locus-tag	class	description
IAQ69_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAQ69_00010	COG0592	DNA-directed DNA polymerase activity
IAQ69_00020	COG0187	DNA topoisomerase II activity
IAQ69_00030	COG1063	alcohol dehydrogenase
IAQ69_00040	COG0488	(ABC) transporter
IAQ69_00065	COG3385	transposase activity
IAQ69_00100	COG0657	acetylesterase activity
IAQ69_00110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAQ69_00140	COG4251	negative regulation of phosphorylation
IAQ69_00140	COG5001	Diguanylate cyclase
IAQ69_00140	COG3706	GGDEF domain
IAQ69_00140	COG2203	Gaf domain
IAQ69_00145	COG2133	pyrroloquinoline quinone binding
IAQ69_00160	COG1047	Peptidyl-prolyl cis-trans
IAQ69_00170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAQ69_00175	COG0196	riboflavin kinase activity
IAQ69_00185	COG1309	transcriptional regulator
IAQ69_00190	COG1116	anion transmembrane transporter activity
IAQ69_00195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_00200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ69_00205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_00210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_00215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IAQ69_00215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAQ69_00240	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_00245	COG0546	phosphoglycolate phosphatase activity
IAQ69_00250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAQ69_00255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAQ69_00260	COG1309	transcriptional regulator
IAQ69_00265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IAQ69_00275	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAQ69_00285	COG5487	UPF0391 membrane protein
IAQ69_00290	COG2983	Belongs to the UPF0260 family
IAQ69_00295	COG5001	Diguanylate cyclase
IAQ69_00295	COG3300	MHYT domain
IAQ69_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAQ69_00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAQ69_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAQ69_00340	COG1335	isochorismatase
IAQ69_00345	COG0385	Bile acid
IAQ69_00355	COG3830	Belongs to the UPF0237 family
IAQ69_00355	COG0560	Phosphoserine phosphatase
IAQ69_00375	COG0753	catalase activity
IAQ69_00415	COG2733	membrane
IAQ69_00430	COG2918	glutathione biosynthetic process
IAQ69_00435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAQ69_00445	COG3150	esterase
IAQ69_00495	COG3706	GGDEF domain
IAQ69_00500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAQ69_00515	COG1393	Belongs to the ArsC family
IAQ69_00520	COG0708	Exodeoxyribonuclease III
IAQ69_00540	COG0189	ligase activity
IAQ69_00555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAQ69_00565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAQ69_00575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAQ69_00605	COG2119	membrane
IAQ69_00610	COG0426	domain, Protein
IAQ69_00610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ69_00640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAQ69_00670	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_00675	COG1519	Transferase
IAQ69_00680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAQ69_00685	COG0668	transmembrane transport
IAQ69_00695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAQ69_00710	COG0307	riboflavin synthase, alpha
IAQ69_00720	COG0431	NADPH-dependent FMN reductase
IAQ69_00735	COG2205	protein histidine kinase activity
IAQ69_00735	COG2198	Histidine kinase
IAQ69_00735	COG0784	Response regulator, receiver
IAQ69_00740	COG3162	membrane
IAQ69_00745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAQ69_00755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAQ69_00770	COG3706	GGDEF domain
IAQ69_00775	COG0537	adenosine 5'-monophosphoramidase activity
IAQ69_00785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAQ69_00785	COG0352	thiamine-phosphate diphosphorylase activity
IAQ69_00785	COG0351	phosphomethylpyrimidine kinase
IAQ69_00800	COG2814	Major facilitator Superfamily
IAQ69_00805	COG0629	single-stranded DNA binding
IAQ69_00860	COG3158	transport of potassium into the cell
IAQ69_00895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IAQ69_00925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAQ69_00980	COG0183	Belongs to the thiolase family
IAQ69_00985	COG1024	Enoyl-CoA hydratase
IAQ69_00985	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_01015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAQ69_01030	COG3275	phosphorelay sensor kinase activity
IAQ69_01040	COG0181	hydroxymethylbilane synthase activity
IAQ69_01060	COG0824	Thioesterase
IAQ69_01085	COG1716	ATPase activity
IAQ69_01090	COG0546	phosphoglycolate phosphatase activity
IAQ69_01150	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAQ69_01165	COG0085	RNA polymerase activity
IAQ69_01170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAQ69_01190	COG2056	Na+-H+ antiporter family
IAQ69_01195	COG3047	cAMP biosynthetic process
IAQ69_01205	COG0326	Molecular chaperone. Has ATPase activity
IAQ69_01240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAQ69_01245	COG0427	acetyl-CoA hydrolase
IAQ69_01285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAQ69_01295	COG2226	methyltransferase
IAQ69_01315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IAQ69_01320	COG1074	ATP-dependent DNA helicase activity
IAQ69_01325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAQ69_01330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAQ69_01340	COG2841	Protein conserved in bacteria
IAQ69_01345	COG0789	Transcriptional regulator
IAQ69_01365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAQ69_01375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAQ69_01405	COG4535	Mg2 and Co2 transporter CorC
IAQ69_01430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAQ69_01430	COG0644	oxidoreductase
IAQ69_01440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAQ69_01455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ69_01465	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IAQ69_01475	COG0644	oxidoreductase
IAQ69_01485	COG2226	methyltransferase
IAQ69_01500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAQ69_01525	COG0751	glycine-tRNA ligase activity
IAQ69_01530	COG0752	glycyl-tRNA synthetase alpha subunit
IAQ69_01540	COG0517	IMP dehydrogenase activity
IAQ69_01540	COG0617	tRNA 3'-terminal CCA addition
IAQ69_01540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IAQ69_01545	COG0471	metal ion transport
IAQ69_01555	COG1983	PspC domain protein
IAQ69_01580	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_01585	COG1530	ribonuclease E activity
IAQ69_01595	COG0546	phosphoglycolate phosphatase activity
IAQ69_01600	COG3971	2-oxopent-4-enoate hydratase activity
IAQ69_01605	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IAQ69_01625	COG0583	DNA-binding transcription factor activity
IAQ69_01630	COG4638	Rieske (2fe-2S)
IAQ69_01645	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_01650	COG3384	dioxygenase
IAQ69_01655	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ69_01665	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ69_01685	COG0753	catalase activity
IAQ69_01735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAQ69_01750	COG0473	3-isopropylmalate dehydrogenase activity
IAQ69_01810	COG1560	Kdo2-lipid A biosynthetic process
IAQ69_01815	COG0488	(ABC) transporter
IAQ69_01820	COG2900	Belongs to the SlyX family
IAQ69_01860	COG1929	Belongs to the glycerate kinase type-1 family
IAQ69_01865	COG0210	DNA helicase
IAQ69_01870	COG0724	RNA recognition motif
IAQ69_01885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAQ69_01885	COG4651	solute:proton antiporter activity
IAQ69_01910	COG0788	formyltetrahydrofolate deformylase activity
IAQ69_01945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IAQ69_01955	COG3040	lipid binding
IAQ69_02000	COG2813	Specifically methylates the guanine in position
IAQ69_02000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ69_02005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ69_02010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAQ69_02015	COG4774	siderophore transport
IAQ69_02025	COG3128	pkhd-type hydroxylase
IAQ69_02030	COG4774	siderophore transport
IAQ69_02035	COG4774	siderophore transport
IAQ69_02045	COG0740	serine-type endopeptidase activity
IAQ69_02065	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IAQ69_02065	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAQ69_02075	COG0857	belongs to the CobB CobQ family
IAQ69_02075	COG0280	phosphate acetyltransferase
IAQ69_02080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAQ69_02105	COG0793	Belongs to the peptidase S41A family
IAQ69_02115	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAQ69_02130	COG0084	hydrolase, TatD family'
IAQ69_02160	COG1162	GTPase activity
IAQ69_02165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IAQ69_02175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAQ69_02185	COG1538	Outer membrane efflux protein
IAQ69_02190	COG0577	efflux transmembrane transporter activity
IAQ69_02190	COG1136	(ABC) transporter
IAQ69_02195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_02200	COG2703	oxygen carrier activity
IAQ69_02225	COG0028	Belongs to the TPP enzyme family
IAQ69_02245	COG2975	iron-sulfur cluster assembly
IAQ69_02265	COG1426	Protein conserved in bacteria
IAQ69_02315	COG4221	oxidoreductase activity
IAQ69_02320	COG3956	TIGRFAM MazG family protein
IAQ69_02325	COG1596	polysaccharide export
IAQ69_02325	COG1555	photosystem II stabilization
IAQ69_02330	COG0617	tRNA 3'-terminal CCA addition
IAQ69_02335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAQ69_02350	COG1660	Displays ATPase and GTPase activities
IAQ69_02365	COG2205	protein histidine kinase activity
IAQ69_02370	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IAQ69_02430	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAQ69_02475	COG1960	acyl-CoA dehydrogenase activity
IAQ69_02480	COG1960	acyl-CoA dehydrogenase activity
IAQ69_02490	COG2205	protein histidine kinase activity
IAQ69_02495	COG0745	RESPONSE REGULATOR receiver
IAQ69_02505	COG1113	amino acid transport
IAQ69_02515	COG2315	Protein conserved in bacteria
IAQ69_02520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IAQ69_02535	COG2096	Adenosyltransferase
IAQ69_02540	COG4206	TonB-dependent receptor
IAQ69_02585	COG0285	dihydrofolate synthase activity
IAQ69_02600	COG0450	alkyl hydroperoxide reductase
IAQ69_02615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAQ69_02620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IAQ69_02700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAQ69_02705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAQ69_02750	COG3385	transposase activity
IAQ69_02760	COG0494	nUDIX hydrolase
IAQ69_02770	COG1214	PFAM Peptidase M22, glycoprotease
IAQ69_02775	COG1968	undecaprenyl-diphosphatase activity
IAQ69_02790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IAQ69_02795	COG4269	membrane
IAQ69_02805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAQ69_02815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAQ69_02830	COG2814	Major facilitator Superfamily
IAQ69_02835	COG2030	dehydratase
IAQ69_02835	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_02840	COG3293	Transposase
IAQ69_02845	COG3396	Phenylacetate-CoA oxygenase
IAQ69_02850	COG3460	Phenylacetate-CoA oxygenase
IAQ69_02855	COG3396	Phenylacetate-CoA oxygenase
IAQ69_02860	COG2151	metal-sulfur cluster biosynthetic enzyme
IAQ69_02865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAQ69_02870	COG1024	Enoyl-CoA hydratase
IAQ69_02875	COG0183	Belongs to the thiolase family
IAQ69_02880	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IAQ69_02885	COG3327	negative regulation of DNA-templated transcription, initiation
IAQ69_02905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAQ69_02915	COG3545	Serine hydrolase
IAQ69_02930	COG0730	response to heat
IAQ69_02940	COG1196	nuclear chromosome segregation
IAQ69_02950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAQ69_02955	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IAQ69_02960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAQ69_02965	COG2193	ferroxidase activity
IAQ69_02985	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IAQ69_02995	COG4166	transmembrane transport
IAQ69_03005	COG0339	signal peptide processing
IAQ69_03035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAQ69_03040	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAQ69_03055	COG0009	L-threonylcarbamoyladenylate synthase
IAQ69_03060	COG3101	peptidyl-lysine hydroxylation
IAQ69_03065	COG1399	metal-binding, possibly nucleic acid-binding protein
IAQ69_03070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IAQ69_03080	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_03085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAQ69_03090	COG1652	LysM domain
IAQ69_03110	COG0251	oxidation-reduction process
IAQ69_03115	COG1113	amino acid transport
IAQ69_03120	COG1981	membrane
IAQ69_03135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAQ69_03145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAQ69_03160	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_03165	COG0456	acetyltransferase
IAQ69_03175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IAQ69_03180	COG0492	ferredoxin-NADP+ reductase activity
IAQ69_03185	COG0531	amino acid
IAQ69_03185	COG1674	ftsk spoiiie
IAQ69_03205	COG0850	regulation of cytokinetic process
IAQ69_03215	COG0204	Acyl-transferase
IAQ69_03220	COG2885	chlorophyll binding
IAQ69_03230	COG0756	dUTP diphosphatase activity
IAQ69_03245	COG0121	glutamine amidotransferase
IAQ69_03260	COG2914	Belongs to the UPF0125 (RnfH) family
IAQ69_03265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAQ69_03270	COG0735	belongs to the Fur family
IAQ69_03300	COG0420	3'-5' exonuclease activity
IAQ69_03310	COG1090	epimerase
IAQ69_03315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAQ69_03325	COG2050	protein possibly involved in aromatic compounds catabolism
IAQ69_03330	COG1566	PFAM secretion protein HlyD family protein
IAQ69_03335	COG2814	Major facilitator Superfamily
IAQ69_03340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAQ69_03450	COG0443	Heat shock 70 kDa protein
IAQ69_03455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ69_03470	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_03475	COG0129	dihydroxy-acid dehydratase activity
IAQ69_03485	COG0583	DNA-binding transcription factor activity
IAQ69_03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAQ69_03505	COG2084	Dehydrogenase
IAQ69_03510	COG2814	Major facilitator Superfamily
IAQ69_03515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAQ69_03520	COG2186	Transcriptional regulator
IAQ69_03540	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_03565	COG0604	alcohol dehydrogenase
IAQ69_03570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_03585	COG0625	glutathione transferase activity
IAQ69_03610	COG1448	Aminotransferase
IAQ69_03615	COG1113	amino acid transport
IAQ69_03630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAQ69_03635	COG0596	Alpha beta hydrolase
IAQ69_03650	COG4106	trans-aconitate 2-methyltransferase activity
IAQ69_03675	COG0583	DNA-binding transcription factor activity
IAQ69_03690	COG2223	nitrite transmembrane transporter activity
IAQ69_03695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_03700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_03705	COG0243	molybdopterin cofactor binding
IAQ69_03715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAQ69_03725	COG0314	molybdopterin synthase activity
IAQ69_03730	COG0315	cyclic pyranopterin monophosphate synthase activity
IAQ69_03730	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAQ69_03735	COG0303	'Molybdopterin
IAQ69_03740	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAQ69_03745	COG4149	molybdate abc transporter
IAQ69_03750	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IAQ69_03775	COG0783	Belongs to the Dps family
IAQ69_03800	COG0500	methyltransferase
IAQ69_03810	COG2223	nitrite transmembrane transporter activity
IAQ69_03815	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IAQ69_03830	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IAQ69_03845	COG3590	peptidase
IAQ69_03850	COG3590	peptidase
IAQ69_03860	COG0697	spore germination
IAQ69_03875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAQ69_03885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAQ69_03890	COG1077	Cell shape determining protein MreB Mrl
IAQ69_03895	COG1792	Involved in formation and maintenance of cell shape
IAQ69_03900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IAQ69_03905	COG0424	maF-like protein
IAQ69_03920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAQ69_03930	COG0560	Phosphoserine phosphatase
IAQ69_03950	COG1113	amino acid transport
IAQ69_03955	COG2828	Protein conserved in bacteria
IAQ69_03960	COG0142	geranyltranstransferase activity
IAQ69_03965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAQ69_03980	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAQ69_04005	COG2323	membrane
IAQ69_04020	COG2852	Protein conserved in bacteria
IAQ69_04035	COG3385	transposase activity
IAQ69_04040	COG0525	valine-tRNA ligase activity
IAQ69_04050	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_04055	COG2066	Belongs to the glutaminase family
IAQ69_04060	COG2376	Dihydroxyacetone kinase
IAQ69_04065	COG2852	Protein conserved in bacteria
IAQ69_04080	COG0306	phosphate transporter
IAQ69_04090	COG4607	ABC-type enterochelin transport system periplasmic component
IAQ69_04105	COG4771	TonB-dependent receptor
IAQ69_04130	COG4181	ATPase activity
IAQ69_04135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IAQ69_04145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ69_04160	COG0583	DNA-binding transcription factor activity
IAQ69_04170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_04175	COG1773	rubredoxin
IAQ69_04180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAQ69_04210	COG2354	Protein conserved in bacteria
IAQ69_04215	COG2321	neutral zinc metallopeptidase
IAQ69_04235	COG0589	response to stress
IAQ69_04250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IAQ69_04250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ69_04270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IAQ69_04275	COG1053	succinate dehydrogenase
IAQ69_04280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAQ69_04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ69_04305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAQ69_04310	COG2268	Band 7 protein
IAQ69_04365	COG3118	belongs to the thioredoxin family
IAQ69_04375	COG0604	alcohol dehydrogenase
IAQ69_04375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAQ69_04375	COG3321	synthase
IAQ69_04375	COG4221	oxidoreductase activity
IAQ69_04400	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAQ69_04415	COG0477	Major facilitator Superfamily
IAQ69_04425	COG1597	lipid kinase activity
IAQ69_04495	COG0742	ribosomal rna small subunit methyltransferase
IAQ69_04500	COG0768	penicillin binding
IAQ69_04525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAQ69_04530	COG2878	Part of a membrane complex involved in electron transport
IAQ69_04535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAQ69_04545	COG3384	dioxygenase
IAQ69_04550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAQ69_04555	COG2234	aminopeptidase activity
IAQ69_04565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAQ69_04590	COG0006	proline dipeptidase activity
IAQ69_04595	COG2155	Conserved Protein
IAQ69_04600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAQ69_04615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAQ69_04620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAQ69_04635	COG3107	peptidoglycan biosynthetic process
IAQ69_04650	COG0657	acetylesterase activity
IAQ69_04670	COG0741	lytic transglycosylase activity
IAQ69_04670	COG1388	LysM domain
IAQ69_04675	COG4166	transmembrane transport
IAQ69_04680	COG4174	ABC transporter (Permease)
IAQ69_04685	COG4239	(ABC) transporter, permease
IAQ69_04725	COG0833	amino acid
IAQ69_04735	COG0833	amino acid
IAQ69_04750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAQ69_04755	COG0418	dihydroorotase activity
IAQ69_04760	COG3706	GGDEF domain
IAQ69_04775	COG1620	l-lactate permease
IAQ69_04780	COG2186	Transcriptional regulator
IAQ69_04790	COG0277	FAD linked oxidase domain protein
IAQ69_04800	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_04800	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ69_04810	COG0281	malic enzyme
IAQ69_04845	COG1741	Belongs to the pirin family
IAQ69_04860	COG3739	integral membrane protein
IAQ69_04875	COG3706	GGDEF domain
IAQ69_04890	COG0302	gtp cyclohydrolase
IAQ69_04910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAQ69_04915	COG0512	Glutamine amidotransferase of anthranilate synthase
IAQ69_04920	COG0174	glutamine synthetase
IAQ69_04930	COG3161	chorismate lyase activity
IAQ69_04935	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IAQ69_04975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAQ69_04980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAQ69_04985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ69_04995	COG0596	Alpha beta hydrolase
IAQ69_05000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ69_05005	COG1335	isochorismatase
IAQ69_05010	COG0251	oxidation-reduction process
IAQ69_05015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ69_05020	COG2233	PERMEase
IAQ69_05025	COG2084	Dehydrogenase
IAQ69_05035	COG1960	acyl-CoA dehydrogenase activity
IAQ69_05045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAQ69_05050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ69_05060	COG2175	clavaminate synthase activity
IAQ69_05085	COG0556	nucleotide-excision repair
IAQ69_05090	COG3040	lipid binding
IAQ69_05105	COG1733	regulation of RNA biosynthetic process
IAQ69_05145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAQ69_05150	COG0076	glutamate decarboxylase activity
IAQ69_05160	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_05165	COG1522	sequence-specific DNA binding
IAQ69_05170	COG3961	Belongs to the TPP enzyme family
IAQ69_05175	COG1113	amino acid transport
IAQ69_05180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAQ69_05185	COG0573	inorganic phosphate transmembrane transporter activity
IAQ69_05195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAQ69_05205	COG0616	signal peptide processing
IAQ69_05245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAQ69_05245	COG2755	lipolytic protein G-D-S-L family
IAQ69_05250	COG0488	(ABC) transporter
IAQ69_05260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IAQ69_05265	COG1686	Belongs to the peptidase S11 family
IAQ69_05290	COG0583	DNA-binding transcription factor activity
IAQ69_05295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAQ69_05300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IAQ69_05305	COG1067	ATP-dependent peptidase activity
IAQ69_05345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAQ69_05350	COG1966	Carbon starvation protein
IAQ69_05355	COG2879	small protein
IAQ69_05375	COG0714	Associated with various cellular activities
IAQ69_05395	COG0582	viral genome integration into host DNA
IAQ69_05400	COG0582	viral genome integration into host DNA
IAQ69_05425	COG3620	sequence-specific DNA binding
IAQ69_05440	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IAQ69_05445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IAQ69_05500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ69_05510	COG1401	restriction endodeoxyribonuclease activity
IAQ69_05580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAQ69_05585	COG1765	OsmC-like protein
IAQ69_05595	COG0667	Aldo Keto reductase
IAQ69_05620	COG0540	Belongs to the ATCase OTCase family
IAQ69_05635	COG2031	fatty acid transporter
IAQ69_05640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_05655	COG4770	biotin carboxylase activity
IAQ69_05660	COG1024	Enoyl-CoA hydratase
IAQ69_05665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAQ69_05670	COG1960	acyl-CoA dehydrogenase activity
IAQ69_05675	COG1309	transcriptional regulator
IAQ69_05680	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_05700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAQ69_05705	COG0659	secondary active sulfate transmembrane transporter activity
IAQ69_05720	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAQ69_05745	COG2363	Small membrane protein
IAQ69_05765	COG0513	Belongs to the DEAD box helicase family
IAQ69_05775	COG0778	Nitroreductase
IAQ69_05855	COG2199	diguanylate cyclase activity
IAQ69_05855	COG2203	Gaf domain
IAQ69_05875	COG0515	serine threonine protein kinase
IAQ69_05875	COG2815	serine threonine protein kinase
IAQ69_05925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ69_05940	COG0612	Peptidase, M16
IAQ69_05960	COG3025	triphosphatase activity
IAQ69_05975	COG0352	thiamine-phosphate diphosphorylase activity
IAQ69_06025	COG2267	carboxylic ester hydrolase activity
IAQ69_06085	COG2391	methyltransferase activity
IAQ69_06105	COG3293	Transposase
IAQ69_06110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAQ69_06125	COG2353	YceI-like domain
IAQ69_06130	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ69_06130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAQ69_06135	COG0625	glutathione transferase activity
IAQ69_06160	COG0644	oxidoreductase
IAQ69_06160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IAQ69_06165	COG2814	Major facilitator Superfamily
IAQ69_06170	COG1960	acyl-CoA dehydrogenase activity
IAQ69_06175	COG1024	Enoyl-CoA hydratase
IAQ69_06180	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_06185	COG0183	Belongs to the thiolase family
IAQ69_06190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAQ69_06215	COG0517	IMP dehydrogenase activity
IAQ69_06215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IAQ69_06220	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IAQ69_06230	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IAQ69_06235	COG1137	ATPase activity
IAQ69_06270	COG4122	O-methyltransferase activity
IAQ69_06280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IAQ69_06315	COG2011	ABC-type metal ion transport system permease component
IAQ69_06320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ69_06325	COG1464	Belongs to the NlpA lipoprotein family
IAQ69_06345	COG0138	bifunctional purine biosynthesis protein purh
IAQ69_06350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IAQ69_06380	COG0445	tRNA wobble uridine modification
IAQ69_06400	COG3852	Histidine kinase
IAQ69_06420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAQ69_06425	COG0575	Belongs to the CDS family
IAQ69_06440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAQ69_06455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAQ69_06460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAQ69_06475	COG2137	regulation of response to DNA damage stimulus
IAQ69_06485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAQ69_06490	COG1011	Hydrolase
IAQ69_06505	COG0268	Binds directly to 16S ribosomal RNA
IAQ69_06510	COG0702	epimerase
IAQ69_06515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAQ69_06525	COG2197	response regulator
IAQ69_06530	COG4585	Histidine kinase
IAQ69_06535	COG2850	peptidyl-arginine hydroxylation
IAQ69_06540	COG0424	maF-like protein
IAQ69_06565	COG0697	spore germination
IAQ69_06600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ69_06605	COG3781	membrane
IAQ69_06625	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAQ69_06625	COG0506	proline dehydrogenase activity
IAQ69_06625	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAQ69_06640	COG1027	Aspartate ammonia-lyase
IAQ69_06650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAQ69_06680	COG0316	Belongs to the HesB IscA family
IAQ69_06685	COG0822	iron-sulfur transferase activity
IAQ69_06695	COG1959	2 iron, 2 sulfur cluster binding
IAQ69_06715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAQ69_06735	COG1585	Membrane protein implicated in regulation of membrane protease activity
IAQ69_06745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAQ69_06765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAQ69_06770	COG0569	domain protein
IAQ69_06775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAQ69_06780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAQ69_06800	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IAQ69_06805	COG0542	response to heat
IAQ69_06840	COG0372	Belongs to the citrate synthase family
IAQ69_06850	COG1546	Belongs to the CinA family
IAQ69_06850	COG1058	Belongs to the CinA family
IAQ69_06860	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_06880	COG4680	protein conserved in bacteria
IAQ69_06885	COG5499	transcription regulator containing HTH domain
IAQ69_06895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ69_06935	COG2814	Major facilitator Superfamily
IAQ69_06945	COG3706	GGDEF domain
IAQ69_06955	COG0439	Biotin carboxylase
IAQ69_06970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAQ69_07005	COG0582	viral genome integration into host DNA
IAQ69_07055	COG2199	diguanylate cyclase activity
IAQ69_07055	COG2203	Gaf domain
IAQ69_07170	COG5410	chromosome segregation
IAQ69_07230	COG4372	Transposase
IAQ69_07355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAQ69_07395	COG0596	Alpha beta hydrolase
IAQ69_07515	COG0830	nickel cation binding
IAQ69_07530	COG0829	nickel cation binding
IAQ69_07545	COG0804	urea catabolic process
IAQ69_07570	COG4772	TonB-dependent receptor
IAQ69_07605	COG1289	transmembrane transporter activity
IAQ69_07615	COG0583	DNA-binding transcription factor activity
IAQ69_07635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAQ69_07640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAQ69_07665	COG2116	formate transmembrane transporter activity
IAQ69_07670	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IAQ69_07675	COG4773	Receptor
IAQ69_07700	COG2132	Multicopper oxidase
IAQ69_07725	COG0640	Transcriptional regulator
IAQ69_07730	COG1136	(ABC) transporter
IAQ69_07745	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_07760	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_07770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAQ69_07775	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_07785	COG2814	Major facilitator Superfamily
IAQ69_07790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAQ69_07795	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_07800	COG2814	Major facilitator Superfamily
IAQ69_07815	COG1960	acyl-CoA dehydrogenase activity
IAQ69_07825	COG1024	Enoyl-CoA hydratase
IAQ69_07830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAQ69_07835	COG0235	Class ii aldolase
IAQ69_07845	COG0183	Belongs to the thiolase family
IAQ69_07850	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_07860	COG2814	Major facilitator Superfamily
IAQ69_07870	COG2814	Major facilitator Superfamily
IAQ69_07880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_07885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAQ69_07890	COG2814	Major facilitator Superfamily
IAQ69_07895	COG1960	acyl-CoA dehydrogenase activity
IAQ69_07900	COG1960	acyl-CoA dehydrogenase activity
IAQ69_07910	COG1944	ATP diphosphatase activity
IAQ69_07930	COG1309	transcriptional regulator
IAQ69_07935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAQ69_07960	COG1116	anion transmembrane transporter activity
IAQ69_07960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_07965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ69_07970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_08015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAQ69_08025	COG0864	Transcriptional regulator
IAQ69_08030	COG2885	chlorophyll binding
IAQ69_08030	COG3047	cAMP biosynthetic process
IAQ69_08045	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IAQ69_08050	COG3385	transposase activity
IAQ69_08055	COG0439	Biotin carboxylase
IAQ69_08070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAQ69_08090	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_08100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAQ69_08110	COG2814	Major facilitator Superfamily
IAQ69_08115	COG0583	DNA-binding transcription factor activity
IAQ69_08120	COG4948	Mandelate Racemase Muconate Lactonizing
IAQ69_08125	COG4829	muconolactone delta-isomerase
IAQ69_08135	COG4638	Rieske (2fe-2S)
IAQ69_08140	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IAQ69_08145	COG0543	2 iron, 2 sulfur cluster binding
IAQ69_08145	COG0633	Ferredoxin
IAQ69_08150	COG1028	Short-chain dehydrogenase reductase Sdr
IAQ69_08155	COG3135	benzoate transporter
IAQ69_08160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAQ69_08165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAQ69_08170	COG0183	Belongs to the thiolase family
IAQ69_08175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAQ69_08195	COG0427	acetyl-CoA hydrolase
IAQ69_08200	COG0183	Belongs to the thiolase family
IAQ69_08205	COG1960	acyl-CoA dehydrogenase activity
IAQ69_08220	COG0789	Transcriptional regulator
IAQ69_08230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAQ69_08235	COG0640	Transcriptional regulator
IAQ69_08255	COG3122	Protein conserved in bacteria
IAQ69_08270	COG0668	transmembrane transport
IAQ69_08275	COG1132	(ABC) transporter
IAQ69_08285	COG0509	glycine decarboxylation via glycine cleavage system
IAQ69_08290	COG2814	Major facilitator Superfamily
IAQ69_08305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAQ69_08315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IAQ69_08320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAQ69_08375	COG1525	nuclease
IAQ69_08385	COG1294	oxidase, subunit
IAQ69_08390	COG1271	oxidase subunit
IAQ69_08405	COG1476	TRANSCRIPTIONal
IAQ69_08420	COG1960	acyl-CoA dehydrogenase activity
IAQ69_08425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAQ69_08430	COG2207	Transcriptional regulator
IAQ69_08435	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAQ69_08440	COG0730	response to heat
IAQ69_08445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAQ69_08515	COG1960	acyl-CoA dehydrogenase activity
IAQ69_08570	COG0552	protein localization to endoplasmic reticulum
IAQ69_08575	COG0612	Peptidase, M16
IAQ69_08605	COG0517	IMP dehydrogenase activity
IAQ69_08605	COG0516	GMP reductase activity
IAQ69_08610	COG0133	tryptophan synthase activity
IAQ69_08620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ69_08640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAQ69_08700	COG1294	oxidase, subunit
IAQ69_08705	COG4890	Cyd operon protein YbgT
IAQ69_08720	COG0772	Belongs to the SEDS family
IAQ69_08735	COG0148	phosphopyruvate hydratase activity
IAQ69_08755	COG3385	transposase activity
IAQ69_08770	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_08770	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAQ69_08785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAQ69_08790	COG0583	DNA-binding transcription factor activity
IAQ69_08820	COG0786	glutamate:sodium symporter activity
IAQ69_08860	COG1570	exodeoxyribonuclease VII activity
IAQ69_08870	COG3385	transposase activity
IAQ69_08880	COG0729	surface antigen
IAQ69_08885	COG0477	Major facilitator Superfamily
IAQ69_08900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAQ69_08910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAQ69_08925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAQ69_08930	COG1960	acyl-CoA dehydrogenase activity
IAQ69_08950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_08955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_08965	COG2890	protein-(glutamine-N5) methyltransferase activity
IAQ69_08970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAQ69_08990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAQ69_09015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAQ69_09020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAQ69_09025	COG1845	cytochrome c oxidase, subunit III
IAQ69_09030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAQ69_09040	COG0360	Binds together with S18 to 16S ribosomal RNA
IAQ69_09055	COG0305	Participates in initiation and elongation during chromosome replication
IAQ69_09065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAQ69_09080	COG1305	Transglutaminase-like
IAQ69_09090	COG2308	Evidence 4 Homologs of previously reported genes of
IAQ69_09100	COG0069	glutamate synthase activity
IAQ69_09125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAQ69_09130	COG1454	alcohol dehydrogenase
IAQ69_09135	COG0824	Thioesterase
IAQ69_09165	COG0183	Belongs to the thiolase family
IAQ69_09180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAQ69_09190	COG3135	benzoate transporter
IAQ69_09210	COG0589	response to stress
IAQ69_09215	COG0589	response to stress
IAQ69_09230	COG0308	aminopeptidase N
IAQ69_09250	COG1253	flavin adenine dinucleotide binding
IAQ69_09270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IAQ69_09275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IAQ69_09290	COG2431	L-lysine efflux transmembrane transporter activity
IAQ69_09310	COG0776	regulation of translation
IAQ69_09340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAQ69_09370	COG1309	transcriptional regulator
IAQ69_09375	COG0084	hydrolase, TatD family'
IAQ69_09395	COG1663	tetraacyldisaccharide 4'-kinase activity
IAQ69_09400	COG1132	(ABC) transporter
IAQ69_09410	COG0811	peptide transport
IAQ69_09415	COG1475	DNA binding
IAQ69_09420	COG1192	Involved in chromosome partitioning
IAQ69_09430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAQ69_09435	COG3178	'Phosphotransferase
IAQ69_09445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAQ69_09450	COG1923	regulation of RNA biosynthetic process
IAQ69_09460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAQ69_09465	COG0802	atpase or kinase
IAQ69_09490	COG2707	UPF0756 membrane protein
IAQ69_09495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAQ69_09515	COG1643	Atp-dependent helicase
IAQ69_09540	COG3634	alkyl hydroperoxide reductase activity
IAQ69_09575	COG1254	Belongs to the acylphosphatase family
IAQ69_09580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAQ69_09580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAQ69_09660	COG1464	Belongs to the NlpA lipoprotein family
IAQ69_09665	COG1464	Belongs to the NlpA lipoprotein family
IAQ69_09670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAQ69_09675	COG2011	ABC-type metal ion transport system permease component
IAQ69_09680	COG0012	GTP binding
IAQ69_09685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAQ69_09695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IAQ69_09710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IAQ69_09720	COG0386	Belongs to the glutathione peroxidase family
IAQ69_09725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAQ69_09730	COG0436	Aminotransferase
IAQ69_09745	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_09770	COG1187	pseudouridine synthase activity
IAQ69_09790	COG2351	hydroxyisourate hydrolase activity
IAQ69_09795	COG2050	protein possibly involved in aromatic compounds catabolism
IAQ69_09805	COG1686	Belongs to the peptidase S11 family
IAQ69_09810	COG1252	NADH dehydrogenase
IAQ69_09830	COG0501	Belongs to the peptidase M48B family
IAQ69_09835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAQ69_09860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAQ69_09870	COG0527	aspartate kinase activity
IAQ69_09885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAQ69_09900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IAQ69_09905	COG2252	PERMEase
IAQ69_09935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAQ69_09940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAQ69_09950	COG0693	protein deglycase activity
IAQ69_09955	COG1960	acyl-CoA dehydrogenase activity
IAQ69_09965	COG1301	dicarboxylic acid transport
IAQ69_09975	COG3139	Protein of unknown function (DUF1315)
IAQ69_09980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAQ69_09985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAQ69_09995	COG0494	nUDIX hydrolase
IAQ69_10005	COG0642	Histidine kinase
IAQ69_10020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAQ69_10035	COG1720	tRNA m6t6A37 methyltransferase activity
IAQ69_10045	COG3293	Transposase
IAQ69_10050	COG4993	Dehydrogenase
IAQ69_10075	COG0826	peptidase U32
IAQ69_10080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAQ69_10085	COG3634	alkyl hydroperoxide reductase activity
IAQ69_10110	COG2862	Uncharacterized protein family, UPF0114
IAQ69_10165	COG1131	(ABC) transporter
IAQ69_10170	COG0842	Transport permease protein
IAQ69_10185	COG2951	lytic endotransglycosylase activity
IAQ69_10210	COG0052	Belongs to the universal ribosomal protein uS2 family
IAQ69_10220	COG0436	Aminotransferase
IAQ69_10225	COG0534	Mate efflux family protein
IAQ69_10255	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IAQ69_10260	COG1381	Involved in DNA repair and RecF pathway recombination
IAQ69_10270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAQ69_10275	COG0571	ribonuclease III activity
IAQ69_10300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAQ69_10320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAQ69_10330	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ69_10335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ69_10345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IAQ69_10350	COG4208	sulfate ABC transporter
IAQ69_10355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IAQ69_10360	COG0583	DNA-binding transcription factor activity
IAQ69_10380	COG0602	queuosine metabolic process
IAQ69_10385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAQ69_10395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAQ69_10400	COG1279	arginine transmembrane transporter activity
IAQ69_10405	COG0583	DNA-binding transcription factor activity
IAQ69_10410	COG2353	YceI-like domain
IAQ69_10415	COG1051	belongs to the nudix hydrolase family
IAQ69_10415	COG1056	cytidyltransferase-related domain
IAQ69_10420	COG1024	Enoyl-CoA hydratase
IAQ69_10430	COG0778	Nitroreductase
IAQ69_10440	COG0583	DNA-binding transcription factor activity
IAQ69_10445	COG0047	phosphoribosylformylglycinamidine synthase activity
IAQ69_10445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAQ69_10465	COG2255	four-way junction helicase activity
IAQ69_10470	COG1473	amidohydrolase
IAQ69_10475	COG0824	Thioesterase
IAQ69_10495	COG0823	Involved in the tonB-independent uptake of proteins
IAQ69_10515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAQ69_10545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAQ69_10550	COG0628	permease
IAQ69_10555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IAQ69_10560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAQ69_10565	COG2267	carboxylic ester hydrolase activity
IAQ69_10580	COG0658	competence protein
IAQ69_10580	COG2333	competence protein COMEC
IAQ69_10585	COG1136	(ABC) transporter
IAQ69_10605	COG1671	Belongs to the UPF0178 family
IAQ69_10625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_10665	COG1280	lysine exporter protein (LysE YggA)
IAQ69_10670	COG1522	sequence-specific DNA binding
IAQ69_10680	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IAQ69_10685	COG0596	Alpha beta hydrolase
IAQ69_10705	COG1113	amino acid transport
IAQ69_10710	COG1115	amino acid carrier protein
IAQ69_10730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IAQ69_10735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IAQ69_10740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAQ69_10745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAQ69_10750	COG5001	Diguanylate cyclase
IAQ69_10750	COG3300	MHYT domain
IAQ69_10770	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IAQ69_10780	COG1960	acyl-CoA dehydrogenase activity
IAQ69_10785	COG0583	DNA-binding transcription factor activity
IAQ69_10800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAQ69_10805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IAQ69_10815	COG0037	tRNA processing
IAQ69_10820	COG0741	lytic transglycosylase activity
IAQ69_10820	COG0739	heme binding
IAQ69_10820	COG1196	nuclear chromosome segregation
IAQ69_10825	COG0501	Belongs to the peptidase M48B family
IAQ69_10835	COG2239	Acts as a magnesium transporter
IAQ69_10845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAQ69_10905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAQ69_10915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAQ69_10920	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IAQ69_10945	COG0505	Belongs to the CarA family
IAQ69_10960	COG1309	transcriptional regulator
IAQ69_10965	COG0251	oxidation-reduction process
IAQ69_10990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAQ69_11015	COG0564	pseudouridine synthase activity
IAQ69_11025	COG0358	DNA primase activity
IAQ69_11030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IAQ69_11040	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IAQ69_11070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAQ69_11100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAQ69_11125	COG0586	Pfam SNARE associated Golgi protein
IAQ69_11145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAQ69_11155	COG0321	lipoyl(octanoyl) transferase activity
IAQ69_11170	COG0531	amino acid
IAQ69_11185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IAQ69_11190	COG1648	precorrin-2 dehydrogenase activity
IAQ69_11190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAQ69_11195	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAQ69_11205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IAQ69_11215	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IAQ69_11230	COG0671	phosphoesterase, PA-phosphatase related
IAQ69_11235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_11245	COG1538	Outer membrane efflux protein
IAQ69_11255	COG0393	Putative heavy-metal-binding
IAQ69_11260	COG0393	Putative heavy-metal-binding
IAQ69_11265	COG0242	peptide deformylase activity
IAQ69_11270	COG0477	Major facilitator Superfamily
IAQ69_11300	COG2199	diguanylate cyclase activity
IAQ69_11300	COG2203	Gaf domain
IAQ69_11320	COG0523	cobalamin synthesis protein
IAQ69_11335	COG0625	glutathione transferase activity
IAQ69_11340	COG0583	DNA-binding transcription factor activity
IAQ69_11345	COG2814	Major facilitator Superfamily
IAQ69_11355	COG1607	acyl-coa hydrolase
IAQ69_11365	COG1752	Esterase of the alpha-beta hydrolase superfamily
IAQ69_11370	COG2059	Chromate
IAQ69_11375	COG1115	amino acid carrier protein
IAQ69_11380	COG0786	glutamate:sodium symporter activity
IAQ69_11390	COG2814	Major facilitator Superfamily
IAQ69_11395	COG1289	transmembrane transporter activity
IAQ69_11405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAQ69_11465	COG2832	Protein of unknown function (DUF454)
IAQ69_11495	COG0840	transmembrane signaling receptor activity
IAQ69_11565	COG2358	TRAP transporter, solute receptor (TAXI family
IAQ69_11580	COG0489	protein tyrosine kinase activity
IAQ69_11590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ69_11590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAQ69_11600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAQ69_11605	COG0004	ammonium transporteR
IAQ69_11630	COG2081	HI0933 family
IAQ69_11645	COG0668	transmembrane transport
IAQ69_11665	COG0583	DNA-binding transcription factor activity
IAQ69_11670	COG1278	Cold shock
IAQ69_11705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAQ69_11710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAQ69_11715	COG0713	ATP synthesis coupled electron transport
IAQ69_11720	COG0839	Belongs to the complex I subunit 6 family
IAQ69_11725	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAQ69_11740	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IAQ69_11760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAQ69_11770	COG2205	protein histidine kinase activity
IAQ69_11775	COG0745	RESPONSE REGULATOR receiver
IAQ69_11785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAQ69_11795	COG3152	Membrane
IAQ69_11830	COG0351	phosphomethylpyrimidine kinase
IAQ69_11830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAQ69_11830	COG0352	thiamine-phosphate diphosphorylase activity
IAQ69_11850	COG2824	Alkylphosphonate utilization operon protein PhnA
IAQ69_11870	COG0564	pseudouridine synthase activity
IAQ69_11930	COG2132	Multicopper oxidase
IAQ69_11935	COG0354	folic acid binding
IAQ69_11950	COG1902	pentaerythritol trinitrate reductase activity
IAQ69_11975	COG1217	gtp-binding protein TYPA
IAQ69_11980	COG2233	PERMEase
IAQ69_11990	COG0833	amino acid
IAQ69_12010	COG0183	Belongs to the thiolase family
IAQ69_12025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAQ69_12030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAQ69_12035	COG2207	Transcriptional regulator
IAQ69_12040	COG0183	Belongs to the thiolase family
IAQ69_12045	COG1024	Enoyl-CoA hydratase
IAQ69_12045	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAQ69_12065	COG1272	protein, Hemolysin III
IAQ69_12070	COG0477	Major facilitator Superfamily
IAQ69_12080	COG1408	metallophosphoesterase
IAQ69_12085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAQ69_12095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAQ69_12130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAQ69_12135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAQ69_12145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAQ69_12150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAQ69_12155	COG0625	glutathione transferase activity
IAQ69_12160	COG2969	positive regulation of protein catabolic process
IAQ69_12175	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_12235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAQ69_12240	COG1764	response to oxidative stress
IAQ69_12280	COG0037	tRNA processing
IAQ69_12290	COG0248	Ppx GppA phosphatase
IAQ69_12315	COG0072	phenylalanine-tRNA ligase activity
IAQ69_12320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAQ69_12345	COG1238	metal cluster binding
IAQ69_12355	COG0625	glutathione transferase activity
IAQ69_12375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAQ69_12395	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_12405	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAQ69_12415	COG1704	LemA family
IAQ69_12430	COG1862	Preprotein translocase
IAQ69_12440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAQ69_12450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ69_12470	COG0784	Response regulator, receiver
IAQ69_12470	COG2205	protein histidine kinase activity
IAQ69_12470	COG5002	protein histidine kinase activity
IAQ69_12475	COG1024	Enoyl-CoA hydratase
IAQ69_12480	COG2084	Dehydrogenase
IAQ69_12485	COG3622	Belongs to the hyi family
IAQ69_12510	COG2814	Major facilitator Superfamily
IAQ69_12520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAQ69_12530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAQ69_12535	COG2003	Belongs to the UPF0758 family
IAQ69_12540	COG3781	membrane
IAQ69_12560	COG2350	Protein conserved in bacteria
IAQ69_12590	COG1607	acyl-coa hydrolase
IAQ69_12650	COG1183	phosphatidylcholine synthase activity
IAQ69_12655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IAQ69_12695	COG0741	lytic transglycosylase activity
IAQ69_12695	COG0739	heme binding
IAQ69_12695	COG1196	nuclear chromosome segregation
IAQ69_12700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAQ69_12705	COG1702	phosphate starvation-inducible protein PhoH
IAQ69_12770	COG1295	ribonuclease BN
IAQ69_12780	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAQ69_12820	COG0557	exoribonuclease II activity
IAQ69_12830	COG0339	signal peptide processing
IAQ69_12835	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IAQ69_12845	COG0697	spore germination
IAQ69_12870	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IAQ69_12875	COG1960	acyl-CoA dehydrogenase activity
IAQ69_12880	COG2072	flavoprotein involved in K transport
IAQ69_12885	COG0203	ribosomal protein L17
IAQ69_12890	COG0202	RNA polymerase activity
IAQ69_12895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAQ69_12905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAQ69_12930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAQ69_12940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAQ69_12945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAQ69_12950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAQ69_12995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAQ69_13010	COG0088	Forms part of the polypeptide exit tunnel
IAQ69_13015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAQ69_13030	COG0626	cystathionine gamma-synthase activity
IAQ69_13035	COG0433	COG0433 Predicted ATPase
IAQ69_13045	COG1959	2 iron, 2 sulfur cluster binding
IAQ69_13065	COG1301	dicarboxylic acid transport
IAQ69_13070	COG1946	Acyl-CoA thioesterase
IAQ69_13075	COG2937	Belongs to the GPAT DAPAT family
IAQ69_13085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAQ69_13090	COG1040	competence protein
IAQ69_13095	COG0494	nUDIX hydrolase
IAQ69_13105	COG0598	Magnesium transport protein CorA
IAQ69_13115	COG2854	intermembrane phospholipid transfer
IAQ69_13120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IAQ69_13125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IAQ69_13130	COG1127	ABC transporter
IAQ69_13135	COG0513	Belongs to the DEAD box helicase family
IAQ69_13145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IAQ69_13155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAQ69_13160	COG0408	coproporphyrinogen oxidase activity
IAQ69_13175	COG1960	acyl-CoA dehydrogenase activity
IAQ69_13180	COG1278	Cold shock
IAQ69_13190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAQ69_13200	COG0534	Mate efflux family protein
IAQ69_13210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAQ69_13215	COG0254	rRNA binding
IAQ69_13220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAQ69_13255	COG0628	permease
IAQ69_13265	COG1289	transmembrane transporter activity
IAQ69_13270	COG2814	Major facilitator Superfamily
IAQ69_13295	COG0277	FAD linked oxidase domain protein
IAQ69_13300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAQ69_13330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAQ69_13335	COG5380	lipid catabolic process
IAQ69_13340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IAQ69_13350	COG0335	large ribosomal subunit rRNA binding
IAQ69_13360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAQ69_13365	COG0228	four-way junction DNA binding
IAQ69_13410	COG0194	GDP metabolic process
IAQ69_13415	COG1758	RNA polymerase activity
IAQ69_13420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAQ69_13425	COG0675	Transposase, IS605 OrfB family
IAQ69_13445	COG3307	-O-antigen
IAQ69_13490	COG1704	LemA family
IAQ69_13500	COG0493	'glutamate synthase
IAQ69_13505	COG0070	glutamate synthase
IAQ69_13505	COG0069	glutamate synthase activity
IAQ69_13505	COG0067	glutamate synthase
IAQ69_13555	COG2226	methyltransferase
IAQ69_13560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAQ69_13565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAQ69_13570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAQ69_13590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAQ69_13600	COG0675	Transposase, IS605 OrfB family
IAQ69_13640	COG0488	(ABC) transporter
IAQ69_13650	COG4221	oxidoreductase activity
IAQ69_13655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAQ69_13670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAQ69_13670	COG2111	Na H antiporter
IAQ69_13675	COG1006	Multisubunit Na H antiporter MnhC subunit
IAQ69_13680	COG0651	ATP synthesis coupled electron transport
IAQ69_13685	COG1863	multisubunit Na H antiporter MnhE subunit
IAQ69_13690	COG2212	antiporter activity
IAQ69_13695	COG1320	monovalent cation:proton antiporter activity
IAQ69_13700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAQ69_13710	COG0195	Participates in both transcription termination and antitermination
IAQ69_13715	COG0779	Required for maturation of 30S ribosomal subunits
IAQ69_13750	COG0149	triose-phosphate isomerase activity
IAQ69_13770	COG0237	dephospho-CoA kinase activity
IAQ69_13780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAQ69_13785	COG3123	guanosine phosphorylase activity
IAQ69_13790	COG0497	DNA recombination
IAQ69_13795	COG2826	transposase and inactivated derivatives, IS30 family
IAQ69_13815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAQ69_13825	COG1132	(ABC) transporter
IAQ69_13835	COG1538	Outer membrane efflux protein
IAQ69_13850	COG0494	nUDIX hydrolase
IAQ69_13855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAQ69_13860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IAQ69_13865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAQ69_13875	COG0772	Belongs to the SEDS family
IAQ69_13900	COG4974	Belongs to the 'phage' integrase family
IAQ69_13905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAQ69_13915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAQ69_13925	COG1686	Belongs to the peptidase S11 family
IAQ69_13930	COG2197	response regulator
IAQ69_13935	COG2205	protein histidine kinase activity
IAQ69_13945	COG0793	Belongs to the peptidase S41A family
IAQ69_13945	COG3409	Peptidoglycan-binding domain 1 protein
IAQ69_13950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAQ69_13955	COG0795	lipopolysaccharide-transporting ATPase activity
IAQ69_13960	COG0795	lipopolysaccharide-transporting ATPase activity
IAQ69_13980	COG0586	Pfam SNARE associated Golgi protein
IAQ69_13995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAQ69_13995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAQ69_14005	COG0004	ammonium transporteR
IAQ69_14010	COG0347	Belongs to the P(II) protein family
IAQ69_14020	COG0606	chelatase, subunit chli
IAQ69_14035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IAQ69_14050	COG0318	PFAM AMP-dependent synthetase and ligase
IAQ69_14060	COG0477	Major facilitator Superfamily
IAQ69_14065	COG2860	membrane
IAQ69_14075	COG1253	flavin adenine dinucleotide binding
IAQ69_14090	COG0477	Major facilitator Superfamily
IAQ69_14100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAQ69_14105	COG0477	Major facilitator Superfamily
IAQ69_14125	COG2814	Major facilitator Superfamily
IAQ69_14175	COG0758	DNA mediated transformation
IAQ69_14185	COG0697	spore germination
IAQ69_14190	COG0386	Belongs to the glutathione peroxidase family
IAQ69_14205	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_14215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAQ69_14265	COG1121	(ABC) transporter
IAQ69_14270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAQ69_14275	COG1683	Conserved Protein
IAQ69_14280	COG1280	lysine exporter protein (LysE YggA)
IAQ69_14285	COG2837	iron assimilation
IAQ69_14300	COG0436	Aminotransferase
IAQ69_14305	COG0534	Mate efflux family protein
IAQ69_14330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAQ69_14340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAQ69_14410	COG3706	GGDEF domain
IAQ69_14420	COG1715	Restriction endonuclease
IAQ69_14425	COG0519	Catalyzes the synthesis of GMP from XMP
IAQ69_14425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAQ69_14430	COG0586	Pfam SNARE associated Golgi protein
IAQ69_14445	COG1192	Involved in chromosome partitioning
IAQ69_14480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IAQ69_14495	COG4716	Myosin-crossreactive antigen
IAQ69_14515	COG0494	nUDIX hydrolase
IAQ69_14525	COG3293	Transposase
IAQ69_14545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IAQ69_14555	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IAQ69_14560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAQ69_14570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAQ69_14600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAQ69_14610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAQ69_14625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAQ69_14635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IAQ69_14645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IAQ69_14650	COG0438	transferase activity, transferring glycosyl groups
IAQ69_14660	COG0367	asparagine synthase
IAQ69_14675	COG0438	transferase activity, transferring glycosyl groups
IAQ69_14680	COG0438	transferase activity, transferring glycosyl groups
IAQ69_14720	COG1091	dTDP-4-dehydrorhamnose reductase activity
IAQ69_14735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IAQ69_14750	COG1596	polysaccharide export
IAQ69_14825	COG1194	a g-specific adenine glycosylase
IAQ69_14830	COG0739	heme binding
IAQ69_14840	COG2818	Glycosylase
IAQ69_14845	COG1064	alcohol dehydrogenase
IAQ69_14850	COG0583	DNA-binding transcription factor activity
IAQ69_14855	COG0656	L-ascorbic acid biosynthetic process
IAQ69_14870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IAQ69_14900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAQ69_14915	COG2233	PERMEase
IAQ69_14940	COG0129	dihydroxy-acid dehydratase activity
IAQ69_14945	COG0129	dihydroxy-acid dehydratase activity
IAQ69_14960	COG0428	transporter
IAQ69_14970	COG0733	neurotransmitter:sodium symporter activity
IAQ69_14975	COG1012	belongs to the aldehyde dehydrogenase family
IAQ69_14985	COG0693	protein deglycase activity
IAQ69_15000	COG2814	Major facilitator Superfamily
IAQ69_15005	COG2814	Major facilitator Superfamily
IAQ69_15040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAQ69_15045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IAQ69_15050	COG2951	lytic endotransglycosylase activity
IAQ69_15055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAQ69_15070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAQ69_15095	COG2814	Major facilitator Superfamily
IAQ69_15100	COG0861	Integral membrane protein TerC family
IAQ69_15105	COG0402	S-adenosylhomocysteine deaminase activity
IAQ69_15120	COG0675	Transposase, IS605 OrfB family
IAQ69_15135	COG0675	Transposase, IS605 OrfB family
IAQ69_15150	COG2814	Major facilitator Superfamily
IAQ69_15155	COG3385	transposase activity
IAQ69_15165	COG0706	membrane insertase activity
IAQ69_15170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IAQ69_15175	COG0594	ribonuclease P activity
IAQ69_15210	COG1192	Involved in chromosome partitioning
IAQ69_15245	COG1346	cytolysis
IAQ69_15250	COG1380	Effector of murein hydrolase LrgA
IAQ69_15255	COG0583	DNA-binding transcription factor activity
IAQ69_15260	COG1309	transcriptional regulator
IAQ69_15265	COG0604	alcohol dehydrogenase
IAQ69_15300	COG1373	ATPase (AAA superfamily
IAQ69_15355	COG2072	flavoprotein involved in K transport
IAQ69_15360	COG0492	ferredoxin-NADP+ reductase activity
IAQ69_15365	COG0431	NADPH-dependent FMN reductase
IAQ69_15370	COG0798	PFAM Bile acid sodium symporter
IAQ69_15380	COG0640	Transcriptional regulator
IAQ69_15390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAQ69_15400	COG4716	Myosin-crossreactive antigen
IAQ69_15415	COG4993	Dehydrogenase
IAQ69_15495	COG2963	transposase activity
IAQ69_15625	COG4221	oxidoreductase activity
IAQ69_15665	COG1660	Displays ATPase and GTPase activities
IAQ69_15700	COG4372	Transposase
IAQ69_15710	COG2963	transposase activity
IAQ69_15730	COG0488	(ABC) transporter
IAQ69_15735	COG3173	Aminoglycoside phosphotransferase
IAQ69_15750	COG0583	DNA-binding transcription factor activity
IAQ69_15810	COG3657	addiction module killer protein
IAQ69_15815	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAQ69_15850	COG3077	Addiction module antitoxin, RelB DinJ family
IAQ69_15870	COG4372	Transposase
IAQ69_15895	COG0640	Transcriptional regulator
IAQ69_15900	COG0798	PFAM Bile acid sodium symporter
IAQ69_15905	COG0431	NADPH-dependent FMN reductase
IAQ69_15925	COG3188	usher protein
IAQ69_15950	COG2226	methyltransferase
IAQ69_15950	COG2267	carboxylic ester hydrolase activity
IAQ69_15955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAQ69_15955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAQ69_15965	COG4106	trans-aconitate 2-methyltransferase activity
IAQ69_16040	COG1063	alcohol dehydrogenase
IAQ69_16050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAQ69_16055	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAQ69_16060	COG0022	dehydrogenase e1 component
IAQ69_16065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAQ69_16070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAQ69_16130	COG1454	alcohol dehydrogenase
IAQ69_16135	COG0675	Transposase, IS605 OrfB family
IAQ69_16150	COG4372	Transposase
IAQ69_16160	COG2963	transposase activity
IAQ69_16180	COG0582	viral genome integration into host DNA
IAQ69_16195	COG2369	cell adhesion
IAQ69_16220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAQ69_16290	COG2801	Transposase and inactivated derivatives
IAQ69_16355	COG0583	DNA-binding transcription factor activity
IAQ69_16410	COG3173	Aminoglycoside phosphotransferase
IAQ69_16585	COG1660	Displays ATPase and GTPase activities
IAQ69_16605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAQ69_16630	COG0659	secondary active sulfate transmembrane transporter activity
IAQ69_16730	COG2433	Pfam Transposase IS66
IAQ69_16790	COG2963	transposase activity