125	COG4181	ATPase activity
N5980_11150	COG4771	TonB-dependent receptor
N5980_11165	COG4607	ABC-type enterochelin transport system periplasmic component
N5980_11175	COG0306	phosphate transporter
N5980_11200	COG2376	Dihydroxyacetone kinase
N5980_11205	COG2066	Belongs to the glutaminase family
N5980_11210	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_11220	COG0525	valine-tRNA ligase activity
N5980_11235	COG3293	Transposase
N5980_11255	COG2323	membrane
N5980_11260	COG0546	phosphoglycolate phosphatase activity
N5980_11280	COG1752	Esterase of the alpha-beta hydrolase superfamily
N5980_11295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N5980_11300	COG0142	geranyltranstransferase activity
N5980_11305	COG2828	Protein conserved in bacteria
N5980_11310	COG1113	amino acid transport
N5980_11330	COG0560	Phosphoserine phosphatase
N5980_11340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N5980_11355	COG0424	maF-like protein
N5980_11360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N5980_11365	COG1792	Involved in formation and maintenance of cell shape
N5980_11370	COG1077	Cell shape determining protein MreB Mrl
N5980_11375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N5980_11385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N5980_11420	COG0697	spore germination
N5980_11430	COG3590	peptidase
N5980_11435	COG3590	peptidase
N5980_11445	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N5980_11460	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N5980_11465	COG2223	nitrite transmembrane transporter activity
N5980_11475	COG0500	methyltransferase
N5980_11500	COG0783	Belongs to the Dps family
N5980_11520	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N5980_11525	COG4149	molybdate abc transporter
N5980_11530	COG0725	ABC transporter, periplasmic molybdate-binding protein
N5980_11535	COG0303	'Molybdopterin
N5980_11540	COG0315	cyclic pyranopterin monophosphate synthase activity
N5980_11540	COG0521	Mo-molybdopterin cofactor biosynthetic process
N5980_11545	COG0314	molybdopterin synthase activity
N5980_11555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N5980_11565	COG0243	molybdopterin cofactor binding
N5980_11570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N5980_11575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N5980_11580	COG2223	nitrite transmembrane transporter activity
N5980_11595	COG0583	DNA-binding transcription factor activity
N5980_11610	COG0402	S-adenosylhomocysteine deaminase activity
N5980_11620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N5980_11655	COG4372	Transposase
N5980_11690	COG0582	viral genome integration into host DNA
N5980_11700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N5980_11705	COG2814	Major facilitator Superfamily
N5980_11710	COG1566	PFAM secretion protein HlyD family protein
N5980_11715	COG3293	Transposase
N5980_11720	COG2050	protein possibly involved in aromatic compounds catabolism
N5980_11730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N5980_11735	COG1090	epimerase
N5980_11745	COG0420	3'-5' exonuclease activity
N5980_11775	COG0735	belongs to the Fur family
N5980_11780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N5980_11785	COG2914	Belongs to the UPF0125 (RnfH) family
N5980_11800	COG0121	glutamine amidotransferase
N5980_11815	COG0756	dUTP diphosphatase activity
N5980_11825	COG2885	chlorophyll binding
N5980_11830	COG0204	Acyl-transferase
N5980_11840	COG0850	regulation of cytokinetic process
N5980_11845	COG2894	cell division
N5980_11860	COG0531	amino acid
N5980_11860	COG1674	ftsk spoiiie
N5980_11865	COG0492	ferredoxin-NADP+ reductase activity
N5980_11870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N5980_11880	COG0456	acetyltransferase
N5980_11905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N5980_11920	COG1981	membrane
N5980_11925	COG1113	amino acid transport
N5980_11930	COG0251	oxidation-reduction process
N5980_11950	COG1652	LysM domain
N5980_11955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N5980_11960	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_11970	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N5980_11975	COG1399	metal-binding, possibly nucleic acid-binding protein
N5980_11980	COG3101	peptidyl-lysine hydroxylation
N5980_11985	COG0009	L-threonylcarbamoyladenylate synthase
N5980_12000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N5980_12005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N5980_12030	COG0339	signal peptide processing
N5980_12040	COG4166	transmembrane transport
N5980_12050	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
N5980_12070	COG2193	ferroxidase activity
N5980_12075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N5980_12080	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
N5980_12085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N5980_12095	COG1196	nuclear chromosome segregation
N5980_12105	COG0730	response to heat
N5980_12120	COG3545	Serine hydrolase
N5980_12130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N5980_12150	COG3327	negative regulation of DNA-templated transcription, initiation
N5980_12155	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
N5980_12180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N5980_12190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N5980_12210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N5980_12225	COG1968	undecaprenyl-diphosphatase activity
N5980_12230	COG1214	PFAM Peptidase M22, glycoprotease
N5980_12240	COG0494	nUDIX hydrolase
N5980_12295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N5980_12305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N5980_12390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N5980_12395	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N5980_12435	COG0285	dihydrofolate synthase activity
N5980_12480	COG4206	TonB-dependent receptor
N5980_12485	COG2096	Adenosyltransferase
N5980_12500	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N5980_12520	COG1113	amino acid transport
N5980_12530	COG0745	RESPONSE REGULATOR receiver
N5980_12535	COG2205	protein histidine kinase activity
N5980_12550	COG1960	acyl-CoA dehydrogenase activity
N5980_12555	COG1960	acyl-CoA dehydrogenase activity
N5980_12600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N5980_12660	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N5980_12665	COG2205	protein histidine kinase activity
N5980_12680	COG1660	Displays ATPase and GTPase activities
N5980_12695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N5980_12700	COG0617	tRNA 3'-terminal CCA addition
N5980_12705	COG1596	polysaccharide export
N5980_12705	COG1555	photosystem II stabilization
N5980_12710	COG3956	TIGRFAM MazG family protein
N5980_12750	COG0124	histidyl-tRNA synthetase
N5980_12760	COG1426	Protein conserved in bacteria
N5980_12780	COG2975	iron-sulfur cluster assembly
N5980_12800	COG0028	Belongs to the TPP enzyme family
N5980_12830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5980_12835	COG0577	efflux transmembrane transporter activity
N5980_12835	COG1136	(ABC) transporter
N5980_12840	COG1538	Outer membrane efflux protein
N5980_12855	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N5980_12865	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N5980_12870	COG1162	GTPase activity
N5980_12900	COG0084	hydrolase, TatD family'
N5980_12915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N5980_12945	COG4251	negative regulation of phosphorylation
N5980_12945	COG3706	GGDEF domain
N5980_12945	COG5001	Diguanylate cyclase
N5980_12945	COG2203	Gaf domain
N5980_12990	COG0793	Belongs to the peptidase S41A family
N5980_13015	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N5980_13020	COG0857	belongs to the CobB CobQ family
N5980_13020	COG0280	phosphate acetyltransferase
N5980_13030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
N5980_13030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
N5980_13045	COG0740	serine-type endopeptidase activity
N5980_13055	COG4774	siderophore transport
N5980_13065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N5980_13070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N5980_13075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N5980_13075	COG2813	Specifically methylates the guanine in position
N5980_13125	COG3040	lipid binding
N5980_13135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N5980_13155	COG4372	Transposase
N5980_13190	COG0210	DNA helicase
N5980_13230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N5980_13360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N5980_13395	COG0788	formyltetrahydrofolate deformylase activity
N5980_13420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N5980_13420	COG4651	solute:proton antiporter activity
N5980_13435	COG0724	RNA recognition motif
N5980_13440	COG0210	DNA helicase
N5980_13445	COG1929	Belongs to the glycerate kinase type-1 family
N5980_13485	COG2900	Belongs to the SlyX family
N5980_13490	COG0488	(ABC) transporter
N5980_13495	COG1560	Kdo2-lipid A biosynthetic process
N5980_13560	COG0473	3-isopropylmalate dehydrogenase activity
N5980_13575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N5980_13625	COG0753	catalase activity
N5980_13655	COG0519	Catalyzes the synthesis of GMP from XMP
N5980_13665	COG0446	pyridine nucleotide-disulphide oxidoreductase
N5980_13670	COG3384	dioxygenase
N5980_13675	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_13690	COG4638	Rieske (2fe-2S)
N5980_13695	COG0583	DNA-binding transcription factor activity
N5980_13715	COG4569	acetaldehyde dehydrogenase (acetylating) activity
N5980_13720	COG3971	2-oxopent-4-enoate hydratase activity
N5980_13725	COG0546	phosphoglycolate phosphatase activity
N5980_13740	COG1530	ribonuclease E activity
N5980_13745	COG0318	PFAM AMP-dependent synthetase and ligase
N5980_13770	COG1983	PspC domain protein
N5980_13780	COG0471	metal ion transport
N5980_13785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N5980_13785	COG0617	tRNA 3'-terminal CCA addition
N5980_13785	COG0517	IMP dehydrogenase activity
N5980_13795	COG0752	glycyl-tRNA synthetase alpha subunit
N5980_13800	COG0751	glycine-tRNA ligase activity
N5980_13835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N5980_13865	COG0644	oxidoreductase
N5980_13875	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N5980_13885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N5980_13900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N5980_13910	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
N5980_13910	COG0644	oxidoreductase
N5980_13940	COG0425	Belongs to the sulfur carrier protein TusA family
N5980_13945	COG4535	Mg2 and Co2 transporter CorC
N5980_13970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N5980_13980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N5980_14005	COG0789	Transcriptional regulator
N5980_14010	COG2841	Protein conserved in bacteria
N5980_14020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N5980_14025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N5980_14030	COG1074	ATP-dependent DNA helicase activity
N5980_14035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N5980_14055	COG2226	methyltransferase
N5980_14065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N5980_14095	COG0427	acetyl-CoA hydrolase
N5980_14100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N5980_14140	COG0326	Molecular chaperone. Has ATPase activity
N5980_14150	COG3047	cAMP biosynthetic process
N5980_14155	COG2056	Na+-H+ antiporter family
N5980_14175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N5980_14180	COG0085	RNA polymerase activity
N5980_14195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N5980_14255	COG0546	phosphoglycolate phosphatase activity
N5980_14285	COG0824	Thioesterase
N5980_14305	COG0181	hydroxymethylbilane synthase activity
N5980_14315	COG3275	phosphorelay sensor kinase activity
N5980_14330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N5980_14360	COG1024	Enoyl-CoA hydratase
N5980_14360	COG1250	3-hydroxyacyl-CoA dehydrogenase
N5980_14365	COG0183	Belongs to the thiolase family
N5980_14425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N5980_14455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N5980_14495	COG3158	transport of potassium into the cell
N5980_14550	COG0629	single-stranded DNA binding
N5980_14555	COG2814	Major facilitator Superfamily
N5980_14570	COG0351	phosphomethylpyrimidine kinase
N5980_14570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N5980_14570	COG0352	thiamine-phosphate diphosphorylase activity
N5980_14585	COG3706	GGDEF domain
N5980_14590	COG0675	Transposase, IS605 OrfB family
N5980_14605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N5980_14615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N5980_14620	COG3162	membrane
N5980_14625	COG2205	protein histidine kinase activity
N5980_14625	COG2198	Histidine kinase
N5980_14625	COG0784	Response regulator, receiver
N5980_14640	COG0431	NADPH-dependent FMN reductase
N5980_14650	COG0307	riboflavin synthase, alpha
N5980_14665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N5980_14675	COG0668	transmembrane transport
N5980_14680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N5980_14685	COG1519	Transferase
N5980_14690	COG1902	pentaerythritol trinitrate reductase activity
N5980_14715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N5980_14740	COG0426	domain, Protein
N5980_14740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N5980_14745	COG2119	membrane
N5980_14775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N5980_14785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N5980_14795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N5980_14810	COG0189	ligase activity
N5980_14835	COG0708	Exodeoxyribonuclease III
N5980_14855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N5980_14865	COG3706	GGDEF domain
N5980_14915	COG3150	esterase
N5980_14925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N5980_14930	COG2918	glutathione biosynthetic process
N5980_14945	COG2733	membrane
N5980_14985	COG0753	catalase activity
N5980_15005	COG3830	Belongs to the UPF0237 family
N5980_15005	COG0560	Phosphoserine phosphatase
N5980_15020	COG0385	Bile acid
N5980_15025	COG1335	isochorismatase
N5980_15035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N5980_15045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N5980_15050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N5980_15055	COG3300	MHYT domain
N5980_15055	COG5001	Diguanylate cyclase
N5980_15060	COG2983	Belongs to the UPF0260 family
N5980_15065	COG5487	UPF0391 membrane protein
N5980_15075	COG3023	N-Acetylmuramoyl-L-alanine amidase
N5980_15095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N5980_15105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N5980_15110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N5980_15115	COG0546	phosphoglycolate phosphatase activity
N5980_15120	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_15150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N5980_15150	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N5980_15155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N5980_15160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N5980_15165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N5980_15170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N5980_15175	COG1116	anion transmembrane transporter activity
N5980_15180	COG1309	transcriptional regulator
N5980_15190	COG0196	riboflavin kinase activity
N5980_15195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N5980_15205	COG1047	Peptidyl-prolyl cis-trans
N5980_15225	COG2133	pyrroloquinoline quinone binding
N5980_15265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N5980_15270	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N5980_15275	COG2951	lytic endotransglycosylase activity
N5980_15280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N5980_15295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N5980_15320	COG2814	Major facilitator Superfamily
N5980_15325	COG0861	Integral membrane protein TerC family
N5980_15330	COG0402	S-adenosylhomocysteine deaminase activity
N5980_15345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N5980_15350	COG1230	cation diffusion facilitator family transporter
N5980_15375	COG0706	membrane insertase activity
N5980_15380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N5980_15385	COG0594	ribonuclease P activity
N5980_15400	COG0579	oxidoreductase
N5980_15425	COG2130	NADP-dependent
N5980_15430	COG1309	transcriptional regulator
N5980_15440	COG1902	pentaerythritol trinitrate reductase activity
N5980_15450	COG1979	alcohol dehydrogenase
N5980_15460	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N5980_15475	COG3321	synthase
N5980_15475	COG0604	alcohol dehydrogenase
N5980_15480	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N5980_15485	COG0583	DNA-binding transcription factor activity
N5980_15490	COG4221	oxidoreductase activity
N5980_15540	COG4106	trans-aconitate 2-methyltransferase activity
N5980_15570	COG1215	transferase activity, transferring glycosyl groups
N5980_15585	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N5980_15605	COG2267	carboxylic ester hydrolase activity
N5980_15605	COG2226	methyltransferase
N5980_15630	COG4774	siderophore transport
N5980_15645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N5980_15670	COG1454	alcohol dehydrogenase
N5980_15690	COG4774	siderophore transport
N5980_15695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N5980_15745	COG1192	Involved in chromosome partitioning
N5980_15780	COG1346	cytolysis
N5980_15785	COG1380	Effector of murein hydrolase LrgA
N5980_15790	COG0583	DNA-binding transcription factor activity
N5980_15795	COG1309	transcriptional regulator
N5980_15800	COG0604	alcohol dehydrogenase
N5980_15845	COG1280	lysine exporter protein (LysE YggA)
N5980_15850	COG3706	GGDEF domain
N5980_15890	COG0431	NADPH-dependent FMN reductase
N5980_15895	COG0798	PFAM Bile acid sodium symporter
N5980_15905	COG0640	Transcriptional regulator
N5980_15915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N5980_15920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N5980_15980	COG2217	Heavy metal translocating P-type atpase
N5980_15990	COG2205	protein histidine kinase activity
N5980_16005	COG2132	Multicopper oxidase
N5980_16110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N5980_16120	COG1846	Transcriptional regulator
N5980_16125	COG1764	response to oxidative stress
N5980_16190	COG1373	ATPase (AAA superfamily
N5980_16215	COG1028	Short-chain dehydrogenase reductase Sdr
N5980_16265	COG4372	Transposase
N5980_16290	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N5980_16310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N5980_16315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N5980_16320	COG0730	response to heat
N5980_16325	COG0583	DNA-binding transcription factor activity
N5980_16335	COG2194	sulfuric ester hydrolase activity
N5980_16340	COG0745	RESPONSE REGULATOR receiver
N5980_16345	COG0642	Histidine kinase
N5980_16440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N5980_16460	COG2369	cell adhesion
N5980_16465	COG0582	viral genome integration into host DNA
N5980_16470	COG0789	Transcriptional regulator
N5980_16480	COG1230	cation diffusion facilitator family transporter
N5980_16510	COG0789	Transcriptional regulator
N5980_16560	COG1309	transcriptional regulator
N5980_16585	COG0633	Ferredoxin
N5980_16590	COG2207	Transcriptional regulator
N5980_16695	COG3293	Transposase
N5980_16700	COG2076	Multidrug Resistance protein
N5980_16735	COG2826	transposase and inactivated derivatives, IS30 family
N5980_16765	COG1324	tolerance protein
N5980_16790	COG2826	transposase and inactivated derivatives, IS30 family
N5980_16800	COG2826	transposase and inactivated derivatives, IS30 family
N5980_16810	COG2801	Transposase and inactivated derivatives
N5980_16830	COG3657	addiction module killer protein
N5980_16835	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N5980_16840	COG3328	transposase activity
N5980_16845	COG2801	Transposase and inactivated derivatives
N5980_16865	COG0488	(ABC) transporter
N5980_16870	COG3173	Aminoglycoside phosphotransferase
N5980_16875	COG2801	Transposase and inactivated derivatives
N5980_16885	COG2801	Transposase and inactivated derivatives
N5980_16955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N5980_16970	COG0789	Transcriptional regulator